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Search of human proteins with 22208987
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
(248 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 533 e-152
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 505 e-143
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 245 3e-65
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 244 4e-65
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 240 1e-63
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 240 1e-63
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 240 1e-63
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 229 1e-60
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 219 2e-57
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 219 2e-57
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 219 2e-57
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 219 2e-57
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 219 2e-57
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 219 2e-57
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 219 2e-57
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 218 3e-57
gi|11496281 kallikrein 13 precursor [Homo sapiens] 218 4e-57
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 216 1e-56
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 216 1e-56
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 213 2e-55
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 213 2e-55
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 193 1e-49
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 192 3e-49
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 191 5e-49
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 190 9e-49
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 189 3e-48
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 187 6e-48
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 181 4e-46
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 177 6e-45
gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 157 6e-39
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 533 bits (1374), Expect = e-152
Identities = 248/248 (100%), Positives = 248/248 (100%)
Query: 1 MGLSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTA 60
MGLSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTA
Sbjct: 1 MGLSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTA 60
Query: 61 AHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRV 120
AHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRV
Sbjct: 61 AHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRV 120
Query: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180
TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI
Sbjct: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180
Query: 181 TSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDW 240
TSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDW
Sbjct: 181 TSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDW 240
Query: 241 IRMIMRNN 248
IRMIMRNN
Sbjct: 241 IRMIMRNN 248
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 505 bits (1301), Expect = e-143
Identities = 235/235 (100%), Positives = 235/235 (100%)
Query: 1 MGLSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTA 60
MGLSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTA
Sbjct: 1 MGLSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTA 60
Query: 61 AHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRV 120
AHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRV
Sbjct: 61 AHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRV 120
Query: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180
TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI
Sbjct: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180
Query: 181 TSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYIC 235
TSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYIC
Sbjct: 181 TSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYIC 235
