Search of human proteins with 19923245

Search of human proteins with 19923245

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923245 corticotropin releasing hormone receptor 1 isoform
2 [Homo sapiens]
         (415 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923245 corticotropin releasing hormone receptor 1 isoform 2...   856   0.0  
gi|223717971 corticotropin releasing hormone receptor 1 isoform ...   840   0.0  
gi|223717985 corticotropin releasing hormone receptor 1 isoform ...   816   0.0  
gi|223717978 corticotropin releasing hormone receptor 1 isoform ...   747   0.0  
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap...   608   e-174
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]    214   9e-56
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]   202   5e-52
gi|114205383 secretin receptor precursor [Homo sapiens]               200   2e-51
gi|4502547 calcitonin receptor [Homo sapiens]                         199   4e-51
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]    196   2e-50
gi|4503947 glucagon receptor [Homo sapiens]                           196   4e-50
gi|5031621 calcitonin receptor-like [Homo sapiens]                    187   1e-47
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi...   186   3e-47
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]   182   4e-46
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]          181   1e-45
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar...   179   3e-45
gi|58530851 growth hormone releasing hormone receptor isoform a ...   177   1e-44
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]     173   3e-43
gi|58530853 growth hormone releasing hormone receptor isoform b ...   125   9e-29
gi|163792198 latrophilin 3 precursor [Homo sapiens]                   105   6e-23
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]             102   6e-22
gi|133930786 egf-like module-containing mucin-like receptor 3 [H...   101   1e-21
gi|40807489 egf-like module containing, mucin-like, hormone rece...    89   6e-18
gi|6912464 latrophilin 2 precursor [Homo sapiens]                      89   7e-18
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...    88   1e-17
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]      87   3e-17
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]           85   1e-16
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]           85   1e-16
gi|23397681 egf-like module containing, mucin-like, hormone rece...    85   1e-16
gi|23397693 egf-like module containing, mucin-like, hormone rece...    85   1e-16

>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
           [Homo sapiens]
          Length = 415

 Score =  856 bits (2211), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60
           MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA
Sbjct: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60

Query: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120
           GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
Sbjct: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120

Query: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
           IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV
Sbjct: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180

Query: 181 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240
           HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF
Sbjct: 181 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240

Query: 241 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 300
           PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA
Sbjct: 241 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 300

Query: 301 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVS 360
           STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVS
Sbjct: 301 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVS 360

Query: 361 VFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 415
           VFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
Sbjct: 361 VFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 415


>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
           [Homo sapiens]
          Length = 444

 Score =  840 bits (2171), Expect = 0.0
 Identities = 415/444 (93%), Positives = 415/444 (93%), Gaps = 29/444 (6%)

Query: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60
           MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA
Sbjct: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60

Query: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120
           GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
Sbjct: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120

Query: 121 IINYLGHCISLVALLVAFVLFLRLR-----------------------------SIRCLR 151
           IINYLGHCISLVALLVAFVLFLRLR                             SIRCLR
Sbjct: 121 IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR 180

Query: 152 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 211
           NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC
Sbjct: 181 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 240

Query: 212 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 271
           YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI
Sbjct: 241 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 300

Query: 272 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 331
           YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF
Sbjct: 301 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 360

Query: 332 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV 391
           VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV
Sbjct: 361 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV 420

Query: 392 ARAMSIPTSPTRVSFHSIKQSTAV 415
           ARAMSIPTSPTRVSFHSIKQSTAV
Sbjct: 421 ARAMSIPTSPTRVSFHSIKQSTAV 444


>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
           [Homo sapiens]
          Length = 401

 Score =  816 bits (2109), Expect = 0.0
 Identities = 401/415 (96%), Positives = 401/415 (96%), Gaps = 14/415 (3%)

Query: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60
           MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA
Sbjct: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60

Query: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120
           GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
Sbjct: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120

Query: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
           IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV
Sbjct: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180

Query: 181 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240
           HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF
Sbjct: 181 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240

Query: 241 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 300
           PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA
Sbjct: 241 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 300

Query: 301 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVS 360
           STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQ     
Sbjct: 301 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQ----- 355

Query: 361 VFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 415
                    VRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
Sbjct: 356 ---------VRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 401


>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
           [Homo sapiens]
          Length = 375

 Score =  747 bits (1929), Expect = 0.0
 Identities = 374/415 (90%), Positives = 375/415 (90%), Gaps = 40/415 (9%)

Query: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60
           MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNIS                    
Sbjct: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNIS-------------------- 40

Query: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120
                               +NGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
Sbjct: 41  --------------------DNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 80

Query: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
           IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV
Sbjct: 81  IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 140

Query: 181 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240
           HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF
Sbjct: 141 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 200

Query: 241 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 300
           PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA
Sbjct: 201 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 260

Query: 301 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVS 360
           STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVS
Sbjct: 261 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVS 320

Query: 361 VFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 415
           VFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
Sbjct: 321 VFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 375


>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
           sapiens]
          Length = 411

 Score =  608 bits (1569), Expect = e-174
 Identities = 278/373 (74%), Positives = 329/373 (88%), Gaps = 2/373 (0%)

Query: 44  CNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQ 103
           CN ++D IGTCWPRS AG LV RPCP +F GV+YNTT N YRECL NG+WA+++NYS+C+
Sbjct: 40  CNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCE 99

Query: 104 EILNE-EKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAF 162
            IL++ ++K  +HY +A+++NYLGHC+S+ AL+ AF+LFL LRSIRCLRN+IHWNLI+ F
Sbjct: 100 PILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTF 159

Query: 163 ILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYS 222
           ILRN  WF++QL +  EVH+SN  WCR +T  +NYF VTNFFWMF EGCYLHTAIV+TYS
Sbjct: 160 ILRNVMWFLLQL-VDHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYS 218

