Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 19743871

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19743871 Fc alpha receptor isoform i precursor [Homo
sapiens]
         (239 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19743871 Fc alpha receptor isoform i precursor [Homo sapiens]      504   e-143
gi|4503673 Fc alpha receptor isoform a precursor [Homo sapiens]       448   e-126
gi|19743861 Fc alpha receptor isoform d [Homo sapiens]                416   e-117
gi|19743857 Fc alpha receptor isoform b precursor [Homo sapiens]      400   e-112
gi|19743869 Fc alpha receptor isoform h [Homo sapiens]                368   e-102
gi|19743865 Fc alpha receptor isoform f [Homo sapiens]                362   e-100
gi|19743859 Fc alpha receptor isoform c precursor [Homo sapiens]      248   3e-66
gi|19743863 Fc alpha receptor isoform e [Homo sapiens]                216   1e-56
gi|19743867 Fc alpha receptor isoform g [Homo sapiens]                205   2e-53
gi|143770741 glycoprotein VI (platelet) isoform 1 [Homo sapiens]      139   3e-33
gi|143770755 glycoprotein VI (platelet) isoform 2 [Homo sapiens]      139   3e-33
gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A...   133   2e-31
gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A (...   133   2e-31
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B...   128   4e-30
gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B...   128   4e-30
gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B...   128   4e-30
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B...   128   4e-30
gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A...   122   3e-28
gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m...   122   3e-28
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B...   122   4e-28
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B...   122   4e-28
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B...   120   1e-27
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B...   120   1e-27
gi|224586788 natural cytotoxicity triggering receptor 1 isoform ...   119   2e-27
gi|224586786 natural cytotoxicity triggering receptor 1 isoform ...   119   2e-27
gi|4758692 natural cytotoxicity triggering receptor 1 isoform a ...   119   2e-27
gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A ...   118   4e-27
gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B...   118   5e-27
gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B...   118   5e-27
gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A (...   114   7e-26

>gi|19743871 Fc alpha receptor isoform i precursor [Homo sapiens]
          Length = 239

 Score =  504 bits (1298), Expect = e-143
 Identities = 239/239 (100%), Positives = 239/239 (100%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL
Sbjct: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
           MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT
Sbjct: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 180
           GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL
Sbjct: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 180

Query: 181 GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRYRPVQPCVWVGCPGPCHRAGI 239
           GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRYRPVQPCVWVGCPGPCHRAGI
Sbjct: 181 GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRYRPVQPCVWVGCPGPCHRAGI 239


>gi|4503673 Fc alpha receptor isoform a precursor [Homo sapiens]
          Length = 287

 Score =  448 bits (1153), Expect = e-126
 Identities = 216/216 (100%), Positives = 216/216 (100%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL
Sbjct: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
           MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT
Sbjct: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 180
           GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL
Sbjct: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 180

Query: 181 GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVT 216
           GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVT
Sbjct: 181 GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVT 216



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 7/103 (6%)

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPF-DRFSLAKEG---ELSLPQHQSGEHPA 176
           G +  PF+SA    V+    ++ + C +    +  +  + K     E+        E   
Sbjct: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNETDP 83

Query: 177 NFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
            F +  +D N +G Y+C   Y    Y + + S+ LELVVTG Y
Sbjct: 84  EFVIDHMDANKAGRYQCQ--YRIGHYRFRY-SDTLELVVTGLY 123


>gi|19743861 Fc alpha receptor isoform d [Homo sapiens]
          Length = 275

 Score =  416 bits (1070), Expect = e-117
 Identities = 204/216 (94%), Positives = 204/216 (94%), Gaps = 12/216 (5%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           MDPKQTTLLCL            GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL
Sbjct: 1   MDPKQTTLLCL------------GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 48

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
           MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT
Sbjct: 49  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 108

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 180
           GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL
Sbjct: 109 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 168

Query: 181 GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVT 216
           GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVT
Sbjct: 169 GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVT 204



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 7/107 (6%)

Query: 117 LVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPF-DRFSLAKEG---ELSLPQHQSG 172
           L+  G +  PF+SA    V+    ++ + C +    +  +  + K     E+        
Sbjct: 8   LLCLGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWN 67

Query: 173 EHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
           E    F +  +D N +G Y+C   Y    Y + + S+ LELVVTG Y
Sbjct: 68  ETDPEFVIDHMDANKAGRYQCQ--YRIGHYRFRY-SDTLELVVTGLY 111


>gi|19743857 Fc alpha receptor isoform b precursor [Homo sapiens]
          Length = 265

 Score =  400 bits (1028), Expect = e-112
 Identities = 194/194 (100%), Positives = 194/194 (100%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL
Sbjct: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
           MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT
Sbjct: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 180
           GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL
Sbjct: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 180

Query: 181 GPVDLNVSGIYRCY 194
           GPVDLNVSGIYRCY
Sbjct: 181 GPVDLNVSGIYRCY 194



 Score = 29.6 bits (65), Expect = 2.4
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 7/103 (6%)

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPF-DRFSLAKEG---ELSLPQHQSGEHPA 176
           G +  PF+SA    V+    ++ + C +    +  +  + K     E+        E   
Sbjct: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNETDP 83

Query: 177 NFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
            F +  +D N +G Y+C   Y    Y + + S+ LELVVTG Y
Sbjct: 84  EFVIDHMDANKAGRYQCQ--YRIGHYRFRY-SDTLELVVTGLY 123


>gi|19743869 Fc alpha receptor isoform h [Homo sapiens]
          Length = 253

 Score =  368 bits (945), Expect = e-102
 Identities = 182/194 (93%), Positives = 182/194 (93%), Gaps = 12/194 (6%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           MDPKQTTLLCL            GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL
Sbjct: 1   MDPKQTTLLCL------------GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 48

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
           MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT
Sbjct: 49  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 108

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 180
           GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL
Sbjct: 109 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 168

Query: 181 GPVDLNVSGIYRCY 194
           GPVDLNVSGIYRCY
Sbjct: 169 GPVDLNVSGIYRCY 182



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 7/107 (6%)

Query: 117 LVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPF-DRFSLAKEG---ELSLPQHQSG 172
           L+  G +  PF+SA    V+    ++ + C +    +  +  + K     E+        
Sbjct: 8   LLCLGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWN 67

Query: 173 EHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
           E    F +  +D N +G Y+C   Y    Y + + S+ LELVVTG Y
Sbjct: 68  ETDPEFVIDHMDANKAGRYQCQ--YRIGHYRFRY-SDTLELVVTGLY 111


>gi|19743865 Fc alpha receptor isoform f [Homo sapiens]
          Length = 209

 Score =  362 bits (930), Expect = e-100
 Identities = 180/194 (92%), Positives = 181/194 (93%), Gaps = 12/194 (6%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           MDPKQTTLLCL            GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL
Sbjct: 1   MDPKQTTLLCL------------GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 48

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
           MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT
Sbjct: 49  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 108

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 180
           GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL
Sbjct: 109 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 168

Query: 181 GPVDLNVSGIYRCY 194
           GPVDLNVSGIYR +
Sbjct: 169 GPVDLNVSGIYRLH 182



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 7/107 (6%)

Query: 117 LVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPF-DRFSLAKEG---ELSLPQHQSG 172
           L+  G +  PF+SA    V+    ++ + C +    +  +  + K     E+        
Sbjct: 8   LLCLGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWN 67

Query: 173 EHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
           E    F +  +D N +G Y+C   Y    Y + + S+ LELVVTG Y
Sbjct: 68  ETDPEFVIDHMDANKAGRYQCQ--YRIGHYRFRY-SDTLELVVTGLY 111


>gi|19743859 Fc alpha receptor isoform c precursor [Homo sapiens]
          Length = 191

 Score =  248 bits (634), Expect = 3e-66
 Identities = 120/120 (100%), Positives = 120/120 (100%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL
Sbjct: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
           MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT
Sbjct: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120


>gi|19743863 Fc alpha receptor isoform e [Homo sapiens]
          Length = 179

 Score =  216 bits (551), Expect = 1e-56
 Identities = 108/120 (90%), Positives = 108/120 (90%), Gaps = 12/120 (10%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           MDPKQTTLLCL            GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL
Sbjct: 1   MDPKQTTLLCL------------GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 48

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
           MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT
Sbjct: 49  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 108


>gi|19743867 Fc alpha receptor isoform g [Homo sapiens]
          Length = 178

 Score =  205 bits (522), Expect = 2e-53
 Identities = 97/100 (97%), Positives = 98/100 (98%)

Query: 117 LVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPA 176
           L+  GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPA
Sbjct: 8   LLCLGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPA 67

Query: 177 NFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVT 216
           NFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVT
Sbjct: 68  NFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVT 107



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 36/123 (29%), Positives = 54/123 (43%), Gaps = 19/123 (15%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           MDPKQTTLLCL            G +  PF+SA    V+    ++ + C +    +  + 
Sbjct: 1   MDPKQTTLLCL------------GLYGKPFLSADRGLVLMPGENISLTCSSAHIPF-DRF 47

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQ--YRIGHYRFRY-SDTLEL 117
            + K     E+        E    F +  +D N +G Y+C   Y    Y + + S+ LEL
Sbjct: 48  SLAKEG---ELSLPQHQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALEL 104

