Search of human proteins with 21361315

Search of human proteins with 21361315

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361315 transmembrane 9 superfamily member 1 isoform a
[Homo sapiens]
         (606 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361315 transmembrane 9 superfamily member 1 isoform a [Homo...  1248   0.0  
gi|62460635 transmembrane 9 superfamily member 1 isoform b [Homo...   986   0.0  
gi|190194386 transmembrane 9 superfamily member 3 [Homo sapiens]      355   5e-98
gi|164519076 transmembrane 9 superfamily protein member 4 [Homo ...   334   1e-91
gi|4758874 transmembrane 9 superfamily member 2 [Homo sapiens]        305   8e-83
gi|196123588 NADH dehydrogenase subunit 4 [Homo sapiens neandert...    37   0.053
gi|251831116 NADH dehydrogenase subunit 4 [Homo sapiens]               37   0.053
gi|10863913 solute carrier family 8 (sodium/calcium exchanger), ...    31   2.9  
gi|163914373 solute carrier family 8 (sodium/calcium exchanger),...    31   2.9  
gi|163914371 solute carrier family 8 (sodium/calcium exchanger),...    31   2.9  
gi|163914369 solute carrier family 8 (sodium/calcium exchanger),...    31   2.9  
gi|30581137 phosphatidylinositol glycan anchor biosynthesis, cla...    31   3.8  
gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]           30   6.4  
gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2 is...    30   6.4  
gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2 is...    30   6.4  
gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2 is...    30   6.4  
gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2 is...    30   6.4  
gi|56682974 zinc finger, DHHC domain containing 9 [Homo sapiens]       30   8.4  
gi|56682972 zinc finger, DHHC domain containing 9 [Homo sapiens]       30   8.4  
gi|31542246 kelch-like 36 [Homo sapiens]                               30   8.4  

>gi|21361315 transmembrane 9 superfamily member 1 isoform a [Homo
           sapiens]
          Length = 606

 Score = 1248 bits (3228), Expect = 0.0
 Identities = 606/606 (100%), Positives = 606/606 (100%)

Query: 1   MTVVGNPRSWSCQWLPILILLLGTGHGPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYH 60
           MTVVGNPRSWSCQWLPILILLLGTGHGPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYH
Sbjct: 1   MTVVGNPRSWSCQWLPILILLLGTGHGPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYH 60

Query: 61  YYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLR 120
           YYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLR
Sbjct: 61  YYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLR 120

Query: 121 QAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVS 180
           QAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVS
Sbjct: 121 QAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVS 180

Query: 181 VRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSII 240
           VRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSII
Sbjct: 181 VRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSII 240

Query: 241 NSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTDVFRF 300
           NSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTDVFRF
Sbjct: 241 NSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTDVFRF 300

Query: 301 PPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVS 360
           PPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVS
Sbjct: 301 PPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVS 360

Query: 361 SHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWL 420
           SHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWL
Sbjct: 361 SHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWL 420

Query: 421 LVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISV 480
           LVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISV
Sbjct: 421 LVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISV 480

Query: 481 ELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVG 540
           ELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVG
Sbjct: 481 ELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVG 540

Query: 541 STGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIY 600
           STGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIY
Sbjct: 541 STGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIY 600

Query: 601 VNLKMD 606
           VNLKMD
Sbjct: 601 VNLKMD 606


>gi|62460635 transmembrane 9 superfamily member 1 isoform b [Homo
           sapiens]
          Length = 489

 Score =  986 bits (2549), Expect = 0.0
 Identities = 475/475 (100%), Positives = 475/475 (100%)

Query: 1   MTVVGNPRSWSCQWLPILILLLGTGHGPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYH 60
           MTVVGNPRSWSCQWLPILILLLGTGHGPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYH
Sbjct: 1   MTVVGNPRSWSCQWLPILILLLGTGHGPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYH 60

Query: 61  YYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLR 120
           YYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLR
Sbjct: 61  YYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLR 120

Query: 121 QAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVS 180
           QAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVS
Sbjct: 121 QAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVS 180

Query: 181 VRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSII 240
           VRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSII
Sbjct: 181 VRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSII 240

Query: 241 NSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTDVFRF 300
           NSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTDVFRF
Sbjct: 241 NSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTDVFRF 300

Query: 301 PPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVS 360
           PPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVS
Sbjct: 301 PPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVS 360

Query: 361 SHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWL 420
           SHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWL
Sbjct: 361 SHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWL 420

