Search of human proteins with 156616279

Search of human proteins with 156616279

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156616279 inosine monophosphate dehydrogenase 1 isoform c
[Homo sapiens]
         (589 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156616279 inosine monophosphate dehydrogenase 1 isoform c [Ho...  1157   0.0  
gi|34328930 inosine monophosphate dehydrogenase 1 isoform a [Hom...  1138   0.0  
gi|34328928 inosine monophosphate dehydrogenase 1 isoform b [Hom...  1095   0.0  
gi|217035152 inosine monophosphate dehydrogenase 1 isoform d [Ho...  1055   0.0  
gi|217035146 inosine monophosphate dehydrogenase 1 isoform e [Ho...  1008   0.0  
gi|217035148 inosine monophosphate dehydrogenase 1 isoform f [Ho...   993   0.0  
gi|217035150 inosine monophosphate dehydrogenase 1 isoform g [Ho...   941   0.0  
gi|66933016 inosine monophosphate dehydrogenase 2 [Homo sapiens]      872   0.0  
gi|50541948 guanosine monophosphate reductase 2 isoform 2 [Homo ...   122   7e-28
gi|50541954 guanosine monophosphate reductase 2 isoform 2 [Homo ...   122   7e-28
gi|50541952 guanosine monophosphate reductase 2 isoform 2 [Homo ...   122   7e-28
gi|50541956 guanosine monophosphate reductase 2 isoform 1 [Homo ...   122   7e-28
gi|156104880 guanosine monophosphate reductase [Homo sapiens]         120   3e-27
gi|53729339 mitochondrial translational initiation factor 2 prec...    34   0.33 
gi|53729337 mitochondrial translational initiation factor 2 prec...    34   0.33 
gi|54234014 hydroxyacid oxidase 2 [Homo sapiens]                       33   0.73 
gi|7705393 hydroxyacid oxidase 2 [Homo sapiens]                        33   0.73 
gi|11068137 hydroxyacid oxidase 1 [Homo sapiens]                       31   2.8  

>gi|156616279 inosine monophosphate dehydrogenase 1 isoform c [Homo
           sapiens]
          Length = 589

 Score = 1157 bits (2992), Expect = 0.0
 Identities = 589/589 (100%), Positives = 589/589 (100%)

Query: 1   MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPESCFLLELSSVVL 60
           MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPESCFLLELSSVVL
Sbjct: 1   MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPESCFLLELSSVVL 60

Query: 61  LAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFI 120
           LAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFI
Sbjct: 61  LAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFI 120

Query: 121 ADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVR 180
           ADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVR
Sbjct: 121 ADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVR 180

Query: 181 KVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDF 240
           KVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDF
Sbjct: 181 KVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDF 240

Query: 241 LAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIART 300
           LAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIART
Sbjct: 241 LAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIART 300

Query: 301 DLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIA 360
           DLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIA
Sbjct: 301 DLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIA 360

Query: 361 MVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGT 420
           MVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGT
Sbjct: 361 MVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGT 420

Query: 421 AVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDG 480
           AVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDG
Sbjct: 421 AVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDG 480

Query: 481 VRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQ 540
           VRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQ
Sbjct: 481 VRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQ 540

Query: 541 HGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 589
           HGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
Sbjct: 541 HGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 589


>gi|34328930 inosine monophosphate dehydrogenase 1 isoform a [Homo
           sapiens]
          Length = 599

 Score = 1138 bits (2944), Expect = 0.0
 Identities = 586/599 (97%), Positives = 586/599 (97%), Gaps = 10/599 (1%)

Query: 1   MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPESCFL-------- 52
           MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPES  L        
Sbjct: 1   MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPESPRLDLATHPTT 60

Query: 53  --LELSSVVLLAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDF 110
              ELSSVVLLAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDF
Sbjct: 61  PRSELSSVVLLAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDF 120

Query: 111 LILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNC 170
           LILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNC
Sbjct: 121 LILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNC 180

Query: 171 TPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLV 230
           TPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLV
Sbjct: 181 TPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLV 240

Query: 231 GIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDC 290
           GIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDC
Sbjct: 241 GIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDC 300

Query: 291 DELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDS 350
           DELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDS
Sbjct: 301 DELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDS 360

Query: 351 SQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQE 410
           SQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQE
Sbjct: 361 SQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQE 420

