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Search of human proteins with 208609988
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|208609988 solute carrier family 25, member 44 isoform 2
[Homo sapiens]
(205 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|208609988 solute carrier family 25, member 44 isoform 2 [Homo... 416 e-117
gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo ... 292 2e-79
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 77 1e-14
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 75 4e-14
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 75 4e-14
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 75 4e-14
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 75 4e-14
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 75 4e-14
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 75 4e-14
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 74 9e-14
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 74 9e-14
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 74 9e-14
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 72 4e-13
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 72 4e-13
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 72 4e-13
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 71 7e-13
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 71 7e-13
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 69 4e-12
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 69 4e-12
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 66 2e-11
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 65 5e-11
gi|13994341 solute carrier family 25 member 2 [Homo sapiens] 64 7e-11
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 64 7e-11
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 64 9e-11
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 64 9e-11
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 64 1e-10
gi|115430257 solute carrier family 25, member 26 [Homo sapiens] 64 1e-10
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 64 1e-10
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 64 1e-10
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 63 2e-10
>gi|208609988 solute carrier family 25, member 44 isoform 2 [Homo
sapiens]
Length = 205
Score = 416 bits (1069), Expect = e-117
Identities = 205/205 (100%), Positives = 205/205 (100%)
Query: 1 MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA 60
MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA
Sbjct: 1 MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA 60
Query: 61 FIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSG 120
FIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSG
Sbjct: 61 FIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSG 120
Query: 121 PLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPST 180
PLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPST
Sbjct: 121 PLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPST 180
Query: 181 IVIVVGYESLKKLSLRPELVDSRHW 205
IVIVVGYESLKKLSLRPELVDSRHW
Sbjct: 181 IVIVVGYESLKKLSLRPELVDSRHW 205
>gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo
sapiens]
Length = 314
Score = 292 bits (747), Expect = 2e-79
Identities = 145/157 (92%), Positives = 148/157 (94%)
Query: 49 KGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPK 108
+G + T D +ILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPK
Sbjct: 158 QGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPK 217
Query: 109 ECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKG 168
ECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKG
Sbjct: 218 ECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKG 277
Query: 169 LSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW 205
LSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW
Sbjct: 278 LSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW 314
Score = 166 bits (420), Expect = 1e-41
Identities = 94/203 (46%), Positives = 121/203 (59%), Gaps = 25/203 (12%)
Query: 1 MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA 60
MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA
Sbjct: 1 MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA 60
Query: 61 FIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSG 120
FIKIL+ADG+ G YRG++ + T I + Y ++ + V V+G
Sbjct: 61 FIKILRADGITGLYRGFLVNTFTLISGQC----YVTTYELTRKFVADYSQSNTVKSLVAG 116
Query: 121 PLAAATASILTNPMDVIRTRVQVEGKNSIILTF---------------------RQLMAE 159
A+ A +T P+DV+ + ++ K + F RQ++
Sbjct: 117 GSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQA 176
Query: 160 EGPWGLMKGLSARIISATPSTIV 182
+G G +G A +++ P++ V
Sbjct: 177 DGLRGFYRGYVASLLTYIPNSAV 199
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 77.0 bits (188), Expect = 1e-14
Identities = 51/190 (26%), Positives = 101/190 (53%), Gaps = 13/190 (6%)
Query: 13 EHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRG 72
E L ++ +V G + +YP +++TRL +++ Y G D +IL+ +G R
Sbjct: 275 ETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRR-TGQYKGLLDCARRILEREGPRA 333
Query: 73 FYRGYVASLLTYIP----NSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATAS 128
FYRGY+ ++L IP + AV+ +++ +Q S+ P I+ G +++
Sbjct: 334 FYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSH--DSADPGILVLLACGTISSTCGQ 391
Query: 129 ILTNPMDVIRTRVQ----VEG--KNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIV 182
I + P+ ++RTR+Q +EG + S++ R ++++EG GL +G++ + P+ +
Sbjct: 392 IASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSI 451
Query: 183 IVVGYESLKK 192
V YE++K+
Sbjct: 452 SYVVYENMKQ 461
Score = 58.9 bits (141), Expect = 3e-09
Identities = 47/189 (24%), Positives = 84/189 (44%), Gaps = 9/189 (4%)
Query: 19 KFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYV 78
K V G + R P ++ +QV K+ ++ G+R +RG
Sbjct: 187 KQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNG 246
Query: 79 ASLLTYIPNSAVWWPFYHFYAEQL--SYLCPKECPHIVFQAVSGPLAAATASILTNPMDV 136
++L P SA+ + Y EQ+ + L +E H+ + V+G LA ATA + PM+V
Sbjct: 247 INVLKIAPESAIKFMAY----EQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEV 302
Query: 137 IRTRVQVEGK---NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKL 193
++TR+ + ++ R+++ EGP +G ++ P + + YE+LK
Sbjct: 303 LKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNW 362
Query: 194 SLRPELVDS 202
L+ DS
Sbjct: 363 WLQQYSHDS 371
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 75.1 bits (183), Expect = 4e-14
Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 34 SVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWP 93
S+YP +++TR+ ++K Y G D +IL +G+ FY+GYV ++L IP + +
Sbjct: 297 SIYPMEVLKTRMALRK-TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 355
Query: 94 FYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ----VEGKN 147
Y A Y P + G +++ + + P+ ++RTR+Q +EG
Sbjct: 356 VYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAP 415
Query: 148 SIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 191
+ ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 416 EVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 59.7 bits (143), Expect = 2e-09
Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 15/196 (7%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLR 71
W HL V G + R P ++ +QV +S G F ++++ G R
Sbjct: 187 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
Query: 72 GFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYL--CPKECPHIVFQAVSGPLAAATASI 129
+RG ++L P SA+ + Y EQ+ L +E I + V+G LA A A
Sbjct: 241 SLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVAGSLAGAIAQS 296
Query: 130 LTNPMDVIRTRVQVE--GKNSIIL-TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVG 186
PM+V++TR+ + G+ S +L R+++A EG KG ++ P + +
Sbjct: 297 SIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 356
Query: 187 YESLKKLSLRPELVDS 202
YE+LK L+ V+S
Sbjct: 357 YETLKNAWLQHYAVNS 372
Score = 35.0 bits (79), Expect = 0.045
Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 32 RVSVYPFTLIRTRLQVQKG-KSLYHGTFDAFIK-ILQADGLRGFYRGYVASLLTYIPNSA 89
+++ YP L+RTR+Q Q + T + K IL+ +G G YRG + + IP +
Sbjct: 392 QLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVS 451
Query: 90 VWWPFY 95
+ + Y
Sbjct: 452 ISYVVY 457
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 75.1 bits (183), Expect = 4e-14
Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 34 SVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWP 93
S+YP +++TR+ ++K Y G D +IL +G+ FY+GYV ++L IP + +
Sbjct: 331 SIYPMEVLKTRMALRK-TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 389
Query: 94 FYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ----VEGKN 147
Y A Y P + G +++ + + P+ ++RTR+Q +EG
Sbjct: 390 VYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAP 449
Query: 148 SIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 191
+ ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 450 EVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 59.7 bits (143), Expect = 2e-09
Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 15/196 (7%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLR 71
W HL V G + R P ++ +QV +S G F ++++ G R
Sbjct: 221 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 274
Query: 72 GFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYL--CPKECPHIVFQAVSGPLAAATASI 129
+RG ++L P SA+ + Y EQ+ L +E I + V+G LA A A
Sbjct: 275 SLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVAGSLAGAIAQS 330
Query: 130 LTNPMDVIRTRVQVE--GKNSIIL-TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVG 186
PM+V++TR+ + G+ S +L R+++A EG KG ++ P + +
Sbjct: 331 SIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 390
Query: 187 YESLKKLSLRPELVDS 202
YE+LK L+ V+S
Sbjct: 391 YETLKNAWLQHYAVNS 406
Score = 35.0 bits (79), Expect = 0.045
Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 32 RVSVYPFTLIRTRLQVQKG-KSLYHGTFDAFIK-ILQADGLRGFYRGYVASLLTYIPNSA 89
+++ YP L+RTR+Q Q + T + K IL+ +G G YRG + + IP +
Sbjct: 426 QLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVS 485
Query: 90 VWWPFY 95
+ + Y
Sbjct: 486 ISYVVY 491
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 75.1 bits (183), Expect = 4e-14
Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 34 SVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWP 93
S+YP +++TR+ ++K Y G D +IL +G+ FY+GYV ++L IP + +
Sbjct: 317 SIYPMEVLKTRMALRK-TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 375
Query: 94 FYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ----VEGKN 147
Y A Y P + G +++ + + P+ ++RTR+Q +EG
Sbjct: 376 VYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAP 435
Query: 148 SIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 191
+ ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 436 EVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481
Score = 59.7 bits (143), Expect = 2e-09
Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 15/196 (7%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLR 71
W HL V G + R P ++ +QV +S G F ++++ G R
Sbjct: 207 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 260
Query: 72 GFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYL--CPKECPHIVFQAVSGPLAAATASI 129
+RG ++L P SA+ + Y EQ+ L +E I + V+G LA A A
Sbjct: 261 SLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVAGSLAGAIAQS 316
Query: 130 LTNPMDVIRTRVQVE--GKNSIIL-TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVG 186
PM+V++TR+ + G+ S +L R+++A EG KG ++ P + +
Sbjct: 317 SIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 376
Query: 187 YESLKKLSLRPELVDS 202
YE+LK L+ V+S
Sbjct: 377 YETLKNAWLQHYAVNS 392
Score = 35.0 bits (79), Expect = 0.045
Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 32 RVSVYPFTLIRTRLQVQKG-KSLYHGTFDAFIK-ILQADGLRGFYRGYVASLLTYIPNSA 89
+++ YP L+RTR+Q Q + T + K IL+ +G G YRG + + IP +
Sbjct: 412 QLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVS 471
Query: 90 VWWPFY 95
+ + Y
Sbjct: 472 ISYVVY 477
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 75.1 bits (183), Expect = 4e-14
Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 34 SVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWP 93
S+YP +++TR+ ++K Y G D +IL +G+ FY+GYV ++L IP + +
Sbjct: 297 SIYPMEVLKTRMALRK-TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 355
Query: 94 FYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ----VEGKN 147
Y A Y P + G +++ + + P+ ++RTR+Q +EG
Sbjct: 356 VYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAP 415
Query: 148 SIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 191
+ ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 416 EVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 59.7 bits (143), Expect = 2e-09
Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 15/196 (7%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLR 71
W HL V G + R P ++ +QV +S G F ++++ G R
Sbjct: 187 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
Query: 72 GFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYL--CPKECPHIVFQAVSGPLAAATASI 129
+RG ++L P SA+ + Y EQ+ L +E I + V+G LA A A
Sbjct: 241 SLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVAGSLAGAIAQS 296
Query: 130 LTNPMDVIRTRVQVE--GKNSIIL-TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVG 186
PM+V++TR+ + G+ S +L R+++A EG KG ++ P + +
Sbjct: 297 SIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 356
Query: 187 YESLKKLSLRPELVDS 202
YE+LK L+ V+S
Sbjct: 357 YETLKNAWLQHYAVNS 372
Score = 35.0 bits (79), Expect = 0.045
Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 32 RVSVYPFTLIRTRLQVQKG-KSLYHGTFDAFIK-ILQADGLRGFYRGYVASLLTYIPNSA 89
+++ YP L+RTR+Q Q + T + K IL+ +G G YRG + + IP +
Sbjct: 392 QLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVS 451
Query: 90 VWWPFY 95
+ + Y
Sbjct: 452 ISYVVY 457
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 75.1 bits (183), Expect = 4e-14
Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 34 SVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWP 93
S+YP +++TR+ ++K Y G D +IL +G+ FY+GYV ++L IP + +
Sbjct: 194 SIYPMEVLKTRMALRK-TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 252
Query: 94 FYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ----VEGKN 147
