Guide to the Human Genome
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Search of human proteins with 18860918

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18860918 xylulokinase [Homo sapiens]
         (536 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18860918 xylulokinase [Homo sapiens]                              1085   0.0  
gi|88196792 glycerol kinase 5 (putative) [Homo sapiens]                38   0.027
gi|74315356 carbohydrate kinase-like [Homo sapiens]                    33   0.86 
gi|46488923 astrotactin isoform 1 [Homo sapiens]                       31   3.3  
gi|46488921 astrotactin isoform 2 [Homo sapiens]                       31   3.3  
gi|194394158 nicotinate phosphoribosyltransferase domain contain...    30   5.5  
gi|21264330 mindbomb homolog 2 [Homo sapiens]                          29   9.5  

>gi|18860918 xylulokinase [Homo sapiens]
          Length = 536

 Score = 1085 bits (2806), Expect = 0.0
 Identities = 536/536 (100%), Positives = 536/536 (100%)

Query: 1   MAEHAPRRCCLGWDFSTQQVKVVAVDAELNVFYEESVHFDRDLPEFGTQGGVHVHKDGLT 60
           MAEHAPRRCCLGWDFSTQQVKVVAVDAELNVFYEESVHFDRDLPEFGTQGGVHVHKDGLT
Sbjct: 1   MAEHAPRRCCLGWDFSTQQVKVVAVDAELNVFYEESVHFDRDLPEFGTQGGVHVHKDGLT 60

Query: 61  VTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSIYWKAGAQQALTSLSPDLR 120
           VTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSIYWKAGAQQALTSLSPDLR
Sbjct: 61  VTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSIYWKAGAQQALTSLSPDLR 120

Query: 121 LHQQLQDCFSISDCPVWMDSSTTAQCRQLEAAVGGAQALSCLTGSRAYERFTGNQIAKIY 180
           LHQQLQDCFSISDCPVWMDSSTTAQCRQLEAAVGGAQALSCLTGSRAYERFTGNQIAKIY
Sbjct: 121 LHQQLQDCFSISDCPVWMDSSTTAQCRQLEAAVGGAQALSCLTGSRAYERFTGNQIAKIY 180

Query: 181 QQNPEAYSHTERISLVSSFAASLFLGSYSPIDYSDGSGMNLLQIQDKVWSQACLGACAPH 240
           QQNPEAYSHTERISLVSSFAASLFLGSYSPIDYSDGSGMNLLQIQDKVWSQACLGACAPH
Sbjct: 181 QQNPEAYSHTERISLVSSFAASLFLGSYSPIDYSDGSGMNLLQIQDKVWSQACLGACAPH 240

Query: 241 LEEKLSPPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDIAVSLG 300
           LEEKLSPPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDIAVSLG
Sbjct: 241 LEEKLSPPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDIAVSLG 300

Query: 301 TSDTLFLWLQEPMPALEGHIFCNPVDSQHYMALLCFKNGSLMREKIRNESVSRSWSDFSK 360
           TSDTLFLWLQEPMPALEGHIFCNPVDSQHYMALLCFKNGSLMREKIRNESVSRSWSDFSK
Sbjct: 301 TSDTLFLWLQEPMPALEGHIFCNPVDSQHYMALLCFKNGSLMREKIRNESVSRSWSDFSK 360

Query: 361 ALQSTEMGNGGNLGFYFDVMEITPEIIGRHRFNTENHKVAAFPGDVEVRALIEGQFMAKR 420
           ALQSTEMGNGGNLGFYFDVMEITPEIIGRHRFNTENHKVAAFPGDVEVRALIEGQFMAKR
Sbjct: 361 ALQSTEMGNGGNLGFYFDVMEITPEIIGRHRFNTENHKVAAFPGDVEVRALIEGQFMAKR 420

Query: 421 IHAEGLGYRVMSKTKILATGGASHNREILQVLADVFDAPVYVIDTANSACVGSAYRAFHG 480
           IHAEGLGYRVMSKTKILATGGASHNREILQVLADVFDAPVYVIDTANSACVGSAYRAFHG
Sbjct: 421 IHAEGLGYRVMSKTKILATGGASHNREILQVLADVFDAPVYVIDTANSACVGSAYRAFHG 480

Query: 481 LAGGTDVPFSEVVKLAPNPRLAATPSPGASQVYEALLPQYAKLEQRILSQTRGPPE 536
           LAGGTDVPFSEVVKLAPNPRLAATPSPGASQVYEALLPQYAKLEQRILSQTRGPPE
Sbjct: 481 LAGGTDVPFSEVVKLAPNPRLAATPSPGASQVYEALLPQYAKLEQRILSQTRGPPE 536


