Search of human proteins with 114205383

Search of human proteins with 114205383

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|114205383 secretin receptor precursor [Homo sapiens]
         (440 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|114205383 secretin receptor precursor [Homo sapiens]               904   0.0  
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]   421   e-118
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar...   413   e-115
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]   385   e-107
gi|58530851 growth hormone releasing hormone receptor isoform a ...   338   6e-93
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]    319   4e-87
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]          300   2e-81
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi...   298   9e-81
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]    292   4e-79
gi|4503947 glucagon receptor [Homo sapiens]                           285   6e-77
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]     283   2e-76
gi|58530853 growth hormone releasing hormone receptor isoform b ...   254   8e-68
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap...   208   9e-54
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2...   200   2e-51
gi|5031621 calcitonin receptor-like [Homo sapiens]                    189   6e-48
gi|4502547 calcitonin receptor [Homo sapiens]                         187   2e-47
gi|223717971 corticotropin releasing hormone receptor 1 isoform ...   185   8e-47
gi|223717978 corticotropin releasing hormone receptor 1 isoform ...   184   1e-46
gi|223717985 corticotropin releasing hormone receptor 1 isoform ...   171   1e-42
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]              92   9e-19
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]           90   5e-18
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]           90   5e-18
gi|40807489 egf-like module containing, mucin-like, hormone rece...    87   2e-17
gi|6912464 latrophilin 2 precursor [Homo sapiens]                      84   3e-16
gi|133930786 egf-like module-containing mucin-like receptor 3 [H...    83   4e-16
gi|23397681 egf-like module containing, mucin-like, hormone rece...    81   2e-15
gi|23397693 egf-like module containing, mucin-like, hormone rece...    81   2e-15
gi|23397691 egf-like module containing, mucin-like, hormone rece...    81   2e-15
gi|23397689 egf-like module containing, mucin-like, hormone rece...    81   2e-15
gi|23397687 egf-like module containing, mucin-like, hormone rece...    81   2e-15

>gi|114205383 secretin receptor precursor [Homo sapiens]
          Length = 440

 Score =  904 bits (2336), Expect = 0.0
 Identities = 440/440 (100%), Positives = 440/440 (100%)

Query: 1   MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE 60
           MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE
Sbjct: 1   MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTE 60

Query: 61  QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPN 120
           QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPN
Sbjct: 61  QPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPN 120

Query: 121 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH 180
           LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH
Sbjct: 121 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH 180

Query: 181 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL 240
           LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL
Sbjct: 181 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL 240

Query: 241 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRG 300
           HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRG
Sbjct: 241 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRG 300

Query: 301 PVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAF 360
           PVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAF
Sbjct: 301 PVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAF 360

Query: 361 SPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFS 420
           SPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFS
Sbjct: 361 SPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFS 420

Query: 421 NSTKASHLEQSQGTCRTSII 440
           NSTKASHLEQSQGTCRTSII
Sbjct: 421 NSTKASHLEQSQGTCRTSII 440


>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
          Length = 457

 Score =  421 bits (1083), Expect = e-118
 Identities = 213/418 (50%), Positives = 284/418 (67%), Gaps = 18/418 (4%)

Query: 1   MRPHLSPPLQQL-LLPVLLACAAHSTGA----LPRLCDVLQVLWEEQDQCLQELSREQTG 55
           MRP    P + L +L   LA A    G     L   CD +Q++  +  QCL+E       
Sbjct: 1   MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQ----- 55

Query: 56  DLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNG-SLFRNCTQDGWSE 114
               E    GC  MWDN++CWP++  G++V + CP   ++ +S  G ++ R+CT +GW+ 
Sbjct: 56  ---LENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTH 112

Query: 115 TFPRPN-LACGVNVNDSS-NEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHC 172
             P P  +ACG++   +S +E++  +   +K  YT+GY  SL  LLVA  IL  FR+LHC
Sbjct: 113 LEPGPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHC 172

Query: 173 TRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSW 232
           TRNYIHMHLF+SFILRA + FIKD  LF S +   C     GCK  MV FQYC+MAN+ W
Sbjct: 173 TRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFW 232

Query: 233 LLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANA 292
           LLVEGLYL+TLLA+SFFSERKY  G++  GWG P+ F  +W IAR   ED GCWD   N+
Sbjct: 233 LLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWD-TINS 291

Query: 293 SIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFG 352
           S+WWII+GP++ SIL+NFILFI I+RIL++KLR  + R ++ S Y RLARSTLLLIPLFG
Sbjct: 292 SLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFG 351

Query: 353 IHYIVFAFSPED-AMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLR 409
           +HYI+FAF P++   E+++ FEL +GSFQG VVA+LYCFLNGEVQ E+++KW++WHL+
Sbjct: 352 VHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQ 409


>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
           receptor type I precursor [Homo sapiens]
          Length = 468

 Score =  413 bits (1062), Expect = e-115
 Identities = 206/432 (47%), Positives = 273/432 (63%), Gaps = 34/432 (7%)

Query: 40  EEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLT-- 97
           +EQ  CL+++ R     +G     PGC GMWDNI+CW  +  G MV V CP   R+    
Sbjct: 29  KEQAMCLEKIQRANEL-MGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPD 87

Query: 98  ---------------------SRNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRH 136
                                S  G + RNCT+DGWSE FP    ACG +  +S    + 
Sbjct: 88  QVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQD 147

Query: 137 SYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKD 196
            Y L +K +YTVGYS+SLV L  A+ ILC FR+LHCTRN+IHM+LFVSF+LRA+S FIKD
Sbjct: 148 YYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKD 207

Query: 197 AVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQ 256
            +L++  D  +C      CK VMV F YC+++NY WL +EGLYL TLL  +FF ER+Y  
Sbjct: 208 WILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFY 267

Query: 257 GFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINI 316
            +   GWG+P + V +WA  R + +D GCWD+N + ++WW+I+GPV+ SI++NF+LFI I
Sbjct: 268 WYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGI 327

Query: 317 LRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQ-LFFELA 375
           + IL++KL++ +  GNE S Y RLARSTLLLIPLFGIHY VFAFSPE+  + + L FEL 
Sbjct: 328 IVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELG 387

