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Search of human proteins with 21327705
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21327705 stratum corneum chymotryptic enzyme preproprotein
[Homo sapiens]
(253 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 530 e-151
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 530 e-151
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 237 8e-63
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 237 8e-63
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 237 8e-63
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 226 2e-59
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 224 4e-59
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 224 7e-59
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 221 4e-58
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 221 4e-58
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 221 4e-58
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 219 1e-57
gi|11496281 kallikrein 13 precursor [Homo sapiens] 219 2e-57
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 216 2e-56
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 213 1e-55
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 213 1e-55
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 213 1e-55
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 213 2e-55
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 207 9e-54
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 207 9e-54
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 204 8e-53
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 199 3e-51
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 199 3e-51
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 197 6e-51
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 194 6e-50
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 193 1e-49
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 192 3e-49
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 192 3e-49
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 187 1e-47
gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 170 1e-42
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 530 bits (1364), Expect = e-151
Identities = 253/253 (100%), Positives = 253/253 (100%)
Query: 1 MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
Sbjct: 1 MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
Query: 61 NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
Sbjct: 61 NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120
Query: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
Sbjct: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
Query: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
Sbjct: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240
Query: 241 FTKWINDTMKKHR 253
FTKWINDTMKKHR
Sbjct: 241 FTKWINDTMKKHR 253
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 530 bits (1364), Expect = e-151
Identities = 253/253 (100%), Positives = 253/253 (100%)
Query: 1 MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
Sbjct: 1 MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
Query: 61 NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
Sbjct: 61 NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120
Query: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
Sbjct: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
Query: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
Sbjct: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240
Query: 241 FTKWINDTMKKHR 253
FTKWINDTMKKHR
Sbjct: 241 FTKWINDTMKKHR 253
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 237 bits (604), Expect = 8e-63
Identities = 114/238 (47%), Positives = 157/238 (65%), Gaps = 9/238 (3%)
Query: 21 AGEEAQGD----KIIDGAPCARGSHPWQVA-LLSGNQLHCGGVLVNERWVLTAAHCKMNE 75
AGE+A+ D +II+G+ C + PWQ A LL NQL+CG VLV+ +W+LTAAHC+
Sbjct: 54 AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKV 113
Query: 76 YTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVR 132
+ V LG +L + Q + KS HPGYS H NDLML+KLN + R + V+ +
Sbjct: 114 FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPIN 173
Query: 133 LPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAG 192
+ S C GT C VSGWGTT SP V FP L C+++ ++S + C Y ++++M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233
Query: 193 IPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250
+ +++C GDSGGP+VC G+LQGLVSWG +PC +PN PGVYT +CKFTKWI +T++
