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Search of human proteins with 21536452
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
(247 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 517 e-147
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 492 e-139
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 457 e-129
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 451 e-127
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 218 3e-57
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 216 2e-56
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 209 1e-54
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 209 1e-54
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 209 1e-54
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 209 1e-54
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 204 7e-53
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 204 7e-53
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 204 7e-53
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 204 7e-53
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 201 5e-52
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 201 5e-52
gi|11496281 kallikrein 13 precursor [Homo sapiens] 200 1e-51
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 199 1e-51
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 199 1e-51
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 196 2e-50
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 192 3e-49
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 192 3e-49
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 190 9e-49
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 189 2e-48
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 179 2e-45
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 179 2e-45
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 179 2e-45
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 179 2e-45
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 177 8e-45
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 177 8e-45
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 517 bits (1331), Expect = e-147
Identities = 247/247 (100%), Positives = 247/247 (100%)
Query: 1 MNPFLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVS 60
MNPFLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVS
Sbjct: 1 MNPFLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVS 60
Query: 61 AAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVIN 120
AAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVIN
Sbjct: 61 AAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVIN 120
Query: 121 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 180
ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT
Sbjct: 121 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 180
Query: 181 NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIK 240
NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIK
Sbjct: 181 NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIK 240
Query: 241 DTIAANS 247
DTIAANS
Sbjct: 241 DTIAANS 247
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 492 bits (1267), Expect = e-139
Identities = 234/234 (100%), Positives = 234/234 (100%)
Query: 14 VAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRL 73
VAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRL
Sbjct: 71 VAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRL 130
Query: 74 GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPP 133
GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPP
Sbjct: 131 GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPP 190
Query: 134 AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK 193
AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK
Sbjct: 191 AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK 250
Query: 194 DSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS 247
DSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS
Sbjct: 251 DSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS 304
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 457 bits (1176), Expect = e-129
Identities = 219/247 (88%), Positives = 231/247 (93%)
Query: 1 MNPFLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVS 60
MN LIL FV AAVA PFDDDDKIVGGY CEENS+PYQVSLNSG HFCGGSLISEQWVVS
Sbjct: 1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS 60
Query: 61 AAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVIN 120
A HCYK+RIQVRLGEHNI+VLEGNEQFINAAKIIRHPKYN TLDNDI+LIKLSSPAVIN
Sbjct: 61 AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN 120
Query: 121 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 180
+RVS ISLPTAPPAAGTE LISGWGNTLS GADYPDEL+CLDAPVL+QAEC+ASYPGKIT