Query: 223 TDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLI 282
           T+RLRK +F+ IGW +PFPIIVAWAIGKLYY+NE+CWFGK PG   DYIYQGP+ILVLLI
Sbjct: 219 TERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLI 278

Query: 283 NFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRV 342
           NF+FLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGED++S++
Sbjct: 279 NFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQI 338

Query: 343 VFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPT 402
           +FIYFNSFL+SFQGFFVSVFYCF N EVRSA+RKRWHRWQD HS+R  +ARAMSIPTSPT
Sbjct: 339 MFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPT 398

Query: 403 RVSFHSIKQSTAV 415
           R+SFHSIKQ+ AV
Sbjct: 399 RISFHSIKQTAAV 411


>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
          Length = 593

 Score =  214 bits (546), Expect = 9e-56
 Identities = 125/383 (32%), Positives = 184/383 (48%), Gaps = 44/383 (11%)

Query: 37  SNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWA-- 94
           S   G  C    D I  CWP    G++V  PCP + Y   +N   + YR C  NGSW   
Sbjct: 101 SRYRGRPCLPEWDHI-LCWPLGAPGEVVAVPCPDYIYD--FNHKGHAYRRCDRNGSWELV 157

Query: 95  -----ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRC 149
                   NYSEC + L  E + +  +    +I  +G+ +SL +L VA ++    R + C
Sbjct: 158 PGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHC 217

Query: 150 LRNIIHWNLISAFILRNATWFV-------------------------VQLTMSPEVHQSN 184
            RN IH +L  +F+LR  + FV                          Q    P    + 
Sbjct: 218 TRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAG 277

Query: 185 VGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIV 244
              CR+    + YF  TN++W+  EG YLH+ I + + +++   W F   GWG+P   + 
Sbjct: 278 YAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVA 337

Query: 245 AWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLR---AS 301
            W   +    N  CW          +I Q P++  +++NFI   NIVR+L TKLR   A 
Sbjct: 338 VWVSVRATLANTGCW--DLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAG 395

Query: 302 TTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVF---IYFNSFLESFQGFF 358
                 QYRK +K+TLVL+PL G+ Y++F   P   EVS  ++   +++     SFQGFF
Sbjct: 396 RCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATP-YTEVSGTLWQVQMHYEMLFNSFQGFF 454

Query: 359 VSVFYCFLNSEVRSAIRKRWHRW 381
           V++ YCF N EV++ I+K W RW
Sbjct: 455 VAIIYCFCNGEVQAEIKKSWSRW 477


>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
          Length = 457

 Score =  202 bits (514), Expect = 5e-52
 Identities = 114/344 (33%), Positives = 184/344 (53%), Gaps = 23/344 (6%)

Query: 53  TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYREC-------LANGSWAARVNYSECQEI 105
           TCWP +P GQ+VV  CP  F         N  R C       L  G +       +    
Sbjct: 71  TCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAAS 130

Query: 106 LNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFIL 164
           L+E++     ++ +V   Y +G+ +SL  LLVA  +    R + C RN IH +L  +FIL
Sbjct: 131 LDEQQTM---FYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFIL 187

Query: 165 RNATWFVVQLTM-----SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVL 219
           R A  F+  L +     S +  + +VG C+     + Y  + NFFW+  EG YL+T + +
Sbjct: 188 RAAAVFIKDLALFDSGESDQCSEGSVG-CKAAMVFFQYCVMANFFWLLVEGLYLYTLLAV 246

Query: 220 TYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILV 279
           ++ ++R   W +I IGWGVP    + W I ++++++  CW      ++  +I +GP++  
Sbjct: 247 SFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLW--WIIKGPILTS 304

Query: 280 LLINFIFLFNIVRILMTKLRAS--TTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGED 337
           +L+NFI    I+RIL+ KLR      S++  Y +  ++TL+L+PL G+ Y++F   P  D
Sbjct: 305 ILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFP--D 362

Query: 338 EVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 381
                V + F   + SFQGF V++ YCFLN EV++ +R++W RW
Sbjct: 363 NFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRW 406


>gi|114205383 secretin receptor precursor [Homo sapiens]
          Length = 440

 Score =  200 bits (509), Expect = 2e-51
 Identities = 121/343 (35%), Positives = 190/343 (55%), Gaps = 24/343 (6%)

Query: 53  TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNG--YRECLANGSWAA---RVNYSECQEILN 107
           +CWP S  G++V   CP F   +R  T+ NG  +R C  +G W+    R N + C   +N
Sbjct: 74  SCWPSSVPGRMVEVECPRF---LRMLTSRNGSLFRNCTQDG-WSETFPRPNLA-CGVNVN 128

Query: 108 EEKKSKVH-YHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILR 165
           +    K H Y + + + Y +G+  SLV LLVA  +    R + C RN IH +L  +FILR
Sbjct: 129 DSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILR 188

Query: 166 NATWFVVQLTM--SPEVHQSNV--GWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTY 221
             + F+    +  S +V   +     C+LV   + Y  + N+ W+  EG YLHT + +++
Sbjct: 189 ALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISF 248

Query: 222 STDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCW-FGKRPGVYTDYIYQGPMILVL 280
            ++R     F+  GWG P   +  WAI + + ++  CW       ++  +I +GP+IL +
Sbjct: 249 FSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIW--WIIRGPVILSI 306

Query: 281 LINFIFLFNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDE 338
           LINFI   NI+RILM KLR   T  +E   Y++  ++TL+L+PL GI Y++F  +P   E
Sbjct: 307 LINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSP---E 363

Query: 339 VSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 381
            +  + ++F   L SFQG  V+V YCFLN EV+  ++K+W +W
Sbjct: 364 DAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQW 406