Query: 118 VVT 120
           VVT
Sbjct: 105 VVT 107


>gi|143770741 glycoprotein VI (platelet) isoform 1 [Homo sapiens]
          Length = 620

 Score =  139 bits (349), Expect = 3e-33
 Identities = 84/217 (38%), Positives = 119/217 (54%), Gaps = 13/217 (5%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T L CL LCLG R+ AQ G  P P + A  S ++PL+  V ++CQ      L +L
Sbjct: 1   MSPSPTALFCLGLCLG-RVPAQSGPLPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRL 59

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
             + +S Y++                I  M  + AGRY+C Y+ G      SD LELV T
Sbjct: 60  EKLSSSRYQD-----------QAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVAT 108

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 180
           G++ KP LSA  G  +  G +++L C + +  FD+F+L KEG+ +  ++    + A+F +
Sbjct: 109 GVFAKPSLSAQPGPAVSSGGDVTLQCQTRY-GFDQFALYKEGDPAPYKNPERWYRASFPI 167

Query: 181 GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
             V    SG YRCY + +R PYLWS PS+ LELVVTG
Sbjct: 168 ITVTAAHSGTYRCYSFSSRDPYLWSAPSDPLELVVTG 204


>gi|143770755 glycoprotein VI (platelet) isoform 2 [Homo sapiens]
          Length = 339

 Score =  139 bits (349), Expect = 3e-33
 Identities = 84/217 (38%), Positives = 119/217 (54%), Gaps = 13/217 (5%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T L CL LCLG R+ AQ G  P P + A  S ++PL+  V ++CQ      L +L
Sbjct: 1   MSPSPTALFCLGLCLG-RVPAQSGPLPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRL 59

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
             + +S Y++                I  M  + AGRY+C Y+ G      SD LELV T
Sbjct: 60  EKLSSSRYQD-----------QAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVAT 108

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSL 180
           G++ KP LSA  G  +  G +++L C + +  FD+F+L KEG+ +  ++    + A+F +
Sbjct: 109 GVFAKPSLSAQPGPAVSSGGDVTLQCQTRY-GFDQFALYKEGDPAPYKNPERWYRASFPI 167

Query: 181 GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
             V    SG YRCY + +R PYLWS PS+ LELVVTG
Sbjct: 168 ITVTAAHSGTYRCYSFSSRDPYLWSAPSDPLELVVTG 204


>gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A
           (with TM domain), member 2 isoform a [Homo sapiens]
          Length = 483

 Score =  133 bits (334), Expect = 2e-31
 Identities = 88/223 (39%), Positives = 116/223 (52%), Gaps = 10/223 (4%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T L+CL L LG R   Q G  P P + A+   VI     V ++CQ   +A   + 
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQA--EEY 58

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
            + + +      RR++   +   +F I  +    AGRY CQY   ++   YSD LELVVT
Sbjct: 59  HLYRENKSASWVRRIQEPGKNG-QFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVT 117

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQ------HQSGEH 174
           G Y KP LSA    V+  G N++L C S  + FD F L KEGE   PQ      H  G  
Sbjct: 118 GAYSKPTLSALPSPVVTLGGNVTLQCVS-QVAFDGFILCKEGEDEHPQRLNSHSHARGWS 176

Query: 175 PANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
            A FS+GPV  +    YRCY + + SPY+WS PS+ LEL+V G
Sbjct: 177 WAIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPG 219



 Score = 96.3 bits (238), Expect = 2e-20
 Identities = 75/219 (34%), Positives = 114/219 (52%), Gaps = 24/219 (10%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGR-----RLKFW 78
           G +  P +SA  SPV+ L G+V +QC  + +      ++ K        R       + W
Sbjct: 118 GAYSKPTLSALPSPVVTLGGNVTLQC--VSQVAFDGFILCKEGEDEHPQRLNSHSHARGW 175

Query: 79  NETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYS---DTLELVVTGLYGKPFLSADRGLV 135
           +     F +  +  ++   Y+C     +  + +S   D LEL+V G+  KP LS   G +
Sbjct: 176 SWAI--FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPM 233

Query: 136 LMPGENISLTCSSAHIPFDRFSLAKEGE---LSLP--QHQSGEHPANFSLGPVDLNVSGI 190
           + PGE+++L C S  + +DRF L KEGE   L  P  Q Q+G   ANF+LGPV  +  G 
Sbjct: 234 VAPGESLTLQCVS-DVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQ 292

Query: 191 YRCYGWYNRSPYLWSFPSNALELVVTGRY--RP---VQP 224
           YRCY  +N S   WS PS+ L++++TG++  RP   VQP
Sbjct: 293 YRCYSAHNLSSE-WSAPSDPLDILITGQFYDRPSLSVQP 330



 Score = 80.9 bits (198), Expect = 9e-16
 Identities = 59/207 (28%), Positives = 101/207 (48%), Gaps = 15/207 (7%)

Query: 29  PFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNE---TDPEF 85
           P +S +  P++    S+ +QC  + +    + ++ K    R+  +R  +  +   +   F
Sbjct: 224 PSLSVQPGPMVAPGESLTLQC--VSDVGYDRFVLYKEGE-RDFLQRPGWQPQAGLSQANF 280

Query: 86  VIDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGENI 142
            +  +  +  G+Y+C   + +       SD L++++TG  Y +P LS      + PG+N+
Sbjct: 281 TLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNV 340

Query: 143 SLTCSSAHIPFDRFSLAKEGELSLP-----QHQSGEHPANFSLGPVDLNVSGIYRCYGWY 197
           +L C S    F  F L KEG    P     +HQ+ ++ A F +GPV     G YRCY   
Sbjct: 341 TLLCQSRG-QFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSL 399

Query: 198 NRSPYLWSFPSNALELVVTGRYRPVQP 224
           + +PYL S PS+ LELVV+     + P
Sbjct: 400 SSNPYLLSLPSDPLELVVSEAAETLSP 426



 Score = 34.3 bits (77), Expect = 0.098
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 10/106 (9%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPAN 177
           V  G   KP L A+ G V++ G  ++L C  + +  + + L +E + +    +  E   N
Sbjct: 21  VQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGS-LQAEEYHLYRENKSASWVRRIQEPGKN 79

Query: 178 --FSLGPVDLNVSGIYRC--YGWYNRSPYLWSFPSNALELVVTGRY 219
             F +  +    +G Y C  Y   + S Y     S+ LELVVTG Y
Sbjct: 80  GQFPIPSITWEHAGRYHCQYYSHNHSSEY-----SDPLELVVTGAY 120


>gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A
           (with TM domain), member 2 isoform b [Homo sapiens]
          Length = 466

 Score =  133 bits (334), Expect = 2e-31
 Identities = 88/223 (39%), Positives = 116/223 (52%), Gaps = 10/223 (4%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T L+CL L LG R   Q G  P P + A+   VI     V ++CQ   +A   + 
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQA--EEY 58

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
            + + +      RR++   +   +F I  +    AGRY CQY   ++   YSD LELVVT
Sbjct: 59  HLYRENKSASWVRRIQEPGKNG-QFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVT 117

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQ------HQSGEH 174
           G Y KP LSA    V+  G N++L C S  + FD F L KEGE   PQ      H  G  
Sbjct: 118 GAYSKPTLSALPSPVVTLGGNVTLQCVS-QVAFDGFILCKEGEDEHPQRLNSHSHARGWS 176

Query: 175 PANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
            A FS+GPV  +    YRCY + + SPY+WS PS+ LEL+V G
Sbjct: 177 WAIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPG 219



 Score = 96.3 bits (238), Expect = 2e-20
 Identities = 75/219 (34%), Positives = 114/219 (52%), Gaps = 24/219 (10%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGR-----RLKFW 78
           G +  P +SA  SPV+ L G+V +QC  + +      ++ K        R       + W
Sbjct: 118 GAYSKPTLSALPSPVVTLGGNVTLQC--VSQVAFDGFILCKEGEDEHPQRLNSHSHARGW 175

Query: 79  NETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYS---DTLELVVTGLYGKPFLSADRGLV 135
           +     F +  +  ++   Y+C     +  + +S   D LEL+V G+  KP LS   G +
Sbjct: 176 SWAI--FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPM 233

Query: 136 LMPGENISLTCSSAHIPFDRFSLAKEGE---LSLP--QHQSGEHPANFSLGPVDLNVSGI 190
           + PGE+++L C S  + +DRF L KEGE   L  P  Q Q+G   ANF+LGPV  +  G 
Sbjct: 234 VAPGESLTLQCVS-DVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQ 292

Query: 191 YRCYGWYNRSPYLWSFPSNALELVVTGRY--RP---VQP 224
           YRCY  +N S   WS PS+ L++++TG++  RP   VQP
Sbjct: 293 YRCYSAHNLSSE-WSAPSDPLDILITGQFYDRPSLSVQP 330



 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 58/199 (29%), Positives = 99/199 (49%), Gaps = 15/199 (7%)

