Search of human proteins with 11527402

Search of human proteins with 11527402

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11527402 integral membrane protein 2B [Homo sapiens]
         (266 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11527402 integral membrane protein 2B [Homo sapiens]               547   e-156
gi|13569885 integral membrane protein 2C isoform 1 [Homo sapiens]     223   1e-58
gi|60302912 integral membrane protein 2C isoform 3 [Homo sapiens]     203   1e-52
gi|4758224 integral membrane protein 2A [Homo sapiens]                201   4e-52
gi|60302914 integral membrane protein 2C isoform 2 [Homo sapiens]     152   2e-37
gi|226246591 phosphodiesterase 2A isoform 3 [Homo sapiens]             30   2.9  
gi|219802706 phosphodiesterase 2A isoform 2 [Homo sapiens]             30   2.9  
gi|4505657 phosphodiesterase 2A isoform 1 [Homo sapiens]               30   2.9  
gi|239735596 transmembrane protein 171 isoform 1 [Homo sapiens]        28   6.4  
gi|239735594 transmembrane protein 171 isoform 2 [Homo sapiens]        28   6.4  
gi|56549683 small CTD phosphatase 3 isoform 1 [Homo sapiens]           28   8.3  

>gi|11527402 integral membrane protein 2B [Homo sapiens]
          Length = 266

 Score =  547 bits (1409), Expect = e-156
 Identities = 266/266 (100%), Positives = 266/266 (100%)

Query: 1   MVKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRAWCWCMCFG 60
           MVKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRAWCWCMCFG
Sbjct: 1   MVKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRAWCWCMCFG 60

Query: 61  LAFMLAGVILGGAYLYKYFALQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIK 120
           LAFMLAGVILGGAYLYKYFALQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIK
Sbjct: 61  LAFMLAGVILGGAYLYKYFALQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIK 120

Query: 121 IFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNL 180
           IFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNL
Sbjct: 121 IFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNL 180

Query: 181 LELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGI 240
           LELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGI
Sbjct: 181 LELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGI 240

Query: 241 QKREASNCFAIRHFENKFAVETLICS 266
           QKREASNCFAIRHFENKFAVETLICS
Sbjct: 241 QKREASNCFAIRHFENKFAVETLICS 266


>gi|13569885 integral membrane protein 2C isoform 1 [Homo sapiens]
          Length = 267

 Score =  223 bits (569), Expect = 1e-58
 Identities = 120/276 (43%), Positives = 166/276 (60%), Gaps = 23/276 (8%)

Query: 1   MVKVTFNSALA--------QKEAKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRA 52
           MVK++F  A+A        +  A    P S  E L+ P    A + + P      G    
Sbjct: 1   MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTP----AREEQPPQHRSKRGGSVG 56

Query: 53  WCWCMCFGLAFMLAGVILGGAYLYKYFALQP---DDVYYCGIKYIKDDVILNEPSADAPA 109
               +  G+  +L G++    Y+Y+YF L     D+ + CG+ Y        E S  +  
Sbjct: 57  GVCYLSMGMVVLLMGLVFASVYIYRYFFLAQLARDNFFRCGVLY--------EDSLSSQV 108

Query: 110 ALYQTIEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPL 169
                +EE++KI+ +E  E I+VPVP+F   DPA+I+HDF + LTAY D++LDKCYVI L
Sbjct: 109 RTQMELEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIEL 168

Query: 170 NTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETY 229
           NT+IV+PPRN  ELL+N+K GTYLPQ+Y+I E MV+T+ + + + LG FIY LC+ K+TY
Sbjct: 169 NTTIVLPPRNFWELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDTY 228

Query: 230 KLQRRETIKGIQKREASNCFAIRHFENKFAVETLIC 265
           +L+RR T + I KR A NC AIRHFEN F VETLIC
Sbjct: 229 RLRRRATRRRINKRGAKNCNAIRHFENTFVVETLIC 264


>gi|60302912 integral membrane protein 2C isoform 3 [Homo sapiens]
          Length = 220

 Score =  203 bits (517), Expect = 1e-52
 Identities = 98/185 (52%), Positives = 130/185 (70%), Gaps = 8/185 (4%)

