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Search of human proteins with 222136596
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222136596 transmembrane 6 superfamily member 1 isoform 1
[Homo sapiens]
(370 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222136596 transmembrane 6 superfamily member 1 isoform 1 [Hom... 756 0.0
gi|222136594 transmembrane 6 superfamily member 1 isoform 2 [Hom... 674 0.0
gi|112181177 transmembrane 6 superfamily member 2 [Homo sapiens] 386 e-107
gi|194239633 solute carrier family 44, member 5 isoform B [Homo ... 37 0.037
gi|194239631 solute carrier family 44, member 5 isoform A [Homo ... 37 0.037
gi|109948302 transmembrane protein 97 [Homo sapiens] 36 0.063
gi|105990541 ATP-binding cassette, sub-family A member 4 [Homo s... 32 1.2
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 30 3.5
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 29 5.9
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 29 5.9
gi|196123581 cytochrome c oxidase subunit I [Homo sapiens neande... 29 7.7
gi|251831109 cytochrome c oxidase subunit I [Homo sapiens] 29 7.7
gi|239757068 PREDICTED: hypothetical protein [Homo sapiens] 29 7.7
gi|239751578 PREDICTED: hypothetical protein [Homo sapiens] 29 7.7
gi|239746090 PREDICTED: hypothetical protein XP_002343655 [Homo ... 29 7.7
>gi|222136596 transmembrane 6 superfamily member 1 isoform 1 [Homo
sapiens]
Length = 370
Score = 756 bits (1951), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MSASAATGVFVLSLSAIPVTYVFNHLAAQHDSWTIVGVAALILFLVALLARVLVKRKPPR 60
MSASAATGVFVLSLSAIPVTYVFNHLAAQHDSWTIVGVAALILFLVALLARVLVKRKPPR
Sbjct: 1 MSASAATGVFVLSLSAIPVTYVFNHLAAQHDSWTIVGVAALILFLVALLARVLVKRKPPR 60
Query: 61 DPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHY 120
DPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHY
Sbjct: 61 DPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHY 120
Query: 121 LMYLVMVAAIAWEETYRTIGLYWVGSIIMSVVVFVPGNIVGKYGTRICPAFFLSIPYTCL 180
LMYLVMVAAIAWEETYRTIGLYWVGSIIMSVVVFVPGNIVGKYGTRICPAFFLSIPYTCL
Sbjct: 121 LMYLVMVAAIAWEETYRTIGLYWVGSIIMSVVVFVPGNIVGKYGTRICPAFFLSIPYTCL 180
Query: 181 PVWAGFRIYNQPSENYNYPSKVIQEAQAKDLLRRPFDLMLVVCLLLATGFCLFRGLIALD 240
PVWAGFRIYNQPSENYNYPSKVIQEAQAKDLLRRPFDLMLVVCLLLATGFCLFRGLIALD
Sbjct: 181 PVWAGFRIYNQPSENYNYPSKVIQEAQAKDLLRRPFDLMLVVCLLLATGFCLFRGLIALD 240
Query: 241 CPSELCRLYTQFQEPYLKDPAAYPKIQMLAYMFYSVPYFVTALYGLVVPGCSWMPDITLI 300
CPSELCRLYTQFQEPYLKDPAAYPKIQMLAYMFYSVPYFVTALYGLVVPGCSWMPDITLI
Sbjct: 241 CPSELCRLYTQFQEPYLKDPAAYPKIQMLAYMFYSVPYFVTALYGLVVPGCSWMPDITLI 300
Query: 301 HAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQLLAYRCIYKPEFF 360
HAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQLLAYRCIYKPEFF
Sbjct: 301 HAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQLLAYRCIYKPEFF 360
Query: 361 IKTKAEEKVE 370
IKTKAEEKVE
Sbjct: 361 IKTKAEEKVE 370
