BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|194294562 purinergic receptor P2Y, G-protein coupled, 13 [Homo sapiens] (354 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|194294562 purinergic receptor P2Y, G-protein coupled, 13 [Hom... 708 0.0 gi|29029605 purinergic receptor P2Y12 [Homo sapiens] 320 9e-88 gi|12232483 purinergic receptor P2Y12 [Homo sapiens] 320 9e-88 gi|125625354 P2Y14 receptor [Homo sapiens] 303 2e-82 gi|125625352 P2Y14 receptor [Homo sapiens] 303 2e-82 gi|224586796 G protein-coupled receptor 87 [Homo sapiens] 267 1e-71 gi|153792776 G protein-coupled receptor 171 [Homo sapiens] 193 2e-49 gi|148225857 G protein-coupled receptor 34 [Homo sapiens] 149 5e-36 gi|4885319 G protein-coupled receptor 34 [Homo sapiens] 149 5e-36 gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens] 139 5e-33 gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 137 2e-32 gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 137 2e-32 gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 137 2e-32 gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 137 2e-32 gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens] 128 9e-30 gi|4506241 platelet-activating factor receptor [Homo sapiens] 126 3e-29 gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] 112 7e-25 gi|14043066 angiotensin II receptor, type 1 [Homo sapiens] 111 1e-24 gi|14043064 angiotensin II receptor, type 1 [Homo sapiens] 111 1e-24 gi|14043062 angiotensin II receptor, type 1 [Homo sapiens] 111 1e-24 gi|6715583 angiotensin II receptor, type 1 [Homo sapiens] 111 1e-24 gi|4501997 angiotensin II receptor, type 1 [Homo sapiens] 111 1e-24 gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 110 2e-24 gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 110 2e-24 gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 110 2e-24 gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] 108 9e-24 gi|28872720 purinergic receptor P2Y2 [Homo sapiens] 106 3e-23 gi|28872745 purinergic receptor P2Y2 [Homo sapiens] 106 3e-23 gi|28872743 purinergic receptor P2Y2 [Homo sapiens] 106 3e-23 gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens] 106 3e-23 >gi|194294562 purinergic receptor P2Y, G-protein coupled, 13 [Homo sapiens] Length = 354 Score = 708 bits (1828), Expect = 0.0 Identities = 354/354 (100%), Positives = 354/354 (100%) Query: 1 MTAAIRRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGIL 60 MTAAIRRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGIL Sbjct: 1 MTAAIRRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGIL 60 Query: 61 LNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSS 120 LNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSS Sbjct: 61 LNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSS 120 Query: 121 VIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTI 180 VIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTI Sbjct: 121 VIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTI 180 Query: 181 LSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYR 240 LSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYR Sbjct: 181 LSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYR 240 Query: 241 KSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKE 300 KSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKE Sbjct: 241 KSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKE 300 Query: 301 TTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTASSQENHSSQTDNITLG 354 TTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTASSQENHSSQTDNITLG Sbjct: 301 TTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTASSQENHSSQTDNITLG 354 >gi|29029605 purinergic receptor P2Y12 [Homo sapiens] Length = 342 Score = 320 bits (821), Expect = 9e-88 Identities = 154/316 (48%), Positives = 211/316 (66%), Gaps = 2/316 (0%) Query: 36 CPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLM 95 C RD +I Q++FP LYTV+F G++ N LA+ +F I S S FII+LKNT+++DL+M L Sbjct: 17 CTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILT 76 Query: 96 LPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLK 155 PFKILSD+ L LR FVC+ +SVIFY TMY+ I LGLI DR+ K RP + K Sbjct: 77 FPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPK 136 Query: 156 KPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQF 215 + AK +S+ IW F+F +SLPN IL+N++ +VKKC+ LK GL WH++VN ICQ Sbjct: 137 NLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQV 196 Query: 216 IFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFAR 275 IFW F++++V Y +I K++Y SY +++ + KK+ KVF+++AVFF+CF PFHFAR Sbjct: 197 IFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFAR 256 Query: 276 VPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQ--G 333 +PYT SQT + DC +N LF KE+TL+L + N C+DP IY FLCK F L M Sbjct: 257 IPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCP 316 Query: 334 RKTTASSQENHSSQTD 349 T+ SQ+N + D Sbjct: 317 NSATSLSQDNRKKEQD 332 >gi|12232483 purinergic receptor P2Y12 [Homo