Guide to the Human Genome
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Search of human proteins with 197927278

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197927278 Der1-like domain family, member 1 isoform b [Homo
sapiens]
         (231 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197927278 Der1-like domain family, member 1 isoform b [Homo s...   492   e-139
gi|13236516 Der1-like domain family, member 1 isoform a [Homo sa...   480   e-136
gi|31455614 Der1-like domain family, member 2 [Homo sapiens]          120   8e-28
gi|209364542 derlin 3 isoform 1 [Homo sapiens]                        116   1e-26
gi|50845411 derlin 3 isoform 2 [Homo sapiens]                         116   1e-26
gi|50845409 derlin 3 isoform 3 [Homo sapiens]                         116   1e-26
gi|239753508 PREDICTED: hypothetical protein [Homo sapiens]            28   8.7  
gi|239748157 PREDICTED: hypothetical protein [Homo sapiens]            28   8.7  
gi|239742055 PREDICTED: hypothetical protein XP_002342401 [Homo ...    28   8.7  

>gi|197927278 Der1-like domain family, member 1 isoform b [Homo
           sapiens]
          Length = 231

 Score =  492 bits (1266), Expect = e-139
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 1   MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF 60
           MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF
Sbjct: 1   MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF 60

Query: 61  YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL 120
           YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL
Sbjct: 61  YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL 120

Query: 121 LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSYPMDLGGRNFL 180
           LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSYPMDLGGRNFL
Sbjct: 121 LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSYPMDLGGRNFL 180

Query: 181 STPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGDQ 231
           STPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGDQ
Sbjct: 181 STPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGDQ 231


>gi|13236516 Der1-like domain family, member 1 isoform a [Homo
           sapiens]
          Length = 251

 Score =  480 bits (1235), Expect = e-136
 Identities = 231/251 (92%), Positives = 231/251 (92%), Gaps = 20/251 (7%)

Query: 1   MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF 60
           MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF
Sbjct: 1   MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF 60

Query: 61  YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL 120
           YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL
Sbjct: 61  YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL 120

Query: 121 LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGS----------- 169
           LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGS           
Sbjct: 121 LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVG 180

Query: 170 ---------YPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRH 220
                    YPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRH
Sbjct: 181 HLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRH 240

Query: 221 NWGQGFRLGDQ 231
           NWGQGFRLGDQ
Sbjct: 241 NWGQGFRLGDQ 251


>gi|31455614 Der1-like domain family, member 2 [Homo sapiens]
          Length = 239

 Score =  120 bits (302), Expect = 8e-28
 Identities = 77/233 (33%), Positives = 120/233 (51%), Gaps = 15/233 (6%)

Query: 8   FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67
           +  IP ++R +  A V      +L LI+P  L+  PE     FQIWR IT   +F  GP 
Sbjct: 10  YLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFF--GP- 66

Query: 68  TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127
            GF +L N+ FLY+Y   LE G+F GR AD++FM LF    + + GL + +  L     +
Sbjct: 67  VGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTI 126

Query: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSYPMDLGGRNFLSTPQFLY 187
            ++YVW++ N  + ++F+    F+A +LPWV++GF+ ++G S  +DL G        FL 
Sbjct: 127 MLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLE 186

Query: 188 RWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHN-----------WGQGFRLG 229
              P++ GG+      P+ ++   D       +N           WG+G RLG
Sbjct: 187 DVFPNQPGGIRILKT-PSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLG 238


>gi|209364542 derlin 3 isoform 1 [Homo sapiens]
          Length = 239

 Score =  116 bits (291), Expect = 1e-26
 Identities = 65/189 (34%), Positives = 106/189 (56%), Gaps = 3/189 (1%)

Query: 8   FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67
           F  +PA+TR + AA V      +L L+SP  L+  P     +FQ+WR +T   +F  GP 
Sbjct: 10  FLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFF--GP- 66

Query: 68  TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127
            GF +  N+ F+++Y   LE G+F GR AD++FM LF  + + + GL   +  L   L+ 
Sbjct: 67  LGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFLGQALMA 126