Query: 29  PFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNE---TDPEF 85
           P +S +  P++    S+ +QC  + +    + ++ K    R+  +R  +  +   +   F
Sbjct: 224 PSLSVQPGPMVAPGESLTLQC--VSDVGYDRFVLYKEGE-RDFLQRPGWQPQAGLSQANF 280

Query: 86  VIDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGENI 142
            +  +  +  G+Y+C   + +       SD L++++TG  Y +P LS      + PG+N+
Sbjct: 281 TLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNV 340

Query: 143 SLTCSSAHIPFDRFSLAKEGELSLP-----QHQSGEHPANFSLGPVDLNVSGIYRCYGWY 197
           +L C S    F  F L KEG    P     +HQ+ ++ A F +GPV     G YRCY   
Sbjct: 341 TLLCQSRG-QFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSL 399

Query: 198 NRSPYLWSFPSNALELVVT 216
           + +PYL S PS+ LELVV+
Sbjct: 400 SSNPYLLSLPSDPLELVVS 418



 Score = 34.3 bits (77), Expect = 0.098
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 10/106 (9%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPAN 177
           V  G   KP L A+ G V++ G  ++L C  + +  + + L +E + +    +  E   N
Sbjct: 21  VQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGS-LQAEEYHLYRENKSASWVRRIQEPGKN 79

Query: 178 --FSLGPVDLNVSGIYRC--YGWYNRSPYLWSFPSNALELVVTGRY 219
             F +  +    +G Y C  Y   + S Y     S+ LELVVTG Y
Sbjct: 80  GQFPIPSITWEHAGRYHCQYYSHNHSSEY-----SDPLELVVTGAY 120


>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 4 [Homo sapiens]
          Length = 651

 Score =  128 bits (322), Expect = 4e-30
 Identities = 92/231 (39%), Positives = 113/231 (48%), Gaps = 24/231 (10%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T L+CL L LG R   Q G  P P + A+   VI     V ++CQ  +E    +L
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPE-------FVIDHMDANKAGRYQCQYRIGHY-RFRYS 112
                  YRE  ++   W    P+       F I  +    AGRY+C Y      R   S
Sbjct: 61  -------YRE--KKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESS 111

Query: 113 DTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQ---- 168
           D LELVVTG Y KP LSA    V+  G N+ L C S  + FD FSL KEGE   PQ    
Sbjct: 112 DPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDS-QVAFDGFSLCKEGEDEHPQCLNS 170

Query: 169 --HQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
             H  G   A FS+GPV  +    YRCY + + SPY WS PS+ LEL+V G
Sbjct: 171 QPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221



 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 63/207 (30%), Positives = 104/207 (50%), Gaps = 15/207 (7%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYRE---IGRRLKFWNE 80
           G +  P +SA+ SPV+   G+V +QC +  +       + K         +  +      
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDS--QVAFDGFSLCKEGEDEHPQCLNSQPHARGS 177

Query: 81  TDPEFVIDHMDANKAGRYQCQYRIGHYRFRYS---DTLELVVTGLYGKPFLSADRGLVLM 137
           +   F +  +  ++   Y+C     +  + +S   D LEL+V G+  KP LS   G ++ 
Sbjct: 178 SRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVA 237

Query: 138 PGENISLTCSSAHIPFDRFSLAKEGE-----LSLPQHQSGEHPANFSLGPVDLNVSGIYR 192
           P E ++L C S    ++RF L K+GE     L+  Q Q+G   ANF+LGPV  +  G YR
Sbjct: 238 PEETLTLQCGS-DAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296

Query: 193 CYGWYNRSPYLWSFPSNALELVVTGRY 219
           CYG +N S   WS PS+ L++++ G++
Sbjct: 297 CYGAHNLSSE-WSAPSDPLDILIAGQF 322



 Score = 78.2 bits (191), Expect = 6e-15
 Identities = 55/199 (27%), Positives = 97/199 (48%), Gaps = 13/199 (6%)

Query: 29  PFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNST--YREIGRRLKFWNETDPEFV 86
           P +S +  P++  + ++ +QC +  +A   + ++ K+    + ++         +   F 
Sbjct: 226 PSLSVQPGPIVAPEETLTLQCGS--DAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFT 283

Query: 87  IDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGENIS 143
           +  +  +  G+Y+C   + +       SD L++++ G  Y +  LS   G  +  GEN++
Sbjct: 284 LGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVT 343

Query: 144 LTCSSAHIPFDRFSLAKEGELSLP-----QHQSGEHPANFSLGPVDLNVSGIYRCYGWYN 198
           L C S       F L KEG    P      +QS ++ A F +GPV    +G YRCYG  +
Sbjct: 344 LLCQSQGW-MQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQS 402

Query: 199 RSPYLWSFPSNALELVVTG 217
             PYL + PS+ LELVV+G
Sbjct: 403 SKPYLLTHPSDPLELVVSG 421



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 10/107 (9%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSL-----PQHQSG 172
           V  G   KP L A+ G V+  G  ++L C         + L +E + +L     PQ    
Sbjct: 21  VQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYRLYREKKTALWITRIPQELVK 79

Query: 173 EHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
           +    F +  +    +G YRCY  Y       S  S+ LELVVTG Y
Sbjct: 80  K--GQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLELVVTGAY 122


>gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 3 [Homo sapiens]
          Length = 651

 Score =  128 bits (322), Expect = 4e-30
 Identities = 92/231 (39%), Positives = 113/231 (48%), Gaps = 24/231 (10%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T L+CL L LG R   Q G  P P + A+   VI     V ++CQ  +E    +L
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPE-------FVIDHMDANKAGRYQCQYRIGHY-RFRYS 112
                  YRE  ++   W    P+       F I  +    AGRY+C Y      R   S
Sbjct: 61  -------YRE--KKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESS 111

Query: 113 DTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQ---- 168
           D LELVVTG Y KP LSA    V+  G N+ L C S  + FD FSL KEGE   PQ    
Sbjct: 112 DPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDS-QVAFDGFSLCKEGEDEHPQCLNS 170

Query: 169 --HQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
             H  G   A FS+GPV  +    YRCY + + SPY WS PS+ LEL+V G
Sbjct: 171 QPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221



 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 63/207 (30%), Positives = 104/207 (50%), Gaps = 15/207 (7%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYRE---IGRRLKFWNE 80
           G +  P +SA+ SPV+   G+V +QC +  +       + K         +  +      
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDS--QVAFDGFSLCKEGEDEHPQCLNSQPHARGS 177

Query: 81  TDPEFVIDHMDANKAGRYQCQYRIGHYRFRYS---DTLELVVTGLYGKPFLSADRGLVLM 137
           +   F +  +  ++   Y+C     +  + +S   D LEL+V G+  KP LS   G ++ 
Sbjct: 178 SRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVA 237

Query: 138 PGENISLTCSSAHIPFDRFSLAKEGE-----LSLPQHQSGEHPANFSLGPVDLNVSGIYR 192
           P E ++L C S    ++RF L K+GE     L+  Q Q+G   ANF+LGPV  +  G YR
Sbjct: 238 PEETLTLQCGS-DAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296

Query: 193 CYGWYNRSPYLWSFPSNALELVVTGRY 219
           CYG +N S   WS PS+ L++++ G++
Sbjct: 297 CYGAHNLSSE-WSAPSDPLDILIAGQF 322



 Score = 78.2 bits (191), Expect = 6e-15
 Identities = 55/199 (27%), Positives = 97/199 (48%), Gaps = 13/199 (6%)

Query: 29  PFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNST--YREIGRRLKFWNETDPEFV 86
           P +S +  P++  + ++ +QC +  +A   + ++ K+    + ++         +   F 
Sbjct: 226 PSLSVQPGPIVAPEETLTLQCGS--DAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFT 283

Query: 87  IDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGENIS 143
           +  +  +  G+Y+C   + +       SD L++++ G  Y +  LS   G  +  GEN++
Sbjct: 284 LGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVT 343

Query: 144 LTCSSAHIPFDRFSLAKEGELSLP-----QHQSGEHPANFSLGPVDLNVSGIYRCYGWYN 198
           L C S       F L KEG    P      +QS ++ A F +GPV    +G YRCYG  +
Sbjct: 344 LLCQSQGW-MQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQS 402

Query: 199 RSPYLWSFPSNALELVVTG 217
             PYL + PS+ LELVV+G
Sbjct: 403 SKPYLLTHPSDPLELVVSG 421



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 10/107 (9%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSL-----PQHQSG 172
           V  G   KP L A+ G V+  G  ++L C         + L +E + +L     PQ    
Sbjct: 21  VQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYRLYREKKTALWITRIPQELVK 79

Query: 173 EHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
           +    F +  +    +G YRCY  Y       S  S+ LELVVTG Y
Sbjct: 80  K--GQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLELVVTGAY 122


>gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 2 [Homo sapiens]
          Length = 652

 Score =  128 bits (322), Expect = 4e-30
 Identities = 92/231 (39%), Positives = 113/231 (48%), Gaps = 24/231 (10%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T L+CL L LG R   Q G  P P + A+   VI     V ++CQ  +E    +L
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPE-------FVIDHMDANKAGRYQCQYRIGHY-RFRYS 112
                  YRE  ++   W    P+       F I  +    AGRY+C Y      R   S
Sbjct: 61  -------YRE--KKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESS 111