>gi|88196792 glycerol kinase 5 (putative) [Homo sapiens]
          Length = 529

 Score = 37.7 bits (86), Expect = 0.027
 Identities = 104/508 (20%), Positives = 182/508 (35%), Gaps = 77/508 (15%)

Query: 58  GLTVTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSIYWKAGAQQALTSLSP 117
           G     P ++W+Q + +I E +KA+G   +Q++ L  + Q+   I W         +   
Sbjct: 58  GWVEIDPDVLWIQFVAVIKEAVKAAGIQMNQIVGLGISTQRATFITWNKKTGNHFHNFI- 116

Query: 118 DLRLHQQLQDCFSISDCPVWMDSSTT----AQCRQLEAAVGGAQALSCLTGSRAYERFTG 173
                   QD  ++     W +S       + CR L       +  +    +   ++ T 
Sbjct: 117 ------SWQDLRAVELVKSWNNSLLMKIFHSSCRVLHFFTRSKRLFTASLFTFTTQQ-TS 169

Query: 174 NQIAKIYQQNPEAYSHTERI-----SLVSSFAASLFLGSYSPIDYSDGSGMNLLQIQDKV 228
            ++  I Q   E     E       ++ +     L  GS    D+S+ S   L       
Sbjct: 170 LRLVWILQNLTEVQKAVEEENCCFGTIDTWLLYKLTKGSVYATDFSNASTTGLFDPYKMC 229

Query: 229 WSQACLGACAPHLEEKLSPPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAG- 287
           WS       +  L   L PPV   S      S   + +G P    +VA   D  +++ G 
Sbjct: 230 WSGMITSLISIPL--SLLPPVRDTS--HNFGSVDEEIFGVP--IPIVALVADQQSAMFGE 283

Query: 288 MRLEEGDIAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDSQHYMALLCFKNGS----LMR 343
              + GD+ +++GT   L +     +    G  +           L+ +K G     L  
Sbjct: 284 CCFQTGDVKLTMGTGTFLDINTGNSLQQTTGGFY----------PLIGWKIGQEVVCLAE 333

Query: 344 EKIRNESVSRSWSD----FSKALQSTEMGNG--GNLGFYFDVMEITPEIIGRHRFNTENH 397
               +   +  W+     F+ A ++ +M      + G  F      P   G      +  
Sbjct: 334 SNAGDTGTAIKWAQQLDLFTDAAETEKMAKSLEDSEGVCF-----VPSFSGLQAPLNDPW 388

Query: 398 KVAAFPGDVE-------VRALIEG---------QFMAKRIHAEGLGYRVMSKTKILATGG 441
             A+F G          VRA++E          + M K IH        +   KI A GG
Sbjct: 389 ACASFMGLKPSTSKYHLVRAILESIAFRNKQLYEMMKKEIH--------IPVRKIRADGG 440

Query: 442 ASHNREILQVLADVFDAPVYVIDTANSACVGSAYRAFHGLAGGTDVPFSEVVKLAPNPRL 501
              N  ++Q+ +D+ +  +      + +C+G+A  A  GLA G      E+ KL  +  +
Sbjct: 441 VCKNGFVMQMTSDLINENIDRPADIDMSCLGAASLA--GLAVGFWTDKEELKKLRQS-EV 497

Query: 502 AATPSPGASQVYEALLPQYAKLEQRILS 529
              P     Q YE  L  +AK  +R ++
Sbjct: 498 VFKPQK-KCQEYEMSLENWAKAVKRSMN 524


>gi|74315356 carbohydrate kinase-like [Homo sapiens]
          Length = 478

 Score = 32.7 bits (73), Expect = 0.86
 Identities = 54/267 (20%), Positives = 95/267 (35%), Gaps = 43/267 (16%)

Query: 89  VLALSGAGQQHGSIYWKAGAQQALT--SLSPDLRLHQQLQDCFSISDCPVWMD----SST 142
           V+ +  +GQ HG ++WK G     T   ++P       + +  ++S    W D    S  
Sbjct: 84  VVGIGVSGQMHGVVFWKTGQGCEWTEGGITP-------VFEPRAVSHLVTWQDGRCSSEF 136

Query: 143 TAQCRQLEAAVGGAQALSCLTGSRAYERFTGNQIAKIYQQNPEAYSHTERISLVSSFAAS 202
            A   Q ++ +  A    C T            I  + +  PE     +    +  +  +
Sbjct: 137 LASLPQPKSHLSVATGFGCAT------------IFWLLKYRPEFLKSYDAAGTIHDYVVA 184

