Search of human proteins with 153251270

Search of human proteins with 153251270

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153251270 calcineurin-like phosphoesterase domain containing
1 isoform a [Homo sapiens]
         (314 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153251270 calcineurin-like phosphoesterase domain containing ...   652   0.0  
gi|153251272 calcineurin-like phosphoesterase domain containing ...   207   1e-53
gi|57242800 acid sphingomyelinase-like phosphodiesterase 3B isof...    31   1.2  
gi|57242798 acid sphingomyelinase-like phosphodiesterase 3B isof...    31   1.2  
gi|59889564 metallophosphoesterase 1 precursor [Homo sapiens]          30   2.8  
gi|62122917 filaggrin family member 2 [Homo sapiens]                   30   3.6  

>gi|153251270 calcineurin-like phosphoesterase domain containing 1
           isoform a [Homo sapiens]
          Length = 314

 Score =  652 bits (1681), Expect = 0.0
 Identities = 314/314 (100%), Positives = 314/314 (100%)

Query: 1   MSAAEAGGVFHRARGRTLAAFPAEKESEWKGPFYFILGADPQFGLIKAWSTGDCDNGGDE 60
           MSAAEAGGVFHRARGRTLAAFPAEKESEWKGPFYFILGADPQFGLIKAWSTGDCDNGGDE
Sbjct: 1   MSAAEAGGVFHRARGRTLAAFPAEKESEWKGPFYFILGADPQFGLIKAWSTGDCDNGGDE 60

Query: 61  WEQEIRLTEQAVQAINKLNPKPKFFVLCGDLIHAMPGKPWRTEQTEDLKRVLRAVDRAIP 120
           WEQEIRLTEQAVQAINKLNPKPKFFVLCGDLIHAMPGKPWRTEQTEDLKRVLRAVDRAIP
Sbjct: 61  WEQEIRLTEQAVQAINKLNPKPKFFVLCGDLIHAMPGKPWRTEQTEDLKRVLRAVDRAIP 120

Query: 121 LVLVSGNHDIGNTPTAETVEEFCRTWGDDYFSFWVGGVLFLVLNSQFYENPSKCPSLKQA 180
           LVLVSGNHDIGNTPTAETVEEFCRTWGDDYFSFWVGGVLFLVLNSQFYENPSKCPSLKQA
Sbjct: 121 LVLVSGNHDIGNTPTAETVEEFCRTWGDDYFSFWVGGVLFLVLNSQFYENPSKCPSLKQA 180

Query: 181 QDQWLDEQLSIARQRHCQHAIVFQHIPLFLESIDEDDDYYFNLSKSTRKKLADKFIHAGV 240
           QDQWLDEQLSIARQRHCQHAIVFQHIPLFLESIDEDDDYYFNLSKSTRKKLADKFIHAGV
Sbjct: 181 QDQWLDEQLSIARQRHCQHAIVFQHIPLFLESIDEDDDYYFNLSKSTRKKLADKFIHAGV 240

Query: 241 KVVFSGHYHRNAGGTYQNLDMVVSSAIGCQLGRDPHGLRVVVVTAEKIVHRYYSLDELSE 300
           KVVFSGHYHRNAGGTYQNLDMVVSSAIGCQLGRDPHGLRVVVVTAEKIVHRYYSLDELSE
Sbjct: 241 KVVFSGHYHRNAGGTYQNLDMVVSSAIGCQLGRDPHGLRVVVVTAEKIVHRYYSLDELSE 300

Query: 301 KGIEDDLMDLIKKK 314
           KGIEDDLMDLIKKK
Sbjct: 301 KGIEDDLMDLIKKK 314


>gi|153251272 calcineurin-like phosphoesterase domain containing 1
          isoform b [Homo sapiens]
          Length = 172

 Score =  207 bits (527), Expect = 1e-53
 Identities = 97/97 (100%), Positives = 97/97 (100%)

Query: 1  MSAAEAGGVFHRARGRTLAAFPAEKESEWKGPFYFILGADPQFGLIKAWSTGDCDNGGDE 60
          MSAAEAGGVFHRARGRTLAAFPAEKESEWKGPFYFILGADPQFGLIKAWSTGDCDNGGDE
Sbjct: 1  MSAAEAGGVFHRARGRTLAAFPAEKESEWKGPFYFILGADPQFGLIKAWSTGDCDNGGDE 60

Query: 61 WEQEIRLTEQAVQAINKLNPKPKFFVLCGDLIHAMPG 97
          WEQEIRLTEQAVQAINKLNPKPKFFVLCGDLIHAMPG
Sbjct: 61 WEQEIRLTEQAVQAINKLNPKPKFFVLCGDLIHAMPG 97



 Score =  158 bits (399), Expect = 7e-39
 Identities = 80/86 (93%), Positives = 80/86 (93%), Gaps = 2/86 (2%)

Query: 231 LADKFIHA--GVKVVFSGHYHRNAGGTYQNLDMVVSSAIGCQLGRDPHGLRVVVVTAEKI 288
           L    IHA  GVKVVFSGHYHRNAGGTYQNLDMVVSSAIGCQLGRDPHGLRVVVVTAEKI
Sbjct: 87  LCGDLIHAMPGVKVVFSGHYHRNAGGTYQNLDMVVSSAIGCQLGRDPHGLRVVVVTAEKI 146

