Guide to the Human Genome
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Search of human proteins with 156627575

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156627575 UDP-N-acetylglucosamine pyrophosphorylase 1 [Homo
sapiens]
         (505 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156627575 UDP-N-acetylglucosamine pyrophosphorylase 1 [Homo s...  1022   0.0  
gi|187936958 UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 ...   583   e-166
gi|48255966 UDP-glucose pyrophosphorylase 2 isoform a [Homo sapi...    57   4e-08
gi|48255968 UDP-glucose pyrophosphorylase 2 isoform b [Homo sapi...    55   1e-07
gi|50845382 ADAM metallopeptidase domain 20 preproprotein [Homo ...    31   3.0  
gi|126723390 ankyrin repeat domain 24 [Homo sapiens]                   30   6.7  
gi|33667038 syntaxin 11 [Homo sapiens]                                 29   8.8  

>gi|156627575 UDP-N-acetylglucosamine pyrophosphorylase 1 [Homo
           sapiens]
          Length = 505

 Score = 1022 bits (2642), Expect = 0.0
 Identities = 505/505 (100%), Positives = 505/505 (100%)

Query: 1   MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS 60
           MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS
Sbjct: 1   MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS 60

Query: 61  HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY 120
           HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY
Sbjct: 61  HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY 120

Query: 121 PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK 180
           PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK
Sbjct: 121 PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK 180

Query: 181 HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME 240
           HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME
Sbjct: 181 HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME 240

Query: 241 QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ 300
           QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ
Sbjct: 241 QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ 300

Query: 301 VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY 360
           VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY
Sbjct: 301 VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY 360

Query: 361 VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT 420
           VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT
Sbjct: 361 VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT 420

Query: 421 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRLKDANDVPIQCEISPLISYAGEGLESY 480
           ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRLKDANDVPIQCEISPLISYAGEGLESY
Sbjct: 421 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRLKDANDVPIQCEISPLISYAGEGLESY 480

Query: 481 VADKEFHAPLIIDENGVHELVKNGI 505
           VADKEFHAPLIIDENGVHELVKNGI
Sbjct: 481 VADKEFHAPLIIDENGVHELVKNGI 505


>gi|187936958 UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
           [Homo sapiens]
          Length = 507

 Score =  583 bits (1503), Expect = e-166
 Identities = 293/497 (58%), Positives = 369/497 (74%), Gaps = 3/497 (0%)

Query: 5   DLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQS-SHQK 63
           D++  L +AGQEHLLRFW EL    +  L AEL  +  E L    ++A E   +      
Sbjct: 6   DVRARLQRAGQEHLLRFWAELAPEPRAALLAELALLEPEALREHCRRAAEACARPHGPPP 65

Query: 64  NVDARMEPVPREVLGSATR-DQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPK 122
           ++ AR+ P+P E +G A+R D +  + WE EG  QIS NKVAVLLLAGGQGTRLGV YPK
Sbjct: 66  DLAARLRPLPPERVGRASRSDPETRRRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPK 125

Query: 123 GMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHK 182
           GMY VGLPSRKTL+Q+QAERI +++Q+A + +G +C +PWY+MTS  T+  T EFF +H 
Sbjct: 126 GMYRVGLPSRKTLYQLQAERIRRVEQLAGERHGTRCTVPWYVMTSEFTLGPTAEFFREHN 185

Query: 183 YFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQR 242
           +F L   NV+ F+Q +LPA++FDGK+ILE K+KV+MAPDGNGGLY AL    I+EDME+R
Sbjct: 186 FFHLDPANVVMFEQRLLPAVTFDGKVILERKDKVAMAPDGNGGLYCALEDHKILEDMERR 245

Query: 243 GIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVV 302
           G+  +HVYCVDNILV++ADP FIGFC+ +GADCGAKVVEK  P EPVGVVC+VDGV QVV
Sbjct: 246 GVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVV 305

Query: 303 EYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPYVD 362
           EYSEIS  TAQ R+SDG LL+NAGNI NHFFT  FL+ V   +EP L+ HVA KK+PYVD
Sbjct: 306 EYSEISPETAQLRASDGSLLYNAGNICNHFFTRGFLKAVTREFEPLLKPHVAVKKVPYVD 365

Query: 363 TQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTTAR 422
            +G L+KP KPNGIKMEKFVFD+F+FAK F   EVLRE+EFSPLKNA+  + +D+P TAR
Sbjct: 366 EEGNLVKPLKPNGIKMEKFVFDVFRFAKNFAALEVLREEEFSPLKNAEPAD-RDSPRTAR 424

Query: 423 HALMSLHHCWVLNAGGHFIDENGSRLPAIPRLKDANDVPIQCEISPLISYAGEGLESYVA 482
            AL++ H+ W L AG  F+D +G+ LP +P L    D P  CEISPL+SY+GEGLE Y+ 
Sbjct: 425 QALLTQHYRWALRAGARFLDAHGAWLPELPSLPPNGDPPAICEISPLVSYSGEGLEVYLQ 484

Query: 483 DKEFHAPLIIDENGVHE 499
            +EF +PLI+DE+   E
Sbjct: 485 GREFQSPLILDEDQARE 501


>gi|48255966 UDP-glucose pyrophosphorylase 2 isoform a [Homo
           sapiens]
          Length = 508

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 78/345 (22%), Positives = 142/345 (41%), Gaps = 36/345 (10%)

