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Search of human proteins with 217416390
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
(419 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa... 855 0.0
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 546 e-155
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens] 542 e-154
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens] 474 e-134
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens] 474 e-134
gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens] 360 1e-99
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s... 329 3e-90
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens] 316 2e-86
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 302 4e-82
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ... 271 8e-73
gi|27436871 carboxypeptidase O [Homo sapiens] 242 4e-64
gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens] 187 2e-47
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens] 112 6e-25
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 64 3e-10
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 48 1e-05
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 44 2e-04
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 44 2e-04
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 44 2e-04
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens] 44 4e-04
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 44 4e-04
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 44 4e-04
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 44 4e-04
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 41 0.002
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 40 0.005
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 35 0.097
gi|124001558 ubiquitin specific peptidase 54 [Homo sapiens] 35 0.13
gi|51477714 mannosidase, alpha, class 2A, member 1 [Homo sapiens] 33 0.37
gi|4826960 glutaminyl-tRNA synthetase [Homo sapiens] 31 2.4
gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens] 30 5.3
gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens] 30 5.3
>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
Length = 419
Score = 855 bits (2209), Expect = 0.0
Identities = 419/419 (100%), Positives = 419/419 (100%)
Query: 1 MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTT 60
MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTT
Sbjct: 1 MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTT 60
Query: 61 PGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNF 120
PGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNF
Sbjct: 61 PGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNF 120
Query: 121 GAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHA 180
GAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHA
Sbjct: 121 GAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHA 180
Query: 181 REWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTR 240
REWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTR
Sbjct: 181 REWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTR 240
Query: 241 SKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVK 300
SKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVK
Sbjct: 241 SKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVK 300
Query: 301 AFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQA 360
AFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQA
Sbjct: 301 AFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQA 360
Query: 361 SGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419
SGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY
Sbjct: 361 SGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 546 bits (1406), Expect = e-155
Identities = 266/421 (63%), Positives = 324/421 (76%), Gaps = 4/421 (0%)
Query: 3 MRLILFFGALFGHIYC-LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTP 61
MR ILF GAL G C E F GDQVL I N ++I L QL +L+L+FWKSP++
Sbjct: 1 MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF 60
Query: 62 GETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGN-FNF 120
V VP V++QA K FL SQG+ Y++ IED+Q LLD E++EM N +ERS N FN+
Sbjct: 61 NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNY 120
