Guide to the Human Genome
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Search of human proteins with 166706911

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166706911 interferon-induced, hepatitis C-associated
microtubular aggregate protein [Homo sapiens]
         (444 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166706911 interferon-induced, hepatitis C-associated microtub...   893   0.0  
gi|166706909 interferon-induced protein 44-like [Homo sapiens]        352   3e-97
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]       30   3.4  
gi|56119214 GTPase, IMAP family member 6 [Homo sapiens]                30   4.4  
gi|8922873 GTPase, IMAP family member 4 [Homo sapiens]                 29   7.5  
gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo s...    29   9.8  
gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo sa...    29   9.8  

>gi|166706911 interferon-induced, hepatitis C-associated
           microtubular aggregate protein [Homo sapiens]
          Length = 444

 Score =  893 bits (2307), Expect = 0.0
 Identities = 444/444 (100%), Positives = 444/444 (100%)

Query: 1   MAVTTRLTWLHEKILQNHFGGKRLSLLYKGSVHGFRNGVLLDRCCNQGPTLTVIYSEDHI 60
           MAVTTRLTWLHEKILQNHFGGKRLSLLYKGSVHGFRNGVLLDRCCNQGPTLTVIYSEDHI
Sbjct: 1   MAVTTRLTWLHEKILQNHFGGKRLSLLYKGSVHGFRNGVLLDRCCNQGPTLTVIYSEDHI 60

Query: 61  IGAYAEESYQEGKYASIILFALQDTKISEWKLGLCTPETLFCCDVTKYNSPTNFQIDGRN 120
           IGAYAEESYQEGKYASIILFALQDTKISEWKLGLCTPETLFCCDVTKYNSPTNFQIDGRN
Sbjct: 61  IGAYAEESYQEGKYASIILFALQDTKISEWKLGLCTPETLFCCDVTKYNSPTNFQIDGRN 120

Query: 121 RKVIMDLKTMENLGLAQNCTISIQDYEVFRCEDSLDERKIKGVIELRKSLLSALRTYEPY 180
           RKVIMDLKTMENLGLAQNCTISIQDYEVFRCEDSLDERKIKGVIELRKSLLSALRTYEPY
Sbjct: 121 RKVIMDLKTMENLGLAQNCTISIQDYEVFRCEDSLDERKIKGVIELRKSLLSALRTYEPY 180

Query: 181 GSLVQQIRILLLGPIGAGKSSFFNSVRSVFQGHVTHQALVGTNTTGISEKYRTYSIRDGK 240
           GSLVQQIRILLLGPIGAGKSSFFNSVRSVFQGHVTHQALVGTNTTGISEKYRTYSIRDGK
Sbjct: 181 GSLVQQIRILLLGPIGAGKSSFFNSVRSVFQGHVTHQALVGTNTTGISEKYRTYSIRDGK 240

Query: 241 DGKYLPFILCDSLGLSEKEGGLCRDDIFYILNGNIRDRYQFNPMESIKLNHHDYIDSPSL 300
           DGKYLPFILCDSLGLSEKEGGLCRDDIFYILNGNIRDRYQFNPMESIKLNHHDYIDSPSL
Sbjct: 241 DGKYLPFILCDSLGLSEKEGGLCRDDIFYILNGNIRDRYQFNPMESIKLNHHDYIDSPSL 300

Query: 301 KDRIHCVAFVFDASSIQYFSSQMIVKIKRIRRELVNAGVVHVALLTHVDSMDLITKGDLI 360
           KDRIHCVAFVFDASSIQYFSSQMIVKIKRIRRELVNAGVVHVALLTHVDSMDLITKGDLI
Sbjct: 301 KDRIHCVAFVFDASSIQYFSSQMIVKIKRIRRELVNAGVVHVALLTHVDSMDLITKGDLI 360

Query: 361 EIERCEPVRSKLEEVQRKLGFALSDISVVSNYSSEWELDPVKDVLILSALRRMLWAADDF 420
           EIERCEPVRSKLEEVQRKLGFALSDISVVSNYSSEWELDPVKDVLILSALRRMLWAADDF
Sbjct: 361 EIERCEPVRSKLEEVQRKLGFALSDISVVSNYSSEWELDPVKDVLILSALRRMLWAADDF 420

Query: 421 LEDLPFEQIGNLREEIINCAQGKK 444
           LEDLPFEQIGNLREEIINCAQGKK
Sbjct: 421 LEDLPFEQIGNLREEIINCAQGKK 444


>gi|166706909 interferon-induced protein 44-like [Homo sapiens]
          Length = 452

 Score =  352 bits (904), Expect = 3e-97
 Identities = 205/455 (45%), Positives = 287/455 (63%), Gaps = 20/455 (4%)

Query: 1   MAVTTRLTWLHEKILQNHFGGKRLSLLYKGSVHGFRNGVLLDRCCNQGPTLTVIYSEDHI 60
           M VTTRLTW  E  L+   G   LSLLYK SVHG     +++RC  QG T+T+ Y + ++
Sbjct: 1   MEVTTRLTWNDENHLRKLLGNVSLSLLYKSSVHGGSIEDMVERCSRQGCTITMAYIDYNM 60

Query: 61  IGAYAEESYQEGKYASI-----ILFALQ---DTKISEWKLGLCTPETL---FCCDVTKYN 109
           I A+   +Y     +S      + F+LQ   DT   E  L    P+ +     C ++K  
Sbjct: 61  IVAFMLGNYINLHESSTEPNDSLWFSLQKKNDTTEIETLLLNTAPKIIDEQLVCRLSK-- 118

