Search of human proteins with 21702735

Search of human proteins with 21702735

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21702735 ADP-ribosylhydrolase like 1 isoform 1 [Homo
sapiens]
         (354 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21702735 ADP-ribosylhydrolase like 1 isoform 1 [Homo sapiens]      740   0.0  
gi|40316946 ADP-ribosylhydrolase like 1 isoform 2 [Homo sapiens]      573   e-164
gi|4557263 ADP-ribosylarginine hydrolase [Homo sapiens]               309   2e-84
gi|8923417 ADP-ribosylhydrolase like 2 [Homo sapiens]                  50   3e-06
gi|41352061 metalloprotease 1 [Homo sapiens]                           32   0.66 
gi|154448890 THO complex 1 [Homo sapiens]                              30   3.3  
gi|4885487 myeloid leukemia factor 2 [Homo sapiens]                    30   4.3  
gi|9789865 eukaryotic translation initiation factor 4E nuclear i...    29   5.6  
gi|13699818 cytochrome P450, family 2, subfamily C, polypeptide ...    28   9.5  
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...    28   9.5  
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi...    28   9.5  

>gi|21702735 ADP-ribosylhydrolase like 1 isoform 1 [Homo sapiens]
          Length = 354

 Score =  740 bits (1911), Expect = 0.0
 Identities = 354/354 (100%), Positives = 354/354 (100%)

Query: 1   MEKFKAAMLLGSVGDALGYRNVCKENSTVGMKIQEELQRSGGLDHLVLSPGEWPVSDNTI 60
           MEKFKAAMLLGSVGDALGYRNVCKENSTVGMKIQEELQRSGGLDHLVLSPGEWPVSDNTI
Sbjct: 1   MEKFKAAMLLGSVGDALGYRNVCKENSTVGMKIQEELQRSGGLDHLVLSPGEWPVSDNTI 60

Query: 61  MHIATAEALTTDYWCLDDLYREMVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWH 120
           MHIATAEALTTDYWCLDDLYREMVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWH
Sbjct: 61  MHIATAEALTTDYWCLDDLYREMVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWH 120

Query: 121 TPFNEKGSGFGAATKAMCIGLRYWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFV 180
           TPFNEKGSGFGAATKAMCIGLRYWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFV
Sbjct: 121 TPFNEKGSGFGAATKAMCIGLRYWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFV 180

Query: 181 SFAAQGKPLVQWGRDMLRAVPLAEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKD 240
           SFAAQGKPLVQWGRDMLRAVPLAEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKD
Sbjct: 181 SFAAQGKPLVQWGRDMLRAVPLAEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKD 240

Query: 241 SENKAIFPDNYDAEEREKTYRKWSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMF 300
           SENKAIFPDNYDAEEREKTYRKWSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMF
Sbjct: 241 SENKAIFPDNYDAEEREKTYRKWSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMF 300

Query: 301 HGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK 354
           HGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK
Sbjct: 301 HGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK 354


>gi|40316946 ADP-ribosylhydrolase like 1 isoform 2 [Homo sapiens]
          Length = 272

 Score =  573 bits (1477), Expect = e-164
 Identities = 272/272 (100%), Positives = 272/272 (100%)

Query: 83  MVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLR 142
           MVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLR
Sbjct: 1   MVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGLR 60

Query: 143 YWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPL 202
           YWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPL
Sbjct: 61  YWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPL 120

Query: 203 AEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRK 262
           AEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRK
Sbjct: 121 AEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYRK 180

Query: 263 WSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGL 322
           WSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGL
Sbjct: 181 WSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRAMFHGGESAATGTIAGCLFGLLYGL 240

Query: 323 DLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK 354
           DLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK
Sbjct: 241 DLVPKGLYQDLEDKEKLEDLGAALYRLSTEEK 272


>gi|4557263 ADP-ribosylarginine hydrolase [Homo sapiens]
          Length = 357

 Score =  309 bits (792), Expect = 2e-84
 Identities = 163/355 (45%), Positives = 224/355 (63%), Gaps = 6/355 (1%)

Query: 1   MEKFKAAMLLGSVGDALGYRNVCKENSTVGMKIQEELQRSGGLDHLVLSPGEWPVSDNTI 60
           MEK+ AAM+L + GDALGY N   E    G KI  +L + GGLD   L  G W VSD+T+
Sbjct: 1   MEKYVAAMVLSAAGDALGYYNGKWEFLQDGEKIHRQLAQLGGLD--ALDVGRWRVSDDTV 58