Sbjct: 234 -DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 237 bits (604), Expect = 8e-63
Identities = 114/238 (47%), Positives = 157/238 (65%), Gaps = 9/238 (3%)
Query: 21 AGEEAQGD----KIIDGAPCARGSHPWQVA-LLSGNQLHCGGVLVNERWVLTAAHCKMNE 75
AGE+A+ D +II+G+ C + PWQ A LL NQL+CG VLV+ +W+LTAAHC+
Sbjct: 54 AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKV 113
Query: 76 YTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVR 132
+ V LG +L + Q + KS HPGYS H NDLML+KLN + R + V+ +
Sbjct: 114 FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPIN 173
Query: 133 LPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAG 192
+ S C GT C VSGWGTT SP V FP L C+++ ++S + C Y ++++M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233
Query: 193 IPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250
+ +++C GDSGGP+VC G+LQGLVSWG +PC +PN PGVYT +CKFTKWI +T++
Sbjct: 234 -DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 237 bits (604), Expect = 8e-63
Identities = 114/238 (47%), Positives = 157/238 (65%), Gaps = 9/238 (3%)
Query: 21 AGEEAQGD----KIIDGAPCARGSHPWQVA-LLSGNQLHCGGVLVNERWVLTAAHCKMNE 75
AGE+A+ D +II+G+ C + PWQ A LL NQL+CG VLV+ +W+LTAAHC+
Sbjct: 54 AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKV 113
Query: 76 YTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVR 132
+ V LG +L + Q + KS HPGYS H NDLML+KLN + R + V+ +
Sbjct: 114 FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPIN 173
Query: 133 LPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAG 192
+ S C GT C VSGWGTT SP V FP L C+++ ++S + C Y ++++M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233
Query: 193 IPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250
+ +++C GDSGGP+VC G+LQGLVSWG +PC +PN PGVYT +CKFTKWI +T++
Sbjct: 234 -DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 226 bits (575), Expect = 2e-59
Identities = 110/250 (44%), Positives = 150/250 (60%), Gaps = 8/250 (3%)
Query: 5 LLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSG--NQLHCGGVLVNE 62
LL LQ+L +++ E +KII G C R S PWQ ALL+G + CGG L++
Sbjct: 20 LLTALQVLAIAMTQSQEDE----NKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSG 75
Query: 63 RWVLTAAHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120
+WV+TAAHC V LG L A Q ++ + HP Y+++TH NDLML++L
Sbjct: 76 QWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQ 135
Query: 121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180
AR+ V+ + + C PGT+C VSGWGT +SP +P+ L CV++ + + C K Y
Sbjct: 136 PARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAY 195
Query: 181 KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240
+ M+CAG+P K++C GDSGGPLVCRG LQGLVSWG C P PGVYT +CK
Sbjct: 196 PRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCK 255
Query: 241 FTKWINDTMK 250
+ WI +TM+
Sbjct: 256 YRSWIEETMR 265
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 224 bits (572), Expect = 4e-59
Identities = 117/243 (48%), Positives = 145/243 (59%), Gaps = 11/243 (4%)
Query: 11 ILLLSLALETAGEE-AQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAA 69
+ LL L AG AQ DK++ G C S PWQ AL G QL CGGVLV WVLTAA
Sbjct: 13 MFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAA 72
Query: 70 HCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST---QTHVNDLMLVKLNSQARL 124
HCK +YTV LG +L ++ Q I +S HP Y++ + H +DLML++L QA L
Sbjct: 73 HCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASL 132
Query: 125 SSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLL 184
S VK + L C PG CTVSGWGT TSP FP L C +VK+ + C Y +
Sbjct: 133 GSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQI 192
Query: 185 ENSMLCAGIPDSKKNA--CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242
+ M+CAG S K A C GDSGGPLVC G LQG+ SWG+ PCG+ + PGVYT +C++
Sbjct: 193 TDGMVCAG---SSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYL 249
Query: 243 KWI 245
WI
Sbjct: 250 DWI 252
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 224 bits (570), Expect = 7e-59
Identities = 112/228 (49%), Positives = 139/228 (60%), Gaps = 10/228 (4%)
Query: 25 AQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT 84
AQ DK++ G C S PWQ AL G QL CGGVLV WVLTAAHCK +YTV LG +
Sbjct: 73 AQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHS 132
Query: 85 LGDRRA--QRIKASKSFRHPGYST---QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP 139
L ++ Q I +S HP Y++ + H +DLML++L QA L S VK + L C
Sbjct: 133 LQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQ 192
Query: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199
PG CTVSGWGT TSP FP L C +VK+ + C Y + + M+CAG S K