sapiens] Length = 342 Score = 320 bits (821), Expect = 9e-88 Identities = 154/316 (48%), Positives = 211/316 (66%), Gaps = 2/316 (0%) Query: 36 CPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLM 95 C RD +I Q++FP LYTV+F G++ N LA+ +F I S S FII+LKNT+++DL+M L Sbjct: 17 CTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILT 76 Query: 96 LPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLK 155 PFKILSD+ L LR FVC+ +SVIFY TMY+ I LGLI DR+ K RP + K Sbjct: 77 FPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPK 136 Query: 156 KPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQF 215 + AK +S+ IW F+F +SLPN IL+N++ +VKKC+ LK GL WH++VN ICQ Sbjct: 137 NLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQV 196 Query: 216 IFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFAR 275 IFW F++++V Y +I K++Y SY +++ + KK+ KVF+++AVFF+CF PFHFAR Sbjct: 197 IFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFAR 256 Query: 276 VPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQ--G 333 +PYT SQT + DC +N LF KE+TL+L + N C+DP IY FLCK F L M Sbjct: 257 IPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCP 316 Query: 334 RKTTASSQENHSSQTD 349 T+ SQ+N + D Sbjct: 317 NSATSLSQDNRKKEQD 332 >gi|125625354 P2Y14 receptor [Homo sapiens] Length = 338 Score = 303 bits (775), Expect = 2e-82 Identities = 140/295 (47%), Positives = 193/295 (65%) Query: 34 ERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTLVADLIMT 93 E C ++ I Q + P LY +VF+ GILLN ++ W+F ++PSS +FIIYLKN ++AD +M+ Sbjct: 12 ESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMS 71 Query: 94 LMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIF 153 L PFKIL DS L PWQL FVCR S+V+FY MYV IV GLI+FDR+ KI++PL F Sbjct: 72 LTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSF 131 Query: 154 LKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNIC 213 ++ ++K +S+ +W + +++PN IL+N+ + KC LK LG KWH+ N I Sbjct: 132 IQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIF 191 Query: 214 QFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHF 273 IFW VF+L++VFY I KK++ S+ KS KK +F +V VFFVCF P+H Sbjct: 192 VAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHI 251 Query: 274 ARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKL 328 AR+PYT SQT C+ + L KE TL L+A N+C+DP+IY FLC+ F E L Sbjct: 252 ARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREIL 306 >gi|125625352 P2Y14 receptor [Homo sapiens] Length = 338 Score = 303 bits (775), Expect = 2e-82 Identities = 140/295 (47%), Positives = 193/295 (65%) Query: 34 ERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTLVADLIMT 93 E C ++ I Q + P LY +VF+ GILLN ++ W+F ++PSS +FIIYLKN ++AD +M+ Sbjct: 12 ESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMS 71 Query: 94 LMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIF 153 L PFKIL DS L PWQL FVCR S+V+FY MYV IV GLI+FDR+ KI++PL F Sbjct: 72 LTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSF 131 Query: 154 LKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNIC 213 ++ ++K +S+ +W + +++PN IL+N+ + KC LK LG KWH+ N I Sbjct: 132 IQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIF 191 Query: 214 QFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHF 273 IFW VF+L++VFY I KK++ S+ KS KK +F +V VFFVCF P+H Sbjct: 192 VAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHI 251 Query: 274 ARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKL 328 AR+PYT SQT C+ + L KE TL L+A N+C+DP+IY FLC+ F E L Sbjct: 252 ARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREIL 306 >gi|224586796 G protein-coupled receptor 87 [Homo sapiens] Length = 358 Score = 267 bits (682), Expect = 1e-71 Identities = 125/305 (40%), Positives = 194/305 (63%), Gaps = 11/305 (3%) Query: 31 NRSERCPRDTRIVQ----LVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTL 86 NRS+ ++T + +V P LY ++F+ ILLN LA+W+F HI + ++FI YLKN + Sbjct: 25 NRSDGPGKNTTLHNEFDTIVLPVLYLIIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIV 84 Query: 87 VADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKII 146 VADLIMTL PF+I+ D+ PW + +CR++SV+FY MY IV LGLI+ DR+LK++ Sbjct: 85 VADLIMTLTFPFRIVHDAGFGPWYFKFILCRYTSVLFYANMYTSIVFLGLISIDRYLKVV 144 Query: 147 RPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWH 206 +P + + F K +S+ +W + +SLPN IL+N + T ++ C+ LK PLG+KWH Sbjct: 145 KPFGDSRMYSITFTKVLSVCVWVIMAVLSLPNIILTNGQPTEDNIHDCSKLKSPLGVKWH 204 Query: 207 QMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRK---SKSKDRKNNKKLEGKVFVVVAV 263 V + +F V ++++ Y+ I++ ++ S R+ S+ RK+N+ + VVVAV Sbjct: 205 TAVTYVNSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIR----VVVAV 260 Query: 264 FFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKK 323 FF CF P+H R+P+T S + D Q L+ KE TLFL+A N+C+DP+IY F+C+ Sbjct: 261 FFTCFLPYHLCRIPFTFSHLDRLLDESAQKILYYCKEITLFLSACNVCLDPIIYFFMCRS 320 Query: 324 FTEKL 328 F+ +L Sbjct: 321 FSRRL 325 >gi|153792776 G protein-coupled receptor 171 [Homo sapiens] Length = 319 Score = 193 bits (491), Expect = 2e-49 Identities = 