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Search of human proteins with 11496281
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11496281 kallikrein 13 precursor [Homo sapiens]
(277 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11496281 kallikrein 13 precursor [Homo sapiens] 587 e-168
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 265 3e-71
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 265 3e-71
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 265 3e-71
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 243 2e-64
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 243 2e-64
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 241 4e-64
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 241 4e-64
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 241 4e-64
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 241 7e-64
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 241 7e-64
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 239 1e-63
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 230 1e-60
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 226 2e-59
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 223 1e-58
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 223 2e-58
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 219 2e-57
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 219 2e-57
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 218 5e-57
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 209 3e-54
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 206 1e-53
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 204 9e-53
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 200 1e-51
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 200 1e-51
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 196 1e-50
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 196 2e-50
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 196 2e-50
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 196 2e-50
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 195 3e-50
gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 192 4e-49
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 587 bits (1513), Expect = e-168
Identities = 277/277 (100%), Positives = 277/277 (100%)
Query: 1 MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLL 60
MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLL
Sbjct: 1 MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLL 60
Query: 61 CGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLN 120
CGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLN
Sbjct: 61 CGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLN 120
Query: 121 HDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCAN 180
HDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCAN
Sbjct: 121 HDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCAN 180
Query: 181 IQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCG 240
IQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCG
Sbjct: 181 IQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCG 240
Query: 241 QPDRPGVYTRVSRYVLWIRETIRKYETQQQKWLKGPQ 277
QPDRPGVYTRVSRYVLWIRETIRKYETQQQKWLKGPQ
Sbjct: 241 QPDRPGVYTRVSRYVLWIRETIRKYETQQQKWLKGPQ 277
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 265 bits (678), Expect = 3e-71
Identities = 124/257 (48%), Positives = 174/257 (67%), Gaps = 11/257 (4%)
Query: 7 VIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCGGVLV 66
++ + LAL+ G+ ++++ G+ C PHSQPWQAAL + RLLCG L+
Sbjct: 3 ILQLILLALATGLVGGETRIIK----------GFECKPHSQPWQAALFEKTRLLCGATLI 52
Query: 67 HPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIM 126
P+W+LTAAHCLK V+LG+H L + E EQ R S PHP + S + +H +DIM
Sbjct: 53 APRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIM 112
Query: 127 LLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSD 186
L+++ SPV +T ++ L LS + +T GT+C +SGWG+T+SPQ+ P TL+CANI +