Sbjct: 193 PGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAG---SSKG 249
Query: 200 A--CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245
A C GDSGGPLVC G LQG+ SWG+ PCG+ + PGVYT +C++ WI
Sbjct: 250 ADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 297
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 221 bits (564), Expect = 4e-58
Identities = 108/250 (43%), Positives = 149/250 (59%), Gaps = 9/250 (3%)
Query: 9 LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
LQ++LL+LA G E +II G C S PWQ AL +L CG L+ RW+LTA
Sbjct: 4 LQLILLALATGLVGGET---RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60
Query: 69 AHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST----QTHVNDLMLVKLNSQA 122
AHC Y VHLG L Q A++SF HPG++ + H ND+MLVK+ S
Sbjct: 61 AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 120
Query: 123 RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182
++ V+ + L SRC GT+C +SGWG+T+SP + P L C ++ +I Q C Y
Sbjct: 121 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180
Query: 183 LLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242
+ ++M+CA + + K++C GDSGGPLVC +LQG++SWG PC PGVYT+VCK+
Sbjct: 181 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 240
Query: 243 KWINDTMKKH 252
WI +TMK +
Sbjct: 241 DWIQETMKNN 250
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 221 bits (564), Expect = 4e-58
Identities = 108/250 (43%), Positives = 149/250 (59%), Gaps = 9/250 (3%)
Query: 9 LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
LQ++LL+LA G E +II G C S PWQ AL +L CG L+ RW+LTA
Sbjct: 36 LQLILLALATGLVGGET---RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92
Query: 69 AHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST----QTHVNDLMLVKLNSQA 122
AHC Y VHLG L Q A++SF HPG++ + H ND+MLVK+ S
Sbjct: 93 AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 152
Query: 123 RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182
++ V+ + L SRC GT+C +SGWG+T+SP + P L C ++ +I Q C Y
Sbjct: 153 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212
Query: 183 LLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242
+ ++M+CA + + K++C GDSGGPLVC +LQG++SWG PC PGVYT+VCK+
Sbjct: 213 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 272
Query: 243 KWINDTMKKH 252
WI +TMK +
Sbjct: 273 DWIQETMKNN 282
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 221 bits (564), Expect = 4e-58
Identities = 108/250 (43%), Positives = 149/250 (59%), Gaps = 9/250 (3%)
Query: 9 LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
LQ++LL+LA G E +II G C S PWQ AL +L CG L+ RW+LTA
Sbjct: 4 LQLILLALATGLVGGET---RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60
Query: 69 AHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST----QTHVNDLMLVKLNSQA 122
AHC Y VHLG L Q A++SF HPG++ + H ND+MLVK+ S
Sbjct: 61 AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 120
Query: 123 RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182
++ V+ + L SRC GT+C +SGWG+T+SP + P L C ++ +I Q C Y
Sbjct: 121 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180
Query: 183 LLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242
+ ++M+CA + + K++C GDSGGPLVC +LQG++SWG PC PGVYT+VCK+
Sbjct: 181 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 240
Query: 243 KWINDTMKKH 252
WI +TMK +
Sbjct: 241 DWIQETMKNN 250
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 219 bits (559), Expect = 1e-57
Identities = 110/240 (45%), Positives = 151/240 (62%), Gaps = 7/240 (2%)
Query: 16 LALETAGEEAQGD--KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKM 73
L L AG G +II+G C+ S PWQ AL+ N+L C GVLV+ +WVL+AAHC
Sbjct: 15 LILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ 74
Query: 74 NEYTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKK 130
N YT+ LG +L + +Q ++AS S RHP Y+ NDLML+KL+ S ++
Sbjct: 75 NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRS 134
Query: 131 VRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLC 190
+ + S+C G +C VSGWG + + P+ L CV+V ++S + C+K+Y L SM C
Sbjct: 135 ISIASQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFC 192
Query: 191 AGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250
AG +K++CNGDSGGPL+C G LQGLVS+G PCGQ PGVYT +CKFT+WI T++
Sbjct: 193 AGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 219 bits (558), Expect = 2e-57
Identities = 116/263 (44%), Positives = 161/263 (61%), Gaps = 18/263 (6%)
Query: 8 PLQILLLSLALETAGEEAQ-GDKIID----------GAPCARGSHPWQVALLSGNQLHCG 56
PL +++ SL L +G +Q K+++ G C S PWQ ALL +L CG
Sbjct: 3 PLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCG 62