101/302 (33%), Positives = 164/302 (54%), Gaps = 9/302 (2%) Query: 47 FPALYTVVFLTGILLNTLALWVFVHIPSSSTFI-IYLKNTLVADLIMTLMLPFKILSDSH 105 F + +VFL GI+ + A W F+ ++ + IYL N L AD ++TL LP KI+ D Sbjct: 17 FTYFFYLVFLVGIIGSCFATWAFIQKNTNHRCVSIYLINLLTADFLLTLALPVKIVVDLG 76 Query: 106 LAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSI 165 +APW+L+ F C+ ++ + Y MY+ I+ L ++ DR L++ + +++P FAK +S Sbjct: 77 VAPWKLKIFHCQVTACLIYINMYLSIIFLAFVSIDRCLQLTHSCKIYRIQEPGFAKMIST 136 Query: 166 FIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILML 225 +W + I +PN ++ K+ S C K G WH + N IC IF ++L Sbjct: 137 VVWLMVLLIMVPNMMIPIKDIKEKSNVGCMEFKKEFGRNWHLLTNFICVAIFLNFSAIIL 196 Query: 226 VFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNN 285 + ++ +++ YR +++ N KK + +V + +CF P+H R+PYT SQT Sbjct: 197 ISNCLVIRQL---YRNKDNENYPNVKKALINILLVTTGYIICFVPYHIVRIPYTLSQTEV 253 Query: 286 KTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTASSQENHS 345 TDC + LF AKE TL LA +N+C DP++Y L K F K+ +T AS +E + Sbjct: 254 ITDCSTRISLFKAKEATLLLAVSNLCFDPILYYHLSKAFRSKV-----TETFASPKETKA 308 Query: 346 SQ 347 + Sbjct: 309 QK 310 >gi|148225857 G protein-coupled receptor 34 [Homo sapiens] Length = 381 Score = 149 bits (375), Expect = 5e-36 Identities = 92/300 (30%), Positives = 152/300 (50%), Gaps = 11/300 (3%) Query: 36 CPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFI-IYLKNTLVADLIMTL 94 CP D +++ V Y+V+F+ G++ N +AL+VF+ I I IYL N +ADL++ Sbjct: 46 CPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIF 105 Query: 95 MLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRN--- 151 LPF+I+ + W L +C+ +FY MY+ I+LLG I+ DR++KI R ++ Sbjct: 106 CLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKA 165 Query: 152 IFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNN 211 I K+ ++ V +W L IL+ K+ +S C + K + N Sbjct: 166 ITTKQSIY---VCCIVWMLALGGFLTMIILTLKKGGHNST-MCFHYRDKHNAKGEAIFNF 221 Query: 212 ICQFIFWTVFILMLVFYVVIAKKVYD-SYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAP 270 I +FW +F+L+++ Y+ I K + S R+SK + F+V+ +F +CF P Sbjct: 222 ILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVP 281 Query: 271 FHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPC 330 +H R Y SQ N + C + + E L L++ N C+DP++Y FL K+ C Sbjct: 282 YHAFRFIYISSQL-NVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMY-FLMSSNIRKIMC 339 >gi|4885319 G protein-coupled receptor 34 [Homo sapiens] Length = 381 Score = 149 bits (375), Expect = 5e-36 Identities = 92/300 (30%), Positives = 152/300 (50%), Gaps = 11/300 (3%) Query: 36 CPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFI-IYLKNTLVADLIMTL 94 CP D +++ V Y+V+F+ G++ N +AL+VF+ I I IYL N +ADL++ Sbjct: 46 CPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRNSIQIYLLNVAIADLLLIF 105 Query: 95 MLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRN--- 151 LPF+I+ + W L +C+ +FY MY+ I+LLG I+ DR++KI R ++ Sbjct: 106 CLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKA 165 Query: 152 IFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNN 211 I K+ ++ V +W L IL+ K+ +S C + K + N Sbjct: 166 ITTKQSIY---VCCIVWMLALGGFLTMIILTLKKGGHNST-MCFHYRDKHNAKGEAIFNF 221 Query: 212 ICQFIFWTVFILMLVFYVVIAKKVYD-SYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAP 270 I +FW +F+L+++ Y+ I K + S R+SK + F+V+ +F +CF P Sbjct: 222 ILVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVP 281 Query: 271 FHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPC 330 +H R Y SQ N + C + + E L L++ N C+DP++Y FL K+ C Sbjct: 282 YHAFRFIYISSQL-NVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMY-FLMSSNIRKIMC 339 >gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens] Length = 361 Score = 139 bits (349), Expect = 5e-33 Identities = 83/302 (27%), Positives = 158/302 (52%), Gaps = 8/302 (2%) Query: 44 QLVFPALYTVVFLTGILLNTLALWVFVHIPSS-STFIIYLKNTLVADLIMTLMLPFKILS 102 ++V P Y++VF+ G++ N LAL V V ++ +Y N +++D++ T LP +I Sbjct: 31 RIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAY 90 Query: 103 DSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKT 162 + W++ +CR ++++FY Y G+ + ++ DRF+ ++ PLR +K+ AK Sbjct: 91 YAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKG 150 Query: 163 VSIFIWFFLFFISLPNTI--LSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTV 220 V IF+W +F +LP I +S +EA + + + + L W ++ C + Sbjct: 151 VCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPW--ILLGACFIGYVLP 208 Query: 221 FILMLVFYVVIAKKVYDSYRKSKSKDRKN-NKKLEGKVFVVVAVFFVCFAPFHFARVPYT 279 I++L+ Y I K++ + +++ ++ NKK + +++ VF +CF P+H A + + Sbjct: 209 LIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHM 268 Query: 280 HSQT--NNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTT 337 + +N +C ++ I+ T+ L N CMDP IY F CK + K+ M R+ + Sbjct: 269 IKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRMLKRQVS 328 Query: 338 AS 339 S Sbjct: 329 VS 330 >gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] Length = 339 Score = 137 bits (344), Expect = 2e-32 Identities = 82/297 (27%), Positives = 148/297 (49%), Gaps = 9/297 (3%) Query: 33 SERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFI-IYLKNTLVADLI 91 +E+C ++T + ++F + Y + F+ ++ NTLALW+F+ S T ++L + VADL Sbjct: 20 AEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLS 79 Query: 92 MTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRN 151 L+LP +++ W CR + +FY MY I L I+ DRFL I+ P+++ Sbjct: 80 CVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKS 139 Query: 152 IFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNN 211 + L++P++A F+W + +++ ++S + + C L H +V+ Sbjct: 140 LKLRRPLYAHLACAFLW-VVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKA-SHHALVSL 197 Query: 212 ICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPF 271 F F FI + Y++I + S R+ +++ K + +V+A+F VCF P+ Sbjct: 198 AVAFTF--PFITTVTCYLLIIR----SLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPY 251 Query: 272 HFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKL 328 H R Y ++ C Q L +A T L + N +DP++Y F+ +KF L Sbjct: 252 HVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHAL 308 >gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] Length = 339 Score = 137 bits (344), Expect = 2e-32 Identities = 82/297 (27%), Positives = 148/297 (49%), Gaps = 9/297 (3%) Query: 33 SERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFI-IYLKNTLVADLI 91 +E+C ++T + ++F + Y + F+ ++ NTLALW+F+ S T ++L + VADL Sbjct: 20 AEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLS 79 Query: 92 MTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRN 151 L+LP +++ W CR + +FY MY I L I+ DRFL I+ P+++ Sbjct: 80 CVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKS 139 Query: 152 IFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNN 211 + L++P++A F+W + +++ ++S + + C L H +V+ Sbjct: 140 LKLRRPLYAHLACAFLW-VVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKA-SHHALVSL 197 Query: 212 ICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPF 271 F F FI + Y++I + S R+ +++ K + +V+A+F VCF P+ Sbjct: 198 AVAFTF--PFITTVTCYLLIIR----SLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPY 251 Query: 272 HFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKL 328 H R Y ++ C Q L +A T L + N +DP++Y F+ +KF L Sbjct: 252 HVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHAL 308 >gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] Length = 367 Score = 137 bits (344), Expect = 2e-32 Identities = 82/297 (27%), Positives = 148/297 (49%), Gaps = 9/297 (3%) Query: 33 SERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFI-IYLKNTLVADLI 91 +E+C ++T + ++F + Y + F+ ++ NTLALW+F+ S T ++L + VADL Sbjct: 48 AEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLS 107 Query: 92 MTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRN 151 L+LP +++ W CR + +FY MY I L I+ DRFL I+ P+++ Sbjct: 108 CVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKS 167 Query: 152 IFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNN 211 + L++P++A F+W + +++ ++S + + C L H +V+ Sbjct: 168 LKLRRPLYAHLACAFLW-VVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKA-SHHALVSL 225 Query: 212 ICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPF 271 F F FI + Y++I + S R+ +++ K + +V+A+F VCF P+ Sbjct: 226 AVAFTF--PFITTVTCYLLIIR----SLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPY 279 Query: 272 HFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKL 328 H R Y ++ C Q L +A T L + N +DP++Y F+ +KF L Sbjct: 280 HVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHAL 336 >gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] Length = 367 Score = 137 bits (344), Expect = 2e-32 Identities = 82/297 (27%), Positives = 148/297 (49%), Gaps = 9/297 (3%) Query: 33 SERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFI-IYLKNTLVADLI 91 +E+C ++T + ++F + Y + F+ ++ NTLALW+F+ S T ++L + VADL Sbjct: 48 AEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLS 107 Query: 92 MTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRN 151 L+LP +++ W CR + +FY MY I L I+ DRFL I+ P+++ Sbjct: 108 CVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKS 167 Query: 152 IFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNN 211 + L++P++A F+W + +++ ++S + + C L H +V+ Sbjct: 168 LKLRRPLYAHLACAFLW-VVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKA-SHHALVSL 225 Query: 212 ICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPF 271 F F FI + Y++I + S R+ +++ K + +V+A+F VCF P+ Sbjct: 226 AVAFTF--PFITTVTCYLLIIR----SLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPY 279 Query: 272 HFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKL 328 H R Y ++ C Q L +A T L + N +DP++Y F+ +KF L Sbjct: 280 HVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHAL 336 >gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens] Length = 337 Score = 128 bits (321), Expect = 9e-30 Identities = 90/302 (29%), Positives = 145/302 (48%), Gaps = 17/302 (5%) Query: 46 VFPALYTVVFLTGILLNTLALWVFVHI-PSSSTFIIYLKNTLVADLIMTLMLPFKILSDS 104 V+ LY+++ + G N L+V + S F +Y+ N VADL+ LP +++ Sbjct: 25 VYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYV 84 Query: 105 HLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVS 164 H W F+CR S+ Y +Y I + ++F R + I+ P++NI L A+ V Sbjct: 85 HKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVC 144 Query: 165 IFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMV-NNICQFI-FWTVFI 222 + IW F+ S P +++ + + KC K H +V + + F+ F F+ Sbjct: 145 VGIWIFVILTSSP-FLMAKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFV 203 Query: 223 LMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQ 282 +++V Y +I + +KS K+ ++KK G + VV A F V F P+H R + H Sbjct: 204 IIIVCYTMI---ILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHFL 260 Query: 283 TNNKTDC----RLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTA 338 N C R+Q + I TL LAA+N C DPL+Y F F ++L RK + Sbjct: 261 HNETKPCDSVLRMQKSVVI----TLSLAASNCCFDPLLYFFSGGNFRKRLSTF--RKHSL 314 Query: 339 SS 340 SS Sbjct: 315 SS 316 >gi|4506241 platelet-activating factor receptor [Homo sapiens] Length = 342 Score = 126 bits (317), Expect = 3e-29 Identities = 86/328 (26%), Positives = 161/328 (49%), Gaps = 25/328 (7%) Query: 39 DTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFI---IYLKNTLVADLIMTLM 95 D+ +FP +Y+++F+ G++ N LWVF + F I++ N +AD++ + Sbjct: 10 DSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLIT 69 Query: 96 LPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLK 155 LP I+ + W L F+C + +F+ Y + LG+I ++RF + RP++ Sbjct: 70 LPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQAN 129 Query: 156 KPVFAKTVSIFIWFFL-----FFISLPNTILSNKEATPSSVKKCAS--LKGPLGLKWHQM 208 ++S+ IW + +F+ L +T A +V +C KG + + + Sbjct: 130 TRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPV---LI 186 Query: 209 VNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCF 268 ++ F F+ VF+++L +VI + + + ++ + ++ V V+AVF +CF Sbjct: 187 IHIFIVFSFFLVFLIILFCNLVIIRTLL-MQPVQQQRNAEVKRRALWMVCTVLAVFIICF 245 Query: 269 APFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKF---- 324 P H ++P+T ++ + D + + A + TL L +TN +DP+IY FL KKF Sbjct: 246 VPHHVVQLPWTLAELGFQ-DSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHL 304 Query: 325 TEKLPCMQGRKTTASSQENHSSQTDNIT 352 TEK M+ SS++ + TD +T Sbjct: 305 TEKFYSMR------SSRKCSRATTDTVT 326 >gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] Length = 370 Score = 112 bits (279), Expect = 7e-25 Identities = 79/279 (28%), Positives = 132/279 (47%), Gaps = 7/279 (2%) Query: 49 ALYTVVFLTGILLNTLALWVFV-HIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLA 107 A+Y+VVF+ G++ N+++L+VF + S I++ N V+DL+ LPFKI + + Sbjct: 44 AVYSVVFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFN-R 102 Query: 108 PWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFI 167 W +C+ S F +Y ++ L I+ DRFL I+ P R+ ++ + V + Sbjct: 103 HWPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGV 162 Query: 168 WFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVF 227 W + + ++ S ++ +G W ++ I FI FI+ L+ Sbjct: 163 WILVLSGGISASLFSTTNVNNATT---TCFEGFSKRVWKTYLSKITIFIEVVGFIIPLIL 219 Query: 228 YVVIAKKVYDSYRK--SKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNN 285 V + V + RK + S+ N KK+ + V +AVF VCF P++ Y ++ Sbjct: 220 NVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQA 279 Query: 286 KTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKF 324 T+C L+ I TL LA N C DP IY F + F Sbjct: 280 ITNCFLERFAKIMYPITLCLATLNCCFDPFIYYFTLESF 318 >gi|14043066 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 111 bits (277), Expect = 1e-24 Identities = 84/314 (26%), Positives = 147/314 (46%), Gaps = 18/314 (5%) Query: 22 MNTTVMQGFNR-SERCPRDTR--IVQLVFPALYTVVFLTGILLNTLALWV-FVHIPSSST 77 +N++ G R + CP+ R + ++ P LY+++F+ GI N+L + V + ++ + Sbjct: 3 LNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTV 62 Query: 78 FIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLI 137 ++L N +ADL L LP + + W ++C+ +S +Y + LL + Sbjct: 63 ASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCL 122 Query: 138 AFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNK-EATPSSVKKCA- 195 + DR+L I+ P+++ + + AK I IW SLP I N +++ CA Sbjct: 123 SIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAF 182 Query: 196 -----SLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNN 250 + P+GL + NI F+F F+++L Y +I K + +Y K+K R N Sbjct: 183 HYESQNSTLPIGL---GLTKNILGFLF--PFLIILTSYTLIWKALKKAYEIQKNKPR--N 235 Query: 251 KKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNI 310 + + +V FF + P Q DCR+ + + A T+ +A N Sbjct: 236 DDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNN 295 Query: 311 CMDPLIYIFLCKKF 324 C++PL Y FL KKF Sbjct: 296 CLNPLFYGFLGKKF 309 >gi|14043064 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 111 bits (277), Expect = 1e-24 Identities = 84/314 (26%), Positives = 147/314 (46%), Gaps = 18/314 (5%) Query: 22 MNTTVMQGFNR-SERCPRDTR--IVQLVFPALYTVVFLTGILLNTLALWV-FVHIPSSST 77 +N++ G R + CP+ R + ++ P LY+++F+ GI N+L + V + ++ + Sbjct: 3 LNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTV 62 Query: 78 FIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLI 137 ++L N +ADL L LP + + W ++C+ +S +Y + LL + Sbjct: 63 ASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCL 122 Query: 138 AFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNK-EATPSSVKKCA- 195 + DR+L I+ P+++ + + AK I IW SLP I N +++ CA Sbjct: 123 SIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAF 182 Query: 196 -----SLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNN 250 + P+GL + NI F+F F+++L Y +I K + +Y K+K R N Sbjct: 183 HYESQNSTLPIGL---GLTKNILGFLF--PFLIILTSYTLIWKALKKAYEIQKNKPR--N 235 Query: 251 KKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNI 310 + + +V FF + P Q DCR+ + + A T+ +A N Sbjct: 236 DDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNN 295 Query: 311 CMDPLIYIFLCKKF 324 C++PL Y FL KKF Sbjct: 296 CLNPLFYGFLGKKF 309 >gi|14043062 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 111 bits (277), Expect = 1e-24 Identities = 84/314 (26%), Positives = 147/314 (46%), Gaps = 18/314 (5%) Query: 22 MNTTVMQGFNR-SERCPRDTR--IVQLVFPALYTVVFLTGILLNTLALWV-FVHIPSSST 77 +N++ G R + CP+ R + ++ P LY+++F+ GI N+L + V + ++ + Sbjct: 3 LNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTV 62 Query: 78 FIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLI 137 ++L N +ADL L LP + + W ++C+ +S +Y + LL + Sbjct: 63 ASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCL 122 Query: 138 AFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNK-EATPSSVKKCA- 195 + DR+L I+ P+++ + + AK I IW SLP I N +++ CA Sbjct: 123 SIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAF 182 Query: 196 -----SLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNN 250 + P+GL + NI F+F F+++L Y +I K + +Y K+K R N Sbjct: 183 HYESQNSTLPIGL---GLTKNILGFLF--PFLIILTSYTLIWKALKKAYEIQKNKPR--N 235 Query: 251 KKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNI 310 + + +V FF + P Q DCR+ + + A T+ +A N Sbjct: 236 DDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNN 295 Query: 311 CMDPLIYIFLCKKF 324 C++PL Y FL KKF Sbjct: 296 CLNPLFYGFLGKKF 309 >gi|6715583 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 111 bits (277), Expect = 1e-24 Identities = 84/314 (26%), Positives = 147/314 (46%), Gaps = 18/314 (5%) Query: 22 MNTTVMQGFNR-SERCPRDTR--IVQLVFPALYTVVFLTGILLNTLALWV-FVHIPSSST 77 +N++ G R + CP+ R + ++ P LY+++F+ GI N+L + V + ++ + Sbjct: 3 LNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTV 62 Query: 78 FIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLI 137 ++L N +ADL L LP + + W ++C+ +S +Y + LL + Sbjct: 63 ASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCL 122 Query: 138 AFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNK-EATPSSVKKCA- 195 + DR+L I+ P+++ + + AK I IW SLP I N +++ CA Sbjct: 123 SIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAF 182 Query: 196 -----SLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNN 250 + P+GL + NI F+F F+++L Y +I K + +Y K+K R N Sbjct: 183 HYESQNSTLPIGL---GLTKNILGFLF--PFLIILTSYTLIWKALKKAYEIQKNKPR--N 235 Query: 251 KKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNI 310 + + +V FF + P Q DCR+ + + A T+ +A N Sbjct: 236 DDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNN 295 Query: 311 CMDPLIYIFLCKKF 324 C++PL Y FL KKF Sbjct: 296 CLNPLFYGFLGKKF 309 >gi|4501997 angiotensin II receptor, type 1 [Homo sapiens] Length = 359 Score = 111 bits (277), Expect = 1e-24 Identities = 84/314 (26%), Positives = 147/314 (46%), Gaps = 18/314 (5%) Query: 22 MNTTVMQGFNR-SERCPRDTR--IVQLVFPALYTVVFLTGILLNTLALWV-FVHIPSSST 77 +N++ G R + CP+ R + ++ P LY+++F+ GI N+L + V + ++ + Sbjct: 3 LNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTV 62 Query: 78 FIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLI 137 ++L N +ADL L LP + + W ++C+ +S +Y + LL + Sbjct: 63 ASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCL 122 Query: 138 AFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNK-EATPSSVKKCA- 195 + DR+L I+ P+++ + + AK I IW SLP I N +++ CA Sbjct: 123 SIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAF 182 Query: 196 -----SLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNN 250 + P+GL + NI F+F F+++L Y +I K + +Y K+K R N Sbjct: 183 HYESQNSTLPIGL---GLTKNILGFLF--PFLIILTSYTLIWKALKKAYEIQKNKPR--N 235 Query: 251 KKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNI 310 + + +V FF + P Q DCR+ + + A T+ +A N Sbjct: 236 DDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNN 295 Query: 311 CMDPLIYIFLCKKF 324 C++PL Y FL KKF Sbjct: 296 CLNPLFYGFLGKKF 309 >gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 110 bits (275), Expect = 2e-24 Identities = 70/290 (24%), Positives = 136/290 (46%), Gaps = 5/290 (1%) Query: 33 SERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPS-SSTFIIYLKNTLVADLI 91 S C + ++ ++++VF+ G++ N +A+++F+ + + Y+ N ++DL+ Sbjct: 6 SSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLL 65 Query: 92 MTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRN 151 LPF+I + W +C+ S ++FY MY I+ L I+ DRFL I+ P ++ Sbjct: 66 FVFTLPFRIFYFT-TRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKS 124 Query: 152 IFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNN 211 L+ AK V +W + S P + + + ++ + P W ++ Sbjct: 125 KTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEAT-WKTYLSR 183 Query: 212 ICQFIFWTVFILMLVFYVVIAKKVYDSYRK--SKSKDRKNNKKLEGKVFVVVAVFFVCFA 269 I FI F + L+ V + V + K + S+ + N K+ +FV + +F CF Sbjct: 184 IVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFV 243 Query: 270 PFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIF 319 P++ + Y+ +T +C + + TL +A +N C DP++Y F Sbjct: 244 PYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYF 293 >gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 110 bits (275), Expect = 2e-24 Identities = 70/290 (24%), Positives = 136/290 (46%), Gaps = 5/290 (1%) Query: 33 SERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPS-SSTFIIYLKNTLVADLI 91 S C + ++ ++++VF+ G++ N +A+++F+ + + Y+ N ++DL+ Sbjct: 6 SSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLL 65 Query: 92 MTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRN 151 LPF+I + W +C+ S ++FY MY I+ L I+ DRFL I+ P ++ Sbjct: 66 FVFTLPFRIFYFT-TRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKS 124 Query: 152 IFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNN 211 L+ AK V +W + S P + + + ++ + P W ++ Sbjct: 125 KTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEAT-WKTYLSR 183 Query: 212 ICQFIFWTVFILMLVFYVVIAKKVYDSYRK--SKSKDRKNNKKLEGKVFVVVAVFFVCFA 269 I FI F + L+ V + V + K + S+ + N K+ +FV + +F CF Sbjct: 184 IVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFV 243 Query: 270 PFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIF 319 P++ + Y+ +T +C + + TL +A +N C DP++Y F Sbjct: 244 PYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYF 293 >gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sapiens] Length = 344 Score = 110 bits (275), Expect = 2e-24 Identities = 70/290 (24%), Positives = 136/290 (46%), Gaps = 5/290 (1%) Query: 33 SERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPS-SSTFIIYLKNTLVADLI 91 S C + ++ ++++VF+ G++ N +A+++F+ + + Y+ N ++DL+ Sbjct: 6 SSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLL 65 Query: 92 MTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRN 151 LPF+I + W +C+ S ++FY MY I+ L I+ DRFL I+ P ++ Sbjct: 66 FVFTLPFRIFYFT-TRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKS 124 Query: 152 IFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNN 211 L+ AK V +W + S P + + + ++ + P W ++ Sbjct: 125 KTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEAT-WKTYLSR 183 Query: 212 ICQFIFWTVFILMLVFYVVIAKKVYDSYRK--SKSKDRKNNKKLEGKVFVVVAVFFVCFA 269 I FI F + L+ V + V + K + S+ + N K+ +FV + +F CF Sbjct: 184 IVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFV 243 Query: 270 PFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIF 319 P++ + Y+ +T +C + + TL +A +N C DP++Y F Sbjct: 244 PYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYF 293 >gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] Length = 365 Score = 108 bits (269), Expect = 9e-24 Identities = 83/307 (27%), Positives = 143/307 (46%), Gaps = 19/307 (6%) Query: 45 LVFPALYTVVFLTGILLNTLALWVFV-HIPSSSTFIIYLKNTLVADLIMTLMLPFKILSD 103 ++ P Y VVF+ G+ LN LW+F+ + Y+ + ++D + L LP I Sbjct: 36 ILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYY 95 Query: 104 SHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTV 163 + W +C+F +FY +Y ++ L I+ R+L I PLR + +P A + Sbjct: 96 AAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLL 155 Query: 164 SIFIWFFLFFISLPNTIL---SNKEATPSSVKKCASLKGPLGLKWH-QMVNNICQFIFWT 219 + +W + +PN SNK T C P + + + +F Sbjct: 156 CLAVWLVVAGCLVPNLFFVTTSNKGTT----VLCHDTTRPEEFDHYVHFSSAVMGLLFGV 211 Query: 220 VFILMLVFYVVIAKKVYDSYRKS-KSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPY 278 ++ LV Y ++A+++Y S +S R + + + VV+ VF VCF PFH R Y Sbjct: 212 PCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLR---TIAVVLTVFAVCFVPFHITRTIY 268 Query: 279 THSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLP--CMQGR-- 334 ++ + DCR+ N + + + T LA+ N C+DP++Y+ K+ +L C G+ Sbjct: 269 YLARL-LEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQ 327 Query: 335 -KTTASS 340 +T ASS Sbjct: 328 PRTAASS 334 >gi|28872720 purinergic receptor P2Y2 [Homo sapiens] Length = 377 Score = 106 bits (265), Expect = 3e-23 Identities = 75/286 (26%), Positives = 135/286 (47%), Gaps = 6/286 (2%) Query: 35 RCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFV-HIPSSSTFIIYLKNTLVADLIMT 93 RC + ++ P Y VV + G+ LN +AL++F+ + + + Y+ + V+D + Sbjct: 24 RCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYA 83 Query: 94 LMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIF 153 LP + + W +C+ +FY +Y I+ L I+ R L ++RPLR++ Sbjct: 84 ASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLR 143 Query: 154 LKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGP-LGLKWHQMVNNI 212 + +A+ V+ +W + P A V C P L ++ + + Sbjct: 144 WGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRV-TCHDTSAPELFSRFVAYSSVM 202 Query: 213 CQFIFWTVFILMLVFYVVIAKKVY-DSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPF 271 +F F ++LV YV++A+++ +Y S R K + + VV+AVF +CF PF Sbjct: 203 LGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVR-TIAVVLAVFALCFLPF 261 Query: 272 HFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIY 317 H R Y +S + C N + +A + T LA+ N C+DP++Y Sbjct: 262 HVTRTLY-YSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLY 306 >gi|28872745 purinergic receptor P2Y2 [Homo sapiens] Length = 377 Score = 106 bits (265), Expect = 3e-23 Identities = 75/286 (26%), Positives = 135/286 (47%), Gaps = 6/286 (2%) Query: 35 RCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFV-HIPSSSTFIIYLKNTLVADLIMT 93 RC + ++ P Y VV + G+ LN +AL++F+ + + + Y+ + V+D + Sbjct: 24 RCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYA 83 Query: 94 LMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIF 153 LP + + W +C+ +FY +Y I+ L I+ R L ++RPLR++ Sbjct: 84 ASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLR 143 Query: 154 LKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGP-LGLKWHQMVNNI 212 + +A+ V+ +W + P A V C P L ++ + + Sbjct: 144 WGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRV-TCHDTSAPELFSRFVAYSSVM 202 Query: 213 CQFIFWTVFILMLVFYVVIAKKVY-DSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPF 271 +F F ++LV YV++A+++ +Y S R K + + VV+AVF +CF PF Sbjct: 203 LGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVR-TIAVVLAVFALCFLPF 261 Query: 272 HFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIY 317 H R Y +S + C N + +A + T LA+ N C+DP++Y Sbjct: 262 HVTRTLY-YSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLY 306 >gi|28872743 purinergic receptor P2Y2 [Homo sapiens] Length = 377 Score = 106 bits (265), Expect = 3e-23 Identities = 75/286 (26%), Positives = 135/286 (47%), Gaps = 6/286 (2%) Query: 35 RCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFV-HIPSSSTFIIYLKNTLVADLIMT 93 RC + ++ P Y VV + G+ LN +AL++F+ + + + Y+ + V+D + Sbjct: 24 RCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYA 83 Query: 94 LMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIF 153 LP + + W +C+ +FY +Y I+ L I+ R L ++RPLR++ Sbjct: 84 ASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLR 143 Query: 154 LKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGP-LGLKWHQMVNNI 212 + +A+ V+ +W + P A V C P L ++ + + Sbjct: 144 WGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRV-TCHDTSAPELFSRFVAYSSVM 202 Query: 213 CQFIFWTVFILMLVFYVVIAKKVY-DSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPF 271 +F F ++LV YV++A+++ +Y S R K + + VV+AVF +CF PF Sbjct: 203 LGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVR-TIAVVLAVFALCFLPF 261 Query: 272 HFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIY 317 H R Y +S + C N + +A + T LA+ N C+DP++Y Sbjct: 262 HVTRTLY-YSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLY 306 >gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens] Length = 346 Score = 106 bits (265), Expect = 3e-23 Identities = 86/326 (26%), Positives = 147/326 (45%), Gaps = 23/326 (7%) Query: 11 LSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFV 70 +S+ P +++ M N S C + + FP +Y ++F G+L N L+++VF+ Sbjct: 6 MSLQPSISVSEMEPNGTFSNNNSRNCTIEN-FKREFFPIVYLIIFFWGVLGNGLSIYVFL 64 Query: 71 HIPSSSTFI-IYLKNTLVADLIMTLMLPFKILSDSHL--APWQLRAFVCRFSSVIFYETM 127 ST + +++ N ++DL+ LPF+ +D +L + W CR S Y M Sbjct: 65 QPYKKSTSVNVFMLNLAISDLLFISTLPFR--ADYYLRGSNWIFGDLACRIMSYSLYVNM 122 Query: 128 YVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEAT 187 Y I L +++ RFL ++ P R + + A + IW + S+ +L + Sbjct: 123 YSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSI--MLLDSGSEQ 180 Query: 188 PSSVKKCASLKGPLGLKWHQMVNNI-----CQFIFWTVFILMLVFYVVIAKKVYDSYRKS 242 SV C L + Q +N I C F+T+ I L+ V+ K Sbjct: 181 NGSVTSCLEL-NLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLK-----VEVP 234 Query: 243 KSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETT 302 +S R +++K + + + +FF+CF P+H R + + RL L I T Sbjct: 235 ESGLRVSHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVI----T 290 Query: 303 LFLAATNICMDPLIYIFLCKKFTEKL 328 L LAA N C +PL+Y F + F ++L Sbjct: 291 LALAAANACFNPLLYYFAGENFKDRL 316 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.330 0.140 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,332,909 Number of Sequences: 37866 Number of extensions: 434963 Number of successful extensions: 2641 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 231 Number of HSP's successfully gapped in prelim test: 248 Number of HSP's that attempted gapping in prelim test: 1878 Number of HSP's gapped (non-prelim): 549 length of query: 354 length of database: 18,247,518 effective HSP length: 103 effective length of query: 251 effective length of database: 14,347,320 effective search space: 3601177320 effective search space used: 3601177320 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.