>gi|4502547 calcitonin receptor [Homo sapiens]
          Length = 474

 Score =  199 bits (506), Expect = 4e-51
 Identities = 119/372 (31%), Positives = 196/372 (52%), Gaps = 28/372 (7%)

Query: 41  GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV--- 97
           G  CN + D    CW  +PAG L  + CP +F    ++ +    + C   G W       
Sbjct: 69  GPYCNRTWDG-WLCWDDTPAGVLSYQFCPDYFPD--FDPSEKVTKYCDEKGVWFKHPENN 125

Query: 98  ----NYSECQEILNEE-KKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRN 152
               NY+ C     E+ K + V Y++A++    GH +S+  L+++  +F+  RS+ C R 
Sbjct: 126 RTWSNYTMCNAFTPEKLKNAYVLYYLAIV----GHSLSIFTLVISLGIFVFFRSLGCQRV 181

Query: 153 IIHWNLISAFILRNATWFV--VQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEG 210
            +H N+   +IL +    +  V++  + E+ + +   C+++   + Y    N+FWM  EG
Sbjct: 182 TLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEG 241

Query: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270
            YLHT IV+   T++ R   +  +GWG P       AI +  Y N+ CW      +   Y
Sbjct: 242 IYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLL--Y 299

Query: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLF 330
           I  GP++  L++NF FL NIVR+L+TK+R +  +E+  Y KAVKAT++L+PLLGI +++F
Sbjct: 300 IIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVF 359

Query: 331 FVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRW--------HRWQ 382
              P    + + ++ Y    L  FQGFFV+  YCF N+EV++ ++++W         RW 
Sbjct: 360 PWRPSNKMLGK-IYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWG 418

Query: 383 DKHSIRARVARA 394
            + S R+  A A
Sbjct: 419 RRPSNRSARAAA 430


>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
          Length = 550

 Score =  196 bits (499), Expect = 2e-50
 Identities = 113/364 (31%), Positives = 175/364 (48%), Gaps = 40/364 (10%)

Query: 54  CWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSW-------AARVNYSECQEIL 106
           CWPR   G++   PCP + Y   +N     +R C  NG+W           NYS+C   L
Sbjct: 72  CWPRGTVGKISAVPCPPYIYD--FNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFL 129

Query: 107 NEEKK-SKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFIL 164
             +    K  +   + + Y +G+ IS  +L VA ++    R + C RN IH +L  +F+L
Sbjct: 130 QPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFML 189

Query: 165 RNATWFVVQLTM-----------------------SPEVHQSNVGWCRLVTAAYNYFHVT 201
           R  + FV    +                       +  V +S    C++    + YF  T
Sbjct: 190 RATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLAT 249

Query: 202 NFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFG 261
           N++W+  EG YLH  I + + +D    W FI IGWG P   + AWA+ +    + +CW  
Sbjct: 250 NYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWEL 309

Query: 262 KRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKL---RASTTSETIQYRKAVKATLV 318
               +   +IYQ P++  + +NFI   N VR+L TK+    A       QYRK  K+TLV
Sbjct: 310 SAGDI--KWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLV 367

Query: 319 LLPLLGITYMLFFVNPGE-DEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKR 377
           L+ + G+ Y++F   P     +   + ++   F  SFQGFFVS+ YC+ N EV++ ++K 
Sbjct: 368 LVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKM 427

Query: 378 WHRW 381
           W RW
Sbjct: 428 WSRW 431


>gi|4503947 glucagon receptor [Homo sapiens]
          Length = 477

 Score =  196 bits (497), Expect = 4e-50
 Identities = 132/417 (31%), Positives = 201/417 (48%), Gaps = 42/417 (10%)

Query: 5   PQLRLVKALLLLGLNPVSASLQ-------------DQHCESLSLASNISGLQCNASVDLI 51
           PQ  L+  LLLL   P   S Q             DQ   +LSL    + L CN + D  
Sbjct: 6   PQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKY 65

Query: 52  GTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV------NYSECQ-- 103
            +CWP +PA       CP +            ++ C  +G W          + S+CQ  
Sbjct: 66  -SCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMD 124

Query: 104 -EILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAF 162
            E +  +K+    Y    ++  +G+ +SL ALL+A  +   L  + C RN IH NL ++F
Sbjct: 125 GEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASF 184

Query: 163 ILRNATWFVVQ--------------LTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFG 208
           +L+ ++  V+               L++S  +    V  CR+      Y  V N+ W+  
Sbjct: 185 VLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLV 244

Query: 209 EGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGK-RPGVY 267
           EG YLH  + L    +R    +++ IGWG P   +V WA+ K  ++N +CW      G +
Sbjct: 245 EGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFW 304

Query: 268 TDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITY 327
             +I + P+ L +LINF     IV++L+ KLRA     T    +  K+TL L+PLLG+  
Sbjct: 305 --WILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHE 362

Query: 328 MLF-FVNPGEDE-VSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQ 382
           ++F FV     +   R   ++F+ FL SFQG  V+V YCFLN EV+S +R+RWHRW+
Sbjct: 363 VVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWR 419


>gi|5031621 calcitonin receptor-like [Homo sapiens]
          Length = 461

 Score =  187 bits (476), Expect = 1e-47
 Identities = 111/352 (31%), Positives = 184/352 (52%), Gaps = 20/352 (5%)

Query: 41  GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAAR---- 96
           G+ CN + D    CW    AG   ++ CP +F    ++ +    + C  +G+W       
Sbjct: 62  GVYCNRTWDG-WLCWNDVAAGTESMQLCPDYFQD--FDPSEKVTKICDQDGNWFRHPASN 118

Query: 97  ---VNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNI 153
               NY++C    +E+ K+ ++     II   GH +S+ +LL++  +F   +S+ C R  
Sbjct: 119 RTWTNYTQCNVNTHEKVKTALNLFYLTII---GHGLSIASLLISLGIFFYFKSLSCQRIT 175