Query: 57 GVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYS-TQTHVN-- 111
GVLV+ +WVLTAAHC V+LG LG A Q + S HP Y + TH+N
Sbjct: 63 GVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHD 122
Query: 112 -DLMLVKLNSQARLSSMVKKVRLPSRCE-PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVK 169
D+ML++L S +L+ ++ + L PGTTC VSGWGTTTSP V +P L C +++
Sbjct: 123 HDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQ 182
Query: 170 LISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQP 229
L S ++C +VY + ++MLCAG + K++C GDSGGPLVC TL G+VSWG FPCGQP
Sbjct: 183 LRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQP 242
Query: 230 NDPGVYTQVCKFTKWINDTMKKH 252
+ PGVYT+V ++ WI +T++K+
Sbjct: 243 DRPGVYTRVSRYVLWIRETIRKY 265
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 216 bits (550), Expect = 2e-56
Identities = 112/254 (44%), Positives = 146/254 (57%), Gaps = 13/254 (5%)
Query: 12 LLLSLALETAGEEAQ-GDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAH 70
LLL+L+ A AQ GDK+++G CA S PWQVAL + +CG L++ WVL+AAH
Sbjct: 3 LLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
Query: 71 CKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128
C+ V LG L R Q S+ HP Y ++H ND+ML++L ARL+ V
Sbjct: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQV 122
Query: 129 KKVRLPSRCEPPGTTCTVSGWG--------TTTSP--DVTFPSDLMCVDVKLISPQDCTK 178
+ LP+RC PG C VSGWG T SP V+ P L C ++ +IS C K
Sbjct: 123 RPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDK 182
Query: 179 VYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQV 238
Y L N+M+CAG +C GDSGGPLVC G LQG+VSWG PC PGVYT+V
Sbjct: 183 SYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKV 242
Query: 239 CKFTKWINDTMKKH 252
C + +WI +TMK++
Sbjct: 243 CHYLEWIRETMKRN 256
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 213 bits (542), Expect = 1e-55
Identities = 108/264 (40%), Positives = 154/264 (58%), Gaps = 14/264 (5%)
Query: 2 ARSLLLPLQILLLSLALETAGEEAQGDKIID----GAPCARGSHPWQVALLSGNQLHCGG 57
AR+L L +L+ L A Q D +D G+PCARGS PWQV+L +G HC G
Sbjct: 14 ARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAG 73
Query: 58 VLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIK-ASKSFRHPGYST--------QT 108
VLV++ WVLTAAHC +G D L + ++++ ++S HP Y +T
Sbjct: 74 VLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGPILPRRT 133
Query: 109 HVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDV 168
+DLML+KL L V+ ++LP RC PG C V+GWGTT + V + L C +
Sbjct: 134 DEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSI 193
Query: 169 KLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQ 228
++SP++C Y ++ N+M+CAG+ D ++ C DSGGPLVC TLQG++SWG +PCG
Sbjct: 194 TILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGS 252
Query: 229 PNDPGVYTQVCKFTKWINDTMKKH 252
P VYTQ+CK+ WIN ++ +
Sbjct: 253 AQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 213 bits (542), Expect = 1e-55
Identities = 108/264 (40%), Positives = 154/264 (58%), Gaps = 14/264 (5%)
Query: 2 ARSLLLPLQILLLSLALETAGEEAQGDKIID----GAPCARGSHPWQVALLSGNQLHCGG 57
AR+L L +L+ L A Q D +D G+PCARGS PWQV+L +G HC G
Sbjct: 14 ARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAG 73
Query: 58 VLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIK-ASKSFRHPGYST--------QT 108
VLV++ WVLTAAHC +G D L + ++++ ++S HP Y +T
Sbjct: 74 VLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGPILPRRT 133
Query: 109 HVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDV 168
+DLML+KL L V+ ++LP RC PG C V+GWGTT + V + L C +
Sbjct: 134 DEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSI 193
Query: 169 KLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQ 228
++SP++C Y ++ N+M+CAG+ D ++ C DSGGPLVC TLQG++SWG +PCG
Sbjct: 194 TILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGS 252
Query: 229 PNDPGVYTQVCKFTKWINDTMKKH 252
P VYTQ+CK+ WIN ++ +
Sbjct: 253 AQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 213 bits (542), Expect = 1e-55
Identities = 108/264 (40%), Positives = 154/264 (58%), Gaps = 14/264 (5%)
Query: 2 ARSLLLPLQILLLSLALETAGEEAQGDKIID----GAPCARGSHPWQVALLSGNQLHCGG 57
AR+L L +L+ L A Q D +D G+PCARGS PWQV+L +G HC G
Sbjct: 14 ARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAG 73
Query: 58 VLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIK-ASKSFRHPGYST--------QT 108
VLV++ WVLTAAHC +G D L + ++++ ++S HP Y +T
Sbjct: 74 VLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGPILPRRT 133
Query: 109 HVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDV 168
+DLML+KL L V+ ++LP RC PG C V+GWGTT + V + L C +