Query: 121 GAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD--KPAIWLDAGI 178
GAYH+LE I EMDN+ A+ P L +V IG SFENRPM VLKFSTG +PA+WL+AGI
Sbjct: 121 GAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGI 180
Query: 179 HAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRK 238
H+REW++QATA+WTA KIVSDY +DP+ITSIL+ +DIFLLPV NPDGYV++QT+NR+WRK
Sbjct: 181 HSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRK 240
Query: 239 TRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGK 298
TRS+ GS C+G DPNRNW+A F G GAS NPCS+ YHGP ANSEVEVKS+VDFI+ HG
Sbjct: 241 TRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN 300
Query: 299 VKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIY 358
K FI LHSYSQLLM+PYGY K D +EL +VA+ AA++L S+ GT+Y+VGP C+ +Y
Sbjct: 301 FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVY 360
Query: 359 QASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHP 418
ASG SIDW+YD GIK++F FELRDTG YGFLLPA QI+PTAEETWLGLK IMEHVRD+
Sbjct: 361 PASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL 420
Query: 419 Y 419
Y
Sbjct: 421 Y 421
>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
Length = 419
Score = 542 bits (1396), Expect = e-154
Identities = 263/419 (62%), Positives = 320/419 (76%), Gaps = 2/419 (0%)
Query: 3 MRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPG 62
MR +L L G ++ E FVG QVL I ++E Q++ + +LE EHLQLDFW+ P PG
Sbjct: 1 MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPG 60
Query: 63 ETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGN-FNFG 121
VRVPF ++QAVK+FLES GI+Y MIEDVQ LLD+E E+M R R RS + FN+
Sbjct: 61 SPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYA 120
Query: 122 AYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-PAIWLDAGIHA 180
YHTLEEI +D LVAE+P LVSK+ IG+++E RP+ VLKFSTGG K PAIW+D GIH+
Sbjct: 121 TYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHS 180
Query: 181 REWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTR 240
REWVTQA+ +W A KI DYG+D + T+ILD LDIFL VTNPDG+ F+ + NRMWRKTR
Sbjct: 181 REWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTR 240
Query: 241 SKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVK 300
S +GSLC+GVDPNRNWDAGFG GASSNPCS++YHG ANSEVEVKSIVDF+K HG +K
Sbjct: 241 SHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIK 300
Query: 301 AFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQA 360
AFI++HSYSQLLM+PYGYK + D DEL ++++ A +L SL+GTK+ G I IYQA
Sbjct: 301 AFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQA 360
Query: 361 SGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419
SG +IDW+Y GIKYSF FELRDTGRYGFLLPA QI+PTA+ETWL L IMEH +HPY
Sbjct: 361 SGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY 419
>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 474 bits (1220), Expect = e-134
Identities = 225/418 (53%), Positives = 305/418 (72%), Gaps = 2/418 (0%)
Query: 4 RLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGE 63
R +L F + F GDQVL ++ +E+Q+ L LE + ++DFW+ P P
Sbjct: 19 RTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSL 78
Query: 64 TAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGN-FNFGA 122
+RVPF ++ +K +LES G+AYSIMI+D+QVLLD+E + M +RR ERS N F++ +
Sbjct: 79 PVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSS 138
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-PAIWLDAGIHAR 181
YHTLEEI +DN V EH +VSK+ IG+SFEN+ + VLKFSTGG + PAIW+D GIH+R
Sbjct: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSR 198
Query: 182 EWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRS 241
EW+T AT +WTANKIVSDYGKD +T IL+A+DIF+ VTNPDG+ F+ + NR+WRK +S
Sbjct: 199 EWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKS 258
Query: 242 KVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKA 301
G C+GVD NRNW +GFGG G++SNPCS++YHGPS SE EV +IV+FI +HG KA
Sbjct: 259 IRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKA 318
Query: 302 FITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQAS 361
I++HSYSQ+LM+PYG + + EL ++A+ A ++L +HG +Y G I + +Y AS
Sbjct: 319 LISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYVAS 378
Query: 362 GGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419
G ++DW+YD GIKY+F+FELRDTG+YGFLLPA QI+PTA+ETW+ L+ IMEH +HPY
Sbjct: 379 GITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHPY 436
>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 474 bits (1220), Expect = e-134
