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Search of human proteins with 145699123
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
(2073 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145699123 dedicator of cytokinesis 11 [Homo sapiens] 4165 0.0
gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens] 2437 0.0
gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens] 2388 0.0
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens] 2071 0.0
gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens] 1429 0.0
gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens] 1380 0.0
gi|157426887 dedicator of cytokinesis 6 [Homo sapiens] 822 0.0
gi|54112429 dedicator of cytokinesis 7 [Homo sapiens] 625 e-178
gi|238231392 dedicator of cytokinesis 8 [Homo sapiens] 588 e-167
gi|31415870 dedicator of cytokinesis 3 [Homo sapiens] 92 4e-18
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens] 79 4e-14
gi|117553586 dedicator of cytokinesis 5 [Homo sapiens] 71 1e-11
gi|4503355 dedicator of cytokinesis 1 [Homo sapiens] 69 4e-11
gi|31377468 dedicator of cytokinesis 2 [Homo sapiens] 59 4e-08
gi|219689123 pleckstrin homology domain containing, family A mem... 47 2e-04
gi|19923493 pleckstrin homology domain containing, family A memb... 47 2e-04
gi|154354979 myosin X [Homo sapiens] 45 7e-04
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap... 45 7e-04
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi... 45 7e-04
gi|62241015 AKT1 kinase [Homo sapiens] 44 0.002
gi|62241013 AKT1 kinase [Homo sapiens] 44 0.002
gi|62241011 AKT1 kinase [Homo sapiens] 44 0.002
gi|238859653 pleckstrin homology domain containing family A memb... 40 0.024
gi|238859651 pleckstrin homology domain containing family A memb... 40 0.024
gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sa... 40 0.031
gi|239047795 pleckstrin homology domain containing, family A mem... 39 0.053
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 39 0.053
gi|217416392 pleckstrin homology domain containing, family H (wi... 38 0.12
gi|83716021 GRB2-associated binding protein family, member 4 [Ho... 38 0.12
gi|46370073 GRB2-associated binding protein 1 isoform b [Homo sa... 37 0.20
>gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
Length = 2073
Score = 4165 bits (10801), Expect = 0.0
Identities = 2073/2073 (100%), Positives = 2073/2073 (100%)
Query: 1 MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDP 60
MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDP
Sbjct: 1 MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDP 60
Query: 61 LRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYE 120
LRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYE
Sbjct: 61 LRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYE 120
Query: 121 DFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNST 180
DFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNST
Sbjct: 121 DFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNST 180
Query: 181 ITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAF 240
ITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAF
Sbjct: 181 ITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAF 240
Query: 241 ELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKA 300
ELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKA
Sbjct: 241 ELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKA 300
Query: 301 ENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFE 360
ENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFE
Sbjct: 301 ENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFE 360
Query: 361 EKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLN 420
EKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLN
Sbjct: 361 EKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLN 420
Query: 421 PPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVAR 480
PPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVAR
Sbjct: 421 PPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVAR 480
Query: 481 IEKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQG 540
IEKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQG
Sbjct: 481 IEKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQG 540
Query: 541 SLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLSNC 600
SLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLSNC
Sbjct: 541 SLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLSNC 600
Query: 601 ITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAK 660
ITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAK
Sbjct: 601 ITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAK 660
Query: 661 ARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPI 720
ARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPI
Sbjct: 661 ARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPI 720
Query: 721 HLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSAN 780
HLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSAN
Sbjct: 721 HLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSAN 780
Query: 781 LPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQS 840
LPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQS
Sbjct: 781 LPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQS 840
Query: 841 GSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIV 900
GSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIV
Sbjct: 841 GSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIV 900
Query: 901 SKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKY 960
SKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKY
Sbjct: 901 SKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKY 960
Query: 961 SWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDES 1020
SWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDES
Sbjct: 961 SWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDES 1020
Query: 1021 RNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYI 1080
RNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYI
Sbjct: 1021 RNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYI 1080
Query: 1081 PLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISV 1140
PLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISV
Sbjct: 1081 PLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISV 1140
Query: 1141 IKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRD 1200
IKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRD
Sbjct: 1141 IKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRD 1200
Query: 1201 EFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTR 1260
EFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTR
Sbjct: 1201 EFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTR 1260
Query: 1261 QSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVC 1320
QSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVC
Sbjct: 1261 QSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVC 1320
Query: 1321 LFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLN 1380
LFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLN
Sbjct: 1321 LFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLN 1380