Y A Y P + G +++ + + P+ ++RTR+Q +EG
Sbjct: 253 VYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAP 312
Query: 148 SIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 191
+ ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 313 EVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358
Score = 59.7 bits (143), Expect = 2e-09
Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 15/196 (7%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLR 71
W HL V G + R P ++ +QV +S G F ++++ G R
Sbjct: 84 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 137
Query: 72 GFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYL--CPKECPHIVFQAVSGPLAAATASI 129
+RG ++L P SA+ + Y EQ+ L +E I + V+G LA A A
Sbjct: 138 SLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVAGSLAGAIAQS 193
Query: 130 LTNPMDVIRTRVQVE--GKNSIIL-TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVG 186
PM+V++TR+ + G+ S +L R+++A EG KG ++ P + +
Sbjct: 194 SIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 253
Query: 187 YESLKKLSLRPELVDS 202
YE+LK L+ V+S
Sbjct: 254 YETLKNAWLQHYAVNS 269
Score = 35.0 bits (79), Expect = 0.045
Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 32 RVSVYPFTLIRTRLQVQKG-KSLYHGTFDAFIK-ILQADGLRGFYRGYVASLLTYIPNSA 89
+++ YP L+RTR+Q Q + T + K IL+ +G G YRG + + IP +
Sbjct: 289 QLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVS 348
Query: 90 VWWPFY 95
+ + Y
Sbjct: 349 ISYVVY 354
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 75.1 bits (183), Expect = 4e-14
Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 9/166 (5%)
Query: 34 SVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWP 93
S+YP +++TR+ ++K Y G D +IL +G+ FY+GYV ++L IP + +
Sbjct: 331 SIYPMEVLKTRMALRK-TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLA 389
Query: 94 FYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ----VEGKN 147
Y A Y P + G +++ + + P+ ++RTR+Q +EG
Sbjct: 390 VYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAP 449
Query: 148 SIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 191
+ ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 450 EVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 59.7 bits (143), Expect = 2e-09
Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 15/196 (7%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLR 71
W HL V G + R P ++ +QV +S G F ++++ G R
Sbjct: 221 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 274
Query: 72 GFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYL--CPKECPHIVFQAVSGPLAAATASI 129
+RG ++L P SA+ + Y EQ+ L +E I + V+G LA A A
Sbjct: 275 SLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVAGSLAGAIAQS 330
Query: 130 LTNPMDVIRTRVQVE--GKNSIIL-TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVG 186
PM+V++TR+ + G+ S +L R+++A EG KG ++ P + +
Sbjct: 331 SIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 390
Query: 187 YESLKKLSLRPELVDS 202
YE+LK L+ V+S
Sbjct: 391 YETLKNAWLQHYAVNS 406
Score = 35.0 bits (79), Expect = 0.045
Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 32 RVSVYPFTLIRTRLQVQKG-KSLYHGTFDAFIK-ILQADGLRGFYRGYVASLLTYIPNSA 89
+++ YP L+RTR+Q Q + T + K IL+ +G G YRG + + IP +
Sbjct: 426 QLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVS 485
Query: 90 VWWPFY 95
+ + Y
Sbjct: 486 ISYVVY 491
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 73.9 bits (180), Expect = 9e-14
Identities = 51/164 (31%), Positives = 84/164 (51%), Gaps = 14/164 (8%)
Query: 37 PFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYH 96
P +++ RLQV + G + + +L+ G+ G Y+G A L IP SA+++P Y
Sbjct: 446 PLEIVKIRLQV--AGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVY- 502
Query: 97 FYAEQLSYLCPKECPHI--VFQAVSGPLAAATASILTNPMDVIRTRVQVEGK------NS 148
L E H+ + +G +A A+ L P DVI+TR+QV + +
Sbjct: 503 ---AHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSG 559
Query: 149 IILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 192
+I FR+++ EEGP KG +AR+ ++P V +V YE L++
Sbjct: 560 VIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
Score = 68.6 bits (166), Expect = 4e-12
Identities = 44/168 (26%), Positives = 81/168 (48%), Gaps = 10/168 (5%)
Query: 34 SVYPFTLIRTRLQVQKGKS------LYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPN 87
+VYP L++TR+Q Q+G +Y +FD F K+L+ +G G YRG + L+ P
Sbjct: 343 AVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPE 402
Query: 88 SAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK- 146
A+ F ++ + + + ++G A + I TNP+++++ R+QV G+
Sbjct: 403 KAIKLTVNDFVRDK--FTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEI 460
Query: 147 -NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKL 193
++ ++ + G +GL KG A + P + + Y K L
Sbjct: 461 TTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLL 508
Score = 33.5 bits (75), Expect = 0.13
Identities = 19/73 (26%), Positives = 38/73 (52%), Gaps = 10/73 (13%)
Query: 120 GPLAAATASILTNPMDVIRTRVQVE-GKNSII---------LTFRQLMAEEGPWGLMKGL 169
G +A A + P+D+++TR+Q + G S++ F++++ EG +GL +GL
Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
Query: 170 SARIISATPSTIV 182
++I P +
Sbjct: 393 IPQLIGVAPEKAI 405
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 73.9 bits (180), Expect = 9e-14
Identities = 46/166 (27%), Positives = 87/166 (52%), Gaps = 9/166 (5%)
Query: 35 VYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPF 94
+YP +++TRL V K Y G +D KIL+ +GL FY+GYV +LL IP + +
Sbjct: 306 IYPMEVMKTRLAVGK-TGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAV 364
Query: 95 YHFYAEQLSYLCPKEC--PHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEG------K 146
Y K+ P ++ G L++ + + P+ ++RTR+Q + +
Sbjct: 365 YELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQ 424
Query: 147 NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 192
+++ FR+++++EG GL +G++ + P+ + V YE++K+
Sbjct: 425 LNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470
Score = 56.2 bits (134), Expect = 2e-08
Identities = 47/167 (28%), Positives = 79/167 (47%), Gaps = 13/167 (7%)
Query: 32 RVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAV- 90
R S P ++ +QV KS F F ++++ G+R +RG +++ P +AV
Sbjct: 209 RTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVK 268
Query: 91 WWPFYHFYAEQLSYLCPKECPHI-VFQA-VSGPLAAATASILTNPMDVIRTRVQVEGK-- 146
+W + EQ L +E I F+ +SG +A ATA PM+V++TR+ V GK
Sbjct: 269 FWAY-----EQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV-GKTG 322
Query: 147 --NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 191
+ I ++++ EG KG ++ P + + YE LK
Sbjct: 323 QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLK 369
Score = 45.1 bits (105), Expect = 4e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 116 QAVSGPLAAATASILTNPMDVIRTRVQVEGKNS----IILTFRQLMAEEGPWGLMKGLSA 171
Q ++G +A A + T P+D ++ +QV G S I FRQ++ E G L +G
Sbjct: 197 QLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGT 256
Query: 172 RIISATPSTIVIVVGYESLKKL 193
+I P T V YE KKL
Sbjct: 257 NVIKIAPETAVKFWAYEQYKKL 278
Score = 34.3 bits (77), Expect = 0.076
Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 8/69 (11%)
Query: 32 RVSVYPFTLIRTRLQVQKGKSLYHGT-----FDAFIKILQADGLRGFYRGYVASLLTYIP 86