Query: 61  MHIATAEALTTDYWC--LDDLYREMVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYLLA 118
           MH+ATAEAL        L  LY  + + Y + +E +  R P  A++    QLKP      
Sbjct: 59  MHLATAEALVEAGKAPKLTQLYYLLAKHYQDCMEDMDGRAPGGASVHNAMQLKPGKPN-G 117

Query: 119 WHTPFNEKGSGFGAATKAMCIGLRYWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTAL 178
           W  PFN    G GAA +AMCIGLR+    +L+TLI+VS+E GRMTH+HPTG+LG+L +AL
Sbjct: 118 WRIPFNSHEGGCGAAMRAMCIGLRFPHHSQLDTLIQVSIESGRMTHHHPTGYLGALASAL 177

Query: 179 FVSFAAQGKPLVQWGRDMLRAVPLAEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKIS 238
           F ++A   +P +QWG+ ++  +P A++Y  ++     E  +HW YF+ KW+ YL+ R I 
Sbjct: 178 FTAYAVNSRPPLQWGKGLMELLPEAKKYIVQSGYFVEENLQHWSYFQTKWENYLKLRGI- 236

Query: 239 KDSENKAIFPDNYDAEEREKTYRKWSSEGRGGRRGHDAPMIAYDALLAAGNSWTELCHRA 298
            D E+   FP+++  +ER++ Y   S  G GG  GHDAPMIAYDA+LAAG+SW EL HRA
Sbjct: 237 LDGESAPTFPESFGVKERDQFYTSLSYSGWGGSSGHDAPMIAYDAVLAAGDSWKELAHRA 296

Query: 299 MFHGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDKEKLEDLGAALYRLSTEE 353
            FHGG+S +T  IAGC +G++YG   V    Y+ LE + +LE+   ALY L ++E
Sbjct: 297 FFHGGDSDSTAAIAGCWWGVMYGFKGVSPSNYEKLEYRNRLEETARALYSLGSKE 351


>gi|8923417 ADP-ribosylhydrolase like 2 [Homo sapiens]
          Length = 363

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 56/237 (23%), Positives = 91/237 (38%), Gaps = 30/237 (12%)

Query: 123 FNEKGS-GFGAATKAMCIGLRYWKPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVS 181
           FN KGS G G A +   I L Y   + ++    +S +   +TH    G+ G++  AL V 
Sbjct: 143 FNGKGSYGNGGAMRVAGISLAYSSVQDVQKFARLSAQ---LTHASSLGYNGAILQALAVH 199

Query: 182 FAAQGKPLVQWGRDMLRAVPLAEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDS 241
            A QG+               +E + ++ + H  + +          +  +EER  S   
Sbjct: 200 LALQGESS-------------SEHFLKQLLGHMEDLEGDAQSVLDARELGMEERPYSSRL 246

Query: 242 ENKAIFPDNYDAEEREKTYRKWSSEGRGGRRGHDAPMIAYDALL---------AAGNSWT 292
           +      D       E      S  G G       P   Y  L          +A NS  
Sbjct: 247 KKIGELLDQASVTREEVV----SELGNGIAAFESVPTAIYCFLRCMEPDPEIPSAFNSLQ 302

Query: 293 ELCHRAMFHGGESAATGTIAGCLFGLLYGLDLVPKGLYQDLEDKEKLEDLGAALYRL 349
                ++  GG++    T+AG + G  YG+D VP+   Q  E  E+ + L  +L+R+
Sbjct: 303 RTLIYSISLGGDTDTIATMAGAIAGAYYGMDQVPESWQQSCEGYEETDILAQSLHRV 359


>gi|41352061 metalloprotease 1 [Homo sapiens]
          Length = 1037

 Score = 32.3 bits (72), Expect = 0.66
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 7/68 (10%)

Query: 89  EIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGL----RYW 144
           E +  +P   PD A+++  A+L    +L   HT   EKG  +G   K    G+     Y 
Sbjct: 868 ECIRTVPYTDPDHASLKILARLMTAKFL---HTEIREKGGAYGGGAKLSHNGIFTLYSYR 924