Query: 376 LGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREF---------PLHPVASFSNSTKAS 426
           LGSFQG VVAVLYCFLNGEVQ E+++KW+ W +  +         P    +  +  T+ S
Sbjct: 388 LGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLS 447

Query: 427 HLEQSQGTCRTS 438
            L +S    R S
Sbjct: 448 ILSKSSSQIRMS 459


>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
          Length = 438

 Score =  385 bits (989), Expect = e-107
 Identities = 195/401 (48%), Positives = 266/401 (66%), Gaps = 15/401 (3%)

Query: 9   LQQLLLPVLLAC-AAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCE 67
           ++ LL P LL C       ++   C     + EE+ +C  EL R QT      +    C 
Sbjct: 1   MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCA-ELLRSQT------EKHKACS 53

Query: 68  GMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGVNV 127
           G+WDNI+CW  +  G  V V CP+      S+ G++ +NCT DGWSETFP    ACG + 
Sbjct: 54  GVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYS- 112

Query: 128 NDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFIL 187
            D  +E + ++ + +K +YT+GYS SL+ L     ILC FR+LHCTRNYIH++LF+SFIL
Sbjct: 113 -DPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFIL 171

Query: 188 RALSNFIKDAVLFSSDDVTYCDAHRA---GCKLVMVLFQYCIMANYSWLLVEGLYLHTLL 244
           RA+S  +KD VL+SS    +C    +   GCKL +V  QYCIMAN+ WLLVEGLYLHTLL
Sbjct: 172 RAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLL 231

Query: 245 AISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRGPVIL 304
            ++    R+    ++  GWG P + +  W  AR +LED GCWD N ++  WW+IR P+++
Sbjct: 232 -VAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILI 290

Query: 305 SILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSP-E 363
           SI++NF+LFI+I+RIL++KL + +  GN+ S YKRLA+STLLLIPLFG+HY+VFA  P  
Sbjct: 291 SIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPIS 350

Query: 364 DAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQ 404
            + + Q+ FEL LGSFQGLVVAVLYCFLN EVQ E+++KW+
Sbjct: 351 ISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWR 391


>gi|58530851 growth hormone releasing hormone receptor isoform a
           precursor [Homo sapiens]
          Length = 423

 Score =  338 bits (867), Expect = 6e-93
 Identities = 168/373 (45%), Positives = 232/373 (62%), Gaps = 10/373 (2%)

Query: 32  CDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPR 91
           CD +  L E++  CLQ         LG       C   WD + CWP++  G  V + CP 
Sbjct: 28  CDFITQLREDESACLQAAEEMPNTTLG-------CPATWDGLLCWPTAGSGEWVTLPCPD 80

Query: 92  FLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYS 151
           F    +S +G++ R+CT  GWSE FP   +AC V +   + E+  SY   +K++YTVG+S
Sbjct: 81  FFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEE--SYFSTVKIIYTVGHS 138

Query: 152 SSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAH 211
            S+V L VA+ IL A RRLHC RNY+H  LF +FIL+A + F+KDA LF SDD  +C   
Sbjct: 139 ISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFS 198

Query: 212 RAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVA 271
              CK+ +    +  M N+SWLL E +YL+ LLA +  S R+     V  GWG P +F  
Sbjct: 199 TVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTG 258

Query: 272 LWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRG 331
            W   +   ED+ CWD++  +  WWII+GP++LS+ +NF LF+NI+RIL+RKL   +   
Sbjct: 259 TWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSL 318

Query: 332 NEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDA-MEIQLFFELALGSFQGLVVAVLYCF 390
           +  S Y RL++STL LIPLFGIHYI+F F P++A + I+L  EL LGSFQG +VA+LYCF
Sbjct: 319 HTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCF 378

Query: 391 LNGEVQLEVQKKW 403
           LN EV+ E+ +KW
Sbjct: 379 LNQEVRTEISRKW 391


>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
          Length = 593

 Score =  319 bits (817), Expect = 4e-87
 Identities = 168/374 (44%), Positives = 232/374 (62%), Gaps = 33/374 (8%)

Query: 66  CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGV 125
           C   WD+I CWP   PG +V V CP ++     + G  +R C ++G  E  P  N     
Sbjct: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHK-GHAYRRCDRNGSWELVPGHNRTWAN 166

Query: 126 N---VNDSSNEKRHSYLL-KLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHL 181
               V   +NE R   +  +L ++YTVGYS SL  L VA+ IL  FRRLHCTRNYIHMHL
Sbjct: 167 YSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHL 226

Query: 182 FVSFILRALSNFIKDAVLFSSDDVTYCD---------------------AHRAGCKLVMV 220
           F+SF+LRA+S F+KDAVL+S   +   +                     A  AGC++ + 
Sbjct: 227 FLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVT 286

Query: 221 LFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFL 280
            F Y +  NY W+LVEGLYLH+L+ ++FFSE+KYL GF  FGWG PA+FVA+W   R  L
Sbjct: 287 FFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATL 346

Query: 281 EDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLR-TQETRGNEVSHYKR 339
            + GCWD+ ++ +  WII+ P++ SI++NFILFINI+R+L  KLR T   R +    Y++
Sbjct: 347 ANTGCWDL-SSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRK 405

Query: 340 LARSTLLLIPLFGIHYIVFAFSPEDAM-----EIQLFFELALGSFQGLVVAVLYCFLNGE 394
           L +STL+L+PLFG+HYIVF  +P   +     ++Q+ +E+   SFQG  VA++YCF NGE
Sbjct: 406 LLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGE 465

Query: 395 VQLEVQKKWQQWHL 408
           VQ E++K W +W L
Sbjct: 466 VQAEIKKSWSRWTL 479


>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
          Length = 463

 Score =  300 bits (768), Expect = 2e-81
 Identities = 181/466 (38%), Positives = 255/466 (54%), Gaps = 50/466 (10%)

Query: 9   LQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPG--- 65
           L  LLL ++        GA   L + +Q   E + QC + L         TE P P    
Sbjct: 10  LALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSL---------TEDPPPATDL 60

Query: 66  -CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTS-RNGSLFRNCTQDG-W----SETFPR 118
            C   +D  +CWP   PG  V V CP +L   +S   G ++R CT +G W    + + P 
Sbjct: 61  FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW 120

Query: 119 PNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIH 178
            +L+                LL L ++YTVGY+ S   L++A  IL  FR LHCTRNYIH
Sbjct: 121 RDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIH 180