Query: 81  LQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIKIFEEEEVEFISVPVPEFADS 140
           L  D+ + CG+ Y        E S  +       +EE++KI+ +E  E I+VPVP+F   
Sbjct: 41  LARDNFFRCGVLY--------EDSLSSQVRTQMELEEDVKIYLDENYERINVPVPQFGGG 92

Query: 141 DPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIH 200
           DPA+I+HDF + LTAY D++LDKCYVI LNT+IV+PPRN  ELL+N+K GTYLPQ+Y+I 
Sbjct: 93  DPADIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFWELLMNVKRGTYLPQTYIIQ 152

Query: 201 EHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGIQKREASNCFAIRHFENKFAV 260
           E MV+T+ + + + LG FIY LC+ K+TY+L+RR T + I KR A NC AIRHFEN F V
Sbjct: 153 EEMVVTEHVSDKEALGSFIYHLCNGKDTYRLRRRATRRRINKRGAKNCNAIRHFENTFVV 212

Query: 261 ETLIC 265
           ETLIC
Sbjct: 213 ETLIC 217


>gi|4758224 integral membrane protein 2A [Homo sapiens]
          Length = 263

 Score =  201 bits (512), Expect = 4e-52
 Identities = 111/270 (41%), Positives = 163/270 (60%), Gaps = 14/270 (5%)

Query: 1   MVKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRAW----CWC 56
           MVK+ FN+  A    +K+E +   EAL+     V        ++    Q +      C  
Sbjct: 1   MVKIAFNTPTA---VQKEEARQDVEALL--SRTVRTQILTGKELRVATQEKEGSSGRCML 55

Query: 57  MCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCG-IKYIKDDVILNEPSADAPAALYQTI 115
              GL+F+LAG+I+GGA +YKYF   P    Y G + +   +   N      P  L  T 
Sbjct: 56  TLLGLSFILAGLIVGGACIYKYF--MPKSTIYRGEMCFFDSEDPANSLRGGEPNFLPVTE 113

Query: 116 EENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVM 175
           E +I+  E++ +  I VPVP F+DSDPA I+HDF K +TAYLDL L  CY++PLNTSIVM
Sbjct: 114 EADIR--EDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTSIVM 171

Query: 176 PPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRE 235
           PP+NL+EL   + +G YLPQ+Y++ E +V  + I ++ +LG FIY+LC+++++++L+RR+
Sbjct: 172 PPKNLVELFGKLASGRYLPQTYVVREDLVAVEEIRDVSNLGIFIYQLCNNRKSFRLRRRD 231

Query: 236 TIKGIQKREASNCFAIRHFENKFAVETLIC 265
            + G  KR    C+ IRHF N+F VET IC
Sbjct: 232 LLLGFNKRAIDKCWKIRHFPNEFIVETKIC 261


>gi|60302914 integral membrane protein 2C isoform 2 [Homo sapiens]
          Length = 230

 Score =  152 bits (385), Expect = 2e-37
 Identities = 94/276 (34%), Positives = 135/276 (48%), Gaps = 60/276 (21%)

Query: 1   MVKVTFNSALA--------QKEAKKDEPKSGEEALIIPPDAVAVDCKDPDDVVPVGQRRA 52
           MVK++F  A+A        +  A    P S  E L+ P    A + + P      G    
Sbjct: 1   MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTP----AREEQPPQHRSKRGGSVG 56

Query: 53  WCWCMCFGLAFMLAGVILGGAYLYKYFALQP---DDVYYCGIKYIKDDVILNEPSADAPA 109
               +  G+  +L G++    Y+Y+YF L     D+ + CG+ Y        E S  +  
Sbjct: 57  GVCYLSMGMVVLLMGLVFASVYIYRYFFLAQLARDNFFRCGVLY--------EDSLSSQV 108

Query: 110 ALYQTIEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPL 169
                +EE++KI+ +E  E I+VPVP+F   DPA+I+HDF ++                 
Sbjct: 109 RTQMELEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQRR----------------- 151

Query: 170 NTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCHDKETY 229
                               GTYLPQ+Y+I E MV+T+ + + + LG FIY LC+ K+TY
Sbjct: 152 --------------------GTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDTY 191

