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Search of human proteins with 22208982
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
(276 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 579 e-166
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 579 e-166
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 579 e-166
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 219 3e-57
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 214 7e-56
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 213 1e-55
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 213 1e-55
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 213 1e-55
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 202 3e-52
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 201 4e-52
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 197 1e-50
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 196 2e-50
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 196 2e-50
gi|11496281 kallikrein 13 precursor [Homo sapiens] 196 2e-50
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 195 3e-50
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 193 2e-49
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 186 2e-47
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 186 2e-47
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 185 4e-47
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 185 4e-47
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 185 4e-47
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 182 3e-46
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 179 2e-45
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 179 2e-45
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 177 7e-45
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 161 5e-40
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 159 2e-39
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 152 2e-37
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 147 8e-36
gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 140 1e-33
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 579 bits (1493), Expect = e-166
Identities = 276/276 (100%), Positives = 276/276 (100%)
Query: 1 MRAPHLHLSAASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQ 60
MRAPHLHLSAASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQ
Sbjct: 1 MRAPHLHLSAASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQ 60
Query: 61 VSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPK 120
VSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPK
Sbjct: 61 VSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPK 120
Query: 121 YHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAAR 180
YHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAAR
Sbjct: 121 YHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAAR 180
Query: 181 RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQ 240
RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQ
Sbjct: 181 RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQ 240
Query: 241 GILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
GILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN
Sbjct: 241 GILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 579 bits (1493), Expect = e-166
Identities = 276/276 (100%), Positives = 276/276 (100%)
Query: 1 MRAPHLHLSAASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQ 60
MRAPHLHLSAASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQ
Sbjct: 1 MRAPHLHLSAASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQ 60
Query: 61 VSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPK 120
VSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPK
Sbjct: 61 VSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPK 120
Query: 121 YHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAAR 180
YHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAAR
Sbjct: 121 YHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAAR 180
Query: 181 RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQ 240
RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQ
Sbjct: 181 RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQ 240
Query: 241 GILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
GILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN
Sbjct: 241 GILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 579 bits (1493), Expect = e-166
Identities = 276/276 (100%), Positives = 276/276 (100%)
Query: 1 MRAPHLHLSAASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQ 60
MRAPHLHLSAASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQ
Sbjct: 1 MRAPHLHLSAASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQ 60
Query: 61 VSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPK 120
VSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPK
Sbjct: 61 VSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPK 120
Query: 121 YHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAAR 180
YHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAAR
Sbjct: 121 YHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAAR 180
Query: 181 RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQ 240
RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQ
Sbjct: 181 RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQ 240
Query: 241 GILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
GILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN
Sbjct: 241 GILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 219 bits (557), Expect = 3e-57
Identities = 112/230 (48%), Positives = 138/230 (60%), Gaps = 8/230 (3%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
G+ C R SQPWQV LF G S C GVL+D WVLTAAHC W R+G+ L L E
Sbjct: 25 GTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTE 84
Query: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Q+R + SV HP Y S + EHDL LL+L PV + V+ L LP CA G
Sbjct: 85 QIRHSGFSVTHPGYLGAS------TSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGT 138
Query: 168 QCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQS 227
+C V+GWG T R + L C +++I+S C YPG +T+NM+CAG GQD CQ
Sbjct: 139 ECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVPGQDACQG 198
Query: 228 DSGGPLVCDETLQGILSWG-VYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
DSGGPLVC LQG++SWG V PCG P VYT ICKY+ WI ++R+N
Sbjct: 199 DSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN 248
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 214 bits (545), Expect = 7e-56
Identities = 112/254 (44%), Positives = 139/254 (54%), Gaps = 12/254 (4%)
Query: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
LL+ WA + Q D L G C SQPWQ +LF G C GVLV +WVL
Sbjct: 16 LLLGGAWAGHSRA--QEDKVLG----GHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVL 69
Query: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
TAAHC R+GD L G EQ +S+ HP Y+ HDLMLL
Sbjct: 70 TAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDV-----EDHNHDLMLL 124
Query: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
+L LG +V+ + L C QPG +C V+GWGT + R + L C+ + I K+C
Sbjct: 125 QLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKC 184
Query: 202 EVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQ 261
E YPG +T+ M+CAG +G D CQ DSGGPLVCD LQGI SWG PCG + P VYT
Sbjct: 185 EDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTN 244
Query: 262 ICKYMSWINKVIRS 275
IC+Y+ WI K+I S
Sbjct: 245 ICRYLDWIKKIIGS 258
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 213 bits (542), Expect = 1e-55
Identities = 108/264 (40%), Positives = 154/264 (58%), Gaps = 14/264 (5%)
Query: 14 ARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAG 73
AR+L L +L+ L A Q D +D G+PCARGS PWQV+L +G HC G
Sbjct: 2 ARSLLLPLQILLLSLALETAGEEAQGDKIID----GAPCARGSHPWQVALLSGNQLHCGG 57
Query: 74 VLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGPILPRRT 133
VLV++ WVLTAAHC +G D L + ++++ ++S HP Y +T
Sbjct: 58 VLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIK-ASKSFRHPGYST--------QT 108
Query: 134 DEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSI 193
+DLML+KL L V+ ++LP RC PG C V+GWGTT + V + L C +
Sbjct: 109 HVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDV 168
Query: 194 TILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGS 252
++SP++C Y ++ N+M+CAG+ D ++ C DSGGPLVC TLQG++SWG +PCG
Sbjct: 169 KLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQ 228
Query: 253 AQHPAVYTQICKYMSWINKVIRSN 276
P VYTQ+CK+ WIN ++ +
Sbjct: 229 PNDPGVYTQVCKFTKWINDTMKKH 252
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 213 bits (542), Expect = 1e-55
Identities = 108/264 (40%), Positives = 154/264 (58%), Gaps = 14/264 (5%)
Query: 14 ARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAG 73
AR+L L +L+ L A Q D +D G+PCARGS PWQV+L +G HC G
Sbjct: 2 ARSLLLPLQILLLSLALETAGEEAQGDKIID----GAPCARGSHPWQVALLSGNQLHCGG 57
Query: 74 VLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGPILPRRT 133
VLV++ WVLTAAHC +G D L + ++++ ++S HP Y +T
Sbjct: 58 VLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIK-ASKSFRHPGYST--------QT 108
Query: 134 DEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSI 193
+DLML+KL L V+ ++LP RC PG C V+GWGTT + V + L C +