Query: 1381 HSSTTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIH 1440
HSSTTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIH
Sbjct: 1381 HSSTTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIH 1440
Query: 1441 LAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNE 1500
LAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNE
Sbjct: 1441 LAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNE 1500
Query: 1501 ASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANS 1560
ASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANS
Sbjct: 1501 ASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANS 1560
Query: 1561 DRPMKATAFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKT 1620
DRPMKATAFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKT
Sbjct: 1561 DRPMKATAFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKT 1620
Query: 1621 WLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMK 1680
WLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMK
Sbjct: 1621 WLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMK 1680
Query: 1681 EDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYR 1740
EDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYR
Sbjct: 1681 EDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYR 1740
Query: 1741 TLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLV 1800
TLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLV
Sbjct: 1741 TLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLV 1800
Query: 1801 KLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNI 1860
KLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNI
Sbjct: 1801 KLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNI 1860
Query: 1861 SRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATD 1920
SRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATD
Sbjct: 1861 SRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATD 1920
Query: 1921 EIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKV 1980
EIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKV
Sbjct: 1921 EIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKV 1980
Query: 1981 SELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQEDT 2040
SELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQEDT
Sbjct: 1981 SELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQEDT 2040
Query: 2041 MHSPWMSNTLHVFCAISGTSSDRGYGSPRYAEV 2073
MHSPWMSNTLHVFCAISGTSSDRGYGSPRYAEV
Sbjct: 2041 MHSPWMSNTLHVFCAISGTSSDRGYGSPRYAEV 2073
>gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
Length = 2069
Score = 2437 bits (6317), Expect = 0.0
Identities = 1237/2099 (58%), Positives = 1569/2099 (74%), Gaps = 106/2099 (5%)
Query: 2 AEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPL 61
AE RKFT+ LSKPGTAAELRQSVSE VRGSV+L K K++EPLDYENVI Q+KTQI +D L
Sbjct: 11 AETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQKKTQILNDCL 70
Query: 62 RDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYED 121
R++L+FP +D +++ RQ R + STVP AE+ AQSLFV ECIKTY++DWH+VNYKYED
Sbjct: 71 REMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWHLVNYKYED 130
Query: 122 FSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTI 181
+SG+FR LP K ++ +K+P HV+E+DE+ +KDED++SL SQKGG+ K GWL+K N+NS I
Sbjct: 131 YSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAI 190
Query: 182 TVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFE 241
+VTM+ FKRR+F+L QL DGSY LN YKDEK SKE KG I+LD+C+ VVQ K+RR AFE
Sbjct: 191 SVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFE 250
Query: 242 LKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAE 301
LKM DK S+ LAA++E EMEEW+ L KI+Q+N ++ +QEK+ ++ +DDE Q K E
Sbjct: 251 LKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNG-DSHEDDE---QSKLE 306
Query: 302 NIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEE 361
+ L+ S PEL K RE E K + R LF D + Q+LDFS EP++K FEE
Sbjct: 307 GSGSGLD-SYLPELAKSAREAEIKLK---SESRVKLFYLDPDAQKLDFSSAEPEVKSFEE 362
Query: 362 KCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNP 421
K KR LV C+DL+FN+ + +N +GP TNVEPFF+ L+LFD+K N KISADFHVDLN
Sbjct: 363 KFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNH 422
Query: 422 PSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARI 481
SVR+ML +S L + S + +H E+ ++Y +QGIFSVT PHP+IFLVARI
Sbjct: 423 FSVRQMLATTSPALMNGSGQSPSVLKGILH---EAAMQYPKQGIFSVTCPHPDIFLVARI 479
Query: 482 EKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGS 541
EKVLQG+ITHCAEPY+K+SD K AQKV + AKQ C RLGQYRMPFAWAAR +FKD G+
Sbjct: 480 EKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGN 539
Query: 542 LDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEK-TKLQIIPGQLNITVECVPVDLSNC 600
LD + RFS +Y+QDS+KLS++D+LKLL++++KPEK KL +I G L+IT++ V D N
Sbjct: 540 LDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNY 599
Query: 601 ITSSYVPLKPFEKNCQN-ITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFA 659
+ SSY+P K FE + IT EVEEFVP + K+ P+TIY NHLYVYP LKYDSQK+FA
Sbjct: 600 VNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFA 659
Query: 660 KARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELP 719
KARNIA+C+EF+DSDE D+ LKCIYG+P G VFT +A+A V HH+QNPEFYDEIKIELP
Sbjct: 660 KARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELP 719
Query: 720 IHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSA 779
LH+KHHLL TF+HVSC+ ++KG+TKK+D VET VG++W+PLLKDGR++T EQ +PVSA
Sbjct: 720 TQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSA 779
Query: 780 NLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQ 839
NLP GYL + R +IKWVDG KPLLKI +HL ST+YTQD H+H FF +CQ +
Sbjct: 780 NLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTE 839
Query: 840 SGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHI 899
SG++ + EL+KYLK LHAME VMI FLP IL QLFRVLT T E+ V +N T V++H+
Sbjct: 840 SGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEE-VAVNVTRVIIHV 898
Query: 900 VSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLK 959
V++CHEEGL+S+LRS++KY+++ E A + + +HE L +M ILK SADFL+ NKLLK
Sbjct: 899 VAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLK 958
Query: 960 YSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDE 1019
YSWFFF+++ KSMA +L+E +K+KL R QRFP +YHH + +++ ++PH+T ++ + P+
Sbjct: 959 YSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEA 1018
Query: 1020 SRNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHY 1079
S+N N+SLA F+KRC T MDRGF+F IN+YIS F+P DPK L EYKFEFL+ +CNHEHY
Sbjct: 1019 SKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHY 1078
Query: 1080 IPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAIS 1139
IPLNLPM F K ++QR QD L+YSL+DE+C++HFLVGLLLRE ALQ+ E+R AIS
Sbjct: 1079 IPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAIS 1138
Query: 1140 VIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASR 1199
V+KNLLIKH+FD RY ++ QA+IA LYLP GLL+EN+QR+ RD + P +A
Sbjct: 1139 VLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDV----SPFPVNAGM 1194
Query: 1200 DEFPCGFTSPANR--------------------GSLSTDKDTAYGSFQNGHGIKREDSRG 1239
PA G++S S N + ++ DSRG
Sbjct: 1195 TVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRG 1254
Query: 1240 SLI-PEGATGFPDQGNTGENT----RQSST-RSSVSQYNRLDQYEIRSLLMCYLYIVKMI 1293