+++ YP L+RTR+Q Q ++ G+ F +I+ +G+ G YRG + + +P
Sbjct: 400 QLASYPLALVRTRMQAQ---AMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLP 456
Query: 87 NSAVWWPFY 95
+ + Y
Sbjct: 457 AVGISYVVY 465
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 73.9 bits (180), Expect = 9e-14
Identities = 46/166 (27%), Positives = 87/166 (52%), Gaps = 9/166 (5%)
Query: 35 VYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPF 94
+YP +++TRL V K Y G +D KIL+ +GL FY+GYV +LL IP + +
Sbjct: 287 IYPMEVMKTRLAVGK-TGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAV 345
Query: 95 YHFYAEQLSYLCPKEC--PHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEG------K 146
Y K+ P ++ G L++ + + P+ ++RTR+Q + +
Sbjct: 346 YELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQ 405
Query: 147 NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 192
+++ FR+++++EG GL +G++ + P+ + V YE++K+
Sbjct: 406 LNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
Score = 56.2 bits (134), Expect = 2e-08
Identities = 47/167 (28%), Positives = 79/167 (47%), Gaps = 13/167 (7%)
Query: 32 RVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAV- 90
R S P ++ +QV KS F F ++++ G+R +RG +++ P +AV
Sbjct: 190 RTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVK 249
Query: 91 WWPFYHFYAEQLSYLCPKECPHI-VFQA-VSGPLAAATASILTNPMDVIRTRVQVEGK-- 146
+W + EQ L +E I F+ +SG +A ATA PM+V++TR+ V GK
Sbjct: 250 FWAY-----EQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV-GKTG 303
Query: 147 --NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 191
+ I ++++ EG KG ++ P + + YE LK
Sbjct: 304 QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLK 350
Score = 45.1 bits (105), Expect = 4e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 116 QAVSGPLAAATASILTNPMDVIRTRVQVEGKNS----IILTFRQLMAEEGPWGLMKGLSA 171
Q ++G +A A + T P+D ++ +QV G S I FRQ++ E G L +G
Sbjct: 178 QLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGT 237
Query: 172 RIISATPSTIVIVVGYESLKKL 193
+I P T V YE KKL
Sbjct: 238 NVIKIAPETAVKFWAYEQYKKL 259
Score = 34.3 bits (77), Expect = 0.076
Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 8/69 (11%)
Query: 32 RVSVYPFTLIRTRLQVQKGKSLYHGT-----FDAFIKILQADGLRGFYRGYVASLLTYIP 86
+++ YP L+RTR+Q Q ++ G+ F +I+ +G+ G YRG + + +P
Sbjct: 381 QLASYPLALVRTRMQAQ---AMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLP 437
Query: 87 NSAVWWPFY 95
+ + Y
Sbjct: 438 AVGISYVVY 446
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 71.6 bits (174), Expect = 4e-13
Identities = 52/183 (28%), Positives = 84/183 (45%), Gaps = 11/183 (6%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGK-------SLYHGTFDAFIKILQADGLRGFY 74
V G ++ R + PF +I+ R Q+Q + + YHG A +ILQ +G F+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 75 RGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPM 134
+G+V + + I AV + + E + + V G LAA A++ +P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 135 DVIRTRVQVEGKNSIILTFRQ----LMAEEGPWGLMKGLSARIISATPSTIVIVVGYESL 190
DV+RTR +G+ + T R + EGP KGL+ +I+ P + Y SL
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 191 KKL 193
K L
Sbjct: 200 KHL 202
Score = 58.2 bits (139), Expect = 5e-09
Identities = 44/183 (24%), Positives = 78/183 (42%), Gaps = 15/183 (8%)
Query: 21 YVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVAS 80
+V G M ++V+P ++RTR Q +Y+ A + +++G + FY+G +
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181
Query: 81 LLTYIPNSAVWWPFYHFYAEQLSYLCPKECP--HIVFQAVSGPLAAATASILTNPMDVIR 138
L+ P + + + Y + P E + + G A + LT P+D+ +
Sbjct: 182 LIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFK 241
Query: 139 TRVQVEGKNSIILTF-------------RQLMAEEGPWGLMKGLSARIISATPSTIVIVV 185
R+QV G F +Q++ +EG G KGLS ++ A ST +
Sbjct: 242 KRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFF 301
Query: 186 GYE 188
YE
Sbjct: 302 SYE 304
Score = 38.5 bits (88), Expect = 0.004
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 13/101 (12%)
Query: 117 AVSGPLAAATASILTNPMDVIRTRVQVEGK-----------NSIILTFRQLMAEEGPWGL 165
AV+G ++ L +P DVI+ R Q++ + + I+ RQ++ EEGP
Sbjct: 19 AVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAF 78
Query: 166 MKG-LSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW 205
KG + A+I+S + + +E L +L R + D+R +
Sbjct: 79 WKGHVPAQILSIGYGAVQF-LSFEMLTELVHRGSVYDAREF 118
Score = 32.7 bits (73), Expect = 0.22
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 9/84 (10%)
Query: 24 GVAMTMMIRVSVYPFTLIRTRLQVQKGKSL---------YHGTFDAFIKILQADGLRGFY 74
G ++ + YP L + RLQV + Y G D ++LQ +G GF+
Sbjct: 223 GSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFF 282
Query: 75 RGYVASLLTYIPNSAVWWPFYHFY 98
+G SLL ++ + Y F+
Sbjct: 283 KGLSPSLLKAALSTGFMFFSYEFF 306
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 71.6 bits (174), Expect = 4e-13
Identities = 52/183 (28%), Positives = 84/183 (45%), Gaps = 11/183 (6%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGK-------SLYHGTFDAFIKILQADGLRGFY 74
V G ++ R + PF +I+ R Q+Q + + YHG A +ILQ +G F+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 75 RGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPM 134
+G+V + + I AV + + E + + V G LAA A++ +P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 135 DVIRTRVQVEGKNSIILTFRQ----LMAEEGPWGLMKGLSARIISATPSTIVIVVGYESL 190
DV+RTR +G+ + T R + EGP KGL+ +I+ P + Y SL
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 191 KKL 193
K L
Sbjct: 200 KHL 202
Score = 58.2 bits (139), Expect = 5e-09
Identities = 44/183 (24%), Positives = 78/183 (42%), Gaps = 15/183 (8%)
Query: 21 YVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVAS 80
+V G M ++V+P ++RTR Q +Y+ A + +++G + FY+G +
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181
Query: 81 LLTYIPNSAVWWPFYHFYAEQLSYLCPKECP--HIVFQAVSGPLAAATASILTNPMDVIR 138
L+ P + + + Y + P E + + G A + LT P+D+ +
Sbjct: 182 LIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFK 241
Query: 139 TRVQVEGKNSIILTF-------------RQLMAEEGPWGLMKGLSARIISATPSTIVIVV 185
R+QV G F +Q++ +EG G KGLS ++ A ST +
Sbjct: 242 KRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFF 301
Query: 186 GYE 188
YE
Sbjct: 302 SYE 304
Score = 38.5 bits (88), Expect = 0.004
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 13/101 (12%)
Query: 117 AVSGPLAAATASILTNPMDVIRTRVQVEGK-----------NSIILTFRQLMAEEGPWGL 165
AV+G ++ L +P DVI+ R Q++ + + I+ RQ++ EEGP
Sbjct: 19 AVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAF 78
Query: 166 MKG-LSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW 205
KG + A+I+S + + +E L +L R + D+R +
Sbjct: 79 WKGHVPAQILSIGYGAVQF-LSFEMLTELVHRGSVYDAREF 118
Score = 32.7 bits (73), Expect = 0.22
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 9/84 (10%)
Query: 24 GVAMTMMIRVSVYPFTLIRTRLQVQKGKSL---------YHGTFDAFIKILQADGLRGFY 74
G ++ + YP L + RLQV + Y G D ++LQ +G GF+
Sbjct: 223 GSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFF 282
Query: 75 RGYVASLLTYIPNSAVWWPFYHFY 98
+G SLL ++ + Y F+
Sbjct: 283 KGLSPSLLKAALSTGFMFFSYEFF 306
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 71.6 bits (174), Expect = 4e-13