Sbjct: 121 SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT 180
Query: 181 NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIK 240
N+MFCVGFLEGGKDSCQ DSGGPVV NG+LQG+VSWG+GCA KNRPGVYTKVYNYVDWIK
Sbjct: 181 NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK 240
Query: 241 DTIAANS 247
DTIAANS
Sbjct: 241 DTIAANS 247
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 451 bits (1160), Expect = e-127
Identities = 214/247 (86%), Positives = 231/247 (93%)
Query: 1 MNPFLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVS 60
MNP LIL FV AA+A PFDDDDKIVGGY CEENS+PYQVSLNSG HFCGGSLI+EQWVVS
Sbjct: 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS 60
Query: 61 AAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVIN 120
A HCYK+RIQVRLGEHNI+VLEGNEQFINAAKIIRHP+Y+R TL+NDIMLIKLSS AVIN
Sbjct: 61 AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN 120
Query: 121 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 180
ARVSTISLPTAPPA GT+CLISGWGNT S GADYPDEL+CLDAPVL+QA+C+ASYPGKIT
Sbjct: 121 ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT 180
Query: 181 NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIK 240
++MFCVGFLEGGKDSCQ DSGGPVVCNGQLQGVVSWG GCA KN+PGVYTKVYNYV WIK
Sbjct: 181 SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK 240
Query: 241 DTIAANS 247
+TIAANS
Sbjct: 241 NTIAANS 247
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 218 bits (556), Expect = 3e-57
Identities = 106/241 (43%), Positives = 149/241 (61%), Gaps = 4/241 (1%)
Query: 7 LAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSH---FCGGSLISEQWVVSAAH 63
L + A+ +D++KI+GG+TC +S P+Q +L +G CGG+L+S QWV++AAH
Sbjct: 24 LQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAH 83
Query: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 123
C + +QV LG+HN++ E +Q + + + HP YN T DND+ML++L PA I V
Sbjct: 84 CGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAV 143
Query: 124 STISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM 183
I + A + GT C +SGWG S A YP L+C++ + C+ +YP IT M
Sbjct: 144 RPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGM 203
Query: 184 FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDT 242
C G +GGKDSCQ DSGGP+VC GQLQG+VSWG CA PGVYT + Y WI++T
Sbjct: 204 VCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEET 263
Query: 243 I 243
+
Sbjct: 264 M 264
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 216 bits (549), Expect = 2e-56
Identities = 111/257 (43%), Positives = 154/257 (59%), Gaps = 16/257 (6%)
Query: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAH 63
L L+ G A P +IVGG+ CE++S P+Q +L S F CGG L+ QWV++AAH
Sbjct: 8 LALSLGGTGAAPPIQS--RIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAH 65
Query: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDN-----------DIMLIK 112
C Q+ LG HN+ E QF++ ++ HP +N L+N D+ML++
Sbjct: 66 CISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLR 125
Query: 113 LSSPA-VINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAEC 171
L+ PA I V + LPT P G+ CL SGWG+ +PD+L+C+D +L EC
Sbjct: 126 LTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDEC 185
Query: 172 KASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYT 230
K ++ K+T+ M CVG LEGGKD+C DSGGP++C+G LQGV SWG+ C N+P V
Sbjct: 186 KKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAV 245
Query: 231 KVYNYVDWIKDTIAANS 247
+V +YV WI+DTIA NS
Sbjct: 246 RVLSYVKWIEDTIAENS 262
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 209 bits (533), Expect = 1e-54
Identities = 103/232 (44%), Positives = 147/232 (63%), Gaps = 6/232 (2%)
Query: 21 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 79
+ +I+ G+ C+ +S P+Q +L + CG +LI+ +W+++AAHC K R V LG+HN++
Sbjct: 19 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 78
Query: 80 VLEGNEQFINAAKIIRHPKYNRDTLD----NDIMLIKLSSPAVINARVSTISLPTAPPAA 135
EG EQ A + HP +N + NDIML+K++SP I V ++L + A
Sbjct: 79 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 138
Query: 136 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 195
GT CLISGWG+T S P L+C + ++ +C+ +YPG IT++M C EGGKDS
Sbjct: 139 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 198
Query: 196 CQRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 246
CQ DSGGP+VCN LQG++SWG CA +PGVYTKV YVDWI++T+ N
Sbjct: 199 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 250
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 209 bits (533), Expect = 1e-54
Identities = 103/232 (44%), Positives = 147/232 (63%), Gaps = 6/232 (2%)
Query: 21 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 79
+ +I+ G+ C+ +S P+Q +L + CG +LI+ +W+++AAHC K R V LG+HN++
Sbjct: 51 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 110
Query: 80 VLEGNEQFINAAKIIRHPKYNRDTLD----NDIMLIKLSSPAVINARVSTISLPTAPPAA 135