Query: 179 MHLFVSFILRALSNFIKDAVL---FSSDD--------VTYCDAHRAGCKLVMVLFQYCIM 227
           ++LF SFILRALS FIKDA L   +S+          ++Y D+    C+LV +L QYC+ 
Sbjct: 181 LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDS--LSCRLVFLLMQYCVA 238

Query: 228 ANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWD 287
           ANY WLLVEG+YL+TLLA S  SE+   + +V+ GWG P +FV  W I ++  ED GCW 
Sbjct: 239 ANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWT 298

Query: 288 INANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLL 347
            N+N + W IIR P++ +I +NF++F+ ++ I++ KL+       ++    RLA+STL L
Sbjct: 299 RNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIK--CRLAKSTLTL 356

Query: 348 IPLFGIHYIVFAFSPEDAME-----IQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKK 402
           IPL G H ++FAF  ++        I+LF EL+  SFQGL+VA+LYCF+N EVQLE +K 
Sbjct: 357 IPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKS 416

Query: 403 WQQWHLREFPLH----------PVASFSNSTKASHLEQSQGTCRTS 438
           W++W L    +           P +S S+   A        TC+ S
Sbjct: 417 WERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGS-SMYTATCQAS 461


>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
           sapiens]
          Length = 553

 Score =  298 bits (762), Expect = 9e-81
 Identities = 168/422 (39%), Positives = 240/422 (56%), Gaps = 34/422 (8%)

Query: 8   PLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCE 67
           P +  L  VLL      TG+L  L +  +   + +  CL++L +E +G          C 
Sbjct: 48  PGRPFLTLVLLVSIKQVTGSL--LEETTRKWAQYKQACLRDLLKEPSGIF--------CN 97

Query: 68  GMWDNISCWPSSVPGRMVEVECPRFLRMLTSRN-GSLFRNCTQDGWSETFP------RPN 120
           G +D   CWP S PG  V V CP +L   +  + G  +R+C   G  +T        + +
Sbjct: 98  GTFDQYVCWPHSSPGN-VSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDD 156

Query: 121 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH 180
             C  N +   N  R++ L  L++MYTVGYS SL+ L +AL +L   R+LHCTRNYIHM+
Sbjct: 157 SECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMN 216

Query: 181 LFVSFILRALSNFIKDAVLFSSDD---------VTYCDAHRAGCKLVMVLFQYCIMANYS 231
           LF SFILR L+  +KD V ++S           ++Y       C+ V VL  Y + ANY 
Sbjct: 217 LFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYL 276

Query: 232 WLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINAN 291
           WLLVEGLYLHTLL  +   ER+    ++  GW  P +FV  W  AR  LE+ GCW  N N
Sbjct: 277 WLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGN 336

Query: 292 ASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLF 351
             IWWIIRGP++L + +NF +F+ IL++L+ KL+  +    +  +  RLA+STL+LIPL 
Sbjct: 337 KKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKY--RLAKSTLVLIPLL 394

Query: 352 GIHYIVFAFSPEDAME-----IQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQW 406
           G+H I+F+F  +D +E     I+LF +L L SF G +VA+ Y F NGEV+ E++K W ++
Sbjct: 395 GVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRF 454

Query: 407 HL 408
            L
Sbjct: 455 LL 456


>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
          Length = 550

 Score =  292 bits (748), Expect = 4e-79
 Identities = 158/383 (41%), Positives = 223/383 (58%), Gaps = 52/383 (13%)

Query: 66  CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDG-----------WSE 114
           C   WD + CWP    G++  V CP ++     + G  FR+C  +G           W+ 
Sbjct: 63  CFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHK-GVAFRHCNPNGTWDFMHSLNKTWAN 121

Query: 115 -----TFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRR 169
                 F +P+++ G          +  +  +L VMYTVGYS S   L VA+ I+  FRR
Sbjct: 122 YSDCLRFLQPDISIG----------KQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRR 171

Query: 170 LHCTRNYIHMHLFVSFILRALSNFIKDAVLFS------------------SDDVTYCDAH 211
           LHCTRNYIHMHLFVSF+LRA S F+KD V+ +                  S + T  D  
Sbjct: 172 LHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKS 231

Query: 212 R-AGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFV 270
           +  GCK+ +V+F Y +  NY W+LVEGLYLH L+ ++FFS+ KYL GF+  GWG PA FV
Sbjct: 232 QYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFV 291

Query: 271 ALWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETR 330
           A WA+AR  L D  CW+++A   I WI + P++ +I +NFILF+N +R+L  K+      
Sbjct: 292 AAWAVARATLADARCWELSA-GDIKWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAV 350

Query: 331 GNEV-SHYKRLARSTLLLIPLFGIHYIVFAFSPED----AMEIQLFFELALGSFQGLVVA 385
           G++    Y++LA+STL+L+ +FG+HYIVF   P        EI++  EL   SFQG  V+
Sbjct: 351 GHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVS 410

Query: 386 VLYCFLNGEVQLEVQKKWQQWHL 408
           ++YC+ NGEVQ EV+K W +W+L
Sbjct: 411 IIYCYCNGEVQAEVKKMWSRWNL 433


>gi|4503947 glucagon receptor [Homo sapiens]
          Length = 477

 Score =  285 bits (729), Expect = 6e-77
 Identities = 173/433 (39%), Positives = 240/433 (55%), Gaps = 41/433 (9%)

Query: 3   PHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQ-DQCLQELSREQTGDLGTEQ 61
           P   P    LLL +LLAC      A  ++ D L   W+   DQC   LS           
Sbjct: 2   PPCQPQRPLLLLLLLLACQPQVPSA--QVMDFLFEKWKLYGDQCHHNLSL---------L 50

Query: 62  PVPG---CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTS-RNGSLFRNCTQDGWSETFP 117
           P P    C   +D  SCWP +       + CP +L      ++  +F+ C  DG     P
Sbjct: 51  PPPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGP 110

Query: 118 RPN-----LACGVNVNDSSNEKRHSYLLK-LKVMYTVGYSSSLVMLLVALGILCAFRRLH 171
           R         C ++  +   +K  + +    +VMYTVGYS SL  LL+AL IL    +LH
Sbjct: 111 RGQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLH 170