Identities = 52/183 (28%), Positives = 84/183 (45%), Gaps = 11/183 (6%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGK-------SLYHGTFDAFIKILQADGLRGFY 74
V G ++ R + PF +I+ R Q+Q + + YHG A +ILQ +G F+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 75 RGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPM 134
+G+V + + I AV + + E + + V G LAA A++ +P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 135 DVIRTRVQVEGKNSIILTFRQ----LMAEEGPWGLMKGLSARIISATPSTIVIVVGYESL 190
DV+RTR +G+ + T R + EGP KGL+ +I+ P + Y SL
Sbjct: 140 DVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL 199
Query: 191 KKL 193
K L
Sbjct: 200 KHL 202
Score = 58.2 bits (139), Expect = 5e-09
Identities = 44/183 (24%), Positives = 78/183 (42%), Gaps = 15/183 (8%)
Query: 21 YVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVAS 80
+V G M ++V+P ++RTR Q +Y+ A + +++G + FY+G +
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181
Query: 81 LLTYIPNSAVWWPFYHFYAEQLSYLCPKECP--HIVFQAVSGPLAAATASILTNPMDVIR 138
L+ P + + + Y + P E + + G A + LT P+D+ +
Sbjct: 182 LIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFK 241
Query: 139 TRVQVEGKNSIILTF-------------RQLMAEEGPWGLMKGLSARIISATPSTIVIVV 185
R+QV G F +Q++ +EG G KGLS ++ A ST +
Sbjct: 242 KRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFF 301
Query: 186 GYE 188
YE
Sbjct: 302 SYE 304
Score = 38.5 bits (88), Expect = 0.004
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 13/101 (12%)
Query: 117 AVSGPLAAATASILTNPMDVIRTRVQVEGK-----------NSIILTFRQLMAEEGPWGL 165
AV+G ++ L +P DVI+ R Q++ + + I+ RQ++ EEGP
Sbjct: 19 AVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAF 78
Query: 166 MKG-LSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW 205
KG + A+I+S + + +E L +L R + D+R +
Sbjct: 79 WKGHVPAQILSIGYGAVQF-LSFEMLTELVHRGSVYDAREF 118
Score = 32.7 bits (73), Expect = 0.22
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 9/84 (10%)
Query: 24 GVAMTMMIRVSVYPFTLIRTRLQVQKGKSL---------YHGTFDAFIKILQADGLRGFY 74
G ++ + YP L + RLQV + Y G D ++LQ +G GF+
Sbjct: 223 GSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFF 282
Query: 75 RGYVASLLTYIPNSAVWWPFYHFY 98
+G SLL ++ + Y F+
Sbjct: 283 KGLSPSLLKAALSTGFMFFSYEFF 306
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 70.9 bits (172), Expect = 7e-13
Identities = 49/162 (30%), Positives = 82/162 (50%), Gaps = 10/162 (6%)
Query: 37 PFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYH 96
P +++ RLQV + G + + +++ G G Y+G A L IP SA+++P Y
Sbjct: 448 PLEIVKIRLQV--AGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYA 505
Query: 97 FYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK------NSII 150
+ + P + A G +A A+ L P DVI+TR+QV + + +I
Sbjct: 506 HVKASFANEDGQVSPGSLLLA--GAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVI 563
Query: 151 LTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 192
FR+++ EEGP L KG AR+ ++P V ++ YE L++
Sbjct: 564 DCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 605
Score = 68.6 bits (166), Expect = 4e-12
Identities = 43/166 (25%), Positives = 83/166 (50%), Gaps = 10/166 (6%)
Query: 34 SVYPFTLIRTRLQVQK------GKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPN 87
+VYP L++TR+Q Q+ G+ +Y +FD F K+L+ +G G YRG + LL P
Sbjct: 345 AVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPE 404
Query: 88 SAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK- 146
A+ F ++ ++ + + ++G A + I TNP+++++ R+QV G+
Sbjct: 405 KAIKLTVNDFVRDK--FMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEI 462
Query: 147 -NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 191
++ ++ + G +G+ KG A + P + + Y +K
Sbjct: 463 TTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVK 508
Score = 31.2 bits (69), Expect = 0.64
Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 12/74 (16%)
Query: 120 GPLAAATASILTNPMDVIRTRVQVEG-----------KNSIILTFRQLMAEEGPWGLMKG 168
G +A A + P+D+++TR+Q + KNS F++++ EG +GL +G
Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFD-CFKKVLRYEGFFGLYRG 393
Query: 169 LSARIISATPSTIV 182
L +++ P +
Sbjct: 394 LLPQLLGVAPEKAI 407
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 70.9 bits (172), Expect = 7e-13
Identities = 49/162 (30%), Positives = 82/162 (50%), Gaps = 10/162 (6%)
Query: 37 PFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYH 96
P +++ RLQV + G + + +++ G G Y+G A L IP SA+++P Y
Sbjct: 449 PLEIVKIRLQV--AGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYA 506
Query: 97 FYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK------NSII 150
+ + P + A G +A A+ L P DVI+TR+QV + + +I
Sbjct: 507 HVKASFANEDGQVSPGSLLLA--GAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVI 564
Query: 151 LTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 192
FR+++ EEGP L KG AR+ ++P V ++ YE L++
Sbjct: 565 DCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 606
Score = 68.6 bits (166), Expect = 4e-12
Identities = 43/166 (25%), Positives = 83/166 (50%), Gaps = 10/166 (6%)
Query: 34 SVYPFTLIRTRLQVQK------GKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPN 87
+VYP L++TR+Q Q+ G+ +Y +FD F K+L+ +G G YRG + LL P
Sbjct: 346 AVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPE 405
Query: 88 SAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK- 146
A+ F ++ ++ + + ++G A + I TNP+++++ R+QV G+
Sbjct: 406 KAIKLTVNDFVRDK--FMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEI 463
Query: 147 -NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 191
++ ++ + G +G+ KG A + P + + Y +K
Sbjct: 464 TTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVK 509
Score = 31.2 bits (69), Expect = 0.64
Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 12/74 (16%)
Query: 120 GPLAAATASILTNPMDVIRTRVQVEG-----------KNSIILTFRQLMAEEGPWGLMKG 168
G +A A + P+D+++TR+Q + KNS F++++ EG +GL +G
Sbjct: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFD-CFKKVLRYEGFFGLYRG 394
Query: 169 LSARIISATPSTIV 182
L +++ P +
Sbjct: 395 LLPQLLGVAPEKAI 408
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 68.6 bits (166), Expect = 4e-12
Identities = 49/167 (29%), Positives = 79/167 (47%), Gaps = 16/167 (9%)
Query: 35 VYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADG-LRGFYRGYVASLLTYIPNSAVWWP 93
+ P L+RT+LQ Q + + A ++ A G R + G+ + L +P SA++W
Sbjct: 171 ISPLELMRTKLQAQH---VSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWF 227
Query: 94 FYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVE--------- 144
Y L+ PK+ + V+G ++ A++LT P DV++T+ QV
Sbjct: 228 NYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRV 287
Query: 145 ---GKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYE 188
+S L R++ AE G GL G RII A PS +++ YE
Sbjct: 288 NPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 334
Score = 50.1 bits (118), Expect = 1e-06
Identities = 34/141 (24%), Positives = 70/141 (49%), Gaps = 6/141 (4%)
Query: 54 YHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHI 113
+ GT DAF+KI++ +G R + G A+L+ +P +A+ ++ Y + ++LC +
Sbjct: 96 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAI---YFTAYDQLKAFLCGRALTSD 152
Query: 114 VF-QAVSGPLAAATASILTNPMDVIRTRVQVE--GKNSIILTFRQLMAEEGPWGLMKGLS 170