Identities = 225/418 (53%), Positives = 305/418 (72%), Gaps = 2/418 (0%)
Query: 4 RLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGE 63
R +L F + F GDQVL ++ +E+Q+ L LE + ++DFW+ P P
Sbjct: 19 RTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSL 78
Query: 64 TAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGN-FNFGA 122
+RVPF ++ +K +LES G+AYSIMI+D+QVLLD+E + M +RR ERS N F++ +
Sbjct: 79 PVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSS 138
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-PAIWLDAGIHAR 181
YHTLEEI +DN V EH +VSK+ IG+SFEN+ + VLKFSTGG + PAIW+D GIH+R
Sbjct: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSR 198
Query: 182 EWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRS 241
EW+T AT +WTANKIVSDYGKD +T IL+A+DIF+ VTNPDG+ F+ + NR+WRK +S
Sbjct: 199 EWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKS 258
Query: 242 KVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKA 301
G C+GVD NRNW +GFGG G++SNPCS++YHGPS SE EV +IV+FI +HG KA
Sbjct: 259 IRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKA 318
Query: 302 FITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQAS 361
I++HSYSQ+LM+PYG + + EL ++A+ A ++L +HG +Y G I + +Y AS
Sbjct: 319 LISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYVAS 378
Query: 362 GGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419
G ++DW+YD GIKY+F+FELRDTG+YGFLLPA QI+PTA+ETW+ L+ IMEH +HPY
Sbjct: 379 GITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHPY 436
>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
Length = 403
Score = 360 bits (924), Expect = 1e-99
Identities = 172/316 (54%), Positives = 230/316 (72%), Gaps = 2/316 (0%)
Query: 4 RLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGE 63
R +L F + F GDQVL ++ +E+Q+ L LE + ++DFW+ P P
Sbjct: 19 RTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSL 78
Query: 64 TAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGN-FNFGA 122
+RVPF ++ +K +LES G+AYSIMI+D+QVLLD+E + M +RR ERS N F++ +
Sbjct: 79 PVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSS 138
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-PAIWLDAGIHAR 181
YHTLEEI +DN V EH +VSK+ IG+SFEN+ + VLKFSTGG + PAIW+D GIH+R
Sbjct: 139 YHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSR 198
Query: 182 EWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRS 241
EW+T AT +WTANKIVSDYGKD +T IL+A+DIF+ VTNPDG+ F+ + NR+WRK +S
Sbjct: 199 EWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKS 258
Query: 242 KVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKA 301
G C+GVD NRNW +GFGG G++SNPCS++YHGPS SE EV +IV+FI +HG KA
Sbjct: 259 IRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKA 318
Query: 302 FITLHSYSQLLMFPYG 317
I++HSYSQ+LM+PYG
Sbjct: 319 LISIHSYSQMLMYPYG 334
>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
Length = 417
Score = 329 bits (843), Expect = 3e-90
Identities = 172/425 (40%), Positives = 259/425 (60%), Gaps = 14/425 (3%)
Query: 1 MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTT 60
M L+L AL + E F G++V + +E I + +L + Q+DFWK +
Sbjct: 1 MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTT--QIDFWKPDSV 58
Query: 61 ----PGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSG 116
P T RV + V+ L+ + Y ++I +++ +++ + + R R+
Sbjct: 59 TQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDS------RVRAT 112
Query: 117 NFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGG-DKPAIWLD 175
++ Y+ E I + E+P L+S+ IG++FE R + +LK G +KPAI++D
Sbjct: 113 GHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMD 172
Query: 176 AGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRM 235
G HAREW++ A W + V YG++ +T +LD LD ++LPV N DGY+++ TK+R
Sbjct: 173 CGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRF 232
Query: 236 WRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS 295
WRKTRS +GS C+G DPNRN+DAG+ GAS NPC ++Y GP+A SE E K++ DFI++
Sbjct: 233 WRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRN 292
Query: 296 H-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPIC 354
+KA++T+HSYSQ++++PY Y ++ EL+ +A+ + L SLHGTKY GP
Sbjct: 293 KLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGA 352
Query: 355 SVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414