EG EQ A + HP +N + NDIML+K++SP I V ++L + A
Sbjct: 111 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 170
Query: 136 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 195
GT CLISGWG+T S P L+C + ++ +C+ +YPG IT++M C EGGKDS
Sbjct: 171 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 230
Query: 196 CQRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 246
CQ DSGGP+VCN LQG++SWG CA +PGVYTKV YVDWI++T+ N
Sbjct: 231 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 282
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 209 bits (533), Expect = 1e-54
Identities = 103/232 (44%), Positives = 147/232 (63%), Gaps = 6/232 (2%)
Query: 21 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 79
+ +I+ G+ C+ +S P+Q +L + CG +LI+ +W+++AAHC K R V LG+HN++
Sbjct: 19 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 78
Query: 80 VLEGNEQFINAAKIIRHPKYNRDTLD----NDIMLIKLSSPAVINARVSTISLPTAPPAA 135
EG EQ A + HP +N + NDIML+K++SP I V ++L + A
Sbjct: 79 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 138
Query: 136 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 195
GT CLISGWG+T S P L+C + ++ +C+ +YPG IT++M C EGGKDS
Sbjct: 139 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 198
Query: 196 CQRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 246
CQ DSGGP+VCN LQG++SWG CA +PGVYTKV YVDWI++T+ N
Sbjct: 199 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 250
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 209 bits (533), Expect = 1e-54
Identities = 108/254 (42%), Positives = 152/254 (59%), Gaps = 14/254 (5%)
Query: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAH 63
L L+F+ A+ A D DK++ G C +S P+QV+L F CG SLIS WV+SAAH
Sbjct: 5 LTLSFLLASTAA--QDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
Query: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 123
C ++VRLGEHN++ +G EQ +++I HP+Y + NDIML++L PA +N +V
Sbjct: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQV 122
Query: 124 STISLPTAPPAAGTECLISGWG----------NTLSFGADYPDELKCLDAPVLTQAECKA 173
LPT P G C++SGWG + PD L C + +++ C
Sbjct: 123 RPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDK 182
Query: 174 SYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKV 232
SYPG++TN+M C G G +SC+ DSGGP+VC G LQG+VSWG C +PGVYTKV
Sbjct: 183 SYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKV 242
Query: 233 YNYVDWIKDTIAAN 246
+Y++WI++T+ N
Sbjct: 243 CHYLEWIRETMKRN 256
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (518), Expect = 7e-53
Identities = 103/233 (44%), Positives = 146/233 (62%), Gaps = 5/233 (2%)
Query: 19 DDDDKIVGGYTCEENSLPYQVSL--NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEH 76
D +I+ G C+ ++ P+Q +L +CG L+ QW+++AAHC K +VRLG +
Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
Query: 77 NIK-VLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAA 135
++ V E +Q K I HP Y+ ND+MLIKL+ V I++ + P+A
Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
Query: 136 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 195
GT+CL+SGWG T S +P L+CL+ VL+Q C+ +YP +I ++MFC G + G+DS
Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
Query: 196 CQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAANS 247
CQ DSGGPVVCNG LQG+VSWG + CA NRPGVYT + + WI++TI ANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (518), Expect = 7e-53
Identities = 103/233 (44%), Positives = 146/233 (62%), Gaps = 5/233 (2%)
Query: 19 DDDDKIVGGYTCEENSLPYQVSL--NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEH 76
D +I+ G C+ ++ P+Q +L +CG L+ QW+++AAHC K +VRLG +
Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
Query: 77 NIK-VLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAA 135
++ V E +Q K I HP Y+ ND+MLIKL+ V I++ + P+A
Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
Query: 136 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 195
GT+CL+SGWG T S +P L+CL+ VL+Q C+ +YP +I ++MFC G + G+DS
Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
Query: 196 CQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAANS 247
CQ DSGGPVVCNG LQG+VSWG + CA NRPGVYT + + WI++TI ANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (518), Expect = 7e-53
Identities = 103/233 (44%), Positives = 146/233 (62%), Gaps = 5/233 (2%)
Query: 19 DDDDKIVGGYTCEENSLPYQVSL--NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEH 76
D +I+ G C+ ++ P+Q +L +CG L+ QW+++AAHC K +VRLG +
Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
Query: 77 NIK-VLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAA 135
++ V E +Q K I HP Y+ ND+MLIKL+ V I++ + P+A
Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
Query: 136 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 195
GT+CL+SGWG T S +P L+CL+ VL+Q C+ +YP +I ++MFC G + G+DS
Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
Query: 196 CQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAANS 247
CQ DSGGPVVCNG LQG+VSWG + CA NRPGVYT + + WI++TI ANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 204 bits (518), Expect = 7e-53
Identities = 112/250 (44%), Positives = 142/250 (56%), Gaps = 14/250 (5%)
Query: 10 VGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTR 68
VG AVP +IVGG+ CE++S P+QV++ S G CGG L+ QWV++AAHC K
Sbjct: 12 VGCTGAVPLIQS-RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKN 70
Query: 69 IQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPA 117
QV LG HN+ E Q + + HP YN L +D+ML++LS PA
Sbjct: 71 SQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPA 130
Query: 118 VINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPG 177
I V + LPT PA GT C SGWG+ P L+C+ +L+ C +Y
Sbjct: 131 KITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190
Query: 178 KITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYV 236
K+T M C G GGKD+C DSGGP+VCNG LQG+ SWG CA +P VYTKV +Y
Sbjct: 191 KVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYR 250
Query: 237 DWIKDTIAAN 246
WIKDTIAAN
Sbjct: 251 KWIKDTIAAN 260
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 201 bits (511), Expect = 5e-52
Identities = 100/243 (41%), Positives = 152/243 (62%), Gaps = 7/243 (2%)
Query: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAH 63
++L+ + AA A ++ +K+V G C++ S PYQ +L + H CGG LI WV++AAH
Sbjct: 6 VVLSLIAAAWA---EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAH 62
Query: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 123
C K +QV LG+HN++ E +++ + + + HP Y+ + D DIML++L+ PA ++ +
Sbjct: 63 CKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELI 122
Query: 124 STISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM 183
+ L A T C I GWG T D+PD ++C ++++ EC+ +YPG+IT +M
Sbjct: 123 QPLPLERDCSANTTSCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPGQITQNM 180
Query: 184 FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVDWIKDT 242
C G + GKDSCQ DSGGP+VC L+G+VSWG+ C K +PGVYT V Y +WI+ T
Sbjct: 181 LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT 240
Query: 243 IAA 245
I A
Sbjct: 241 IQA 243
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 201 bits (511), Expect = 5e-52
Identities = 100/243 (41%), Positives = 152/243 (62%), Gaps = 7/243 (2%)
Query: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAH 63
++L+ + AA A ++ +K+V G C++ S PYQ +L + H CGG LI WV++AAH
Sbjct: 6 VVLSLIAAAWA---EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAH 62
Query: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 123
C K +QV LG+HN++ E +++ + + + HP Y+ + D DIML++L+ PA ++ +
Sbjct: 63 CKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELI 122
Query: 124 STISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM 183
+ L A T C I GWG T D+PD ++C ++++ EC+ +YPG+IT +M
Sbjct: 123 QPLPLERDCSANTTSCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPGQITQNM 180
Query: 184 FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVDWIKDT 242
C G + GKDSCQ DSGGP+VC L+G+VSWG+ C K +PGVYT V Y +WI+ T
Sbjct: 181 LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT 240
Query: 243 IAA 245
I A
Sbjct: 241 IQA 243
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 200 bits (508), Expect = 1e-51
Identities = 102/225 (45%), Positives = 137/225 (60%), Gaps = 7/225 (3%)
Query: 26 GGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGN 84
GGYTC +S P+Q +L G CGG L+ +WV++AAHC K ++V LG+H + +E
Sbjct: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
Query: 85 EQFINAAKIIRHPKYNRDTL----DNDIMLIKLSSPAVINARVSTISLP-TAPPAAGTEC 139
EQ I HP+Y R D+DIML++L SP + + T+ L GT C
Sbjct: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
Query: 140 LISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRD 199
+SGWG T S +YP L+C + + + EC+ YPGKIT++M C G EGGKDSC+ D
Sbjct: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
Query: 200 SGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 243
SGGP+VCN L G+VSWG C +RPGVYT+V YV WI++TI
Sbjct: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 199 bits (507), Expect = 1e-51
Identities = 95/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 21 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 79
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++AAHC K + VRLG+H+++
Sbjct: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
Query: 80 VLEGNEQFINAAKIIRHPKYNRDTLDN---DIMLIKLSSPAVINARVSTISLPTAPPAAG 136
+G EQ I + I HP YN +++ D+ML++L A + ++V ISL G
Sbjct: 135 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 194
Query: 137 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 196
+C +SGWG S ++PD L C + + Q +C+ +YPG+IT+ M C G +G D+C
