Search of human proteins with 149193323

Search of human proteins with 149193323

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149193323 threonine synthase-like 2 [Homo sapiens]
         (484 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149193323 threonine synthase-like 2 [Homo sapiens]                 974   0.0  
gi|153792148 threonine synthase-like 1 [Homo sapiens]                 156   5e-38
gi|251831107 NADH dehydrogenase subunit 1 [Homo sapiens]               30   6.4  
gi|5454158 valyl-tRNA synthetase [Homo sapiens]                        30   6.4  
gi|196123579 NADH dehydrogenase subunit 1 [Homo sapiens neandert...    29   8.4  
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ...    29   8.4  

>gi|149193323 threonine synthase-like 2 [Homo sapiens]
          Length = 484

 Score =  974 bits (2519), Expect = 0.0
 Identities = 484/484 (100%), Positives = 484/484 (100%)

Query: 1   MWYVSTRGVAPRVNFEGALFSGYAPDGGLFMPEELPQLDRGTLCQWSTLSYPGLVKELCA 60
           MWYVSTRGVAPRVNFEGALFSGYAPDGGLFMPEELPQLDRGTLCQWSTLSYPGLVKELCA
Sbjct: 1   MWYVSTRGVAPRVNFEGALFSGYAPDGGLFMPEELPQLDRGTLCQWSTLSYPGLVKELCA 60

Query: 61  LFIGSELLPKDELNDLIDRAFSRFRHREVVHLSRLRNGLNVLELWHGVTYAFKDLSLSCT 120
           LFIGSELLPKDELNDLIDRAFSRFRHREVVHLSRLRNGLNVLELWHGVTYAFKDLSLSCT
Sbjct: 61  LFIGSELLPKDELNDLIDRAFSRFRHREVVHLSRLRNGLNVLELWHGVTYAFKDLSLSCT 120

Query: 121 TQFLQYFLEKREKHVTVVVGTSGDTGSAAIESVQGAKNMDIIVLLPKGHCTKIQELQMTT 180
           TQFLQYFLEKREKHVTVVVGTSGDTGSAAIESVQGAKNMDIIVLLPKGHCTKIQELQMTT
Sbjct: 121 TQFLQYFLEKREKHVTVVVGTSGDTGSAAIESVQGAKNMDIIVLLPKGHCTKIQELQMTT 180

Query: 181 VLKQNVHVFGVEGNSDELDEPIKTVFADVAFVKKHNLMSLNSINWSRVLVQMAHHFFAYF 240
           VLKQNVHVFGVEGNSDELDEPIKTVFADVAFVKKHNLMSLNSINWSRVLVQMAHHFFAYF
Sbjct: 181 VLKQNVHVFGVEGNSDELDEPIKTVFADVAFVKKHNLMSLNSINWSRVLVQMAHHFFAYF 240

Query: 241 QCTPSLDTHPLPLVEVVVPTGAAGNLAAGYIAQKIGLPIRLVVAVNRNDIIHRTVQQGDF 300
           QCTPSLDTHPLPLVEVVVPTGAAGNLAAGYIAQKIGLPIRLVVAVNRNDIIHRTVQQGDF
Sbjct: 241 QCTPSLDTHPLPLVEVVVPTGAAGNLAAGYIAQKIGLPIRLVVAVNRNDIIHRTVQQGDF 300

Query: 301 SLSEAVKSTLASAMDIQVPYNMERVFWLLSGSDSQVTRALMEQFERTQSVNLPKELHSKL 360
           SLSEAVKSTLASAMDIQVPYNMERVFWLLSGSDSQVTRALMEQFERTQSVNLPKELHSKL
Sbjct: 301 SLSEAVKSTLASAMDIQVPYNMERVFWLLSGSDSQVTRALMEQFERTQSVNLPKELHSKL 360