Query: 172 CTRNYIHMHLFVSFILRALSNFIKDAVLFS------SDDVTYC----DAHRAGCKLVMVL 221
           CTRN IH +LF SF+L+A S  + D +L +       DD++      D   AGC++  V 
Sbjct: 171 CTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVF 230

Query: 222 FQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLE 281
            QY I+ANY WLLVEGLYLH LL ++   ER +   ++  GWG+P +FV  WA+ +   E
Sbjct: 231 MQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFE 290

Query: 282 DVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYK-RL 340
           +V CW  N N   WWI+R PV L+ILINF +F+ I+++L+ KLR ++    +   YK RL
Sbjct: 291 NVQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTD---YKFRL 347

Query: 341 ARSTLLLIPLFGIHYIVFAFSPEDAME-----IQLFFELALGSFQGLVVAVLYCFLNGEV 395
           A+STL LIPL G+H +VFAF  ++  +      +LFF+L L SFQGL+VAVLYCFLN EV
Sbjct: 348 AKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEV 407

Query: 396 QLEVQKKWQQWHL 408
           Q E++++W +W L
Sbjct: 408 QSELRRRWHRWRL 420


>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
          Length = 466

 Score =  283 bits (724), Expect = 2e-76
 Identities = 168/420 (40%), Positives = 234/420 (55%), Gaps = 29/420 (6%)

Query: 8   PLQQLLLPVLLA---CAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTEQPVP 64
           P+ QLLL + L         TG+  +    L   WE   +  QE        L   +P  
Sbjct: 5   PILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQET-------LAAAEPPS 57

Query: 65  G--CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTS-RNGSLFRNCTQDG-WSETFPRPN 120
           G  C G +D   CW  + P       CP +L        G + R C  DG W     R +
Sbjct: 58  GLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWG--LWRDH 115

Query: 121 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH 180
             C     + +   +   L +L+VMYTVGYS SL  LL+AL IL  FRRLHCTRNYIH++
Sbjct: 116 TQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHIN 175

Query: 181 LFVSFILRALSNFIKDAVL------FSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLL 234
           LF SF+LRA +   +D +L           +   +   A C+   ++ QYC+ ANY+WLL
Sbjct: 176 LFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLL 235

Query: 235 VEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASI 294
           VEG+YLH+LL +   SE  + + ++  GWG+PA+FV  W I R+  E+  CW+ N   +I
Sbjct: 236 VEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAI 295

Query: 295 WWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIH 354
           WWIIR P++++ILINF++FI IL IL+ KLRT++ R  +  +  RLARSTL L+PL G+H
Sbjct: 296 WWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRD--YRLRLARSTLTLVPLLGVH 353

Query: 355 YIVFAFSPEDAME-----IQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLR 409
            +VFA   E+         +L FE+ L SFQG +V+VLYCF+N EVQ E+++ W    LR
Sbjct: 354 EVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLR 413


>gi|58530853 growth hormone releasing hormone receptor isoform b
           precursor [Homo sapiens]
          Length = 337

 Score =  254 bits (650), Expect = 8e-68
 Identities = 126/306 (41%), Positives = 178/306 (58%), Gaps = 9/306 (2%)

Query: 32  CDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPR 91
           CD +  L E++  CLQ         LG       C   WD + CWP++  G  V + CP 
Sbjct: 28  CDFITQLREDESACLQAAEEMPNTTLG-------CPATWDGLLCWPTAGSGEWVTLPCPD 80

Query: 92  FLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYS 151
           F    +S +G++ R+CT  GWSE FP   +AC V +   + E+  SY   +K++YTVG+S
Sbjct: 81  FFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEE--SYFSTVKIIYTVGHS 138

Query: 152 SSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAH 211
            S+V L VA+ IL A RRLHC RNY+H  LF +FIL+A + F+KDA LF SDD  +C   
Sbjct: 139 ISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFS 198

Query: 212 RAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVA 271
              CK+ +    +  M N+SWLL E +YL+ LLA +  S R+     V  GWG P +F  
Sbjct: 199 TVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTG 258

Query: 272 LWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRG 331
            W   +   ED+ CWD++  +  WWII+GP++LS+ +NF LF+NI+RIL+RKL   +   
Sbjct: 259 TWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSL 318

Query: 332 NEVSHY 337
           +  S Y
Sbjct: 319 HTQSQY 324


>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
           sapiens]
          Length = 411

 Score =  208 bits (529), Expect = 9e-54
 Identities = 123/359 (34%), Positives = 193/359 (53%), Gaps = 21/359 (5%)

Query: 57  LGTEQPVPGCEGMWDNI-SCWPSSVPGRMVEVECPRF---LRMLTSRNGSLFRNCTQDG- 111
           L  E P   C    D I +CWP S  G +VE  CP +   ++  T+RN   +R C ++G 
Sbjct: 31  LDPEGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNA--YRECLENGT 88

Query: 112 WSETFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLH 171
           W+         C   ++D   +    Y + L V Y +G+  S+  L+ A  +  A R + 
Sbjct: 89  WASKINYSQ--CEPILDDKQRKYDLHYRIALVVNY-LGHCVSVAALVAAFLLFLALRSIR 145

Query: 172 CTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYS 231
           C RN IH +L  +FILR +  F+   V     D    +++   C+ +  +F Y ++ N+ 
Sbjct: 146 CLRNVIHWNLITTFILRNVMWFLLQLV-----DHEVHESNEVWCRCITTIFNYFVVTNFF 200

Query: 232 WLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCW-DINA 290
           W+ VEG YLHT + +++ +ER     F+  GW  P   +  WAI + + E+  CW     
Sbjct: 201 WMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEP 260

Query: 291 NASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPL 350
              + +I +GP+IL +LINF+   NI+RILM KLR   T  +E   Y++  ++TL+L+PL
Sbjct: 261 GDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPL 318

Query: 351 FGIHYIVFAFSP--EDAMEIQ-LFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQW 406
            GI Y++F  +P  +D  +I  ++F   L SFQG  V+V YCF NGEV+  V+K+W +W
Sbjct: 319 LGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRW 377


>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
           [Homo sapiens]
          Length = 415

 Score =  200 bits (509), Expect = 2e-51
 Identities = 121/343 (35%), Positives = 190/343 (55%), Gaps = 24/343 (6%)

