Search of human proteins with 19913428

Search of human proteins with 19913428

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19913428 vacuolar H+ATPase B2 [Homo sapiens]
         (511 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19913428 vacuolar H+ATPase B2 [Homo sapiens]                      1015   0.0  
gi|19913426 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subu...   867   0.0  
gi|32189394 mitochondrial ATP synthase beta subunit precursor [H...   117   2e-26
gi|50345984 ATP synthase, H+ transporting, mitochondrial F1 comp...   102   6e-22
gi|4757810 ATP synthase, H+ transporting, mitochondrial F1 compl...   102   6e-22
gi|19913424 ATPase, H+ transporting, lysosomal V1 subunit A [Hom...    84   4e-16
gi|214010149 gamma-glutamyl carboxylase isoform 2 [Homo sapiens]       29   8.9  
gi|21361163 gamma-glutamyl carboxylase isoform 1 [Homo sapiens]        29   8.9  
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]             29   8.9  

>gi|19913428 vacuolar H+ATPase B2 [Homo sapiens]
          Length = 511

 Score = 1015 bits (2625), Expect = 0.0
 Identities = 511/511 (100%), Positives = 511/511 (100%)

Query: 1   MALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVIL 60
           MALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVIL
Sbjct: 1   MALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVIL 60

Query: 61  DHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILR 120
           DHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILR
Sbjct: 61  DHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILR 120

Query: 121 TPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGM 180
           TPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGM
Sbjct: 121 TPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGM 180

Query: 181 NSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMET 240
           NSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMET
Sbjct: 181 NSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMET 240

Query: 241 ARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDM 300
           ARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDM
Sbjct: 241 ARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDM 300

Query: 301 SSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDD 360
           SSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDD
Sbjct: 301 SSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDD 360

Query: 361 ITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSN 420
           ITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSN
Sbjct: 361 ITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSN 420

Query: 421 QLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIG 480
           QLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIG
Sbjct: 421 QLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIG 480

Query: 481 WQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH 511
           WQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH
Sbjct: 481 WQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH 511


>gi|19913426 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit
           B1 [Homo sapiens]
          Length = 513

 Score =  867 bits (2239), Expect = 0.0
 Identities = 428/482 (88%), Positives = 458/482 (95%)

Query: 28  AREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVL 87
           ARE   AV+RNY++ PR+TY+TV  VNGPLV+LD VKF +YAEIVH TLPDGT+RSGQVL
Sbjct: 22  AREHMQAVTRNYITHPRVTYRTVCSVNGPLVVLDRVKFAQYAEIVHFTLPDGTQRSGQVL 81

Query: 88  EVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLA 147
           EV+G+KA+VQVFEGTSGIDA+KT+CEFTGDILRTPVSEDMLGRVFNGSGKPID+GPVV+A
Sbjct: 82  EVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMA 141

Query: 148 EDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQIC 207
           EDFLDI GQPINP  RIYPEEMIQTGIS ID MNSIARGQKIPIFSAAGLPHNEIAAQIC
Sbjct: 142 EDFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQIC 201

Query: 208 RQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDP 267
           RQAGLVKKSK V+DY ++NFAIVFAAMGVNMETARFFKSDFE+NG+M NVCLFLNLANDP
Sbjct: 202 RQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDP 261

Query: 268 TIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYM 327
           TIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYM
Sbjct: 262 TIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYM 321

Query: 328 YTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQ 387
           YTDLATIYERAGRVEGR GSITQIPILTMPNDDITHPIPDLTG+ITEGQIYVDRQLHNRQ
Sbjct: 322 YTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQ 381

Query: 388 IYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSD 447
           IYPPINVLPSLSRLMKSAIGEGMTRKDH DVSNQLYACYAIGKDVQAMKAVVGEEALTS+
Sbjct: 382 IYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSE 441

Query: 448 DLLYLEFLQKFERNFIAQGPYENRTVFETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRD 507
           DLLYLEFLQKFE+NFI QGPYENR+VFE+LD+GW+LLRIFPKEMLKRIPQ+ + EFY R+
Sbjct: 442 DLLYLEFLQKFEKNFINQGPYENRSVFESLDLGWKLLRIFPKEMLKRIPQAVIDEFYSRE 501

Query: 508 SA 509
            A
Sbjct: 502 GA 503


>gi|32189394 mitochondrial ATP synthase beta subunit precursor [Homo
           sapiens]
          Length = 529