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 245 bits (625), Expect = 3e-65
Identities = 123/245 (50%), Positives = 147/245 (60%), Gaps = 5/245 (2%)
Query: 5 IFLLL---CVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAA 61
+FLLL G S+A K+ G EC +SQPWQ LF+G L CGGVL+ WVLTAA
Sbjct: 13 MFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAA 72
Query: 62 HCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTS-HEHDLRLLRLRLPVRV 120
HC +Y VRLG+HSL D EQ S+ HP Y + H HDL LL+LR +
Sbjct: 73 HCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASL 132
Query: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180
S V+P+ L + C G +C VSGWG PR FPD L C + I C YPG+I
Sbjct: 133 GSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQI 192
Query: 181 TSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDW 240
T MVCAG G D CQGDSGGPLVC G LQG+ SWGS PCG+ PGVYT IC+Y+DW
Sbjct: 193 TDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGS-DPCGRSDKPGVYTNICRYLDW 251
Query: 241 IRMIM 245
I+ I+
Sbjct: 252 IKKII 256
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 244 bits (624), Expect = 4e-65
Identities = 119/234 (50%), Positives = 142/234 (60%), Gaps = 2/234 (0%)
Query: 13 GLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRL 72
G S+A K+ G EC +SQPWQ LF+G L CGGVL+ WVLTAAHC +Y VRL
Sbjct: 69 GHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRL 128
Query: 73 GEHSLSQLDWTEQIRHSGFSVTHPGYLGASTS-HEHDLRLLRLRLPVRVTSSVQPLPLPN 131
G+HSL D EQ S+ HP Y + H HDL LL+LR + S V+P+ L +
Sbjct: 129 GDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLAD 188
Query: 132 DCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVP 191
C G +C VSGWG PR FPD L C + I C YPG+IT MVCAG
Sbjct: 189 HCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSK 248
Query: 192 GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIM 245
G D CQGDSGGPLVC G LQG+ SWGS PCG+ PGVYT IC+Y+DWI+ I+
Sbjct: 249 GADTCQGDSGGPLVCDGALQGITSWGS-DPCGRSDKPGVYTNICRYLDWIKKII 301
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 240 bits (612), Expect = 1e-63
Identities = 120/249 (48%), Positives = 155/249 (62%), Gaps = 5/249 (2%)
Query: 3 LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
L + LL GL T +I G EC +SQPWQ LFE T L CG LI RW+LTAAH
Sbjct: 4 LQLILLALATGLVGGET-RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 62
Query: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGA--STSHEHDLRLLRLRLPVRV 120
C RY V LG+H+L + + EQ R + S HPG+ + + H +D+ L+++ PV +
Sbjct: 63 CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 122
Query: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180
T +V+PL L + C TAGT C +SGWG T+ P+ P L+C N++I+ H C YPG I
Sbjct: 123 TWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNI 182
Query: 181 TSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVD 239
T MVCA G+D+CQGDSGGPLVC LQG++SWG PC PGVYT +CKYVD
Sbjct: 183 TDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQ-DPCAITRKPGVYTKVCKYVD 241
Query: 240 WIRMIMRNN 248
WI+ M+NN
Sbjct: 242 WIQETMKNN 250
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 240 bits (612), Expect = 1e-63
Identities = 120/249 (48%), Positives = 155/249 (62%), Gaps = 5/249 (2%)
Query: 3 LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
L + LL GL T +I G EC +SQPWQ LFE T L CG LI RW+LTAAH
Sbjct: 36 LQLILLALATGLVGGET-RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 94
Query: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGA--STSHEHDLRLLRLRLPVRV 120
C RY V LG+H+L + + EQ R + S HPG+ + + H +D+ L+++ PV +
Sbjct: 95 CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 154
Query: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180
T +V+PL L + C TAGT C +SGWG T+ P+ P L+C N++I+ H C YPG I
Sbjct: 155 TWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNI 214
Query: 181 TSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVD 239
T MVCA G+D+CQGDSGGPLVC LQG++SWG PC PGVYT +CKYVD
Sbjct: 215 TDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQ-DPCAITRKPGVYTKVCKYVD 273
Query: 240 WIRMIMRNN 248
WI+ M+NN
Sbjct: 274 WIQETMKNN 282
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 240 bits (612), Expect = 1e-63