++ V+G LA + +P++++RT++Q + + R +A+ G L G
Sbjct: 153 LYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWG 212
Query: 171 ARIISATPSTIVIVVGYESLK 191
+ P + + YE +K
Sbjct: 213 PTALRDVPFSALYWFNYELVK 233
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 68.6 bits (166), Expect = 4e-12
Identities = 49/167 (29%), Positives = 79/167 (47%), Gaps = 16/167 (9%)
Query: 35 VYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADG-LRGFYRGYVASLLTYIPNSAVWWP 93
+ P L+RT+LQ Q + + A ++ A G R + G+ + L +P SA++W
Sbjct: 179 ISPLELMRTKLQAQH---VSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWF 235
Query: 94 FYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVE--------- 144
Y L+ PK+ + V+G ++ A++LT P DV++T+ QV
Sbjct: 236 NYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRV 295
Query: 145 ---GKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYE 188
+S L R++ AE G GL G RII A PS +++ YE
Sbjct: 296 NPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
Score = 50.1 bits (118), Expect = 1e-06
Identities = 34/141 (24%), Positives = 70/141 (49%), Gaps = 6/141 (4%)
Query: 54 YHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHI 113
+ GT DAF+KI++ +G R + G A+L+ +P +A+ ++ Y + ++LC +
Sbjct: 104 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAI---YFTAYDQLKAFLCGRALTSD 160
Query: 114 VF-QAVSGPLAAATASILTNPMDVIRTRVQVE--GKNSIILTFRQLMAEEGPWGLMKGLS 170
++ V+G LA + +P++++RT++Q + + R +A+ G L G
Sbjct: 161 LYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWG 220
Query: 171 ARIISATPSTIVIVVGYESLK 191
+ P + + YE +K
Sbjct: 221 PTALRDVPFSALYWFNYELVK 241
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 66.2 bits (160), Expect = 2e-11
Identities = 52/190 (27%), Positives = 87/190 (45%), Gaps = 19/190 (10%)
Query: 16 DKKKFYVFGVAMTMMIRVSVY-PFTLIRTRLQVQ---KGKSLYHGTFDAFIKILQADGLR 71
D + ++ AM ++ P LI+TRLQ+ +G+ G F+ K+ Q DGL+
Sbjct: 116 DSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRM-GAFECVRKVYQTDGLK 174
Query: 72 GFYRGYVASLLTYIPNSAVWWPFYHFYAEQL-----------SYLCPKECPHIVFQAVSG 120
GFYRG AS I + + + Y ++L KE V ++
Sbjct: 175 GFYRGMSAS-YAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAA 233
Query: 121 PLAAATASILTNPMDVIRTRVQVEGK--NSIILTFRQLMAEEGPWGLMKGLSARIISATP 178
+ A+ + P +V+RTR++ EG S T L+ EEG L +GL+ ++ P
Sbjct: 234 ATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIP 293
Query: 179 STIVIVVGYE 188
+T +++ YE
Sbjct: 294 NTAIMMATYE 303
Score = 33.1 bits (74), Expect = 0.17
Identities = 20/96 (20%), Positives = 37/96 (38%), Gaps = 22/96 (22%)
Query: 119 SGPLAAATASILTNPMDVIRTRVQVEGKNSIILT----------------------FRQL 156
+G +ILT P++V++TR+Q I + +
Sbjct: 12 AGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVI 71
Query: 157 MAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 192
+ +EGP L +GL ++ PS + Y + K+
Sbjct: 72 LEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKE 107
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 64.7 bits (156), Expect = 5e-11
Identities = 46/157 (29%), Positives = 77/157 (49%), Gaps = 11/157 (7%)
Query: 44 RLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFY----HFYA 99
++Q G+S Y GT D K+ Q G+RG Y+G V +L+ +P S +++ Y + +
Sbjct: 139 QIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFT 198
Query: 100 EQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQV--EGK--NSIILTFRQ 155
+ + P I+ V+G +A + P DV+++R Q GK N R+
Sbjct: 199 PEGKRVSELSAPRIL---VAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRE 255
Query: 156 LMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 192
L+ +EG L KG +A +I A P+ +G+E K
Sbjct: 256 LIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMK 292
Score = 50.8 bits (120), Expect = 8e-07
Identities = 43/169 (25%), Positives = 77/169 (45%), Gaps = 12/169 (7%)
Query: 36 YPFTLIRTRLQVQKGK-----SLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAV 90
+P ++ RLQ Q +Y GTFD F K L +G+ G YRG A ++ P AV
Sbjct: 29 HPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAV 88
Query: 91 WWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVE---GKN 147
+ F ++L P++ +G L+ + + P + I+ +Q++ G++
Sbjct: 89 CF-FGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGES 147
Query: 148 SIILTF---RQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKL 193
T ++L E G G+ KG ++ P++ + + YE LK +
Sbjct: 148 KYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNI 196
>gi|13994341 solute carrier family 25 member 2 [Homo sapiens]
Length = 301
Score = 64.3 bits (155), Expect = 7e-11
Identities = 44/166 (26%), Positives = 81/166 (48%), Gaps = 16/166 (9%)
Query: 37 PFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYH 96
PF I+ ++Q LY G D F+K GLRGFY+G +L+ Y+ ++V + Y
Sbjct: 29 PFDTIKVKMQTFP--DLYKGLTDCFLKTYAQVGLRGFYKGTGPALMAYVAENSVLFMCYG 86
Query: 97 F---YAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ------VEGK- 146
F + +++ + + + A +G A+A A++ P ++++ R+Q + GK
Sbjct: 87 FCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTELVKCRLQTMYEMEMSGKI 146
Query: 147 ----NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYE 188
N+I + ++ ++GP G GLS+ ++ P GYE
Sbjct: 147 AKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPGYFFFFGGYE 192
Score = 56.6 bits (135), Expect = 1e-08
Identities = 50/175 (28%), Positives = 84/175 (48%), Gaps = 11/175 (6%)
Query: 33 VSVYPFTLIRTRLQVQ-----KGK-SLYHGTFDAFIK-ILQADGLRGFYRGYVASLLTYI 85
+++ P L++ RLQ GK + H T + +K IL+ DG GFY G ++LL +
Sbjct: 122 LALCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEV 181
Query: 86 PNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQV-- 143
P ++ Y + K+ V +SG +A ++ P+D I++R+QV
Sbjct: 182 PGYFFFFGGYELSRSFFASGRSKDELGPVHLMLSGGVAGICLWLVVFPVDCIKSRIQVLS 241
Query: 144 -EGKNS-IILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKLSLR 196
GK + I T ++ EG L GL A +I A P+ + V YE +K+ ++
Sbjct: 242 MYGKQAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMMMK 296
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 64.3 bits (155), Expect = 7e-11
Identities = 47/171 (27%), Positives = 79/171 (46%), Gaps = 16/171 (9%)
Query: 35 VYPFTLIRTRLQVQKGKS----LYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAV 90
VYP RTRL GKS + G D +KI ++DG+RG Y+G+ S+ I A
Sbjct: 131 VYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRAA 190
Query: 91 WWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEG--KNS 148
++ Y L + HIV + A A +++ P D +R R+ ++ K +
Sbjct: 191 ---YFGVYDTAKGMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGA 247
Query: 149 IIL------TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKL 193
I+ +R++ +EG KG + ++ V+V+ Y+ LKK+
Sbjct: 248 DIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLVL-YDELKKV 297
Score = 50.8 bits (120), Expect = 8e-07
Identities = 44/173 (25%), Positives = 73/173 (42%), Gaps = 18/173 (10%)
Query: 18 KKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSL------YHGTFDAFIKILQADGLR 71
K F G+A + + +V P ++ LQVQ Y G D ++I + G+
Sbjct: 10 KDFLAGGIAAAIS-KTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVL 68
Query: 72 GFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECP---HIVFQAVSGPLAAATAS 128