Query: 74  SCWPSSVPGRMVEVECPRF---LRMLTSRNGSLFRNCTQDG-WSETFPRPNLA-CGVNVN 128
           +CWP S  G++V   CP F   +R  T+ NG  +R C  +G W+    R N + C   +N
Sbjct: 53  TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNG--YRECLANGSWAA---RVNYSECQEILN 107

Query: 129 DSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILR 188
           +    K H Y + + + Y +G+  SLV LLVA  +    R + C RN IH +L  +FILR
Sbjct: 108 EEKKSKVH-YHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILR 165

Query: 189 ALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISF 248
             + F+    +  S +V   +     C+LV   + Y  + N+ W+  EG YLHT + +++
Sbjct: 166 NATWFVVQLTM--SPEVHQSNV--GWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTY 221

Query: 249 FSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIW--WIIRGPVILSI 306
            ++R     F+  GWG P   +  WAI + + ++  CW       ++  +I +GP+IL +
Sbjct: 222 STDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCW-FGKRPGVYTDYIYQGPMILVL 280

Query: 307 LINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSP---E 363
           LINFI   NI+RILM KLR   T  +E   Y++  ++TL+L+PL GI Y++F  +P   E
Sbjct: 281 LINFIFLFNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDE 338

Query: 364 DAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQW 406
            +  + ++F   L SFQG  V+V YCFLN EV+  ++K+W +W
Sbjct: 339 VSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 381


>gi|5031621 calcitonin receptor-like [Homo sapiens]
          Length = 461

 Score =  189 bits (479), Expect = 6e-48
 Identities = 106/352 (30%), Positives = 181/352 (51%), Gaps = 19/352 (5%)

Query: 66  CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLA--- 122
           C   WD   CW     G      CP + +        + + C QDG     P  N     
Sbjct: 65  CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSE-KVTKICDQDGNWFRHPASNRTWTN 123

Query: 123 ---CGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHM 179
              C VN ++      + + L +     +G+  S+  LL++LGI   F+ L C R  +H 
Sbjct: 124 YTQCNVNTHEKVKTALNLFYLTI-----IGHGLSIASLLISLGIFFYFKSLSCQRITLHK 178

Query: 180 HLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLY 239
           +LF SF+  ++   I    + ++  +   +     CK+   +  Y +  NY W+L EG+Y
Sbjct: 179 NLFFSFVCNSVVTIIHLTAVANNQALVATNP--VSCKVSQFIHLYLMGCNYFWMLCEGIY 236

Query: 240 LHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIR 299
           LHTL+ ++ F+E+++L  +   GWG P I   + AIAR    +  CW I+++  + +II 
Sbjct: 237 LHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCW-ISSDTHLLYIIH 295

Query: 300 GPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFA 359
           GP+  ++L+N    +NI+R+L+ KL+   T   E + Y +  R+TL+L+PL GI +++  
Sbjct: 296 GPICAALLVNLFFLLNIVRVLITKLKV--THQAESNLYMKAVRATLILVPLLGIEFVLIP 353

Query: 360 FSPED--AMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLR 409
           + PE   A E+  +    L  FQGL+V+ ++CF NGEVQ  +++ W Q+ ++
Sbjct: 354 WRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQ 405


>gi|4502547 calcitonin receptor [Homo sapiens]
          Length = 474

 Score =  187 bits (475), Expect = 2e-47
 Identities = 108/351 (30%), Positives = 187/351 (53%), Gaps = 13/351 (3%)

Query: 64  PGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLAC 123
           P C   WD   CW  +  G +    CP +          + + C + G     P  N   
Sbjct: 70  PYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSE-KVTKYCDEKGVWFKHPENNRTW 128

Query: 124 G--VNVNDSSNEK-RHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMH 180
                 N  + EK +++Y+L    +  VG+S S+  L+++LGI   FR L C R  +H +
Sbjct: 129 SNYTMCNAFTPEKLKNAYVLYYLAI--VGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKN 186

Query: 181 LFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL 240
           +F+++IL ++   I    +  + ++   D     CK++    QY +  NY W+L EG+YL
Sbjct: 187 MFLTYILNSMIIIIHLVEVVPNGELVRRDP--VSCKILHFFHQYMMACNYFWMLCEGIYL 244

Query: 241 HTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRG 300
           HTL+ ++ F+E++ L+ +   GWG P +   + AI R    +  CW ++    + +II G
Sbjct: 245 HTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW-LSVETHLLYIIHG 303

Query: 301 PVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAF 360
           PV+ ++++NF   +NI+R+L+ K+R  ET   E   Y +  ++T++L+PL GI ++VF +
Sbjct: 304 PVMAALVVNFFFLLNIVRVLVTKMR--ETHEAESHMYLKAVKATMILVPLLGIQFVVFPW 361

Query: 361 SPEDAM--EIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLR 409
            P + M  +I  +   +L  FQG  VA +YCF N EVQ  V+++W Q+ ++
Sbjct: 362 RPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQ 412


>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
           [Homo sapiens]
          Length = 444

 Score =  185 bits (469), Expect = 8e-47
 Identities = 121/372 (32%), Positives = 190/372 (51%), Gaps = 53/372 (14%)

Query: 74  SCWPSSVPGRMVEVECPRF---LRMLTSRNGSLFRNCTQDG-WSETFPRPNLA-CGVNVN 128
           +CWP S  G++V   CP F   +R  T+ NG  +R C  +G W+    R N + C   +N
Sbjct: 53  TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNG--YRECLANGSWAA---RVNYSECQEILN 107

Query: 129 DSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFR-------------------- 168
           +    K H Y + + + Y +G+  SLV LLVA  +    R                    
Sbjct: 108 EEKKSKVH-YHVAVIINY-LGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPW 165

Query: 169 ---------RLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVM 219
                     + C RN IH +L  +FILR  + F+    +  S +V   +     C+LV 
Sbjct: 166 SGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTM--SPEVHQSNV--GWCRLVT 221

Query: 220 VLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHF 279
             + Y  + N+ W+  EG YLHT + +++ ++R     F+  GWG P   +  WAI + +
Sbjct: 222 AAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLY 281