Identities = 120/249 (48%), Positives = 155/249 (62%), Gaps = 5/249 (2%)
Query: 3 LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
L + LL GL T +I G EC +SQPWQ LFE T L CG LI RW+LTAAH
Sbjct: 4 LQLILLALATGLVGGET-RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 62
Query: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGA--STSHEHDLRLLRLRLPVRV 120
C RY V LG+H+L + + EQ R + S HPG+ + + H +D+ L+++ PV +
Sbjct: 63 CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 122
Query: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180
T +V+PL L + C TAGT C +SGWG T+ P+ P L+C N++I+ H C YPG I
Sbjct: 123 TWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNI 182
Query: 181 TSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVD 239
T MVCA G+D+CQGDSGGPLVC LQG++SWG PC PGVYT +CKYVD
Sbjct: 183 TDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQ-DPCAITRKPGVYTKVCKYVD 241
Query: 240 WIRMIMRNN 248
WI+ M+NN
Sbjct: 242 WIQETMKNN 250
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 229 bits (585), Expect = 1e-60
Identities = 121/257 (47%), Positives = 153/257 (59%), Gaps = 16/257 (6%)
Query: 5 IFLLLCVLGLSQAATP--KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
+ L L L S AA K+ G EC +SQPWQV L+E CG LI WVL+AAH
Sbjct: 3 LLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
Query: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTS 122
C VRLGEH+L + D EQ+R + + HP Y + SH +D+ LLRL P R+
Sbjct: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRY--EARSHRNDIMLLRLVQPARLNP 120
Query: 123 SVQPLPLPNDCATAGTECHVSGWGITNH--------PRN--PFPDLLQCLNLSIVSHATC 172
V+P LP C G C VSGWG+ +H PR+ PD L C N+SI+S +C
Sbjct: 121 QVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSC 180
Query: 173 HGVYPGRITSNMVCAGGV-PGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVY 231
YPGR+T+ MVCAG G ++C+GDSGGPLVCGG+LQG+VSWG V PC PGVY
Sbjct: 181 DKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDV-PCDNTTKPGVY 239
Query: 232 TYICKYVDWIRMIMRNN 248
T +C Y++WIR M+ N
Sbjct: 240 TKVCHYLEWIRETMKRN 256
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 219 bits (558), Expect = 2e-57
Identities = 107/236 (45%), Positives = 148/236 (62%), Gaps = 5/236 (2%)
Query: 15 SQAATPKIFNGTECGRNSQPWQVGLF-EGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLG 73
S ++ +I NG++C ++QPWQ L L CG VL+ +W+LTAAHC + VRLG
Sbjct: 60 SDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLG 119
Query: 74 EHSLSQLDWTEQIRHSGF-SVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPND 132
+SLS + + Q G S+ HPGY + H +DL L++L +R T V+P+ + +
Sbjct: 120 HYSLSPVYESGQQMFQGVKSIPHPGY--SHPGHSNDLMLIKLNRRIRPTKDVRPINVSSH 177
Query: 133 CATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVPG 192
C +AGT+C VSGWG T P+ FP +LQCLN+S++S C YP +I M CAG G
Sbjct: 178 CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAG 237
Query: 193 QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN 248
+D+CQGDSGGP+VC G LQGLVSWG PC + PGVYT +CK+ WI+ ++ N
Sbjct: 238 RDSCQGDSGGPVVCNGSLQGLVSWGDY-PCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 219 bits (558), Expect = 2e-57
Identities = 107/236 (45%), Positives = 148/236 (62%), Gaps = 5/236 (2%)
Query: 15 SQAATPKIFNGTECGRNSQPWQVGLF-EGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLG 73
S ++ +I NG++C ++QPWQ L L CG VL+ +W+LTAAHC + VRLG
Sbjct: 60 SDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLG 119
Query: 74 EHSLSQLDWTEQIRHSGF-SVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPND 132
+SLS + + Q G S+ HPGY + H +DL L++L +R T V+P+ + +
Sbjct: 120 HYSLSPVYESGQQMFQGVKSIPHPGY--SHPGHSNDLMLIKLNRRIRPTKDVRPINVSSH 177
Query: 133 CATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVPG 192
C +AGT+C VSGWG T P+ FP +LQCLN+S++S C YP +I M CAG G
Sbjct: 178 CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAG 237
Query: 193 QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN 248
+D+CQGDSGGP+VC G LQGLVSWG PC + PGVYT +CK+ WI+ ++ N
Sbjct: 238 RDSCQGDSGGPVVCNGSLQGLVSWGDY-PCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 219 bits (558), Expect = 2e-57
