Search of human proteins with 10190672

Search of human proteins with 10190672

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10190672 fibroblast growth factor 22 precursor [Homo
sapiens]
         (170 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]      355   1e-98
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]       174   4e-44
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]        137   4e-33
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]        123   7e-29
gi|4503691 fibroblast growth factor 16 [Homo sapiens]                 122   1e-28
gi|9789947 fibroblast growth factor 20 [Homo sapiens]                 121   3e-28
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]        118   3e-27
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]         93   1e-19
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo...    93   1e-19
gi|4758362 fibroblast growth factor 11 [Homo sapiens]                  92   2e-19
gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]       89   2e-18
gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]       88   3e-18
gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]       88   4e-18
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]      87   7e-18
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr...    82   3e-16
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot...    82   3e-16
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr...    82   3e-16
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr...    82   3e-16
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]      80   1e-15
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]        80   1e-15
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]       79   1e-15
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]      79   2e-15
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]      79   2e-15
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]      79   2e-15
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]        78   3e-15
gi|153285461 fibroblast growth factor 2 [Homo sapiens]                 76   2e-14
gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens]        60   9e-10
gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]        50   9e-07
gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens]        49   2e-06
gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo...    49   3e-06

>gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]
          Length = 170

 Score =  355 bits (911), Expect = 1e-98
 Identities = 170/170 (100%), Positives = 170/170 (100%)

Query: 1   MRRRLWLGLAWLLLARAPDAAGTPSASRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGR 60
           MRRRLWLGLAWLLLARAPDAAGTPSASRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGR
Sbjct: 1   MRRRLWLGLAWLLLARAPDAAGTPSASRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGR 60

Query: 61  VQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIE 120
           VQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIE
Sbjct: 61  VQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIE 120

Query: 121 ENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS 170
           ENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS
Sbjct: 121 ENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS 170


>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
          Length = 208

 Score =  174 bits (440), Expect = 4e-44
 Identities = 79/145 (54%), Positives = 112/145 (77%)

Query: 25  SASRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVV 84
           SA R  RSY HL+GDVRWR+LFS T +FL+++  G+V GT+  +   SILEI SV +GVV
Sbjct: 62  SAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVV 121

Query: 85  VIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRRGQPMFLALD 144
            +KA++S +Y+AMN++G+LYGS+ +  DC+ +ERIEENG+NTYAS  W+  G+ M++AL+
Sbjct: 122 AVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVALN 181

Query: 145 RRGGPRPGGRTRRYHLSAHFLPVLV 169
            +G PR G +TRR + SAHFLP++V
Sbjct: 182 GKGAPRRGQKTRRKNTSAHFLPMVV 206


>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
          Length = 194

 Score =  137 bits (345), Expect = 4e-33
 Identities = 68/147 (46%), Positives = 99/147 (67%), Gaps = 1/147 (0%)

Query: 25  SASRGPRSYPHLEG-DVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGV 83
           S  R  RSY ++EG D+R RRLF  T ++LR+D  G+V+GT+      +I+EIR+V VG+
Sbjct: 48  SPERHTRSYDYMEGGDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGI 107

Query: 84  VVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRRGQPMFLAL 143
           V IK V S FY+AMN+ G+LY  +    DC F+E I EN +NTYAS +W   G  MF+AL
Sbjct: 108 VAIKGVESEFYLAMNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHNGGEMFVAL 167

Query: 144 DRRGGPRPGGRTRRYHLSAHFLPVLVS 170
           +++G P  G +T++   +AHFLP+ ++
Sbjct: 168 NQKGIPVRGKKTKKEQKTAHFLPMAIT 194


>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
          Length = 208

 Score =  123 bits (309), Expect = 7e-29
 Identities = 67/152 (44%), Positives = 93/152 (61%), Gaps = 7/152 (4%)

Query: 19  DAAGTPSASRGPR--SYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEI 76
           +A G P   RGP      HL+G +R R+L+  T F L + P G +QGTR  H +  ILE 
Sbjct: 41  EAGGLP---RGPAVTDLDHLKGILRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEF 97

Query: 77  RSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRR-- 134
            S+ VG+V I+ V SG Y+ MN +G LYGS   T +C FRE+ EEN +NTY+S  ++   
Sbjct: 98  ISIAVGLVSIRGVDSGLYLGMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVD 157

