Search of human proteins with 21071010

Search of human proteins with 21071010

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21071010 transcobalamin II precursor [Homo sapiens]
         (427 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21071010 transcobalamin II precursor [Homo sapiens]                860   0.0  
gi|21071008 transcobalamin I precursor [Homo sapiens]                 130   2e-30
gi|32189398 gastric intrinsic factor (vitamin B synthesis) precu...   102   9e-22
gi|122937247 unc-13 homolog A [Homo sapiens]                           32   0.84 
gi|14195616 protocadherin beta 9 precursor [Homo sapiens]              30   3.2  
gi|15529996 son of sevenless homolog 1 [Homo sapiens]                  29   9.3  
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           29   9.3  

>gi|21071010 transcobalamin II precursor [Homo sapiens]
          Length = 427

 Score =  860 bits (2222), Expect = 0.0
 Identities = 427/427 (100%), Positives = 427/427 (100%)

Query: 1   MRHLGAFLFLLGVLGALTEMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRL 60
           MRHLGAFLFLLGVLGALTEMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRL
Sbjct: 1   MRHLGAFLFLLGVLGALTEMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRL 60

Query: 61  SSLQAGTKEDLYLHSLKLGYQQCLLGSAFSEDDGDCQGKPSMGQLALYLLALRANCEFVR 120
           SSLQAGTKEDLYLHSLKLGYQQCLLGSAFSEDDGDCQGKPSMGQLALYLLALRANCEFVR
Sbjct: 61  SSLQAGTKEDLYLHSLKLGYQQCLLGSAFSEDDGDCQGKPSMGQLALYLLALRANCEFVR 120

Query: 121 GHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLL 180
           GHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLL
Sbjct: 121 GHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLL 180

Query: 181 YAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVREEILKAQTPEGHF 240
           YAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVREEILKAQTPEGHF
Sbjct: 181 YAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVREEILKAQTPEGHF 240

Query: 241 GNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKT 300
           GNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKT
Sbjct: 241 GNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKT 300

Query: 301 YIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLK 360
           YIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLK
Sbjct: 301 YIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLK 360

Query: 361 KAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETI 420
           KAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETI
Sbjct: 361 KAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETI 420

Query: 421 ELRLVSW 427
           ELRLVSW
Sbjct: 421 ELRLVSW 427


>gi|21071008 transcobalamin I precursor [Homo sapiens]
          Length = 433

 Score =  130 bits (328), Expect = 2e-30
 Identities = 129/445 (28%), Positives = 204/445 (45%), Gaps = 50/445 (11%)

Query: 4   LGAFLFLLGVLGALTEMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRLSSL 63
           +G  LF   +   L E+CE+ E +   ++ L   ++          +N  + + L+L  +
Sbjct: 10  VGLLLFSF-IPSQLCEICEVSEENYIRLKPLLNTMIQSNYNRGTSAVN--VVLSLKLVGI 66

Query: 64  QAGTKEDLYLHSLKLGYQQCLLGSAFSEDDGDCQGKPSMGQLALYLLALRA--NCE---F 118
           Q  T     +  +K   +  L                S G+LAL +LAL    N E    
Sbjct: 67  QIQTLMQKMIQQIKYNVKSRL-------------SDVSSGELALIILALGVCRNAEENLI 113

Query: 119 VRGHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDS-VVD 177
              H  D+L ++ +  +E+ +      H G P T+YYQ  L +LALCL       + VV+
Sbjct: 114 YDYHLIDKLENKFQAEIENMEA-----HNGTPLTNYYQLSLDVLALCLFNGNYSTAEVVN 168

Query: 178 KLLYAVEPFHQGHH-SVDTAAMAGLAFTCLKRSNFN------PGRRQRITMAIRTVREEI 230
                 + ++ G   SVDT AMA LA TC+K+S  N       G  + I++  +++ E+I
Sbjct: 169 HFTPENKNYYFGSQFSVDTGAMAVLALTCVKKSLINGQIKADEGSLKNISIYTKSLVEKI 228

Query: 231 LKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMIS 290
           L  +   G  GN +ST  A+Q L  S     E    C +    +L  +  GAF N    +
Sbjct: 229 LSEKKENGLIGNTFSTGEAMQALFVSSDYYNENDWNCQQTLNTVLTEISQGAFSNPNAAA 288

Query: 291 QLLPVLNHKTYIDL-IFPDCLAPRVML-----EPAAETIPQTQEIISVTLQVLSLLPPYR 344
           Q+LP L  KT++D+     C++          EP   T P +Q  ISV   V  +   Y 
Sbjct: 289 QVLPALMGKTFLDINKDSSCVSASGNFNISADEPITVTPPDSQSYISVNYSV-RINETYF 347

Query: 345 QSISVLAGSTVEDVLKKAHELG----GFTYETQASLSGPYLTSVMGKAA--GEREFWQLL 398
            +++VL GS    V++KA ++     GFT E ++   GPY+T + G  A   +R +W+LL
Sbjct: 348 TNVTVLNGSVFLSVMEKAQKMNDTIFGFTMEERS--WGPYITCIQGLCANNNDRTYWELL 405

Query: 399 RDPNTPLLQGIADYRPKDGETIELR 423
                PL QG   Y  ++GE +E+R
Sbjct: 406 -SGGEPLSQGAGSYVVRNGENLEVR 429


>gi|32189398 gastric intrinsic factor (vitamin B synthesis)
           precursor [Homo sapiens]
          Length = 417

 Score =  102 bits (253), Expect = 9e-22
 Identities = 118/440 (26%), Positives = 188/440 (42%), Gaps = 62/440 (14%)