Sbjct: 134 DEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSI 193
Query: 169 KLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQ 228
++SP++C Y ++ N+M+CAG+ D ++ C DSGGPLVC TLQG++SWG +PCG
Sbjct: 194 TILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGS 252
Query: 229 PNDPGVYTQVCKFTKWINDTMKKH 252
P VYTQ+CK+ WIN ++ +
Sbjct: 253 AQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 213 bits (541), Expect = 2e-55
Identities = 115/258 (44%), Positives = 152/258 (58%), Gaps = 16/258 (6%)
Query: 1 MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
M S+ L L +L LS +A KI +G C R S PWQV L G L CGGVL+
Sbjct: 1 MGLSIFLLLCVLGLS--------QAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLI 52
Query: 61 NERWVLTAAHCKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGY--STQTHVNDLMLV 116
+ RWVLTAAHC + Y V LG +L D Q + S HPGY ++ +H +DL L+
Sbjct: 53 DHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLL 112
Query: 117 KLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC 176
+L R++S V+ + LP+ C GT C VSGWG T P FP L C+++ ++S C
Sbjct: 113 RLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATC 172
Query: 177 TKVYKDLLENSMLCA-GIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTF-PCGQPNDPGV 234
VY + ++M+CA G+P ++AC GDSGGPLVC G LQGLVSWG+ PCGQ PGV
Sbjct: 173 HGVYPGRITSNMVCAGGVPG--QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGV 230
Query: 235 YTQVCKFTKWINDTMKKH 252
YT +CK+ WI M+ +
Sbjct: 231 YTYICKYVDWIRMIMRNN 248
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 207 bits (526), Expect = 9e-54
Identities = 99/241 (41%), Positives = 142/241 (58%), Gaps = 4/241 (1%)
Query: 12 LLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC 71
L++ L+L A + +K++ G PC + SHP+Q AL + L CGGVL++ WVLTAAHC
Sbjct: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63
Query: 72 KMNEYTVHLGSDTLGDRRAQRIKAS--KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVK 129
K V LG L R + + ++S ++ HP Y +H D+ML++L A+LS +++
Sbjct: 64 KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ 123
Query: 130 KVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSML 189
+ L C T+C + GWG T D FP + C + L+S ++C Y + +ML
Sbjct: 124 PLPLERDCSANTTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNML 181
Query: 190 CAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
CAG K++C GDSGGPLVC L+GLVSWG PCG PGVYT VC++T WI T+
Sbjct: 182 CAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241
Query: 250 K 250
+
Sbjct: 242 Q 242
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 207 bits (526), Expect = 9e-54
Identities = 99/241 (41%), Positives = 142/241 (58%), Gaps = 4/241 (1%)
Query: 12 LLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC 71
L++ L+L A + +K++ G PC + SHP+Q AL + L CGGVL++ WVLTAAHC
Sbjct: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63
Query: 72 KMNEYTVHLGSDTLGDRRAQRIKAS--KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVK 129
K V LG L R + + ++S ++ HP Y +H D+ML++L A+LS +++
Sbjct: 64 KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ 123
Query: 130 KVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSML 189
+ L C T+C + GWG T D FP + C + L+S ++C Y + +ML
Sbjct: 124 PLPLERDCSANTTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNML 181
Query: 190 CAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
CAG K++C GDSGGPLVC L+GLVSWG PCG PGVYT VC++T WI T+
Sbjct: 182 CAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241
Query: 250 K 250
+
Sbjct: 242 Q 242
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 204 bits (518), Expect = 8e-53
Identities = 112/248 (45%), Positives = 146/248 (58%), Gaps = 16/248 (6%)
Query: 1 MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV 60
M S+ L L +L LS +A KI +G C R S PWQV L G L CGGVL+
Sbjct: 1 MGLSIFLLLCVLGLS--------QAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLI 52
Query: 61 NERWVLTAAHCKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGY--STQTHVNDLMLV 116
+ RWVLTAAHC + Y V LG +L D Q + S HPGY ++ +H +DL L+
Sbjct: 53 DHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLL 112
Query: 117 KLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC 176
+L R++S V+ + LP+ C GT C VSGWG T P FP L C+++ ++S C
Sbjct: 113 RLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATC 172
Query: 177 TKVYKDLLENSMLCA-GIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTF-PCGQPNDPGV 234
VY + ++M+CA G+P ++AC GDSGGPLVC G LQGLVSWG+ PCGQ PGV
Sbjct: 173 HGVYPGRITSNMVCAGGVPG--QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGV 230
Query: 235 YTQVCKFT 242