Query: 421 LVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPF 475
           LVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPF
Sbjct: 421 LVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPF 475


>gi|190194386 transmembrane 9 superfamily member 3 [Homo sapiens]
          Length = 589

 Score =  355 bits (912), Expect = 5e-98
 Identities = 205/600 (34%), Positives = 320/600 (53%), Gaps = 34/600 (5%)

Query: 14  WLPILILLLGTGHGPGVEGVTH---YKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPE 70
           WL +L+L       P      H   Y+  + V+L++N VGPYHN QETY Y+ LP C   
Sbjct: 17  WLLLLLL-------PRTRADEHEHTYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGS 69

Query: 71  K--IRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLRQAIEELYY 128
           K  I H   +LGE L G  +  S  +I+F+++V     C + L   + +    AI+  Y+
Sbjct: 70  KKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPATYCEIDLDKEKRDAFVYAIKNHYW 129

Query: 129 FEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANV-SVRDVKPH 187
           ++  +DDLPI G VG  +E+G         LWT+    + F+G+RI+  N+ S   VK  
Sbjct: 130 YQMYIDDLPIWGIVGEADENG-----EDYYLWTYKKLEIGFNGNRIVDVNLTSEGKVK-- 182

Query: 188 SLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVF 247
               L P+  + ++  YSV+W ++ V+      +  D  FF     IHW SI NS ++V 
Sbjct: 183 ----LVPNTKIQMS--YSVKWKKSDVKFEDRFDKYLDPSFFQH--RIHWFSIFNSFMMVI 234

Query: 248 LLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDN-GWKIIHTDVFRFPPYRGL 306
            LVG V++ILMR LR D ARY+ +EE        D D GD  GWK +H DVFR   +  +
Sbjct: 235 FLVGLVSMILMRTLRKDYARYSKEEEMDDM----DRDLGDEYGWKQVHGDVFRPSSHPLI 290

Query: 307 LCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQ 366
             +++G G Q  A+   +I++A++      R G++ S AI +YA T  ++GY     Y +
Sbjct: 291 FSSLIGSGCQIFAVSLIVIIVAMIEDLYTER-GSMLSTAIFVYAATSPVNGYFGGSLYAR 349

Query: 367 IGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPL 426
            GG RW+  + +   L       T   +N +     +++A+P  T++ +  +   V  PL
Sbjct: 350 QGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPL 409

Query: 427 TVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELYYIF 486
            ++G I G+N +   + PCR   + R IP + W+    + + +GG LPF +I +E+Y+IF
Sbjct: 410 NLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIF 469

Query: 487 ATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFI 546
            + W  + Y +YG +  V  IL  V  C++I  TYF L+ EDYRW W S LS  ST +++
Sbjct: 470 TSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYV 529

Query: 547 FLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD 606
           ++YS +YY  ++ M G  QT  +FGY  +      +M G I +  +  F+R IY N+K+D
Sbjct: 530 YMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID 589


>gi|164519076 transmembrane 9 superfamily protein member 4 [Homo
           sapiens]
          Length = 642

 Score =  334 bits (857), Expect = 1e-91
 Identities = 201/653 (30%), Positives = 325/653 (49%), Gaps = 77/653 (11%)

Query: 14  WLPILILLLG------TGHGPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYHYYQLPVC 67
           WLP  +LL          + PGV  +  ++  DPV +   K+      Q  Y YY LP C
Sbjct: 7   WLPWSLLLFSLMCETSAFYVPGVAPINFHQ-NDPVEIKAVKLTSSRT-QLPYEYYSLPFC 64

Query: 68  CPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQ-----LSSAQVEQLRQA 122
            P KI +K+ +LGEVL GDR+  + +++      +  +LC        L+  Q   + + 
Sbjct: 65  QPSKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCSQSNKPVTLTVEQSRLVAER 124

Query: 123 IEELYYFEFVVDDLPIRGFVGYM----------EESGFLPHSHKIG--------LWTHLD 164
           I E YY   + D+LP+   +             E+     H +++G        L  HL 
Sbjct: 125 ITEDYYVHLIADNLPVATRLELYSNRDSDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLS 184

Query: 165 FHLEFHGD---------------RIIFANVSVRDVK----------------PHSLDGLR 193
           F L +H +                +I  ++ + D+K                P  +D  +
Sbjct: 185 FILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKADEKSSCTLPEGTNSSPQEIDPTK 244