>gi|222136594 transmembrane 6 superfamily member 1 isoform 2 [Homo
sapiens]
Length = 339
Score = 674 bits (1739), Expect = 0.0
Identities = 339/370 (91%), Positives = 339/370 (91%), Gaps = 31/370 (8%)
Query: 1 MSASAATGVFVLSLSAIPVTYVFNHLAAQHDSWTIVGVAALILFLVALLARVLVKRKPPR 60
MSASAATGVFVLSLSAIPVTYVFNHLAAQHDSWTIVGVAALILFLVALLARVLVKRKPPR
Sbjct: 1 MSASAATGVFVLSLSAIPVTYVFNHLAAQHDSWTIVGVAALILFLVALLARVLVKRKPPR 60
Query: 61 DPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHY 120
DPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHY
Sbjct: 61 DPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHY 120
Query: 121 LMYLVMVAAIAWEETYRTIGLYWVGSIIMSVVVFVPGNIVGKYGTRICPAFFLSIPYTCL 180
LMYLVMVAAIAWEETYRTIGLYWVGSIIMSVVVFVPGNIVGKYGTRICPAFFLSIPYTCL
Sbjct: 121 LMYLVMVAAIAWEETYRTIGLYWVGSIIMSVVVFVPGNIVGKYGTRICPAFFLSIPYTCL 180
Query: 181 PVWAGFRIYNQPSENYNYPSKVIQEAQAKDLLRRPFDLMLVVCLLLATGFCLFRGLIALD 240
PVWAGFRIYNQPSENYNYPSKVIQEAQAKDLLRRPFDLMLVVCLLLATGFCLFRGL
Sbjct: 181 PVWAGFRIYNQPSENYNYPSKVIQEAQAKDLLRRPFDLMLVVCLLLATGFCLFRGL---- 236
Query: 241 CPSELCRLYTQFQEPYLKDPAAYPKIQMLAYMFYSVPYFVTALYGLVVPGCSWMPDITLI 300
MLAYMFYSVPYFVTALYGLVVPGCSWMPDITLI
Sbjct: 237 ---------------------------MLAYMFYSVPYFVTALYGLVVPGCSWMPDITLI 269
Query: 301 HAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQLLAYRCIYKPEFF 360
HAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQLLAYRCIYKPEFF
Sbjct: 270 HAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQLLAYRCIYKPEFF 329
Query: 361 IKTKAEEKVE 370
IKTKAEEKVE
Sbjct: 330 IKTKAEEKVE 339
>gi|112181177 transmembrane 6 superfamily member 2 [Homo sapiens]
Length = 377
Score = 386 bits (991), Expect = e-107
Identities = 185/353 (52%), Positives = 243/353 (68%), Gaps = 2/353 (0%)
Query: 9 VFVLSLSAIPVTYVFNHLAA-QHDSWTIVGVAALILFLVALLARVLVKRKPPRDPLFYVY 67
+ LSLSA+PV+Y NH++A H W + ++ALIL L+ + L + DPL+ V+
Sbjct: 10 IAALSLSALPVSYALNHVSALSHPLWVAL-MSALILGLLFVAVYSLSHGEVSYDPLYAVF 68
Query: 68 AVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHYLMYLVMV 127
AVF FTSVV+LII L++D + GFM Y +EGEPYL TA+G ICYWDG+ HYL+YL M
Sbjct: 69 AVFAFTSVVDLIIALQEDSYVVGFMEFYTKEGEPYLRTAHGVFICYWDGTVHYLLYLAMA 128
Query: 128 AAIAWEETYRTIGLYWVGSIIMSVVVFVPGNIVGKYGTRICPAFFLSIPYTCLPVWAGFR 187
AI + YR GLYW+GS MS++VF+ GNI+GKY + I PAFFL+IPY +P WAG +
Sbjct: 129 GAICRRKRYRNFGLYWLGSFAMSILVFLTGNILGKYSSEIRPAFFLTIPYLLVPCWAGMK 188
Query: 188 IYNQPSENYNYPSKVIQEAQAKDLLRRPFDLMLVVCLLLATGFCLFRGLIALDCPSELCR 247
+++QP + ++QE Q K LL+RP DL LV+ L+LA F LFRGL+ LDCP++ C
Sbjct: 189 VFSQPRALTRCTANMVQEEQRKGLLQRPADLALVIYLILAGFFTLFRGLVVLDCPTDACF 248
Query: 248 LYTQFQEPYLKDPAAYPKIQMLAYMFYSVPYFVTALYGLVVPGCSWMPDITLIHAGGLAQ 307
+Y EPYL+DP AYPK+QML YMFY +P+ A Y L PGCSW+PD L+ AGG+ Q
Sbjct: 249 VYIYQYEPYLRDPVAYPKVQMLMYMFYVLPFCGLAAYALTFPGCSWLPDWALVFAGGIGQ 308
Query: 308 AQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQLLAYRCIYKPEFF 360
AQFSH+GAS+H RT + YRVPE+ F N+ Y + P LLAYRC+ P FF
Sbjct: 309 AQFSHMGASMHLRTPFTYRVPEDTWGCFFVCNLLYALGPHLLAYRCLQWPAFF 361
>gi|194239633 solute carrier family 44, member 5 isoform B [Homo
sapiens]
Length = 717
Score = 36.6 bits (83), Expect = 0.037
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 62 PLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEP------YLNTAYGHMICYWD 115
P F+VY +F F ++N +I L Q + F T+Y +P L TA+G I Y
Sbjct: 454 PTFHVYNLFVFLWLINFVIALGQCALAGAFATYYWAMKKPDDIPRYPLFTAFGRAIRYHT 513
Query: 116 GS 117
GS
Sbjct: 514 GS 515
>gi|194239631 solute carrier family 44, member 5 isoform A [Homo
sapiens]
Length = 719
Score = 36.6 bits (83), Expect = 0.037
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 62 PLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEP------YLNTAYGHMICYWD 115
P F+VY +F F ++N +I L Q + F T+Y +P L TA+G I Y
Sbjct: 454 PTFHVYNLFVFLWLINFVIALGQCALAGAFATYYWAMKKPDDIPRYPLFTAFGRAIRYHT 513
Query: 116 GS 117
GS
Sbjct: 514 GS 515
>gi|109948302 transmembrane protein 97 [Homo sapiens]
Length = 176
Score = 35.8 bits (81), Expect = 0.063
Identities = 13/52 (25%), Positives = 29/52 (55%)
Query: 251 QFQEPYLKDPAAYPKIQMLAYMFYSVPYFVTALYGLVVPGCSWMPDITLIHA 302
+F++P L++P A+ K + + + +P+F A Y + C W+ +I++
Sbjct: 53 EFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYS 104
>gi|105990541 ATP-binding cassette, sub-family A member 4 [Homo
sapiens]
Length = 2273
Score = 31.6 bits (70), Expect = 1.2
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 4/77 (5%)
Query: 209 KDLLRRPFDLMLVVCLLLATGFCLFRGLIALDCPSELCRLYTQFQEPYLKDPAAYPKI-- 266
+ LLR F+ +L L++ FCL RGLI L + +Y +F E + +P + I
Sbjct: 1820 RTLLR--FNAVLRKLLIVFPHFCLGRGLIDLALSQAVTDVYARFGEEHSANPFHWDLIGK 1877
Query: 267 QMLAYMFYSVPYFVTAL 283
+ A + V YF+ L
Sbjct: 1878 NLFAMVVEGVVYFLLTL 1894
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 30.0 bits (66), Expect = 3.5
Identities = 17/61 (27%), Positives = 34/61 (55%), Gaps = 6/61 (9%)
Query: 33 WTIVGVAALILFLVALLARVLVKRKPPRDPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFM 92
++++G+ +LFL A++ R+ V R P+ Y + +GF+ V I+ ++ GF+
Sbjct: 137 YSVIGIPFTLLFLTAVVQRITV--HVTRRPVLYFHIRWGFSKQVVAIV----HAVLLGFV 190
Query: 93 T 93
T
Sbjct: 191 T 191
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 29.3 bits (64), Expect = 5.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Query: 195 NYNYPSKVIQEAQAKDLLRR-----PFDLMLVVCLLLATGFCLFRGLIALDCPS 243
NYNY +++ A D+ R L++ L LA FCL G+IALD P+
Sbjct: 1042 NYNYRVVMLKGDTALDMRGRCSAGQKVLASLIIRLALAETFCLNCGIIALDEPT 1095
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 29.3 bits (64), Expect = 5.9
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Query: 195 NYNYPSKVIQEAQAKDLLRR-----PFDLMLVVCLLLATGFCLFRGLIALDCPS 243
NYNY +++ A D+ R L++ L LA FCL G+IALD P+
Sbjct: 1181 NYNYRVVMLKGDTALDMRGRCSAGQKVLASLIIRLALAETFCLNCGIIALDEPT 1234
