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Search of human proteins with 11136630
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11136630 fibroblast growth factor 12 isoform 1 [Homo
sapiens]
(243 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens] 489 e-138
gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens] 363 e-101
gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens] 350 5e-97
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens] 320 5e-88
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens] 286 1e-77
gi|4758362 fibroblast growth factor 11 [Homo sapiens] 272 2e-73
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens] 264 5e-71
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens] 264 5e-71
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens] 264 5e-71
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens] 264 5e-71
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens] 264 5e-71
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens] 119 3e-27
gi|9789947 fibroblast growth factor 20 [Homo sapiens] 115 4e-26
gi|4503691 fibroblast growth factor 16 [Homo sapiens] 114 8e-26
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens] 97 2e-20
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo... 94 1e-19
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens] 92 4e-19
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens] 92 4e-19
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens] 90 2e-18
gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens] 89 3e-18
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens] 86 4e-17
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr... 80 2e-15
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot... 80 2e-15
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr... 80 2e-15
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr... 80 2e-15
gi|153285461 fibroblast growth factor 2 [Homo sapiens] 71 7e-13
gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens] 50 2e-06
gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens] 49 3e-06
gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens] 49 4e-06
gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens] 48 7e-06
>gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]
Length = 243
Score = 489 bits (1258), Expect = e-138
Identities = 243/243 (100%), Positives = 243/243 (100%)
Query: 1 MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKR 60
MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKR
Sbjct: 1 MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKR 60
Query: 61 PVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQG 120
PVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQG
Sbjct: 61 PVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQG 120
Query: 121 VKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKE 180
VKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKE
Sbjct: 121 VKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKE 180
Query: 181 GQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQ 240
GQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQ
Sbjct: 181 GQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQ 240
Query: 241 DST 243
DST
Sbjct: 241 DST 243
>gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]
Length = 181
Score = 363 bits (931), Expect = e-101
Identities = 177/177 (100%), Positives = 177/177 (100%)
Query: 67 EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 126
EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY
Sbjct: 5 EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 64
Query: 127 VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 186
VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG
Sbjct: 65 VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 124
Query: 187 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST 243
NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST
Sbjct: 125 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST 181
>gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]
