Search of human proteins with 20302155

Search of human proteins with 20302155

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20302155 hyaluronan synthase 3 isoform b [Homo sapiens]
         (281 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20302155 hyaluronan synthase 3 isoform b [Homo sapiens]            564   e-161
gi|20302153 hyaluronan synthase 3 isoform a [Homo sapiens]            493   e-140
gi|4885391 hyaluronan synthase 2 [Homo sapiens]                       313   1e-85
gi|167466171 hyaluronan synthase 1 [Homo sapiens]                     228   5e-60
gi|215820630 MON1 homolog A isoform a [Homo sapiens]                   30   3.1  
gi|62865635 squalene epoxidase [Homo sapiens]                          29   5.3  
gi|51593088 neuroligin 3 [Homo sapiens]                                28   6.9  
gi|197245386 hypothetical protein LOC387856 [Homo sapiens]             28   9.0  

>gi|20302155 hyaluronan synthase 3 isoform b [Homo sapiens]
          Length = 281

 Score =  564 bits (1453), Expect = e-161
 Identities = 281/281 (100%), Positives = 281/281 (100%)

Query: 1   MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS 60
           MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS
Sbjct: 1   MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS 60

Query: 61  LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM 120
           LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM
Sbjct: 61  LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM 120

Query: 121 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA 180
           VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA
Sbjct: 121 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA 180

Query: 181 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG 240
           STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG
Sbjct: 181 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG 240

Query: 241 VGGDVQPPGKGMAVEDDQVQAAQVRATEAWSVHQRHVSREQ 281
           VGGDVQPPGKGMAVEDDQVQAAQVRATEAWSVHQRHVSREQ
Sbjct: 241 VGGDVQPPGKGMAVEDDQVQAAQVRATEAWSVHQRHVSREQ 281


>gi|20302153 hyaluronan synthase 3 isoform a [Homo sapiens]
          Length = 553

 Score =  493 bits (1270), Expect = e-140
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS 60
           MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS
Sbjct: 1   MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS 60

Query: 61  LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM 120
           LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM
Sbjct: 61  LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM 120

Query: 121 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA 180
           VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA
Sbjct: 121 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA 180

Query: 181 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG 240
           STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG
Sbjct: 181 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG 240

Query: 241 VGGDVQ 246
           VGGDVQ
Sbjct: 241 VGGDVQ 246


>gi|4885391 hyaluronan synthase 2 [Homo sapiens]
          Length = 552

 Score =  313 bits (801), Expect = 1e-85
 Identities = 147/238 (61%), Positives = 193/238 (81%), Gaps = 4/238 (1%)

Query: 9   LRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQSLFAFLEHR 68
           LR++GT+LF +++L GI AAY+ GYQFI T+ +Y SFGLYGA L  HL+IQSLFAFLEHR
Sbjct: 10  LRIIGTTLFGVSLLLGITAAYIVGYQFIQTDNYYFSFGLYGAFLASHLIIQSLFAFLEHR 69

Query: 69  RMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVMVVDGNRQE 128
           +M+++   L+ P     +VALCIAAYQEDPDYLRKCL+S +R+++P +KVVMV+DGN ++
Sbjct: 70  KMKKS---LETPIKLNKTVALCIAAYQEDPDYLRKCLQSVKRLTYPGIKVVMVIDGNSED 126

Query: 129 DAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRASTFSCIMQ 188
           D YM+DIF EV+G  +++  ++W++NFHE G GET+ S +E    V  +V ++   CIMQ
Sbjct: 127 DLYMMDIFSEVMG-RDKSATYIWKNNFHEKGPGETDESHKESSQHVTQLVLSNKSICIMQ 185

Query: 189 KWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDVQ 246
           KWGGKREVMYTAF+ALG SVDY+QVCDSDT+LDPA ++EM++VLEEDP VGGVGGDVQ
Sbjct: 186 KWGGKREVMYTAFRALGRSVDYVQVCDSDTMLDPASSVEMVKVLEEDPMVGGVGGDVQ 243


>gi|167466171 hyaluronan synthase 1 [Homo sapiens]
          Length = 578

 Score =  228 bits (581), Expect = 5e-60
 Identities = 127/250 (50%), Positives = 160/250 (64%), Gaps = 15/250 (6%)