Identities = 107/236 (45%), Positives = 148/236 (62%), Gaps = 5/236 (2%)
Query: 15 SQAATPKIFNGTECGRNSQPWQVGLF-EGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLG 73
S ++ +I NG++C ++QPWQ L L CG VL+ +W+LTAAHC + VRLG
Sbjct: 60 SDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLG 119
Query: 74 EHSLSQLDWTEQIRHSGF-SVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPND 132
+SLS + + Q G S+ HPGY + H +DL L++L +R T V+P+ + +
Sbjct: 120 HYSLSPVYESGQQMFQGVKSIPHPGY--SHPGHSNDLMLIKLNRRIRPTKDVRPINVSSH 177
Query: 133 CATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVPG 192
C +AGT+C VSGWG T P+ FP +LQCLN+S++S C YP +I M CAG G
Sbjct: 178 CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAG 237
Query: 193 QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN 248
+D+CQGDSGGP+VC G LQGLVSWG PC + PGVYT +CK+ WI+ ++ N
Sbjct: 238 RDSCQGDSGGPVVCNGSLQGLVSWGDY-PCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 219 bits (557), Expect = 2e-57
Identities = 112/230 (48%), Positives = 138/230 (60%), Gaps = 8/230 (3%)
Query: 25 GTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTE 84
G+ C R SQPWQV LF G S C GVL+D WVLTAAHC W R+G+ L L E
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
Query: 85 QIRHSGFSVTHPGYLGAS------TSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGT 138
Q+R + SV HP Y S + EHDL LL+L PV + V+ L LP CA G
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Query: 139 ECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVPGQDACQG 198
+C V+GWG T R + L C +++I+S C YPG +T+NM+CAG GQD CQ
Sbjct: 168 QCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQS 227
Query: 199 DSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN 248
DSGGPLVC LQG++SWG V PCG P VYT ICKY+ WI ++R+N
Sbjct: 228 DSGGPLVCDETLQGILSWG-VYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 219 bits (557), Expect = 2e-57
Identities = 112/230 (48%), Positives = 138/230 (60%), Gaps = 8/230 (3%)
Query: 25 GTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTE 84
G+ C R SQPWQV LF G S C GVL+D WVLTAAHC W R+G+ L L E
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
Query: 85 QIRHSGFSVTHPGYLGAS------TSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGT 138
Q+R + SV HP Y S + EHDL LL+L PV + V+ L LP CA G
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Query: 139 ECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVPGQDACQG 198
+C V+GWG T R + L C +++I+S C YPG +T+NM+CAG GQD CQ
Sbjct: 168 QCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQS 227
Query: 199 DSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN 248
DSGGPLVC LQG++SWG V PCG P VYT ICKY+ WI ++R+N
Sbjct: 228 DSGGPLVCDETLQGILSWG-VYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 219 bits (557), Expect = 2e-57
Identities = 112/230 (48%), Positives = 138/230 (60%), Gaps = 8/230 (3%)
Query: 25 GTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTE 84
G+ C R SQPWQV LF G S C GVL+D WVLTAAHC W R+G+ L L E
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
Query: 85 QIRHSGFSVTHPGYLGAS------TSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGT 138
Q+R + SV HP Y S + EHDL LL+L PV + V+ L LP CA G
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Query: 139 ECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVPGQDACQG 198
+C V+GWG T R + L C +++I+S C YPG +T+NM+CAG GQD CQ
Sbjct: 168 QCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQS 227
Query: 199 DSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN 248
DSGGPLVC LQG++SWG V PCG P VYT ICKY+ WI ++R+N
Sbjct: 228 DSGGPLVCDETLQGILSWG-VYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 219 bits (557), Expect = 2e-57
Identities = 115/250 (46%), Positives = 147/250 (58%), Gaps = 5/250 (2%)
Query: 1 MGLSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTA 60
+GL LL + G A T I EC NSQPWQ GLF T L CG LI RW+LTA
Sbjct: 3 LGLLCALLSLLAGHGWADTRAI-GAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTA 61
Query: 61 AHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLG--ASTSHEHDLRLLRLRLPV 118
AHC WVRLGEH L + + EQ+ HPG+ ++ H D+ L+RL