F+RG +A+++ Y P A+ + F Y + K + SG A AT+
Sbjct: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSL 128
Query: 129 ILTNPMDVIRTRVQVE-GKNSIILTFR-------QLMAEEGPWGLMKGLSARI 173
P+D RTR+ + GK+ FR ++ +G GL +G S +
Sbjct: 129 CFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSV 181
Score = 38.9 bits (89), Expect = 0.003
Identities = 19/66 (28%), Positives = 37/66 (56%), Gaps = 4/66 (6%)
Query: 21 YVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKS----LYHGTFDAFIKILQADGLRGFYRG 76
++ +T + V YPF +R R+ +Q G+ +Y GT D + KI + +G + F++G
Sbjct: 214 WMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKG 273
Query: 77 YVASLL 82
+++L
Sbjct: 274 AWSNVL 279
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 63.9 bits (154), Expect = 9e-11
Identities = 49/170 (28%), Positives = 78/170 (45%), Gaps = 16/170 (9%)
Query: 35 VYPFTLIRTRLQVQKGKSL----YHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAV 90
VYP RTRL GK +HG D IKI ++DGLRG Y+G+ S+ I A
Sbjct: 131 VYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAA 190
Query: 91 WWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEG--KNS 148
++ Y L PK HI + A A +++ P D +R R+ ++ K +
Sbjct: 191 YFGVYDTAKGMLP--DPKNV-HIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGA 247
Query: 149 IIL------TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 192
I+ +R++ +EG KG + ++ V+V+ Y+ +KK
Sbjct: 248 DIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVL-YDEIKK 296
Score = 47.8 bits (112), Expect = 7e-06
Identities = 44/179 (24%), Positives = 74/179 (41%), Gaps = 20/179 (11%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQ------KGKSLYHGTFDAFIKIL 65
W L K F GVA + + +V P ++ LQVQ + Y G D ++I
Sbjct: 6 WSFL--KDFLAGGVAAAVS-KTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIP 62
Query: 66 QADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKE---CPHIVFQAVSGPL 122
+ G F+RG +A+++ Y P A+ + F Y + + + SG
Sbjct: 63 KEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGA 122
Query: 123 AAATASILTNPMDVIRTRVQVE-GKNSIILTFR-------QLMAEEGPWGLMKGLSARI 173
A AT+ P+D RTR+ + GK + F ++ +G GL +G + +
Sbjct: 123 AGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSV 181
Score = 39.3 bits (90), Expect = 0.002
Identities = 21/76 (27%), Positives = 41/76 (53%), Gaps = 9/76 (11%)
Query: 16 DKKKFYVF-----GVAMTMMIRVSVYPFTLIRTRLQVQKGKS----LYHGTFDAFIKILQ 66
D K ++F ++T + + YPF +R R+ +Q G+ +Y GT D + KI +
Sbjct: 204 DPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAK 263
Query: 67 ADGLRGFYRGYVASLL 82
+G + F++G +++L
Sbjct: 264 DEGAKAFFKGAWSNVL 279
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 63.9 bits (154), Expect = 9e-11
Identities = 49/190 (25%), Positives = 81/190 (42%), Gaps = 17/190 (8%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASL 81
+ G T++ + P +++ RLQ+ S + + + +GL FYR Y L
Sbjct: 148 IAGSMATLLHDAVMNPAEVVKQRLQMYN--SQHRSAISCIRTVWRTEGLGAFYRSYTTQL 205
Query: 82 LTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRV 141
IP ++ + Y F EQ++ P + +SG LA A A+ T P+DV +T +
Sbjct: 206 TMNIPFQSIHFITYEFLQEQVN---PHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLL 262
Query: 142 QVEGKNSIIL------------TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYES 189
+ ++ L FR + G G KG+ AR+I PST + YE
Sbjct: 263 NTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEF 322
Query: 190 LKKLSLRPEL 199
K + +L
Sbjct: 323 FKYFLTKRQL 332
Score = 35.4 bits (80), Expect = 0.034
Identities = 23/80 (28%), Positives = 42/80 (52%), Gaps = 10/80 (12%)
Query: 123 AAATASILTN----PMDVIRTRVQVEGKN------SIILTFRQLMAEEGPWGLMKGLSAR 172
A A A IL + P+D ++TR+Q + SI +++M EG W ++G++
Sbjct: 51 AGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVM 110
Query: 173 IISATPSTIVIVVGYESLKK 192
I+ A P+ + YE++K+
Sbjct: 111 IMGAGPAHAMYFACYENMKR 130
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 63.5 bits (153), Expect = 1e-10
Identities = 45/150 (30%), Positives = 78/150 (52%), Gaps = 15/150 (10%)
Query: 35 VYPFTLIRTRLQVQK---GKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVW 91
++P +++TR Q+Q+ + Y D+F I Q +GL GFY+G + +L P AV
Sbjct: 31 MHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVK 90
Query: 92 WPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKN---- 147
+ + Y + L Y+ P + F A++G + T +I+ NP +V++ +Q
Sbjct: 91 FFTFEQYKKLLGYV--SLSPALTF-AIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQ 147
Query: 148 -SIILTFRQLMAEEGPWGLM---KGLSARI 173
S + RQ++ +EG WGL KGL+A +
Sbjct: 148 PSTVGYARQIIKKEG-WGLQGLNKGLTATL 176
Score = 47.4 bits (111), Expect = 9e-06
Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 11/95 (11%)
Query: 116 QAVSGPLAAATASILTNPMDVIRTRVQVE-------GKNSIILTFRQLMAEEGPWGLMKG 168
Q V+G A L +P+DV++TR Q++ S++ +FR + EG +G KG
Sbjct: 16 QIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKG 75
Query: 169 LSARIISATPSTIVIVVGYESLKKL----SLRPEL 199
+ I++ TP V +E KKL SL P L
Sbjct: 76 ILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPAL 110
Score = 42.7 bits (99), Expect = 2e-04
Identities = 42/181 (23%), Positives = 81/181 (44%), Gaps = 15/181 (8%)
Query: 20 FYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKIL---QADGLRGFYRG 76
F + G+ + + V PF +++ LQ + + + + + + GL+G +G
Sbjct: 112 FAIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKG 171
Query: 77 YVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVF--QAVSGPLAAATASILTNPM 134
A+L + + V++ FY+ + + P + F + G L+ AS++ P
Sbjct: 172 LTATLGRHGVFNMVYFGFYYNVKNMIPV---NKDPILEFWRKFGIGLLSGTIASVINIPF 228
Query: 135 DVIRTRVQ----VEGK---NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGY 187
DV ++R+Q V G+ + T + EEG L KGL +I+ P V+++ Y
Sbjct: 229 DVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVY 288
Query: 188 E 188
E
Sbjct: 289 E 289
>gi|115430257 solute carrier family 25, member 26 [Homo sapiens]
Length = 274
Score = 63.5 bits (153), Expect = 1e-10
Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 20/181 (11%)
Query: 24 GVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLT 83
G + +IRV P +++ R QV TF F IL +G++G YRGY +++L
Sbjct: 98 GEVVACLIRV---PSEVVKQRAQVSASTR----TFQIFSNILYEEGIQGLYRGYKSTVLR 150
Query: 84 YIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQ---AVSGPLAAATASILTNPMDVIRTR 140
IP S V +P + E L L H+V AV G A A+ +T P+DV +TR
Sbjct: 151 EIPFSLVQFPLW----ESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTR 206
Query: 141 VQVEGKNSIILTFRQLMAEEGPW------GLMKGLSARIISATPSTIVIVVGYESLKKLS 194
+ + S L G W GL G+ R+ + + + + Y+ L
Sbjct: 207 IMLAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLL 266
Query: 195 L 195
L
Sbjct: 267 L 267
Score = 60.1 bits (144), Expect = 1e-09
Identities = 44/177 (24%), Positives = 80/177 (45%), Gaps = 28/177 (15%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASL 81
V GV++ +++ +P I+TRLQ +G + +A G G Y G ++
Sbjct: 15 VAGVSVDLIL----FPLDTIKTRLQSPQGFN-------------KAGGFHGIYAGVPSAA 57
Query: 82 LTYIPNSAVWWPFYHF-----YAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDV 136
+ PN+A ++ Y + +A+ SYL P + ++ A ++ P +V
Sbjct: 58 IGSFPNAAAFFITYEYVKWFLHADSSSYLTPMK------HMLAASAGEVVACLIRVPSEV 111