Query: 135 RGQPMFLALDRRGGPRPGGRTRRYHLSAHFLP 166
            G+  ++AL++ G PR G RT+R+    HFLP
Sbjct: 158 TGRRYYVALNKDGTPREGTRTKRHQKFTHFLP 189


>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
          Length = 207

 Score =  122 bits (306), Expect = 1e-28
 Identities = 62/139 (44%), Positives = 87/139 (62%), Gaps = 2/139 (1%)

Query: 30  PRSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAV 89
           P  + HL+G +R R+L+  T F L + P G V GTR  H +  ILE  S+ VG++ I+ V
Sbjct: 50  PTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGV 109

Query: 90  SSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRRG--QPMFLALDRRG 147
            SG Y+ MN RG LYGS+  T +C FRE+ EEN +NTYAS  ++     +  ++AL++ G
Sbjct: 110 DSGLYLGMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDG 169

Query: 148 GPRPGGRTRRYHLSAHFLP 166
            PR G RT+R+    HFLP
Sbjct: 170 SPREGYRTKRHQKFTHFLP 188


>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
          Length = 211

 Score =  121 bits (303), Expect = 3e-28
 Identities = 68/151 (45%), Positives = 92/151 (60%), Gaps = 4/151 (2%)

Query: 20  AAGTPSASRGPRS--YPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIR 77
           +A   SA  GP +    HL G +R R+L+  T F L++ P G VQGTR  H    ILE  
Sbjct: 42  SAAERSARGGPGAAQLAHLHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFI 101

Query: 78  SVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRR--R 135
           SV VG+V I+ V SG Y+ MN +G LYGS   T +C FRE+ EEN +NTY+S  ++    
Sbjct: 102 SVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDT 161

Query: 136 GQPMFLALDRRGGPRPGGRTRRYHLSAHFLP 166
           G+  F+AL++ G PR G R++R+    HFLP
Sbjct: 162 GRRYFVALNKDGTPRDGARSKRHQKFTHFLP 192


>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
          Length = 239

 Score =  118 bits (295), Expect = 3e-27
 Identities = 75/182 (41%), Positives = 105/182 (57%), Gaps = 24/182 (13%)

Query: 7   LGLAWLLLARAPDAAGTPSASRGPRS----------YPHLEGDVRWRRLFSSTHFFLRVD 56
           +GL WLLL    +  G P+A  G R           Y HL G  R R+L+ +T + L++ 
Sbjct: 1   MGLIWLLLLSLLEP-GWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLH 59

Query: 57  PGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFR 116
           P GRV G+   +   SILEI +V VG+V I+ + SG Y+AMN+RGRLY S  Y+ +C F 
Sbjct: 60  PSGRVNGSL-ENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFV 118

Query: 117 ERIEENGHNTYASQRWR-------RRGQP-----MFLALDRRGGPRPGGRTRRYHLSAHF 164
           ERI E G+NTYAS+ +R        R QP      +++++ +G PR G +TRR   S+ F
Sbjct: 119 ERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLF 178

Query: 165 LP 166
           LP
Sbjct: 179 LP 180


>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
          Length = 206

 Score = 93.2 bits (230), Expect = 1e-19
 Identities = 63/167 (37%), Positives = 88/167 (52%), Gaps = 7/167 (4%)

Query: 4   RLWLGLAWLLLARAPDAAGTPSASRGPRSYPHLEGDVRWRRLFSSTH--FFLRVDPGGRV 61
           R W  L  L LAR P AA    A+    +  +L G  R RRL+ +    F L+  P GR+
Sbjct: 45  RRWESLVALSLARLPVAAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRI 104

Query: 62  QGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEE 121
            G      +DS+LE+  V  GVV I  V+S F+VAM+ +G+LYGS  +T +C F+E +  
Sbjct: 105 GGAH-ADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLP 163

Query: 122 NGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVL 168
           N +N Y S ++      MF+AL + G  + G R        HFLP L
Sbjct: 164 NNYNAYESYKY----PGMFIALSKNGKTKKGNRVSPTMKVTHFLPRL 206


>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
           sapiens]
          Length = 268

 Score = 93.2 bits (230), Expect = 1e-19
 Identities = 58/160 (36%), Positives = 92/160 (57%), Gaps = 14/160 (8%)