Length = 247
Score = 350 bits (899), Expect = 5e-97
Identities = 178/248 (71%), Positives = 210/248 (84%), Gaps = 7/248 (2%)
Query: 1 MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKR 60
MAAAIAS LIRQKRQARE + DR SAS+RRSSPSK+ R LC +++ +FSKVR +KR
Sbjct: 1 MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKN-RGLCNGNLVDIFSKVRIFGLKKR 59
Query: 61 PVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQG 120
+RR+ +PQLKGIVTRL+ +QGY+LQMHPDG +DGTKD++++ TLFNLIPVGLRVVAIQG
Sbjct: 60 RLRRQ-DPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQG 118
Query: 121 VKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKE 180
VK LY+AMNGEGYLY S++FTPECKFKESVFENYYVIYSS LYRQQESGRAWFLGLNKE
Sbjct: 119 VKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKE 178
Query: 181 GQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGE---KQG--RSRKSSGTPTMNGG 235
GQ MKGNRVKKTKP++HF+PKP+EV MYREPSLH++GE K G S+ +S + MNGG
Sbjct: 179 GQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGG 238
Query: 236 KVVNQDST 243
K VN+ T
Sbjct: 239 KPVNKSKT 246
>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
Length = 245
Score = 320 bits (821), Expect = 5e-88
Identities = 165/251 (65%), Positives = 203/251 (80%), Gaps = 15/251 (5%)
Query: 1 MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKR 60
MAAAIASSLIRQKRQARE ++ +A K SSPSK G++ C+++ L VFS+V+ +KR
Sbjct: 1 MAAAIASSLIRQKRQARER--EKSNACKCVSSPSK-GKTSCDKNKLNVFSRVKLFGSKKR 57
Query: 61 PVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQG 120
RRRPEPQLKGIVT+L+S+QGY LQ+ DGTIDGTKDE+S YTLFNLIPVGLRVVAIQG
Sbjct: 58 R-RRRPEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQG 116
Query: 121 VKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKE 180
V+ LY+AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKE
Sbjct: 117 VQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKE 176
Query: 181 GQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------M 232
G+IMKGN VKK KP++HF+PKP++V MY+EPSLH++ E SR SGTPT +
Sbjct: 177 GEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVL 233
Query: 233 NGGKVVNQDST 243
NGGK ++ + +
Sbjct: 234 NGGKSMSHNES 244
>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
Length = 252
Score = 286 bits (731), Expect = 1e-77
Identities = 138/194 (71%), Positives = 162/194 (83%), Gaps = 5/194 (2%)
Query: 55 CSGRKRPVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLR 114
C + + +PQLKGIVTRL+ +QGY+LQMHPDG +DGTKD++++ TLFNLIPVGLR
Sbjct: 58 CGKSLKKNKNPTDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLR 117
Query: 115 VVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWF 174
VVAIQGVK LY+AMNGEGYLY S++FTPECKFKESVFENYYVIYSS LYRQQESGRAWF
Sbjct: 118 VVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWF 177
Query: 175 LGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGE---KQG--RSRKSSGT 229
LGLNKEGQ MKGNRVKKTKP++HF+PKP+EV MYREPSLH++GE K G S+ +S +
Sbjct: 178 LGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSAS 237
Query: 230 PTMNGGKVVNQDST 243
MNGGK VN+ T
Sbjct: 238 AIMNGGKPVNKSKT 251
>gi|4758362 fibroblast growth factor 11 [Homo sapiens]
Length = 225
Score = 272 bits (695), Expect = 2e-73
Identities = 133/216 (61%), Positives = 167/216 (77%), Gaps = 1/216 (0%)
Query: 3 AAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKRPV 62
AA+ASSLIRQKR+ RE R +++RR P + +SLC++ +L + SKVR C GR
Sbjct: 2 AALASSLIRQKREVREPGGSRPVSAQRRVCP-RGTKSLCQKQLLILLSKVRLCGGRPARP 60
Query: 63 RRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK 122
R PEPQLKGIVT+LF +QG++LQ +PDG+I GT ++ S +T FNLIPVGLRVV IQ K
Sbjct: 61 DRGPEPQLKGIVTKLFCRQGFYLQANPDGSIQGTPEDTSSFTHFNLIPVGLRVVTIQSAK 120
Query: 123 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ 182
Y+AMN EG LYSS FT EC+FKE VFENYYV+Y+S LYRQ+ SGRAW+LGL+KEGQ
Sbjct: 121 LGHYMAMNAEGLLYSSPHFTAECRFKECVFENYYVLYASALYRQRRSGRAWYLGLDKEGQ 180
Query: 183 IMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGE 218
+MKGNRVKKTK ++HF+PK +EV MY+EPSLH + E
Sbjct: 181 VMKGNRVKKTKAAAHFLPKLLEVAMYQEPSLHSVPE 216
>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 264 bits (675), Expect = 5e-71