Query: 10  RVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQSLFAFLEHRR 69
           R V T  FAL +LG +  AY  G          L+FGLYGA L  HL+ QSLFA+LEHRR
Sbjct: 21  RRVLTIAFALLILGLMTWAYAAGVPLASDRYGLLAFGLYGAFLSAHLVAQSLFAYLEHRR 80

Query: 70  MRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPD--LKVVMVVDGNRQ 127
           +  A +   L +    SVAL I+AYQEDP YLR+CL SA+ + +P   L+V+MVVDGNR 
Sbjct: 81  VAAAARG-PLDAATARSVALTISAYQEDPAYLRQCLASARALLYPRARLRVLMVVDGNRA 139

Query: 128 EDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDR-----------VRD 176
           ED YM+D+F EV    + A + VW  N+H+  E     ++  G  R           V  
Sbjct: 140 EDLYMVDMFREVFADEDPATY-VWDGNYHQPWEPAAAGAVGAGAYREVEAEDPGRLAVEA 198

Query: 177 VVRASTFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDP 236
           +VR     C+ Q+WGGKREVMYTAFKALGDSVDY+QVCDSDT LDP   +E++RVL+EDP
Sbjct: 199 LVRTRRCVCVAQRWGGKREVMYTAFKALGDSVDYVQVCDSDTRLDPMALLELVRVLDEDP 258

Query: 237 QVGGVGGDVQ 246
           +VG VGGDV+
Sbjct: 259 RVGAVGGDVR 268


>gi|215820630 MON1 homolog A isoform a [Homo sapiens]
          Length = 652

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 9/54 (16%)

Query: 227 EMLRVLEED--PQVGGVGGDV-QPPGKGMAVEDDQVQAAQVRATEAWSVHQRHV 277
           EML    ED     G VG    +PP +G    D++       ATEAW +HQ+HV
Sbjct: 208 EMLPGSSEDWLEPPGAVGRPATEPPREGTTEGDEE------DATEAWRLHQKHV 255


>gi|62865635 squalene epoxidase [Homo sapiens]
          Length = 574

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 33/158 (20%), Positives = 59/158 (37%), Gaps = 11/158 (6%)

Query: 126 RQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRASTFSC 185
           RQ+      +F ++L G    GFF  +S      + + EA  +     + +     T +C
Sbjct: 56  RQQSGSQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAAC 115

Query: 186 IMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDV 245
                    EV+      LG ++  +   D   V      IE  R L+E  ++  VG  +
Sbjct: 116 TSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKV----TVIE--RDLKEPDRI--VGEFL 167

Query: 246 QPPGKGMAVE---DDQVQAAQVRATEAWSVHQRHVSRE 280
           QP G  +  +    D V+    +    + +H +    E
Sbjct: 168 QPGGYHVLKDLGLGDTVEGLDAQVVNGYMIHDQESKSE 205


>gi|51593088 neuroligin 3 [Homo sapiens]
          Length = 828

 Score = 28.5 bits (62), Expect = 6.9
 Identities = 17/48 (35%), Positives = 29/48 (60%), Gaps = 2/48 (4%)

Query: 52  LGLHLLIQSLFAF--LEHRRMRRAGQALKLPSPRRGSVALCIAAYQED 97
           +G  LL  ++ AF  L +R+ +R  + L+ PSP+RG+ A  + A  E+
Sbjct: 694 VGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAPEE 741


>gi|197245386 hypothetical protein LOC387856 [Homo sapiens]
          Length = 194

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%)

Query: 203 ALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDVQPPGKGMAVEDDQ 258
           AL +   +IQV   D   +    + M +++   P+ GG+G      GKG    D Q
Sbjct: 64  ALDEQASHIQVLSDDVCANQRAIVSMCQIMTTAPRQGGLG---VVGGKGSFQSDPQ 116


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,384,768
Number of Sequences: 37866
Number of extensions: 439250
Number of successful extensions: 1022
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1012
Number of HSP's gapped (non-prelim): 8
length of query: 281
length of database: 18,247,518
effective HSP length: 101
effective length of query: 180
effective length of database: 14,423,052
effective search space: 2596149360
effective search space used: 2596149360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.