Query: 20  AAGTPSASRGPRSYPHLEGDVRW----RRLFS-----STHFFLRVDPGGRVQGTRWRHGQ 70
           A+ +P+AS G +     +   +W    RR  S        F L++ P G+V G+      
Sbjct: 59  ASSSPAASLGSQGSGLEQSSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSH-EANM 117

Query: 71  DSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYAS- 129
            S+LEI +V  G+V I+ V S  ++AM+++G+L+ S  +T DC+FRER +EN +NTYAS 
Sbjct: 118 LSVLEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFTDDCKFRERFQENSYNTYASA 177

Query: 130 -QRWRRRGQPMFLALDRRGGPRPG--GRTRRYHLSAHFLP 166
             R  + G+  ++AL++RG  + G   R +  H+S HFLP
Sbjct: 178 IHRTEKTGREWYVALNKRGKAKRGCSPRVKPQHISTHFLP 217


>gi|4758362 fibroblast growth factor 11 [Homo sapiens]
          Length = 225

 Score = 92.4 bits (228), Expect = 2e-19
 Identities = 59/161 (36%), Positives = 87/161 (54%), Gaps = 7/161 (4%)

Query: 12  LLLARAPDAAGTPSA-SRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQ 70
           +LL++     G P+   RGP   P L+G V   +LF    F+L+ +P G +QGT      
Sbjct: 45  ILLSKVRLCGGRPARPDRGPE--PQLKGIVT--KLFCRQGFYLQANPDGSIQGTPEDTSS 100

Query: 71  DSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYAS- 129
            +   +  V + VV I++   G Y+AMN  G LY S  +T +CRF+E + EN +  YAS 
Sbjct: 101 FTHFNLIPVGLRVVTIQSAKLGHYMAMNAEGLLYSSPHFTAECRFKECVFENYYVLYASA 160

Query: 130 -QRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLV 169
             R RR G+  +L LD+ G    G R ++   +AHFLP L+
Sbjct: 161 LYRQRRSGRAWYLGLDKEGQVMKGNRVKKTKAAAHFLPKLL 201


>gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]
          Length = 243

 Score = 89.0 bits (219), Expect = 2e-18
 Identities = 49/138 (35%), Positives = 80/138 (57%), Gaps = 4/138 (2%)

Query: 31  RSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVS 90
           R  P L+G V   RLFS   +FL++ P G + GT+  +   ++  +  V + VV I+ V 
Sbjct: 65  RPEPQLKGIVT--RLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK 122

Query: 91  SGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGG 148
           +  YVAMN  G LY S ++T +C+F+E + EN +  Y+S  +R++  G+  FL L++ G 
Sbjct: 123 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ 182

Query: 149 PRPGGRTRRYHLSAHFLP 166
              G R ++   S+HF+P
Sbjct: 183 IMKGNRVKKTKPSSHFVP 200


>gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]
          Length = 181

 Score = 88.2 bits (217), Expect = 3e-18
 Identities = 48/135 (35%), Positives = 79/135 (58%), Gaps = 4/135 (2%)

Query: 34  PHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGF 93
           P L+G V   RLFS   +FL++ P G + GT+  +   ++  +  V + VV I+ V +  
Sbjct: 6   PQLKGIVT--RLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASL 63

Query: 94  YVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGGPRP 151
           YVAMN  G LY S ++T +C+F+E + EN +  Y+S  +R++  G+  FL L++ G    
Sbjct: 64  YVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMK 123

Query: 152 GGRTRRYHLSAHFLP 166
           G R ++   S+HF+P
Sbjct: 124 GNRVKKTKPSSHFVP 138


>gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]
          Length = 247

 Score = 87.8 bits (216), Expect = 4e-18
 Identities = 48/138 (34%), Positives = 79/138 (57%), Gaps = 4/138 (2%)

Query: 31  RSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVS 90
           R  P L+G V   RL+    ++L++ P G + GT+      ++  +  V + VV I+ V 
Sbjct: 63  RQDPQLKGIVT--RLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK 120

Query: 91  SGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGG 148
           +G Y+AMN  G LY S L+T +C+F+E + EN +  Y+S  +R++  G+  FL L++ G 
Sbjct: 121 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ 180

Query: 149 PRPGGRTRRYHLSAHFLP 166
              G R ++   +AHFLP
Sbjct: 181 AMKGNRVKKTKPAAHFLP 198


>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
          Length = 252

 Score = 87.0 bits (214), Expect = 7e-18
 Identities = 47/135 (34%), Positives = 78/135 (57%), Gaps = 4/135 (2%)