Query: 411 VMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTE 470
           VMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTE
Sbjct: 421 VMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTE 480

Query: 471 APGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQK 530
           APGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQK
Sbjct: 481 APGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQK 540

Query: 531 FVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 589
           FVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
Sbjct: 541 FVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 599


>gi|34328928 inosine monophosphate dehydrogenase 1 isoform b [Homo
           sapiens]
          Length = 563

 Score = 1095 bits (2832), Expect = 0.0
 Identities = 563/589 (95%), Positives = 563/589 (95%), Gaps = 26/589 (4%)

Query: 1   MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPESCFLLELSSVVL 60
           MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPES           
Sbjct: 1   MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPES----------- 49

Query: 61  LAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFI 120
                          MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFI
Sbjct: 50  ---------------MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFI 94

Query: 121 ADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVR 180
           ADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVR
Sbjct: 95  ADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVR 154

Query: 181 KVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDF 240
           KVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDF
Sbjct: 155 KVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDF 214

Query: 241 LAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIART 300
           LAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIART
Sbjct: 215 LAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIART 274

Query: 301 DLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIA 360
           DLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIA
Sbjct: 275 DLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIA 334

Query: 361 MVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGT 420
           MVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGT
Sbjct: 335 MVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGT 394

Query: 421 AVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDG 480
           AVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDG
Sbjct: 395 AVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDG 454

Query: 481 VRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQ 540
           VRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQ
Sbjct: 455 VRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQ 514

Query: 541 HGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 589
           HGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
Sbjct: 515 HGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 563


>gi|217035152 inosine monophosphate dehydrogenase 1 isoform d [Homo
           sapiens]
          Length = 566

 Score = 1055 bits (2729), Expect = 0.0
 Identities = 553/599 (92%), Positives = 553/599 (92%), Gaps = 43/599 (7%)

Query: 1   MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPESCFL-------- 52
           MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPES  L        
Sbjct: 1   MEGPLTPPPLQGGGAAAVPEPGARQHPGHETAAQRYSARLLQAGYEPESPRLDLATHPTT 60

Query: 53  --LELSSVVLLAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDF 110
              ELSSVVLLAGVGVQMDRLRRAS                                 DF
Sbjct: 61  PRSELSSVVLLAGVGVQMDRLRRAS---------------------------------DF 87

Query: 111 LILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNC 170
           LILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNC
Sbjct: 88  LILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNC 147

Query: 171 TPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLV 230
           TPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLV
Sbjct: 148 TPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLV 207

Query: 231 GIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDC 290
           GIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDC
Sbjct: 208 GIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDC 267

Query: 291 DELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDS 350
           DELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDS
Sbjct: 268 DELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDS 327

Query: 351 SQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQE 410
           SQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQE
Sbjct: 328 SQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQE 387

Query: 411 VMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTE 470
           VMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTE
Sbjct: 388 VMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTE 447

Query: 471 APGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQK 530
           APGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQK
Sbjct: 448 APGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQK 507

Query: 531 FVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 589
           FVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
Sbjct: 508 FVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 566


>gi|217035146 inosine monophosphate dehydrogenase 1 isoform e [Homo
           sapiens]
          Length = 514

 Score = 1008 bits (2606), Expect = 0.0
 Identities = 514/514 (100%), Positives = 514/514 (100%)

Query: 76  MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT 135
           MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT
Sbjct: 1   MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT 60

Query: 136 LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVV 195
           LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVV
Sbjct: 61  LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVV 120

Query: 196 LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT 255
           LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT
Sbjct: 121 LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT 180

Query: 256 PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS 315
           PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS
Sbjct: 181 PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS 240

Query: 316 QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI 375
           QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI
Sbjct: 241 QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI 300

Query: 376 GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP 435
           GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP
Sbjct: 301 GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP 360

Query: 436 IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM 495
           IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM
Sbjct: 361 IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM 420

Query: 496 EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR 555
           EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR
Sbjct: 421 EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR 480

Query: 556 SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 589
           SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
Sbjct: 481 SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 514


>gi|217035148 inosine monophosphate dehydrogenase 1 isoform f [Homo
           sapiens]
          Length = 509

 Score =  993 bits (2567), Expect = 0.0
 Identities = 509/514 (99%), Positives = 509/514 (99%), Gaps = 5/514 (0%)