Query: 154 IHWNLISAFILRNATWFVVQLTM---SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEG 210
           +H NL  +F+  N+   ++ LT    +  +  +N   C++    + Y    N+FWM  EG
Sbjct: 176 LHKNLFFSFVC-NSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEG 234

Query: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270
            YLHT IV+    ++     +  +GWG P       AI +  Y N+ CW       +  Y
Sbjct: 235 IYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISS--DTHLLY 292

Query: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLF 330
           I  GP+   LL+N  FL NIVR+L+TKL+ +  +E+  Y KAV+ATL+L+PLLGI ++L 
Sbjct: 293 IIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLI 352

Query: 331 FVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQ 382
              P E +++  V+ Y    L  FQG  VS  +CF N EV++ +R+ W++++
Sbjct: 353 PWRP-EGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK 403


>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
           sapiens]
          Length = 553

 Score =  186 bits (472), Expect = 3e-47
 Identities = 128/415 (30%), Positives = 199/415 (47%), Gaps = 45/415 (10%)

Query: 3   GHPQLRLVKALLLLGLNPVSASLQDQHCESLS---------LASNISGLQCNASVDLIGT 53
           G P L LV   LL+ +  V+ SL ++     +         L    SG+ CN + D    
Sbjct: 49  GRPFLTLV---LLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQY-V 104

Query: 54  CWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNY-------SECQEIL 106
           CWP S  G + V PCP++       ++   YR CLA G+W    N        SEC E  
Sbjct: 105 CWPHSSPGNVSV-PCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSE-- 161

Query: 107 NEEKKSKVHYHVAV----IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAF 162
           N   K  V  +  +    ++  +G+  SL++L +A  L L LR + C RN IH NL ++F
Sbjct: 162 NHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASF 221

Query: 163 ILRNATWFVVQLTMSPEVHQ---SNVGW----------CRLVTAAYNYFHVTNFFWMFGE 209
           ILR     V  +       +   +  GW          CR V    +YF   N+ W+  E
Sbjct: 222 ILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVE 281

Query: 210 GCYLHTAIVLTYSTDRLRKW-MFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYT 268
           G YLHT +  T   +R R W  ++ +GW  P   +V W   + + +N  CW         
Sbjct: 282 GLYLHTLLEPTVLPER-RLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCW-TTNGNKKI 339

Query: 269 DYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYM 328
            +I +GPM+L + +NF     I+++L++KL+A          +  K+TLVL+PLLG+  +
Sbjct: 340 WWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEI 399

Query: 329 LF-FVNPGEDE-VSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 381
           LF F+   + E  ++++ ++    L SF GF V++ Y F N EV++ +RK W R+
Sbjct: 400 LFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRF 454


>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
          Length = 438

 Score =  182 bits (463), Expect = 4e-46
 Identities = 115/364 (31%), Positives = 185/364 (50%), Gaps = 18/364 (4%)

Query: 26  QDQHCESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYR 85
           ++  C  L  +       C+   D I TCW  +  G+ V  PCP  F    Y+   N  +
Sbjct: 34  EETKCAELLRSQTEKHKACSGVWDNI-TCWRPANVGETVTVPCPKVFSNF-YSKAGNISK 91

Query: 86  ECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRL 144
            C ++G      ++ +     + E +SK+ +++ V   Y LG+ +SL++L    ++    
Sbjct: 92  NCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLF 151

Query: 145 RSIRCLRNIIHWNLISAFILRNATWFVVQLTM--------SPEVHQSNVGWCRLVTAAYN 196
           R + C RN IH NL  +FILR  +  V    +         P+   S VG C+L      
Sbjct: 152 RKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVG-CKLSLVFLQ 210

Query: 197 YFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNE 256
           Y  + NFFW+  EG YLHT +V      R     ++ IGWG+P   I AW   +LY ++ 
Sbjct: 211 YCIMANFFWLLVEGLYLHTLLVAMLPPRRCFL-AYLLIGWGLPTVCIGAWTAARLYLEDT 269

Query: 257 KCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT--SETIQYRKAVK 314
            CW      V   ++ + P+++ +++NF+   +I+RIL+ KL +     ++  QY++  K
Sbjct: 270 GCWDTNDHSVPW-WVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAK 328

Query: 315 ATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAI 374
           +TL+L+PL G+ YM+F V P    +S    I F   L SFQG  V+V YCFLNSEV+  +
Sbjct: 329 STLLLIPLFGVHYMVFAVFP--ISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCEL 386

Query: 375 RKRW 378
           +++W
Sbjct: 387 KRKW 390


>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
          Length = 463

 Score =  181 bits (458), Expect = 1e-45
 Identities = 116/374 (31%), Positives = 183/374 (48%), Gaps = 39/374 (10%)

Query: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVN--- 98
           L CN + D    CWP    G  V   CP +          + YR C A G W  + N   
Sbjct: 60  LFCNRTFDEYA-CWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSL 118

Query: 99  ----YSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNI 153
                SEC+E    E+ S     + + I Y +G+ +S  AL++A  + L  R + C RN 
Sbjct: 119 PWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNY 178

Query: 154 IHWNLISAFILRNATWFVVQLTM------SPEVHQSNVGW-----------CRLVTAAYN 196
           IH NL ++FILR  + F+    +      + + HQ    W           CRLV     
Sbjct: 179 IHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQ----WDGLLSYQDSLSCRLVFLLMQ 234

Query: 197 YFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNE 256
           Y    N++W+  EG YL+T +  +  +++    +++ IGWGVP   +V W I K  Y++E
Sbjct: 235 YCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDE 294

