Guide to the Human Genome
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Search of human proteins with 196123579

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|196123579 NADH dehydrogenase subunit 1 [Homo sapiens
neanderthalensis]
         (318 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|196123579 NADH dehydrogenase subunit 1 [Homo sapiens neandert...   629   e-180
gi|251831107 NADH dehydrogenase subunit 1 [Homo sapiens]              623   e-179
gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]                    30   2.2  
gi|149193323 threonine synthase-like 2 [Homo sapiens]                  29   4.8  
gi|167466160 chloride channel 7 isoform b [Homo sapiens]               29   6.3  
gi|14149607 chloride channel 7 isoform a [Homo sapiens]                29   6.3  
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur...    29   6.3  
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur...    29   6.3  
gi|30795238 ATP-binding cassette, sub-family A, member 12 isofor...    28   8.2  

>gi|196123579 NADH dehydrogenase subunit 1 [Homo sapiens
           neanderthalensis]
          Length = 318

 Score =  629 bits (1622), Expect = e-180
 Identities = 318/318 (100%), Positives = 318/318 (100%)

Query: 1   TPMANLLLLVVPILIAMAFLMLTERKILGYMQLRKGPNVVGPYGLLQPFADAMKLFTKEP 60
           TPMANLLLLVVPILIAMAFLMLTERKILGYMQLRKGPNVVGPYGLLQPFADAMKLFTKEP
Sbjct: 1   TPMANLLLLVVPILIAMAFLMLTERKILGYMQLRKGPNVVGPYGLLQPFADAMKLFTKEP 60

Query: 61  LKPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSG 120
           LKPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSG
Sbjct: 61  LKPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSG 120

Query: 121 WASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSFNLSTLITAQEHLWLLLPSWP 180
           WASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSFNLSTLITAQEHLWLLLPSWP
Sbjct: 121 WASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSFNLSTLITAQEHLWLLLPSWP 180

Query: 181 LAMMWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTT 240
           LAMMWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTT
Sbjct: 181 LAMMWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTT 240

Query: 241 IFLGTTYNALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHLLWKNFLPLTLAL 300
           IFLGTTYNALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHLLWKNFLPLTLAL
Sbjct: 241 IFLGTTYNALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHLLWKNFLPLTLAL 300

Query: 301 LMWYVSMPITISSIPPQT 318
           LMWYVSMPITISSIPPQT
Sbjct: 301 LMWYVSMPITISSIPPQT 318


>gi|251831107 NADH dehydrogenase subunit 1 [Homo sapiens]
          Length = 318

 Score =  623 bits (1607), Expect = e-179
 Identities = 314/317 (99%), Positives = 316/317 (99%)

Query: 2   PMANLLLLVVPILIAMAFLMLTERKILGYMQLRKGPNVVGPYGLLQPFADAMKLFTKEPL 61
           PMANLLLL+VPILIAMAFLMLTERKILGYMQLRKGPNVVGPYGLLQPFADAMKLFTKEPL
Sbjct: 2   PMANLLLLIVPILIAMAFLMLTERKILGYMQLRKGPNVVGPYGLLQPFADAMKLFTKEPL 61

Query: 62  KPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSGW 121
           KPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSGW
Sbjct: 62  KPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSGW 121

Query: 122 ASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSFNLSTLITAQEHLWLLLPSWPL 181
           ASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSFNLSTLIT QEHLWLLLPSWPL
Sbjct: 122 ASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSFNLSTLITTQEHLWLLLPSWPL 181

Query: 182 AMMWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTTI 241
           AMMWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTTI
Sbjct: 182 AMMWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTTI 241

Query: 242 FLGTTYNALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHLLWKNFLPLTLALL 301
           FLGTTY+ALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHLLWKNFLPLTLALL
Sbjct: 242 FLGTTYDALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHLLWKNFLPLTLALL 301

Query: 302 MWYVSMPITISSIPPQT 318
           MWYVSMPITISSIPPQT
Sbjct: 302 MWYVSMPITISSIPPQT 318


>gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]
          Length = 710

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 8/81 (9%)

Query: 98  LNLGLLFILATSSLAVYSILWSGWASNSNYALIGALRAVAQTI------SYEVTLAIILL 151
           L L  L ILA  SL   +   SGW  N++  L  +L     T+       ++  L+ +L 
Sbjct: 545 LCLSCLHILAEQSLKKENHACSGWLHNTSSWLASSLAIYRPTVLKFLANGWQKYLSTLLY 604