Query: 194 PDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFV 253
            ++   L  TYSV W E+ ++  S      D       ++IHW SIINS+V+VF L G +
Sbjct: 245 ENQ---LYFTYSVHWEESDIKWASRW----DTYLTMSDVQIHWFSIINSVVVVFFLSGIL 297

Query: 254 AVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTDVFRFPPYRGLLCAVLGV 313
           ++I++R LR D+A YN +++             ++GWK++H DVFR P Y  +L ++LG 
Sbjct: 298 SMIIIRTLRKDIANYNKEDDIEDT-------MEESGWKLVHGDVFRPPQYPMILSSLLGS 350

Query: 314 GAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWV 373
           G Q   +   +I +A+LGM +    GA+ + A  L+       G+ +   YR + G RW 
Sbjct: 351 GIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWK 410

Query: 374 WNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIF 433
                T +L+    F    V+N   W   S+ A+P  T++ LL +W  +  PL  +G  F
Sbjct: 411 KGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYF 470

Query: 434 GKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELYYIFATVWGRE 493
           G     P+D P RT  I R+IP Q WY +  + + + G LPF A+ +EL++IF+ +W  +
Sbjct: 471 GFRK-QPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQ 529

Query: 494 QYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFY 553
            Y L+G LF VF IL+   + ISI + YFQL  EDYRWWWR+ L  G +  ++ +Y++FY
Sbjct: 530 FYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFY 589

Query: 554 YARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD 606
           +  + ++   + ++ +FGY+ L    F+L+ GTI F+++  F+R IY  +K+D
Sbjct: 590 FVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID 642


>gi|4758874 transmembrane 9 superfamily member 2 [Homo sapiens]
          Length = 663

 Score =  305 bits (781), Expect = 8e-83
 Identities = 205/672 (30%), Positives = 333/672 (49%), Gaps = 88/672 (13%)

Query: 6   NPRSWSCQWLPILILLLGTGHGPGVEGVTHYKAGDPVI----------------LYVNKV 49
           +P  W  + L + +LLLG   GP   G  +     PV                 L+VN++
Sbjct: 9   SPPRWP-RLLLLSLLLLGAVPGPRRSGAFYLPGLAPVNFCDEEKKSDECKAEIELFVNRL 67

Query: 50  GPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHM 109
               +    Y Y     C   + +  S +LG+VL G+R+  S Y+  F +    +++C  
Sbjct: 68  DSVESVLP-YEYTAFDFCQASEGKRPSENLGQVLFGERIEPSPYKFTFNKKETCKLVCTK 126

Query: 110 QLSSAQVEQLRQAIEEL-------YYFEFVVDDLPIR--------------GF-VG-YME 146
              + + E  +Q +E L       Y   ++VD++P+               GF +G Y+ 
Sbjct: 127 TYHTEKAED-KQKLEFLKKSMLLNYQHHWIVDNMPVTWCYDVEDGQRFCNPGFPIGCYIT 185

Query: 147 ESGFLPHSHKIG----------LWTHLDFHLEFH-------GDRIIFANVSVRDVKPHSL 189
           + G    +  I           ++ H+D  + +H       G R++ A +  +  K   +
Sbjct: 186 DKGHAKDACVISSDFHERDTFYIFNHVDIKIYYHVVETGSMGARLVAAKLEPKSFKHTHI 245

Query: 190 DGLRPD-------------EFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHW 236
           D  +PD               + + +TYSV + E    R + R         P T  I W
Sbjct: 246 D--KPDCSGPPMDISNKASGEIKIAYTYSVSFEEDDKIRWASRWDYILESM-PHT-HIQW 301

Query: 237 LSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTD 296
            SI+NS+V+V  L G VA+I++R L  D+ARYN  + T  A       Q + GWK++H D
Sbjct: 302 FSIMNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSTEDA-------QEEFGWKLVHGD 354

Query: 297 VFRFPPYRGLLCAV-LGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCI 355
           +FR PP +G+L +V LG G Q L +    +  A LG  +    GA+ + A++L+ L    
Sbjct: 355 IFR-PPRKGMLLSVFLGSGTQILIMTFVTLFFACLGFLSPANRGALMTCAVVLWVLLGTP 413

Query: 356 SGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLL 415
           +GYV++ FY+  GGE+W  N++LT+ L     F  + ++N + W  GS+ A+P  T++ +
Sbjct: 414 AGYVAARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTLVAI 473

Query: 416 LTVWLLVGFPLTVIGGIFG-KNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLP 474
           L +W  +  PLT IG  FG K NA   + P RT  I R+IP Q +Y   +  + +GG LP
Sbjct: 474 LALWFCISVPLTFIGAYFGFKKNA--IEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILP 531

