Guide to the Human Genome
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Search of human proteins with 194097356

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194097356 phosphomannomutase 1 [Homo sapiens]
         (262 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194097356 phosphomannomutase 1 [Homo sapiens]                      530   e-151
gi|4557839 phosphomannomutase 2 [Homo sapiens]                        343   1e-94
gi|26190608 synaptojanin 2 [Homo sapiens]                              33   0.33 
gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isofo...    29   4.8  
gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isofor...    29   4.8  
gi|156071472 CD2 molecule [Homo sapiens]                               28   8.1  
gi|55769518 inositol hexakisphosphate kinase 1 isoform 2 [Homo s...    28   8.1  
gi|23510335 inositol hexakisphosphate kinase 1 isoform 1 [Homo s...    28   8.1  

>gi|194097356 phosphomannomutase 1 [Homo sapiens]
          Length = 262

 Score =  530 bits (1366), Expect = e-151
 Identities = 262/262 (100%), Positives = 262/262 (100%)

Query: 1   MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIA 60
           MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIA
Sbjct: 1   MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIA 60

Query: 61  EQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLR 120
           EQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLR
Sbjct: 61  EQLGDGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLR 120

Query: 121 LPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLR 180
           LPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLR
Sbjct: 121 LPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLR 180

Query: 181 FSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSV 240
           FSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSV
Sbjct: 181 FSRGGMISFDVFPEGWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSV 240

Query: 241 VSPQDTVQRCREIFFPETAHEA 262
           VSPQDTVQRCREIFFPETAHEA
Sbjct: 241 VSPQDTVQRCREIFFPETAHEA 262


>gi|4557839 phosphomannomutase 2 [Homo sapiens]
          Length = 246

 Score =  343 bits (879), Expect = 1e-94
 Identities = 164/240 (68%), Positives = 199/240 (82%), Gaps = 2/240 (0%)

Query: 15  LCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIAEQLGDGDEVIEKFD 74
           LCLFDVDGTLT  RQKI  E+  FLQKLR +++IGVVGGSD+ K+ EQLG+  +V+EK+D
Sbjct: 8   LCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGN--DVVEKYD 65

Query: 75  YVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNG 134
           YVF ENG V YK G+LL +Q IQ+HLGE L+QDLIN+CLSY+A ++LPKKRGTFIEFRNG
Sbjct: 66  YVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNG 125

Query: 135 MLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPE 194
           MLN+SPIGRSC+ EERIEF ELDKKE IR+KFV  L+ EFAGKGL FS GG ISFDVFP+
Sbjct: 126 MLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPD 185

Query: 195 GWDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIF 254
           GWDKRYCL  ++ D + TI+FFG++T PGGND EIF DPRT+G+SV +P+DT + C  +F
Sbjct: 186 GWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLF 245


>gi|26190608 synaptojanin 2 [Homo sapiens]
          Length = 1496

 Score = 32.7 bits (73), Expect = 0.33
 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 2/63 (3%)

Query: 125  RGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKKEK--IREKFVEALKTEFAGKGLRFS 182
            R   I  R+ M  +SP   SC LEE  +F+ LD + +  I E   + L  EF   G+  S
Sbjct: 975  REEIIRKRDSMAPVSPTANSCLLEENFDFTSLDYESEGDILEDDEDYLVDEFNQPGVSDS 1034

Query: 183  RGG 185
              G
Sbjct: 1035 ELG 1037


>gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isoform
           b [Homo sapiens]
          Length = 1173

 Score = 28.9 bits (63), Expect = 4.8
 Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 14/102 (13%)

Query: 22  GTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIAEQLGD----------GDEVIE 71
           G L P    +    + FL +L+ R Q  +  GSD   + +++GD          G+ + E
Sbjct: 301 GRLFPCADDLLETHSHFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSGENGERMKE 360

Query: 72  KFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCL 113
           K+  VF         H +LL +   QN   + L++ + NF +
Sbjct: 361 KYG-VFCSGHNEAVSHYKLLLQ---QNKKFQNLIKKIGNFSI 398


>gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isoform a
           [Homo sapiens]
          Length = 1015

 Score = 28.9 bits (63), Expect = 4.8
 Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 14/102 (13%)

Query: 22  GTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIAEQLGD----------GDEVIE 71
           G L P    +    + FL +L+ R Q  +  GSD   + +++GD          G+ + E
Sbjct: 143 GRLFPCADDLLETHSHFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSGENGERMKE 202

Query: 72  KFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCL 113
           K+  VF         H +LL +   QN   + L++ + NF +
Sbjct: 203 KYG-VFCSGHNEAVSHYKLLLQ---QNKKFQNLIKKIGNFSI 240


>gi|156071472 CD2 molecule [Homo sapiens]
          Length = 351

 Score = 28.1 bits (61), Expect = 8.1
 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 15/111 (13%)

Query: 54  SDYCKIAEQLGDGDEVIEKFDYVFAENGTVQYKHGRL----LSKQTIQNHLGEELLQDLI 109
           SD  KIA+   + +   EK  Y   +NGT++ KH +     + K +I +  G+ +L+ + 
Sbjct: 63  SDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQDIYKVSIYDTKGKNVLEKI- 121

Query: 110 NFCLSYMALLRLPKKRGTFI------EFRNGM---LNISPIGRSCTLEERI 151
            F L     +  PK   T I      E  NG    LN+   G+   L +R+
Sbjct: 122 -FDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQDGKHLKLSQRV 171


>gi|55769518 inositol hexakisphosphate kinase 1 isoform 2 [Homo
           sapiens]
          Length = 276

 Score = 28.1 bits (61), Expect = 8.1
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 11/95 (11%)

Query: 87  HGRLLSKQTIQN------HLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNGMLNISP 140
           +GR LS +  +N      H G +L +DL    LS +  L+   +R     F +  L +  
Sbjct: 115 YGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIY 174

Query: 141 IGRSCTLEERIEFSELDKKEKIREKFVEALKTEFA 175
            G+ C  E     S LD++ ++R K ++ +  E A
Sbjct: 175 DGKECRAE-----SCLDRRSEMRLKHLDMVLPEVA 204


>gi|23510335 inositol hexakisphosphate kinase 1 isoform 1 [Homo
           sapiens]
          Length = 441

 Score = 28.1 bits (61), Expect = 8.1
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 11/95 (11%)

Query: 87  HGRLLSKQTIQN------HLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNGMLNISP 140
           +GR LS +  +N      H G +L +DL    LS +  L+   +R     F +  L +  
Sbjct: 280 YGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIY 339

Query: 141 IGRSCTLEERIEFSELDKKEKIREKFVEALKTEFA 175
            G+ C  E     S LD++ ++R K ++ +  E A
Sbjct: 340 DGKECRAE-----SCLDRRSEMRLKHLDMVLPEVA 369


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.140    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,970,587
Number of Sequences: 37866
Number of extensions: 442791
Number of successful extensions: 934
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 930
Number of HSP's gapped (non-prelim): 8
length of query: 262
length of database: 18,247,518
effective HSP length: 100
effective length of query: 162
effective length of database: 14,460,918
effective search space: 2342668716
effective search space used: 2342668716
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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