Query: 280 LEDVGCWDINANASIW--WIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHY 337
            ++  CW       ++  +I +GP+IL +LINFI   NI+RILM KLR   T  +E   Y
Sbjct: 282 YDNEKCW-FGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT--SETIQY 338

Query: 338 KRLARSTLLLIPLFGIHYIVFAFSP---EDAMEIQLFFELALGSFQGLVVAVLYCFLNGE 394
           ++  ++TL+L+PL GI Y++F  +P   E +  + ++F   L SFQG  V+V YCFLN E
Sbjct: 339 RKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSE 398

Query: 395 VQLEVQKKWQQW 406
           V+  ++K+W +W
Sbjct: 399 VRSAIRKRWHRW 410


>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
           [Homo sapiens]
          Length = 375

 Score =  184 bits (468), Expect = 1e-46
 Identities = 109/316 (34%), Positives = 175/316 (55%), Gaps = 19/316 (6%)

Query: 102 SLFRNCTQDGWSETFPRPNLACGVNVNDSS---NEKRHS---YLLKLKVMYTVGYSSSLV 155
           SL  N + +G+ E     + A  VN ++     NE++ S   Y + + + Y +G+  SLV
Sbjct: 34  SLASNISDNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLV 92

Query: 156 MLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGC 215
            LLVA  +    R + C RN IH +L  +FILR  + F+    +  S +V   +     C
Sbjct: 93  ALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTM--SPEVHQSNV--GWC 148

Query: 216 KLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAI 275
           +LV   + Y  + N+ W+  EG YLHT + +++ ++R     F+  GWG P   +  WAI
Sbjct: 149 RLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAI 208

Query: 276 ARHFLEDVGCWDINANASIW--WIIRGPVILSILINFILFINILRILMRKLRTQETRGNE 333
            + + ++  CW       ++  +I +GP+IL +LINFI   NI+RILM KLR   T  +E
Sbjct: 209 GKLYYDNEKCW-FGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT--SE 265

Query: 334 VSHYKRLARSTLLLIPLFGIHYIVFAFSP---EDAMEIQLFFELALGSFQGLVVAVLYCF 390
              Y++  ++TL+L+PL GI Y++F  +P   E +  + ++F   L SFQG  V+V YCF
Sbjct: 266 TIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCF 325

Query: 391 LNGEVQLEVQKKWQQW 406
           LN EV+  ++K+W +W
Sbjct: 326 LNSEVRSAIRKRWHRW 341


>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
           [Homo sapiens]
          Length = 401

 Score =  171 bits (433), Expect = 1e-42
 Identities = 112/343 (32%), Positives = 180/343 (52%), Gaps = 38/343 (11%)

Query: 74  SCWPSSVPGRMVEVECPRF---LRMLTSRNGSLFRNCTQDG-WSETFPRPNLA-CGVNVN 128
           +CWP S  G++V   CP F   +R  T+ NG  +R C  +G W+    R N + C   +N
Sbjct: 53  TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNG--YRECLANGSWAA---RVNYSECQEILN 107

Query: 129 DSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILR 188
           +    K H Y + + + Y +G+  SLV LLVA  +    R + C RN IH +L  +FILR
Sbjct: 108 EEKKSKVH-YHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILR 165

Query: 189 ALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISF 248
             + F+    +  S +V   +     C+LV   + Y  + N+ W+  EG YLHT + +++
Sbjct: 166 NATWFVVQLTM--SPEVHQSNV--GWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTY 221

Query: 249 FSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIW--WIIRGPVILSI 306
            ++R     F+  GWG P   +  WAI + + ++  CW       ++  +I +GP+IL +
Sbjct: 222 STDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCW-FGKRPGVYTDYIYQGPMILVL 280

Query: 307 LINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSP---E 363
           LINFI   NI+RILM KLR   T  +E   Y++  ++TL+L+PL GI Y++F  +P   E
Sbjct: 281 LINFIFLFNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDE 338

Query: 364 DAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQW 406
            +  + ++F   L SFQ              V+  ++K+W +W
Sbjct: 339 VSRVVFIYFNSFLESFQ--------------VRSAIRKRWHRW 367


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score = 92.0 bits (227), Expect = 9e-19
 Identities = 68/305 (22%), Positives = 136/305 (44%), Gaps = 17/305 (5%)

Query: 133 EKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNY-IHMHLFVSFILRALS 191
           E    + + L  +  VG S S++ L+  L        +   RN   H+H  +SF +    
Sbjct: 557 ELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAV---- 612

Query: 192 NFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSE 251
             +   +L  S  +   +     C+++ VL  Y  ++ ++W+LVEGL+L++++   F SE
Sbjct: 613 -LVAQVLLLISFRL---EPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSE 668

Query: 252 RKYLQGFVAFGWGSPAI--FVALWAIARHFLEDVGCWDINANASIWWIIRGPVILSILIN 309
               + +   GWG P +   ++L      +     CW   A+ +IW  +  P +  I++N
Sbjct: 669 DSKHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFV-APALFVIVVN 727

Query: 310 FILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQ 369
             + I + R++ +          + S +K  A++  +L+P+ G  ++    +      + 
Sbjct: 728 IGILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVF 787

Query: 370 LFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKASHLE 429
            +    L S QGL + + +C LN EV+   + K + W L        ++ +++ K  H +
Sbjct: 788 QYMFATLNSLQGLFIFLFHCLLNSEVRAAFKHKTKVWSLTS-----SSARTSNAKPFHSD 842

Query: 430 QSQGT 434
              GT
Sbjct: 843 LMNGT 847


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 70/264 (26%), Positives = 111/264 (42%), Gaps = 13/264 (4%)

Query: 140  LKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVL 199
            L L V+  VG   SLV L + +   C  R L   RN IH +L ++  L  L        L
Sbjct: 858  LLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAEL------LFL 911

Query: 200  FSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFV 259
               D   Y       C +   L  Y  +A +SWL +EG++L+ LL   F SE    + + 
Sbjct: 912  VGIDKTQY----EIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYY 967

Query: 260  AFGWGSPAIFVALWAIA--RHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINIL 317
              G+  PA+ V + A    R +  +  CW    N  IW  I GPV   I++N +  +  L
Sbjct: 968  LGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFI-GPVSFVIVVNLVFLMVTL 1026

Query: 318  RILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFELALG 377
              ++R     +   + + + K  A   + L+ L G+ +            +  +      
Sbjct: 1027 HKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFN 1086