Query: 203 LFLGSYSPI-DYSDGSGMNLLQIQDKVWSQACLGACA--PHLEEKLSPPVPSCSVVGAIS 259
           +  G   P+    + +       Q + W+   L +     HL   ++ P    SV G  S
Sbjct: 185 MLCGLPRPLMSDQNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEP---GSVAGRTS 241

Query: 260 SYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTL-------FLWLQEP 312
             +   +  P G +V    GD  AS+     +  D  +++ TS  L       F   Q P
Sbjct: 242 HMW---FEIPKGTQVGVALGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTP 298

Query: 313 MPALEGHIFCNPVDSQHYMALLCFKNG 339
            P      F  P  ++ Y+ +    NG
Sbjct: 299 DPTAPVAYF--PYFNRTYLGVAASLNG 323


>gi|46488923 astrotactin isoform 1 [Homo sapiens]
          Length = 1294

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 20/59 (33%), Positives = 27/59 (45%)

Query: 320 IFCNPVDSQHYMALLCFKNGSLMREKIRNESVSRSWSDFSKALQSTEMGNGGNLGFYFD 378
           I  +PVDS H  A L     S  R++I N++ + S     +    TE  N   L FY D
Sbjct: 306 IATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAFLNPEGDSGTEAENDPQLTFYTD 364


>gi|46488921 astrotactin isoform 2 [Homo sapiens]
          Length = 1216

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 20/59 (33%), Positives = 27/59 (45%)

Query: 320 IFCNPVDSQHYMALLCFKNGSLMREKIRNESVSRSWSDFSKALQSTEMGNGGNLGFYFD 378
           I  +PVDS H  A L     S  R++I N++ + S     +    TE  N   L FY D
Sbjct: 306 IATSPVDSNHQQATLLSHTSSSQRKRINNKARAGSAFLNPEGDSGTEAENDPQLTFYTD 364


>gi|194394158 nicotinate phosphoribosyltransferase domain containing
           1 [Homo sapiens]
          Length = 538

 Score = 30.0 bits (66), Expect = 5.5
 Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 17/117 (14%)

Query: 194 SLVSSFAASLFLGSYSPID------YSDGSGMNLLQIQDKVW-SQAC----LGACAPHLE 242
           +L  SF  S F GS  P D        +G G++L   + +VW  Q C    LG   PH  
Sbjct: 210 TLAHSFVTS-FSGSEVPPDPMLAPAAGEGPGVDLAA-KAQVWLEQVCAHLGLGVQEPHPG 267

Query: 243 EKLSPPVPSCSVV----GAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDI 295
           E+ +    + +      G + +Y V R G P    V    G+      G+RL+ GD+
Sbjct: 268 ERAAFVAYALAFPRAFQGLLDTYSVWRSGLPNFLAVALALGELGYRAVGVRLDSGDL 324


>gi|21264330 mindbomb homolog 2 [Homo sapiens]
          Length = 1013

 Score = 29.3 bits (64), Expect = 9.5
 Identities = 46/187 (24%), Positives = 77/187 (41%), Gaps = 30/187 (16%)

Query: 371 GNLGFYFDVMEITPEIIGRHRFNTENHKVAAFPGDVE-VRALIEGQFMAKRIHAEG---L 426
           GN     D++   PE +          +VAA+ G VE +R L++ +        EG   L
Sbjct: 501 GNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTAL 560

Query: 427 GYRVMSK----TKILATGG------------ASH---NREILQVLADVFD--APVYVIDT 465
            Y  +      T++L + G            A H    R  L+V+  + +    V + D 
Sbjct: 561 HYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDA 620

Query: 466 ANSACVGSAYRAFHGLAGGTDVPFSEVVKLAPNPRLAATPSPGASQVYEALLPQYAKLEQ 525
            +   + SA  A  G +G       EV+   PN  + AT S G + ++ A L  +A   +
Sbjct: 621 HSDTPLHSAISAGTGASG-----IVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVR 675

Query: 526 RILSQTR 532
           +IL++ R
Sbjct: 676 KILARAR 682


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,452,306
Number of Sequences: 37866
Number of extensions: 965158
Number of successful extensions: 2090
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2086
Number of HSP's gapped (non-prelim): 8
length of query: 536
length of database: 18,247,518
effective HSP length: 107
effective length of query: 429
effective length of database: 14,195,856
effective search space: 6090022224
effective search space used: 6090022224
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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