Query: 145 KPERLETL 152
            P  +ETL
Sbjct: 925 DPNTIETL 932


>gi|154448890 THO complex 1 [Homo sapiens]
          Length = 657

 Score = 30.0 bits (66), Expect = 3.3
 Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 4/70 (5%)

Query: 21  NVCKENSTVGMKIQEELQRSGGLDHLVLSPGEWPVSDNTIMHIATAEALTTDYWCLDDLY 80
           N  ++ ST+G K  E+ +    ++   +   E P    T   I     L   +W L D +
Sbjct: 190 NTNEQESTLGQKHTEDREEGMDVEEGEMGDEEAP----TTCSIPIDYNLYRKFWSLQDYF 245

Query: 81  REMVRCYVEI 90
           R  V+CY +I
Sbjct: 246 RNPVQCYEKI 255


>gi|4885487 myeloid leukemia factor 2 [Homo sapiens]
          Length = 248

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 32/144 (22%), Positives = 52/144 (36%), Gaps = 23/144 (15%)

Query: 160 GRMTHNHPTGFLGSLCTALFVSFA--AQGKPLVQWGRDMLRAVPLAEEYCRKTIR----- 212
           G M H    G   +  ++  +S++    G P V      +R+ P      R+T+R     
Sbjct: 88  GNMEHMTAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSG 147

Query: 213 -------HTAEYQEHWFYFEAKWQFYLEERK---ISKDSENKAIFPDNYDAE------ER 256
                  H    + H        +   +E +   I+ D    A F D +  E      +R
Sbjct: 148 LEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSRFRQQR 207

Query: 257 EKTYRKWSSEGRGGRRGHDAPMIA 280
              +R+  S G GGRR    P +A
Sbjct: 208 PLEFRRLESSGAGGRRAEGPPRLA 231


>gi|9789865 eukaryotic translation initiation factor 4E nuclear
           import factor 1 [Homo sapiens]
          Length = 985

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 12/27 (44%), Positives = 19/27 (70%)

Query: 26  NSTVGMKIQEELQRSGGLDHLVLSPGE 52
           +S++G    EEL+R  GL+  +LSPG+
Sbjct: 351 SSSLGSTPHEELERLAGLEQAILSPGQ 377


>gi|13699818 cytochrome P450, family 2, subfamily C, polypeptide 9
           [Homo sapiens]
          Length = 490

 Score = 28.5 bits (62), Expect = 9.5
 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 5/57 (8%)

Query: 76  LDDLYREMVRCYVEIVEKLPERRPDPATIEGCAQLKPNNYL--LAWHTPFNEKGSGF 130
           ++D  +E  RC VE + K      DP  I GCA   P N +  + +H  F+ K   F
Sbjct: 141 IEDRVQEEARCLVEELRKTKASPCDPTFILGCA---PCNVICSIIFHKRFDYKDQQF 194


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score = 28.5 bits (62), Expect = 9.5
 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 5/65 (7%)

Query: 238 SKDSENKAIFPDNYDAEEREKTYRKWSSEGRGGR-RGHDAPMIAYDALLAAGNSWTELCH 296
           S+ S   +  P+   AEE  +T  +  S GRGGR RG   P  A    +AAG+    LC 
Sbjct: 17  SRRSSTVSRAPERRPAEELNRTGPEGYSVGRGGRWRGTSRPPEA----VAAGHEELPLCF 72

Query: 297 RAMFH 301
               H
Sbjct: 73  ALKSH 77


>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo
           sapiens]
          Length = 1227

 Score = 28.5 bits (62), Expect = 9.5
 Identities = 17/69 (24%), Positives = 32/69 (46%), Gaps = 5/69 (7%)

Query: 202 LAEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREKTYR 261
           ++EE+  ++ +   E +EH  Y  +K     EE+   K+      +    D +ER+++  
Sbjct: 124 VSEEFWERSRQRERERREHGVYASSK-----EEKDWKKEKSRDRDYDRKRDRDERDRSRH 178

Query: 262 KWSSEGRGG 270
              SE  GG
Sbjct: 179 SSRSERDGG 187


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,386,985
Number of Sequences: 37866
Number of extensions: 660977
Number of successful extensions: 1445
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1435
Number of HSP's gapped (non-prelim): 11
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.