Query: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSYPMDLGGRNFLSTPQFLY 187
            ++YVW++ +  + V+F+    F+A +LPW ++GF+ ++G S  +DL G        FL 
Sbjct: 127 MLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGHIYYFLE 186

Query: 188 RWLPSRRGG 196
              P++ GG
Sbjct: 187 DVFPNQPGG 195


>gi|50845411 derlin 3 isoform 2 [Homo sapiens]
          Length = 235

 Score =  116 bits (291), Expect = 1e-26
 Identities = 65/189 (34%), Positives = 106/189 (56%), Gaps = 3/189 (1%)

Query: 8   FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67
           F  +PA+TR + AA V      +L L+SP  L+  P     +FQ+WR +T   +F  GP 
Sbjct: 10  FLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFF--GP- 66

Query: 68  TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127
            GF +  N+ F+++Y   LE G+F GR AD++FM LF  + + + GL   +  L   L+ 
Sbjct: 67  LGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFLGQALMA 126

Query: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSYPMDLGGRNFLSTPQFLY 187
            ++YVW++ +  + V+F+    F+A +LPW ++GF+ ++G S  +DL G        FL 
Sbjct: 127 MLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGHIYYFLE 186

Query: 188 RWLPSRRGG 196
              P++ GG
Sbjct: 187 DVFPNQPGG 195


>gi|50845409 derlin 3 isoform 3 [Homo sapiens]
          Length = 205

 Score =  116 bits (291), Expect = 1e-26
 Identities = 65/189 (34%), Positives = 106/189 (56%), Gaps = 3/189 (1%)

Query: 8   FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67
           F  +PA+TR + AA V      +L L+SP  L+  P     +FQ+WR +T   +F  GP 
Sbjct: 10  FLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFF--GP- 66

Query: 68  TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127
            GF +  N+ F+++Y   LE G+F GR AD++FM LF  + + + GL   +  L   L+ 
Sbjct: 67  LGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFLGQALMA 126

Query: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSYPMDLGGRNFLSTPQFLY 187
            ++YVW++ +  + V+F+    F+A +LPW ++GF+ ++G S  +DL G        FL 
Sbjct: 127 MLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGHIYYFLE 186

Query: 188 RWLPSRRGG 196
              P++ GG
Sbjct: 187 DVFPNQPGG 195


>gi|239753508 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 123

 Score = 27.7 bits (60), Expect = 8.7
 Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 11/42 (26%)

Query: 189 WLPSRRGGVSGFGVPPASMRRAAD---QNGGGGRHNWGQGFR 227
           W P  RGG +G        RR A     NGGGGR  W    R
Sbjct: 11  WRPGPRGGRAG--------RREAGGPGHNGGGGRARWAAAAR 44


>gi|239748157 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 128

 Score = 27.7 bits (60), Expect = 8.7
 Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 11/42 (26%)

Query: 189 WLPSRRGGVSGFGVPPASMRRAAD---QNGGGGRHNWGQGFR 227
           W P  RGG +G        RR A     NGGGGR  W    R
Sbjct: 11  WRPGPRGGRAG--------RREAGGPGHNGGGGRARWAAAAR 44


>gi|239742055 PREDICTED: hypothetical protein XP_002342401 [Homo
           sapiens]
          Length = 128

 Score = 27.7 bits (60), Expect = 8.7
 Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 11/42 (26%)

Query: 189 WLPSRRGGVSGFGVPPASMRRAAD---QNGGGGRHNWGQGFR 227
           W P  RGG +G        RR A     NGGGGR  W    R
Sbjct: 11  WRPGPRGGRAG--------RREAGGPGHNGGGGRARWAAAAR 44


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.148    0.510 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,291,559
Number of Sequences: 37866
Number of extensions: 436665
Number of successful extensions: 1013
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 999
Number of HSP's gapped (non-prelim): 12
length of query: 231
length of database: 18,247,518
effective HSP length: 99
effective length of query: 132
effective length of database: 14,498,784
effective search space: 1913839488
effective search space used: 1913839488
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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