Query: 34  PHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGF 93
           P L+G V   RL+    ++L++ P G + GT+      ++  +  V + VV I+ V +G 
Sbjct: 71  PQLKGIVT--RLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGL 128

Query: 94  YVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGGPRP 151
           Y+AMN  G LY S L+T +C+F+E + EN +  Y+S  +R++  G+  FL L++ G    
Sbjct: 129 YIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMK 188

Query: 152 GGRTRRYHLSAHFLP 166
           G R ++   +AHFLP
Sbjct: 189 GNRVKKTKPAAHFLP 203


>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
           proprotein [Homo sapiens]
          Length = 155

 Score = 81.6 bits (200), Expect = 3e-16
 Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 2/119 (1%)

Query: 52  FLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTV 111
           FLR+ P G V GTR R  Q   L++ +  VG V IK+  +G Y+AM+  G LYGS+    
Sbjct: 37  FLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNE 96

Query: 112 DCRFRERIEENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS 170
           +C F ER+EEN +NTY S++   +    F+ L + G  + G RT     +  FLP+ VS
Sbjct: 97  ECLFLERLEENHYNTYISKKHAEKN--WFVGLKKNGSCKRGPRTHYGQKAILFLPLPVS 153


>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
           [Homo sapiens]
          Length = 155

 Score = 81.6 bits (200), Expect = 3e-16
 Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 2/119 (1%)

Query: 52  FLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTV 111
           FLR+ P G V GTR R  Q   L++ +  VG V IK+  +G Y+AM+  G LYGS+    
Sbjct: 37  FLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNE 96

Query: 112 DCRFRERIEENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS 170
           +C F ER+EEN +NTY S++   +    F+ L + G  + G RT     +  FLP+ VS
Sbjct: 97  ECLFLERLEENHYNTYISKKHAEKN--WFVGLKKNGSCKRGPRTHYGQKAILFLPLPVS 153


>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
           proprotein [Homo sapiens]
          Length = 155

 Score = 81.6 bits (200), Expect = 3e-16
 Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 2/119 (1%)

Query: 52  FLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTV 111
           FLR+ P G V GTR R  Q   L++ +  VG V IK+  +G Y+AM+  G LYGS+    
Sbjct: 37  FLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNE 96

Query: 112 DCRFRERIEENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS 170
           +C F ER+EEN +NTY S++   +    F+ L + G  + G RT     +  FLP+ VS
Sbjct: 97  ECLFLERLEENHYNTYISKKHAEKN--WFVGLKKNGSCKRGPRTHYGQKAILFLPLPVS 153


>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
           proprotein [Homo sapiens]
          Length = 155

 Score = 81.6 bits (200), Expect = 3e-16
 Identities = 48/119 (40%), Positives = 68/119 (57%), Gaps = 2/119 (1%)

Query: 52  FLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTV 111
           FLR+ P G V GTR R  Q   L++ +  VG V IK+  +G Y+AM+  G LYGS+    
Sbjct: 37  FLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNE 96

Query: 112 DCRFRERIEENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS 170
           +C F ER+EEN +NTY S++   +    F+ L + G  + G RT     +  FLP+ VS
Sbjct: 97  ECLFLERLEENHYNTYISKKHAEKN--WFVGLKKNGSCKRGPRTHYGQKAILFLPLPVS 153


>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
          Length = 199

 Score = 79.7 bits (195), Expect = 1e-15
 Identities = 45/145 (31%), Positives = 78/145 (53%), Gaps = 4/145 (2%)

Query: 24  PSASRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGV 83
           P   +     P L+G V   +L+S   + L++   G + GT+      ++  +  V + V
Sbjct: 8   PKEEKDASKEPQLKGIVT--KLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRV 65

Query: 84  VVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFL 141
           V I+ V +  Y+AMN  G LY S L+T +C+F+E + EN + TY+S  +R++  G+  +L
Sbjct: 66  VAIQGVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYL 125

Query: 142 ALDRRGGPRPGGRTRRYHLSAHFLP 166
            L++ G    G   ++   +AHFLP
Sbjct: 126 GLNKEGEIMKGNHVKKNKPAAHFLP 150


>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
          Length = 245

 Score = 79.7 bits (195), Expect = 1e-15
 Identities = 46/141 (32%), Positives = 78/141 (55%), Gaps = 4/141 (2%)