Query: 257 KCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKAT 316
            CW  +   +    I + P++  + +NF+    ++ I+++KL+A+   +T    +  K+T
Sbjct: 295 GCW-TRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKST 353

Query: 317 LVLLPLLGITYMLF-FVNPGEDEVSRVVFIYFNSFLE----SFQGFFVSVFYCFLNSEVR 371
           L L+PLLG   ++F FV    DE +R    +   F E    SFQG  V++ YCF+N+EV+
Sbjct: 354 LTLIPLLGTHEVIFAFV---MDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQ 410

Query: 372 SAIRKRWHRWQDKH 385
              RK W RW+ +H
Sbjct: 411 LEFRKSWERWRLEH 424


>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
           receptor type I precursor [Homo sapiens]
          Length = 468

 Score =  179 bits (455), Expect = 3e-45
 Identities = 125/419 (29%), Positives = 201/419 (47%), Gaps = 58/419 (13%)

Query: 12  ALLLLGLNPVSAS------LQDQHCESLSLASNISGLQ-----CNASVDLIGTCWPRSPA 60
           ALLLL + P   S       Q    E +  A+ + G       C    D I TCW  +  
Sbjct: 11  ALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNI-TCWKPAHV 69

Query: 61  GQLVVRPCPAFF------------------YG------------VRYNTTNNGYRECLAN 90
           G++V+  CP  F                  +G            V  N T +G+ E   +
Sbjct: 70  GEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPH 129

Query: 91  GSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRC 149
              A   +  E       E   + +Y+++V   Y +G+  SLV L  A V+  R R + C
Sbjct: 130 YFDACGFDEYE------SETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHC 183

Query: 150 LRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSN----VGWCRLVTAAYNYFHVTNFFW 205
            RN IH NL  +F+LR  + F+    +  E   ++       C+ V   ++Y  V+N+FW
Sbjct: 184 TRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFW 243

Query: 206 MFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPG 265
           +F EG YL T +V T+  +R   + +  IGWG P   +  WA  +LY+D+  CW      
Sbjct: 244 LFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCW-DMNDS 302

Query: 266 VYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPLL 323
               ++ +GP++  +++NF+    I+ IL+ KL++     +E+  Y +  ++TL+L+PL 
Sbjct: 303 TALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLF 362

Query: 324 GITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQ 382
           GI Y +F  +P  + VS+   + F   L SFQGF V+V YCFLN EV++ I+++W  W+
Sbjct: 363 GIHYTVFAFSP--ENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWK 419


>gi|58530851 growth hormone releasing hormone receptor isoform a
           precursor [Homo sapiens]
          Length = 423

 Score =  177 bits (450), Expect = 1e-44
 Identities = 115/351 (32%), Positives = 174/351 (49%), Gaps = 24/351 (6%)

Query: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94
           L C A+ D +  CWP + +G+ V  PCP FF         V+ + T  G+ E       A
Sbjct: 53  LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111

Query: 95  ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNII 154
             V      E+L EE+    ++    II  +GH IS+VAL VA  + + LR + C RN +
Sbjct: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYV 164

Query: 155 HWNLISAFILRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEG 210
           H  L + FIL+    F+    +       +  +    C++  AA ++  +TNF W+  E 
Sbjct: 165 HTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEA 224

Query: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270
            YL+  +  T  + R   W  +  GWG+P      W   KL +++  CW       Y  +
Sbjct: 225 VYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-W 283

Query: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTS--ETIQYRKAVKATLVLLPLLGITYM 328
           I +GP++L + +NF    NI+RIL+ KL  +  S     QY +  K+TL L+PL GI Y+
Sbjct: 284 IIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYI 343

Query: 329 LFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWH 379
           +F   P  D     + +     L SFQGF V++ YCFLN EVR+ I ++WH
Sbjct: 344 IFNFLP--DNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWH 392


>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
          Length = 466

 Score =  173 bits (438), Expect = 3e-43
 Identities = 112/376 (29%), Positives = 183/376 (48%), Gaps = 26/376 (6%)

Query: 31  ESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLAN 90
           E+L+ A   SGL CN S D+   CW  +         CP +     +       R+C ++
Sbjct: 48  ETLAAAEPPSGLACNGSFDMY-VCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSD 106

Query: 91  GSWAARVNYSECQEILNEEKKS-----KVHYHVAVIINYLGHCISLVALLVAFVLFLRLR 145
           G W    ++++C+   N EK       ++      ++  +G+ +SL  LL+A ++    R
Sbjct: 107 GQWGLWRDHTQCE---NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFR 163

Query: 146 SIRCLRNIIHWNLISAFILRNATWFVV-QLTMSPEVH---QSNVGW------CRLVTAAY 195
            + C RN IH NL ++F+LR A      +L   P  +   Q+   W      CR      
Sbjct: 164 RLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVT 223

Query: 196 NYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDN 255
            Y    N+ W+  EG YLH+ +VL   ++      ++ +GWG P   ++ W I +  Y+N
Sbjct: 224 QYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYEN 283

Query: 256 EKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKA 315
            +CW          +I + P+++ +LINF+    I+ IL++KLR           +  ++
Sbjct: 284 TQCWERNEVKAIW-WIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARS 342

Query: 316 TLVLLPLLGITYMLFFVNPGEDEVSRVVFIY----FNSFLESFQGFFVSVFYCFLNSEVR 371
           TL L+PLLG+  ++F   P  +E +R    +    F  FL SFQGF VSV YCF+N EV+
Sbjct: 343 TLTLVPLLGVHEVVF--APVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQ 400

Query: 372 SAIRKRWHRWQDKHSI 387
           S IR+ WH  + + S+
Sbjct: 401 SEIRRGWHHCRLRRSL 416


>gi|58530853 growth hormone releasing hormone receptor isoform b
           precursor [Homo sapiens]
          Length = 337

