Guide to the Human Genome
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Search of human proteins with 190570158

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190570158 solute carrier family 14 (urea transporter),
member 1 isoform 2 [Homo sapiens]
         (389 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225690519 solute carrier family 14 (urea transporter), member...   793   0.0  
gi|190570158 solute carrier family 14 (urea transporter), member...   793   0.0  
gi|226371772 solute carrier family 14 (urea transporter), member...   793   0.0  
gi|226371768 solute carrier family 14 (urea transporter), member...   793   0.0  
gi|157694503 solute carrier family 14 (urea transporter), member...   516   e-146
gi|31542327 solute carrier family 22, member 16 [Homo sapiens]         30   3.7  
gi|218563730 chemokine (C-X-C motif) receptor 3 isoform B [Homo ...    29   6.3  
gi|4504099 chemokine (C-X-C motif) receptor 3 isoform A [Homo sa...    29   6.3  

>gi|225690519 solute carrier family 14 (urea transporter), member 1
           isoform 1 [Homo sapiens]
          Length = 445

 Score =  793 bits (2049), Expect = 0.0
 Identities = 389/389 (100%), Positives = 389/389 (100%)

Query: 1   MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID 60
           MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID
Sbjct: 57  MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID 116

Query: 61  WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG 120
           WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG
Sbjct: 117 WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG 176

Query: 121 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF 180
           LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF
Sbjct: 177 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF 236

Query: 181 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW 240
           NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW
Sbjct: 237 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW 296

Query: 241 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM 300
           TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM
Sbjct: 297 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM 356

Query: 301 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY 360
           FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY
Sbjct: 357 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY 416

Query: 361 KMPLSKVTYPEENRIFYLQAKKRMVESPL 389
           KMPLSKVTYPEENRIFYLQAKKRMVESPL
Sbjct: 417 KMPLSKVTYPEENRIFYLQAKKRMVESPL 445


>gi|190570158 solute carrier family 14 (urea transporter), member 1
           isoform 2 [Homo sapiens]
          Length = 389

 Score =  793 bits (2049), Expect = 0.0
 Identities = 389/389 (100%), Positives = 389/389 (100%)

Query: 1   MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID 60
           MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID
Sbjct: 1   MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID 60

Query: 61  WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG 120
           WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG
Sbjct: 61  WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG 120

Query: 121 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF 180
           LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF
Sbjct: 121 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF 180

Query: 181 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW 240
           NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW
Sbjct: 181 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW 240

Query: 241 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM 300
           TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM
Sbjct: 241 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM 300

Query: 301 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY 360
           FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY
Sbjct: 301 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY 360

Query: 361 KMPLSKVTYPEENRIFYLQAKKRMVESPL 389
           KMPLSKVTYPEENRIFYLQAKKRMVESPL
Sbjct: 361 KMPLSKVTYPEENRIFYLQAKKRMVESPL 389


>gi|226371772 solute carrier family 14 (urea transporter), member 1
           isoform 2 [Homo sapiens]
          Length = 389

 Score =  793 bits (2049), Expect = 0.0
 Identities = 389/389 (100%), Positives = 389/389 (100%)

Query: 1   MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID 60
           MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID
Sbjct: 1   MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID 60

Query: 61  WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG 120
           WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG
Sbjct: 61  WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG 120

Query: 121 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF 180
           LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF
Sbjct: 121 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF 180

Query: 181 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW 240
           NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW
Sbjct: 181 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW 240

Query: 241 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM 300
           TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM
Sbjct: 241 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM 300

Query: 301 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY 360
           FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY
Sbjct: 301 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY 360

Query: 361 KMPLSKVTYPEENRIFYLQAKKRMVESPL 389
           KMPLSKVTYPEENRIFYLQAKKRMVESPL
Sbjct: 361 KMPLSKVTYPEENRIFYLQAKKRMVESPL 389


>gi|226371768 solute carrier family 14 (urea transporter), member 1
           isoform 1 [Homo sapiens]
          Length = 445

 Score =  793 bits (2049), Expect = 0.0
 Identities = 389/389 (100%), Positives = 389/389 (100%)

Query: 1   MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID 60
           MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID
Sbjct: 57  MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID 116

Query: 61  WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG 120
           WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG
Sbjct: 117 WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG 176

Query: 121 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF 180
           LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF
Sbjct: 177 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF 236

Query: 181 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW 240
           NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW
Sbjct: 237 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW 296

Query: 241 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM 300
           TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM
Sbjct: 297 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM 356

Query: 301 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY 360
           FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY
Sbjct: 357 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY 416

Query: 361 KMPLSKVTYPEENRIFYLQAKKRMVESPL 389
           KMPLSKVTYPEENRIFYLQAKKRMVESPL
Sbjct: 417 KMPLSKVTYPEENRIFYLQAKKRMVESPL 445


>gi|157694503 solute carrier family 14 (urea transporter), member 2
           [Homo sapiens]
          Length = 920

 Score =  516 bits (1329), Expect = e-146
 Identities = 232/350 (66%), Positives = 290/350 (82%)

Query: 33  KALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNPWW 92
           KAL Y+TG+MKE    LKDK  V QF DW+LRG SQV+FVNNP+SGILI++GL +QNPWW
Sbjct: 555 KALSYITGEMKECGEGLKDKSPVFQFFDWVLRGTSQVMFVNNPLSGILIILGLFIQNPWW 614

Query: 93  ALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPVCA 152
           A++G LGT++STL AL+LSQD+S IA+G +GYN  LVG+LMAVFSDKGDY+WWLLLPV  
Sbjct: 615 AISGCLGTIMSTLTALILSQDKSAIAAGFHGYNGVLVGLLMAVFSDKGDYYWWLLLPVII 674