Query: 113 DTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQ---- 168
           D LELVVTG Y KP LSA    V+  G N+ L C S  + FD FSL KEGE   PQ    
Sbjct: 112 DPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDS-QVAFDGFSLCKEGEDEHPQCLNS 170

Query: 169 --HQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
             H  G   A FS+GPV  +    YRCY + + SPY WS PS+ LEL+V G
Sbjct: 171 QPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221



 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 63/207 (30%), Positives = 104/207 (50%), Gaps = 15/207 (7%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYRE---IGRRLKFWNE 80
           G +  P +SA+ SPV+   G+V +QC +  +       + K         +  +      
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDS--QVAFDGFSLCKEGEDEHPQCLNSQPHARGS 177

Query: 81  TDPEFVIDHMDANKAGRYQCQYRIGHYRFRYS---DTLELVVTGLYGKPFLSADRGLVLM 137
           +   F +  +  ++   Y+C     +  + +S   D LEL+V G+  KP LS   G ++ 
Sbjct: 178 SRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVA 237

Query: 138 PGENISLTCSSAHIPFDRFSLAKEGE-----LSLPQHQSGEHPANFSLGPVDLNVSGIYR 192
           P E ++L C S    ++RF L K+GE     L+  Q Q+G   ANF+LGPV  +  G YR
Sbjct: 238 PEETLTLQCGS-DAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296

Query: 193 CYGWYNRSPYLWSFPSNALELVVTGRY 219
           CYG +N S   WS PS+ L++++ G++
Sbjct: 297 CYGAHNLSSE-WSAPSDPLDILIAGQF 322



 Score = 78.2 bits (191), Expect = 6e-15
 Identities = 55/199 (27%), Positives = 97/199 (48%), Gaps = 13/199 (6%)

Query: 29  PFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNST--YREIGRRLKFWNETDPEFV 86
           P +S +  P++  + ++ +QC +  +A   + ++ K+    + ++         +   F 
Sbjct: 226 PSLSVQPGPIVAPEETLTLQCGS--DAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFT 283

Query: 87  IDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGENIS 143
           +  +  +  G+Y+C   + +       SD L++++ G  Y +  LS   G  +  GEN++
Sbjct: 284 LGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVT 343

Query: 144 LTCSSAHIPFDRFSLAKEGELSLP-----QHQSGEHPANFSLGPVDLNVSGIYRCYGWYN 198
           L C S       F L KEG    P      +QS ++ A F +GPV    +G YRCYG  +
Sbjct: 344 LLCQSQGW-MQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQS 402

Query: 199 RSPYLWSFPSNALELVVTG 217
             PYL + PS+ LELVV+G
Sbjct: 403 SKPYLLTHPSDPLELVVSG 421



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 10/107 (9%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSL-----PQHQSG 172
           V  G   KP L A+ G V+  G  ++L C         + L +E + +L     PQ    
Sbjct: 21  VQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYRLYREKKTALWITRIPQELVK 79

Query: 173 EHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
           +    F +  +    +G YRCY  Y       S  S+ LELVVTG Y
Sbjct: 80  K--GQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLELVVTGAY 122


>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 1 [Homo sapiens]
          Length = 650

 Score =  128 bits (322), Expect = 4e-30
 Identities = 92/231 (39%), Positives = 113/231 (48%), Gaps = 24/231 (10%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T L+CL L LG R   Q G  P P + A+   VI     V ++CQ  +E    +L
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPE-------FVIDHMDANKAGRYQCQYRIGHY-RFRYS 112
                  YRE  ++   W    P+       F I  +    AGRY+C Y      R   S
Sbjct: 61  -------YRE--KKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESS 111

Query: 113 DTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQ---- 168
           D LELVVTG Y KP LSA    V+  G N+ L C S  + FD FSL KEGE   PQ    
Sbjct: 112 DPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDS-QVAFDGFSLCKEGEDEHPQCLNS 170

Query: 169 --HQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
             H  G   A FS+GPV  +    YRCY + + SPY WS PS+ LEL+V G
Sbjct: 171 QPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221



 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 63/207 (30%), Positives = 104/207 (50%), Gaps = 15/207 (7%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYRE---IGRRLKFWNE 80
           G +  P +SA+ SPV+   G+V +QC +  +       + K         +  +      
Sbjct: 120 GAYIKPTLSAQPSPVVNSGGNVILQCDS--QVAFDGFSLCKEGEDEHPQCLNSQPHARGS 177

Query: 81  TDPEFVIDHMDANKAGRYQCQYRIGHYRFRYS---DTLELVVTGLYGKPFLSADRGLVLM 137
           +   F +  +  ++   Y+C     +  + +S   D LEL+V G+  KP LS   G ++ 
Sbjct: 178 SRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVA 237

Query: 138 PGENISLTCSSAHIPFDRFSLAKEGE-----LSLPQHQSGEHPANFSLGPVDLNVSGIYR 192
           P E ++L C S    ++RF L K+GE     L+  Q Q+G   ANF+LGPV  +  G YR
Sbjct: 238 PEETLTLQCGS-DAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYR 296

Query: 193 CYGWYNRSPYLWSFPSNALELVVTGRY 219
           CYG +N S   WS PS+ L++++ G++
Sbjct: 297 CYGAHNLSSE-WSAPSDPLDILIAGQF 322



 Score = 78.2 bits (191), Expect = 6e-15
 Identities = 55/199 (27%), Positives = 97/199 (48%), Gaps = 13/199 (6%)

Query: 29  PFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNST--YREIGRRLKFWNETDPEFV 86
           P +S +  P++  + ++ +QC +  +A   + ++ K+    + ++         +   F 
Sbjct: 226 PSLSVQPGPIVAPEETLTLQCGS--DAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFT 283

Query: 87  IDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGENIS 143
           +  +  +  G+Y+C   + +       SD L++++ G  Y +  LS   G  +  GEN++
Sbjct: 284 LGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVT 343

Query: 144 LTCSSAHIPFDRFSLAKEGELSLP-----QHQSGEHPANFSLGPVDLNVSGIYRCYGWYN 198
           L C S       F L KEG    P      +QS ++ A F +GPV    +G YRCYG  +
Sbjct: 344 LLCQSQGW-MQTFLLTKEGAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQS 402

Query: 199 RSPYLWSFPSNALELVVTG 217
             PYL + PS+ LELVV+G
Sbjct: 403 SKPYLLTHPSDPLELVVSG 421



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 10/107 (9%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSL-----PQHQSG 172
           V  G   KP L A+ G V+  G  ++L C         + L +E + +L     PQ    
Sbjct: 21  VQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQ-ETQEYRLYREKKTALWITRIPQELVK 79

Query: 173 EHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
           +    F +  +    +G YRCY  Y       S  S+ LELVVTG Y
Sbjct: 80  K--GQFPIPSITWEHAGRYRCY--YGSDTAGRSESSDPLELVVTGAY 122


>gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A,
           member 6 [Homo sapiens]
          Length = 481

 Score =  122 bits (306), Expect = 3e-28
 Identities = 85/223 (38%), Positives = 108/223 (48%), Gaps = 9/223 (4%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T LLCL L LG R + Q G FP P + A+   VI     V I CQ   EA   QL
Sbjct: 1   MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
              K  +   + R      +    F I  M  + AGRY+C Y         SD LELV+T
Sbjct: 61  --DKEGSPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMT 118

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLP------QHQSGEH 174
           G Y KP LSA    V+  G N++L C S    +  F L KEGE  LP      Q  SG  
Sbjct: 119 GFYNKPTLSALPSPVVASGGNMTLRCGSQK-GYHHFVLMKEGEHQLPRTLDSQQLHSGGF 177

Query: 175 PANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
            A F +GPV  +    + CY +Y  +P +WS PS+ LE++ +G
Sbjct: 178 QALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSG 220



 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 65/206 (31%), Positives = 107/206 (51%), Gaps = 15/206 (7%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTY---REIGRRLKFWNE 80
           G +  P +SA  SPV+   G++ ++C + +  +    +++K   +   R +  +      
Sbjct: 119 GFYNKPTLSALPSPVVASGGNMTLRCGSQKGYH--HFVLMKEGEHQLPRTLDSQQLHSGG 176

Query: 81  TDPEFVIDHMDANKAGRYQCQYRIGHYRFRYS---DTLELVVTGLYGKPFLSADRGLVLM 137
               F +  +  +   R+ C Y   +    +S   D LE++ +G+  KP L   +G VL 
Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236

Query: 138 PGENISLTCSSAHIPFDRFSLAKEGE---LSLP--QHQSGEHPANFSLGPVDLNVSGIYR 192
           PG++++L C S  + +DRF L KEGE   L  P  Q Q+G   ANF+LGPV  +  G YR
Sbjct: 237 PGQSLTLQCGS-DVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYR 295

Query: 193 CYGWYNRSPYLWSFPSNALELVVTGR 218
           CYG +N S   WS PS+ L +++ G+
Sbjct: 296 CYGAHNLSSE-WSAPSDPLNILMAGQ 320



 Score = 77.8 bits (190), Expect = 8e-15
 Identities = 49/141 (34%), Positives = 74/141 (52%), Gaps = 9/141 (6%)