 Score =  125 bits (313), Expect = 9e-29
 Identities = 83/274 (30%), Positives = 130/274 (47%), Gaps = 20/274 (7%)

Query: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94
           L C A+ D +  CWP + +G+ V  PCP FF         V+ + T  G+ E       A
Sbjct: 53  LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111

Query: 95  ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNII 154
             V      E+L EE+    ++    II  +GH IS+VAL VA  + + LR + C RN +
Sbjct: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYV 164

Query: 155 HWNLISAFILRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEG 210
           H  L + FIL+    F+    +       +  +    C++  AA ++  +TNF W+  E 
Sbjct: 165 HTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEA 224

Query: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270
            YL+  +  T  + R   W  +  GWG+P      W   KL +++  CW       Y  +
Sbjct: 225 VYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-W 283

Query: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTS 304
           I +GP++L + +NF    NI+RIL+ KL  +  S
Sbjct: 284 IIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGS 317


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score =  105 bits (263), Expect = 6e-23
 Identities = 90/322 (27%), Positives = 143/322 (44%), Gaps = 40/322 (12%)

Query: 74   GVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVA 133
            G R  TTN  +  C  N       N++     +  +    VH  +  +I ++G  +SLV 
Sbjct: 836  GCRLLTTNKTHTTCSCNHL----TNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVC 891

Query: 134  LLVAFVLFLRLRSIRCLRNIIHWNL-ISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVT 192
            LL+    F   R ++  RN IH NL IS F+        +  T  P         C +  
Sbjct: 892  LLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIA-------CAVFA 944

Query: 193  AAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPII-VAWAIGKL 251
            A  ++F +  F WMF EG  L+  +V  + ++  R+  F  +G+G+P  I+ V+ A+   
Sbjct: 945  ALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYR 1004

Query: 252  YYDNEK-CWFGKRPGVYTDYIYQGPMILVLLINFIFL-------FNIVRILMTKLRASTT 303
             Y  +K CW   R   Y  + + GP  L++++N IFL       F+   IL  +   S  
Sbjct: 1005 SYGTDKVCWL--RLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPE---SGC 1059

Query: 304  SETIQY-------RKAVKATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSFLESF 354
             + I Y       +  V   + LL LLG+T+   L ++N      S V+  Y  +   S 
Sbjct: 1060 LDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINE-----STVIMAYLFTIFNSL 1114

Query: 355  QGFFVSVFYCFLNSEVRSAIRK 376
            QG F+ +F+C L  +VR    K
Sbjct: 1115 QGMFIFIFHCVLQKKVRKEYGK 1136


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score =  102 bits (254), Expect = 6e-22
 Identities = 71/271 (26%), Positives = 133/271 (49%), Gaps = 26/271 (9%)

Query: 122 INYLGHCISLVALLVAFVLFLRLRSIRCLRNI---IHWNLISAFILRNATWFVVQLTMSP 178
           I+Y+G  +S++ L+   V F  L S+  +RN    IH NL  A ++      ++   + P
Sbjct: 569 ISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVL-LLISFRLEP 627

Query: 179 EVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGV 238
                    C+++    +YF ++ F WM  EG +L++ ++  + ++  +   +  +GWG 
Sbjct: 628 GTTP-----CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGF 682

Query: 239 PFPIIV---AWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILM 295
           P  I +   ++A+   Y  +  CW     G    ++   P + V+++N   L  + R++ 
Sbjct: 683 PLLICIISLSFAMDS-YGTSNNCWLSLASGAIWAFV--APALFVIVVNIGILIAVTRVI- 738

Query: 296 TKLRASTTS---ETIQYRKAVKATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSF 350
           +++ A       +   ++   KA  VLLP+LG +++  +  VN        VVF Y  + 
Sbjct: 739 SQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNG-----CAVVFQYMFAT 793

Query: 351 LESFQGFFVSVFYCFLNSEVRSAIRKRWHRW 381
           L S QG F+ +F+C LNSEVR+A + +   W
Sbjct: 794 LNSLQGLFIFLFHCLLNSEVRAAFKHKTKVW 824


>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
           sapiens]
          Length = 652

 Score =  101 bits (251), Expect = 1e-21
 Identities = 82/274 (29%), Positives = 129/274 (47%), Gaps = 25/274 (9%)

Query: 118 VAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMS 177
           V  +I Y+G  +SL+ LL+A + FL  ++IR     +H  L     L +  + V      
Sbjct: 355 VLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTE 414

Query: 178 PEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYL----HTAIVLTYST-DRLRKWMFI 232
           P+V       C ++  A +Y ++  F WM  EG +L        V+ YS+ +RL KW+  
Sbjct: 415 PKV------LCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMF 468

Query: 233 CIGWGVPFPIIVAWAIG--KLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNI 290
            +G+GVP   +   A     LY   ++CW     G    ++  GP+  +   N +    +
Sbjct: 469 PVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFL--GPVCAIFSANLVLFILV 526

Query: 291 VRILMTKLRASTTSE--TIQYRK--AVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIY 346
             IL  KL +S  SE  TIQ  +  A KAT  L  +LG T+ L  +  G    +  V  Y
Sbjct: 527 FWILKRKL-SSLNSEVSTIQNTRMLAFKATAQLF-ILGCTWCLGLLQVGP---AAQVMAY 581

Query: 347 FNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHR 380
             + + S QGFF+ + YC L+ +V+   +K W R
Sbjct: 582 LFTIINSLQGFFIFLVYCLLSQQVQKQYQK-WFR 614


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score = 89.4 bits (220), Expect = 6e-18
 Identities = 81/297 (27%), Positives = 137/297 (46%), Gaps = 35/297 (11%)

Query: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
           II+++G  ISLV L++A   FL  RSIR     +H +L    +L    +          +
Sbjct: 604 IISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLA-------GI 656