Sbjct: 195 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 253
Query: 197 QRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAA 245
Q DSGGP+VC+G LQG+ SWG C ++PGVYT + Y+DWIK I +
Sbjct: 254 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 199 bits (507), Expect = 1e-51
Identities = 95/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 21 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 79
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++AAHC K + VRLG+H+++
Sbjct: 30 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89
Query: 80 VLEGNEQFINAAKIIRHPKYNRDTLDN---DIMLIKLSSPAVINARVSTISLPTAPPAAG 136
+G EQ I + I HP YN +++ D+ML++L A + ++V ISL G
Sbjct: 90 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 149
Query: 137 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 196
+C +SGWG S ++PD L C + + Q +C+ +YPG+IT+ M C G +G D+C
Sbjct: 150 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 208
Query: 197 QRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAA 245
Q DSGGP+VC+G LQG+ SWG C ++PGVYT + Y+DWIK I +
Sbjct: 209 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 258
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 196 bits (497), Expect = 2e-50
Identities = 105/255 (41%), Positives = 143/255 (56%), Gaps = 17/255 (6%)
Query: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAH 63
L + ++GAA + +IVGG+ CE++S P+QV + S G CGG L+ QWV++AAH
Sbjct: 10 LSVTWIGAAPLIL----SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65
Query: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDN-----------DIMLIK 112
C + + + LG H++ E Q + HP Y+ L N D+ML++
Sbjct: 66 CIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLR 125
Query: 113 LSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECK 172
LS PA + V + LPT PA GT C SGWG+ P +L+C+D V++ C
Sbjct: 126 LSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA 185
Query: 173 ASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTK 231
+P K+T M C G GGK +C DSGGP+VCNG LQG+ SWG CA RP +YTK
Sbjct: 186 QVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTK 245
Query: 232 VYNYVDWIKDTIAAN 246
V +Y WIKDTI AN
Sbjct: 246 VVHYRKWIKDTIVAN 260
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 192 bits (487), Expect = 3e-49
Identities = 95/224 (42%), Positives = 133/224 (59%), Gaps = 4/224 (1%)
Query: 22 DKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKV 80
DKI+ G C S P+QV+L SG+ CGG L++E+WV++AAHC V LG +
Sbjct: 28 DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86
Query: 81 LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECL 140
+ Q I A+K RHP Y+ T ND+ML+KL+S A +++ V + LP+ GT C
Sbjct: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145
Query: 141 ISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDS 200
+SGWG T S +P +L C+D +++ +C Y + NSM C G + K++C DS
Sbjct: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205
Query: 201 GGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 243
GGP+VC G LQG+VSWG C N PGVYT+V + WI DT+
Sbjct: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 192 bits (487), Expect = 3e-49
Identities = 95/224 (42%), Positives = 133/224 (59%), Gaps = 4/224 (1%)
Query: 22 DKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKV 80
DKI+ G C S P+QV+L SG+ CGG L++E+WV++AAHC V LG +
Sbjct: 28 DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86
Query: 81 LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECL 140
+ Q I A+K RHP Y+ T ND+ML+KL+S A +++ V + LP+ GT C
Sbjct: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145
Query: 141 ISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDS 200
+SGWG T S +P +L C+D +++ +C Y + NSM C G + K++C DS
Sbjct: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205
Query: 201 GGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 243
GGP+VC G LQG+VSWG C N PGVYT+V + WI DT+
Sbjct: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 190 bits (483), Expect = 9e-49
Identities = 102/242 (42%), Positives = 143/242 (59%), Gaps = 10/242 (4%)
Query: 4 FLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAA 62
FL+L +G + A KI G C NS P+QV L G+ CGG LI +WV++AA
Sbjct: 6 FLLLCVLGLSQAAT----PKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAA 61
Query: 63 HCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKY--NRDTLDNDIMLIKLSSPAVIN 120
HC +R VRLGEH++ L+ EQ ++ + HP Y + ++D+ L++L P +
Sbjct: 62 HCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVT 121
Query: 121 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 180
+ V + LP AGTEC +SGWG T +PD L+CL+ +++ A C YPG+IT
Sbjct: 122 SSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRIT 181
Query: 181 NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH--GCAWKNRPGVYTKVYNYVDW 238
++M C G + G+D+CQ DSGGP+VC G LQG+VSWG C PGVYT + YVDW