Sbjct: 113 LVKMASPVSITWAVRPLTLS-SRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 171
Query: 187 EECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPG 246
++C YPG ITD M+CA +EGGKDSC+GDSGGPLVCN++L GI+SWG PC +PG
Sbjct: 172 QKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPG 231
Query: 247 VYTRVSRYVLWIRETIR 263
VYT+V +YV WI+ET++
Sbjct: 232 VYTKVCKYVDWIQETMK 248
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 265 bits (678), Expect = 3e-71
Identities = 124/257 (48%), Positives = 174/257 (67%), Gaps = 11/257 (4%)
Query: 7 VIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCGGVLV 66
++ + LAL+ G+ ++++ G+ C PHSQPWQAAL + RLLCG L+
Sbjct: 35 ILQLILLALATGLVGGETRIIK----------GFECKPHSQPWQAALFEKTRLLCGATLI 84
Query: 67 HPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIM 126
P+W+LTAAHCLK V+LG+H L + E EQ R S PHP + S + +H +DIM
Sbjct: 85 APRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIM 144
Query: 127 LLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSD 186
L+++ SPV +T ++ L LS + +T GT+C +SGWG+T+SPQ+ P TL+CANI +
Sbjct: 145 LVKMASPVSITWAVRPLTLS-SRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 203
Query: 187 EECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPG 246
++C YPG ITD M+CA +EGGKDSC+GDSGGPLVCN++L GI+SWG PC +PG
Sbjct: 204 QKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPG 263
Query: 247 VYTRVSRYVLWIRETIR 263
VYT+V +YV WI+ET++
Sbjct: 264 VYTKVCKYVDWIQETMK 280
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 265 bits (678), Expect = 3e-71
Identities = 124/257 (48%), Positives = 174/257 (67%), Gaps = 11/257 (4%)
Query: 7 VIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCGGVLV 66
++ + LAL+ G+ ++++ G+ C PHSQPWQAAL + RLLCG L+
Sbjct: 3 ILQLILLALATGLVGGETRIIK----------GFECKPHSQPWQAALFEKTRLLCGATLI 52
Query: 67 HPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIM 126
P+W+LTAAHCLK V+LG+H L + E EQ R S PHP + S + +H +DIM
Sbjct: 53 APRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIM 112
Query: 127 LLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSD 186
L+++ SPV +T ++ L LS + +T GT+C +SGWG+T+SPQ+ P TL+CANI +
Sbjct: 113 LVKMASPVSITWAVRPLTLS-SRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 171
Query: 187 EECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPG 246
++C YPG ITD M+CA +EGGKDSC+GDSGGPLVCN++L GI+SWG PC +PG
Sbjct: 172 QKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPG 231
Query: 247 VYTRVSRYVLWIRETIR 263
VYT+V +YV WI+ET++
Sbjct: 232 VYTKVCKYVDWIQETMK 248
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 243 bits (619), Expect = 2e-64
Identities = 116/225 (51%), Positives = 151/225 (67%), Gaps = 3/225 (1%)
Query: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
GG+ C PHSQPWQAAL +LLCGGVLV WVLTAAHC K V LG H+L +
Sbjct: 80 GGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGP 139
Query: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
EQ VV SIPHP Y S +H+HD+MLL+L+ L ++ + L+ ++ PG C
Sbjct: 140 EQEIPVVQSIPHPCYNSSDVE-DHNHDLMLLQLRDQASLGSKVKPISLA-DHCTQPGQKC 197
Query: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
VSGWGT TSP+ N+P TL CA +++ ++C YPG+ITD M+CAG+ +G D+C+GD
Sbjct: 198 TVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTCQGD 256
Query: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
SGGPLVC+ L GI SWG PCG+ D+PGVYT + RY+ WI++ I
Sbjct: 257 SGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 243 bits (619), Expect = 2e-64
Identities = 116/225 (51%), Positives = 151/225 (67%), Gaps = 3/225 (1%)
Query: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
GG+ C PHSQPWQAAL +LLCGGVLV WVLTAAHC K V LG H+L +
Sbjct: 35 GGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGP 94
Query: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
EQ VV SIPHP Y S +H+HD+MLL+L+ L ++ + L+ ++ PG C
Sbjct: 95 EQEIPVVQSIPHPCYNSSDVE-DHNHDLMLLQLRDQASLGSKVKPISLA-DHCTQPGQKC 152
Query: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
VSGWGT TSP+ N+P TL CA +++ ++C YPG+ITD M+CAG+ +G D+C+GD