Sbjct: 109 HVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDV 168
Query: 194 TILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGS 252
++SP++C Y ++ N+M+CAG+ D ++ C DSGGPLVC TLQG++SWG +PCG
Sbjct: 169 KLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQ 228
Query: 253 AQHPAVYTQICKYMSWINKVIRSN 276
P VYTQ+CK+ WIN ++ +
Sbjct: 229 PNDPGVYTQVCKFTKWINDTMKKH 252
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 213 bits (542), Expect = 1e-55
Identities = 105/228 (46%), Positives = 130/228 (57%), Gaps = 6/228 (2%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
G C SQPWQ +LF G C GVLV +WVLTAAHC R+GD L G E
Sbjct: 81 GHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPE 140
Query: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Q +S+ HP Y+ HDLMLL+L LG +V+ + L C QPG
Sbjct: 141 QEIPVVQSIPHPCYNSSDV-----EDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQ 195
Query: 168 QCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQS 227
+C V+GWGT + R + L C+ + I K+CE YPG +T+ M+CAG +G D CQ
Sbjct: 196 KCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQG 255
Query: 228 DSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRS 275
DSGGPLVCD LQGI SWG PCG + P VYT IC+Y+ WI K+I S
Sbjct: 256 DSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 202 bits (514), Expect = 3e-52
Identities = 106/217 (48%), Positives = 128/217 (58%), Gaps = 8/217 (3%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
G+ C R SQPWQV LF G S C GVL+D WVLTAAHC W R+G+ L L E
Sbjct: 25 GTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTE 84
Query: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Q+R + SV HP Y S + EHDL LL+L PV + V+ L LP CA G
Sbjct: 85 QIRHSGFSVTHPGYLGAS------TSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGT 138
Query: 168 QCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQS 227
+C V+GWG T R + L C +++I+S C YPG +T+NM+CAG GQD CQ
Sbjct: 139 ECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVPGQDACQG 198
Query: 228 DSGGPLVCDETLQGILSWG-VYPCGSAQHPAVYTQIC 263
DSGGPLVC LQG++SWG V PCG P VYT IC
Sbjct: 199 DSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYIC 235
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 201 bits (512), Expect = 4e-52
Identities = 100/240 (41%), Positives = 142/240 (59%), Gaps = 20/240 (8%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
G CA SQPWQV+L+ F+C L+ WVL+AAHC ++ + R+G+ +L G E
Sbjct: 25 GDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRKRDGPE 84
Query: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
QLR T+R + HP+Y R+ +D+MLL+L +P L P+VR LP RC PG+
Sbjct: 85 QLRTTSRVIPHPRYEA--------RSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGE 136
Query: 168 QCQVAGWGTTAAR----------RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG 217
C V+GWG + +V L C++I+I+S C+ YPG +TN M+CAG
Sbjct: 137 ACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAG 196
Query: 218 LD-RGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
+ RG + C+ DSGGPLVC LQGI+SWG PC + P VYT++C Y+ WI + ++ N
Sbjct: 197 AEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 197 bits (500), Expect = 1e-50
Identities = 102/266 (38%), Positives = 153/266 (57%), Gaps = 9/266 (3%)
Query: 13 GARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCA 72
GAR+ ++ + A A L +TR+ G C SQPWQ +LF C
Sbjct: 24 GARSSPLQAMRILQLILLALATGLVGGETRI---IKGFECKPHSQPWQAALFEKTRLLCG 80
Query: 73 GVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPR 131
L+ W+LTAAHC +G +L +G EQ R T S HP ++ LP
Sbjct: 81 ATLIAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNS----LPN 136
Query: 132 RTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCS 191
+ +D+ML+K+A PV + VR L L RC G C ++GWG+T++ +++ L C+
Sbjct: 137 KDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCA 196
Query: 192 SITILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPC 250
+ITI+ ++CE YPG +T+ M+CA + + G+D CQ DSGGPLVC+++LQGI+SWG PC
Sbjct: 197 NITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPC 256
Query: 251 GSAQHPAVYTQICKYMSWINKVIRSN 276
+ P VYT++CKY+ WI + +++N
Sbjct: 257 AITRKPGVYTKVCKYVDWIQETMKNN 282
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 196 bits (498), Expect = 2e-50
Identities = 94/230 (40%), Positives = 139/230 (60%), Gaps = 6/230 (2%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
G C SQPWQ +LF C L+ W+LTAAHC +G +L +G E
Sbjct: 25 GFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCE 84
Query: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Q R T S HP ++ LP + +D+ML+K+A PV + VR L L RC G
Sbjct: 85 QTRTATESFPHPGFNNS----LPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGT 140