Sbjct: 182 SNMVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDW 240
Query: 239 IK 240
I+
Sbjct: 241 IR 242
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 189 bits (480), Expect = 2e-48
Identities = 99/227 (43%), Positives = 135/227 (59%), Gaps = 6/227 (2%)
Query: 21 DDKIVGGYTCEENSLPYQVSLNSGSH-FCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 79
D + +G C NS P+Q L + FCG +LIS++W+++AAHC K + VRLGEH++
Sbjct: 20 DTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLW 79
Query: 80 VLEGNEQFINAAKIIRHPKYNRDTLDND----IMLIKLSSPAVINARVSTISLPTAPPAA 135
EG EQ HP +N+D ND IMLI+L A ++ V ++L +
Sbjct: 80 KWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCVSP 139
Query: 136 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 195
G +CLISGWG S A +P L+C + +L C +YPG I++SM C G EGG+ S
Sbjct: 140 GMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEGGRGS 199
Query: 196 CQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKD 241
CQ DSGGP+VCNG L GVVS G C+ RP VYT V +Y+DWI++
Sbjct: 200 CQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQE 246
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 179 bits (455), Expect = 2e-45
Identities = 98/236 (41%), Positives = 138/236 (58%), Gaps = 10/236 (4%)
Query: 4 FLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAA 62
FL+L +G + A KI G C NS P+QV L G+ CGG LI +WV++AA
Sbjct: 6 FLLLCVLGLSQAAT----PKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAA 61
Query: 63 HCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKY--NRDTLDNDIMLIKLSSPAVIN 120
HC +R VRLGEH++ L+ EQ ++ + HP Y + ++D+ L++L P +
Sbjct: 62 HCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVT 121
Query: 121 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 180
+ V + LP AGTEC +SGWG T +PD L+CL+ +++ A C YPG+IT
Sbjct: 122 SSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRIT 181
Query: 181 NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH--GCAWKNRPGVYTKVYN 234
++M C G + G+D+CQ DSGGP+VC G LQG+VSWG C PGVYT + N
Sbjct: 182 SNMVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICN 236
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 179 bits (454), Expect = 2e-45
Identities = 96/256 (37%), Positives = 144/256 (56%), Gaps = 16/256 (6%)
Query: 5 LILAFVGAAVAVPFDDDDKIVG----GYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVV 59
L++A + AA A +D + G C S P+QVSL +G F C G L+ + WV+
Sbjct: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
Query: 60 SAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYN--------RDTLDNDIMLI 111
+AAHC + R+G+ ++ +L+G EQ + + HPKY+ R T ++D+ML+
Sbjct: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
Query: 112 KLSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAEC 171
KL+ P V+ RV + LP G +C ++GWG T + Y L C +L+ EC
Sbjct: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
Query: 172 KASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYT 230
+ YPG +TN+M C G L+ G+D CQ DSGGP+VC+ LQG++SWG + C P VYT
Sbjct: 202 EVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYT 260
Query: 231 KVYNYVDWIKDTIAAN 246
++ Y+ WI I +N
Sbjct: 261 QICKYMSWINKVIRSN 276
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 179 bits (454), Expect = 2e-45
Identities = 96/256 (37%), Positives = 144/256 (56%), Gaps = 16/256 (6%)
Query: 5 LILAFVGAAVAVPFDDDDKIVG----GYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVV 59
L++A + AA A +D + G C S P+QVSL +G F C G L+ + WV+
Sbjct: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
Query: 60 SAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYN--------RDTLDNDIMLI 111
+AAHC + R+G+ ++ +L+G EQ + + HPKY+ R T ++D+ML+
Sbjct: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
Query: 112 KLSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAEC 171
KL+ P V+ RV + LP G +C ++GWG T + Y L C +L+ EC
Sbjct: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
Query: 172 KASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYT 230
+ YPG +TN+M C G L+ G+D CQ DSGGP+VC+ LQG++SWG + C P VYT
Sbjct: 202 EVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYT 260
Query: 231 KVYNYVDWIKDTIAAN 246
++ Y+ WI I +N
Sbjct: 261 QICKYMSWINKVIRSN 276
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 179 bits (454), Expect = 2e-45
Identities = 96/256 (37%), Positives = 144/256 (56%), Gaps = 16/256 (6%)
Query: 5 LILAFVGAAVAVPFDDDDKIVG----GYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVV 59
L++A + AA A +D + G C S P+QVSL +G F C G L+ + WV+
Sbjct: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
Query: 60 SAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYN--------RDTLDNDIMLI 111
+AAHC + R+G+ ++ +L+G EQ + + HPKY+ R T ++D+ML+
Sbjct: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
Query: 112 KLSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAEC 171