+ IY A+GGS DW+YD GI+YSF FELRDTGRYGFLLP QI T EET+L +K + +V
Sbjct: 353 TTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYV 412
Query: 415 RDHPY 419
+H Y
Sbjct: 413 LEHLY 417
>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
Length = 437
Score = 316 bits (810), Expect = 2e-86
Identities = 163/406 (40%), Positives = 243/406 (59%), Gaps = 10/406 (2%)
Query: 15 HIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWK----SPTTPGETAHVRVP 70
H+Y + GD+V+ +P EE+ L ++ Q L++D W+ S + G V +P
Sbjct: 31 HLYN-NRYAGDKVIRFIPKTEEEAYALKKISYQ--LKVDLWQPSSISYVSEGTVTDVHIP 87
Query: 71 FVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEIS 130
+A+ FL+ I Y ++IED+Q L+K + RR SG +N+ YH+LEEI
Sbjct: 88 QNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSG-YNYEVYHSLEEIQ 146
Query: 131 QEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-KPAIWLDAGIHAREWVTQATA 189
M +L H GL+ +IG S+E R + +LK K A+W+D GIHAREW+ A
Sbjct: 147 NWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFC 206
Query: 190 LWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCV 249
W + + Y DP++ +L+ L +++PV N DGY FS T +R WRKTRS+ S C
Sbjct: 207 QWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCR 266
Query: 250 GVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGK-VKAFITLHSY 308
GVD NRNW + GAS +PC D+Y GP SE EVK++ +F++ H K ++A+++ H+Y
Sbjct: 267 GVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAY 326
Query: 309 SQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWS 368
+Q+L++PY YK + +F + A KA +L+S++G +Y+ GP + +Y +SG S+DW+
Sbjct: 327 AQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWA 386
Query: 369 YDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414
Y GI Y+FAFELRDTG +GFLLP I PT ET L +K I H+
Sbjct: 387 YKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHL 432
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 302 bits (773), Expect = 4e-82
Identities = 164/426 (38%), Positives = 254/426 (59%), Gaps = 22/426 (5%)
Query: 3 MRLILFFGALFGHIYCLET-FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTP 61
MRLIL G + + F ++V + P +E+Q + L +LDFW P
Sbjct: 1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTN--ELDFWY----P 54
Query: 62 GETAHV--------RVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRE 113
G T HV RV QA++ L+ + Y I+I D+Q ++K+ F+ + +
Sbjct: 55 GATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQ-----FDVKED 109
Query: 114 RSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-PAI 172
G ++ Y+ E+I + ++ ++P +VS++ IGS+ E+ P+ VLK ++ AI
Sbjct: 110 IPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAI 169
Query: 173 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 232
+ D GIHAREWV+ A W + YG++ +T +LD ++ ++LPV N DGY++S TK
Sbjct: 170 FTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTK 229
Query: 233 NRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDF 292
NRMWRK RSK S C+G D NRN++A + +++PC+D+Y G + SE E K++ +F
Sbjct: 230 NRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNF 289
Query: 293 IKSH-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVG 351
I+SH ++K +IT HSYSQ+L+FPYGY + ++L++VA+ L + + T+Y G
Sbjct: 290 IRSHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYG 349
Query: 352 PICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIM 411
PI S IY SG S+DW+YD GIK++FAFELRD G++GFLLP +I PT ET L +K I
Sbjct: 350 PIESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIA 409
Query: 412 EHVRDH 417
+++ H
Sbjct: 410 KYILKH 415
>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
Length = 423
Score = 271 bits (693), Expect = 8e-73
Identities = 158/402 (39%), Positives = 226/402 (56%), Gaps = 14/402 (3%)
Query: 22 FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTP----GETAHVRVPFVNVQAV 77
F QVL +P Q++ L L + L W+ T + H V +V V
Sbjct: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNV 80
Query: 78 KVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLV 137
K L GI S+++ DV+ L+ ++ + R S + YH+L EI ++ +
Sbjct: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS---YYEQYHSLNEIYSWIEFIT 137
Query: 138 AEHPGLVSKVNIGSSFENRPMNVLKFS--TGGDKPAIWLDAGIHAREWVTQATALWTANK 195
HP +++K++IGSSFE P+ VLK S K AIW+D GIHAREW++ A LW
Sbjct: 138 ERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGH 197
Query: 196 IVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNR 255