Sbjct: 153 TVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTCQGD 211
Query: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
SGGPLVC+ L GI SWG PCG+ D+PGVYT + RY+ WI++ I
Sbjct: 212 SGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 256
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 241 bits (616), Expect = 4e-64
Identities = 117/237 (49%), Positives = 167/237 (70%), Gaps = 8/237 (3%)
Query: 29 TNGTSGFLPGGYTCFPHSQPWQAALLVQ-GRLLCGGVLVHPKWVLTAAHCLKEGLKVYLG 87
++ +S + G C H+QPWQAALL++ +L CG VLVHP+W+LTAAHC K+ +V LG
Sbjct: 60 SDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLG 119
Query: 88 KHALGRV-EAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLS 146
++L V E+G+Q+ + V SIPHP Y +H H +D+ML++L ++ T ++ + +S
Sbjct: 120 HYSLSPVYESGQQMFQGVKSIPHPGY----SHPGHSNDLMLIKLNRRIRPTKDVRPINVS 175
Query: 147 HNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGT 206
++ + GT C VSGWGTT SPQV++PK LQC NI + S + C YP +I D M CAG
Sbjct: 176 -SHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD 234
Query: 207 KEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
K G+DSC+GDSGGP+VCN +L G+VSWGD+PC +P+RPGVYT + ++ WI+ETI+
Sbjct: 235 K-AGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 241 bits (616), Expect = 4e-64
Identities = 117/237 (49%), Positives = 167/237 (70%), Gaps = 8/237 (3%)
Query: 29 TNGTSGFLPGGYTCFPHSQPWQAALLVQ-GRLLCGGVLVHPKWVLTAAHCLKEGLKVYLG 87
++ +S + G C H+QPWQAALL++ +L CG VLVHP+W+LTAAHC K+ +V LG
Sbjct: 60 SDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLG 119
Query: 88 KHALGRV-EAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLS 146
++L V E+G+Q+ + V SIPHP Y +H H +D+ML++L ++ T ++ + +S
Sbjct: 120 HYSLSPVYESGQQMFQGVKSIPHPGY----SHPGHSNDLMLIKLNRRIRPTKDVRPINVS 175
Query: 147 HNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGT 206
++ + GT C VSGWGTT SPQV++PK LQC NI + S + C YP +I D M CAG
Sbjct: 176 -SHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD 234
Query: 207 KEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
K G+DSC+GDSGGP+VCN +L G+VSWGD+PC +P+RPGVYT + ++ WI+ETI+
Sbjct: 235 K-AGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 241 bits (616), Expect = 4e-64
Identities = 117/237 (49%), Positives = 167/237 (70%), Gaps = 8/237 (3%)
Query: 29 TNGTSGFLPGGYTCFPHSQPWQAALLVQ-GRLLCGGVLVHPKWVLTAAHCLKEGLKVYLG 87
++ +S + G C H+QPWQAALL++ +L CG VLVHP+W+LTAAHC K+ +V LG
Sbjct: 60 SDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLG 119
Query: 88 KHALGRV-EAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLS 146
++L V E+G+Q+ + V SIPHP Y +H H +D+ML++L ++ T ++ + +S
Sbjct: 120 HYSLSPVYESGQQMFQGVKSIPHPGY----SHPGHSNDLMLIKLNRRIRPTKDVRPINVS 175
Query: 147 HNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGT 206
++ + GT C VSGWGTT SPQV++PK LQC NI + S + C YP +I D M CAG
Sbjct: 176 -SHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD 234
Query: 207 KEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
K G+DSC+GDSGGP+VCN +L G+VSWGD+PC +P+RPGVYT + ++ WI+ETI+
Sbjct: 235 K-AGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 241 bits (614), Expect = 7e-64
Identities = 118/225 (52%), Positives = 150/225 (66%), Gaps = 7/225 (3%)
Query: 39 GYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGE 98
G C S P+QAAL G LLCGGVL+HP WVLTAAHC K L+V+LGKH L + E+ +
Sbjct: 25 GGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQRESSQ 84
Query: 99 QVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCR 158
+ VV ++ HP+Y + +HD DIMLL L P +L+ IQ LPL + T+C
Sbjct: 85 EQSSVVRAVIHPDYDAA----SHDQDIMLLRLARPAKLSELIQPLPLERDCSANT-TSCH 139
Query: 159 VSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDS 218
+ GWG T ++P T+QCA I L S EEC YPG+IT NMLCAG ++ GKDSC+GDS
Sbjct: 140 ILGWGKTADG--DFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDS 197
Query: 219 GGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
GGPLVC L G+VSWG+ PCG ++PGVYT V RY WI++TI+
Sbjct: 198 GGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 241 bits (614), Expect = 7e-64