KL+ P V+ RV + LP G +C ++GWG T + Y L C +L+ EC
Sbjct: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
Query: 172 KASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYT 230
+ YPG +TN+M C G L+ G+D CQ DSGGP+VC+ LQG++SWG + C P VYT
Sbjct: 202 EVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYT 260
Query: 231 KVYNYVDWIKDTIAAN 246
++ Y+ WI I +N
Sbjct: 261 QICKYMSWINKVIRSN 276
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 177 bits (449), Expect = 8e-45
Identities = 95/246 (38%), Positives = 139/246 (56%), Gaps = 8/246 (3%)
Query: 4 FLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSH-FCGGSLISEQWVVSAA 62
+LIL G+ V+ +I+ G C +S P+Q +L + FC G L+ QWV+SAA
Sbjct: 14 YLILGVAGSLVS---GSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAA 70
Query: 63 HCYKTRIQVRLGEHNIKV-LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINA 121
HC++ + LG H+++ E Q + A+ +RHP+YNR L ND+MLIKL +
Sbjct: 71 HCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD 130
Query: 122 RVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITN 181
+ +IS+ + P AG CL+SGWG L P L+C++ V+++ C Y
Sbjct: 131 TIRSISIASQCPTAGNSCLVSGWG--LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHP 188
Query: 182 SMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIK 240
SMFC G KDSC DSGGP++CNG LQG+VS+G C PGVYT + + +WI+
Sbjct: 189 SMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248
Query: 241 DTIAAN 246
T+ A+
Sbjct: 249 KTVQAS 254
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 177 bits (449), Expect = 8e-45
Identities = 88/235 (37%), Positives = 134/235 (57%), Gaps = 12/235 (5%)
Query: 23 KIVGGYTCEENSLPYQVSLNSGS-HFCGGSLISEQWVVSAAHCYK----TRIQVRLGEHN 77
++VGG+ +P+QVSL GS HFCG +++ ++W++SAAHC+ +++ LG +
Sbjct: 503 RVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTAS 562
Query: 78 IKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPA--A 135
+ L G+ I +++ HP YN LD D+ +++L+SP N + + LP A
Sbjct: 563 LLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPV 622
Query: 136 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 195
G +C+ISGWGNT A P+ L+ ++ Q C Y +T+ M C GFLEG DS
Sbjct: 623 GRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDS 682
Query: 196 CQRDSGGPVVCNG-----QLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAA 245
CQ DSGGP+ C L G+VSWG GCA +PGVYT++ WI + +++
Sbjct: 683 CQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSS 737
Score = 162 bits (409), Expect = 3e-40
Identities = 89/232 (38%), Positives = 124/232 (53%), Gaps = 17/232 (7%)
Query: 23 KIVGGYTCEENSLPYQVSLNSGS-HFCGGSLISEQWVVSAAHCYK-----TRIQVRLGEH 76
+IVGG P+Q SL HFCG ++I+ +W+VSAAHC+ T+ +G
Sbjct: 202 RIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGAT 261
Query: 77 NIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTA----P 132
+ E + +I++HP YN DT D D+ +++L+SP + + LP A P
Sbjct: 262 YLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFP 321
Query: 133 PAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGG 192
P+ +CLISGWG P+ L+ +L QA C + Y +T+ M C G+L+G
Sbjct: 322 PSK--KCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLDGK 379
Query: 193 KDSCQRDSGGPVVCNGQ-----LQGVVSWGHGCAWKNRPGVYTKVYNYVDWI 239
DSCQ DSGGP+VC L G+VSWG GCA RPGVY +V DWI
Sbjct: 380 VDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWI 431
Score = 148 bits (374), Expect = 4e-36
Identities = 89/231 (38%), Positives = 124/231 (53%), Gaps = 17/231 (7%)
Query: 23 KIVGGYTCEENSLPYQVSL--NSGSHFCGGSLISEQWVVSAAHCYKTRIQVR-----LGE 75
+IVGG P+QVSL H CG L++E+W++SAAHC+ + LG
Sbjct: 826 RIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGT 885
Query: 76 HNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPT-AP-P 133
+ EG Q A+I +HP YN TLD D+ L++L+ P + V I LP AP P
Sbjct: 886 PFLSGAEG--QLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRP 943
Query: 134 AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK 193
GT C+I+GWG+ G +L+ +L++ C+ YP +I++ M C GF +GG
Sbjct: 944 PDGTRCVITGWGSVRE-GGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGV 1002
Query: 194 DSCQRDSGGPVVCNGQ-----LQGVVSWGHGCAWKNRPGVYTKVYNYVDWI 239
DSC D+GGP+ C L GV SWG+GC + PGVYT+V WI
Sbjct: 1003 DSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWI 1053
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,281,423
Number of Sequences: 37866
Number of extensions: 460427
Number of successful extensions: 1622
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 896
Number of HSP's gapped (non-prelim): 195
length of query: 247
length of database: 18,247,518
effective HSP length: 100
effective length of query: 147
effective length of database: 14,460,918
effective search space: 2125754946
effective search space used: 2125754946
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.