Query: 378  SFQGLVVAVLYCFLNGEVQLEVQK 401
            +FQG+ + V +C L  +V  E  K
Sbjct: 1087 AFQGVFIFVFHCALQKKVHKEYSK 1110


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 70/264 (26%), Positives = 111/264 (42%), Gaps = 13/264 (4%)

Query: 140  LKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVL 199
            L L V+  VG   SLV L + +   C  R L   RN IH +L ++  L  L        L
Sbjct: 853  LLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAEL------LFL 906

Query: 200  FSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFV 259
               D   Y       C +   L  Y  +A +SWL +EG++L+ LL   F SE    + + 
Sbjct: 907  VGIDKTQY----EIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYY 962

Query: 260  AFGWGSPAIFVALWAIA--RHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINIL 317
              G+  PA+ V + A    R +  +  CW    N  IW  I GPV   I++N +  +  L
Sbjct: 963  LGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFI-GPVSFVIVVNLVFLMVTL 1021

Query: 318  RILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFELALG 377
              ++R     +   + + + K  A   + L+ L G+ +            +  +      
Sbjct: 1022 HKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFN 1081

Query: 378  SFQGLVVAVLYCFLNGEVQLEVQK 401
            +FQG+ + V +C L  +V  E  K
Sbjct: 1082 AFQGVFIFVFHCALQKKVHKEYSK 1105


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 69/271 (25%), Positives = 123/271 (45%), Gaps = 23/271 (8%)

Query: 142 LKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFS 201
           L ++  VG   SLV L++A+      R +     Y+H+HL V  +L A + F+  A +  
Sbjct: 602 LYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLL-AKTLFL--AGIHK 658

Query: 202 SDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL----HTLLAISFFSERKY-LQ 256
           +D+       + GC ++     Y  +A + W+LVE + L      L  +++FS R   + 
Sbjct: 659 TDN-------KMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKML 711

Query: 257 GFVAFGWGSPAIFVALWAIARHFLEDVG----CWDINANASIWWIIRGPVILSILINFIL 312
              AFG+G P + V + A  +   +  G    CW +N      W   GPV   I+IN +L
Sbjct: 712 HICAFGYGLPMLVVVISASVQP--QGYGMHNRCW-LNTETGFIWSFLGPVCTVIVINSLL 768

Query: 313 FINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFF 372
               L IL ++L +     + +   + L       + + G  +++  F       +  + 
Sbjct: 769 LTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYL 828

Query: 373 ELALGSFQGLVVAVLYCFLNGEVQLEVQKKW 403
              + S QG  + +++C LNG+V+ E  K+W
Sbjct: 829 FTIINSLQGAFIFLIHCLLNGQVR-EEYKRW 858


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 75/302 (24%), Positives = 128/302 (42%), Gaps = 24/302 (7%)

Query: 140  LKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVL 199
            L L V+  VG   SLV L + +   C FR L   RN IH +L ++        FI + + 
Sbjct: 832  LLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINL-------FIAEFIF 884

Query: 200  FSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFV 259
                D T    +   C +   L  +  +A ++W+ +EG+ L+ +L   F SE    + + 
Sbjct: 885  LIGIDKT---KYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYY 941

Query: 260  AFGWGSPAIFVALWAIA--RHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINIL 317
              G+  PA  V + A    + +  +  CW    N  IW  I GPV   IL+N I  +  L
Sbjct: 942  VAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWSFI-GPVTFIILLNIIFLVITL 1000

Query: 318  RILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHY-IVFAFSPEDAMEIQLFFELAL 376
              +++   T +   + + + K        L+ L G+ +     F  E+ + +   F +  
Sbjct: 1001 CKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTI-F 1059

Query: 377  GSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKASHLEQSQGTCR 436
             +FQG+ + + +C L  +V+ E  K ++         H        T++ H      T R
Sbjct: 1060 NAFQGVFIFIFHCALQKKVRKEYGKCFR---------HSYCCGGLPTESPHSSVKASTTR 1110

Query: 437  TS 438
            TS
Sbjct: 1111 TS 1112


>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
           sapiens]
          Length = 652

 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 66/271 (24%), Positives = 122/271 (45%), Gaps = 18/271 (6%)

Query: 142 LKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFS 201
           L V+  VG S SL+ LL+A       + +  T   +H+ L       +L  F+   +   
Sbjct: 356 LTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQL-------SLCLFLAHLLFLV 408

Query: 202 SDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTL---LAISFFSERKYLQGF 258
             D T     +  C ++     Y  +A ++W+L+EG++L      L +  +S    L  +
Sbjct: 409 GIDRT---EPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKW 465

Query: 259 VAF--GWGSPAIFVALWAIARHFLEDVG--CWDINANASIWWIIRGPVILSILINFILFI 314
           + F  G+G PA+ VA+ A +   L      CW ++ +    W   GPV      N +LFI
Sbjct: 466 IMFPVGYGVPAVTVAISAASWPHLYGTADRCW-LHLDQGFMWSFLGPVCAIFSANLVLFI 524

Query: 315 NILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFEL 374
            +  IL RKL +  +  + + + + LA      + + G  + +       A ++  +   
Sbjct: 525 LVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPAAQVMAYLFT 584

Query: 375 ALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQ 405
            + S QG  + ++YC L+ +VQ + QK +++
Sbjct: 585 IINSLQGFFIFLVYCLLSQQVQKQYQKWFRE 615


>gi|23397681 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform a [Homo sapiens]
          Length = 823

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 69/291 (23%), Positives = 130/291 (44%), Gaps = 19/291 (6%)

Query: 142 LKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFS 201
           L V+  +G S SL+ LL+A       + +  T   +H+ L       +L  F+   +   
Sbjct: 536 LTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQL-------SLCLFLAHLLFLV 588

Query: 202 SDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL----HTLLAISFFSERKYLQG 257
           + D T    H+  C ++     Y  +A  +W+L+E LYL      L  +++ S  ++++ 
Sbjct: 589 AIDQT---GHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 645

Query: 258 FV-AFGWGSPAIFVALWAIARHFLEDVG--CWDINANASIWWIIRGPVILSILINFILFI 314
            +   G+G PA+ VA+ A +R  L      CW       IW  + GPV     +N +LF+
Sbjct: 646 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFL-GPVCAIFSVNLVLFL 704