Query: 289 VHRYYSLDELSEKGIEDDLMDLIKKK 314
           VHRYYSLDELSEKGIEDDLMDLIKKK
Sbjct: 147 VHRYYSLDELSEKGIEDDLMDLIKKK 172


>gi|57242800 acid sphingomyelinase-like phosphodiesterase 3B isoform
           2 [Homo sapiens]
          Length = 373

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 43/215 (20%), Positives = 80/215 (37%), Gaps = 31/215 (14%)

Query: 67  LTEQAVQAINKLNPKPKFFVLCGDLIHAMP----GKPWRTEQTEDLKRVLRAVDRAIPLV 122
           L   ++ A+ ++ P+P F +  GD    +P    G+    E  E L +++R V     + 
Sbjct: 70  LINSSIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVERLTKLIREVFPDTKVY 129

Query: 123 LVSGNHDI--------GNTPTAETVEEFCRTW-GDDYFSFWVGGVLF------------- 160
              GNHD         G+      + E  + W  ++  + +  G  +             
Sbjct: 130 AALGNHDFHPKNQFPAGSNNIYNQIAELWKPWLSNESIALFKKGAFYCEKLPGPSGAGRI 189

Query: 161 LVLNSQFYENPSKCPSLKQ---AQDQWLDEQLSIARQRHCQHAIVFQHIPLFLESIDEDD 217
           +VLN+  Y   +   +       Q QWL++ L+ A +      IV    P F E      
Sbjct: 190 VVLNTNLYYTSNALTADMADPGQQFQWLEDVLTDASKAGDMVYIVGHVPPGFFEKTQNKA 249

Query: 218 DYYFNLSKSTRKKLADKFIHAGVKVVFSGHYHRNA 252
            +    ++   K +     H  +   F GH+H ++
Sbjct: 250 WFREGFNEKYLKVVRKH--HRVIAGQFFGHHHTDS 282


>gi|57242798 acid sphingomyelinase-like phosphodiesterase 3B isoform
           1 [Homo sapiens]
          Length = 455

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 43/215 (20%), Positives = 80/215 (37%), Gaps = 31/215 (14%)

Query: 67  LTEQAVQAINKLNPKPKFFVLCGDLIHAMP----GKPWRTEQTEDLKRVLRAVDRAIPLV 122
           L   ++ A+ ++ P+P F +  GD    +P    G+    E  E L +++R V     + 
Sbjct: 70  LINSSIYAMKEIEPEPDFILWTGDDTPHVPDEKLGEAAVLEIVERLTKLIREVFPDTKVY 129

Query: 123 LVSGNHDI--------GNTPTAETVEEFCRTW-GDDYFSFWVGGVLF------------- 160
              GNHD         G+      + E  + W  ++  + +  G  +             
Sbjct: 130 AALGNHDFHPKNQFPAGSNNIYNQIAELWKPWLSNESIALFKKGAFYCEKLPGPSGAGRI 189

Query: 161 LVLNSQFYENPSKCPSLKQ---AQDQWLDEQLSIARQRHCQHAIVFQHIPLFLESIDEDD 217
           +VLN+  Y   +   +       Q QWL++ L+ A +      IV    P F E      
Sbjct: 190 VVLNTNLYYTSNALTADMADPGQQFQWLEDVLTDASKAGDMVYIVGHVPPGFFEKTQNKA 249

Query: 218 DYYFNLSKSTRKKLADKFIHAGVKVVFSGHYHRNA 252
            +    ++   K +     H  +   F GH+H ++
Sbjct: 250 WFREGFNEKYLKVVRKH--HRVIAGQFFGHHHTDS 282


>gi|59889564 metallophosphoesterase 1 precursor [Homo sapiens]
          Length = 396

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 16/112 (14%)

Query: 60  EWEQEIRLTEQAVQAINKLNPKPKFFVLCGDLIHAMPGKPWRTEQT--EDLKRVLRAVDR 117
           EW+ E R  + A+  +     +P+   + GD+     GK W T +   +D++R  +    
Sbjct: 95  EWQME-RAFQTALWLL-----QPEVVFILGDIFDE--GK-WSTPEAWADDVERFQKMFRH 145

Query: 118 A--IPLVLVSGNHDIGNTPTAET--VEEFCRTWGDDYFSFWVGGVLFLVLNS 165
              + L +V+GNHDIG      T  VE F + +  +    W  G+ F+++NS
Sbjct: 146 PSHVQLKVVAGNHDIGFHYEMNTYKVERFEKVFSSERLFSW-KGINFVMVNS 196


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 29.6 bits (65), Expect = 3.6
 Identities = 13/49 (26%), Positives = 24/49 (48%)

Query: 225  KSTRKKLADKFIHAGVKVVFSGHYHRNAGGTYQNLDMVVSSAIGCQLGR 273
            +S+  + +D  +H+GV    +GH H  AG  +   + +V    G   G+
Sbjct: 1650 RSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQ 1698


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,543,866
Number of Sequences: 37866
Number of extensions: 558028
Number of successful extensions: 1058
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1046
Number of HSP's gapped (non-prelim): 15
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.