Query: 85  FVIDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGEN 141
           F +  +  +  G+Y+C   + +       SD L +++ G +Y    LSA  G  +  GEN
Sbjct: 281 FTLGPVSPSHGGQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGEN 340

Query: 142 ISLTCSSAHIPFDRFSLAKEGELSLP-----QHQSGEHPANFSLGPVDLNVSGIYRCYGW 196
           ++L C S    FD F L KEG    P      + + ++ A F + PV    +G YRCYG 
Sbjct: 341 VTLLCQSRGY-FDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGS 399

Query: 197 YNRSPYLWSFPSNALELVVTG 217
           Y+ +P+L SFPS  LEL+V+G
Sbjct: 400 YSSNPHLLSFPSEPLELMVSG 420



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 7/105 (6%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPAN 177
           V  G + KP L A+ G V+  G  +++ C  + +    + L KEG        +   P N
Sbjct: 21  VQAGPFPKPTLWAEPGSVISWGSPVTIWCQGS-LEAQEYQLDKEGSPEPLDRNNPLEPKN 79

Query: 178 ---FSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
              FS+  +  + +G YRC+ + +     WS PS+ LELV+TG Y
Sbjct: 80  KARFSIPSMTQHHAGRYRCHYYSSAG---WSEPSDPLELVMTGFY 121


>gi|47519953 leukocyte immunoglobulin-like receptor subfamily A
           member 4 [Homo sapiens]
          Length = 499

 Score =  122 bits (306), Expect = 3e-28
 Identities = 83/218 (38%), Positives = 116/218 (53%), Gaps = 10/218 (4%)

Query: 6   TTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKN 65
           T+LL   L LG R + Q  + P P + A+  PVI     V I CQ   EA   +L    N
Sbjct: 6   TSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGN 65

Query: 66  STYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVTGLYGK 125
           S  R I + L+  +E   +  I  M    AGRY C Y+        SD LELVVT  Y +
Sbjct: 66  SMSRHILKTLE--SENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTA-YSR 122

Query: 126 PFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGE------LSLPQHQSGEHPANFS 179
           P LSA    V+  G N++L C+S  +   RF+L +EG+      L+  QH  G+  A F 
Sbjct: 123 PTLSALPSPVVTSGVNVTLRCAS-RLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFP 181

Query: 180 LGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
           +GP+  +  G +RCYG+ N +PY+WS PS+ L+L+V+G
Sbjct: 182 MGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSG 219



 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 68/224 (30%), Positives = 114/224 (50%), Gaps = 17/224 (7%)

Query: 26  FPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYR---EIGRRLKFWNETD 82
           +  P +SA  SPV+    +V ++C +     L +  +I+   +R    +        +  
Sbjct: 120 YSRPTLSALPSPVVTSGVNVTLRCAS--RLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQ 177

Query: 83  PEFVIDHMDANKAGRYQCQYRIGHYRFRYS---DTLELVVTGLYGKPFLSADRGLVLMPG 139
             F +  +  +  G ++C     +  + +S   D L+L+V+G+  KP L   +G V+ PG
Sbjct: 178 ALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPG 237

Query: 140 ENISLTCSSAHIPFDRFSLAKEGELSLPQH-----QSGEHPANFSLGPVDLNVSGIYRCY 194
           EN++L C S  + + R++L KEG   LPQ      Q+G   ANF+L PV  +  G YRCY
Sbjct: 238 ENLTLQCGS-DVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCY 296

Query: 195 GWYNRSPYLWSFPSNALELVVTGRYRPVQPCVWVGCPGPCHRAG 238
           G +N S   WS PS+ L++++ G+    +P + V  PGP   +G
Sbjct: 297 GAHNVSSE-WSAPSDPLDILIAGQISD-RPSLSVQ-PGPTVTSG 337



 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 47/148 (31%), Positives = 73/148 (49%), Gaps = 9/148 (6%)

Query: 85  FVIDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGEN 141
           F +  +  +  G+Y+C   + +       SD L++++ G +  +P LS   G  +  GE 
Sbjct: 280 FTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEK 339

Query: 142 ISLTCSSAHIPFDRFSLAKEGELSLP-----QHQSGEHPANFSLGPVDLNVSGIYRCYGW 196
           ++L C S   P   F L KEG    P      + + ++ A F + PV    +G YRCYG 
Sbjct: 340 VTLLCQSWD-PMFTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGS 398

Query: 197 YNRSPYLWSFPSNALELVVTGRYRPVQP 224
            + +PYL S PS  LELVV+G    + P
Sbjct: 399 RSSNPYLLSHPSEPLELVVSGATETLNP 426



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 36/119 (30%), Positives = 54/119 (45%), Gaps = 13/119 (10%)

Query: 125 KPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQH----QSGEHPANFSL 180
           KP L A+ G V+     +++ C    +    + L KEG  S+ +H       E+    S+
Sbjct: 28  KPILWAEPGPVITWHNPVTIWCQGT-LEAQGYRLDKEGN-SMSRHILKTLESENKVKLSI 85

Query: 181 GPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRYRPVQPCVWVGCPGPCHRAGI 239
             +    +G Y CY    +SP  WS PS+ LELVVT   RP    +    P P   +G+
Sbjct: 86  PSMMWEHAGRYHCY---YQSPAGWSEPSDPLELVVTAYSRPTLSAL----PSPVVTSGV 137


>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
           member 2 isoform 1 [Homo sapiens]
          Length = 598

 Score =  122 bits (305), Expect = 4e-28
 Identities = 86/223 (38%), Positives = 107/223 (47%), Gaps = 9/223 (4%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T L+CL L LG R   Q G  P P + A+   VI     V + CQ   EA   +L
Sbjct: 1   MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
              K S       R++     + +F I  +     GRY CQY         SD L LV+T
Sbjct: 61  YREKKSA--SWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMT 118

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQ------HQSGEH 174
           G Y KP LSA    V+  G  ++L C S  + F  F L KEGE   PQ      H  G  
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCES-QVAFGGFILCKEGEEEHPQCLNSQPHARGSS 177

Query: 175 PANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
            A FS+GPV  N    +RCYG+   SPY+WS PS+ LEL+V G
Sbjct: 178 RAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPG 220



 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 76/226 (33%), Positives = 116/226 (51%), Gaps = 17/226 (7%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYRE---IGRRLKFWNE 80
           G +P P +SA+ SPV+   G V +QC++  +      ++ K         +  +      
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCES--QVAFGGFILCKEGEEEHPQCLNSQPHARGS 176

Query: 81  TDPEFVIDHMDANKAGRYQCQ-YRIG--HYRFRYSDTLELVVTGLYGKPFLSADRGLVLM 137
           +   F +  +  N+   ++C  Y +   +     SD LEL+V G+  KP LS   G V+ 
Sbjct: 177 SRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVA 236

Query: 138 PGENISLTCSSAHIPFDRFSLAKEGELSL-----PQHQSGEHPANFSLGPVDLNVSGIYR 192
           PGE+++L C S  + +DRF L KEGE  L      Q Q+G   ANF+LGPV  +  G YR
Sbjct: 237 PGESLTLQCVS-DVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYR 295

Query: 193 CYGWYNRSPYLWSFPSNALELVVTGRYRPVQPCVWVGCPGPCHRAG 238
           CYG +N S    S PS+ L++++TG+ R   P + V  PGP   +G
Sbjct: 296 CYGAHNLSSEC-SAPSDPLDILITGQIRGT-PFISVQ-PGPTVASG 338



 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 60/199 (30%), Positives = 95/199 (47%), Gaps = 13/199 (6%)

Query: 29  PFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNST--YREIGRRLKFWNETDPEFV 86
           P +S +  PV+    S+ +QC  + +    + ++ K      R++  R      +   F 
Sbjct: 225 PSLSVQPGPVVAPGESLTLQC--VSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFT 282

Query: 87  IDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGENIS 143
           +  +  +  G+Y+C   + +       SD L++++TG + G PF+S   G  +  GEN++
Sbjct: 283 LGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVT 342

Query: 144 LTCSSAHIPFDRFSLAKEGELSLPQ-----HQSGEHPANFSLGPVDLNVSGIYRCYGWYN 198
           L C S    F  F L K G    P      H+  ++ A F + PV    +G YRCYG  N
Sbjct: 343 LLCQSWR-QFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLN 401

Query: 199 RSPYLWSFPSNALELVVTG 217
             PYL S PS  LELVV+G
Sbjct: 402 SDPYLLSHPSEPLELVVSG 420



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 33/118 (27%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTC----------------SSAHIPFDRFSLAKE 161
           V TG   KP L A+   V+  G  ++L+C                S++ I   R  L K 
Sbjct: 21  VQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKN 80

Query: 162 GELSLPQHQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
           G+  +P   + EH             +G Y C  +Y+R+   WS  S+ L LV+TG Y
Sbjct: 81  GQFHIPSI-TWEH-------------TGRYGCQ-YYSRAR--WSELSDPLVLVMTGAY 121


>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
           member 2 isoform 2 [Homo sapiens]
          Length = 597