SLI + P++ + N+ +QSST +SV + ++LDQ EI+SLLMC+LYI+K +
Sbjct: 1255 SLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSM 1314
Query: 1294 SEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTM 1353
S+D L TYWNK S EL++ + EVCL F+YMGKR IA
Sbjct: 1315 SDDALFTYWNKASTSELMDFFTISEVCLHQFQYMGKRYIA-------------------- 1354
Query: 1354 PALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFHQALLEGNTATEVSLTVLDTIS 1413
R+G+M ARLQ L SL++S T NHS ++AD+ HQ+LLE N ATEV LT LDT+S
Sbjct: 1355 -----RTGMMHARLQQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLS 1409
Query: 1414 FFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFK 1473
FT FK QLL + GHNPLMKKVFD++L FL+ QSE +LK+VF +LR+ I KFPS F++
Sbjct: 1410 LFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYE 1469
Query: 1474 GRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVS 1533
GR +MCAA CYE+LKCC SK+SS R EAS LLY LMRNNF+YT +K+F+RTHLQ+II+VS
Sbjct: 1470 GRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVS 1529
Query: 1534 QLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMKEH 1593
QLIADV GG+RFQ+SL IINN ANSDR +K T+F ++VKDLTKRIRTVLMATAQMKEH
Sbjct: 1530 QLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEH 1589
Query: 1594 EKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFL 1653
E DPEML+DLQYSLAKSYASTPELRKTWLDSMA+IHVKNGD SEAAMCYVHV ALVAE+L
Sbjct: 1590 ENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYL 1649
Query: 1654 HRKK-----------------------LFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHY 1690
RK+ +F GC+AF+ ITPNIDEE +M ED GM DVH+
Sbjct: 1650 TRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHF 1709
Query: 1691 SEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKIL 1750
+E+VL+ELLEQC DGLWKAERYE+I++I KLI+PIYEKRR+FE+L +Y TLH AY+K+
Sbjct: 1710 NEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVT 1769
Query: 1751 EVMHTKKRLLGTFFRVAFYGQS--------------FFEEEDGKEYIYKEPKLTGLSEIS 1796
EVMH+ +RLLGT+FRVAF+GQ+ FFE+EDGKEYIYKEPKLT LSEIS
Sbjct: 1770 EVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEIS 1829
Query: 1797 LRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFER 1856
RL+KLY +KFG+ENVK+IQDS KVN K+LD KYA+IQVT+V P+FD+KEL ERKTEFER
Sbjct: 1830 QRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFER 1889
Query: 1857 NHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPID 1916
+HNI RF+FE P+T +GK+QG +EEQCKRRTILT + FPYVKKRIP+ + +L PI+
Sbjct: 1890 SHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIE 1949
Query: 1917 VATDEIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYP 1976
VA DE+ K AEL++LCSS +VDMI+LQLKLQG VSVQVNAGPLAYARAFL+D+ +YP
Sbjct: 1950 VAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYP 2009
Query: 1977 PKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQI 2035
KV LK++FR+F++AC AL +NERLIKEDQ+EY E +K+N+R+M KELS+I+HEQ+
Sbjct: 2010 DNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQL 2068
>gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]
Length = 2068
Score = 2388 bits (6188), Expect = 0.0
Identities = 1214/2090 (58%), Positives = 1546/2090 (73%), Gaps = 106/2090 (5%)
Query: 11 LSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPME 70
+ P + Q EA V K K++EPLDYENVI Q+KTQI +D LR++L+FP +
Sbjct: 19 IESPLQYKDAAQGEVEAESPGPVPAKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYD 78
Query: 71 DISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLP 130
D +++ RQ R + STVP AE+ AQSLFV ECIKTY++DWH+VNYKYED+SG+FR LP
Sbjct: 79 DFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLP 138
Query: 131 CKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKR 190
K ++ +K+P HV+E+DE+ +KDED++SL SQKGG+ K GWL+K N+NS I+VTM+ FKR
Sbjct: 139 NKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKR 198
Query: 191 RYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSH 250
R+F+L QL DGSY LN YKDEK SKE KG I+LD+C+ VVQ K+RR AFELKM DK S+
Sbjct: 199 RFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSY 258
Query: 251 YLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERS 310
LAA++E EMEEW+ L KI+Q+N ++ +QEK+ ++ +DDE Q K E + L+ S
Sbjct: 259 LLAADSEVEMEEWITILNKILQLNFEAAMQEKRNG-DSHEDDE---QSKLEGSGSGLD-S 313
Query: 311 MHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVN 370
PEL K RE E K + R LF D + Q+LDFS EP++K FEEK KR LV
Sbjct: 314 YLPELAKSAREAEIKLK---SESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVK 370
Query: 371 CHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWG 430
C+DL+FN+ + +N +GP TNVEPFF+ L+LFD+K N KISADFHVDLN SVR+ML
Sbjct: 371 CNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLAT 430
Query: 431 SSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNIT 490
+S L + S + +H E+ ++Y +QGIFSVT PHP+IFLVARIEKVLQG+IT
Sbjct: 431 TSPALMNGSGQSPSVLKGILH---EAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSIT 487
Query: 491 HCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSP 550
HCAEPY+K+SD K AQKV + AKQ C RLGQYRMPFAWAAR +FKD G+LD + RFS
Sbjct: 488 HCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSA 547
Query: 551 LYKQDSSKLSSEDILKLLSEYKKPEK-TKLQIIPGQLNITVECVPVDLSNCITSSYVPLK 609
+Y+QDS+KLS++D+LKLL++++KPEK KL +I G L+IT++ V D N + SSY+P K
Sbjct: 548 IYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTK 607
Query: 610 PFEKNCQN-ITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCV 668
FE + IT EVEEFVP + K+ P+TIY NHLYVYP LKYDSQK+FAKARNIA+C+
Sbjct: 608 QFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICI 667
Query: 669 EFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHL 728
EF+DSDE D+ LKCIYG+P G VFT +A+A V HH+QNPEFYDEIKIELP LH+KHHL
Sbjct: 668 EFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHL 727
Query: 729 LFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSANLPPGYLNL 788
L TF+HVSC+ ++KG+TKK+D VET VG++W+PLLKDGR++T EQ +PVSANLP GYL
Sbjct: 728 LLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGY 787
Query: 789 NDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGE 848
+ R +IKWVDG KPLLKI +HL ST+YTQD H+H FF +CQ +SG++ + E
Sbjct: 788 QELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNE 847
Query: 849 LIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGL 908
L+KYLK LHAME VMI FLP IL QLFRVLT T E+ V +N T V++H+V++CHEEGL
Sbjct: 848 LVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEE-VAVNVTRVIIHVVAQCHEEGL 906
Query: 909 DSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEII 968
+S+LRS++KY+++ E A + + +HE L +M ILK SADFL+ NKLLKYSWFFF+++
Sbjct: 907 ESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVL 966
Query: 969 AKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLA 1028
KSMA +L+E +K+KL R QRFP +YHH + +++ ++PH+T ++ + P+ S+N N+SLA
Sbjct: 967 IKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLA 1026
Query: 1029 SFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAF 1088
F+KRC T MDRGF+F IN+YIS F+P DPK L EYKFEFL+ +CNHEHYIPLNLPM F
Sbjct: 1027 VFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLPMPF 1086
Query: 1089 AKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKH 1148
K ++QR QD L+YSL+DE+C++HFLVGLLLRE ALQ+ E+R AISV+KNLLIKH
Sbjct: 1087 GKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLKNLLIKH 1146