YT +C T
Sbjct: 231 YTYICNST 238
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 199 bits (505), Expect = 3e-51
Identities = 99/241 (41%), Positives = 141/241 (58%), Gaps = 4/241 (1%)
Query: 11 ILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAH 70
++L +A A DKI+ G C S P+QV+L SG CGG L+NE+WV++A H
Sbjct: 5 LILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHF-CGGSLINEQWVVSAGH 63
Query: 71 CKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128
C + V LG + + Q I A+K RHP Y +T ND+ML+KL+S+A +++ V
Sbjct: 64 CYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARV 123
Query: 129 KKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSM 188
+ LP+ GT C +SGWG T S +P +L C+D ++S C Y + ++M
Sbjct: 124 STISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNM 183
Query: 189 LCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248
C G + K++C GDSGGP+VC G LQG+VSWG C Q N PGVYT+V + KWI +T
Sbjct: 184 FCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNT 242
Query: 249 M 249
+
Sbjct: 243 I 243
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 199 bits (505), Expect = 3e-51
Identities = 104/258 (40%), Positives = 146/258 (56%), Gaps = 17/258 (6%)
Query: 12 LLLSLALETAGEEAQG---DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
L+L LAL G A +I+ G C + S PWQ AL + CGG+LV+ +WVLTA
Sbjct: 4 LVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTA 63
Query: 69 AHCKMNEYTVHLGSDTLGD--RRAQRIKASKSFRHPGYST-----------QTHVNDLML 115
AHC + Y + LG L D AQ + S+SF HPG++ + + +DLML
Sbjct: 64 AHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLML 123
Query: 116 VKLNSQA-RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQ 174
++L A ++ VK V LP+ G+TC SGWG+ + +FP DL CVD+K++
Sbjct: 124 LRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPND 183
Query: 175 DCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGV 234
+C K + + + MLC G + K+ C GDSGGPL+C G LQG+ SWG PCG PN P V
Sbjct: 184 ECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSV 243
Query: 235 YTQVCKFTKWINDTMKKH 252
+V + KWI DT+ ++
Sbjct: 244 AVRVLSYVKWIEDTIAEN 261
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 197 bits (502), Expect = 6e-51
Identities = 105/254 (41%), Positives = 141/254 (55%), Gaps = 16/254 (6%)
Query: 12 LLLSLALE---TAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
L+LS+AL T +I+ G C + S PWQVA+ S HCGGVLV+ +WVLTA
Sbjct: 4 LVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTA 63
Query: 69 AHCKMNEYTVHLGSDTLGDRR--AQRIKASKSFRHPGYST-----------QTHVNDLML 115
AHC V LG L + QR+ S SF HP Y+ + +DLML
Sbjct: 64 AHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLML 123
Query: 116 VKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQD 175
++L+ A+++ +VK + LP++ GTTC SGWG+ + P L CV + L+S
Sbjct: 124 LRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDM 183
Query: 176 CTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVY 235
C + Y + + MLCAG+ K+ C GDSGGPLVC G LQG+ SWG PC P P VY
Sbjct: 184 CARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVY 243
Query: 236 TQVCKFTKWINDTM 249
T+V + KWI DT+
Sbjct: 244 TKVVHYRKWIKDTI 257
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 194 bits (493), Expect = 6e-50
Identities = 98/243 (40%), Positives = 142/243 (58%), Gaps = 4/243 (1%)
Query: 9 LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
L ++L +A A DKI+ G C S P+QV+L SG CGG L++E+WV++A
Sbjct: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSA 61
Query: 69 AHCKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSS 126
HC + V LG + + Q I A+K RHP Y+++T ND++L+KL+S A ++S
Sbjct: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINS 121
Query: 127 MVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLEN 186
V + LP+ GT +SGWG T S +P +L C+D ++S +C Y + N
Sbjct: 122 RVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITN 181
Query: 187 SMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246
+M C G + K++C GDSGGP+V G LQG+VSWG + C Q N PGVYT+V + WI
Sbjct: 182 NMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIK 240
Query: 247 DTM 249
DT+
Sbjct: 241 DTI 243
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 193 bits (491), Expect = 1e-49
Identities = 97/245 (39%), Positives = 133/245 (54%), Gaps = 6/245 (2%)
Query: 12 LLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC 71
LL +L AG + I C S PWQ L +L CG L+++RW+LTAAHC
Sbjct: 5 LLCALLSLLAGHGWADTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHC 64
Query: 72 KMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGY----STQTHVNDLMLVKLNSQARLS 125
