Search of human proteins with 110227857

Search of human proteins with 110227857

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110227857 thiamin pyrophosphokinase 1 isoform b [Homo
sapiens]
         (194 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110227857 thiamin pyrophosphokinase 1 isoform b [Homo sapiens]     410   e-115
gi|21362110 thiamin pyrophosphokinase 1 isoform a [Homo sapiens]      387   e-108
gi|31657119 carboxypeptidase 2, cytosolic [Homo sapiens]               32   0.26 
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ...    30   1.3  
gi|5454002 putative c-Myc-responsive isoform 1 [Homo sapiens]          29   2.2  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    29   2.9  
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa...    28   3.7  
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa...    28   3.7  
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa...    28   3.7  
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap...    28   3.7  
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ...    28   6.4  
gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s...    28   6.4  

>gi|110227857 thiamin pyrophosphokinase 1 isoform b [Homo sapiens]
          Length = 194

 Score =  410 bits (1053), Expect = e-115
 Identities = 194/194 (100%), Positives = 194/194 (100%)

Query: 1   MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGANRLYDITEGER 60
           MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGANRLYDITEGER
Sbjct: 1   MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGANRLYDITEGER 60

Query: 61  ESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIEEKDLKGK 120
           ESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIEEKDLKGK
Sbjct: 61  ESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIEEKDLKGK 120

Query: 121 HRLHVDTGMEGDWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGTLVSTSNTYDGSGVVTV 180
           HRLHVDTGMEGDWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGTLVSTSNTYDGSGVVTV
Sbjct: 121 HRLHVDTGMEGDWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGTLVSTSNTYDGSGVVTV 180

Query: 181 ETDHPLLWTMAIKS 194
           ETDHPLLWTMAIKS
Sbjct: 181 ETDHPLLWTMAIKS 194


>gi|21362110 thiamin pyrophosphokinase 1 isoform a [Homo sapiens]
          Length = 243

 Score =  387 bits (993), Expect = e-108
 Identities = 194/243 (79%), Positives = 194/243 (79%), Gaps = 49/243 (20%)

Query: 1   MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGANRLYDITEGER 60
           MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGANRLYDITEGER
Sbjct: 1   MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGANRLYDITEGER 60

Query: 61  ESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIEEKDLK-- 118
           ESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIEEKDLK  
Sbjct: 61  ESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIEEKDLKVD 120

Query: 119 -----------------------------------------------GKHRLHVDTGMEG 131
                                                          GKHRLHVDTGMEG
Sbjct: 121 VIVTLGGLAGRFDQIMASVNTLFQATHITPFPIIIIQEESLIYLLQPGKHRLHVDTGMEG 180

Query: 132 DWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMA 191
           DWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMA
Sbjct: 181 DWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMA 240

Query: 192 IKS 194
           IKS
Sbjct: 241 IKS 243


>gi|31657119 carboxypeptidase 2, cytosolic [Homo sapiens]
          Length = 902

 Score = 32.3 bits (72), Expect = 0.26
 Identities = 15/44 (34%), Positives = 23/44 (52%)

Query: 90  LISTPDQDHTDFTKCLKMLQKKIEEKDLKGKHRLHVDTGMEGDW 133
           L+   D D   FT+CL  L++ + ++  K  H L  D  +EG W
Sbjct: 662 LLDFCDPDQMKFTQCLAELKELLRQEIHKKFHELGQDVDLEGSW 705


>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
           sapiens]
          Length = 462

 Score = 30.0 bits (66), Expect = 1.3
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 1/57 (1%)

Query: 91  ISTPDQDHTDFTKCLKMLQKKIEEKDLKGKHRLHVDTGMEGDWCGLIPVGQPCMQVT 147
           + T    H  FTK L   + + +E  +   HR     G  GDW G+  +GQ  + V+
Sbjct: 173 VYTVVSSHEQFTKYLNFSESEEKESHV-AMHRYQAGGGDAGDWAGVNNLGQRDLPVS 228


>gi|5454002 putative c-Myc-responsive isoform 1 [Homo sapiens]
          Length = 174

 Score = 29.3 bits (64), Expect = 2.2
 Identities = 12/33 (36%), Positives = 19/33 (57%)

Query: 39  ALLRACADGGANRLYDITEGERESFLPEFINGD 71
           A++R  ADG   +++D  EGE E+ L  +   D
Sbjct: 129 AMIRGAADGSRFQVWDYEEGEVEALLDRYFEAD 161