Query: 1149 AFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFTS 1208
+FD RY ++ QA+IA LYLP GLL+EN+QR+ RD + P +A
Sbjct: 1147 SFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDV----SPFPVNAGMTVKDESLAL 1202
Query: 1209 PANR--------------------GSLSTDKDTAYGSFQNGHGIKREDSRGSLI-PEGAT 1247
PA G++S S N + ++ DSRGSLI +
Sbjct: 1203 PAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRGSLISTDSGN 1262
Query: 1248 GFPDQGNTGENT----RQSST-RSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYW 1302
P++ + N+ +QSST +SV + ++LDQ EI+SLLMC+LYI+K +S+D L TYW
Sbjct: 1263 SLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALFTYW 1322
Query: 1303 NKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGV 1362
NK S EL++ + EVCL F+YMGKR IA R+G+
Sbjct: 1323 NKASTSELMDFFTISEVCLHQFQYMGKRYIA-------------------------RTGM 1357
Query: 1363 MQARLQHLSSLESSFTLNHSSTTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKTQ 1422
M ARLQ L SL++S T NHS ++AD+ HQ+LLE N ATEV LT LDT+S FT FK Q
Sbjct: 1358 MHARLQQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQ 1417
Query: 1423 LLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAF 1482
LL + GHNPLMKKVFD++L FL+ QSE +LK+VF +LR+ I KFPS F++GR +MCAA
Sbjct: 1418 LLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRADMCAAL 1477
Query: 1483 CYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALS 1542
CYE+LKCC SK+SS R EAS LLY LMRNNF+YT +K+F+RTHLQ+II+VSQLIADV
Sbjct: 1478 CYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGI 1537
Query: 1543 GGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLID 1602
GG+RFQ+SL IINN ANSDR +K T+F ++VKDLTKRIRTVLMATAQMKEHE DPEML+D
Sbjct: 1538 GGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVD 1597
Query: 1603 LQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKK----- 1657
LQYSLAKSYASTPELRKTWLDSMA+IHVKNGD SEAAMCYVHV ALVAE+L RK+
Sbjct: 1598 LQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWE 1657
Query: 1658 ------------------LFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELL 1699
+F GC+AF+ ITPNIDEE +M ED GM DVH++E+VL+ELL
Sbjct: 1658 PPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELL 1717
Query: 1700 EQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRL 1759
EQC DGLWKAERYE+I++I KLI+PIYEKRR+FE+L +Y TLH AY+K+ EVMH+ +RL
Sbjct: 1718 EQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRL 1777
Query: 1760 LGTFFRVAFYGQS--------------FFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGE 1805
LGT+FRVAF+GQ+ FFE+EDGKEYIYKEPKLT LSEIS RL+KLY +
Sbjct: 1778 LGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSD 1837
Query: 1806 KFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNISRFVF 1865
KFG+ENVK+IQDS KVN K+LD KYA+IQVT+V P+FD+KEL ERKTEFER+HNI RF+F
Sbjct: 1838 KFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMF 1897
Query: 1866 EAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDK 1925
E P+T +GK+QG +EEQCKRRTILT + FPYVKKRIP+ + +L PI+VA DE+ K
Sbjct: 1898 EMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKK 1957
Query: 1926 TAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKD 1985
AEL++LCSS +VDMI+LQLKLQG VSVQVNAGPLAYARAFL+D+ +YP KV LK+
Sbjct: 1958 VAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKE 2017
Query: 1986 MFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQI 2035
+FR+F++AC AL +NERLIKEDQ+EY E +K+N+R+M KELS+I+HEQ+
Sbjct: 2018 VFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQL 2067
>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
Length = 2186
Score = 2071 bits (5365), Expect = 0.0
Identities = 1087/2171 (50%), Positives = 1470/2171 (67%), Gaps = 140/2171 (6%)
Query: 5 RKFTKRLSKPGTAAELRQSVSEAVRGSVVL------EKAKVVEPLDYENVIAQRKTQIYS 58
R+FT+ L +PG AAELR S + A +V EK +++EPLDYE VI + + +
Sbjct: 7 RRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLEPLDYETVIEELEKTYRN 66
Query: 59 DPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYK 118
DPL+DLL FP +D S + + RT+ STVPEDAE +A++L VKE K YS+ WHVVNYK
Sbjct: 67 DPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQWHVVNYK 126
Query: 119 YEDFSGDFRMLPCKSLRPEKIPNHVFEID-EDCEKDEDSSSLCSQKGG-------VIKQG 170
YE +SGD R LP +PEK+P+H FEID ED +KDED++S S KGG V K G
Sbjct: 127 YEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGTGVFKSG 186
Query: 171 WLHKANVNSTI--TVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACID 228
WL+K N NST+ TVT++ FK+RYF LTQLPD SYI+N YKDEK SKE KGCI+LD+C
Sbjct: 187 WLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDSCTG 246
Query: 229 VVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVET 288
VVQ ++R++AFELKM D LAAETE +M+EW+ TL +I+QI+ + +Q ++ T T
Sbjct: 247 VVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGRRSTELT 306
Query: 289 -----AQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSE 343
+ D+ + + E +S E ++H + KY ETE K +R R NLFS D +
Sbjct: 307 DLGLDSLDNSVTCECTPEETDSS-ENNLHADFAKYLTETEDTVKTTRNMERLNLFSLDPD 365
Query: 344 VQRLDFSG---IEPD--IKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFI 398
+ L +EP+ IKPFEEK KR ++ C L N+ G + +N P TN+EPFF+
Sbjct: 366 IDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNIEPFFV 425
Query: 399 NLALFDVKNNCKISADFHVDLNPPSVREMLWGSSTQLAS---DGSPKGSSPESYIHGIAE 455
++AL+D++++ KISADFHVDLN +VR+ML G+S L + D S E +I G+ E
Sbjct: 426 SVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHIKGLPE 485
Query: 456 SQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQ 515
L++ +Q +FSV+NPH EI LVA+IEKVL GNI AEPYIKN D K AQK+ ++ +Q
Sbjct: 486 EWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKILKSNRQ 545
Query: 516 VCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPE 575
CS+LG+YRMPFAWA R +FKD QG++D D RFSPL++Q+SSK+S+ED++KL+S+Y++ +
Sbjct: 546 FCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVSDYRRAD 605
Query: 576 K-TKLQIIPGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNI-TVEVEEFVPEMTKYC 633
+ +K+Q IPG L+I V+ VP++ NC+TSS++P+KPF Q TVEVEEFV + TKYC
Sbjct: 606 RISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVYDSTKYC 665
Query: 634 YPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVF 693
P+ +YKN +Y+YP LKYDSQK F KARNI VC+EF++SDE A LKCIYGKP G +F
Sbjct: 666 RPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKPGGPLF 725
Query: 694 TTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVET 753
T+ AY V HH+QNP+F DE+KIELP LH+KHH+LF+FYHV+C+IN K KK++ +ET
Sbjct: 726 TSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALET 785
Query: 754 PVGFAWVPLLKDGRIITFEQQLPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKI 813
VG+AW+PL+K +I + E +P++ +LPP YL+ D+ S + DIKWVDG KPL K+
Sbjct: 786 SVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGGKPLFKV 845
Query: 814 KSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVP-GELIKYLK-CLHAMEIQVMIQFLPVI 871
+ + ST+ TQD HV+ FF CQ + + P I+ K L+ +I ++ FLP+I
Sbjct: 846 STFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIMSFLPII 905
Query: 872 LMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQ 931
L QLF+VL ED++ T VL IV+KCHEE LD ++S+IK+ F K A + +
Sbjct: 906 LNQLFKVLV-QNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVF---KTRACKER 961
Query: 932 LIHETLATTMIAILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFP 991
+HE LA + +LK S D ++ +LK+SWFFF II KSMA +L++ NKI+LPR QRFP