Query: 361 SEAVTSVSVSDEAITQTMGRCWDENQYLLCPHSAVAVNYHYQQIDRQQPSTPRCCLAPAS 420
           SEAVTSVSVSDEAITQTMGRCWDENQYLLCPHSAVAVNYHYQQIDRQQPSTPRCCLAPAS
Sbjct: 361 SEAVTSVSVSDEAITQTMGRCWDENQYLLCPHSAVAVNYHYQQIDRQQPSTPRCCLAPAS 420

Query: 421 AAKFPEAVLAAGLTPETPAEIVALEHKETRCTLMRRGDNWMLMLRDTIEDLSRQWRSHAL 480
           AAKFPEAVLAAGLTPETPAEIVALEHKETRCTLMRRGDNWMLMLRDTIEDLSRQWRSHAL
Sbjct: 421 AAKFPEAVLAAGLTPETPAEIVALEHKETRCTLMRRGDNWMLMLRDTIEDLSRQWRSHAL 480

Query: 481 NTSQ 484
           NTSQ
Sbjct: 481 NTSQ 484


>gi|153792148 threonine synthase-like 1 [Homo sapiens]
          Length = 743

 Score =  156 bits (394), Expect = 5e-38
 Identities = 131/456 (28%), Positives = 210/456 (46%), Gaps = 35/456 (7%)

Query: 3   YVSTRGVAP-----RVN---FEGALFSGYAPDGGLFMP-EELPQLDRGTLCQWSTL---S 50
           ++STR V P     +V+   F  A+  G A DGGLF+P +E P+L  G   +W +L   +
Sbjct: 231 FISTRHVWPEDCEQKVSAKFFSEAVIEGLASDGGLFVPAKEFPKLSCG---EWKSLVGAT 287

Query: 51  YPGLVKELCALFIGSELLPKDELNDLIDRAFSR-FRHREVVHLSRLRNGLNVLELWHGVT 109
           Y    + L    I    +P   L ++I+ A+   F   ++  +  L     +LEL+HG T
Sbjct: 288 YVERAQILLERCIHPADIPAARLGEMIETAYGENFACSKIAPVRHLSGNQFILELFHGPT 347

Query: 110 YAFKDLSLSCTTQFLQYFLEKREKHVTVVVGTSGDTGSAAIESVQGAKNMD-----IIVL 164
            +FKDLSL        + +     ++ ++V TSGDTGSA +         D     ++  
Sbjct: 348 GSFKDLSLQLMPHIFAHCIPPSCNYM-ILVATSGDTGSAVLNGFSRLNKNDKQRIAVVAF 406

Query: 165 LPKGHCTKIQELQMTTVLKQNVHVFGVEGNSDELDEPIKTVFADVAFVKKHN------LM 218
            P+   +  Q+ Q+    ++N    GVE + D     IK +F D  F           L 
Sbjct: 407 FPENGVSDFQKAQIIGSQRENGWAVGVESDFDFCQTAIKRIFNDSDFTGFLTVEYGTILS 466

Query: 219 SLNSINWSRVLVQMAHHFFAYFQCTPSLDTHPLPLVEVVVPTGAAGNLAAGYIAQKIGLP 278
           S NSINW R+L Q+ +H  AY              V+V +PTG  GN+ A   A+ +G+P
Sbjct: 467 SANSINWGRLLPQVVYHASAYLDLVSQGFISFGSPVDVCIPTGNFGNILAAVYAKMMGIP 526

Query: 279 IR-LVVAVNRNDIIHRTVQQGDFSLSEA-VKSTLASAMDIQVPYNMERVFWLLSGSDSQV 336
           IR  + A N+N ++   ++ G + L E  +  T + ++DI    N+ER   L++  D Q+
Sbjct: 527 IRKFICASNQNHVLTDFIKTGHYDLRERKLAQTFSPSIDILKSSNLERHLHLMANKDGQL 586

Query: 337 TRALMEQFERTQSVNLPKELHSKLSEAVTSVSVSDEAITQTMGRCWDENQYLLCPHSAVA 396
              L  + E      + K L  KL +   +   S+      +   ++ + Y+L PH+AVA
Sbjct: 587 MTELFNRLESQHHFQIEKALVEKLQQDFVADWCSEGECLAAINSTYNTSGYILDPHTAVA 646