>gi|196123581 cytochrome c oxidase subunit I [Homo sapiens
neanderthalensis]
Length = 513
Score = 28.9 bits (63), Expect = 7.7
Identities = 27/122 (22%), Positives = 49/122 (40%), Gaps = 23/122 (18%)
Query: 33 WTIVGVAALILFLVALLARVLVKRKPPR-------------DPLFYVYAVFGFTSVVNLI 79
W+++ A L+L + +LA + R DP+ Y + + F I
Sbjct: 186 WSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYI 245
Query: 80 IGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHYLMYLVMVAAIAWEETYRTI 139
+ L G+I +T+Y + EP +G+M W +M + + I W T+
Sbjct: 246 LILPGFGMISHIVTYYSGKKEP-----FGYMGMVW-----AMMSIGFLGFIVWAHHMFTV 295
Query: 140 GL 141
G+
Sbjct: 296 GM 297
>gi|251831109 cytochrome c oxidase subunit I [Homo sapiens]
Length = 513
Score = 28.9 bits (63), Expect = 7.7
Identities = 27/122 (22%), Positives = 49/122 (40%), Gaps = 23/122 (18%)
Query: 33 WTIVGVAALILFLVALLARVLVKRKPPR-------------DPLFYVYAVFGFTSVVNLI 79
W+++ A L+L + +LA + R DP+ Y + + F I
Sbjct: 186 WSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYI 245
Query: 80 IGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHYLMYLVMVAAIAWEETYRTI 139
+ L G+I +T+Y + EP +G+M W +M + + I W T+
Sbjct: 246 LILPGFGMISHIVTYYSGKKEP-----FGYMGMVW-----AMMSIGFLGFIVWAHHMFTV 295
Query: 140 GL 141
G+
Sbjct: 296 GM 297
>gi|239757068 PREDICTED: hypothetical protein [Homo sapiens]
Length = 312
Score = 28.9 bits (63), Expect = 7.7
Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
Query: 288 VPGCSWMPDITLIHAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQ 347
VPGC WM + GL + + G R A++ R+P A + L +++ + LP
Sbjct: 167 VPGCGWMGRVP-----GLG-GEDARCGGGPRGRGAHISRIPLVAPLRQLIMDVLHHYLPV 220
Query: 348 LL 349
++
Sbjct: 221 IV 222
>gi|239751578 PREDICTED: hypothetical protein [Homo sapiens]
Length = 312
Score = 28.9 bits (63), Expect = 7.7
Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
Query: 288 VPGCSWMPDITLIHAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQ 347
VPGC WM + GL + + G R A++ R+P A + L +++ + LP
Sbjct: 167 VPGCGWMGRVP-----GLG-GEDARCGGGPRGRGAHISRIPLVAPLRQLIMDVLHHYLPV 220
Query: 348 LL 349
++
Sbjct: 221 IV 222
>gi|239746090 PREDICTED: hypothetical protein XP_002343655 [Homo
sapiens]
Length = 312
Score = 28.9 bits (63), Expect = 7.7
Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
Query: 288 VPGCSWMPDITLIHAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQ 347
VPGC WM + GL + + G R A++ R+P A + L +++ + LP
Sbjct: 167 VPGCGWMGRVP-----GLG-GEDARCGGGPRGRGAHISRIPLVAPLRQLIMDVLHHYLPV 220
Query: 348 LL 349
++
Sbjct: 221 IV 222
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.143 0.454
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,737,214
Number of Sequences: 37866
Number of extensions: 579740
Number of successful extensions: 1262
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1255
Number of HSP's gapped (non-prelim): 15
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.