Identities = 118/225 (52%), Positives = 150/225 (66%), Gaps = 7/225 (3%)
Query: 39 GYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGE 98
G C S P+QAAL G LLCGGVL+HP WVLTAAHC K L+V+LGKH L + E+ +
Sbjct: 25 GGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQRESSQ 84
Query: 99 QVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCR 158
+ VV ++ HP+Y + +HD DIMLL L P +L+ IQ LPL + T+C
Sbjct: 85 EQSSVVRAVIHPDYDAA----SHDQDIMLLRLARPAKLSELIQPLPLERDCSANT-TSCH 139
Query: 159 VSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDS 218
+ GWG T ++P T+QCA I L S EEC YPG+IT NMLCAG ++ GKDSC+GDS
Sbjct: 140 ILGWGKTADG--DFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDS 197
Query: 219 GGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
GGPLVC L G+VSWG+ PCG ++PGVYT V RY WI++TI+
Sbjct: 198 GGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 239 bits (611), Expect = 1e-63
Identities = 128/270 (47%), Positives = 167/270 (61%), Gaps = 23/270 (8%)
Query: 2 WPLA-----LVIASLTLALSGGVSQES-SKVLNTNGTSGFLPGGYTCFPHSQPWQAALLV 55
WP A L+ A LA++ SQE +K++ GG+TC SQPWQAALL
Sbjct: 11 WPSAPKMFLLLTALQVLAIAMTQSQEDENKII----------GGHTCTRSSQPWQAALLA 60
Query: 56 --QGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYR 113
+ R LCGG L+ +WV+TAAHC + L+V LGKH L R EA +QV VV + HP Y
Sbjct: 61 GPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYN 120
Query: 114 RSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYP 173
HD+D+MLL+LQ P ++ ++ + ++ +PGT+CRVSGWGT +SP YP
Sbjct: 121 SR----THDNDLMLLQLQQPARIGRAVRPIEVTQACA-SPGTSCRVSGWGTISSPIARYP 175
Query: 174 KTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVS 233
+LQC NI + DE C++ YP IT M+CAG +GGKDSC+GDSGGPLVC L G+VS
Sbjct: 176 ASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVS 235
Query: 234 WGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
WG C P PGVYT + +Y WI ET+R
Sbjct: 236 WGMERCALPGYPGVYTNLCKYRSWIEETMR 265
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 230 bits (586), Expect = 1e-60
Identities = 123/271 (45%), Positives = 158/271 (58%), Gaps = 23/271 (8%)
Query: 1 MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLL 60
MW L L IA L++ +G V S+++ GG+ C HSQPWQ A+ G
Sbjct: 1 MWDLVLSIA-LSVGCTGAVPLIQSRIV----------GGWECEKHSQPWQVAVYSHGWAH 49
Query: 61 CGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLN 120
CGGVLVHP+WVLTAAHCLK+ +V+LG+H L E Q V HS PHP Y S L
Sbjct: 50 CGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSL--LK 107
Query: 121 HD---------HDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVN 171
H HD+MLL L P ++T ++ L L GTTC SGWG+ +
Sbjct: 108 HQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPAL-GTTCYASGWGSIEPEEFL 166
Query: 172 YPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGI 231
P++LQC ++ L S++ C + Y K+T+ MLCAG GGKD+C GDSGGPLVCN L GI
Sbjct: 167 RPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGI 226
Query: 232 VSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
SWG PC P++P VYT+V Y WI++TI
Sbjct: 227 TSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 226 bits (575), Expect = 2e-59
Identities = 110/232 (47%), Positives = 142/232 (61%), Gaps = 8/232 (3%)
Query: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
GG+ C HSQPWQ + +GR +CGGVLVHP+WVLTAAHC++ + LG+H+L E
Sbjct: 27 GGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDT 86
Query: 98 EQVREVVHSIPHPEYRRSPTHL-------NHDHDIMLLELQSPVQLTGYIQTLPLSHNNR 150
QV +V HS PHP Y S + HD+MLL L P +LT ++ + L
Sbjct: 87 GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEP 146
Query: 151 LTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGG 210
GTTC SGWG+ + PK LQC ++ + S++ C QV+P K+T MLCAG GG
Sbjct: 147 AL-GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGG 205
Query: 211 KDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
K +C GDSGGPLVCN L GI SWG PC P+RP +YT+V Y WI++TI
Sbjct: 206 KSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 223 bits (569), Expect = 1e-58
Identities = 120/274 (43%), Positives = 157/274 (57%), Gaps = 29/274 (10%)