Query: 28  RGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIK 87
           R  R  P L+G V   +L+S   + L++   G + GT+      ++  +  V + VV I+
Sbjct: 58  RRRRPEPQLKGIVT--KLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQ 115

Query: 88  AVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDR 145
            V +  Y+AMN  G LY S L+T +C+F+E + EN + TY+S  +R++  G+  +L L++
Sbjct: 116 GVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNK 175

Query: 146 RGGPRPGGRTRRYHLSAHFLP 166
            G    G   ++   +AHFLP
Sbjct: 176 EGEIMKGNHVKKNKPAAHFLP 196


>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
          Length = 192

 Score = 79.3 bits (194), Expect = 1e-15
 Identities = 45/137 (32%), Positives = 77/137 (56%), Gaps = 4/137 (2%)

Query: 32  SYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSS 91
           S P L+G V   +L+S   + L++   G + GT+      ++  +  V + VV I+ V +
Sbjct: 9   SEPQLKGIVT--KLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQT 66

Query: 92  GFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGGP 149
             Y+AMN  G LY S L+T +C+F+E + EN + TY+S  +R++  G+  +L L++ G  
Sbjct: 67  KLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEI 126

Query: 150 RPGGRTRRYHLSAHFLP 166
             G   ++   +AHFLP
Sbjct: 127 MKGNHVKKNKPAAHFLP 143


>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
          Length = 226

 Score = 78.6 bits (192), Expect = 2e-15
 Identities = 44/135 (32%), Positives = 76/135 (56%), Gaps = 4/135 (2%)

Query: 34  PHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGF 93
           P L+G V   +L+S   + L++   G + GT+      ++  +  V + VV I+ V +  
Sbjct: 45  PQLKGIVT--KLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKL 102

Query: 94  YVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGGPRP 151
           Y+AMN  G LY S L+T +C+F+E + EN + TY+S  +R++  G+  +L L++ G    
Sbjct: 103 YLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMK 162

Query: 152 GGRTRRYHLSAHFLP 166
           G   ++   +AHFLP
Sbjct: 163 GNHVKKNKPAAHFLP 177


>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
          Length = 226

 Score = 78.6 bits (192), Expect = 2e-15
 Identities = 44/135 (32%), Positives = 76/135 (56%), Gaps = 4/135 (2%)

Query: 34  PHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGF 93
           P L+G V   +L+S   + L++   G + GT+      ++  +  V + VV I+ V +  
Sbjct: 45  PQLKGIVT--KLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKL 102

Query: 94  YVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGGPRP 151
           Y+AMN  G LY S L+T +C+F+E + EN + TY+S  +R++  G+  +L L++ G    
Sbjct: 103 YLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMK 162

Query: 152 GGRTRRYHLSAHFLP 166
           G   ++   +AHFLP
Sbjct: 163 GNHVKKNKPAAHFLP 177


>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
          Length = 255

 Score = 78.6 bits (192), Expect = 2e-15
 Identities = 44/135 (32%), Positives = 76/135 (56%), Gaps = 4/135 (2%)

Query: 34  PHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGF 93
           P L+G V   +L+S   + L++   G + GT+      ++  +  V + VV I+ V +  
Sbjct: 74  PQLKGIVT--KLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKL 131

Query: 94  YVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGGPRP 151
           Y+AMN  G LY S L+T +C+F+E + EN + TY+S  +R++  G+  +L L++ G    
Sbjct: 132 YLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMK 191

Query: 152 GGRTRRYHLSAHFLP 166
           G   ++   +AHFLP
Sbjct: 192 GNHVKKNKPAAHFLP 206


>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
          Length = 208

 Score = 78.2 bits (191), Expect = 3e-15
 Identities = 49/134 (36%), Positives = 71/134 (52%), Gaps = 7/134 (5%)

Query: 35  HLEGDVRWRRLFSSTH--FFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSG 92
           +L G  R RRL+ +    F L+V P GR+ GT       S+LEI +V  GVV +  V S 
Sbjct: 78  YLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTH-EENPYSLLEISTVERGVVSLFGVRSA 136

Query: 93  FYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRRGQPMFLALDRRGGPRPG 152
            +VAMN +GRLY +  +  +C+FRE +  N +N Y S  +    Q  ++AL + G  + G
Sbjct: 137 LFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLY----QGTYIALSKYGRVKRG 192