Query: 230 KLQRRETIKGIQKREASNCFAIRHFENKFAVETLIC 265
           +L+RR T + I KR A NC AIRHFEN F VETLIC
Sbjct: 192 RLRRRATRRRINKRGAKNCNAIRHFENTFVVETLIC 227


>gi|226246591 phosphodiesterase 2A isoform 3 [Homo sapiens]
          Length = 932

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 15/70 (21%), Positives = 34/70 (48%), Gaps = 7/70 (10%)

Query: 197 YLIHEHMVITDRIENIDHLGFFIYRLCHD------KETYKLQRRETIKGIQKREASNCFA 250
           YL+++++ +T+ +E+I+    FI  +CHD        ++++  +  +  +   E S    
Sbjct: 660 YLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGS-VME 718

Query: 251 IRHFENKFAV 260
             HF    A+
Sbjct: 719 RHHFAQAIAI 728


>gi|219802706 phosphodiesterase 2A isoform 2 [Homo sapiens]
          Length = 934

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 15/70 (21%), Positives = 34/70 (48%), Gaps = 7/70 (10%)

Query: 197 YLIHEHMVITDRIENIDHLGFFIYRLCHD------KETYKLQRRETIKGIQKREASNCFA 250
           YL+++++ +T+ +E+I+    FI  +CHD        ++++  +  +  +   E S    
Sbjct: 662 YLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGS-VME 720

Query: 251 IRHFENKFAV 260
             HF    A+
Sbjct: 721 RHHFAQAIAI 730


>gi|4505657 phosphodiesterase 2A isoform 1 [Homo sapiens]
          Length = 941

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 15/70 (21%), Positives = 34/70 (48%), Gaps = 7/70 (10%)

Query: 197 YLIHEHMVITDRIENIDHLGFFIYRLCHD------KETYKLQRRETIKGIQKREASNCFA 250
           YL+++++ +T+ +E+I+    FI  +CHD        ++++  +  +  +   E S    
Sbjct: 669 YLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGS-VME 727

Query: 251 IRHFENKFAV 260
             HF    A+
Sbjct: 728 RHHFAQAIAI 737


>gi|239735596 transmembrane protein 171 isoform 1 [Homo sapiens]
          Length = 324

 Score = 28.5 bits (62), Expect = 6.4
 Identities = 10/31 (32%), Positives = 18/31 (58%)

Query: 40  DPDDVVPVGQRRAWCWCMCFGLAFMLAGVIL 70
           DPD     G+ R +  C+ FG  F+ +G+++
Sbjct: 96  DPDRAFICGESRQFAQCLIFGFLFLTSGMLI 126


>gi|239735594 transmembrane protein 171 isoform 2 [Homo sapiens]
          Length = 323

 Score = 28.5 bits (62), Expect = 6.4
 Identities = 10/31 (32%), Positives = 18/31 (58%)

Query: 40  DPDDVVPVGQRRAWCWCMCFGLAFMLAGVIL 70
           DPD     G+ R +  C+ FG  F+ +G+++
Sbjct: 96  DPDRAFICGESRQFAQCLIFGFLFLTSGMLI 126


>gi|56549683 small CTD phosphatase 3 isoform 1 [Homo sapiens]
          Length = 276

 Score = 28.1 bits (61), Expect = 8.3
 Identities = 23/106 (21%), Positives = 46/106 (43%), Gaps = 14/106 (13%)

Query: 97  DVILNEPSADAPAALYQTIEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAY 156
           D  +  P   +P+ L   +EEN  + + ++ + I +P P      P   V D+ K     
Sbjct: 52  DYNVEAPPPSSPSVLPPLVEENGGLQKGDQRQVIPIPSPPAKYLLPEVTVLDYGK----- 106

Query: 157 LDLNLDKCYVIPLNTSIV---MPPRNLLELLINIKAGTYLPQSYLI 199
                 KC VI L+ ++V     P +  + ++ ++    + Q Y++
Sbjct: 107 ------KCVVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVL 146


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.140    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,264,234
Number of Sequences: 37866
Number of extensions: 460673
Number of successful extensions: 1063
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1049
Number of HSP's gapped (non-prelim): 12
length of query: 266
length of database: 18,247,518
effective HSP length: 100
effective length of query: 166
effective length of database: 14,460,918
effective search space: 2400512388
effective search space used: 2400512388
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.