Query: 1 MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLL 60
MW ++ +L+ L+ +Q+ K+L G C PHSQPWQ AL +GR
Sbjct: 1 MW----LLLTLSFLLASTAAQDGDKLLE----------GDECAPHSQPWQVALYERGRFN 46
Query: 61 CGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLN 120
CG L+ P WVL+AAHC ++V LG+H L + + EQ+R IPHP Y +
Sbjct: 47 CGASLISPHWVLSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEAR----S 102
Query: 121 HDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWG--------TTTSP--QV 170
H +DIMLL L P +L ++ L PG C VSGWG T SP QV
Sbjct: 103 HRNDIMLLRLVQPARLNPQVRPAVLP-TRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQV 161
Query: 171 NYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYG 230
+ P TL CANI + SD C + YPG++T+ M+CAG + G +SCEGDSGGPLVC L G
Sbjct: 162 SLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQG 221
Query: 231 IVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIRK 264
IVSWGD PC +PGVYT+V Y+ WIRET+++
Sbjct: 222 IVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKR 255
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 223 bits (567), Expect = 2e-58
Identities = 109/223 (48%), Positives = 142/223 (63%), Gaps = 1/223 (0%)
Query: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
G C P+SQPWQA L RL CG L+ +W+LTAAHC K L V LG+H L + E
Sbjct: 25 GAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWKWEGP 84
Query: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
EQ+ V PHP + + + +H+ DIML+ L +L+ +Q L LS ++PG C
Sbjct: 85 EQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTC-VSPGMQC 143
Query: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
+SGWG +SP+ +P TLQCANI + ++ C YPG I+D+MLCAG EGG+ SC+GD
Sbjct: 144 LISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEGGRGSCQGD 203
Query: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRE 260
SGGPLVCN TL G+VS G PC +P RP VYT V Y+ WI+E
Sbjct: 204 SGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQE 246
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 219 bits (558), Expect = 2e-57
Identities = 116/263 (44%), Positives = 161/263 (61%), Gaps = 18/263 (6%)
Query: 3 PLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCG 62
PL +++ SL L +G +Q K+++ G C S PWQ ALL +L CG
Sbjct: 8 PLQILLLSLALETAGEEAQ-GDKIID----------GAPCARGSHPWQVALLSGNQLHCG 56
Query: 63 GVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHD 122
GVLV+ +WVLTAAHC V+LG LG A Q + S HP Y + TH+N
Sbjct: 57 GVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYS-TQTHVN-- 111
Query: 123 HDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQ 182
D+ML++L S +L+ ++ + L PGTTC VSGWGTTTSP V +P L C +++
Sbjct: 112 -DLMLVKLNSQARLSSMVKKVRLPSRCE-PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVK 169
Query: 183 LRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQP 242
L S ++C +VY + ++MLCAG + K++C GDSGGPLVC TL G+VSWG FPCGQP
Sbjct: 170 LISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQP 229
Query: 243 DRPGVYTRVSRYVLWIRETIRKY 265
+ PGVYT+V ++ WI +T++K+
Sbjct: 230 NDPGVYTQVCKFTKWINDTMKKH 252
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 219 bits (558), Expect = 2e-57
Identities = 116/263 (44%), Positives = 161/263 (61%), Gaps = 18/263 (6%)
Query: 3 PLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCG 62
PL +++ SL L +G +Q K+++ G C S PWQ ALL +L CG
Sbjct: 8 PLQILLLSLALETAGEEAQ-GDKIID----------GAPCARGSHPWQVALLSGNQLHCG 56
Query: 63 GVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHD 122
GVLV+ +WVLTAAHC V+LG LG A Q + S HP Y + TH+N
Sbjct: 57 GVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYS-TQTHVN-- 111
Query: 123 HDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQ 182
D+ML++L S +L+ ++ + L PGTTC VSGWGTTTSP V +P L C +++
Sbjct: 112 -DLMLVKLNSQARLSSMVKKVRLPSRCE-PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVK 169
Query: 183 LRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQP 242
L S ++C +VY + ++MLCAG + K++C GDSGGPLVC TL G+VSWG FPCGQP
Sbjct: 170 LISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQP 229
Query: 243 DRPGVYTRVSRYVLWIRETIRKY 265