Sbjct: 62 AHCRKPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQA 121
Query: 119 RVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPG 178
R++ +VQPL L C + G +C +SGWG + P+ FP LQC N+SI+ + CH YPG
Sbjct: 122 RLSPAVQPLNLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPG 181
Query: 179 RITSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKY 237
I+ +M+CAG G+ +CQGDSGGPLVC G L G+VS G PC + P VYT +C Y
Sbjct: 182 HISDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVS-GGAEPCSRPRRPAVYTSVCHY 240
Query: 238 VDWIRMIMRN 247
+DWI+ IM N
Sbjct: 241 LDWIQEIMEN 250
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 218 bits (556), Expect = 3e-57
Identities = 119/254 (46%), Positives = 152/254 (59%), Gaps = 15/254 (5%)
Query: 5 IFLLLCVLGL-------SQAATPKIFNGTECGRNSQPWQVGLFEGTSLR--CGGVLIDHR 55
+FLLL L + SQ KI G C R+SQPWQ L G R CGG L+ +
Sbjct: 17 MFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQ 76
Query: 56 WVLTAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLR 115
WV+TAAHC V LG+H+L + + T+Q+ VTHP Y S +H++DL LL+L+
Sbjct: 77 WVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNY--NSRTHDNDLMLLQLQ 134
Query: 116 LPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGV 175
P R+ +V+P+ + CA+ GT C VSGWG + P +P LQC+N++I C
Sbjct: 135 QPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKA 194
Query: 176 YPGRITSNMVCAGGVP--GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTY 233
YP IT MVCA GVP G+D+CQGDSGGPLVC G LQGLVSWG + C G PGVYT
Sbjct: 195 YPRTITPGMVCA-GVPQGGKDSCQGDSGGPLVCRGQLQGLVSWG-MERCALPGYPGVYTN 252
Query: 234 ICKYVDWIRMIMRN 247
+CKY WI MR+
Sbjct: 253 LCKYRSWIEETMRD 266
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 218 bits (555), Expect = 4e-57
Identities = 111/226 (49%), Positives = 143/226 (63%), Gaps = 5/226 (2%)
Query: 25 GTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTE 84
G C +SQPWQ L L CGGVL+ +WVLTAAHC V LG+H+L +++ E
Sbjct: 39 GYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGE 98
Query: 85 QIRHSGFSVTHPGYLGAST--SHEHDLRLLRLRLPVRVTSSVQPLPLP-NDCATAGTECH 141
Q+R S+ HP Y + T +H+HD+ LL L+ PV++T +Q LPL N+ T GT C
Sbjct: 99 QVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCR 158
Query: 142 VSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVP-GQDACQGDS 200
VSGWG T P+ +P LQC N+ + S C VYPG+IT NM+CAG G+D+C+GDS
Sbjct: 159 VSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDS 218
Query: 201 GGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMR 246
GGPLVC L G+VSWG PCGQ PGVYT + +YV WIR +R
Sbjct: 219 GGPLVCNRTLYGIVSWGDF-PCGQPDRPGVYTRVSRYVLWIRETIR 263
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 216 bits (551), Expect = 1e-56
Identities = 112/240 (46%), Positives = 147/240 (61%), Gaps = 10/240 (4%)
Query: 8 LLCVLGLSQAATP----KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHC 63
L+ VL L AA K+ +G C + S P+Q L+ L CGGVLI WVLTAAHC
Sbjct: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63
Query: 64 SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSS 123
V LG+H+L Q + +++ +V HP Y A SH+ D+ LLRL P +++
Sbjct: 64 KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAA--SHDQDIMLLRLARPAKLSEL 121
Query: 124 VQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSN 183
+QPLPL DC+ T CH+ GWG T FPD +QC + +VS C YPG+IT N
Sbjct: 122 IQPLPLERDCSANTTSCHILGWGKT--ADGDFPDTIQCAYIHLVSREECEHAYPGQITQN 179
Query: 184 MVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIR 242
M+CAG G+D+CQGDSGGPLVCG L+GLVSWG++ PCG PGVYT +C+Y +WI+
Sbjct: 180 MLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNI-PCGSKEKPGVYTNVCRYTNWIQ 238
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 216 bits (551), Expect = 1e-56
Identities = 112/240 (46%), Positives = 147/240 (61%), Gaps = 10/240 (4%)
Query: 8 LLCVLGLSQAATP----KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHC 63
L+ VL L AA K+ +G C + S P+Q L+ L CGGVLI WVLTAAHC
Sbjct: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63
Query: 64 SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSS 123
V LG+H+L Q + +++ +V HP Y A SH+ D+ LLRL P +++
Sbjct: 64 KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAA--SHDQDIMLLRLARPAKLSEL 121