+ V LG L + Q + + F HPG+ S H +D+ML++L QARLS
Sbjct: 65 RKPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLS 124
Query: 126 SMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLE 185
V+ + L C PG C +SGWG +SP FP L C ++ ++ + C Y +
Sbjct: 125 PAVQPLNLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHIS 184
Query: 186 NSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245
+SMLCAG+ + + +C GDSGGPLVC GTL G+VS G PC +P P VYT VC + WI
Sbjct: 185 DSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWI 244
Query: 246 NDTMK 250
+ M+
Sbjct: 245 QEIME 249
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 192 bits (487), Expect = 3e-49
Identities = 95/224 (42%), Positives = 133/224 (59%), Gaps = 4/224 (1%)
Query: 28 DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86
DKI+ G C S P+QV+L SG+ CGG L++E+WV++AAHC V LG +
Sbjct: 79 DKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKV 137
Query: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145
+ Q I A+K RHP Y+ T ND+ML+KL+S A +++ V + LP+ GT C
Sbjct: 138 LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECL 197
Query: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205
+SGWG T S +P +L C+D +++ +C Y + NSM C G + K++C DS
Sbjct: 198 ISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDS 257
Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
GGP+VC G LQG+VSWG C N PGVYT+V + WI DT+
Sbjct: 258 GGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 300
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 192 bits (487), Expect = 3e-49
Identities = 95/224 (42%), Positives = 133/224 (59%), Gaps = 4/224 (1%)
Query: 28 DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86
DKI+ G C S P+QV+L SG+ CGG L++E+WV++AAHC V LG +
Sbjct: 22 DKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKV 80
Query: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145
+ Q I A+K RHP Y+ T ND+ML+KL+S A +++ V + LP+ GT C
Sbjct: 81 LEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECL 140
Query: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205
+SGWG T S +P +L C+D +++ +C Y + NSM C G + K++C DS
Sbjct: 141 ISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDS 200
Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
GGP+VC G LQG+VSWG C N PGVYT+V + WI DT+
Sbjct: 201 GGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 243
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 187 bits (474), Expect = 1e-47
Identities = 98/234 (41%), Positives = 132/234 (56%), Gaps = 13/234 (5%)
Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--G 86
+I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC N+ + LG +L
Sbjct: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83
Query: 87 DRRAQRIKASKSFRHPGYSTQTHVN-----------DLMLVKLNSQARLSSMVKKVRLPS 135
+ Q + S SF HP Y N DLML++L+ A L+ VK + LP+
Sbjct: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143
Query: 136 RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPD 195
+ GTTC SGWG+ + P L CVD+ +IS C +V+ + MLCAG
Sbjct: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203
Query: 196 SKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
K+ C+GDSGGPLVC G LQG+ SWG+ PC P P +YT+V + KWI DT+
Sbjct: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257
>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
sapiens]
Length = 218
Score = 170 bits (431), Expect = 1e-42
Identities = 89/221 (40%), Positives = 120/221 (54%), Gaps = 30/221 (13%)
Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDR 88
+I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC
Sbjct: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC----------------- 66
Query: 89 RAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSG 148
R PG + +DLML++L+ A L+ VK + LP++ GTTC SG
Sbjct: 67 ----------IRKPGDDSS---HDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASG 113
Query: 149 WGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGP 208
WG+ + P L CVD+ +IS C +V+ + MLCAG K+ C+GDSGGP
Sbjct: 114 WGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGP 173
Query: 209 LVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
LVC G LQG+ SWG+ PC P P +YT+V + KWI DT+
Sbjct: 174 LVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 214
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,711,592
Number of Sequences: 37866
Number of extensions: 498972
Number of successful extensions: 1669
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1057
Number of HSP's gapped (non-prelim): 196
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.