Query: 475 FSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWR 534
           F  I ++L++I  ++W  + Y ++G LF VF IL+   +  +I L YF L  EDY W WR
Sbjct: 532 FGCIFIQLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEATILLCYFHLCAEDYHWQWR 591

Query: 535 SVLSVGSTGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLK 594
           S L+ G T ++  +Y+V Y+  +  ++G   T+ +FGY+++   +FFL  GTI FF+   
Sbjct: 592 SFLTSGFTAVYFLIYAVHYFFSKLQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACFW 651

Query: 595 FIRYIYVNLKMD 606
           F+  IY  +K+D
Sbjct: 652 FVTKIYSVVKVD 663


>gi|196123588 NADH dehydrogenase subunit 4 [Homo sapiens
           neanderthalensis]
          Length = 459

 Score = 37.0 bits (84), Expect = 0.053
 Identities = 39/163 (23%), Positives = 69/163 (42%), Gaps = 33/163 (20%)

Query: 373 VWNIILTTSLFS--VPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIG 430
           +W    T SL    +P      + N++   + +  + P TT LL+LT WLL   PLT++ 
Sbjct: 23  IWINTTTHSLIISIIPLLFFNQINNNLFSCSPTFSSDPLTTPLLMLTTWLL---PLTIMA 79

Query: 431 GIFGKNNASPFDAPCRTKNIARE-IPPQPWYKSTVIHMTVGGFLPFSAISVELYYIF--- 486
                            ++++ E +  +  Y S +I + +   + F+A  + ++YIF   
Sbjct: 80  S---------------QRHLSSEPLSRKKLYLSMLISLQISLIMTFTATELIMFYIFFET 124

Query: 487 --------ATVWGREQYTLYGILFFVFAILLSVGACISIALTY 521
                    T WG +   L    +F+F  L+     + IAL Y
Sbjct: 125 TLIPTLAIITRWGNQPERLNAGTYFLFYTLVG-SLPLLIALIY 166


>gi|251831116 NADH dehydrogenase subunit 4 [Homo sapiens]
          Length = 459

 Score = 37.0 bits (84), Expect = 0.053
 Identities = 39/163 (23%), Positives = 69/163 (42%), Gaps = 33/163 (20%)

Query: 373 VWNIILTTSLFS--VPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIG 430
           +W    T SL    +P      + N++   + +  + P TT LL+LT WLL   PLT++ 
Sbjct: 23  IWINTTTHSLIISIIPLLFFNQINNNLFSCSPTFSSDPLTTPLLMLTTWLL---PLTIMA 79

Query: 431 GIFGKNNASPFDAPCRTKNIARE-IPPQPWYKSTVIHMTVGGFLPFSAISVELYYIF--- 486
                            ++++ E +  +  Y S +I + +   + F+A  + ++YIF   
Sbjct: 80  S---------------QRHLSSEPLSRKKLYLSMLISLQISLIMTFTATELIMFYIFFET 124

Query: 487 --------ATVWGREQYTLYGILFFVFAILLSVGACISIALTY 521
                    T WG +   L    +F+F  L+     + IAL Y
Sbjct: 125 TLIPTLAIITRWGNQPERLNAGTYFLFYTLVG-SLPLLIALIY 166


>gi|10863913 solute carrier family 8 (sodium/calcium exchanger),
           member 1 isoform A [Homo sapiens]
          Length = 973

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 16/96 (16%)

Query: 507 ILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVF--------YYARRS 558
           + L +G   SIA  Y   +GE ++      +S G+    + L+++F         Y RR 
Sbjct: 878 VFLGIGVAWSIAAIYHAANGEQFK------VSPGTLAFSVTLFTIFAFINVGVLLYRRRP 931

Query: 559 NMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLK 594
            + G +         LLT  +F L+     FFSSL+
Sbjct: 932 EIGGELGGPR--TAKLLTSCLFVLLWLLYIFFSSLE 965


>gi|163914373 solute carrier family 8 (sodium/calcium exchanger),
           member 1 isoform D [Homo sapiens]
          Length = 937

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 16/96 (16%)

Query: 507 ILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVF--------YYARRS 558
           + L +G   SIA  Y   +GE ++      +S G+    + L+++F         Y RR 
Sbjct: 842 VFLGIGVAWSIAAIYHAANGEQFK------VSPGTLAFSVTLFTIFAFINVGVLLYRRRP 895