Query: 76  MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT 135
           MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT
Sbjct: 1   MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT 60

Query: 136 LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVV 195
           LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANE     KFEQGFITDPVV
Sbjct: 61  LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANE-----KFEQGFITDPVV 115

Query: 196 LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT 255
           LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT
Sbjct: 116 LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT 175

Query: 256 PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS 315
           PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS
Sbjct: 176 PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS 235

Query: 316 QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI 375
           QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI
Sbjct: 236 QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI 295

Query: 376 GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP 435
           GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP
Sbjct: 296 GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP 355

Query: 436 IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM 495
           IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM
Sbjct: 356 IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM 415

Query: 496 EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR 555
           EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR
Sbjct: 416 EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR 475

Query: 556 SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 589
           SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
Sbjct: 476 SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 509


>gi|217035150 inosine monophosphate dehydrogenase 1 isoform g [Homo
           sapiens]
          Length = 489

 Score =  941 bits (2432), Expect = 0.0
 Identities = 489/514 (95%), Positives = 489/514 (95%), Gaps = 25/514 (4%)

Query: 76  MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT 135
           MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT
Sbjct: 1   MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT 60

Query: 136 LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVV 195
           LKTPLISSPMDTVTEADMAIAMA                         KFEQGFITDPVV
Sbjct: 61  LKTPLISSPMDTVTEADMAIAMA-------------------------KFEQGFITDPVV 95

Query: 196 LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT 255
           LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT
Sbjct: 96  LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT 155

Query: 256 PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS 315
           PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS
Sbjct: 156 PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS 215

Query: 316 QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI 375
           QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI
Sbjct: 216 QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI 275

Query: 376 GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP 435
           GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP
Sbjct: 276 GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP 335

Query: 436 IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM 495
           IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM
Sbjct: 336 IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM 395

Query: 496 EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR 555
           EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR
Sbjct: 396 EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR 455

Query: 556 SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 589
           SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
Sbjct: 456 SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 489


>gi|66933016 inosine monophosphate dehydrogenase 2 [Homo sapiens]
          Length = 514

 Score =  872 bits (2254), Expect = 0.0
 Identities = 432/514 (84%), Positives = 472/514 (91%)

Query: 76  MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT 135
           MADYLISGGT YVP+DGLTAQQLF   DGLTYNDFLILPG+IDF AD+VDLTSALT+KIT
Sbjct: 1   MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT 60

Query: 136 LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVV 195
           LKTPL+SSPMDTVTEA MAIAMAL GGIGFIHHNCTPEFQANEVRKVKK+EQGFITDPVV
Sbjct: 61  LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV 120

Query: 196 LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT 255
           LSP   V DV EAK RHGF GIPIT+TG MGS+LVGI++SRDIDFL E++H   L E+MT
Sbjct: 121 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT 180

Query: 256 PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS 315
            R +LVVAPAG+TLKEANEILQRSKKGKLPIVN+ DELVAIIARTDLKKNRDYPLASKD+
Sbjct: 181 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA 240

Query: 316 QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI 375
           +KQLLCGAA+GT EDDKYRLDLL QAGVDV+VLDSSQGNS++QI M+ YIK KYP+LQVI
Sbjct: 241 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI 300

Query: 376 GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP 435
           GGNVVTAAQAKNLIDAGVD LRVGMG GSICITQEV+ACGRPQ TAVYKV+EYARRFGVP
Sbjct: 301 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP 360

Query: 436 IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM 495
           +IADGGIQ VGH+ KALALGASTVMMGSLLAATTEAPGEYFFSDG+RLKKYRGMGSLDAM
Sbjct: 361 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM 420

Query: 496 EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR 555
           +K  SSQ RYFSE DK+K+AQGVSG++QDKGSI KFVPYLIAGIQH CQDIGA+SL+ +R
Sbjct: 421 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR 480

Query: 556 SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 589
           +MMYSGELKFEKRT SAQ+EGGVH LHSYEKRL+
Sbjct: 481 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 514


>gi|50541948 guanosine monophosphate reductase 2 isoform 2 [Homo
           sapiens]
          Length = 348

 Score =  122 bits (307), Expect = 7e-28
 Identities = 76/234 (32%), Positives = 123/234 (52%), Gaps = 9/234 (3%)

