Guide to the Human Genome
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Search of human proteins with 214830753

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|214830753 meckelin isoform 2 [Homo sapiens]
         (914 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|214830753 meckelin isoform 2 [Homo sapiens]                       1843   0.0  
gi|187281580 meckelin isoform 1 [Homo sapiens]                       1731   0.0  
gi|239755282 PREDICTED: similar to Tripartite motif-containing p...    35   0.42 
gi|239752570 PREDICTED: hypothetical protein XP_002348292 [Homo ...    35   0.42 
gi|34147532 myosin, light chain 10, regulatory [Homo sapiens]          31   4.6  
gi|194578909 eukaryotic translation initiation factor 4E isoform...    30   7.9  
gi|30794260 hypothetical protein LOC90529 [Homo sapiens]               30   7.9  

>gi|214830753 meckelin isoform 2 [Homo sapiens]
          Length = 914

 Score = 1843 bits (4775), Expect = 0.0
 Identities = 914/914 (100%), Positives = 914/914 (100%)

Query: 1   MSLSHWPYFRLVLNFRPQVICLPQPPKVLGYRLEPPHLTLACTLEGMYNIIEEILERDIN 60
           MSLSHWPYFRLVLNFRPQVICLPQPPKVLGYRLEPPHLTLACTLEGMYNIIEEILERDIN
Sbjct: 1   MSLSHWPYFRLVLNFRPQVICLPQPPKVLGYRLEPPHLTLACTLEGMYNIIEEILERDIN 60

Query: 61  GTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSST 120
           GTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSST
Sbjct: 61  GTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSST 120

Query: 121 GNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSYD 180
           GNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSYD
Sbjct: 121 GNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSYD 180

Query: 181 FATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFSF 240
           FATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFSF
Sbjct: 181 FATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFSF 240

Query: 241 KGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEIP 300
           KGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEIP
Sbjct: 241 KGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEIP 300

Query: 301 ISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTRR 360
           ISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTRR
Sbjct: 301 ISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTRR 360

Query: 361 IFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDAN 420
           IFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDAN
Sbjct: 361 IFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDAN 420

Query: 421 SQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTVV 480
           SQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTVV
Sbjct: 421 SQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTVV 480

Query: 481 KFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALKA 540
           KFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALKA
Sbjct: 481 KFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALKA 540

Query: 541 LQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQ 600
           LQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQ
Sbjct: 541 LQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQ 600

Query: 601 TVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALWL 660
           TVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALWL
Sbjct: 601 TVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALWL 660

Query: 661 AIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADTN 720
           AIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADTN
Sbjct: 661 AIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADTN 720

Query: 721 MEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLLS 780
           MEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLLS
Sbjct: 721 MEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLLS 780

Query: 781 SSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFYN 840
           SSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFYN
Sbjct: 781 SSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFYN 840

Query: 841 DEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQK 900
           DEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQK
Sbjct: 841 DEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQK 900

Query: 901 NLASKTLVDQRFLI 914
           NLASKTLVDQRFLI
Sbjct: 901 NLASKTLVDQRFLI 914


>gi|187281580 meckelin isoform 1 [Homo sapiens]
          Length = 995

 Score = 1731 bits (4483), Expect = 0.0
 Identities = 873/915 (95%), Positives = 883/915 (96%), Gaps = 8/915 (0%)

Query: 7   PYFRLVLNFR-PQVICLPQPPKVLGYRLEPPHLTLAC----TLEGMYN--IIEEILERDI 59
           P F+++ N   P +IC   P  + G   E     ++C    T EG  +  I   ++ERDI
Sbjct: 82  PGFQMISNNGGPAIICKKCPENMKGVT-EDGWNCISCPSDLTAEGKCHCPIGHILVERDI 140

Query: 60  NGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSS 119
           NGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSS
Sbjct: 141 NGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSS 200

Query: 120 TGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSY 179
           TGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSY
Sbjct: 201 TGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSY 260

Query: 180 DFATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFS 239
           DFATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFS
Sbjct: 261 DFATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFS 320

Query: 240 FKGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEI 299
           FKGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEI
Sbjct: 321 FKGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEI 380

Query: 300 PISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTR 359
           PISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTR
Sbjct: 381 PISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTR 440

Query: 360 RIFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDA 419
           RIFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDA
Sbjct: 441 RIFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDA 500