Sbjct: 962 TVHEELAKNVTGLLK-SNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPRPQRFP 1020
Query: 992 ETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFIFNLINDYI 1051
E+Y + L +L++ + HV +Y + +E+R N+S+A FLKRC T MDRG++F ++N+YI
Sbjct: 1021 ESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKMVNNYI 1080
Query: 1052 SGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFA--------KPKLQRVQDSNL-E 1102
S FS D K L +YKF+FLQ +C HEH+IPL LP+ A Q + S++ E
Sbjct: 1081 SMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHASDMPE 1140
Query: 1103 YSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAK 1162
YS+++E+C+ HFL+G+LLRE ALQ++ ++R+ A++V+KNL+ KH+FD RY+ +QA+
Sbjct: 1141 YSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREPRKQAQ 1200
Query: 1163 IAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPC--GFTSP-----ANRGSL 1215
IA LY+P G+LL+N+ R+ +D N SRD+ GF S AN
Sbjct: 1201 IASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHANSVDT 1260
Query: 1216 STDKD-----TAYGSFQNGHGIKREDSRGSLIPEGATGFPDQ------GNTGENTRQSST 1264
S KD A+ S + DSR SL + ++ N + R S
Sbjct: 1261 SFSKDVLNSIAAFSSIAIS-TVNHADSRASLASLDSNPSTNEKSSEKTDNCEKIPRPLSL 1319
Query: 1265 RSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHF 1324
S ++++LDQ E RSLLMC+L+I+K IS +TL+ YW + E+ + +L+VCL +F
Sbjct: 1320 IGSTLRFDKLDQAETRSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFFSILDVCLQNF 1379
Query: 1325 RYMGKRNIAR-----------------------------VHDAWL---SKHFG-IDRKSQ 1351
RY+GKRNI R + W+ S H G +SQ
Sbjct: 1380 RYLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHSTSSHEGHKQHRSQ 1439
Query: 1352 TMPALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFHQALLEGNTATEVSLTVLDT 1411
T+P +R ++ + +L L L+++ T S + E DI H E N ATEV LT+LD
Sbjct: 1440 TLPIIRGKNALSNPKL--LQMLDNTMT----SNSNEIDIVHHVDTEANIATEVCLTILDL 1493
Query: 1412 ISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAF 1471
+S FTQ + QL D N LMK+VFD ++ F + QS +LKHVFASLR F+ KFPSAF
Sbjct: 1494 LSLFTQTHQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVCKFPSAF 1553
Query: 1472 FKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIA 1531
F+G ++C +FCYEVLKCC + ST+ EASALLY MR NFE+ K+K+ +R+HLQ+I A
Sbjct: 1554 FQGPADLCGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRSHLQLIKA 1613
Query: 1532 VSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMK 1591
VSQLIAD + GGSRFQ SL I NNFAN D+ MK + FPAEVKDLTKRIRTVLMATAQMK
Sbjct: 1614 VSQLIADAGI-GGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMK 1672
Query: 1592 EHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAE 1651
EHEKDPEML+DLQYSLA SYASTPELR+TWL+SMAKIH +NGD SEAAMCY+H+AAL+AE
Sbjct: 1673 EHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAE 1732
Query: 1652 FLHRK---------------------------------KLFPNGCSAFKKITPNIDEEGA 1678
+L RK +F G AF ITPNI EEGA
Sbjct: 1733 YLKRKGYWKVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAFLSITPNIKEEGA 1792
Query: 1679 MKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQV 1738
MKED+GM D Y+E +L+E L CV+ LWK+ERYE+I++++K I+ ++EK+R+F+KL+ +
Sbjct: 1793 MKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDL 1852
Query: 1739 YRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLR 1798
Y +H +Y K+ EV++++KRL G ++RVAFYGQ FFEEE+GKEYIYKEPKLTGLSEIS R
Sbjct: 1853 YYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQR 1912
Query: 1799 LVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNH 1858
L+KLY +KFG +NVKIIQDS+KVN K+LDPKYA+IQVTYV P+F++KE+ +RKT+FE +H
Sbjct: 1913 LLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHH 1972
Query: 1859 NISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVA 1918
NI+RFVFE P+TLSGKK G + EQCKRRTILTTS+ FPYVKKRI + + L PI+VA
Sbjct: 1973 NINRFVFETPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVA 2032
Query: 1919 TDEIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPK 1978
DE+ K +EL +LC+ +VDMI+LQLKLQG VSV+VNAGP+AYARAFL ++ A KYP
Sbjct: 2033 IDEMSKKVSELNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDN 2092
Query: 1979 KVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQE 2038
+V LK++FR+F AC AL++NERLIKEDQ+EY E L+S+++DM+ ELS +++EQI
Sbjct: 2093 QVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQITGR 2152
Query: 2039 DTMHSPWMSNT 2049
D + + T
Sbjct: 2153 DDLSKRGVDQT 2163
>gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]
Length = 1254
Score = 1429 bits (3700), Expect = 0.0
Identities = 705/1186 (59%), Positives = 908/1186 (76%), Gaps = 14/1186 (1%)
Query: 2 AEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPL 61
AE RKFT+ LSKPGTAAELRQSVSE VRGSV+L K K++EPLDYENVI Q+KTQI +D L
Sbjct: 11 AETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQKKTQILNDCL 70
Query: 62 RDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYED 121
R++L+FP +D +++ RQ R + STVP AE+ AQSLFV ECIKTY++DWH+VNYKYED
Sbjct: 71 REMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWHLVNYKYED 130
Query: 122 FSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTI 181
+SG+FR LP K ++ +K+P HV+E+DE+ +KDED++SL SQKGG+ K GWL+K N+NS I
Sbjct: 131 YSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAI 190
Query: 182 TVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFE 241
+VTM+ FKRR+F+L QL DGSY LN YKDEK SKE KG I+LD+C+ VVQ K+RR AFE
Sbjct: 191 SVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFE 250
Query: 242 LKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAE 301
LKM DK S+ LAA++E EMEEW+ L KI+Q+N ++ +QEK+ ++ +DDE Q K E
Sbjct: 251 LKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNG-DSHEDDE---QSKLE 306
Query: 302 NIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEE 361
+ L+ S PEL K RE E K + R LF D + Q+LDFS EP++K FEE
Sbjct: 307 GSGSGLD-SYLPELAKSAREAEIKLK---SESRVKLFYLDPDAQKLDFSSAEPEVKSFEE 362
Query: 362 KCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNP 421
K KR LV C+DL+FN+ + +N +GP TNVEPFF+ L+LFD+K N KISADFHVDLN
Sbjct: 363 KFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNH 422
Query: 422 PSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARI 481
SVR+ML +S L + S + +H E+ ++Y +QGIFSVT PHP+IFLVARI
Sbjct: 423 FSVRQMLATTSPALMNGSGQSPSVLKGILH---EAAMQYPKQGIFSVTCPHPDIFLVARI 479
Query: 482 EKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGS 541
EKVLQG+ITHCAEPY+K+SD K AQKV + AKQ C RLGQYRMPFAWAAR +FKD G+
Sbjct: 480 EKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGN 539
Query: 542 LDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEK-TKLQIIPGQLNITVECVPVDLSNC 600
LD + RFS +Y+QDS+KLS++D+LKLL++++KPEK KL +I G L+IT++ V D N
Sbjct: 540 LDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNY 599
Query: 601 ITSSYVPLKPFEKNCQN-ITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFA 659
+ SSY+P K FE + IT EVEEFVP + K+ P+TIY NHLYVYP LKYDSQK+FA
Sbjct: 600 VNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFA 659
Query: 660 KARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELP 719
KARNIA+C+EF+DSDE D+ LKCIYG+P G VFT +A+A V HH+QNPEFYDEIKIELP
Sbjct: 660 KARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELP 719
Query: 720 IHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSA 779
LH+KHHLL TF+HVSC+ ++KG+TKK+D VET VG++W+PLLKDGR++T EQ +PVSA