Query: 323 AAVGTREDDKYRLDLLTQA--GVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVV 380
           A+ GT   D  +L+ + +A   V  I LD + G S + +  V  +++++P   ++ GNVV
Sbjct: 101 ASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVV 160

Query: 381 TAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADG 440
           T    + LI +G D ++VG+G GS+C T++    G PQ +AV + A+ A      II+DG
Sbjct: 161 TGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDG 220

Query: 441 GIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSS 500
           G    G V KA   GA  VM+G +LA  +E+ GE    DG + K + GM S  AM+K + 
Sbjct: 221 GCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAG 280

Query: 501 SQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVL 554
               Y       + ++G +  +  KG ++  +  ++ GI+  C  +GA  L  L
Sbjct: 281 GVAEY-------RASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 327


>gi|50541954 guanosine monophosphate reductase 2 isoform 2 [Homo
           sapiens]
          Length = 348

 Score =  122 bits (307), Expect = 7e-28
 Identities = 76/234 (32%), Positives = 123/234 (52%), Gaps = 9/234 (3%)

Query: 323 AAVGTREDDKYRLDLLTQA--GVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVV 380
           A+ GT   D  +L+ + +A   V  I LD + G S + +  V  +++++P   ++ GNVV
Sbjct: 101 ASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVV 160

Query: 381 TAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADG 440
           T    + LI +G D ++VG+G GS+C T++    G PQ +AV + A+ A      II+DG
Sbjct: 161 TGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDG 220

Query: 441 GIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSS 500
           G    G V KA   GA  VM+G +LA  +E+ GE    DG + K + GM S  AM+K + 
Sbjct: 221 GCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAG 280

Query: 501 SQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVL 554
               Y       + ++G +  +  KG ++  +  ++ GI+  C  +GA  L  L
Sbjct: 281 GVAEY-------RASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 327


>gi|50541952 guanosine monophosphate reductase 2 isoform 2 [Homo
           sapiens]
          Length = 348

 Score =  122 bits (307), Expect = 7e-28
 Identities = 76/234 (32%), Positives = 123/234 (52%), Gaps = 9/234 (3%)

Query: 323 AAVGTREDDKYRLDLLTQA--GVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVV 380
           A+ GT   D  +L+ + +A   V  I LD + G S + +  V  +++++P   ++ GNVV
Sbjct: 101 ASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVV 160

Query: 381 TAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADG 440
           T    + LI +G D ++VG+G GS+C T++    G PQ +AV + A+ A      II+DG
Sbjct: 161 TGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDG 220

Query: 441 GIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSS 500
           G    G V KA   GA  VM+G +LA  +E+ GE    DG + K + GM S  AM+K + 
Sbjct: 221 GCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAG 280

Query: 501 SQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVL 554
               Y       + ++G +  +  KG ++  +  ++ GI+  C  +GA  L  L
Sbjct: 281 GVAEY-------RASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 327


>gi|50541956 guanosine monophosphate reductase 2 isoform 1 [Homo
           sapiens]
          Length = 366

 Score =  122 bits (307), Expect = 7e-28
 Identities = 76/234 (32%), Positives = 123/234 (52%), Gaps = 9/234 (3%)

Query: 323 AAVGTREDDKYRLDLLTQA--GVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVV 380
           A+ GT   D  +L+ + +A   V  I LD + G S + +  V  +++++P   ++ GNVV
Sbjct: 119 ASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVV 178

Query: 381 TAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADG 440
           T    + LI +G D ++VG+G GS+C T++    G PQ +AV + A+ A      II+DG
Sbjct: 179 TGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDG 238

Query: 441 GIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSS 500
           G    G V KA   GA  VM+G +LA  +E+ GE    DG + K + GM S  AM+K + 
Sbjct: 239 GCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAG 298

Query: 501 SQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVL 554
               Y       + ++G +  +  KG ++  +  ++ GI+  C  +GA  L  L
Sbjct: 299 GVAEY-------RASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 345


>gi|156104880 guanosine monophosphate reductase [Homo sapiens]
          Length = 345

 Score =  120 bits (301), Expect = 3e-27
 Identities = 73/231 (31%), Positives = 119/231 (51%), Gaps = 9/231 (3%)

Query: 326 GTREDDKYRLDLLTQA--GVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAA 383
           G+ ++D  ++  + +A   V  I LD + G S + +  V  ++ K+P   ++ GNVVT  
Sbjct: 104 GSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGE 163