Identities = 127/185 (68%), Positives = 154/185 (83%), Gaps = 11/185 (5%)
Query: 67 EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 126
EPQLKGIVT+L+S+QGY LQ+ DGTIDGTKDE+S YTLFNLIPVGLRVVAIQGV+ LY
Sbjct: 44 EPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLY 103
Query: 127 VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 186
+AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKEG+IMKG
Sbjct: 104 LAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKG 163
Query: 187 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------MNGGKVV 238
N VKK KP++HF+PKP++V MY+EPSLH++ E SR SGTPT +NGGK +
Sbjct: 164 NHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVLNGGKSM 220
Query: 239 NQDST 243
+ + +
Sbjct: 221 SHNES 225
>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 264 bits (675), Expect = 5e-71
Identities = 127/185 (68%), Positives = 154/185 (83%), Gaps = 11/185 (5%)
Query: 67 EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 126
EPQLKGIVT+L+S+QGY LQ+ DGTIDGTKDE+S YTLFNLIPVGLRVVAIQGV+ LY
Sbjct: 44 EPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLY 103
Query: 127 VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 186
+AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKEG+IMKG
Sbjct: 104 LAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKG 163
Query: 187 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------MNGGKVV 238
N VKK KP++HF+PKP++V MY+EPSLH++ E SR SGTPT +NGGK +
Sbjct: 164 NHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVLNGGKSM 220
Query: 239 NQDST 243
+ + +
Sbjct: 221 SHNES 225
>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
Length = 255
Score = 264 bits (675), Expect = 5e-71
Identities = 127/185 (68%), Positives = 154/185 (83%), Gaps = 11/185 (5%)
Query: 67 EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 126
EPQLKGIVT+L+S+QGY LQ+ DGTIDGTKDE+S YTLFNLIPVGLRVVAIQGV+ LY
Sbjct: 73 EPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLY 132
Query: 127 VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 186
+AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKEG+IMKG
Sbjct: 133 LAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKG 192
Query: 187 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------MNGGKVV 238
N VKK KP++HF+PKP++V MY+EPSLH++ E SR SGTPT +NGGK +
Sbjct: 193 NHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVLNGGKSM 249
Query: 239 NQDST 243
+ + +
Sbjct: 250 SHNES 254
>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
Length = 199
Score = 264 bits (675), Expect = 5e-71
Identities = 127/185 (68%), Positives = 154/185 (83%), Gaps = 11/185 (5%)
Query: 67 EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 126
EPQLKGIVT+L+S+QGY LQ+ DGTIDGTKDE+S YTLFNLIPVGLRVVAIQGV+ LY
Sbjct: 17 EPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLY 76
Query: 127 VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 186
+AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKEG+IMKG
Sbjct: 77 LAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKG 136
Query: 187 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------MNGGKVV 238
N VKK KP++HF+PKP++V MY+EPSLH++ E SR SGTPT +NGGK +
Sbjct: 137 NHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVLNGGKSM 193
Query: 239 NQDST 243
+ + +
Sbjct: 194 SHNES 198
>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
Length = 192
Score = 264 bits (675), Expect = 5e-71
Identities = 127/185 (68%), Positives = 154/185 (83%), Gaps = 11/185 (5%)
Query: 67 EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 126
EPQLKGIVT+L+S+QGY LQ+ DGTIDGTKDE+S YTLFNLIPVGLRVVAIQGV+ LY
Sbjct: 10 EPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLY 69
Query: 127 VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 186
+AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKEG+IMKG
Sbjct: 70 LAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKG 129
Query: 187 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------MNGGKVV 238
N VKK KP++HF+PKP++V MY+EPSLH++ E SR SGTPT +NGGK +
Sbjct: 130 NHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVLNGGKSM 186