Query: 124 VQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSN 183
+QPLPL DC+ T CH+ GWG T FPD +QC + +VS C YPG+IT N
Sbjct: 122 IQPLPLERDCSANTTSCHILGWGKT--ADGDFPDTIQCAYIHLVSREECEHAYPGQITQN 179
Query: 184 MVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIR 242
M+CAG G+D+CQGDSGGPLVCG L+GLVSWG++ PCG PGVYT +C+Y +WI+
Sbjct: 180 MLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNI-PCGSKEKPGVYTNVCRYTNWIQ 238
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 213 bits (541), Expect = 2e-55
Identities = 115/258 (44%), Positives = 152/258 (58%), Gaps = 16/258 (6%)
Query: 1 MGLSIFLLLCVLGLS--------QAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLI 52
M S+ L L +L LS +A KI +G C R S PWQV L G L CGGVL+
Sbjct: 1 MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
Query: 53 DHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLL 112
+ RWVLTAAHC + Y V LG +L D Q + S HPGY ++ +H +DL L+
Sbjct: 61 NERWVLTAAHCKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGY--STQTHVNDLMLV 116
Query: 113 RLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATC 172
+L R++S V+ + LP+ C GT C VSGWG T P FP L C+++ ++S C
Sbjct: 117 KLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC 176
Query: 173 HGVYPGRITSNMVCAGGVPG--QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGV 230
VY + ++M+CA G+P ++AC GDSGGPLVC G LQGLVSWG+ PCGQ PGV
Sbjct: 177 TKVYKDLLENSMLCA-GIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTF-PCGQPNDPGV 234
Query: 231 YTYICKYVDWIRMIMRNN 248
YT +CK+ WI M+ +
Sbjct: 235 YTQVCKFTKWINDTMKKH 252
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 213 bits (541), Expect = 2e-55
Identities = 115/258 (44%), Positives = 152/258 (58%), Gaps = 16/258 (6%)
Query: 1 MGLSIFLLLCVLGLS--------QAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLI 52
M S+ L L +L LS +A KI +G C R S PWQV L G L CGGVL+
Sbjct: 1 MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
Query: 53 DHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLL 112
+ RWVLTAAHC + Y V LG +L D Q + S HPGY ++ +H +DL L+
Sbjct: 61 NERWVLTAAHCKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGY--STQTHVNDLMLV 116
Query: 113 RLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATC 172
+L R++S V+ + LP+ C GT C VSGWG T P FP L C+++ ++S C
Sbjct: 117 KLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC 176
Query: 173 HGVYPGRITSNMVCAGGVPG--QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGV 230
VY + ++M+CA G+P ++AC GDSGGPLVC G LQGLVSWG+ PCGQ PGV
Sbjct: 177 TKVYKDLLENSMLCA-GIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTF-PCGQPNDPGV 234
Query: 231 YTYICKYVDWIRMIMRNN 248
YT +CK+ WI M+ +
Sbjct: 235 YTQVCKFTKWINDTMKKH 252
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 193 bits (491), Expect = 1e-49
Identities = 106/245 (43%), Positives = 144/245 (58%), Gaps = 10/245 (4%)
Query: 3 LSIFLLLCVLGLSQAAT----PKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVL 58
+++ L+L + + AA KI G C NS P+QV L G CGG LI +WV+
Sbjct: 1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVV 59
Query: 59 TAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPV 118
+A HC SR VRLGEH++ L+ EQ ++ + HP Y S + ++D+ L++L P
Sbjct: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKY--NSRTLDNDILLIKLSSPA 117
Query: 119 RVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPG 178
+ S V + LP AGTE +SGWG T +PD LQCL+ ++S A C YPG
Sbjct: 118 VINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPG 177
Query: 179 RITSNMVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKY 237
+IT+NM C G + G+D+CQGDSGGP+V G LQG+VSWG C Q PGVYT + Y
Sbjct: 178 KITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGY--GCAQKNRPGVYTKVYNY 235
Query: 238 VDWIR 242
VDWI+
Sbjct: 236 VDWIK 240
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 192 bits (487), Expect = 3e-49
Identities = 103/239 (43%), Positives = 144/239 (60%), Gaps = 8/239 (3%)
Query: 6 FLLLCVLG-LSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCS 64
+L+L V G L + +I NG +C +SQPWQ L L C GVL+ +WVL+AAHC
Sbjct: 14 YLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF 73