Query: 384 QAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQ 443
             + LI +G D ++VG+G GS+C T+     G PQ +AV + A+ A      II+DGG  
Sbjct: 164 MVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCT 223

Query: 444 TVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQK 503
             G V KA   GA  VM+G + +  TE  GE F  +G +LK + GM S  AM K +    
Sbjct: 224 CPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVA 283

Query: 504 RYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVL 554
            Y       + ++G +  +  KG ++  +  ++ G++  C  +GA  L  L
Sbjct: 284 EY-------RASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKEL 327


>gi|53729339 mitochondrial translational initiation factor 2
           precursor [Homo sapiens]
          Length = 727

 Score = 34.3 bits (77), Expect = 0.33
 Identities = 37/144 (25%), Positives = 63/144 (43%), Gaps = 22/144 (15%)

Query: 173 EFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSG---------IPITETG 223
           + + ++VRK K   +    DP +L+P   V  ++   + HG +          +   ETG
Sbjct: 153 KLKQDKVRKNKDAVRRPQADPALLTPRSPVVTIM-GHVDHGKTTLLDKFRKTQVAAVETG 211

Query: 224 TM----GSKLVGIVTSRDIDFLAEKDHTTLLS-----EVMTPRIELVVAPAGVTLKEANE 274
            +    G+ LV + +   I FL    H    +       +T  + LVVA     +K+  E
Sbjct: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271

Query: 275 ILQRSKKGKLPI---VNDCDELVA 295
            +Q +K  ++PI   VN CD+  A
Sbjct: 272 SIQHAKDAQVPIILAVNKCDKAEA 295


>gi|53729337 mitochondrial translational initiation factor 2
           precursor [Homo sapiens]
          Length = 727

 Score = 34.3 bits (77), Expect = 0.33
 Identities = 37/144 (25%), Positives = 63/144 (43%), Gaps = 22/144 (15%)

Query: 173 EFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSG---------IPITETG 223
           + + ++VRK K   +    DP +L+P   V  ++   + HG +          +   ETG
Sbjct: 153 KLKQDKVRKNKDAVRRPQADPALLTPRSPVVTIM-GHVDHGKTTLLDKFRKTQVAAVETG 211

Query: 224 TM----GSKLVGIVTSRDIDFLAEKDHTTLLS-----EVMTPRIELVVAPAGVTLKEANE 274
            +    G+ LV + +   I FL    H    +       +T  + LVVA     +K+  E
Sbjct: 212 GITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVE 271

Query: 275 ILQRSKKGKLPI---VNDCDELVA 295
            +Q +K  ++PI   VN CD+  A
Sbjct: 272 SIQHAKDAQVPIILAVNKCDKAEA 295


>gi|54234014 hydroxyacid oxidase 2 [Homo sapiens]
          Length = 351

 Score = 33.1 bits (74), Expect = 0.73
 Identities = 15/42 (35%), Positives = 24/42 (57%)

Query: 434 VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEY 475
           + +  DGG++T   V+KALALGA  + +G  +       GE+
Sbjct: 272 IEVYLDGGVRTGNDVLKALALGAKCIFLGRPILWGLACKGEH 313


>gi|7705393 hydroxyacid oxidase 2 [Homo sapiens]
          Length = 351

 Score = 33.1 bits (74), Expect = 0.73
 Identities = 15/42 (35%), Positives = 24/42 (57%)

Query: 434 VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEY 475
           + +  DGG++T   V+KALALGA  + +G  +       GE+
Sbjct: 272 IEVYLDGGVRTGNDVLKALALGAKCIFLGRPILWGLACKGEH 313


>gi|11068137 hydroxyacid oxidase 1 [Homo sapiens]
          Length = 370

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 18/52 (34%), Positives = 26/52 (50%)

Query: 434 VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKK 485
           V +  DGG++    V+KALALGA  V +G  +       GE    D + + K
Sbjct: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILK 337


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,709,890
Number of Sequences: 37866
Number of extensions: 880655
Number of successful extensions: 2573
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2545
Number of HSP's gapped (non-prelim): 20
length of query: 589
length of database: 18,247,518
effective HSP length: 108
effective length of query: 481
effective length of database: 14,157,990
effective search space: 6809993190
effective search space used: 6809993190
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.