Query: 137 IRTRVQVEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKL 193
++ R QV F ++ EEG GL +G + ++ P ++V +ESLK L
Sbjct: 112 VKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKAL 168
Score = 30.4 bits (67), Expect = 1.1
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 11/82 (13%)
Query: 111 PHIVFQAVSGPLAAATASILTNPMDVIRTRVQ-VEGKNSIILTFRQLMAEEGPWGLMKGL 169
P V V+G +A + ++ P+D I+TR+Q +G N G G+ G+
Sbjct: 4 PGFVAALVAGGVAGVSVDLILFPLDTIKTRLQSPQGFNK----------AGGFHGIYAGV 53
Query: 170 SARIISATPSTIVIVVGYESLK 191
+ I + P+ + YE +K
Sbjct: 54 PSAAIGSFPNAAAFFITYEYVK 75
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 63.5 bits (153), Expect = 1e-10
Identities = 50/185 (27%), Positives = 85/185 (45%), Gaps = 27/185 (14%)
Query: 19 KFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSL--------YHGTFDAFIKILQADGL 70
K +V+G +++ +P L +TRLQVQ G+S+ Y G F A +I + +G+
Sbjct: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQ-GQSIDARFKEIKYRGMFHALFRICKEEGV 100
Query: 71 RGFYRGYVASLLTYIPNSAVWWPFYH----FYAEQLSYLCPKECPHIVFQAVSGPLAAAT 126
Y G +LL + Y + E+L E ++ + G ++
Sbjct: 101 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERL------EDETLLINMICGVVSGVI 154
Query: 127 ASILTNPMDVIRTRVQVEG---KNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVI 183
+S + NP DV++ R+Q +G + S+I +F + +EG GL +G + T I
Sbjct: 155 SSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRG-----VVPTAQRAAI 209
Query: 184 VVGYE 188
VVG E
Sbjct: 210 VVGVE 214
Score = 52.4 bits (124), Expect = 3e-07
Identities = 47/183 (25%), Positives = 78/183 (42%), Gaps = 12/183 (6%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTF-DAFIKILQADGLRGFYRGYVAS 80
+ GV ++ P +++ R+Q Q SL+ G+ +FI I Q +G RG +RG V +
Sbjct: 146 ICGVVSGVISSTIANPTDVLKIRMQAQG--SLFQGSMIGSFIDIYQQEGTRGLWRGVVPT 203
Query: 81 LLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTR 140
V P Y + L L I+ VS ++ +NP+DV+RTR
Sbjct: 204 AQRAAIVVGVELPVYDITKKHL-ILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTR 262
Query: 141 VQ--------VEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 192
+ V+ + ++ EG + L KG + P I+ + YE LK+
Sbjct: 263 MMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
Query: 193 LSL 195
L +
Sbjct: 323 LQI 325
Score = 36.2 bits (82), Expect = 0.020
Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 15/89 (16%)
Query: 118 VSGPLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQ------------LMAEEGPWGL 165
V G LA+ A T P+D+ +TR+QV+G+ SI F++ + EEG L
Sbjct: 45 VYGGLASIVAEFGTFPVDLTKTRLQVQGQ-SIDARFKEIKYRGMFHALFRICKEEGVLAL 103
Query: 166 MKGLSARII-SATPSTIVIVVGYESLKKL 193
G++ ++ A+ TI I + Y+SLK+L
Sbjct: 104 YSGIAPALLRQASYGTIKIGI-YQSLKRL 131
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 63.5 bits (153), Expect = 1e-10
Identities = 50/185 (27%), Positives = 85/185 (45%), Gaps = 27/185 (14%)
Query: 19 KFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSL--------YHGTFDAFIKILQADGL 70
K +V+G +++ +P L +TRLQVQ G+S+ Y G F A +I + +G+
Sbjct: 39 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQ-GQSIDARFKEIKYRGMFHALFRICKEEGV 97
Query: 71 RGFYRGYVASLLTYIPNSAVWWPFYH----FYAEQLSYLCPKECPHIVFQAVSGPLAAAT 126
Y G +LL + Y + E+L E ++ + G ++
Sbjct: 98 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERL------EDETLLINMICGVVSGVI 151
Query: 127 ASILTNPMDVIRTRVQVEG---KNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVI 183
+S + NP DV++ R+Q +G + S+I +F + +EG GL +G + T I
Sbjct: 152 SSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRG-----VVPTAQRAAI 206
Query: 184 VVGYE 188
VVG E
Sbjct: 207 VVGVE 211
Score = 52.4 bits (124), Expect = 3e-07
Identities = 47/183 (25%), Positives = 78/183 (42%), Gaps = 12/183 (6%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTF-DAFIKILQADGLRGFYRGYVAS 80
+ GV ++ P +++ R+Q Q SL+ G+ +FI I Q +G RG +RG V +
Sbjct: 143 ICGVVSGVISSTIANPTDVLKIRMQAQG--SLFQGSMIGSFIDIYQQEGTRGLWRGVVPT 200
Query: 81 LLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTR 140
V P Y + L L I+ VS ++ +NP+DV+RTR
Sbjct: 201 AQRAAIVVGVELPVYDITKKHL-ILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTR 259
Query: 141 VQ--------VEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 192
+ V+ + ++ EG + L KG + P I+ + YE LK+
Sbjct: 260 MMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319
Query: 193 LSL 195
L +
Sbjct: 320 LQI 322
Score = 36.2 bits (82), Expect = 0.020
Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 15/89 (16%)
Query: 118 VSGPLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQ------------LMAEEGPWGL 165
V G LA+ A T P+D+ +TR+QV+G+ SI F++ + EEG L
Sbjct: 42 VYGGLASIVAEFGTFPVDLTKTRLQVQGQ-SIDARFKEIKYRGMFHALFRICKEEGVLAL 100
Query: 166 MKGLSARII-SATPSTIVIVVGYESLKKL 193
G++ ++ A+ TI I + Y+SLK+L
Sbjct: 101 YSGIAPALLRQASYGTIKIGI-YQSLKRL 128
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 63.2 bits (152), Expect = 2e-10
Identities = 46/168 (27%), Positives = 83/168 (49%), Gaps = 15/168 (8%)
Query: 35 VYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPF 94
+ P +++TRL +++ Y G D +ILQ +G R YRGY+ ++L IP +
Sbjct: 204 INPMEVLKTRLTLRR-TGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAV 262
Query: 95 YHFYAEQLSYLCPKE-----CPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ----VEG 145
Y E L K P + S L+ + + P+ ++RTR+Q VEG
Sbjct: 263 Y----EMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEG 318
Query: 146 KNSIIL-TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 192
N + ++++A++G GL +G++ ++ P+ + V YE++KK
Sbjct: 319 SNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
Score = 54.3 bits (129), Expect = 7e-08
Identities = 40/177 (22%), Positives = 75/177 (42%), Gaps = 7/177 (3%)
Query: 19 KFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILQADGLRGFYRGYV 78
KF + G + R P + +QV K+ + ++Q G R +RG
Sbjct: 94 KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNG 153
Query: 79 ASLLTYIPNSAVWWPFYHFYAEQLSYLCP-KECPHIVFQAVSGPLAAATASILTNPMDVI 137
++L P A+ + + + +Y C + P + ++G LA A + L NPM+V+
Sbjct: 154 INVLKIAPEYAI---KFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLINPMEVL 210
Query: 138 RTRVQVEGK---NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 191
+TR+ + ++ RQ++ EG L +G ++ P + YE L+
Sbjct: 211 KTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQ 267
Score = 37.7 bits (86), Expect = 0.007
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 32 RVSVYPFTLIRTRLQVQKGKSLYHGTFDAFI-KILQADGLRGFYRGYVASLLTYIPNSAV 90
+++ YP TL+RTR+Q Q + T + +IL G G YRG +LL +P +
Sbjct: 297 QMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGI 356
Query: 91 WWPFY 95
+ Y
Sbjct: 357 SYVVY 361
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,772,268
Number of Sequences: 37866
Number of extensions: 243843
Number of successful extensions: 1091
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 673
Number of HSP's gapped (non-prelim): 199
length of query: 205
length of database: 18,247,518
effective HSP length: 97
effective length of query: 108
effective length of database: 14,574,516
effective search space: 1574047728
effective search space used: 1574047728
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.