I YG T++L +D +++PV N DGY +S KNRMWRK RS + + C+G D NR
Sbjct: 198 ITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNR 257
Query: 256 NW-DAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLM 313
N+ + GASS+ CS++Y G SE EVK++ F++ + ++KA+I++HSYSQ ++
Sbjct: 258 NFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIV 317
Query: 314 FPYGYKCTKLDDFDELSEVAQKAAQSL-RSLHGTKYKVGPICSVIYQASGGSIDWSYDYG 372
FPY Y +K D +ELS VA +A +++ ++ T+Y G +Y A GG DW YD G
Sbjct: 318 FPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLG 377
Query: 373 IKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414
IKYSF ELRDTG YGFLLP R I PT E + + I HV
Sbjct: 378 IKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHV 419
>gi|27436871 carboxypeptidase O [Homo sapiens]
Length = 374
Score = 242 bits (618), Expect = 4e-64
Identities = 119/300 (39%), Positives = 185/300 (61%), Gaps = 3/300 (1%)
Query: 118 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFS--TGGDKPAIWLD 175
+++ YH + EI + M + ++ +V++ +G ++E PM LK S +G K IW+D
Sbjct: 45 YSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMD 104
Query: 176 AGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRM 235
GIHAREW+ A W +I+ ++ + SI +L LD ++LPV N DGY+++ T +R+
Sbjct: 105 CGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRL 164
Query: 236 WRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS 295
WRK+RS + C G D NRN++A + GAS N ++ G SE E K++ FI+S
Sbjct: 165 WRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIES 224
Query: 296 H-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPIC 354
+ F+T+HSY QL++ PYGY K + E+ +V QKAA +L++ +GT Y+VG
Sbjct: 225 KKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSA 284
Query: 355 SVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414
++Y +SG S DW+ D GI +S+ FELRD+G YGF+LP QI PT EET + ++++ V
Sbjct: 285 DILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDV 344
>gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]
Length = 360
Score = 187 bits (474), Expect = 2e-47
Identities = 123/364 (33%), Positives = 183/364 (50%), Gaps = 51/364 (14%)
Query: 22 FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTP----GETAHVRVPFVNVQAV 77
F QVL +P Q++ L L + L W+ T + H V +V V
Sbjct: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNV 80
Query: 78 KVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLV 137
K L GI S+++ DV+ L+ ++ + R S + YH+L EI ++ +
Sbjct: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS---YYEQYHSLNEIYSWIEFIT 137
Query: 138 AEHPGLVSKVNIGSSFENRPMNVLKFS--TGGDKPAIWLDAGIHAREWVTQATALWTANK 195
HP +++K++IGSSFE P+ VLK S K AIW+D GIHAREW++ A LW
Sbjct: 138 ERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGH 197
Query: 196 IVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNR 255
NRMWRK RS + + C+G D NR
Sbjct: 198 -------------------------------------NRMWRKNRSFYANNHCIGTDLNR 220
Query: 256 NWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLM 313
N+ + + GASS+ CS++Y G SE EVK++ F++ + ++KA+I++HSYSQ ++
Sbjct: 221 NFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIV 280
Query: 314 FPYGYKCTKLDDFDELSEVAQKAAQSL-RSLHGTKYKVGPICSVIYQASGGSIDWSYDYG 372
FPY Y +K D +ELS VA +A +++ ++ T+Y G +Y A GG DW YD G
Sbjct: 281 FPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLG 340
Query: 373 IKYS 376
IKYS
Sbjct: 341 IKYS 344
>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
Length = 193
Score = 112 bits (280), Expect = 6e-25
Identities = 55/126 (43%), Positives = 75/126 (59%), Gaps = 1/126 (0%)
Query: 133 MDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-KPAIWLDAGIHAREWVTQATALW 191
M +L H GL+ +IG S+E R + +LK K A+W+D GIHAREW+ A W
Sbjct: 1 MHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQW 60
Query: 192 TANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGV 251
+ + Y DP++ +L+ L +++PV N DGY FS T +R WRKTRS+ S C GV
Sbjct: 61 FVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGV 120
Query: 252 DPNRNW 257
D NRNW
Sbjct: 121 DANRNW 126
Score = 68.6 bits (166), Expect = 1e-11
Identities = 32/55 (58%), Positives = 39/55 (70%)
Query: 360 ASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414
+SG S+DW+Y GI Y+FAFELRDTG +GFLLP I PT ET L +K I H+
Sbjct: 134 SSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHL 188
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 63.9 bits (154), Expect = 3e-10