Query: 181 HQS-NVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAI----VLTYSTDRLRKWMFIC-I 234
           H++ N   C ++    +Y  +  FFWM  E   L   +    V+ Y + R  K + IC  
Sbjct: 657 HKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAF 716

Query: 235 GWGVPFPIIV--AWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVR 292
           G+G+P  ++V  A    + Y  + +CW     G    ++  GP+  V++IN + L   + 
Sbjct: 717 GYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFL--GPVCTVIVINSLLLTWTLW 774

Query: 293 ILMTKL-----RASTTSETIQYRKAVKATLVLLPLLGITYML--FFVNPGEDEVSRVVFI 345
           IL  +L       ST  +T   R         L +LG +++L  F + P        V  
Sbjct: 775 ILRQRLSSVNAEVSTLKDT---RLLTFKAFAQLFILGCSWVLGIFQIGPVAG-----VMA 826

Query: 346 YFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAM--SIPTS 400
           Y  + + S QG F+ + +C LN +VR    KRW   + K S +++ +R +  S+P++
Sbjct: 827 YLFTIINSLQGAFIFLIHCLLNGQVREEY-KRWITGKTKPSSQSQTSRILLSSMPSA 882


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 78/276 (28%), Positives = 123/276 (44%), Gaps = 27/276 (9%)

Query: 111  KSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNL-ISAFILRNATW 169
            K  VH  +  +I ++G  ISLV L +    F   R ++  RN IH NL I+ FI      
Sbjct: 826  KDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAE---- 881

Query: 170  FVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKW 229
            F+  + +    +      C +     ++F +  F WM  EG  L+  +V  + ++  RK 
Sbjct: 882  FIFLIGIDKTKYAIA---CPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKK 938

Query: 230  MFICIGWGVPFPII-VAWAIGKLYYDNEK-CWFGKRPGVYTDYIYQGPMILVLLINFIFL 287
             +   G+  P  ++ V+ AI    Y  EK CW       Y  + + GP+  ++L+N IFL
Sbjct: 939  YYYVAGYLFPATVVGVSAAIDYKSYGTEKACWL--HVDNYFIWSFIGPVTFIILLNIIFL 996

Query: 288  FNIVRILMTKLRASTT-----SETIQYRKAVKATLVLLPLLGITYM--LFFVNPGEDEVS 340
               V  L   ++ S T     S     +  V     LL LLG+T+   L F+N       
Sbjct: 997  ---VITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINE-----E 1048

Query: 341  RVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRK 376
             +V  Y  +   +FQG F+ +F+C L  +VR    K
Sbjct: 1049 TIVMAYLFTIFNAFQGVFIFIFHCALQKKVRKEYGK 1084


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 69/262 (26%), Positives = 130/262 (49%), Gaps = 25/262 (9%)

Query: 125  LGHCISLVALLVAFVLFLRL-RSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQS 183
            +G  +S + LL+  ++++ + R IR  R++I  N   + I  NA      L +  +    
Sbjct: 953  VGCGVSSLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNA------LILIGQTQTR 1006

Query: 184  NVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPII 243
            N   C LV A  ++F +++F W+  E    + A+   +  +RL +  F+C+GWG+P  ++
Sbjct: 1007 NKVVCTLVAAFLHFFFLSSFCWVLTEAWQSYMAVT-GHLRNRLIRKRFLCLGWGLP-ALV 1064

Query: 244  VAWAIG----KLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLR 299
            VA ++G    K Y     CW     G+   Y + GP   V+L+N +    +   L++K  
Sbjct: 1065 VAISVGFTKAKGYSTMNYCWLSLEGGLL--YAFVGPAAAVVLVNMVIGILVFNKLVSK-- 1120

Query: 300  ASTTSETIQYRKAVK--ATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSFLESFQ 355
               T + ++ R      ++ V+LPLL +T+M  +  V      + +++F  F    +S +
Sbjct: 1121 DGITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVF----DSLE 1176

Query: 356  GFFVSVFYCFLNSEVRSAIRKR 377
            GF + + +C L  EV+ A++ R
Sbjct: 1177 GFVIVMVHCILRREVQDAVKCR 1198


>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
          Length = 1522

 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 92/347 (26%), Positives = 153/347 (44%), Gaps = 54/347 (15%)

Query: 74   GVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVA 133
            G +   T+  + +CL +      +   + +EI+ E   +     V +I+     C++L+ 
Sbjct: 838  GCKTVLTDASHTKCLCDRLSTFAILAQQPREIIMESSGTP---SVTLIVGSGLSCLALIT 894

Query: 134  LLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTA 193
            L V +    R   IR  R+II  N   + I  N    ++ L    + H  ++  C   TA
Sbjct: 895  LAVVYAALWRY--IRSERSIILINFCLSIISSN----ILILVGQTQTHNKSI--CTTTTA 946

Query: 194  AYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIG---- 249
              ++F + +F W+  E    + A+     T  +RK  F+C+GWG+P  ++VA ++G    
Sbjct: 947  FLHFFFLASFCWVLTEAWQSYMAVTGKIRTRLIRK-RFLCLGWGLP-ALVVATSVGFTRT 1004

Query: 250  KLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINF---IFLFNIV----RILMTKL--RA 300
            K Y  +  CW     G+   Y + GP   V+L+N    I +FN +     IL  KL  RA
Sbjct: 1005 KGYGTDHYCWLSLEGGLL--YAFVGPAAAVVLVNMVIGILVFNKLVSRDGILDKKLKHRA 1062

Query: 301  STTSE-----TIQYRK-------AVKAT------------LVLLPLLGITYMLFFVNPGE 336
               SE     T++  K       A+ AT             V+LPLL +T+M   +    
Sbjct: 1063 GQMSEPHSGLTLKCAKCGVVSTTALSATTASNAMASLWSSCVVLPLLALTWMSAVL--AM 1120