 Score =  117 bits (294), Expect = 2e-26
 Identities = 118/481 (24%), Positives = 209/481 (43%), Gaps = 35/481 (7%)

Query: 8   GIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPR 67
           G +    P   +P     + A   A+   R+Y +Q   + K  +     + ++  V   +
Sbjct: 15  GALRRLTPSASLPPAQLLLRAAPTAVHPVRDYAAQTSPSPKAGAATGRIVAVIGAVVDVQ 74

Query: 68  YAE----IVHLTLPDGTKRSGQVLEVS---GSKAVVQV-FEGTSGIDAKKTSCEFTGDIL 119
           + E    I++     G + +  VLEV+   G   V  +  +GT G+   +   + +G  +
Sbjct: 75  FDEGLPPILNALEVQG-RETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLD-SGAPI 132

Query: 120 RTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDG 179
           + PV  + LGR+ N  G+PID    +  + F  I  +          +E++ TGI  +D 
Sbjct: 133 KIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFMEMSVEQEILVTGIKVVDL 192

Query: 180 MNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNME 239
           +   A+G KI +F  AG+    +  ++         +K    YS      VFA +G    
Sbjct: 193 LAPYAKGGKIGLFGGAGVGKTVLIMELINNV-----AKAHGGYS------VFAGVGERTR 241

Query: 240 TARFFKSDFEENGSMD------NVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHV 293
                  +  E+G ++       V L     N+P   R       LT AE+   Q  + V
Sbjct: 242 EGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDV 301

Query: 294 LVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPI 353
           L+ + ++  + +A  EVSA    +P   G+   + TD+ T+ ER      + GSIT +  
Sbjct: 302 LLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTT--KKGSITSVQA 359

Query: 354 LTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRK 413
           + +P DD+T P P  T    +    + R +    IYP ++ L S SR+M   I       
Sbjct: 360 IYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNI----VGS 415

Query: 414 DHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTV 473
           +H DV+  +       K +Q + A++G + L+ +D L +   +K +R F++Q P++   V
Sbjct: 416 EHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQR-FLSQ-PFQVAEV 473

Query: 474 F 474
           F
Sbjct: 474 F 474


>gi|50345984 ATP synthase, H+ transporting, mitochondrial F1
           complex, alpha subunit precursor [Homo sapiens]
          Length = 553

 Score =  102 bits (255), Expect = 6e-22
 Identities = 87/296 (29%), Positives = 139/296 (46%), Gaps = 13/296 (4%)

Query: 115 TGDILRTPVSEDMLGRVFNGSGKPID-RGPV-VLAEDFLDIMGQPINPQCRIYPEEMIQT 172
           TG I+  PV E++LGRV +  G  ID +GP+       + +    I P  RI   E +QT
Sbjct: 134 TGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKTRRRVGLKAPGIIP--RISVREPMQT 191

Query: 173 GISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQ-ICRQAGLVKKSKDVVDYSEENFAIVF 231
           GI A+D +  I RGQ+  I          IA   I  Q    K+  D  D  ++ + I +
Sbjct: 192 GIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQ----KRFNDGSDEKKKLYCI-Y 246

Query: 232 AAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEK 291
            A+G    T         +  +M    +    A+D    + + P    +  E+      K
Sbjct: 247 VAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDN-GK 305

Query: 292 HVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGR--NGSIT 349
           H L+I  D+S  A A R++S      PGR  +PG ++   + + ERA ++      GS+T
Sbjct: 306 HALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLT 365

Query: 350 QIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSA 405
            +P++     D++  IP     IT+GQI+++ +L  + I P INV  S+SR+  +A
Sbjct: 366 ALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAA 421


>gi|4757810 ATP synthase, H+ transporting, mitochondrial F1 complex,
           alpha subunit precursor [Homo sapiens]
          Length = 553

 Score =  102 bits (255), Expect = 6e-22
 Identities = 87/296 (29%), Positives = 139/296 (46%), Gaps = 13/296 (4%)

Query: 115 TGDILRTPVSEDMLGRVFNGSGKPID-RGPV-VLAEDFLDIMGQPINPQCRIYPEEMIQT 172
           TG I+  PV E++LGRV +  G  ID +GP+       + +    I P  RI   E +QT
Sbjct: 134 TGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKTRRRVGLKAPGIIP--RISVREPMQT 191

Query: 173 GISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQ-ICRQAGLVKKSKDVVDYSEENFAIVF 231
           GI A+D +  I RGQ+  I          IA   I  Q    K+  D  D  ++ + I +
Sbjct: 192 GIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQ----KRFNDGSDEKKKLYCI-Y 246