Query: 559 NMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLK 594
            + G +         LLT  +F L+     FFSSL+
Sbjct: 896 EIGGELGGPR--TAKLLTSCLFVLLWLLYIFFSSLE 929


>gi|163914371 solute carrier family 8 (sodium/calcium exchanger),
           member 1 isoform C [Homo sapiens]
          Length = 960

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 16/96 (16%)

Query: 507 ILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVF--------YYARRS 558
           + L +G   SIA  Y   +GE ++      +S G+    + L+++F         Y RR 
Sbjct: 865 VFLGIGVAWSIAAIYHAANGEQFK------VSPGTLAFSVTLFTIFAFINVGVLLYRRRP 918

Query: 559 NMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLK 594
            + G +         LLT  +F L+     FFSSL+
Sbjct: 919 EIGGELGGPR--TAKLLTSCLFVLLWLLYIFFSSLE 952


>gi|163914369 solute carrier family 8 (sodium/calcium exchanger),
           member 1 isoform B [Homo sapiens]
          Length = 968

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 16/96 (16%)

Query: 507 ILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVF--------YYARRS 558
           + L +G   SIA  Y   +GE ++      +S G+    + L+++F         Y RR 
Sbjct: 873 VFLGIGVAWSIAAIYHAANGEQFK------VSPGTLAFSVTLFTIFAFINVGVLLYRRRP 926

Query: 559 NMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLK 594
            + G +         LLT  +F L+     FFSSL+
Sbjct: 927 EIGGELGGPR--TAKLLTSCLFVLLWLLYIFFSSLE 960


>gi|30581137 phosphatidylinositol glycan anchor biosynthesis, class
           Z [Homo sapiens]
          Length = 579

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 34/139 (24%), Positives = 55/139 (39%), Gaps = 20/139 (14%)

Query: 372 WVWNIILTTSLFSVPFFLTWSVVNSVHW-ANGSTQALPATTILLLLTVWLLVGFPLTVIG 430
           W+   I+    F+ P FL ++VV    W   G+T   P    L    + LL G  LT   
Sbjct: 214 WLLGGIVAAGFFNRPTFLAFAVVPLYLWGTRGATN--PGLKSLTREALVLLPGAALT--A 269

Query: 431 GIFGKNNASPFDAPCRTKNIA--------REIPPQPWYK----STVIHMTVGGFLPFSAI 478
            +F   ++  F +P  ++N+           + PQ   +    + + H+ V GFL F  +
Sbjct: 270 AVFVATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVL 329

Query: 479 SVELYYIFATVWGREQYTL 497
             +        W R Q  L
Sbjct: 330 HAQ---ALQAAWQRLQVGL 345


>gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]
          Length = 490

 Score = 30.0 bits (66), Expect = 6.4
 Identities = 36/127 (28%), Positives = 49/127 (38%), Gaps = 30/127 (23%)

Query: 469 VGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGED 528
           V G L F  +S  L    + VWGR+ + L  + F           C  I L         
Sbjct: 80  VKGLLSF--LSAPLIGALSDVWGRKSFLLLTVFF----------TCAPIPLMKIS----- 122

Query: 529 YRWWWRSVLSVGSTGLFIFLYS-VFYYA-------RRSNMSGAVQTVEFFGYSLLTGYVF 580
             WW+ +V+SV  +G+F   +S VF Y         RS   G V     F  SL+T    
Sbjct: 123 -PWWYFAVISV--SGVFAVTFSVVFAYVADITQEHERSMAYGLVSAT--FAASLVTSPAI 177

Query: 581 FLMLGTI 587
              LG +
Sbjct: 178 GAYLGRV 184


>gi|57164951 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform b [Homo sapiens]
          Length = 341

 Score = 30.0 bits (66), Expect = 6.4
 Identities = 35/127 (27%), Positives = 56/127 (44%), Gaps = 16/127 (12%)

Query: 307 LCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQ 366
           +C+V+G  +     G GI +  L     V RH     A ILL +L  C+S  + ++  R 
Sbjct: 165 ICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPL---AWILLLSLIVCVSTQI-NYLNRA 220

Query: 367 IGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPL 426
           +     ++N  + T ++ V  F T SV+          Q +P   +     +  L GF  
Sbjct: 221 LD----IFNTSIVTPIYYV--FFTTSVLTCSAILFKEWQDMPVDDV-----IGTLSGF-F 268