Query: 239 NQDST 243
+ + +
Sbjct: 187 SHNES 191
>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
Length = 208
Score = 119 bits (297), Expect = 3e-27
Identities = 54/137 (39%), Positives = 92/137 (67%), Gaps = 2/137 (1%)
Query: 70 LKGIVTR--LFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYV 127
LKGI+ R L+ + G+ L++ P+GTI GT+ ++S + + I + + +V+I+GV + LY+
Sbjct: 57 LKGILRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYL 116
Query: 128 AMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGN 187
MN +G LY S+ T EC F+E EN+Y YSS LY+ ++GR +++ LNK+G +G
Sbjct: 117 GMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGT 176
Query: 188 RVKKTKPSSHFVPKPIE 204
R K+ + +HF+P+P++
Sbjct: 177 RTKRHQKFTHFLPRPVD 193
>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
Length = 211
Score = 115 bits (287), Expect = 4e-26
Identities = 54/137 (39%), Positives = 90/137 (65%), Gaps = 2/137 (1%)
Query: 70 LKGIVTR--LFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYV 127
L GI+ R L+ + G+ LQ+ PDG++ GT+ ++S + + I V + +V+I+GV + LY+
Sbjct: 60 LHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYL 119
Query: 128 AMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGN 187
MN +G LY S+ T EC F+E EN+Y YSS +Y+ ++GR +F+ LNK+G G
Sbjct: 120 GMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGA 179
Query: 188 RVKKTKPSSHFVPKPIE 204
R K+ + +HF+P+P++
Sbjct: 180 RSKRHQKFTHFLPRPVD 196
>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
Length = 207
Score = 114 bits (285), Expect = 8e-26
Identities = 52/137 (37%), Positives = 90/137 (65%), Gaps = 2/137 (1%)
Query: 70 LKGIVTR--LFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYV 127
LKGI+ R L+ + G+ L++ P+GT+ GT+ ++S + + I + + +++I+GV + LY+
Sbjct: 56 LKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYL 115
Query: 128 AMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGN 187
MN G LY S T EC F+E EN+Y Y+STLY+ +S R +++ LNK+G +G
Sbjct: 116 GMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGY 175
Query: 188 RVKKTKPSSHFVPKPIE 204
R K+ + +HF+P+P++
Sbjct: 176 RTKRHQKFTHFLPRPVD 192
>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
Length = 208
Score = 96.7 bits (239), Expect = 2e-20
Identities = 46/125 (36%), Positives = 76/125 (60%), Gaps = 2/125 (1%)
Query: 76 RLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYL 135
+LFS YFL++ +G + GTK EN Y++ + V + VVA++ + ++ Y+AMN +G L
Sbjct: 81 KLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKL 140
Query: 136 YSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPS 195
Y S F +CK KE + EN Y Y+S + Q +GR ++ LN +G +G + ++ S
Sbjct: 141 YGSKEFNNDCKLKERIEENGYNTYAS--FNWQHNGRQMYVALNGKGAPRRGQKTRRKNTS 198
Query: 196 SHFVP 200
+HF+P
Sbjct: 199 AHFLP 203
>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
sapiens]
Length = 268
Score = 94.0 bits (232), Expect = 1e-19
Identities = 45/122 (36%), Positives = 80/122 (65%), Gaps = 3/122 (2%)
Query: 82 GYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVF 141
G+ LQ++PDG ++G+ + N ++ + V +V I+GV ++ ++AM+ +G L++S F
Sbjct: 98 GFHLQIYPDGKVNGSHEANM-LSVLEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKF 156
Query: 142 TPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG--NRVKKTKPSSHFV 199
T +CKF+E EN Y Y+S ++R +++GR W++ LNK G+ +G RVK S+HF+
Sbjct: 157 TDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCSPRVKPQHISTHFL 216
Query: 200 PK 201
P+
Sbjct: 217 PR 218
>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
Length = 194
Score = 92.0 bits (227), Expect = 4e-19
Identities = 44/130 (33%), Positives = 79/130 (60%), Gaps = 2/130 (1%)
Query: 74 VTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEG 133
V RLF + ++L++ G + GT++ ++Y + + V + +VAI+GV++ Y+AMN EG
Sbjct: 66 VRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESEFYLAMNKEG 125
Query: 134 YLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTK 193
LY+ +C FKE + EN+Y Y+S + +G F+ LN++G ++G + KK +
Sbjct: 126 KLYAKKECNEDCNFKELILENHYNTYASA--KWTHNGGEMFVALNQKGIPVRGKKTKKEQ 183
Query: 194 PSSHFVPKPI 203
++HF+P I
Sbjct: 184 KTAHFLPMAI 193