Query: 232 AAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEK 291
            A+G    T         +  +M    +    A+D    + + P    +  E+      K
Sbjct: 247 VAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDN-GK 305

Query: 292 HVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGR--NGSIT 349
           H L+I  D+S  A A R++S      PGR  +PG ++   + + ERA ++      GS+T
Sbjct: 306 HALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLT 365

Query: 350 QIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSA 405
            +P++     D++  IP     IT+GQI+++ +L  + I P INV  S+SR+  +A
Sbjct: 366 ALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAA 421


>gi|19913424 ATPase, H+ transporting, lysosomal V1 subunit A [Homo
           sapiens]
          Length = 617

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 61/222 (27%), Positives = 107/222 (48%), Gaps = 9/222 (4%)

Query: 254 MDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAA 313
           M    L  N +N P   R  +    +T +E+       HV ++    S +AEALRE+S  
Sbjct: 306 MKRTALVANTSNMPVAAREASIYTGITLSEYFR-DMGYHVSMMADSTSRWAEALREISGR 364

Query: 314 REEVPGRRGFPGYMYTDLATIYERAGRVE-----GRNGSITQIPILTMPNDDITHPIPDL 368
             E+P   G+P Y+   LA+ YERAGRV+      R GS++ +  ++ P  D + P+   
Sbjct: 365 LAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSA 424

Query: 369 TGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTR--KDHADVSNQLYACY 426
           T  I +    +D++L  R+ +P +N L S S+ M+ A+ E   +   +   +  +     
Sbjct: 425 TLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMR-ALDEYYDKHFTEFVPLRTKAKEIL 483

Query: 427 AIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPY 468
              +D+  +  +VG+ +L   D + LE  +  + +F+ Q  Y
Sbjct: 484 QEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGY 525



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 46  TYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGI 105
           T+  V GV+GP+V    +      E+V +     ++  G+++ + G  A +QV+E TSG+
Sbjct: 17  TFGYVHGVSGPVVTACDMAGAAMYELVRV---GHSELVGEIIRLEGDMATIQVYEETSGV 73

Query: 106 DAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPI 139
                    TG  L   +   ++G +F+G  +P+
Sbjct: 74  SVGDPVLR-TGKPLSVELGPGIMGAIFDGIQRPL 106


>gi|214010149 gamma-glutamyl carboxylase isoform 2 [Homo sapiens]
          Length = 701

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 19/64 (29%), Positives = 32/64 (50%), Gaps = 3/64 (4%)

Query: 265 NDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAARE---EVPGRR 321
           ND   +RI  PR+ +  A +  +Q    V  +L D+S +   L+E+ ++ +   EV    
Sbjct: 417 NDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPLLMDLSPWRAKLQEIKSSLDNHTEVVFIA 476

Query: 322 GFPG 325
            FPG
Sbjct: 477 DFPG 480


>gi|21361163 gamma-glutamyl carboxylase isoform 1 [Homo sapiens]
          Length = 758

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 19/64 (29%), Positives = 32/64 (50%), Gaps = 3/64 (4%)

Query: 265 NDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAARE---EVPGRR 321
           ND   +RI  PR+ +  A +  +Q    V  +L D+S +   L+E+ ++ +   EV    
Sbjct: 474 NDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPLLMDLSPWRAKLQEIKSSLDNHTEVVFIA 533

Query: 322 GFPG 325
            FPG
Sbjct: 534 DFPG 537


>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
          Length = 4981

 Score = 29.3 bits (64), Expect = 8.9
 Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 6/85 (7%)

Query: 290  EKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGR----VEGRN 345
            E  VL+ + + S+Y     ++   +       G  G +  ++  +Y   G     + G+N
Sbjct: 4255 ENGVLIHIQESSNYTTV--KIKNGKVYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKN 4312

Query: 346  GSITQIPILTMPNDDITHPIPDLTG 370
            G+ T + +  + N DI HP  D  G
Sbjct: 4313 GTATVLSVDRIYNRDIIHPTQDFGG 4337


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,809,281
Number of Sequences: 37866
Number of extensions: 847156
Number of successful extensions: 1752
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1735
Number of HSP's gapped (non-prelim): 10
length of query: 511
length of database: 18,247,518
effective HSP length: 107
effective length of query: 404
effective length of database: 14,195,856
effective search space: 5735125824
effective search space used: 5735125824
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.