Sbjct: 720 TQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSA 779
Query: 780 NLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQ 839
NLP GYL + R +IKWVDG KPLLKI +HL ST+YTQD H+H FF +CQ +
Sbjct: 780 NLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTE 839
Query: 840 SGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHI 899
SG++ + EL+KYLK LHAME VMI FLP IL QLFRVLT T E+ V +N T V++H+
Sbjct: 840 SGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEE-VAVNVTRVIIHV 898
Query: 900 VSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLK 959
V++CHEEGL+S+LRS++KY+++ E A + + +HE L +M ILK SADFL+ NKLLK
Sbjct: 899 VAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLK 958
Query: 960 YSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDE 1019
YSWFFF+++ KSMA +L+E +K+KL R QRFP +YHH + +++ ++PH+T ++ + P+
Sbjct: 959 YSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEA 1018
Query: 1020 SRNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHY 1079
S+N N+SLA F+KRC T MDRGF+F IN+YIS F+P DPK L EYKFEFL+ +CNHEHY
Sbjct: 1019 SKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHY 1078
Query: 1080 IPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAIS 1139
IPLNLPM F K ++QR QD L+YSL+DE+C++HFLVGLLLRE ALQ+ E+R AIS
Sbjct: 1079 IPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAIS 1138
Query: 1140 VIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRD 1185
V+KNLLIKH+FD RY ++ QA+IA LYLP GLL+EN+QR+ RD
Sbjct: 1139 VLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRD 1184
>gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]
Length = 1253
Score = 1380 bits (3571), Expect = 0.0
Identities = 682/1177 (57%), Positives = 885/1177 (75%), Gaps = 14/1177 (1%)
Query: 11 LSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPME 70
+ P + Q EA V K K++EPLDYENVI Q+KTQI +D LR++L+FP +
Sbjct: 19 IESPLQYKDAAQGEVEAESPGPVPAKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYD 78
Query: 71 DISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLP 130
D +++ RQ R + STVP AE+ AQSLFV ECIKTY++DWH+VNYKYED+SG+FR LP
Sbjct: 79 DFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLP 138
Query: 131 CKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKR 190
K ++ +K+P HV+E+DE+ +KDED++SL SQKGG+ K GWL+K N+NS I+VTM+ FKR
Sbjct: 139 NKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKR 198
Query: 191 RYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSH 250
R+F+L QL DGSY LN YKDEK SKE KG I+LD+C+ VVQ K+RR AFELKM DK S+
Sbjct: 199 RFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSY 258
Query: 251 YLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERS 310
LAA++E EMEEW+ L KI+Q+N ++ +QEK+ ++ +DDE Q K E + L+ S
Sbjct: 259 LLAADSEVEMEEWITILNKILQLNFEAAMQEKRNG-DSHEDDE---QSKLEGSGSGLD-S 313
Query: 311 MHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVN 370
PEL K RE E K + R LF D + Q+LDFS EP++K FEEK KR LV
Sbjct: 314 YLPELAKSAREAEIKLK---SESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVK 370
Query: 371 CHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWG 430
C+DL+FN+ + +N +GP TNVEPFF+ L+LFD+K N KISADFHVDLN SVR+ML
Sbjct: 371 CNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLAT 430
Query: 431 SSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNIT 490
+S L + S + +H E+ ++Y +QGIFSVT PHP+IFLVARIEKVLQG+IT
Sbjct: 431 TSPALMNGSGQSPSVLKGILH---EAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSIT 487
Query: 491 HCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSP 550
HCAEPY+K+SD K AQKV + AKQ C RLGQYRMPFAWAAR +FKD G+LD + RFS
Sbjct: 488 HCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSA 547
Query: 551 LYKQDSSKLSSEDILKLLSEYKKPEK-TKLQIIPGQLNITVECVPVDLSNCITSSYVPLK 609
+Y+QDS+KLS++D+LKLL++++KPEK KL +I G L+IT++ V D N + SSY+P K
Sbjct: 548 IYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTK 607
Query: 610 PFEKNCQN-ITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCV 668
FE + IT EVEEFVP + K+ P+TIY NHLYVYP LKYDSQK+FAKARNIA+C+
Sbjct: 608 QFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICI 667
Query: 669 EFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHL 728
EF+DSDE D+ LKCIYG+P G VFT +A+A V HH+QNPEFYDEIKIELP LH+KHHL
Sbjct: 668 EFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHL 727
Query: 729 LFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSANLPPGYLNL 788
L TF+HVSC+ ++KG+TKK+D VET VG++W+PLLKDGR++T EQ +PVSANLP GYL
Sbjct: 728 LLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGY 787
Query: 789 NDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGE 848
+ R +IKWVDG KPLLKI +HL ST+YTQD H+H FF +CQ +SG++ + E
Sbjct: 788 QELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNE 847
Query: 849 LIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGL 908
L+KYLK LHAME VMI FLP IL QLFRVLT T E+ V +N T V++H+V++CHEEGL
Sbjct: 848 LVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEE-VAVNVTRVIIHVVAQCHEEGL 906
Query: 909 DSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEII 968
+S+LRS++KY+++ E A + + +HE L +M ILK SADFL+ NKLLKYSWFFF+++
Sbjct: 907 ESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVL 966
Query: 969 AKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLA 1028
KSMA +L+E +K+KL R QRFP +YHH + +++ ++PH+T ++ + P+ S+N N+SLA
Sbjct: 967 IKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLA 1026
Query: 1029 SFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAF 1088
F+KRC T MDRGF+F IN+YIS F+P DPK L EYKFEFL+ +CNHEHYIPLNLPM F
Sbjct: 1027 VFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLPMPF 1086
Query: 1089 AKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKH 1148
K ++QR QD L+YSL+DE+C++HFLVGLLLRE ALQ+ E+R AISV+KNLLIKH
Sbjct: 1087 GKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLKNLLIKH 1146
Query: 1149 AFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRD 1185
+FD RY ++ QA+IA LYLP GLL+EN+QR+ RD
Sbjct: 1147 SFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRD 1183
>gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]
Length = 2047
Score = 822 bits (2122), Expect = 0.0
Identities = 606/1942 (31%), Positives = 945/1942 (48%), Gaps = 292/1942 (15%)
Query: 300 AENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPF 359
A++++ SL PE R E L + R L+ E + ++ P+ P
Sbjct: 199 ADSLLPSLLERAAPE--DVDRRNETLRRQHRPPALLTLYPAPDEDEAVERCS-RPE--PP 253
Query: 360 EEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDL 419
E +R LV C L F I +EP F LAL+DV+ KIS +F+ DL
Sbjct: 254 REHFGQRILVKCLSLKFEI-------------EIEPIFGILALYDVREKKKISENFYFDL 300
Query: 420 NPPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVA 479
N S++ +L T A I +A S IFSVT P P+IFLV
Sbjct: 301 NSDSMKGLLRAHGTHPA-------------ISTLARS-------AIFSVTYPSPDIFLVI 340
Query: 480 RIEKVLQ-GNITHCAEPY--IKNSDPVKTAQKVHR---TAKQVCSRLGQYRMPFAWAARP 533
++EKVLQ G+I+ C EPY +K D K +K+ + A+Q C+RLG+YRMPFAW A
Sbjct: 341 KLEKVLQQGDISECCEPYMVLKEVDTAKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVH 400
Query: 534 IFK--DTQGSLDLDGR--------------------------------FSP-------LY 552
+ + G LD D F P +
Sbjct: 401 LANIVSSAGQLDRDSDSEGERRPAWTDRRRRGPQDRASSGDDACSFSGFRPATLTVTNFF 460
Query: 553 KQDSSKLSSEDILKLLSEYKKPEKT--KLQIIPGQLNITVECVPVDLSNCITSSYVPLKP 610
KQ++ +LS ED+ K L++ ++P +L+ + QL I + P + C++ + +KP