Identities = 53/227 (23%), Positives = 100/227 (44%), Gaps = 30/227 (13%)
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFS-----TGGDKPAIWLDAG 177
YH+ +++S+ + LV +P + + N+G S E R + L+ S + ++P I AG
Sbjct: 933 YHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAG 992
Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237
IH V L A + +Y K+P++T ++D I ++P NPDG +Q K+
Sbjct: 993 IHGNAPVGTELLLALAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKD---- 1048
Query: 238 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHG 297
SK+ + G D + ++ + S+ E K+I++ +
Sbjct: 1049 -CTSKIGQTNARGKDLDTDF--------------------TNNASQPETKAIIENLIQKQ 1087
Query: 298 KVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLH 344
+ L S L+ +PY +++ + L +A A + S+H
Sbjct: 1088 DFSLSVALDGGSMLVTYPYDKPVQTVENKETLKHLASLYANNHPSMH 1134
Score = 61.6 bits (148), Expect = 1e-09
Identities = 74/319 (23%), Positives = 118/319 (36%), Gaps = 86/319 (26%)
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTG-------GD------- 168
YH E S + A PGL +IG S E RP+ VL+ + G GD
Sbjct: 59 YHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAG 118
Query: 169 ----------KPAIWLDAGIHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFL 217
+P + L +H E V++ ++ A ++ + Y + DP + +L+ D++L
Sbjct: 119 PDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYL 178
Query: 218 LPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHG 277
LP NPDG+ + R D GFG G S D+ G
Sbjct: 179 LPSLNPDGF-------------------------ERAREGDCGFGDGGPSGASGRDNSRG 213
Query: 278 ---------------PSANSEV-EVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYG---- 317
P A EV EV++++++I+ K LH S + +P+
Sbjct: 214 RDLNRSFPDQFSTGEPPALDEVPEVRALIEWIR-RNKFVLSGNLHGGSVVASYPFDDSPE 272
Query: 318 YKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPIC---------------SVIYQASG 362
+K T + EV + A++ S H P C + Y G
Sbjct: 273 HKATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEG 332
Query: 363 GSIDWSYDYGIKYSFAFEL 381
G D++Y + + EL
Sbjct: 333 GMQDYNYVWANCFEITLEL 351
Score = 48.5 bits (114), Expect = 1e-05
Identities = 54/269 (20%), Positives = 106/269 (39%), Gaps = 42/269 (15%)
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAIWLDAG 177
+H ++ + E+P + ++G S E+R + V++ S +P
Sbjct: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237
+H E V + L + ++G DP +T ++ I L+P NPDGY SQ + +
Sbjct: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSI-- 620
Query: 238 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHG 297
S + + D NRN+ D + + ++ E +++ ++KS+
Sbjct: 621 ---SVIGRNNSNNFDLNRNF--------------PDQFVQITDPTQPETIAVMSWMKSYP 663
Query: 298 KVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSE--VAQKAAQSLRSLHGTKYKVGPICS 355
V + LH S ++ +P+ L + + + V Q+ A S + ++ P +
Sbjct: 664 FVLS-ANLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQQIALSYSKENSQMFQGRPCKN 722
Query: 356 VI---------------YQASGGSIDWSY 369
+ Y GG DW+Y
Sbjct: 723 MYPNEYFPHGITNGASWYNVPGGMQDWNY 751
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
Length = 458
Score = 48.1 bits (113), Expect = 1e-05
Identities = 47/209 (22%), Positives = 91/209 (43%), Gaps = 22/209 (10%)
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAIWLDAG 177
+H +++ + + + E PG+ +IG S E R + VL+FS +P +
Sbjct: 25 HHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGN 84
Query: 178 IHAREWVTQATALWTANKIVSDY-GKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMW 236
+H E + + L + + ++ ++ I ++ I +LP NPDGY + +
Sbjct: 85 MHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGP-- 142
Query: 237 RKTRSKVSGSLCVGVDPNRN---------WDAGFGGPGASSNPCSDSYHGPSANSEVEVK 287
K V + GVD NRN ++ +GGP P D++ + E E +
Sbjct: 143 NKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN-HHLPLPDNW---KSQVEPETR 198
Query: 288 SIVDFIKSHGKVKAFITLHSYSQLLMFPY 316
+++ ++ S V + LH + + +PY
Sbjct: 199 AVIRWMHSFNFVLS-ANLHGGAVVANYPY 226
>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
Length = 515
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 6/111 (5%)
Query: 122 AYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDA 176
++H+ ++ + + + + +IG SF+ R + V++FS+ + P + L
Sbjct: 49 SHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIG 108
Query: 177 GIHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFLLPVTNPDGY 226