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 28.9 bits (63), Expect = 2.9
 Identities = 17/70 (24%), Positives = 35/70 (50%), Gaps = 8/70 (11%)

Query: 57   EGERESFLPEFIN--GDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIEE 114
            + +R+  L E  N    +  I  E+ E +  K         Q++ D TK  +++Q+++ +
Sbjct: 2887 QNDRDRLLKELKNLQQQYLQINQEITELHPLKA------QLQEYQDKTKAFQIMQEELRQ 2940

Query: 115  KDLKGKHRLH 124
            ++L  +H LH
Sbjct: 2941 ENLSWQHELH 2950


>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
           sapiens]
          Length = 1276

 Score = 28.5 bits (62), Expect = 3.7
 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 5/89 (5%)

Query: 54  DITEGERESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIE 113
           DIT   R +   + I+ D  ++  E+RE       E  + P +  TD++   +  +   E
Sbjct: 702 DITRPSRPASYKKAIDEDLTALAKELRELRI----EETNRPMKKVTDYSSSSEESESSEE 757

Query: 114 EKDLKGKHRLHVDTGMEGDWCGLIPVGQP 142
           E++  G+   H  T    D   LIP G P
Sbjct: 758 EEE-DGESETHDGTVAVSDIPRLIPTGAP 785


>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
           sapiens]
          Length = 1305

 Score = 28.5 bits (62), Expect = 3.7
 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 5/89 (5%)

Query: 54  DITEGERESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIE 113
           DIT   R +   + I+ D  ++  E+RE       E  + P +  TD++   +  +   E
Sbjct: 731 DITRPSRPASYKKAIDEDLTALAKELRELRI----EETNRPMKKVTDYSSSSEESESSEE 786

Query: 114 EKDLKGKHRLHVDTGMEGDWCGLIPVGQP 142
           E++  G+   H  T    D   LIP G P
Sbjct: 787 EEE-DGESETHDGTVAVSDIPRLIPTGAP 814


>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
           sapiens]
          Length = 1331

 Score = 28.5 bits (62), Expect = 3.7
 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 5/89 (5%)

Query: 54  DITEGERESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIE 113
           DIT   R +   + I+ D  ++  E+RE       E  + P +  TD++   +  +   E
Sbjct: 757 DITRPSRPASYKKAIDEDLTALAKELRELRI----EETNRPMKKVTDYSSSSEESESSEE 812

Query: 114 EKDLKGKHRLHVDTGMEGDWCGLIPVGQP 142
           E++  G+   H  T    D   LIP G P
Sbjct: 813 EEE-DGESETHDGTVAVSDIPRLIPTGAP 840


>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
           sapiens]
          Length = 1360

 Score = 28.5 bits (62), Expect = 3.7
 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 5/89 (5%)

Query: 54  DITEGERESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFTKCLKMLQKKIE 113
           DIT   R +   + I+ D  ++  E+RE       E  + P +  TD++   +  +   E
Sbjct: 786 DITRPSRPASYKKAIDEDLTALAKELRELRI----EETNRPMKKVTDYSSSSEESESSEE 841

Query: 114 EKDLKGKHRLHVDTGMEGDWCGLIPVGQP 142
           E++  G+   H  T    D   LIP G P
Sbjct: 842 EEE-DGESETHDGTVAVSDIPRLIPTGAP 869


>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
           sapiens]
          Length = 1004

 Score = 27.7 bits (60), Expect = 6.4
 Identities = 14/49 (28%), Positives = 22/49 (44%)

Query: 54  DITEGERESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFT 102
           ++T  E+     EF + D D +  +  +Y   +G    S  D DH  FT
Sbjct: 486 EVTSDEQPRAHVEFSDSDQDGVVSDHSDYIHLEGSSFCSESDFDHFSFT 534


>gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 1100

 Score = 27.7 bits (60), Expect = 6.4
 Identities = 14/49 (28%), Positives = 22/49 (44%)

Query: 54  DITEGERESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTDFT 102
           ++T  E+     EF + D D +  +  +Y   +G    S  D DH  FT
Sbjct: 582 EVTSDEQPRAHVEFSDSDQDGVVSDHSDYIHLEGSSFCSESDFDHFSFT 630


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,868,933
Number of Sequences: 37866
Number of extensions: 347083
Number of successful extensions: 670
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 662
Number of HSP's gapped (non-prelim): 13
length of query: 194
length of database: 18,247,518
effective HSP length: 97
effective length of query: 97
effective length of database: 14,574,516
effective search space: 1413728052
effective search space used: 1413728052
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.