Query: 168 QCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQ 226
C ++GWG+T++ +++ L C++ITI+ ++CE YPG +T+ M+CA + + G+D CQ
Sbjct: 141 SCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQ 200
Query: 227 SDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
DSGGPLVC+++LQGI+SWG PC + P VYT++CKY+ WI + +++N
Sbjct: 201 GDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 250
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 196 bits (498), Expect = 2e-50
Identities = 94/230 (40%), Positives = 139/230 (60%), Gaps = 6/230 (2%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
G C SQPWQ +LF C L+ W+LTAAHC +G +L +G E
Sbjct: 25 GFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCE 84
Query: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Q R T S HP ++ LP + +D+ML+K+A PV + VR L L RC G
Sbjct: 85 QTRTATESFPHPGFNNS----LPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGT 140
Query: 168 QCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQ 226
C ++GWG+T++ +++ L C++ITI+ ++CE YPG +T+ M+CA + + G+D CQ
Sbjct: 141 SCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQ 200
Query: 227 SDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
DSGGPLVC+++LQGI+SWG PC + P VYT++CKY+ WI + +++N
Sbjct: 201 GDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 250
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 196 bits (497), Expect = 2e-50
Identities = 100/229 (43%), Positives = 138/229 (60%), Gaps = 7/229 (3%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ-GE 107
G C SQPWQ +L C GVLV WVLTAAHC + L +G L ++ GE
Sbjct: 39 GYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGE 98
Query: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCA-QPG 166
Q+R S+ HP+Y + + +HD+MLL+L PV L ++ L L + PG
Sbjct: 99 QVREVVHSIPHPEYRRSPTHL----NHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPG 154
Query: 167 DQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGL-DRGQDPC 225
C+V+GWGTT + +V Y K L C++I + S +EC YPG +T+NM+CAG + G+D C
Sbjct: 155 TTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSC 214
Query: 226 QSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 274
+ DSGGPLVC+ TL GI+SWG +PCG P VYT++ +Y+ WI + IR
Sbjct: 215 EGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 195 bits (496), Expect = 3e-50
Identities = 97/230 (42%), Positives = 134/230 (58%), Gaps = 12/230 (5%)
Query: 49 GSPCARGSQPWQVSLFNG--LSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG 106
G C R SQPWQ +L G F C G L+ WV+TAAHCG L +G +L +
Sbjct: 44 GHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEA 103
Query: 107 -EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQP 165
+Q+ R R V HP Y+ RT ++DLMLL+L +P +G VR +++ CA P
Sbjct: 104 TQQVLRVVRQVTHPNYNS--------RTHDNDLMLLQLQQPARIGRAVRPIEVTQACASP 155
Query: 166 GDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDR-GQDP 224
G C+V+GWGT ++ +Y L C +I I + C+ YP +T M+CAG+ + G+D
Sbjct: 156 GTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDS 215
Query: 225 CQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 274
CQ DSGGPLVC LQG++SWG+ C +P VYT +CKY SWI + +R
Sbjct: 216 CQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMR 265
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 193 bits (490), Expect = 2e-49
Identities = 102/262 (38%), Positives = 142/262 (54%), Gaps = 20/262 (7%)
Query: 17 LAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSP-CARGSQPWQVSLFNGLSFHCAGVL 75
L LL LL WA D A G+ C SQPWQ LF+ C L
Sbjct: 6 LCALLSLLAGHGWA-------------DTRAIGAEECRPNSQPWQAGLFHLTRLFCGATL 52
Query: 76 VDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTD 134
+ W+LTAAHC LW R+G+ HL +G EQL R T HP +++ L
Sbjct: 53 ISDRWLLTAAHCRKPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKD----LSANDH 108
Query: 135 EHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSIT 194
D+ML++L R L P V+ L L C PG QC ++GWG ++ + + L C++I+
Sbjct: 109 NDDIMLIRLPRQARLSPAVQPLNLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANIS 168
Query: 195 ILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSA 253
IL K C YPG ++++M+CAGL + G+ CQ DSGGPLVC+ TL G++S G PC
Sbjct: 169 ILENKLCHWAYPGHISDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRP 228
Query: 254 QHPAVYTQICKYMSWINKVIRS 275
+ PAVYT +C Y+ WI +++ +
Sbjct: 229 RRPAVYTSVCHYLDWIQEIMEN 250
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 186 bits (472), Expect = 2e-47
Identities = 99/254 (38%), Positives = 141/254 (55%), Gaps = 22/254 (8%)
Query: 24 LMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLT 83
L+A WA E L +G PC + S P+Q +L+ C GVL+ WVLT