 Score =  122 bits (305), Expect = 4e-28
 Identities = 86/223 (38%), Positives = 107/223 (47%), Gaps = 9/223 (4%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T L+CL L LG R   Q G  P P + A+   VI     V + CQ   EA   +L
Sbjct: 1   MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
              K S       R++     + +F I  +     GRY CQY         SD L LV+T
Sbjct: 61  YREKKSA--SWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMT 118

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQ------HQSGEH 174
           G Y KP LSA    V+  G  ++L C S  + F  F L KEGE   PQ      H  G  
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCES-QVAFGGFILCKEGEEEHPQCLNSQPHARGSS 177

Query: 175 PANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
            A FS+GPV  N    +RCYG+   SPY+WS PS+ LEL+V G
Sbjct: 178 RAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPG 220



 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 76/226 (33%), Positives = 116/226 (51%), Gaps = 17/226 (7%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYRE---IGRRLKFWNE 80
           G +P P +SA+ SPV+   G V +QC++  +      ++ K         +  +      
Sbjct: 119 GAYPKPTLSAQPSPVVTSGGRVTLQCES--QVAFGGFILCKEGEEEHPQCLNSQPHARGS 176

Query: 81  TDPEFVIDHMDANKAGRYQCQ-YRIG--HYRFRYSDTLELVVTGLYGKPFLSADRGLVLM 137
           +   F +  +  N+   ++C  Y +   +     SD LEL+V G+  KP LS   G V+ 
Sbjct: 177 SRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVA 236

Query: 138 PGENISLTCSSAHIPFDRFSLAKEGELSL-----PQHQSGEHPANFSLGPVDLNVSGIYR 192
           PGE+++L C S  + +DRF L KEGE  L      Q Q+G   ANF+LGPV  +  G YR
Sbjct: 237 PGESLTLQCVS-DVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYR 295

Query: 193 CYGWYNRSPYLWSFPSNALELVVTGRYRPVQPCVWVGCPGPCHRAG 238
           CYG +N S    S PS+ L++++TG+ R   P + V  PGP   +G
Sbjct: 296 CYGAHNLSSEC-SAPSDPLDILITGQIRGT-PFISVQ-PGPTVASG 338



 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 60/199 (30%), Positives = 95/199 (47%), Gaps = 13/199 (6%)

Query: 29  PFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNST--YREIGRRLKFWNETDPEFV 86
           P +S +  PV+    S+ +QC  + +    + ++ K      R++  R      +   F 
Sbjct: 225 PSLSVQPGPVVAPGESLTLQC--VSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFT 282

Query: 87  IDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGENIS 143
           +  +  +  G+Y+C   + +       SD L++++TG + G PF+S   G  +  GEN++
Sbjct: 283 LGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVT 342

Query: 144 LTCSSAHIPFDRFSLAKEGELSLPQ-----HQSGEHPANFSLGPVDLNVSGIYRCYGWYN 198
           L C S    F  F L K G    P      H+  ++ A F + PV    +G YRCYG  N
Sbjct: 343 LLCQSWR-QFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLN 401

Query: 199 RSPYLWSFPSNALELVVTG 217
             PYL S PS  LELVV+G
Sbjct: 402 SDPYLLSHPSEPLELVVSG 420



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 33/118 (27%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTC----------------SSAHIPFDRFSLAKE 161
           V TG   KP L A+   V+  G  ++L+C                S++ I   R  L K 
Sbjct: 21  VQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKN 80

Query: 162 GELSLPQHQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
           G+  +P   + EH             +G Y C  +Y+R+   WS  S+ L LV+TG Y
Sbjct: 81  GQFHIPSI-TWEH-------------TGRYGCQ-YYSRAR--WSELSDPLVLVMTGAY 121


>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
           member 3 isoform 1 [Homo sapiens]
          Length = 632

 Score =  120 bits (300), Expect = 1e-27
 Identities = 81/223 (36%), Positives = 109/223 (48%), Gaps = 9/223 (4%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T LLCL L LG R + Q G FP P + A+   VI     V I CQ  +EA   + 
Sbjct: 1   MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEA--QEY 58

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
            + K  +   + R      +    F I  M  + AGRY+C Y         SD LE+V+T
Sbjct: 59  RLHKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMT 118

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLP------QHQSGEH 174
           G Y KP LSA    V+  G N++L C S    +  F L KEGE  LP      Q  S   
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQK-GYHHFVLMKEGEHQLPRTLDSQQLHSRGF 177

Query: 175 PANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
            A F +GPV  +    + CY +Y  +P++WS PS+ LE++ +G
Sbjct: 178 QALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSG 220



 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 64/206 (31%), Positives = 108/206 (52%), Gaps = 15/206 (7%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTY---REIGRRLKFWNE 80
           G +  P +SA  SPV+   G++ ++C + +  +    +++K   +   R +  +      
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYH--HFVLMKEGEHQLPRTLDSQQLHSRG 176

Query: 81  TDPEFVIDHMDANKAGRYQCQYRIGHYRFRYS---DTLELVVTGLYGKPFLSADRGLVLM 137
               F +  +  +   R+ C Y   +  + +S   D LE++ +G+  KP L   +G VL 
Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236

Query: 138 PGENISLTCSSAHIPFDRFSLAKEGE---LSLP--QHQSGEHPANFSLGPVDLNVSGIYR 192
           PG++++L C S  + ++RF L KEGE   L  P  Q Q+G   ANF+LGPV  +  G YR
Sbjct: 237 PGQSLTLQCGS-DVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYR 295

Query: 193 CYGWYNRSPYLWSFPSNALELVVTGR 218
           CYG +N S   WS PS+ L +++ G+
Sbjct: 296 CYGAHNLSSE-WSAPSDPLNILMAGQ 320



 Score = 75.9 bits (185), Expect = 3e-14
 Identities = 49/141 (34%), Positives = 73/141 (51%), Gaps = 9/141 (6%)

Query: 85  FVIDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGEN 141
           F +  +  +  G+Y+C   + +       SD L +++ G +Y    LSA  G  +  GEN
Sbjct: 281 FTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGEN 340

Query: 142 ISLTCSSAHIPFDRFSLAKEGELSLP-----QHQSGEHPANFSLGPVDLNVSGIYRCYGW 196
           ++L C S    FD F L KEG    P      + + ++ A F + PV    +G YRCYG 
Sbjct: 341 VTLLCQSWW-QFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGS 399

Query: 197 YNRSPYLWSFPSNALELVVTG 217
           Y+ +P+L S PS  LELVV+G
Sbjct: 400 YSSNPHLLSHPSEPLELVVSG 420



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 7/105 (6%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPAN 177
           V  G + KP L A+ G V+  G  +++ C  +      + L KEG        +   P N
Sbjct: 21  VQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQ-EAQEYRLHKEGSPEPLDRNNPLEPKN 79

Query: 178 ---FSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
              FS+  +  + +G YRC+ + +     WS PS+ LE+V+TG Y
Sbjct: 80  KARFSIPSMTEHHAGRYRCHYYSSAG---WSEPSDPLEMVMTGAY 121


>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
           member 3 isoform 2 [Homo sapiens]
          Length = 631

 Score =  120 bits (300), Expect = 1e-27
 Identities = 81/223 (36%), Positives = 109/223 (48%), Gaps = 9/223 (4%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T LLCL L LG R + Q G FP P + A+   VI     V I CQ  +EA   + 
Sbjct: 1   MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEA--QEY 58

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
            + K  +   + R      +    F I  M  + AGRY+C Y         SD LE+V+T
Sbjct: 59  RLHKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMT 118

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLP------QHQSGEH 174
           G Y KP LSA    V+  G N++L C S    +  F L KEGE  LP      Q  S   
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQK-GYHHFVLMKEGEHQLPRTLDSQQLHSRGF 177

Query: 175 PANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
            A F +GPV  +    + CY +Y  +P++WS PS+ LE++ +G
Sbjct: 178 QALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSG 220



 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 64/206 (31%), Positives = 108/206 (52%), Gaps = 15/206 (7%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTY---REIGRRLKFWNE 80
           G +  P +SA  SPV+   G++ ++C + +  +    +++K   +   R +  +      
Sbjct: 119 GAYSKPTLSALPSPVVASGGNMTLRCGSQKGYH--HFVLMKEGEHQLPRTLDSQQLHSRG 176

Query: 81  TDPEFVIDHMDANKAGRYQCQYRIGHYRFRYS---DTLELVVTGLYGKPFLSADRGLVLM 137
               F +  +  +   R+ C Y   +  + +S   D LE++ +G+  KP L   +G VL 
Sbjct: 177 FQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236

Query: 138 PGENISLTCSSAHIPFDRFSLAKEGE---LSLP--QHQSGEHPANFSLGPVDLNVSGIYR 192
           PG++++L C S  + ++RF L KEGE   L  P  Q Q+G   ANF+LGPV  +  G YR
Sbjct: 237 PGQSLTLQCGS-DVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYR 295

Query: 193 CYGWYNRSPYLWSFPSNALELVVTGR 218
           CYG +N S   WS PS+ L +++ G+
Sbjct: 296 CYGAHNLSSE-WSAPSDPLNILMAGQ 320