>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
Length = 239
Score = 92.0 bits (227), Expect = 4e-19
Identities = 47/139 (33%), Positives = 84/139 (60%), Gaps = 11/139 (7%)
Query: 76 RLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYL 135
+L+ Y LQ+HP G ++G+ ENS Y++ + V + +VAI+G+ + Y+AMN G L
Sbjct: 47 KLYCATKYHLQLHPSGRVNGSL-ENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRL 105
Query: 136 YSSDVFTPECKFKESVFENYYVIYSSTLY----------RQQESGRAWFLGLNKEGQIMK 185
Y+S+ ++ EC+F E + E Y Y+S LY RQ + R W++ +N +G+ +
Sbjct: 106 YASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRR 165
Query: 186 GNRVKKTKPSSHFVPKPIE 204
G + ++T+ SS F+P+ ++
Sbjct: 166 GFKTRRTQKSSLFLPRVLD 184
>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
Length = 208
Score = 90.1 bits (222), Expect = 2e-18
Identities = 46/120 (38%), Positives = 75/120 (62%), Gaps = 7/120 (5%)
Query: 82 GYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVF 141
G+ LQ+ PDG I GT +EN Y+L + V VV++ GV+++L+VAMN +G LY++ F
Sbjct: 95 GFHLQVLPDGRISGTHEENP-YSLLEISTVERGVVSLFGVRSALFVAMNSKGRLYATPSF 153
Query: 142 TPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPK 201
ECKF+E++ N Y Y S LY + ++ L+K G++ +G++V +HF+P+
Sbjct: 154 QEECKFRETLLPNNYNAYESDLY------QGTYIALSKYGRVKRGSKVSPIMTVTHFLPR 207
>gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]
Length = 170
Score = 89.0 bits (219), Expect = 3e-18
Identities = 49/138 (35%), Positives = 80/138 (57%), Gaps = 4/138 (2%)
Query: 65 RPEPQLKGIVT--RLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK 122
R P L+G V RLFS +FL++ P G + GT+ + ++ + V + VV I+ V
Sbjct: 31 RSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVS 90
Query: 123 ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ 182
+ YVAMN G LY S ++T +C+F+E + EN + Y+S +R++ G+ FL L++ G
Sbjct: 91 SGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGG 148
Query: 183 IMKGNRVKKTKPSSHFVP 200
G R ++ S+HF+P
Sbjct: 149 PRPGGRTRRYHLSAHFLP 166
>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
Length = 206
Score = 85.5 bits (210), Expect = 4e-17
Identities = 50/120 (41%), Positives = 65/120 (54%), Gaps = 7/120 (5%)
Query: 82 GYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVF 141
G+ LQ PDG I G + D +L L PV VV+I GV + +VAM+ +G LY S F
Sbjct: 93 GFHLQALPDGRIGGAHADTRD-SLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFF 151
Query: 142 TPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPK 201
T EC FKE + N Y Y S Y F+ L+K G+ KGNRV T +HF+P+
Sbjct: 152 TDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTMKVTHFLPR 205
>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 80.1 bits (196), Expect = 2e-15
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 4/125 (3%)
Query: 79 SQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSS 138
S G+FL++ PDGT+DGT+D + + L + V I+ + Y+AM+ +G LY S
Sbjct: 32 SNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS 91
Query: 139 DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHF 198
EC F E + EN+Y Y S ++ + + WF+GL K G +G R + + F
Sbjct: 92 QTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILF 147
Query: 199 VPKPI 203
+P P+
Sbjct: 148 LPLPV 152
>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
[Homo sapiens]
Length = 155
Score = 80.1 bits (196), Expect = 2e-15
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 4/125 (3%)
Query: 79 SQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSS 138
S G+FL++ PDGT+DGT+D + + L + V I+ + Y+AM+ +G LY S
Sbjct: 32 SNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS 91
Query: 139 DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHF 198
EC F E + EN+Y Y S ++ + + WF+GL K G +G R + + F
Sbjct: 92 QTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILF 147
Query: 199 VPKPI 203
+P P+
Sbjct: 148 LPLPV 152
>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 80.1 bits (196), Expect = 2e-15
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 4/125 (3%)
Query: 79 SQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSS 138
S G+FL++ PDGT+DGT+D + + L + V I+ + Y+AM+ +G LY S
Sbjct: 32 SNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS 91