Sbjct: 10 LIAAAWAEEQNKL----------VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLT 59
Query: 84 AAHCGNKPLWARVGDDHLLLLQGEQLRRTT-RSVVHPKYHQGSGPILPRRTDEHDLMLLK 142
AAHC L +G +L + Q + + R+V+HP Y S + D+MLL+
Sbjct: 60 AAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAAS--------HDQDIMLLR 111
Query: 143 LARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECE 202
LARP L ++ L L C+ C + GWG TA + + C+ I ++S +ECE
Sbjct: 112 LARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECE 169
Query: 203 VFYPGVVTNNMICAGLDR-GQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQ 261
YPG +T NM+CAG ++ G+D CQ DSGGPLVC + L+G++SWG PCGS + P VYT
Sbjct: 170 HAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTN 229
Query: 262 ICKYMSWINKVIRS 275
+C+Y +WI K I++
Sbjct: 230 VCRYTNWIQKTIQA 243
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 186 bits (472), Expect = 2e-47
Identities = 99/254 (38%), Positives = 141/254 (55%), Gaps = 22/254 (8%)
Query: 24 LMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLT 83
L+A WA E L +G PC + S P+Q +L+ C GVL+ WVLT
Sbjct: 10 LIAAAWAEEQNKL----------VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLT 59
Query: 84 AAHCGNKPLWARVGDDHLLLLQGEQLRRTT-RSVVHPKYHQGSGPILPRRTDEHDLMLLK 142
AAHC L +G +L + Q + + R+V+HP Y S + D+MLL+
Sbjct: 60 AAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAAS--------HDQDIMLLR 111
Query: 143 LARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECE 202
LARP L ++ L L C+ C + GWG TA + + C+ I ++S +ECE
Sbjct: 112 LARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECE 169
Query: 203 VFYPGVVTNNMICAGLDR-GQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQ 261
YPG +T NM+CAG ++ G+D CQ DSGGPLVC + L+G++SWG PCGS + P VYT
Sbjct: 170 HAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTN 229
Query: 262 ICKYMSWINKVIRS 275
+C+Y +WI K I++
Sbjct: 230 VCRYTNWIQKTIQA 243
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 185 bits (469), Expect = 4e-47
Identities = 95/232 (40%), Positives = 132/232 (56%), Gaps = 13/232 (5%)
Query: 49 GSPCARGSQPWQVSLF-NGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHL--LLLQ 105
GS C +QPWQ +L +C VLV W+LTAAHC K R+G L +
Sbjct: 70 GSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYES 129
Query: 106 GEQLRRTTRSVVHPKY-HQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 164
G+Q+ + +S+ HP Y H G +DLML+KL R + VR + + C
Sbjct: 130 GQQMFQGVKSIPHPGYSHPGHS---------NDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
Query: 165 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDP 224
G +C V+GWGTT + +V + K L C +I++LS K CE YP + + M CAG G+D
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240
Query: 225 CQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
CQ DSGGP+VC+ +LQG++SWG YPC P VYT +CK+ WI + I++N
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 185 bits (469), Expect = 4e-47
Identities = 95/232 (40%), Positives = 132/232 (56%), Gaps = 13/232 (5%)
Query: 49 GSPCARGSQPWQVSLF-NGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHL--LLLQ 105
GS C +QPWQ +L +C VLV W+LTAAHC K R+G L +
Sbjct: 70 GSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYES 129
Query: 106 GEQLRRTTRSVVHPKY-HQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 164
G+Q+ + +S+ HP Y H G +DLML+KL R + VR + + C
Sbjct: 130 GQQMFQGVKSIPHPGYSHPGHS---------NDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
Query: 165 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDP 224
G +C V+GWGTT + +V + K L C +I++LS K CE YP + + M CAG G+D
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240
Query: 225 CQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
CQ DSGGP+VC+ +LQG++SWG YPC P VYT +CK+ WI + I++N
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 185 bits (469), Expect = 4e-47
Identities = 95/232 (40%), Positives = 132/232 (56%), Gaps = 13/232 (5%)
Query: 49 GSPCARGSQPWQVSLF-NGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHL--LLLQ 105
GS C +QPWQ +L +C VLV W+LTAAHC K R+G L +
Sbjct: 70 GSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYES 129
Query: 106 GEQLRRTTRSVVHPKY-HQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 164
G+Q+ + +S+ HP Y H G +DLML+KL R + VR + + C
Sbjct: 130 GQQMFQGVKSIPHPGYSHPGHS---------NDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
Query: 165 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDP 224
G +C V+GWGTT + +V + K L C +I++LS K CE YP + + M CAG G+D
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240
Query: 225 CQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
CQ DSGGP+VC+ +LQG++SWG YPC P VYT +CK+ WI + I++N