+ PGVYT+V ++ WI +T++K+
Sbjct: 230 NDPGVYTQVCKFTKWINDTMKKH 252
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 218 bits (555), Expect = 5e-57
Identities = 111/226 (49%), Positives = 143/226 (63%), Gaps = 5/226 (2%)
Query: 39 GYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGE 98
G C +SQPWQ L L CGGVL+ +WVLTAAHC V LG+H+L +++ E
Sbjct: 25 GTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTE 84
Query: 99 QVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCR 158
Q+R S+ HP Y + T +H+HD+ LL L+ PV++T +Q LPL N+ T GT C
Sbjct: 85 QIRHSGFSVTHPGYLGAST--SHEHDLRLLRLRLPVRVTSSVQPLPLP-NDCATAGTECH 141
Query: 159 VSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDS 218
VSGWG T P+ +P LQC N+ + S C VYPG+IT NM+CAG G+D+C+GDS
Sbjct: 142 VSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVP-GQDACQGDS 200
Query: 219 GGPLVCNRTLYGIVSWGDF-PCGQPDRPGVYTRVSRYVLWIRETIR 263
GGPLVC L G+VSWG PCGQ PGVYT + +YV WIR +R
Sbjct: 201 GGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMR 246
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 209 bits (531), Expect = 3e-54
Identities = 109/270 (40%), Positives = 153/270 (56%), Gaps = 20/270 (7%)
Query: 1 MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLL 60
MW L L +A L+L +G S+++ GG+ C HSQPWQAAL
Sbjct: 1 MWFLVLCLA-LSLGGTGAAPPIQSRIV----------GGWECEQHSQPWQAALYHFSTFQ 49
Query: 61 CGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRS----- 115
CGG+LVH +WVLTAAHC+ + +++LG+H L E Q V S PHP + S
Sbjct: 50 CGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENH 109
Query: 116 --PTHLNHDHDIMLLELQSPVQ-LTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNY 172
++ HD+MLL L P +T ++ + L G+TC SGWG+ ++
Sbjct: 110 TRQADEDYSHDLMLLRLTEPADTITDAVKVVELP-TEEPEVGSTCLASGWGSIEPENFSF 168
Query: 173 PKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIV 232
P LQC ++++ ++EC++ + K+TD MLC G EGGKD+C GDSGGPL+C+ L G+
Sbjct: 169 PDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVT 228
Query: 233 SWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
SWG PCG P++P V RV YV WI +TI
Sbjct: 229 SWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 258
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 206 bits (525), Expect = 1e-53
Identities = 106/219 (48%), Positives = 136/219 (62%), Gaps = 5/219 (2%)
Query: 39 GYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGE 98
G C +SQPWQ L L CGGVL+ +WVLTAAHC V LG+H+L +++ E
Sbjct: 25 GTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTE 84
Query: 99 QVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCR 158
Q+R S+ HP Y + T +H+HD+ LL L+ PV++T +Q LPL N+ T GT C
Sbjct: 85 QIRHSGFSVTHPGYLGAST--SHEHDLRLLRLRLPVRVTSSVQPLPLP-NDCATAGTECH 141
Query: 159 VSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDS 218
VSGWG T P+ +P LQC N+ + S C VYPG+IT NM+CAG G+D+C+GDS
Sbjct: 142 VSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVP-GQDACQGDS 200
Query: 219 GGPLVCNRTLYGIVSWGDF-PCGQPDRPGVYTRVSRYVL 256
GGPLVC L G+VSWG PCGQ PGVYT + L
Sbjct: 201 GGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICNSTL 239
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 204 bits (518), Expect = 9e-53
Identities = 103/225 (45%), Positives = 136/225 (60%), Gaps = 7/225 (3%)
Query: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
GGY C +S P+Q +L G CGG L++ +WV++A HC K ++V LG+H + +E
Sbjct: 26 GGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGN 84
Query: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
EQ I HP+Y R + +DIML++L S + + T+ L T GT C
Sbjct: 85 EQFINAAKIIRHPQYDRKTLN----NDIMLIKLSSRAVINARVSTISLPTAPPAT-GTKC 139
Query: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
+SGWG T S +YP LQC + + S +C YPGKIT NM C G EGGKDSC+GD
Sbjct: 140 LISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGD 199
Query: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
SGGP+VCN L G+VSWGD C Q ++PGVYT+V YV WI+ TI
Sbjct: 200 SGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTI 243