Query: 420 NSQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTV 479
           NSQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTV
Sbjct: 501 NSQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTV 560

Query: 480 VKFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALK 539
           VKFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALK
Sbjct: 561 VKFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALK 620

Query: 540 ALQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEI 599
           ALQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEI
Sbjct: 621 ALQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEI 680

Query: 600 QTVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALW 659
           QTVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALW
Sbjct: 681 QTVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALW 740

Query: 660 LAIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADT 719
           LAIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADT
Sbjct: 741 LAIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADT 800

Query: 720 NMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLL 779
           NMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLL
Sbjct: 801 NMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLL 860

Query: 780 SSSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFY 839
           SSSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFY
Sbjct: 861 SSSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFY 920

Query: 840 NDEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQ 899
           NDEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQ
Sbjct: 921 NDEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQ 980

Query: 900 KNLASKTLVDQRFLI 914
           KNLASKTLVDQRFLI
Sbjct: 981 KNLASKTLVDQRFLI 995


>gi|239755282 PREDICTED: similar to Tripartite motif-containing
          protein 43-like protein 1 [Homo sapiens]
          Length = 185

 Score = 34.7 bits (78), Expect = 0.42
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 1/63 (1%)

Query: 10 RLVLNFRPQVICLPQPPKVLGYRLEPPHLTLACTLEGMYNIIEEILERDINGTLLSQATC 69
          RLVL+   Q I LPQPPK L Y+ EP    L+    G  N+ ++ ++ D       +  C
Sbjct: 17 RLVLDSLDQAILLPQPPKELDYKHEPLCPALSFFHTGGKNLGKK-MDLDFPQAFQKELNC 75

Query: 70 ELC 72
           +C
Sbjct: 76 LIC 78


>gi|239752570 PREDICTED: hypothetical protein XP_002348292 [Homo
          sapiens]
          Length = 185

 Score = 34.7 bits (78), Expect = 0.42
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 1/63 (1%)

Query: 10 RLVLNFRPQVICLPQPPKVLGYRLEPPHLTLACTLEGMYNIIEEILERDINGTLLSQATC 69
          RLVL+   Q I LPQPPK L Y+ EP    L+    G  N+ ++ ++ D       +  C
Sbjct: 17 RLVLDSLDQAILLPQPPKELDYKHEPLCPALSFFHTGGKNLGKK-MDLDFPQAFQKELNC 75

Query: 70 ELC 72
           +C
Sbjct: 76 LIC 78


>gi|34147532 myosin, light chain 10, regulatory [Homo sapiens]
          Length = 226

 Score = 31.2 bits (69), Expect = 4.6
 Identities = 15/21 (71%), Positives = 16/21 (76%)

Query: 10 RLVLNFRPQVICLPQPPKVLG 30
          RLV N  PQVI  P+PPKVLG
Sbjct: 4  RLVSNSWPQVILPPRPPKVLG 24


>gi|194578909 eukaryotic translation initiation factor 4E isoform 2
           [Homo sapiens]
          Length = 248

 Score = 30.4 bits (67), Expect = 7.9
 Identities = 16/24 (66%), Positives = 17/24 (70%)

Query: 10  RLVLNFRPQVICLPQPPKVLGYRL 33
           RLV NF PQVI   QPPKVL  +L
Sbjct: 142 RLVSNFWPQVILPLQPPKVLELQL 165


>gi|30794260 hypothetical protein LOC90529 [Homo sapiens]
          Length = 287

 Score = 30.4 bits (67), Expect = 7.9
 Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 2/72 (2%)

Query: 720 NMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLL 779
           N    +++  ++  N+C++ G +  T   +F  A       HYD I+E+L+ K  P  L+
Sbjct: 104 NYYNASVSCCKQRNNVCTRAGFMSKTQRGSFAFADKGPPPGHYD-INESLV-KQSPNTLM 161

Query: 780 SSSASTFEQSIK 791
           S   S   + +K
Sbjct: 162 SCFKSKTNRGLK 173


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,371,376
Number of Sequences: 37866
Number of extensions: 1367635
Number of successful extensions: 3803
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3797
Number of HSP's gapped (non-prelim): 7
length of query: 914
length of database: 18,247,518
effective HSP length: 111
effective length of query: 803
effective length of database: 14,044,392
effective search space: 11277646776
effective search space used: 11277646776
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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