Query: 110 SPTNFQIDGRNRKVIMDLKTMENLGLAQNCTISIQDYEVFRCE---DSLDE-RKIKGVIE 165
             T+  I  R+ K+ +D     NL L         + EVFR E   D+LD+ ++I    E
Sbjct: 119 --TDIFIICRDNKIYLDKMITRNLKLRFYGHRQYLECEVFRVEGIKDNLDDIKRIIKARE 176

Query: 166 LRKSLLSALRTYEPYGSLVQQIRILLLGPIGAGKSSFFNSVRSVFQGHVTHQALVGTNTT 225
            R  LL+ +R Y PY  LV +IRILL+GP+G+GKSSFFNSV+S+F GHVT QA+VG++ T
Sbjct: 177 HRNRLLADIRDYRPYADLVSEIRILLVGPVGSGKSSFFNSVKSIFHGHVTGQAVVGSDIT 236

Query: 226 GISEKYRTYSIRDGKDGKYLPFILCDSLGLSEKEG-GLCRDDIFYILNGNIRDRYQFNPM 284
            I+E+YR YS++DGK+GK LPF+LCD++GL   EG GLC DDI +IL G + DRYQFN  
Sbjct: 237 SITERYRIYSVKDGKNGKSLPFMLCDTMGLDGAEGAGLCMDDIPHILKGCMPDRYQFNSR 296

Query: 285 ESIKLNHHDYIDSPSLKDRIHCVAFVFDASSIQYFSSQMIVKIKRIRRELVNAGVVHVAL 344
           + I   H  +I SPSLKDRIHCVA+V D +SI    S+M+ K+K++ +E++N G+ +VAL
Sbjct: 297 KPITPEHSTFITSPSLKDRIHCVAYVLDINSIDNLYSKMLAKVKQVHKEVLNCGIAYVAL 356

Query: 345 LTHVDSMDLITKGDLIEIERCEPVRSKLEEVQRKLGFALSDISVVSNYSSEWELDPVKDV 404
           LT VD    + + + + + R    +S++  V + LG  +S+I +V NY+S+ ELDP+KD+
Sbjct: 357 LTKVDDCSEVLQDNFLNMSRSMTSQSRVMNVHKMLGIPISNILMVGNYASDLELDPMKDI 416

Query: 405 LILSALRRMLWAADDFLEDLPFEQIGNLREEIINC 439
           LILSALR+ML AADDFLEDLP E+ G +   +  C
Sbjct: 417 LILSALRQMLRAADDFLEDLPLEETGAIERALQPC 451


>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
          Length = 4314

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 12/34 (35%), Positives = 23/34 (67%)

Query: 175  RTYEPYGSLVQQIRILLLGPIGAGKSSFFNSVRS 208
            +  E Y  L Q++ ++++GP GAGKS+ +  +R+
Sbjct: 1961 KALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRA 1994


>gi|56119214 GTPase, IMAP family member 6 [Homo sapiens]
          Length = 292

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 8/82 (9%)

Query: 144 QDYEVFRCEDSLDERKIKGVIELRKSLLSALRTYEPYGSLVQQIRILLLGPIGAGKSSFF 203
           ++YE    E+  +E     V+EL   L       E      +++R++L+G  G+GKS+  
Sbjct: 4   EEYEQIPQENPPEELSQDPVLELSGGLR------EKEQKTPRRLRLILMGKTGSGKSATG 57

Query: 204 NSV--RSVFQGHVTHQALVGTN 223
           NS+  R VF+  ++ + +  T+
Sbjct: 58  NSILGRDVFESKLSTRPVTKTS 79


>gi|8922873 GTPase, IMAP family member 4 [Homo sapiens]
          Length = 329

 Score = 29.3 bits (64), Expect = 7.5
 Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 14/76 (18%)

Query: 186 QIRILLLGPIGAGKSSFFNSV--RSVFQGHVTHQALVGTNTTGISEKYRTYSIRDGKDGK 243
           Q+RI+L+G  GAGKS+  NS+  R VF          GT    I++K    S       K
Sbjct: 30  QLRIVLVGKTGAGKSATGNSILGRKVFHS--------GTAAKSITKKCEKRS----SSWK 77

Query: 244 YLPFILCDSLGLSEKE 259
               ++ D+ G+ + E
Sbjct: 78  ETELVVVDTPGIFDTE 93


>gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo
           sapiens]
          Length = 646

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 13/99 (13%)

Query: 168 KSLLSALRTYEPYGSLVQQIRILLLGPIGAGKSSFFNSVRSVFQGHVTHQALVGTNTTGI 227
           K+LL  L      G   ++  I ++GP GAGKS+F N +    +  +  Q LV      +
Sbjct: 82  KTLLKCLS-----GKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPREL 136

Query: 228 SEKYRTYSIRDGKDGKYLP-------FILCDSLGLSEKE 259
              +R  S    +D   LP        ++  +L LSEK+
Sbjct: 137 -RTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQ 174


>gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo
           sapiens]
          Length = 646

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 13/99 (13%)

Query: 168 KSLLSALRTYEPYGSLVQQIRILLLGPIGAGKSSFFNSVRSVFQGHVTHQALVGTNTTGI 227
           K+LL  L      G   ++  I ++GP GAGKS+F N +    +  +  Q LV      +
Sbjct: 82  KTLLKCLS-----GKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPREL 136

Query: 228 SEKYRTYSIRDGKDGKYLP-------FILCDSLGLSEKE 259
              +R  S    +D   LP        ++  +L LSEK+
Sbjct: 137 -RTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQ 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,934,358
Number of Sequences: 37866
Number of extensions: 670023
Number of successful extensions: 1497
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1492
Number of HSP's gapped (non-prelim): 7
length of query: 444
length of database: 18,247,518
effective HSP length: 105
effective length of query: 339
effective length of database: 14,271,588
effective search space: 4838068332
effective search space used: 4838068332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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