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 182 bits (462), Expect = 3e-46
Identities = 99/256 (38%), Positives = 141/256 (55%), Gaps = 14/256 (5%)
Query: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
LL+ + A A P +D D G C S P+QVSL +G F C G L+ + WV+
Sbjct: 3 LLLILTFVAAAVAAPFDDD--DKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVV 59
Query: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
+A HC + R+G+ ++ +L+G EQ + + HPKY+ RT ++D++L+
Sbjct: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNS--------RTLDNDILLI 111
Query: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
KL+ P V+ RV A+ LP G + ++GWG T + Y L C +LS EC
Sbjct: 112 KLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAEC 171
Query: 202 EVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYT 260
E YPG +TNNM C G L+ G+D CQ DSGGP+V + LQGI+SWG Y C P VYT
Sbjct: 172 EASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYT 230
Query: 261 QICKYMSWINKVIRSN 276
++ Y+ WI I +N
Sbjct: 231 KVYNYVDWIKDTIAAN 246
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 179 bits (454), Expect = 2e-45
Identities = 99/270 (36%), Positives = 146/270 (54%), Gaps = 24/270 (8%)
Query: 19 KLLPLLMAQLWAAE----------AALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLS 68
+L PLL + W A +P +D D G C S P+QVSL +G
Sbjct: 46 ELHPLLGGRTWRAARDADGCEALGTVAVPFDDD--DKIVGGYTCEENSLPYQVSLNSGSH 103
Query: 69 FHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGP 127
F C G L+ + WV++AAHC + R+G+ ++ +L+G EQ + + HPKY+
Sbjct: 104 F-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYN----- 157
Query: 128 ILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKG 187
R T ++D+ML+KL+ P V+ RV + LP G +C ++GWG T + Y
Sbjct: 158 ---RDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDE 214
Query: 188 LTCSSITILSPKECEVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWG 246
L C +L+ EC+ YPG +TN+M C G L+ G+D CQ DSGGP+VC+ LQG++SWG
Sbjct: 215 LKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG 274
Query: 247 VYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
+ C P VYT++ Y+ WI I +N
Sbjct: 275 -HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 179 bits (454), Expect = 2e-45
Identities = 96/256 (37%), Positives = 144/256 (56%), Gaps = 16/256 (6%)
Query: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
L++A + AA A +D + G C S P+QVSL +G F C G L+ + WV+
Sbjct: 5 LILAFVGAAVAVPFDDDDKIVG----GYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVV 59
Query: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
+AAHC + R+G+ ++ +L+G EQ + + HPKY+ R T ++D+ML+
Sbjct: 60 SAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYN--------RDTLDNDIMLI 111
Query: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
KL+ P V+ RV + LP G +C ++GWG T + Y L C +L+ EC
Sbjct: 112 KLSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAEC 171
Query: 202 EVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYT 260
+ YPG +TN+M C G L+ G+D CQ DSGGP+VC+ LQG++SWG + C P VYT
Sbjct: 172 KASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYT 230
Query: 261 QICKYMSWINKVIRSN 276
++ Y+ WI I +N
Sbjct: 231 KVYNYVDWIKDTIAAN 246
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 177 bits (450), Expect = 7e-45
Identities = 96/257 (37%), Positives = 142/257 (55%), Gaps = 15/257 (5%)
Query: 22 PLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWV 81
PLL+ AA A +D ++ G C S P+QVSL +G F C G L+++ WV
Sbjct: 3 PLLILTFVAAALAAPFDDDDKI---VGGYNCEENSVPYQVSLNSGYHF-CGGSLINEQWV 58
Query: 82 LTAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLML 140
++A HC + R+G+ ++ +L+G EQ + + HP+Y R+T +D+ML
Sbjct: 59 VSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYD--------RKTLNNDIML 110
Query: 141 LKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKE 200
+KL+ V+ RV + LP G +C ++GWG TA+ Y L C +LS +
Sbjct: 111 IKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAK 170
Query: 201 CEVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVY 259
CE YPG +T+NM C G L+ G+D CQ DSGGP+VC+ LQG++SWG C P VY
Sbjct: 171 CEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVY 229
Query: 260 TQICKYMSWINKVIRSN 276
T++ Y+ WI I +N
Sbjct: 230 TKVYNYVKWIKNTIAAN 246
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 161 bits (408), Expect = 5e-40
Identities = 94/233 (40%), Positives = 121/233 (51%), Gaps = 5/233 (2%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQ 108
G C + SQPWQV++++ HC GVLV WVLTAAHC K +G +L +
Sbjct: 28 GWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTG 87
Query: 109 LR-RTTRSVVHPKYHQGSGPILPRRTDE---HDLMLLKLARPVVLGPRVRALQLPYRCAQ 164
R + S HP Y+ R DE HDLMLL+L+ P + V+ L LP +