Query: 152 STLLMSGSFNLSTLITAQEHL 172
           +T   S  F  ST I  Q HL
Sbjct: 605 NTANYSSEFEASTYI--QHHL 623


>gi|149193323 threonine synthase-like 2 [Homo sapiens]
          Length = 484

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 13/105 (12%)

Query: 184 MWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTTIFL 243
           MW++ST     R  F     E  L SG+       P    FM E    +   TL     L
Sbjct: 1   MWYVSTRGVAPRVNF-----EGALFSGY------APDGGLFMPEELPQLDRGTLCQWSTL 49

Query: 244 GTTYNALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHL 288
             +Y  L  EL   +  ++ L    L   I  A+ RFR+ +++HL
Sbjct: 50  --SYPGLVKELCALFIGSELLPKDELNDLIDRAFSRFRHREVVHL 92


>gi|167466160 chloride channel 7 isoform b [Homo sapiens]
          Length = 781

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 8/84 (9%)

Query: 68  ITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSGWASNSNY 127
           +  ++   T  LT++  ++    +P+ L+    G LF ++ S L   +I    WA    Y
Sbjct: 472 VYFFLACWTYGLTVSAGVF----IPSLLIGAAWGRLFGISLSYLTGAAI----WADPGKY 523

Query: 128 ALIGALRAVAQTISYEVTLAIILL 151
           AL+GA   +   +   ++L +I++
Sbjct: 524 ALMGAAAQLGGIVRMTLSLTVIMM 547


>gi|14149607 chloride channel 7 isoform a [Homo sapiens]
          Length = 805

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 8/84 (9%)

Query: 68  ITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSILWSGWASNSNY 127
           +  ++   T  LT++  ++    +P+ L+    G LF ++ S L   +I    WA    Y
Sbjct: 496 VYFFLACWTYGLTVSAGVF----IPSLLIGAAWGRLFGISLSYLTGAAI----WADPGKY 547

Query: 128 ALIGALRAVAQTISYEVTLAIILL 151
           AL+GA   +   +   ++L +I++
Sbjct: 548 ALMGAAAQLGGIVRMTLSLTVIMM 571


>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
           [Homo sapiens]
          Length = 936

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 8/113 (7%)

Query: 58  KEPLKPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSIL 117
           + P    TS +TLY+     A++   L +  + + + L   +   L   +   L      
Sbjct: 683 ESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSRLLQASGGGLT----- 737

Query: 118 WSGWASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSFNLSTLITAQE 170
                S S++  +  +RA  QT S+EV+L      + L+    N +  + +QE
Sbjct: 738 ---GVSGSHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLISQE 787


>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
           [Homo sapiens]
          Length = 850

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 8/113 (7%)

Query: 58  KEPLKPATSTITLYITAPTLALTIALLLWTPLPMPNPLVNLNLGLLFILATSSLAVYSIL 117
           + P    TS +TLY+     A++   L +  + + + L   +   L   +   L      
Sbjct: 683 ESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSRLLQASGGGLT----- 737

Query: 118 WSGWASNSNYALIGALRAVAQTISYEVTLAIILLSTLLMSGSFNLSTLITAQE 170
                S S++  +  +RA  QT S+EV+L      + L+    N +  + +QE
Sbjct: 738 ---GVSGSHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLISQE 787


>gi|30795238 ATP-binding cassette, sub-family A, member 12 isoform a
           [Homo sapiens]
          Length = 2595

 Score = 28.5 bits (62), Expect = 8.2
 Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 10/45 (22%)

Query: 282 YDQLMHLLWKNFL-----PL-TLALLMW----YVSMPITISSIPP 316
           + QL  L+WKN+L     PL TL L++W    ++ + IT +  PP
Sbjct: 5   FHQLQILVWKNWLGVKRQPLWTLVLILWPVIIFIILAITRTKFPP 49


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.137    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,837,763
Number of Sequences: 37866
Number of extensions: 434271
Number of successful extensions: 1297
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1294
Number of HSP's gapped (non-prelim): 10
length of query: 318
length of database: 18,247,518
effective HSP length: 102
effective length of query: 216
effective length of database: 14,385,186
effective search space: 3107200176
effective search space used: 3107200176
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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