Query: 65 GSRYWVRLGEHSL-SQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSS 123
+ Y + LG HSL + + Q+ + SV HP Y + +DL L++L V + +
Sbjct: 74 QNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLA--NDLMLIKLDESVSESDT 131
Query: 124 VQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSN 183
++ + + + C TAG C VSGWG+ + R P +LQC+N+S+VS C +Y +
Sbjct: 132 IRSISIASQCPTAGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPS 189
Query: 184 MVCAGGVPGQ-DACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWI 241
M CAGG Q D+C GDSGGPL+C G LQGLVS+G PCGQ G+PGVYT +CK+ +WI
Sbjct: 190 MFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGK-APCGQVGVPGVYTNLCKFTEWI 247
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 191 bits (485), Expect = 5e-49
Identities = 100/229 (43%), Positives = 135/229 (58%), Gaps = 6/229 (2%)
Query: 21 KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQL 80
KI G C NS P+QV L G CGG LI+ +WV++A HC SR VRLGEH++ L
Sbjct: 23 KIVGGYNCEENSVPYQVSLNSGYHF-CGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVL 81
Query: 81 DWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGTEC 140
+ EQ ++ + HP Y + ++ D+ L++L + + V + LP GT+C
Sbjct: 82 EGNEQFINAAKIIRHPQYDRKTLNN--DIMLIKLSSRAVINARVSTISLPTAPPATGTKC 139
Query: 141 HVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVP-GQDACQGD 199
+SGWG T +PD LQCL+ ++S A C YPG+ITSNM C G + G+D+CQGD
Sbjct: 140 LISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGD 199
Query: 200 SGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN 248
SGGP+VC G LQG+VSWG C Q PGVYT + YV WI+ + N
Sbjct: 200 SGGPVVCNGQLQGVVSWGD--GCAQKNKPGVYTKVYNYVKWIKNTIAAN 246
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 190 bits (483), Expect = 9e-49
Identities = 102/242 (42%), Positives = 143/242 (59%), Gaps = 10/242 (4%)
Query: 6 FLLLCVLGLSQAAT----PKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAA 61
FL+L +G + A KI G C NS P+QV L G+ CGG LI +WV++AA
Sbjct: 4 FLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAA 62
Query: 62 HCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVT 121
HC +R VRLGEH++ L+ EQ ++ + HP Y + ++D+ L++L P +
Sbjct: 63 HCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKY--NRDTLDNDIMLIKLSSPAVIN 120
Query: 122 SSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRIT 181
+ V + LP AGTEC +SGWG T +PD L+CL+ +++ A C YPG+IT
Sbjct: 121 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 180
Query: 182 SNMVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDW 240
++M C G + G+D+CQ DSGGP+VC G LQG+VSWG C PGVYT + YVDW
Sbjct: 181 NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH--GCAWKNRPGVYTKVYNYVDW 238
Query: 241 IR 242
I+
Sbjct: 239 IK 240
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 189 bits (479), Expect = 3e-48
Identities = 105/260 (40%), Positives = 143/260 (55%), Gaps = 18/260 (6%)
Query: 6 FLLLCV---LGLSQAATP---KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLT 59
FL+LC+ LG + AA P +I G EC ++SQPWQ L+ ++ +CGG+L+ +WVLT
Sbjct: 3 FLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLT 62
Query: 60 AAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGY---------LGASTSHEHDLR 110
AAHC Y + LG H+L + T Q H S HPG+ A + HDL
Sbjct: 63 AAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLM 122
Query: 111 LLRLRLPV-RVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSH 169
LLRL P +T +V+ + LP + G+ C SGWG FPD LQC++L I+ +
Sbjct: 123 LLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPN 182
Query: 170 ATCHGVYPGRITSNMVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIP 228
C + ++T M+C G + G+D C GDSGGPL+C GVLQG+ SWG V PCG P
Sbjct: 183 DECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYV-PCGTPNKP 241
Query: 229 GVYTYICKYVDWIRMIMRNN 248
V + YV WI + N
Sbjct: 242 SVAVRVLSYVKWIEDTIAEN 261
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 187 bits (476), Expect = 6e-48
Identities = 97/223 (43%), Positives = 135/223 (60%), Gaps = 6/223 (2%)
Query: 21 KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQL 80
KI G C NS P+QV L G+ CGG LI +WV++AAHC +R VRLGEH++ L