 Score = 75.9 bits (185), Expect = 3e-14
 Identities = 49/141 (34%), Positives = 73/141 (51%), Gaps = 9/141 (6%)

Query: 85  FVIDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMPGEN 141
           F +  +  +  G+Y+C   + +       SD L +++ G +Y    LSA  G  +  GEN
Sbjct: 281 FTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGEN 340

Query: 142 ISLTCSSAHIPFDRFSLAKEGELSLP-----QHQSGEHPANFSLGPVDLNVSGIYRCYGW 196
           ++L C S    FD F L KEG    P      + + ++ A F + PV    +G YRCYG 
Sbjct: 341 VTLLCQSWW-QFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGS 399

Query: 197 YNRSPYLWSFPSNALELVVTG 217
           Y+ +P+L S PS  LELVV+G
Sbjct: 400 YSSNPHLLSHPSEPLELVVSG 420



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 7/105 (6%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPAN 177
           V  G + KP L A+ G V+  G  +++ C  +      + L KEG        +   P N
Sbjct: 21  VQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQ-EAQEYRLHKEGSPEPLDRNNPLEPKN 79

Query: 178 ---FSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
              FS+  +  + +G YRC+ + +     WS PS+ LE+V+TG Y
Sbjct: 80  KARFSIPSMTEHHAGRYRCHYYSSAG---WSEPSDPLEMVMTGAY 121


>gi|224586788 natural cytotoxicity triggering receptor 1 isoform c
           [Homo sapiens]
          Length = 287

 Score =  119 bits (298), Expect = 2e-27
 Identities = 79/210 (37%), Positives = 105/210 (50%), Gaps = 5/210 (2%)

Query: 8   LLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNST 67
           LLC+ LCL QRI AQ+   P PFI A+   ++P +  V I CQ    A   QL      +
Sbjct: 8   LLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQLHF--EGS 65

Query: 68  YREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVTGLYGKPF 127
              + R          +F I  M++  AG+Y C YR+G      S+ L+LVVT +Y  P 
Sbjct: 66  LFAVDRPKPPERINKVKFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEMYDTPT 125

Query: 128 LSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSLGPVDLNV 187
           LS   G  ++ GE ++  C         F L KEG  S  Q   G+  A F LGPV    
Sbjct: 126 LSVHPGPEVISGEKVTFYC-RLDTATSMFLLLKEGRSSHVQRGYGKVQAEFPLGPVTTAH 184

Query: 188 SGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
            G YRC+G YN   + WSFPS  ++L+VTG
Sbjct: 185 RGTYRCFGSYNN--HAWSFPSEPVKLLVTG 212



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 7/98 (7%)

Query: 125 KPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGEL---SLPQHQSGEHPANFSLG 181
           KPF+ A+   ++   + +++ C   +   + + L  EG L     P+     +   F + 
Sbjct: 28  KPFIWAEPHFMVPKEKQVTICCQGNYGAVE-YQLHFEGSLFAVDRPKPPERINKVKFYIP 86

Query: 182 PVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
            ++  ++G Y C     R   LWS PSN L+LVVT  Y
Sbjct: 87  DMNSRMAGQYSCI---YRVGELWSEPSNLLDLVVTEMY 121


>gi|224586786 natural cytotoxicity triggering receptor 1 isoform b
           [Homo sapiens]
          Length = 303

 Score =  119 bits (298), Expect = 2e-27
 Identities = 79/210 (37%), Positives = 105/210 (50%), Gaps = 5/210 (2%)

Query: 8   LLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNST 67
           LLC+ LCL QRI AQ+   P PFI A+   ++P +  V I CQ    A   QL      +
Sbjct: 8   LLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQLHF--EGS 65

Query: 68  YREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVTGLYGKPF 127
              + R          +F I  M++  AG+Y C YR+G      S+ L+LVVT +Y  P 
Sbjct: 66  LFAVDRPKPPERINKVKFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEMYDTPT 125

Query: 128 LSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSLGPVDLNV 187
           LS   G  ++ GE ++  C         F L KEG  S  Q   G+  A F LGPV    
Sbjct: 126 LSVHPGPEVISGEKVTFYC-RLDTATSMFLLLKEGRSSHVQRGYGKVQAEFPLGPVTTAH 184

Query: 188 SGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
            G YRC+G YN   + WSFPS  ++L+VTG
Sbjct: 185 RGTYRCFGSYNN--HAWSFPSEPVKLLVTG 212



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 7/98 (7%)

Query: 125 KPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGEL---SLPQHQSGEHPANFSLG 181
           KPF+ A+   ++   + +++ C   +   + + L  EG L     P+     +   F + 
Sbjct: 28  KPFIWAEPHFMVPKEKQVTICCQGNYGAVE-YQLHFEGSLFAVDRPKPPERINKVKFYIP 86

Query: 182 PVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
            ++  ++G Y C     R   LWS PSN L+LVVT  Y
Sbjct: 87  DMNSRMAGQYSCI---YRVGELWSEPSNLLDLVVTEMY 121


>gi|4758692 natural cytotoxicity triggering receptor 1 isoform a
           [Homo sapiens]
          Length = 304

 Score =  119 bits (298), Expect = 2e-27
 Identities = 79/210 (37%), Positives = 105/210 (50%), Gaps = 5/210 (2%)

Query: 8   LLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNST 67
           LLC+ LCL QRI AQ+   P PFI A+   ++P +  V I CQ    A   QL      +
Sbjct: 8   LLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQLHF--EGS 65

Query: 68  YREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVTGLYGKPF 127
              + R          +F I  M++  AG+Y C YR+G      S+ L+LVVT +Y  P 
Sbjct: 66  LFAVDRPKPPERINKVKFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEMYDTPT 125

Query: 128 LSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSLGPVDLNV 187
           LS   G  ++ GE ++  C         F L KEG  S  Q   G+  A F LGPV    
Sbjct: 126 LSVHPGPEVISGEKVTFYC-RLDTATSMFLLLKEGRSSHVQRGYGKVQAEFPLGPVTTAH 184

Query: 188 SGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
            G YRC+G YN   + WSFPS  ++L+VTG
Sbjct: 185 RGTYRCFGSYNN--HAWSFPSEPVKLLVTG 212



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 7/98 (7%)

Query: 125 KPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGEL---SLPQHQSGEHPANFSLG 181
           KPF+ A+   ++   + +++ C   +   + + L  EG L     P+     +   F + 
Sbjct: 28  KPFIWAEPHFMVPKEKQVTICCQGNYGAVE-YQLHFEGSLFAVDRPKPPERINKVKFYIP 86

Query: 182 PVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
            ++  ++G Y C     R   LWS PSN L+LVVT  Y
Sbjct: 87  DMNSRMAGQYSCI---YRVGELWSEPSNLLDLVVTEMY 121


>gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A
           (without TM domain), member 3 [Homo sapiens]
          Length = 439

 Score =  118 bits (296), Expect = 4e-27
 Identities = 87/228 (38%), Positives = 110/228 (48%), Gaps = 28/228 (12%)

Query: 6   TTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKN 65
           T L+CL L L  R   Q G  P P + A+   VI     V ++CQ   E     L     
Sbjct: 6   TVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHL----- 60

Query: 66  STYREIGRRLKFWNETDPE-------FVIDHMDANKAGRYQCQYRIGHYRF---RYSDTL 115
             YRE  ++   W    P+       F I  +    AGRY C Y  G +       SD L
Sbjct: 61  --YRE--KKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIY--GSHTVGLSESSDPL 114

Query: 116 ELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQ------H 169
           ELVVTG Y KP LSA    V+  G N+++ C S  + FD F L KEGE   PQ      H
Sbjct: 115 ELVVTGAYSKPTLSALPSPVVTSGGNVTIQCDS-QVAFDGFILCKEGEDEHPQCLNSHSH 173

Query: 170 QSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
             G   A FS+GPV  +    YRCYG+ +R+PY+WS PS+ L L+V G
Sbjct: 174 ARGSSRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPG 221



 Score = 85.1 bits (209), Expect = 5e-17
 Identities = 73/226 (32%), Positives = 107/226 (47%), Gaps = 17/226 (7%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYRE---IGRRLKFWNE 80
           G +  P +SA  SPV+   G+V IQC +  +      ++ K         +         
Sbjct: 120 GAYSKPTLSALPSPVVTSGGNVTIQCDS--QVAFDGFILCKEGEDEHPQCLNSHSHARGS 177

Query: 81  TDPEFVIDHMDANKAGRYQC---QYRIGHYRFRYSDTLELVVTGLYGKPFLSADRGLVLM 137
           +   F +  +  ++   Y+C     R  +     SD L L+V G+  KP LS   G V+ 
Sbjct: 178 SRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVA 237

Query: 138 PGENISLTCSSAHIPFDRFSLAKE---GELSLP--QHQSGEHPANFSLGPVDLNVSGIYR 192
           PGE ++  C S    +DRF L KE     L  P  Q Q+G   ANF+LGPV  +  G Y 
Sbjct: 238 PGEKLTFQCGS-DAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYT 296