Query: 3   INDLKLTLSKAGQEHLLR-FWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSH 61
           + DL   +S+ G          ELE + + EL   L   +  E     +K ++GF +  H
Sbjct: 5   VQDLSKAMSQDGASQFQEVIRQELELSVKKELEKILTTASSHEFEHT-KKDLDGFRKLFH 63

Query: 62  QKNVDARMEPVPREVLGSATRD-QDQLQAWE---SEGL---FQISQNKVAVLLLAGGQGT 114
           +       E  P    G   R  +D +Q +E   + GL        NK+ V+ L GG GT
Sbjct: 64  R----FLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGT 119

Query: 115 RLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMEST 174
            +G   PK +  +G+ +  T   +  ++I  L     K Y     +P  +M S  T E T
Sbjct: 120 SMGCKGPKSL--IGVRNENTFLDLTVQQIEHL----NKTYNTD--VPLVLMNSFNTDEDT 171

Query: 175 KEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEE------KNKVSMAPDGNGGLYR 228
           K+   K+ +  +K   +  F Q   P ++ +  + + +      +N  +  P G+G +Y 
Sbjct: 172 KKILQKYNHCRVK---IYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYA 228

Query: 229 ALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQ----KGADCGAKVVEKTN 284
           +     +++     G   I V  +DN+   V D   +   +     K  +   +V  KT 
Sbjct: 229 SFYNSGLLDTFIGEGKEYIFVSNIDNLGATV-DLYILNHLMNPPNGKRCEFVMEVTNKTR 287

Query: 285 PTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRL-LFNAGNI 328
                G + + +G  ++VE +++  A   +  S  +  +FN  N+
Sbjct: 288 ADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNL 332


>gi|48255968 UDP-glucose pyrophosphorylase 2 isoform b [Homo
           sapiens]
          Length = 497

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 74/323 (22%), Positives = 135/323 (41%), Gaps = 35/323 (10%)

Query: 24  ELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNVDARMEPVPREVLGSATRD 83
           ELE + + EL   L   +  E     +K ++GF +  H+       E  P    G   R 
Sbjct: 16  ELELSVKKELEKILTTASSHEFEHT-KKDLDGFRKLFHR----FLQEKGPSVDWGKIQRP 70

Query: 84  -QDQLQAWE---SEGL---FQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLF 136
            +D +Q +E   + GL        NK+ V+ L GG GT +G   PK +  +G+ +  T  
Sbjct: 71  PEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSL--IGVRNENTFL 128

Query: 137 QIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQ 196
            +  ++I  L     K Y     +P  +M S  T E TK+   K+ +  +K   +  F Q
Sbjct: 129 DLTVQQIEHL----NKTYNTD--VPLVLMNSFNTDEDTKKILQKYNHCRVK---IYTFNQ 179

Query: 197 GMLPAMSFDGKIILEE------KNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVY 250
              P ++ +  + + +      +N  +  P G+G +Y +     +++     G   I V 
Sbjct: 180 SRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVS 239

Query: 251 CVDNILVKVADPRFIGFCIQ----KGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSE 306
            +DN+   V D   +   +     K  +   +V  KT      G + + +G  ++VE ++
Sbjct: 240 NIDNLGATV-DLYILNHLMNPPNGKRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQ 298

Query: 307 ISLATAQKRSSDGRL-LFNAGNI 328
           +  A   +  S  +  +FN  N+
Sbjct: 299 VPKAHVDEFKSVSKFKIFNTNNL 321


>gi|50845382 ADAM metallopeptidase domain 20 preproprotein [Homo
           sapiens]
          Length = 776

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 17/52 (32%), Positives = 24/52 (46%)

Query: 73  PREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGM 124
           P    G      +    W++  L    Q+ VA L +   QG +LGVAY KG+
Sbjct: 315 PLPTSGDLDNVLEDFSIWKNYNLNNRLQHDVAHLFIKDTQGMKLGVAYVKGI 366


>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
          Length = 1146

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 11/97 (11%)

Query: 6   LKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNV 65
           L   LS + QEHL         A   E  A L   N E +     + +E F +   Q  V
Sbjct: 429 LSRQLSPSAQEHL---------ASLQEQVAVLTRQNQELMEKV--QILENFEKDETQMEV 477

Query: 66  DARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNK 102
           +A  E +P  +  S   + DQL+   +E L  + Q +
Sbjct: 478 EALAEVIPLALYDSLRAEFDQLRRQHAEALQALRQQE 514


>gi|33667038 syntaxin 11 [Homo sapiens]
          Length = 287

 Score = 29.3 bits (64), Expect = 8.8
 Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 11/84 (13%)

Query: 19  LRFWNELEEAQQVE-----LYAELQAMNFEELNFFFQKAIEGFNQSSHQK------NVDA 67
           LR   EL EA + +       A +    +  L   FQ+A+  +NQ+  ++       +  
Sbjct: 104 LRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQR 163

Query: 68  RMEPVPREVLGSATRDQDQLQAWE 91
           ++E + +EV G    D  +   W+
Sbjct: 164 QLEIMGKEVSGDQIEDMFEQGKWD 187


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,587,131
Number of Sequences: 37866
Number of extensions: 822133
Number of successful extensions: 1642
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1632
Number of HSP's gapped (non-prelim): 7
length of query: 505
length of database: 18,247,518
effective HSP length: 107
effective length of query: 398
effective length of database: 14,195,856
effective search space: 5649950688
effective search space used: 5649950688
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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