Sbjct: 461 KQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKIDISPAPENPHFCLSPELLHIKP 520
Query: 611 FEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEF 670
+ T E+ EF P Y P T Y+N LYVYP L + S++ RN+AV V++
Sbjct: 521 YPDPRGRPTKEILEF-PAREVYA-PHTSYRNLLYVYPHSLNFSSRQ--GSVRNLAVRVQY 576
Query: 671 RDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLF 730
+ E + AL I+GK + S FT A+ V +HN++PEFY+E K+ LP + + HHLLF
Sbjct: 577 M-TGEDPSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLHLPACVTENHHLLF 635
Query: 731 TFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSANLPPGYLNLND 790
TFYHVSC+ + +ETPVGF W+PLL+ GR+ T LPVS + PP ++
Sbjct: 636 TFYHVSCQ------PRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLT 689
Query: 791 AESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGS-------- 842
+ ++WVDG K + ++ S+++ QD ++ KFF +++ G+
Sbjct: 690 PDVALP---GMRWVDGHKGVFSVELTAVSSVHPQDPYLDKFFTLVHVLEEGAFPFRLKDT 746
Query: 843 ----KEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTM---- 894
V EL L L + ++ F +L +L R++ +N
Sbjct: 747 VLSEGNVEQELRASLAALRLASPEPLVAFSHHVLDKLVRLVIRPPIISGQIVNLGRGAFE 806
Query: 895 VLLHIVSKCHEE--------GLDSYLRSFIKYSFR--PEKPSAPQ--------------- 929
+ H+VS H G L +++ Y+FR +PS P
Sbjct: 807 AMAHVVSLVHRSLEAAQDARGHCPQLAAYVHYAFRLPGTEPSLPDGAPPVTVQAATLARG 866
Query: 930 --------------------------------------AQLIHETLATTMIAILKQSADF 951
++L+HE LA + +
Sbjct: 867 SGRPASLYLARSKSISSSNPDLAVAPGSVDDEVSRILASKLLHEELALQWVVSSSAVRE- 925
Query: 952 LSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTI 1011
+L+++WFFF+++ KSMA +LL ++ PR RFP + + +L+ ++ V
Sbjct: 926 ----AILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLRFPGRFLDDITALVGSVGLEVIT 981
Query: 1012 RYAEIPDESRNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPK-----DPKVLAEYK 1066
R + + + ++N SLA FL L+L+DRGF+F+L+ + + + +P L +
Sbjct: 982 RVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRAHYKQVATRLQSSPNPAALLTLR 1041
Query: 1067 FEFLQTICNHEHYIPLNLPM------AFAKPKLQRVQDSNLEYS-------------LSD 1107
EF + +C+HEHY+ LNLP A P + + +S LS
Sbjct: 1042 MEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSSTFSSQAPDPKVTSMFELSG 1101
Query: 1108 EYCKHHFLVGLLLRETSIALQDNYE----IRYTAISVIKNLLIKHAFDTRYQHKNQQAKI 1163
+ + HFL GLLL E ++AL+ E + AIS + +LL H D RY +A++
Sbjct: 1102 PFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAVHSLLCGHDTDPRYAEATVKARV 1161
Query: 1164 AQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFTSPANRGSLST--DKDT 1221
A+LYLP + + + + RL +F G P R L++ D DT
Sbjct: 1162 AELYLPLLSIARDTLPRL------------------HDFAEG---PGQRSRLASMLDSDT 1200
Query: 1222 AYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTRQSSTRSSVSQYNR---LDQYE 1278
G G D G++ P A G +R S ++ + L
Sbjct: 1201 ------EGEG----DIAGTINPSVAMAIAG-GPLAPGSRASISQGPPTASRAGCALSAES 1249
Query: 1279 IRSLLMCYLYIVKMISEDTLLTYW-NKVSPQELINILILLEVCLFHFRYMGKRNIARVHD 1337
R+LL C L+++K +E LL W ++ +L +L LL +CL F Y GK+ R++
Sbjct: 1250 SRTLLACVLWVLKN-TEPALLQRWATDLTLPQLGRLLDLLYLCLAAFEYKGKKAFERINS 1308
Query: 1338 AWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSF----------TLNHSSTT-- 1385
K +D K++ A+ G Q ++ S S F ++ H T
Sbjct: 1309 LTFKK--SLDMKARLEEAILGTIGARQEMVRR-SRERSPFGNPENVRWRKSVTHWKQTSD 1365
Query: 1386 ----TEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHL 1441
T+ ++ H+AL+EGN ATE SL VLDT+ Q ++ ++ ++ V + L
Sbjct: 1366 RVDKTKDEMEHEALVEGNLATEASLVVLDTLEIIVQT----VMLSEARESVLGAVLKVVL 1421
Query: 1442 AFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEA 1501
L + QS + L+H A+ RA +SKFP F+ +CA C +L+ C S+IS+ R A
Sbjct: 1422 YSLGSAQSALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHA 1481
Query: 1502 SALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSD 1561
SA LYLLMR NFE F R +Q+ +++S L+ + SL I +A D
Sbjct: 1482 SASLYLLMRQNFEIGHN--FARVKMQVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEED 1539
Query: 1562 RPMKATAFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTW 1621
++ + F +V+DL + +L T +MKEH++DPEMLIDL Y +A+ Y +P+LR TW
Sbjct: 1540 MGLRDSTFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLIDLMYRIARGYQGSPDLRLTW 1599
Query: 1622 LDSMAKIHVKNGDFSEAAMCYVHVAALVAEFL-----HRKKLFPNGCSAFKKITPNIDEE 1676
L +MA H + G+ +EAA C VH AALVAE+L HR P GC +F+ I+ N+ EE
Sbjct: 1600 LQNMAGKHAELGNHAEAAQCMVHAAALVAEYLALLEDHRH--LPVGCVSFQNISSNVLEE 1657
Query: 1677 GAMKEDAGMMDV-------HYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKR 1729
A+ +D D H++E L+ LLEQ YE ++E+ K ++PI E
Sbjct: 1658 SAISDDILSPDEEGFCSGKHFTELGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAH 1717
Query: 1730 REFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKL 1789
R+++KL V+ L A+TKI+ +R+ GT+FRV FYG + F + D +E++YKEP +
Sbjct: 1718 RDYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYG-AHFGDLDEQEFVYKEPSI 1776
Query: 1790 TGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTE 1849
T L+EIS RL + Y E+FG + V+II+DS+ V+ +LD + A+IQ+TYV+PYFD EL +
Sbjct: 1777 TKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKSKLDSQKAYIQITYVEPYFDTYELKD 1836
Query: 1850 RKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQ 1909
R T F+RN+ + F+F P+T G+ G + EQ KR+T+L+T ++FPY+K RI + ++
Sbjct: 1837 RVTYFDRNYGLRTFLFCTPFTPDGRAHGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREE 1896
Query: 1910 INLKPIDVATDEIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLND 1969
L P++VA ++++ KT EL D LQ+ LQG V VN GPL A+ FL +
Sbjct: 1897 TVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLAE 1956
Query: 1970 SQASKYPPKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSD 2029
+ ++L+ F+ F + C AL N+ LI DQ EYH L+ N+ + + L
Sbjct: 1957 IPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERNYCRLREALQP 2016
Query: 2030 IIHEQILQEDTMHSPWMSNTLH 2051
++ +++ Q P + N+L+
Sbjct: 2017 LLTQRLPQLMAPTPPGLRNSLN 2038
Score = 74.7 bits (182), Expect = 9e-13
Identities = 51/167 (30%), Positives = 87/167 (52%), Gaps = 18/167 (10%)
Query: 2 AEVRKFTKRLSKPGTAAELRQSVSEAVRGS----------VVLEKAKVVEPLDYENVIAQ 51
+E R F ++++ AAE+R+ VS GS + + +VVEPLD+E+V+
Sbjct: 4 SERRAFAHKINRT-VAAEVRKQVSRERSGSPHSSRRCSSSLGVPLTEVVEPLDFEDVLLS 62
Query: 52 RKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTD 111
R PLRDL+ FP +D+ + + R+ RT + +P+D + AQ V+ ++ Y D
Sbjct: 63 RPPDAEPGPLRDLVEFPADDLELLLQPRECRTTEPGIPKDEKLDAQ---VRAAVEMYIED 119
Query: 112 WHVVNYKYEDFSGDFRMLPCKSLRPEK--IPNHVFEIDEDCEKDEDS 156
W +V+ +Y+ S + + + R + +P VFE +D DE S
Sbjct: 120 WVIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFE--QDASGDERS 164
>gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]
Length = 2109
Score = 625 bits (1612), Expect = e-178
Identities = 390/1185 (32%), Positives = 615/1185 (51%), Gaps = 124/1185 (10%)
Query: 928 PQAQLIHETLATTMIAI---LKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKL 984
P +L HE LA + +++SA L+ +WFFFE++ KSM +L +K++
Sbjct: 949 PTKKLFHEELALQWVVCSGSVRESA--------LQQAWFFFELMVKSMVHHLYFNDKLEA 1000
Query: 985 PRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFIF 1044
PR RFPE + + +L+ I + R+ + + +N SLA FL L++MDRGF+F
Sbjct: 1001 PRKSRFPERFMDDIAALVSTIASDIVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVF 1060
Query: 1045 NLINDYISGFSPK-----DPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQ----- 1094