Query: 397 VNYHYQQIDRQQPST-PRCCLAPASAAKFPEAVLAA 431
                   DR Q  T P    + A  +KF  A++ A
Sbjct: 647 ----KVVADRVQDKTCPVIISSTAHYSKFAPAIMQA 678


>gi|251831107 NADH dehydrogenase subunit 1 [Homo sapiens]
          Length = 318

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 13/105 (12%)

Query: 1   MWYVSTRGVAPRVNF-----EGALFSGY------APDGGLFMPEELPQLDRGTLCQWSTL 49
           MW++ST     R  F     E  L SG+       P    FM E    +   TL     L
Sbjct: 184 MWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTTIFL 243

Query: 50  --SYPGLVKELCALFIGSELLPKDELNDLIDRAFSRFRHREVVHL 92
             +Y  L  EL   +  ++ L    L   I  A+ RFR+ +++HL
Sbjct: 244 GTTYDALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHL 288


>gi|5454158 valyl-tRNA synthetase [Homo sapiens]
          Length = 1264

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 7/98 (7%)

Query: 369  VSDEAITQTMGRCWDENQYLLCPHSAVAVNYHYQQIDRQQP-STPRCCLAPASAAKFPEA 427
            V+ E   QT+  C D    LL P         +Q++ R+ P + P  C+ P     +PE 
Sbjct: 1040 VAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRMPQAPPSLCVTP-----YPEP 1094

Query: 428  VLAAGLTPETPAEIVALEHKETRCTLMRRGDNWMLMLR 465
               +   PE  A +  L    TR     R D  +  +R
Sbjct: 1095 SECSWKDPEAEAAL-ELALSITRAVRSLRADYNLTRIR 1131


>gi|196123579 NADH dehydrogenase subunit 1 [Homo sapiens
           neanderthalensis]
          Length = 318

 Score = 29.3 bits (64), Expect = 8.4
 Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 13/105 (12%)

Query: 1   MWYVSTRGVAPRVNF-----EGALFSGY------APDGGLFMPEELPQLDRGTLCQWSTL 49
           MW++ST     R  F     E  L SG+       P    FM E    +   TL     L
Sbjct: 184 MWFISTLAETNRTPFDLAEGESELVSGFNIEYAAGPFALFFMAEYTNIIMMNTLTTTIFL 243

Query: 50  --SYPGLVKELCALFIGSELLPKDELNDLIDRAFSRFRHREVVHL 92
             +Y  L  EL   +  ++ L    L   I  A+ RFR+ +++HL
Sbjct: 244 GTTYNALSPELYTTYFVTKTLLLTSLFLWIRTAYPRFRYDQLMHL 288


>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
           sapiens]
          Length = 4621

 Score = 29.3 bits (64), Expect = 8.4
 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 20/123 (16%)

Query: 341 MEQFERTQSVNLPKELHSKLSEAVTSVSVSDEAIT--QTMGRCWDENQYLLCPHSAVAVN 398
           +E+ E+ Q  + P+E+       V   S+ + AIT   + G C D NQ    PH  + + 
Sbjct: 176 VEEAEKVQKSSAPREVQKTEESKVPEDSLEECAITCSNSHGPC-DSNQ----PHKNIKIT 230

Query: 399 YHYQQIDR-----QQPSTPRCCLA--------PASAAKFPEAVLAAGLTPETPAEIVALE 445
           +   +++      ++ S   C  A        P S+A     V++AG      AE+  LE
Sbjct: 231 FEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE 290

Query: 446 HKE 448
             E
Sbjct: 291 INE 293


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,647,490
Number of Sequences: 37866
Number of extensions: 767897
Number of successful extensions: 1693
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1684
Number of HSP's gapped (non-prelim): 8
length of query: 484
length of database: 18,247,518
effective HSP length: 106
effective length of query: 378
effective length of database: 14,233,722
effective search space: 5380346916
effective search space used: 5380346916
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.