Query: 427 TVIGGIF 433
           T+I GIF
Sbjct: 269 TIIVGIF 275


>gi|57013272 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score = 30.0 bits (66), Expect = 6.4
 Identities = 35/127 (27%), Positives = 56/127 (44%), Gaps = 16/127 (12%)

Query: 307 LCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQ 366
           +C+V+G  +     G GI +  L     V RH     A ILL +L  C+S  + ++  R 
Sbjct: 184 ICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPL---AWILLLSLIVCVSTQI-NYLNRA 239

Query: 367 IGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPL 426
           +     ++N  + T ++ V  F T SV+          Q +P   +     +  L GF  
Sbjct: 240 LD----IFNTSIVTPIYYV--FFTTSVLTCSAILFKEWQDMPVDDV-----IGTLSGF-F 287

Query: 427 TVIGGIF 433
           T+I GIF
Sbjct: 288 TIIVGIF 294


>gi|57164953 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score = 30.0 bits (66), Expect = 6.4
 Identities = 35/127 (27%), Positives = 56/127 (44%), Gaps = 16/127 (12%)

Query: 307 LCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQ 366
           +C+V+G  +     G GI +  L     V RH     A ILL +L  C+S  + ++  R 
Sbjct: 184 ICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPL---AWILLLSLIVCVSTQI-NYLNRA 239

Query: 367 IGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPL 426
           +     ++N  + T ++ V  F T SV+          Q +P   +     +  L GF  
Sbjct: 240 LD----IFNTSIVTPIYYV--FFTTSVLTCSAILFKEWQDMPVDDV-----IGTLSGF-F 287

Query: 427 TVIGGIF 433
           T+I GIF
Sbjct: 288 TIIVGIF 294


>gi|57013274 non imprinted in Prader-Willi/Angelman syndrome 2
           isoform a [Homo sapiens]
          Length = 360

 Score = 30.0 bits (66), Expect = 6.4
 Identities = 35/127 (27%), Positives = 56/127 (44%), Gaps = 16/127 (12%)

Query: 307 LCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQ 366
           +C+V+G  +     G GI +  L     V RH     A ILL +L  C+S  + ++  R 
Sbjct: 184 ICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPL---AWILLLSLIVCVSTQI-NYLNRA 239

Query: 367 IGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPL 426
           +     ++N  + T ++ V  F T SV+          Q +P   +     +  L GF  
Sbjct: 240 LD----IFNTSIVTPIYYV--FFTTSVLTCSAILFKEWQDMPVDDV-----IGTLSGF-F 287

Query: 427 TVIGGIF 433
           T+I GIF
Sbjct: 288 TIIVGIF 294


>gi|56682974 zinc finger, DHHC domain containing 9 [Homo sapiens]
          Length = 364

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 13/60 (21%), Positives = 35/60 (58%)

Query: 528 DYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTI 587
           +YR+++  +LS+    +++F +++ Y A +S   G ++T++    ++L   + F  L ++
Sbjct: 180 NYRYFYLFILSLSLLTIYVFAFNIVYVALKSLKIGFLETLKETPGTVLEVLICFFTLWSV 239


>gi|56682972 zinc finger, DHHC domain containing 9 [Homo sapiens]
          Length = 364

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 13/60 (21%), Positives = 35/60 (58%)

Query: 528 DYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTI 587
           +YR+++  +LS+    +++F +++ Y A +S   G ++T++    ++L   + F  L ++
Sbjct: 180 NYRYFYLFILSLSLLTIYVFAFNIVYVALKSLKIGFLETLKETPGTVLEVLICFFTLWSV 239


>gi|31542246 kelch-like 36 [Homo sapiens]
          Length = 616

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 13/79 (16%)

Query: 91  SLYEIRFRENVEKRILCHMQLSSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGF 150
           S++ I  RE  +K +    +L  A    L+  ++ LY  E V+D     G + Y+ E+  
Sbjct: 73  SMFTIGMREAFQKEV----ELIGASYIGLKAVVDFLYGGELVLDG----GNIDYVLET-- 122

Query: 151 LPHSHKIGLWTHLDFHLEF 169
              +H + +WT +DF  E+
Sbjct: 123 ---AHLLQIWTVVDFCCEY 138


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.143    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,862,240
Number of Sequences: 37866
Number of extensions: 1031476
Number of successful extensions: 2755
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2725
Number of HSP's gapped (non-prelim): 31
length of query: 606
length of database: 18,247,518
effective HSP length: 108
effective length of query: 498
effective length of database: 14,157,990
effective search space: 7050679020
effective search space used: 7050679020
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.