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 200 bits (508), Expect = 1e-51
Identities = 102/225 (45%), Positives = 137/225 (60%), Gaps = 7/225 (3%)
Query: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
GGYTC +S P+Q +L G CGG L+ +WV++AAHC K ++V LG+H + +E
Sbjct: 83 GGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGN 141
Query: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
EQ I HP+Y R D+DIML++L SP + + T+ L GT C
Sbjct: 142 EQFINAAKIIRHPKYNRDTL----DNDIMLIKLSSPAVINARVSTISLP-TAPPAAGTEC 196
Query: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
+SGWG T S +YP L+C + + + EC+ YPGKIT++M C G EGGKDSC+ D
Sbjct: 197 LISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRD 256
Query: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
SGGP+VCN L G+VSWG C +RPGVYT+V YV WI++TI
Sbjct: 257 SGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 300
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 200 bits (508), Expect = 1e-51
Identities = 102/225 (45%), Positives = 137/225 (60%), Gaps = 7/225 (3%)
Query: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
GGYTC +S P+Q +L G CGG L+ +WV++AAHC K ++V LG+H + +E
Sbjct: 26 GGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGN 84
Query: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
EQ I HP+Y R D+DIML++L SP + + T+ L GT C
Sbjct: 85 EQFINAAKIIRHPKYNRDTL----DNDIMLIKLSSPAVINARVSTISLP-TAPPAAGTEC 139
Query: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
+SGWG T S +YP L+C + + + EC+ YPGKIT++M C G EGGKDSC+ D
Sbjct: 140 LISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRD 199
Query: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
SGGP+VCN L G+VSWG C +RPGVYT+V YV WI++TI
Sbjct: 200 SGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 243
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 196 bits (499), Expect = 1e-50
Identities = 108/263 (41%), Positives = 153/263 (58%), Gaps = 19/263 (7%)
Query: 3 PLALVIASLTLALSGG-VSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLC 61
P + L L ++G VS S+++N G C PHSQPWQAAL+++ L C
Sbjct: 7 PWGWFLGYLILGVAGSLVSGSCSQIIN----------GEDCSPHSQPWQAALVMENELFC 56
Query: 62 GGVLVHPKWVLTAAHCLKEGLKVYLGKHAL-GRVEAGEQVREVVHSIPHPEYRRSPTHLN 120
GVLVHP+WVL+AAHC + + LG H+L E G Q+ E S+ HPEY R P N
Sbjct: 57 SGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNR-PLLAN 115
Query: 121 HDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCAN 180
D+ML++L V + I+++ ++ + T G +C VSGWG + ++ P LQC N
Sbjct: 116 ---DLMLIKLDESVSESDTIRSISIA-SQCPTAGNSCLVSGWGLLANGRM--PTVLQCVN 169
Query: 181 IQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCG 240
+ + S+E C ++Y +M CAG KDSC GDSGGPL+CN L G+VS+G PCG
Sbjct: 170 VSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCG 229
Query: 241 QPDRPGVYTRVSRYVLWIRETIR 263
Q PGVYT + ++ WI +T++
Sbjct: 230 QVGVPGVYTNLCKFTEWIEKTVQ 252
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 196 bits (497), Expect = 2e-50
Identities = 100/229 (43%), Positives = 138/229 (60%), Gaps = 7/229 (3%)
Query: 39 GYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGE 98
G C SQPWQ +L C GVLV WVLTAAHC + L +G L ++ GE
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ-GE 107
Query: 99 QVREVVHSIPHPEYRRSPTHL----NHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPG 154
Q+R S+ HP+Y + + +HD+MLL+L PV L ++ L L + PG
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCA-QPG 166
Query: 155 TTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSC 214
C+V+GWGTT + +V Y K L C++I + S +EC YPG +T+NM+CAG + G+D C
Sbjct: 167 DQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGL-DRGQDPC 225
Query: 215 EGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
+ DSGGPLVC+ TL GI+SWG +PCG P VYT++ +Y+ WI + IR
Sbjct: 226 QSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 274
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 196 bits (497), Expect = 2e-50
Identities = 100/229 (43%), Positives = 138/229 (60%), Gaps = 7/229 (3%)
Query: 39 GYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGE 98
G C SQPWQ +L C GVLV WVLTAAHC + L +G L ++ GE