Query: 193 CYGWYNRSPYLWSFPSNALELVVTGRYRPVQPCVWVGCPGPCHRAG 238
           C G YN S   WS PS+ L++++TG+ R  +P + V  PGP   +G
Sbjct: 297 CSGAYNLSSE-WSAPSDPLDILITGQIR-ARPFLSVR-PGPTVASG 339



 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 63/211 (29%), Positives = 99/211 (46%), Gaps = 23/211 (10%)

Query: 29  PFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNETDPE---- 84
           P +S +  PV+     +  QC +  +A   + ++     Y+E GR         P+    
Sbjct: 226 PSLSVQPGPVVAPGEKLTFQCGS--DAGYDRFVL-----YKEWGRDFLQRPGRQPQAGLS 278

Query: 85  ---FVIDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTG-LYGKPFLSADRGLVLMP 138
              F +  +  +  G+Y C   Y +       SD L++++TG +  +PFLS   G  +  
Sbjct: 279 QANFTLGPVSRSYGGQYTCSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVAS 338

Query: 139 GENISLTCSSAHIPFDRFSLAKEGELSLP-----QHQSGEHPANFSLGPVDLNVSGIYRC 193
           GEN++L C S       F L KEG    P     + QS ++ A F + PV    +G YRC
Sbjct: 339 GENVTLLCQSQG-GMHTFLLTKEGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRC 397

Query: 194 YGWYNRSPYLWSFPSNALELVVTGRYRPVQP 224
           YG  + +PYL + PS+ LELVV+G    + P
Sbjct: 398 YGSLSSNPYLLTHPSDPLELVVSGAAETLSP 428



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 10/107 (9%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSL-----PQHQSG 172
           V  G   KP L A+ G V+  G  ++L C  + +    + L +E + +L     PQ    
Sbjct: 21  VQAGPLPKPTLWAEPGSVITQGSPVTLRCQGS-LETQEYHLYREKKTALWITRIPQELVK 79

Query: 173 EHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
           +    F +  +    +G Y C   Y       S  S+ LELVVTG Y
Sbjct: 80  K--GQFPILSITWEHAGRYCCI--YGSHTVGLSESSDPLELVVTGAY 122


>gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B,
           member 4 isoform 2 [Homo sapiens]
          Length = 447

 Score =  118 bits (295), Expect = 5e-27
 Identities = 83/229 (36%), Positives = 110/229 (48%), Gaps = 8/229 (3%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T LLCL L LG R   Q G  P P + A+   VI    SV I CQ   EA   + 
Sbjct: 1   MIPTFTALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEA--REY 58

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
            + K  +     R+     +    F I  M  + AGRY+C YR      + SD LELV+T
Sbjct: 59  RLDKEESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMT 118

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELS-----LPQHQSGEHP 175
           G Y KP LSA    ++  G++++L C S   P D F L KE           +H + +H 
Sbjct: 119 GAYSKPTLSALPSPLVTSGKSVTLLCQSRS-PMDTFLLIKERAAHPLLHLRSEHGAQQHQ 177

Query: 176 ANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRYRPVQP 224
           A F + PV     G YRC+  +  S YL S PS+ LEL+V+G     +P
Sbjct: 178 AEFPMSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRP 226


>gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B,
           member 4 isoform 1 [Homo sapiens]
          Length = 448

 Score =  118 bits (295), Expect = 5e-27
 Identities = 83/229 (36%), Positives = 110/229 (48%), Gaps = 8/229 (3%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T LLCL L LG R   Q G  P P + A+   VI    SV I CQ   EA   + 
Sbjct: 1   MIPTFTALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEA--REY 58

Query: 61  MIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVT 120
            + K  +     R+     +    F I  M  + AGRY+C YR      + SD LELV+T
Sbjct: 59  RLDKEESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMT 118

Query: 121 GLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELS-----LPQHQSGEHP 175
           G Y KP LSA    ++  G++++L C S   P D F L KE           +H + +H 
Sbjct: 119 GAYSKPTLSALPSPLVTSGKSVTLLCQSRS-PMDTFLLIKERAAHPLLHLRSEHGAQQHQ 177

Query: 176 ANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRYRPVQP 224
           A F + PV     G YRC+  +  S YL S PS+ LEL+V+G     +P
Sbjct: 178 AEFPMSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRP 226


>gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A
           (with TM domain), member 1 [Homo sapiens]
          Length = 489

 Score =  114 bits (285), Expect = 7e-26
 Identities = 88/233 (37%), Positives = 112/233 (48%), Gaps = 28/233 (12%)

Query: 1   MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQL 60
           M P  T L+CL L LG R   Q G  P P + A+   VI     V + CQ I E    +L
Sbjct: 1   MTPIVTVLICLRLSLGPRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRL 60

Query: 61  MIIKNSTYREIGRRLKFWNETDPE-------FVIDHMDANKAGRYQCQYRIGHYRFRYS- 112
                  YRE  ++   W    P+       F I  +     GRY+C Y  G +   +S 
Sbjct: 61  -------YRE--KKTAPWITRIPQEIVKKGQFPIPSITWEHTGRYRCFY--GSHTAGWSE 109

Query: 113 --DTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQ-- 168
             D LELVVTG Y KP LSA    V+  G N++L C S  + F  F L KEGE   PQ  
Sbjct: 110 PSDPLELVVTGAYIKPTLSALPSPVVTSGGNVTLHCVS-QVAFGSFILCKEGEDEHPQCL 168

Query: 169 ----HQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTG 217
                  G   A FS+GPV  +    YRCY + + SP++WS PS+ LEL+V G
Sbjct: 169 NSQPRTHGWSRAIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLG 221



 Score = 99.4 bits (246), Expect = 2e-21
 Identities = 79/233 (33%), Positives = 116/233 (49%), Gaps = 31/233 (13%)

Query: 24  GDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIK----------NSTYREIGR 73
           G +  P +SA  SPV+   G+V + C  + +      ++ K          NS  R  G 
Sbjct: 120 GAYIKPTLSALPSPVVTSGGNVTLHC--VSQVAFGSFILCKEGEDEHPQCLNSQPRTHG- 176

Query: 74  RLKFWNETDPEFVIDHMDANKAGRYQC---QYRIGHYRFRYSDTLELVVTGLYGKPFLSA 130
               W+     F +  +  ++   Y+C        H     SD LEL+V G+  KP LS 
Sbjct: 177 ----WSRAI--FSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSV 230

Query: 131 DRGLVLMPGENISLTCSSAHIPFDRFSLAKEGE-----LSLPQHQSGEHPANFSLGPVDL 185
             G ++ PGE+++L C S  + +DRF L KEGE     L  PQ Q+G   ANF+LGPV  
Sbjct: 231 QPGPIVAPGESLTLQCVS-DVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSR 289

Query: 186 NVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRYRPVQPCVWVGCPGPCHRAG 238
           +  G YRC G YN S   WS PS+ L++++ G++R  +P + V  PGP   +G
Sbjct: 290 SYGGQYRCSGAYNLSSE-WSAPSDPLDILIAGQFRG-RPFISVH-PGPTVASG 339



 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 58/206 (28%), Positives = 100/206 (48%), Gaps = 13/206 (6%)

Query: 29  PFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNST--YREIGRRLKFWNETDPEFV 86
           P +S +  P++    S+ +QC  + +    + ++ K     + ++         +   F 
Sbjct: 226 PSLSVQPGPIVAPGESLTLQC--VSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFT 283

Query: 87  IDHMDANKAGRYQCQ--YRIGHYRFRYSDTLELVVTGLY-GKPFLSADRGLVLMPGENIS 143
           +  +  +  G+Y+C   Y +       SD L++++ G + G+PF+S   G  +  GEN++
Sbjct: 284 LGPVSRSYGGQYRCSGAYNLSSEWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVT 343

Query: 144 LTCSSAHIPFDRFSLAKEGELSLPQ-----HQSGEHPANFSLGPVDLNVSGIYRCYGWYN 198
           L C S   PF  F L K G    P      H+  ++ A F + PV    SG YRCYG  +
Sbjct: 344 LLCQSWG-PFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHSGTYRCYGSLS 402

Query: 199 RSPYLWSFPSNALELVVTGRYRPVQP 224
            +PYL S PS++LEL+V+G    + P
Sbjct: 403 SNPYLLSHPSDSLELMVSGAAETLSP 428



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 14/109 (12%)

Query: 118 VVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELS-----LPQH--Q 170
           V  G   KP L A+ G V+  G  ++L C    +    + L +E + +     +PQ   +
Sbjct: 21  VQAGTLPKPTLWAEPGSVITQGSPVTLWCQGI-LETQEYRLYREKKTAPWITRIPQEIVK 79

Query: 171 SGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTGRY 219
            G+ P    +  +    +G YRC+  Y      WS PS+ LELVVTG Y
Sbjct: 80  KGQFP----IPSITWEHTGRYRCF--YGSHTAGWSEPSDPLELVVTGAY 122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.140    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,922,815
Number of Sequences: 37866
Number of extensions: 433919
Number of successful extensions: 1510
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 1016
Number of HSP's gapped (non-prelim): 238
length of query: 239
length of database: 18,247,518
effective HSP length: 99
effective length of query: 140
effective length of database: 14,498,784
effective search space: 2029829760
effective search space used: 2029829760
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press