Query: 337  DEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQD 383
             +   ++F    +  +S QGF + + +C L  EV+ A R R    QD
Sbjct: 1121 TDKRSILFQILFAVFDSLQGFVIVMVHCILRREVQDAFRCRLRNCQD 1167


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 71/262 (27%), Positives = 115/262 (43%), Gaps = 19/262 (7%)

Query: 121  IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
            +I ++G  ISLV L +    F  LR ++  RN IH NL     L    + V       E+
Sbjct: 862  VITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEI 921

Query: 181  HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240
                   C +     +YF +  F W+  EG +L+  +V  + ++  R   +   G+  P 
Sbjct: 922  A------CPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPA 975

Query: 241  PII-VAWAIGKLYYDNEK-CWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVR--ILMT 296
             ++ +A AI    Y  EK CW   R   Y  + + GP+  V+++N +FL   +   I  +
Sbjct: 976  LVVGIAAAIDYRSYGTEKACWL--RVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSS 1033

Query: 297  KLRASTTSETIQYRKAVKATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSFLESF 354
             +    +S     +      + LL LLG+T+   L F+N        VV  Y  +   +F
Sbjct: 1034 SVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINK-----ESVVMAYLFTTFNAF 1088

Query: 355  QGFFVSVFYCFLNSEVRSAIRK 376
            QG F+ VF+C L  +V     K
Sbjct: 1089 QGVFIFVFHCALQKKVHKEYSK 1110


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 71/262 (27%), Positives = 115/262 (43%), Gaps = 19/262 (7%)

Query: 121  IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
            +I ++G  ISLV L +    F  LR ++  RN IH NL     L    + V       E+
Sbjct: 857  VITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEI 916

Query: 181  HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240
                   C +     +YF +  F W+  EG +L+  +V  + ++  R   +   G+  P 
Sbjct: 917  A------CPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPA 970

Query: 241  PII-VAWAIGKLYYDNEK-CWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVR--ILMT 296
             ++ +A AI    Y  EK CW   R   Y  + + GP+  V+++N +FL   +   I  +
Sbjct: 971  LVVGIAAAIDYRSYGTEKACWL--RVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSS 1028

Query: 297  KLRASTTSETIQYRKAVKATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSFLESF 354
             +    +S     +      + LL LLG+T+   L F+N        VV  Y  +   +F
Sbjct: 1029 SVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINK-----ESVVMAYLFTTFNAF 1083

Query: 355  QGFFVSVFYCFLNSEVRSAIRK 376
            QG F+ VF+C L  +V     K
Sbjct: 1084 QGVFIFVFHCALQKKVHKEYSK 1105


>gi|23397681 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform a [Homo sapiens]
          Length = 823

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 71/270 (26%), Positives = 117/270 (43%), Gaps = 24/270 (8%)

Query: 118 VAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMS 177
           V  +I Y+G  +SL+ LL+A + FL  ++I+     +H  L     L +  + V      
Sbjct: 535 VLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTG 594

Query: 178 PEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYL----HTAIVLTYST-DRLRKWMFI 232
            +V       C ++    +Y ++    WM  E  YL        V+ YS+ +R  K +  
Sbjct: 595 HKV------LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMF 648

Query: 233 CIGWGVPFPIIVAWAIGK--LYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNI 290
            +G+GVP   +   A  +  LY    +CW     G    ++  GP+  +  +N +     
Sbjct: 649 PVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFL--GPVCAIFSVNLVLFLVT 706

Query: 291 VRILMTKLRASTTSETIQYRK----AVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIY 346
           + IL  +L +S  SE    R     A KAT  L  +LG T+ L  +  G    +  V  Y
Sbjct: 707 LWILKNRL-SSLNSEVSTLRNTRMLAFKATAQLF-ILGCTWCLGILQVGP---AARVMAY 761

Query: 347 FNSFLESFQGFFVSVFYCFLNSEVRSAIRK 376
             + + S QG F+ + YC L+ +VR    K
Sbjct: 762 LFTIINSLQGVFIFLVYCLLSQQVREQYGK 791


>gi|23397693 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform g [Homo sapiens]
          Length = 719

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 71/270 (26%), Positives = 117/270 (43%), Gaps = 24/270 (8%)

Query: 118 VAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMS 177
           V  +I Y+G  +SL+ LL+A + FL  ++I+     +H  L     L +  + V      
Sbjct: 431 VLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTG 490

Query: 178 PEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYL----HTAIVLTYST-DRLRKWMFI 232
            +V       C ++    +Y ++    WM  E  YL        V+ YS+ +R  K +  
Sbjct: 491 HKV------LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMF 544

Query: 233 CIGWGVPFPIIVAWAIGK--LYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNI 290
            +G+GVP   +   A  +  LY    +CW     G    ++  GP+  +  +N +     
Sbjct: 545 PVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFL--GPVCAIFSVNLVLFLVT 602

Query: 291 VRILMTKLRASTTSETIQYRK----AVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIY 346
           + IL  +L +S  SE    R     A KAT  L  +LG T+ L  +  G    +  V  Y
Sbjct: 603 LWILKNRL-SSLNSEVSTLRNTRMLAFKATAQLF-ILGCTWCLGILQVGP---AARVMAY 657

Query: 347 FNSFLESFQGFFVSVFYCFLNSEVRSAIRK 376
             + + S QG F+ + YC L+ +VR    K
Sbjct: 658 LFTIINSLQGVFIFLVYCLLSQQVREQYGK 687


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.140    0.457 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,961,619
Number of Sequences: 37866
Number of extensions: 623896
Number of successful extensions: 1922
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 1671
Number of HSP's gapped (non-prelim): 126
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.