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ-GE 107
Query: 99 QVREVVHSIPHPEYRRSPTHL----NHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPG 154
Q+R S+ HP+Y + + +HD+MLL+L PV L ++ L L + PG
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCA-QPG 166
Query: 155 TTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSC 214
C+V+GWGTT + +V Y K L C++I + S +EC YPG +T+NM+CAG + G+D C
Sbjct: 167 DQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGL-DRGQDPC 225
Query: 215 EGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
+ DSGGPLVC+ TL GI+SWG +PCG P VYT++ +Y+ WI + IR
Sbjct: 226 QSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 274
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 196 bits (497), Expect = 2e-50
Identities = 100/229 (43%), Positives = 138/229 (60%), Gaps = 7/229 (3%)
Query: 39 GYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGE 98
G C SQPWQ +L C GVLV WVLTAAHC + L +G L ++ GE
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ-GE 107
Query: 99 QVREVVHSIPHPEYRRSPTHL----NHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPG 154
Q+R S+ HP+Y + + +HD+MLL+L PV L ++ L L + PG
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCA-QPG 166
Query: 155 TTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSC 214
C+V+GWGTT + +V Y K L C++I + S +EC YPG +T+NM+CAG + G+D C
Sbjct: 167 DQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGL-DRGQDPC 225
Query: 215 EGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
+ DSGGPLVC+ TL GI+SWG +PCG P VYT++ +Y+ WI + IR
Sbjct: 226 QSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 274
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 195 bits (496), Expect = 3e-50
Identities = 101/225 (44%), Positives = 133/225 (59%), Gaps = 7/225 (3%)
Query: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
GGY C +S P+Q +L G CGG L+ +WV++A HC K ++V LG+H + +E
Sbjct: 26 GGYICEENSVPYQVSLN-SGYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEHNIEVLEGN 84
Query: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
EQ I HP+Y D+DI+L++L SP + + + L GT
Sbjct: 85 EQFINAAKIIRHPKYNSRTL----DNDILLIKLSSPAVINSRVSAISLP-TAPPAAGTES 139
Query: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
+SGWG T S +YP LQC + + S EC YPGKIT+NM C G EGGKDSC+GD
Sbjct: 140 LISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSCQGD 199
Query: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
SGGP+V N L GIVSWG + C Q +RPGVYT+V YV WI++TI
Sbjct: 200 SGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIKDTI 243
>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
sapiens]
Length = 218
Score = 192 bits (487), Expect = 4e-49
Identities = 96/225 (42%), Positives = 126/225 (56%), Gaps = 37/225 (16%)
Query: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
GG+ C HSQPWQ + +GR +CGGVLVHP+WVLTAAHC+++ G
Sbjct: 27 GGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRK---------------PG 71
Query: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
+ + HD+MLL L P +LT ++ + L GTTC
Sbjct: 72 D---------------------DSSHDLMLLRLSEPAELTDAVKVMDLPTQEPAL-GTTC 109
Query: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
SGWG+ + PK LQC ++ + S++ C QV+P K+T MLCAG GGK +C GD
Sbjct: 110 YASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGD 169
Query: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
SGGPLVCN L GI SWG PC P+RP +YT+V Y WI++TI
Sbjct: 170 SGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 214
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,526,035
Number of Sequences: 37866
Number of extensions: 619774
Number of successful extensions: 1940
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1244
Number of HSP's gapped (non-prelim): 208
length of query: 277
length of database: 18,247,518
effective HSP length: 101
effective length of query: 176
effective length of database: 14,423,052
effective search space: 2538457152
effective search space used: 2538457152
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.