Query: 8   LFLLGVLGALT-------EMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRL 60
           L+LL +L A           C +P     LV   G  +L      S  + NPSI + + L
Sbjct: 6   LYLLSLLWATAGTSTQTQSSCSVPSAQEPLVN--GIQVLMENSVTSSAYPNPSILIAMNL 63

Query: 61  SSLQAGTKEDLYLHSLKLGYQQCLLGSAFSEDDGDCQGKPSMGQLALYLLALRANCEFVR 120
           +             +  L  Q+ L     S D+ D     ++GQL L ++AL ++C    
Sbjct: 64  AG------------AYNLKAQKLLTYQLMSSDNNDL----TIGQLGLTIMALTSSCRDP- 106

Query: 121 GHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDK-- 178
           G K   L  Q++ +      A          +++Y   L ILALC         +  +  
Sbjct: 107 GDKVSILQRQMENWAPSSPNAEA--------SAFYGPSLAILALCQKNSEATLPIAVRFA 158

Query: 179 --LLYAVEPFHQGHHSVDTAAMAGLAFTCLKRS---NFNPGRRQRITMAIRTVREEILKA 233
             LL    PF+     VDT AMA LA TC+          G R      ++ + E+I   
Sbjct: 159 KTLLANSSPFN-----VDTGAMATLALTCMYNKIPVGSEEGYRSLFGQVLKDIVEKISMK 213

Query: 234 QTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLL 293
               G  G++YST LA+Q L  +P   ++    C K    +L  ++ G F N + I+Q+L
Sbjct: 214 IKDNGIIGDIYSTGLAMQALSVTP-EPSKKEWNCKKTTDMILNEIKQGKFHNPMSIAQIL 272

Query: 294 PVLNHKTYIDLIFPDCLAPRVMLEPAAETIP----------QTQEIISVTLQVLSLLPPY 343
           P L  KTY+D+    C +P   ++P   + P               I+  L+ + LL   
Sbjct: 273 PSLKGKTYLDVPQVTC-SPDHEVQPTLPSNPGPGPTSASNITVIYTINNQLRGVELLFNE 331

Query: 344 RQSISVLAGSTVEDVLKKAHELGG-FTYETQASLSGPYLTSV--MGKAAGEREFWQLLRD 400
             ++SV +GS +  VL++A      F +ET  +  G  ++S+  + +    + +WQ L  
Sbjct: 332 TINVSVKSGSVLLVVLEEAQRKNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFLSG 391

Query: 401 PNTPLLQGIADYRPKDGETI 420
             TPL +G+ADY P + E I
Sbjct: 392 V-TPLNEGVADYIPFNHEHI 410


>gi|122937247 unc-13 homolog A [Homo sapiens]
          Length = 1791

 Score = 32.3 bits (72), Expect = 0.84
 Identities = 31/119 (26%), Positives = 44/119 (36%), Gaps = 13/119 (10%)

Query: 291  QLLPVLNHKTYIDLI-----FPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQ 345
            +LL  L++   IDL      FP     R  L+    T+     I    ++V  L  P R 
Sbjct: 1023 KLLDQLHNSLRIDLSMYRNNFPASSPER--LQDLKSTVDLLTSITFFRMKVQELQSPPRA 1080

Query: 346  S------ISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLL 398
            S      +     ST E +    HEL    Y+T  +  G  L    G +    +FW  L
Sbjct: 1081 SQVVKDCVKACLNSTYEYIFNNCHELYSREYQTDPAKKGEVLPEEQGPSIKNLDFWSKL 1139


>gi|14195616 protocadherin beta 9 precursor [Homo sapiens]
          Length = 797

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 312 PRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYE 371
           P ++L+ A +   + QE +S+TL  L    P R   S +    V DV   A +     YE
Sbjct: 192 PELVLDKALDR--EEQEELSLTLTALDGGSPSRSGTSTIR-IVVLDVNDNAPQFAQALYE 248

Query: 372 TQASLSGPYLTSVMGKAAGERE 393
           TQA  + P  + ++  +AG+ +
Sbjct: 249 TQAPENSPVGSLIVKVSAGDAD 270


>gi|15529996 son of sevenless homolog 1 [Homo sapiens]
          Length = 1333

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 24/126 (19%)

Query: 292 LLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISV---------TLQVLSLL-- 340
           LL ++ H T + L F  C+     LE     + +  EI+ V          L+V+S +  
Sbjct: 821 LLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNS 880

Query: 341 -PPYRQSISV-LAGSTVEDVLKKAHELGGFTYETQAS-----------LSGPYLTSVMGK 387
            P YR   +     S  + +L++AHEL    Y+   +             G YLT+++  
Sbjct: 881 SPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKT 940

Query: 388 AAGERE 393
             G  E
Sbjct: 941 EEGNPE 946


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 26/128 (20%), Positives = 53/128 (41%), Gaps = 3/128 (2%)

Query: 213 PGRRQRITMAIRTVREEILKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARV 272
           PG  +R  +    + E    A+T +    + +   + + F +   + GA + T  L+   
Sbjct: 231 PGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSR 290

Query: 273 ALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISV 332
           A+  +  + +F    +  QLL     +   DL+   C   R +    + +  Q +E+   
Sbjct: 291 AIRQAKDECSFH---IFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQE 347

Query: 333 TLQVLSLL 340
           TL+ L +L
Sbjct: 348 TLESLRVL 355


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,250,220
Number of Sequences: 37866
Number of extensions: 699933
Number of successful extensions: 1425
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1414
Number of HSP's gapped (non-prelim): 7
length of query: 427
length of database: 18,247,518
effective HSP length: 105
effective length of query: 322
effective length of database: 14,271,588
effective search space: 4595451336
effective search space used: 4595451336
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.