Query: 139 DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHF 198
EC F E + EN+Y Y S ++ + + WF+GL K G +G R + + F
Sbjct: 92 QTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILF 147
Query: 199 VPKPI 203
+P P+
Sbjct: 148 LPLPV 152
>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 80.1 bits (196), Expect = 2e-15
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 4/125 (3%)
Query: 79 SQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSS 138
S G+FL++ PDGT+DGT+D + + L + V I+ + Y+AM+ +G LY S
Sbjct: 32 SNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS 91
Query: 139 DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHF 198
EC F E + EN+Y Y S ++ + + WF+GL K G +G R + + F
Sbjct: 92 QTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILF 147
Query: 199 VPKPI 203
+P P+
Sbjct: 148 LPLPV 152
>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
Length = 288
Score = 71.2 bits (173), Expect = 7e-13
Identities = 39/119 (32%), Positives = 64/119 (53%), Gaps = 6/119 (5%)
Query: 82 GYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVF 141
G+FL++HPDG +DG ++++ + L VV+I+GV A+ Y+AM +G L +S
Sbjct: 171 GFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCV 230
Query: 142 TPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVP 200
T EC F E + N Y Y S Y +W++ L + GQ G++ + + F+P
Sbjct: 231 TDECFFFERLESNNYNTYRSRKY------TSWYVALKRTGQYKLGSKTGPGQKAILFLP 283
>gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens]
Length = 216
Score = 49.7 bits (117), Expect = 2e-06
Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 10/118 (8%)
Query: 84 FLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTP 143
FL++ DG +D + +++ ++L + V LR VAI+GV + Y+ M +G + ++
Sbjct: 59 FLRIRADGVVDCARGQSA-HSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSE 117
Query: 144 E-CKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVP 200
E C F+E + + Y +Y S +R S L K+ Q+ K + P SHF+P
Sbjct: 118 EDCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLP 167
>gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens]
Length = 251
Score = 49.3 bits (116), Expect = 3e-06
Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 79 SQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSS 138
++ Y LQ+H +G +DG + Y+ + V I GV + Y+ M+ G ++ S
Sbjct: 47 ARNSYHLQIHKNGHVDGAPHQTI-YSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGS 105
Query: 139 DVFTPE-CKFKESVFENYYVIYSSTLYR----QQESGRAWFLGLN 178
F PE C+F+ EN Y +Y S Y + RA+ G+N
Sbjct: 106 HYFDPENCRFQHQTLENGYDVYHSPQYHFLVSLGRAKRAFLPGMN 150
>gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]
Length = 209
Score = 48.9 bits (115), Expect = 4e-06
Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 2/78 (2%)
Query: 85 LQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPE 144
L++ DGT+ G D++ + +L L + V+ I GVK S ++ +G LY S F PE
Sbjct: 61 LEIREDGTVGGAADQSPE-SLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119
Query: 145 -CKFKESVFENYYVIYSS 161
C F+E + E+ Y +Y S
Sbjct: 120 ACSFRELLLEDGYNVYQS 137
>gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens]
Length = 207
Score = 48.1 bits (113), Expect = 7e-06
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%)
Query: 116 VAIQGVKASLYVAMNGEGYLYSS-DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWF 174
V I+G + Y+ MN +G L D + EC F E V EN Y S Y W+
Sbjct: 97 VRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYS------GWY 150
Query: 175 LGLNKEGQIMKGNRVKKTKPSSHFVPK 201
+G K+G+ KG + ++ + HF+ +
Sbjct: 151 VGFTKKGRPRKGPKTRENQQDVHFMKR 177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,653,799
Number of Sequences: 37866
Number of extensions: 454625
Number of successful extensions: 1040
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 969
Number of HSP's gapped (non-prelim): 54
length of query: 243
length of database: 18,247,518
effective HSP length: 99
effective length of query: 144
effective length of database: 14,498,784
effective search space: 2087824896
effective search space used: 2087824896
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.