Sbjct: 80 KIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVL 138
Query: 81 DWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGTEC 140
+ EQ ++ + HP Y + ++D+ L++L P + + V + LP AGTEC
Sbjct: 139 EGNEQFINAAKIIRHPKY--NRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTEC 196
Query: 141 HVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVP-GQDACQGD 199
+SGWG T +PD L+CL+ +++ A C YPG+IT++M C G + G+D+CQ D
Sbjct: 197 LISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRD 256
Query: 200 SGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIR 242
SGGP+VC G LQG+VSWG C PGVYT + YVDWI+
Sbjct: 257 SGGPVVCNGQLQGVVSWGH--GCAWKNRPGVYTKVYNYVDWIK 297
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 181 bits (460), Expect = 4e-46
Identities = 101/250 (40%), Positives = 134/250 (53%), Gaps = 13/250 (5%)
Query: 5 IFLLLCV--LGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
+FL L V +G + +I G EC ++SQPWQV + CGGVL+ +WVLTAAH
Sbjct: 6 VFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65
Query: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGY---------LGASTSHEHDLRLLR 113
C ++ + LG HSL + T Q+ S HP Y L HDL LLR
Sbjct: 66 CIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLR 125
Query: 114 LRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH 173
L P +T +V+ + LP GT C+ SGWG P LQC++L ++S+ C
Sbjct: 126 LSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA 185
Query: 174 GVYPGRITSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYT 232
V+P ++T M+CAG G+ C GDSGGPLVC GVLQG+ SWGS PC P +YT
Sbjct: 186 QVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGS-EPCALPERPSLYT 244
Query: 233 YICKYVDWIR 242
+ Y WI+
Sbjct: 245 KVVHYRKWIK 254
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 177 bits (450), Expect = 6e-45
Identities = 102/250 (40%), Positives = 131/250 (52%), Gaps = 11/250 (4%)
Query: 3 LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
LSI L + G +I G EC ++SQPWQV ++ CGGVL+ +WVLTAAH
Sbjct: 6 LSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAH 65
Query: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHE---------HDLRLLR 113
C V LG H+L + + T Q S HP Y + H+ HDL LLR
Sbjct: 66 CLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLR 125
Query: 114 LRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH 173
L P ++T V+ L LP GT C+ SGWG P LQC++L ++S+ C
Sbjct: 126 LSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA 185
Query: 174 GVYPGRITSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYT 232
Y ++T M+CAG G+D C GDSGGPLVC GVLQG+ SWG PC P VYT
Sbjct: 186 RAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGP-EPCALPEKPAVYT 244
Query: 233 YICKYVDWIR 242
+ Y WI+
Sbjct: 245 KVVHYRKWIK 254
>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
sapiens]
Length = 218
Score = 157 bits (398), Expect = 6e-39
Identities = 91/241 (37%), Positives = 120/241 (49%), Gaps = 38/241 (15%)
Query: 5 IFLLLCV--LGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
+FL L V +G + +I G EC ++SQPWQV + CGGVL+ +WVLTAAH
Sbjct: 6 VFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65
Query: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTS 122
C + PG HDL LLRL P +T
Sbjct: 66 C-----------------------------IRKPG-----DDSSHDLMLLRLSEPAELTD 91
Query: 123 SVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITS 182
+V+ + LP GT C+ SGWG P LQC++L ++S+ C V+P ++T
Sbjct: 92 AVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK 151
Query: 183 NMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWI 241
M+CAG G+ C GDSGGPLVC GVLQG+ SWGS PC P +YT + Y WI
Sbjct: 152 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGS-EPCALPERPSLYTKVVHYRKWI 210
Query: 242 R 242
+
Sbjct: 211 K 211
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.475
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,350,961
Number of Sequences: 37866
Number of extensions: 564559
Number of successful extensions: 2729
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 1509
Number of HSP's gapped (non-prelim): 779
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.