IH E + ++ A + S+Y +P I +L+ I LLP NPDGY
Sbjct: 109 NIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGY 159
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 6/111 (5%)
Query: 122 AYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDA 176
++H+ ++ + + + + +IG SF+ R + V++FS+ + P + L
Sbjct: 175 SHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIG 234
Query: 177 GIHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFLLPVTNPDGY 226
IH E + ++ A + S+Y +P I +L+ I LLP NPDGY
Sbjct: 235 NIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGY 285
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 6/111 (5%)
Query: 122 AYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDA 176
++H+ ++ + + + + +IG SF+ R + V++FS+ + P + L
Sbjct: 186 SHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIG 245
Query: 177 GIHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFLLPVTNPDGY 226
IH E + ++ A + S+Y +P I +L+ I LLP NPDGY
Sbjct: 246 NIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGY 296
>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
Length = 476
Score = 43.5 bits (101), Expect = 4e-04
Identities = 35/154 (22%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Query: 110 RRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTG--- 166
RR ++ +F YH E+ + + ++ + + +G SFE R + V++ S
Sbjct: 41 RRLQQEDGISF-EYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGV 99
Query: 167 --GDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFLLPVTNP 223
+P +H E V + ++ A + ++Y K + +I +++ + I ++P NP
Sbjct: 100 HEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNP 159
Query: 224 DGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNW 257
DG F + ++ V S G+D NRN+
Sbjct: 160 DG--FEKAASQPGELKDWFVGRSNAQGIDLNRNF 191
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 5/109 (4%)
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLD-----AG 177
YH E + + + + + +IG S + R + VL + I + A
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGY 226
+H E V + L + +V+ GKDP IT+++++ I ++P NPDG+
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 5/109 (4%)
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLD-----AG 177
YH E + + + + + +IG S + R + VL + I + A
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGY 226
+H E V + L + +V+ GKDP IT+++++ I ++P NPDG+
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 5/109 (4%)
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLD-----AG 177
YH E + + + + + +IG S + R + VL + I + A
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGY 226
+H E V + L + +V+ GKDP IT+++++ I ++P NPDG+
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 40.8 bits (94), Expect = 0.002
Identities = 46/216 (21%), Positives = 89/216 (41%), Gaps = 28/216 (12%)
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDAG 177
+H + + + M + + P + +IG S++ + V++ S + P + AG
Sbjct: 299 HHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAG 358
Query: 178 IHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFLLPVTNPDGYVFSQTKNRM- 235
+H E + + L + ++ + +P +T +L + I LLP NPDGY + +
Sbjct: 359 MHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSEL 418
Query: 236 --WRKTRSKVSGSLCVGVDPNRN--------WDAGFGG--PGASSN---PCSDSYHGPSA 280
W + R +D N N W+A G P N P Y P+A
Sbjct: 419 VGWAEGRWNNQ-----SIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNA 473
Query: 281 NSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPY 316
E ++++ ++K V + LH ++ +P+
Sbjct: 474 TVAPETRAVIKWMKRIPFVLS-ANLHGGELVVSYPF 508
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 39.7 bits (91), Expect = 0.005
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 26/236 (11%)
Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDAG 177
+H+ +++ Q M + E P + ++G S + ++ S + P AG
Sbjct: 564 HHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYTAG 623
Query: 178 IHAREWVTQATALWTANKIVSDYGK-DPSITSILDALDIFLLPVTNPDGY--------VF 228
IH E + + L + +Y +P + S++ I L+P NPDGY F
Sbjct: 624 IHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGSEF 683
Query: 229 SQTKNRMWRKTRSKV------SGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANS 282
+W + + S+ G + R W + P ++ P + Y P A
Sbjct: 684 GNWALGLWTEEGFDIFEDFPDLNSVLWGAE-ERKW-VPYRVPN-NNLPIPERYLSPDATV 740
Query: 283 EVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQ 338