Sbjct: 88 QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPA 147
Query: 165 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGL-DRGQD 223
G C +GWG+ + L C S+ +LS C Y VT M+CAGL G+D
Sbjct: 148 LGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKD 207
Query: 224 PCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
C DSGGPLVC+ LQGI SWG PC + PAVYT++ Y WI I +N
Sbjct: 208 TCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 159 bits (403), Expect = 2e-39
Identities = 88/238 (36%), Positives = 123/238 (51%), Gaps = 14/238 (5%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHC--GNKPLWA---RVGDDHLLL 103
G C + SQPWQ +L++ +F C G+LV + WVLTAAHC N LW + DD
Sbjct: 28 GWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDE--- 84
Query: 104 LQGEQLRRTTRSVVHPKYHQGSGPILPRRTDE---HDLMLLKLARPV-VLGPRVRALQLP 159
Q + S HP ++ R+ DE HDLMLL+L P + V+ ++LP
Sbjct: 85 -NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELP 143
Query: 160 YRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-L 218
+ G C +GWG+ + L C + IL EC+ + VT+ M+C G L
Sbjct: 144 TEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHL 203
Query: 219 DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
+ G+D C DSGGPL+CD LQG+ SWG PCG+ P+V ++ Y+ WI I N
Sbjct: 204 EGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAEN 261
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 152 bits (385), Expect = 2e-37
Identities = 85/231 (36%), Positives = 125/231 (54%), Gaps = 13/231 (5%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ--G 106
G C+ SQPWQ +L C+GVLV WVL+AAHC +G L Q G
Sbjct: 34 GEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPG 93
Query: 107 EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPG 166
Q+ + SV HP+Y++ P+L +DLML+KL V +R++ + +C G
Sbjct: 94 SQMVEASLSVRHPEYNR---PLLA-----NDLMLIKLDESVSESDTIRSISIASQCPTAG 145
Query: 167 DQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQ-DPC 225
+ C V+GWG A R+ L C +++++S + C Y + +M CAG Q D C
Sbjct: 146 NSCLVSGWGLLANGRMP--TVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203
Query: 226 QSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
DSGGPL+C+ LQG++S+G PCG P VYT +CK+ WI K ++++
Sbjct: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 147 bits (372), Expect = 8e-36
Identities = 85/233 (36%), Positives = 115/233 (49%), Gaps = 5/233 (2%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGE- 107
G C + SQPWQV + + C GVLV WVLTAAHC +G L +
Sbjct: 28 GWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTG 87
Query: 108 QLRRTTRSVVHPKYHQG---SGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 164
Q+ + + S HP Y + + P HDLMLL+L+ P L V+ + LP +
Sbjct: 88 QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPA 147
Query: 165 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGL-DRGQD 223
G C +GWG+ K L C + ++S C +P VT M+CAG G+
Sbjct: 148 LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKS 207
Query: 224 PCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
C DSGGPLVC+ LQGI SWG PC + P++YT++ Y WI I +N
Sbjct: 208 TCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260
>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
sapiens]
Length = 218
Score = 140 bits (353), Expect = 1e-33
Identities = 82/229 (35%), Positives = 105/229 (45%), Gaps = 40/229 (17%)
Query: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQ 108
G C + SQPWQV + + C GVLV WVLTAAHC KP GDD
Sbjct: 28 GWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRKP-----GDD--------- 73
Query: 109 LRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQ 168
HDLMLL+L+ P L V+ + LP + G
Sbjct: 74 -------------------------SSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTT 108
Query: 169 CQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQS 227
C +GWG+ K L C + ++S C +P VT M+CAG G+ C
Sbjct: 109 CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 168
Query: 228 DSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
DSGGPLVC+ LQGI SWG PC + P++YT++ Y WI I +N
Sbjct: 169 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 217
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,946,716
Number of Sequences: 37866
Number of extensions: 574779
Number of successful extensions: 1650
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1057
Number of HSP's gapped (non-prelim): 196
length of query: 276
length of database: 18,247,518
effective HSP length: 101
effective length of query: 175
effective length of database: 14,423,052
effective search space: 2524034100
effective search space used: 2524034100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.