Query: 153 GRTRRYHLSAHFLP 166
            +        HFLP
Sbjct: 193 SKVSPIMTVTHFLP 206


>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
          Length = 288

 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 44/117 (37%), Positives = 65/117 (55%), Gaps = 4/117 (3%)

Query: 51  FFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYT 110
           FFLR+ P GRV G R +      L++++   GVV IK V +  Y+AM   GRL  S+  T
Sbjct: 172 FFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVT 231

Query: 111 VDCRFRERIEENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPV 167
            +C F ER+E N +NTY S+++       ++AL R G  + G +T     +  FLP+
Sbjct: 232 DECFFFERLESNNYNTYRSRKY----TSWYVALKRTGQYKLGSKTGPGQKAILFLPM 284


>gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens]
          Length = 216

 Score = 60.1 bits (144), Expect = 9e-10
 Identities = 52/166 (31%), Positives = 80/166 (48%), Gaps = 15/166 (9%)

Query: 11  WLLLARAPDAAGTPSA--SRGPRSYPHLEGDVRWRRLFSS-----THFFLRVDPGGRVQG 63
           W+L       AG P A    GP  +      +R R L++S     +  FLR+   G V  
Sbjct: 11  WILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDC 70

Query: 64  TRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTV-DCRFRERIEEN 122
            R +    S+LEI++V +  V IK V S  Y+ M   G++ G   Y+  DC F E I  +
Sbjct: 71  ARGQSAH-SLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPD 129

Query: 123 GHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVL 168
           G+N Y S++ R    P+ L+  ++   R   + R +   +HFLP+L
Sbjct: 130 GYNVYRSEKHR---LPVSLSSAKQ---RQLYKNRGFLPLSHFLPML 169


>gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]
          Length = 209

 Score = 50.1 bits (118), Expect = 9e-07
 Identities = 50/162 (30%), Positives = 75/162 (46%), Gaps = 21/162 (12%)

Query: 5   LWLG-LAWLLLARAPDAAGTPSASRGPRSYPHLE--GDVRWRRLFSS----THFFLRVDP 57
           LW+  LA LLL       G   A   P S P L+  G VR R L++     T   L +  
Sbjct: 13  LWVSVLAGLLL-------GACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIRE 65

Query: 58  GGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVD-CRFR 116
            G V G       +S+L+++++  GV+ I  V +  ++     G LYGS  +  + C FR
Sbjct: 66  DGTVGGAA-DQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFR 124

Query: 117 ERIEENGHNTYASQRWRRRGQPMFLALDR--RGGPRPGGRTR 156
           E + E+G+N Y S+     G P+ L  ++     P P G  R
Sbjct: 125 ELLLEDGYNVYQSE---AHGLPLHLPGNKSPHRDPAPRGPAR 163


>gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens]
          Length = 216

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 29/83 (34%), Positives = 43/83 (51%), Gaps = 5/83 (6%)

Query: 84  VVIKAVSSGFYVAMNRRGRLYGSRL-YTVDCRFRERIEENGHNTYASQRWRRRGQPMFLA 142
           V IK   S  Y+ MN+RG+L G     + DC F E + EN +  + + R     +  F+A
Sbjct: 97  VRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARH----EGWFMA 152

Query: 143 LDRRGGPRPGGRTRRYHLSAHFL 165
             R+G PR   R+R+    AHF+
Sbjct: 153 FTRQGRPRQASRSRQNQREAHFI 175


>gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo
           sapiens]
          Length = 204

 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 5/83 (6%)

Query: 84  VVIKAVSSGFYVAMNRRGRLYG-SRLYTVDCRFRERIEENGHNTYASQRWRRRGQPMFLA 142
           V ++   +G Y+ MN++G+L   S     DC F E + EN +    + ++    +  ++A
Sbjct: 86  VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY----EGWYMA 141

Query: 143 LDRRGGPRPGGRTRRYHLSAHFL 165
             R+G PR G +TR++    HF+
Sbjct: 142 FTRKGRPRKGSKTRQHQREVHFM 164


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.462 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,469,243
Number of Sequences: 37866
Number of extensions: 333753
Number of successful extensions: 1134
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1070
Number of HSP's gapped (non-prelim): 43
length of query: 170
length of database: 18,247,518
effective HSP length: 95
effective length of query: 75
effective length of database: 14,650,248
effective search space: 1098768600
effective search space used: 1098768600
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.