Query: 153 MSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAPNI 212
           MSM+CPI SSAL ++ SKWDLPVFTLPFN+ +++YL+ATGHYN FFP  L+ P +  PNI
Sbjct: 675 MSMSCPILSSALGTIFSKWDLPVFTLPFNITVTLYLAATGHYNLFFPTTLLQPASAMPNI 734

Query: 213 SWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAAGL 272
           +WS++    LL++IPVG+GQ+YGCDNPWTGGIFL A+ +SSPL+CLHAAIGS +G+ A L
Sbjct: 735 TWSEVQVPLLLRAIPVGIGQVYGCDNPWTGGIFLIALFISSPLICLHAAIGSTMGMLAAL 794

Query: 273 SLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFMAE 332
           +++ PF+ IYFGL GFNS+LACIA+GGMF  +TWQTHLLA+ CALF AYLG  +AN ++ 
Sbjct: 795 TIATPFDSIYFGLCGFNSTLACIAIGGMFYVITWQTHLLAIACALFAAYLGAALANMLSV 854

Query: 333 VGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKK 382
            GLP CTWPFCL+ L FL++TT N  IYK+PLSKVTYPE NRI+YL  ++
Sbjct: 855 FGLPPCTWPFCLSALTFLLLTTNNPAIYKLPLSKVTYPEANRIYYLSQER 904



 Score =  507 bits (1306), Expect = e-144
 Identities = 230/352 (65%), Positives = 291/352 (82%)

Query: 30  CFPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQN 89
           C  KA+GY+TGDMKE    LKDK + LQFIDW+LRG +QV+F+NNP+SG++I +GLL+QN
Sbjct: 90  CLSKAVGYLTGDMKEYRIWLKDKHLALQFIDWVLRGTAQVMFINNPLSGLIIFIGLLIQN 149

Query: 90  PWWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLP 149
           PWW +TG LGTVVSTL AL L QDRS IASGL+GYN  LVG+LMAVFS+K DY+WWLL P
Sbjct: 150 PWWTITGGLGTVVSTLTALALGQDRSAIASGLHGYNGMLVGLLMAVFSEKLDYYWWLLFP 209

Query: 150 VCAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTA 209
           V   +M+CP+ SSALNS+ SKWDLPVFTLPFN+A+++YL+ATGHYN FFP  LV P+++ 
Sbjct: 210 VTFTAMSCPVLSSALNSIFSKWDLPVFTLPFNIAVTLYLAATGHYNLFFPTTLVEPVSSV 269

Query: 210 PNISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIA 269
           PNI+W+++    LL++IPVGVGQ+YGCDNPWTGG+FL A+ +SSPL+CLHAAIGS++G+ 
Sbjct: 270 PNITWTEMEMPLLLQAIPVGVGQVYGCDNPWTGGVFLVALFISSPLICLHAAIGSIVGLL 329

Query: 270 AGLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANF 329
           A LS++ PFE IY GLW +N  L+CIA+GGMF ALTWQTHLLAL CALF AY+   ++N 
Sbjct: 330 AALSVATPFETIYTGLWSYNCVLSCIAIGGMFYALTWQTHLLALICALFCAYMEAAISNI 389

Query: 330 MAEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAK 381
           M+ VG+P  TW FCLAT++FL++TT N  I+++PLSKVTYPE NRI+YL  K
Sbjct: 390 MSVVGVPPGTWAFCLATIIFLLLTTNNPAIFRLPLSKVTYPEANRIYYLTVK 441


>gi|31542327 solute carrier family 22, member 16 [Homo sapiens]
          Length = 577

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 12/97 (12%)

Query: 285 LWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTA--YLGVGMANFMAEVGLPACTWP- 341
           LW  +SS+    +   F A+ + T + A       A  YL VG    M  +G+ + TW  
Sbjct: 185 LWATSSSMFLFGIAAAF-AVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWAS 243

Query: 342 ------FCLATLLFLI--MTTKNSNIYKMPLSKVTYP 370
                 F + TLL  +     +   +Y+M LS VT P
Sbjct: 244 VHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVP 280


>gi|218563730 chemokine (C-X-C motif) receptor 3 isoform B [Homo
           sapiens]
          Length = 415

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 28/97 (28%), Positives = 38/97 (39%), Gaps = 8/97 (8%)

Query: 250 LLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGL-WGFNSSLACIAMGGMFMALTWQT 308
           L S+    LH A+   L     L L+ P   +   + W F S L  +A  G    + +  
Sbjct: 132 LSSTDTFLLHLAVADTL-----LVLTLPLWAVDAAVQWVFGSGLCKVA--GALFNINFYA 184

Query: 309 HLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLA 345
             L L C  F  YL +  A  +   G PA     CLA
Sbjct: 185 GALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLA 221


>gi|4504099 chemokine (C-X-C motif) receptor 3 isoform A [Homo
           sapiens]
          Length = 368

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 28/97 (28%), Positives = 38/97 (39%), Gaps = 8/97 (8%)

Query: 250 LLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGL-WGFNSSLACIAMGGMFMALTWQT 308
           L S+    LH A+   L     L L+ P   +   + W F S L  +A  G    + +  
Sbjct: 85  LSSTDTFLLHLAVADTL-----LVLTLPLWAVDAAVQWVFGSGLCKVA--GALFNINFYA 137

Query: 309 HLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLA 345
             L L C  F  YL +  A  +   G PA     CLA
Sbjct: 138 GALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLA 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,893,049
Number of Sequences: 37866
Number of extensions: 574333
Number of successful extensions: 1532
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1512
Number of HSP's gapped (non-prelim): 11
length of query: 389
length of database: 18,247,518
effective HSP length: 104
effective length of query: 285
effective length of database: 14,309,454
effective search space: 4078194390
effective search space used: 4078194390
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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