EV++I+ +++ + V L+ +L+ +PY T ++L A AA+
Sbjct: 741 STEVRAIIAWMEKNPFVLG-ANLNGGERLVSYPYDMARTPTQ--EQLLAAAMAAAR 793
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 35.4 bits (80), Expect = 0.097
Identities = 29/126 (23%), Positives = 53/126 (42%), Gaps = 7/126 (5%)
Query: 108 FNRRRERSGNFNFG-AYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTG 166
++RR E + + +H +E+ Q M + P + NIG S + + ++ S
Sbjct: 302 YHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDH 361
Query: 167 GDK-----PAIWLDAGIHAREWVTQATALWTANKIVSDY-GKDPSITSILDALDIFLLPV 220
+ P AG H E + + L + +Y ++ I +++ I +LP
Sbjct: 362 PGEHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPS 421
Query: 221 TNPDGY 226
NPDGY
Sbjct: 422 LNPDGY 427
>gi|124001558 ubiquitin specific peptidase 54 [Homo sapiens]
Length = 1684
Score = 35.0 bits (79), Expect = 0.13
Identities = 37/168 (22%), Positives = 74/168 (44%), Gaps = 28/168 (16%)
Query: 105 EMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFS 164
E L ++ R+ + + + L + + + N++ P L S+ N+GS R
Sbjct: 484 ETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGR-------- 535
Query: 165 TGGDKP--AIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTN 222
GGD+P +H+R+W ++T+ + + S Y P+ ++L+I
Sbjct: 536 -GGDQPDKKPPRTLPLHSRDWEIESTSSESKSSSSSKY--RPTWRPKRESLNI------- 585
Query: 223 PDGYVFSQTKNRMWRKTR----SKVSGSLCVGVDPNR--NWDAGFGGP 264
+FS+ K + T+ S+ S + +P++ ++D FGGP
Sbjct: 586 --DSIFSKDKRKHCGYTQLSPFSEDSAKEFIPDEPSKPPSYDIKFGGP 631
>gi|51477714 mannosidase, alpha, class 2A, member 1 [Homo sapiens]
Length = 1144
Score = 33.5 bits (75), Expect = 0.37
Identities = 36/149 (24%), Positives = 62/149 (41%), Gaps = 19/149 (12%)
Query: 88 YSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSK- 146
+ ++I + ++LD+ + + + R R G+F G L+E ++ L+AE+ ++S
Sbjct: 15 FCVVIFSLYLMLDRGHLD--YPRNPRREGSFPQGQLSMLQEKIDHLERLLAENNEIISNI 72
Query: 147 ----VNIGSSFENRP-MNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYG 201
+N+ S E+ P + FS G AG H + S G
Sbjct: 73 RDSVINLSESVEDGPKSSQSNFSQG---------AGSHLLPSQLSLSVDTADCLFASQSG 123
Query: 202 KDPSITSILDALDIFLLPVTNPDGYVFSQ 230
S +LD L+ NPDG V+ Q
Sbjct: 124 SHNSDVQMLDVYS--LISFDNPDGGVWKQ 150
>gi|4826960 glutaminyl-tRNA synthetase [Homo sapiens]
Length = 775
Score = 30.8 bits (68), Expect = 2.4
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 326 FDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTG 385
F L QKA ++L++ ++ + Q G +ID + + Y A LRDT
Sbjct: 10 FTSLGLSEQKARETLKN-SALSAQLREAATQAQQTLGSTIDKATGI-LLYGLASRLRDTR 67
Query: 386 RYGFLLPARQILPTAEETWLGLKAIMEHVRDHP 418
R FL+ I T L A +E+VR HP
Sbjct: 68 RLSFLV--SYIASKKIHTEPQLSAALEYVRSHP 98
>gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens]
Length = 676
Score = 29.6 bits (65), Expect = 5.3
Identities = 30/137 (21%), Positives = 59/137 (43%), Gaps = 9/137 (6%)
Query: 26 QVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAH--VRVPFVNVQAVKVFL-- 81
++ E V + EQ + + +LE Q+ + + P G H ++P +A +F
Sbjct: 425 RITEAVATATEQRELIARLE-QDLSIIQSIQRPDAEGAAEHRLEKIPEPIKEATALFYGP 483
Query: 82 --ESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAE 139
+ G ++ + ++ + E F R + N A HTL+ + E+D+L A+
Sbjct: 484 AAPASGALPEGQVDSLLSIISSQRER--FRARNQELEAENRLAQHTLQALQSELDSLRAD 541
Query: 140 HPGLVSKVNIGSSFENR 156
+ L K+ S+ R
Sbjct: 542 NIKLFEKIKFLQSYPGR 558
>gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens]
Length = 678
Score = 29.6 bits (65), Expect = 5.3
Identities = 30/137 (21%), Positives = 59/137 (43%), Gaps = 9/137 (6%)
Query: 26 QVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAH--VRVPFVNVQAVKVFL-- 81
++ E V + EQ + + +LE Q+ + + P G H ++P +A +F
Sbjct: 427 RITEAVATATEQRELIARLE-QDLSIIQSIQRPDAEGAAEHRLEKIPEPIKEATALFYGP 485
Query: 82 --ESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAE 139
+ G ++ + ++ + E F R + N A HTL+ + E+D+L A+
Sbjct: 486 AAPASGALPEGQVDSLLSIISSQRER--FRARNQELEAENRLAQHTLQALQSELDSLRAD 543
Query: 140 HPGLVSKVNIGSSFENR 156
+ L K+ S+ R
Sbjct: 544 NIKLFEKIKFLQSYPGR 560
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,210,887
Number of Sequences: 37866
Number of extensions: 694795
Number of successful extensions: 1783
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1719
Number of HSP's gapped (non-prelim): 35
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.