Query: 315 NILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFEL 374
             L IL  +L +  +  + + + + LA      + + G  + +       A  +  +   
Sbjct: 705 VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFT 764

Query: 375 ALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKA 425
            + S QG+ + ++YC L+ +V+ E   KW +   +      + + S+S KA
Sbjct: 765 IINSLQGVFIFLVYCLLSQQVR-EQYGKWSKGIRKLKTESEMHTLSSSAKA 814


>gi|23397693 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform g [Homo sapiens]
          Length = 719

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 69/291 (23%), Positives = 130/291 (44%), Gaps = 19/291 (6%)

Query: 142 LKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFS 201
           L V+  +G S SL+ LL+A       + +  T   +H+ L       +L  F+   +   
Sbjct: 432 LTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQL-------SLCLFLAHLLFLV 484

Query: 202 SDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL----HTLLAISFFSERKYLQG 257
           + D T    H+  C ++     Y  +A  +W+L+E LYL      L  +++ S  ++++ 
Sbjct: 485 AIDQT---GHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 541

Query: 258 FV-AFGWGSPAIFVALWAIARHFLEDVG--CWDINANASIWWIIRGPVILSILINFILFI 314
            +   G+G PA+ VA+ A +R  L      CW       IW  + GPV     +N +LF+
Sbjct: 542 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFL-GPVCAIFSVNLVLFL 600

Query: 315 NILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFEL 374
             L IL  +L +  +  + + + + LA      + + G  + +       A  +  +   
Sbjct: 601 VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFT 660

Query: 375 ALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKA 425
            + S QG+ + ++YC L+ +V+ E   KW +   +      + + S+S KA
Sbjct: 661 IINSLQGVFIFLVYCLLSQQVR-EQYGKWSKGIRKLKTESEMHTLSSSAKA 710


>gi|23397691 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform f [Homo sapiens]
          Length = 763

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 69/291 (23%), Positives = 130/291 (44%), Gaps = 19/291 (6%)

Query: 142 LKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFS 201
           L V+  +G S SL+ LL+A       + +  T   +H+ L       +L  F+   +   
Sbjct: 476 LTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQL-------SLCLFLAHLLFLV 528

Query: 202 SDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL----HTLLAISFFSERKYLQG 257
           + D T    H+  C ++     Y  +A  +W+L+E LYL      L  +++ S  ++++ 
Sbjct: 529 AIDQT---GHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 585

Query: 258 FV-AFGWGSPAIFVALWAIARHFLEDVG--CWDINANASIWWIIRGPVILSILINFILFI 314
            +   G+G PA+ VA+ A +R  L      CW       IW  + GPV     +N +LF+
Sbjct: 586 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFL-GPVCAIFSVNLVLFL 644

Query: 315 NILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFEL 374
             L IL  +L +  +  + + + + LA      + + G  + +       A  +  +   
Sbjct: 645 VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFT 704

Query: 375 ALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKA 425
            + S QG+ + ++YC L+ +V+ E   KW +   +      + + S+S KA
Sbjct: 705 IINSLQGVFIFLVYCLLSQQVR-EQYGKWSKGIRKLKTESEMHTLSSSAKA 754


>gi|23397689 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform e [Homo sapiens]
          Length = 812

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 69/291 (23%), Positives = 130/291 (44%), Gaps = 19/291 (6%)

Query: 142 LKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFS 201
           L V+  +G S SL+ LL+A       + +  T   +H+ L       +L  F+   +   
Sbjct: 525 LTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQL-------SLCLFLAHLLFLV 577

Query: 202 SDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL----HTLLAISFFSERKYLQG 257
           + D T    H+  C ++     Y  +A  +W+L+E LYL      L  +++ S  ++++ 
Sbjct: 578 AIDQT---GHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 634

Query: 258 FV-AFGWGSPAIFVALWAIARHFLEDVG--CWDINANASIWWIIRGPVILSILINFILFI 314
            +   G+G PA+ VA+ A +R  L      CW       IW  + GPV     +N +LF+
Sbjct: 635 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFL-GPVCAIFSVNLVLFL 693

Query: 315 NILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFEL 374
             L IL  +L +  +  + + + + LA      + + G  + +       A  +  +   
Sbjct: 694 VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFT 753

Query: 375 ALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKA 425
            + S QG+ + ++YC L+ +V+ E   KW +   +      + + S+S KA
Sbjct: 754 IINSLQGVFIFLVYCLLSQQVR-EQYGKWSKGIRKLKTESEMHTLSSSAKA 803


>gi|23397687 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform d [Homo sapiens]
          Length = 681

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 69/291 (23%), Positives = 130/291 (44%), Gaps = 19/291 (6%)

Query: 142 LKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFS 201
           L V+  +G S SL+ LL+A       + +  T   +H+ L       +L  F+   +   
Sbjct: 394 LTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQL-------SLCLFLAHLLFLV 446

Query: 202 SDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYL----HTLLAISFFSERKYLQG 257
           + D T    H+  C ++     Y  +A  +W+L+E LYL      L  +++ S  ++++ 
Sbjct: 447 AIDQT---GHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKK 503

Query: 258 FV-AFGWGSPAIFVALWAIARHFLEDVG--CWDINANASIWWIIRGPVILSILINFILFI 314
            +   G+G PA+ VA+ A +R  L      CW       IW  + GPV     +N +LF+
Sbjct: 504 LMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFL-GPVCAIFSVNLVLFL 562

Query: 315 NILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFEL 374
             L IL  +L +  +  + + + + LA      + + G  + +       A  +  +   
Sbjct: 563 VTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFT 622

Query: 375 ALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKA 425
            + S QG+ + ++YC L+ +V+ E   KW +   +      + + S+S KA
Sbjct: 623 IINSLQGVFIFLVYCLLSQQVR-EQYGKWSKGIRKLKTESEMHTLSSSAKA 672


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,781,876
Number of Sequences: 37866
Number of extensions: 737150
Number of successful extensions: 2178
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 1973
Number of HSP's gapped (non-prelim): 87
length of query: 440
length of database: 18,247,518
effective HSP length: 105
effective length of query: 335
effective length of database: 14,271,588
effective search space: 4780981980
effective search space used: 4780981980
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.