+LI S K +P VL + +FL+ IC+HEHY+ LNLP + P
Sbjct: 1061 SLIKSCYKQVSSKLYSLPNPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSV 1120
Query: 1095 ------------RVQDSNLE--YSLSDEYCKHHFLVGLLLRETSIALQDNYE----IRYT 1136
VQD + + LS + + H+L GL+L E ++ L + E +
Sbjct: 1121 SSATSQSSGFSTNVQDQKIANMFELSVPFRQQHYLAGLVLTELAVILDPDAEGLFGLHKK 1180
Query: 1137 AISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNS 1196
I+++ NLL H D RY +A++A LYLP +G+++E + +L ++ P
Sbjct: 1181 VINMVHNLLSSHDSDPRYSDPQIKARVAMLYLPLIGIIMETVPQLYDFTETHNQRGRPIC 1240
Query: 1197 ASRDEFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTG 1256
+ D++ E GS+I + +
Sbjct: 1241 IATDDY--------------------------------ESESGSMISQTVAMAIAGTSVP 1268
Query: 1257 ENTRQSS---TRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINI 1313
+ TR S T +S Q+ RSLL+C L+++K E L ++ +S +L +
Sbjct: 1269 QLTRPGSFLLTSTSGRQHTTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRL 1328
Query: 1314 LILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSL 1373
L LL +C+ F Y GK+ R++ K D +++ A+ G Q ++
Sbjct: 1329 LDLLYLCVSCFEYKGKKVFERMNSLTFKK--SKDMRAKLEEAILGSIGARQEMVRRSRGQ 1386
Query: 1374 ESSFTL-------------------------NHSSTTTE------ADIFHQALLEGNTAT 1402
++T+ H TE A+I H+AL++GN AT
Sbjct: 1387 LGTYTIASPPERSPSGSAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLAT 1446
Query: 1403 EVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRA 1462
E +L +LDT+ Q + ++ V + L + QS V L+H FA+ RA
Sbjct: 1447 EANLIILDTLEIVVQTVSV----TESKESILGGVLKVLLHSMACNQSAVYLQHCFATQRA 1502
Query: 1463 FISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFL 1522
+SKFP F+ CA C +L+ C+S I + R+ ASA LYLLMR NFE F
Sbjct: 1503 LVSKFPELLFEEETEQCADLCLRLLRHCSSSIGTIRSHASASLYLLMRQNFEIGNN--FA 1560
Query: 1523 RTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRT 1582
R +Q+ +++S L+ + SL I +A D ++ T FP +V+DL +
Sbjct: 1561 RVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHM 1620
Query: 1583 VLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCY 1642
+L T +MKEH++DPEMLIDL Y +AK Y ++P+LR TWL +MA H + + +EAA C
Sbjct: 1621 ILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCL 1680
Query: 1643 VHVAALVAEFLHR---KKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDV-------HYSE 1692
VH AALVAE+L +K P GC F+ I+ N+ EE A+ +D D +++E
Sbjct: 1681 VHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTE 1740
Query: 1693 EVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEV 1752
L+ LLEQ A YE ++E+ K+++PI+E R+ +KL+ ++ L A++KI+
Sbjct: 1741 SGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQ 1800
Query: 1753 MHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENV 1812
+R+ GT+FRV FYG F + D +E++YKEP +T L+EIS RL YGE+FG + V
Sbjct: 1801 STGWERMFGTYFRVGFYGTKF-GDLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVV 1859
Query: 1813 KIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNISRFVFEAPYTLS 1872
++I+DS+ V+ +LDP A+IQ+TYV+PYFD E+ +R T F++N+N+ RF++ P+TL
Sbjct: 1860 EVIKDSNPVDKCKLDPNKAYIQITYVEPYFDTYEMKDRITYFDKNYNLRRFMYCTPFTLD 1919
Query: 1873 GKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKL 1932
G+ G + EQ KR+TILTTS++FPY+K R+ + +++I L PI+VA ++++ KT EL
Sbjct: 1920 GRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFA 1979
Query: 1933 CSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQ 1992
D LQ+ LQG V VN GPL A+ FL++ + + ++L+ F+ F +
Sbjct: 1980 THQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLFRHHNKLRLCFKDFTK 2039
Query: 1993 ACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQ 2037
C AL N+ LI DQ EY L+ N+ + + L +I+ +I Q
Sbjct: 2040 RCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQ 2084
Score = 262 bits (670), Expect = 2e-69
Identities = 204/651 (31%), Positives = 317/651 (48%), Gaps = 133/651 (20%)
Query: 354 PDIKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISA 413
PDI +E +R LV C L F I +EP F +LAL+DVK KIS
Sbjct: 254 PDIP--KEHFGQRLLVKCLSLKFEI-------------EIEPIFASLALYDVKEKKKISE 298
Query: 414 DFHVDLNPPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHP 473
+F+ DLN ++ +L + P + I +A S IFS+T P
Sbjct: 299 NFYFDLNSEQMKGLL-------------RPHVPPAAITTLARS-------AIFSITYPSQ 338
Query: 474 EIFLVARIEKVLQ-GNITHCAEPYI--KNSDPVKTAQKVHRT---AKQVCSRLGQYRMPF 527
++FLV ++EKVLQ G+I CAEPY+ K +D K +K+ + A Q C RLG+YRMPF
Sbjct: 339 DVFLVIKLEKVLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPF 398
Query: 528 AWAARPIFK--DTQGSLDLD------------------------GR-------------- 547
AW A + + GSL+ D GR
Sbjct: 399 AWTAIHLMNIVSSAGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACN 458
Query: 548 ---FSP-------LYKQDSSKLSSEDILKLLSEYKKPEKT--KLQIIPGQLNITVECVPV 595
F P +KQ+ +LS ED+ K L++ ++P +L+ I QL I + P
Sbjct: 459 LTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPE 518
Query: 596 DLSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQ 655
+ C+T + +K + + T E+ EF P Y P T Y+N LY+YP L + ++
Sbjct: 519 NPHYCLTPELLQVKLYPDSRVRPTREILEF-PARDVYV-PNTTYRNLLYIYPQSLNFANR 576
Query: 656 KTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIK 715
+ ARNI V V+F E ++A+ I+GK + S F+ AY V +HN++P+F++EIK
Sbjct: 577 Q--GSARNITVKVQFMYG-EDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIK 633
Query: 716 IELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDT-VETPVGFAWVPLLKDGRIITFEQQ 774
++LP L HHLLFTFYHVSC+ +KQ+T +ETPVG+ W+P+L++GR+ T +
Sbjct: 634 VKLPATLTDHHHLLFTFYHVSCQ-------QKQNTPLETPVGYTWIPMLQNGRLKTGQFC 686
Query: 775 LPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFF-- 832
LPVS PP ++ E +KWVD K + ++ S+I+TQD ++ KFF
Sbjct: 687 LPVSLEKPPQAYSVLSPEVPLP---GMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFAL 743
Query: 833 -----HHCQLIQSGSKEV-----PGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNM 882
H ++ G + EL + L++ +++ +++FL ++L +L ++
Sbjct: 744 VNALDEHLFPVRIGDMRIMENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVIRP 803
Query: 883 THEDDVPINCTM----VLLHIVSKCH--------EEGLDSYLRSFIKYSFR 921
+N + I+++ H + G +S L S+I Y FR
Sbjct: 804 PVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGRNSLLASYIHYVFR 854
Score = 81.3 bits (199), Expect = 9e-15
Identities = 55/166 (33%), Positives = 83/166 (50%), Gaps = 22/166 (13%)
Query: 1 MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEK----------------AKVVEPLD 44
MAE R F +++S+ AAE+R+ +S GS L K + V+P+D
Sbjct: 1 MAERRAFAQKISRT-VAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVD 59
Query: 45 YENVIAQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKEC 104
E+ + + S PLRDL+ FP +DI + R RT+ S VPE++E V++C
Sbjct: 60 LEDYLITHPLAVDSGPLRDLIEFPPDDIEVVYSPRDCRTLVSAVPEESE---MDPHVRDC 116
Query: 105 IKTYSTDWHVVNYKYEDFSGDF--RMLPCKSLRPEKIPNHVFEIDE 148
I++Y+ DW +V KY F L + R + +P VFE DE
Sbjct: 117 IRSYTEDWAIVIRKYHKLGTGFNPNTLDKQKERQKGLPKQVFESDE 162
>gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
Length = 2099
Score = 588 bits (1517), Expect = e-167
Identities = 392/1173 (33%), Positives = 601/1173 (51%), Gaps = 112/1173 (9%)
Query: 922 PEKPSAPQA---QLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLE 978
P P+AP+ + HE LA M+ + + KY+WFFFE++ KSMA ++
Sbjct: 946 PSSPAAPRPASKKHFHEELALQMVVSTGMVRE-----TVFKYAWFFFELLVKSMAQHVHN 1000
Query: 979 ENKIKLPRGQRFPETYHHVLHSLLLAIIPHVT---IRYAEIPDESRNVNYSLASFLKRCL 1035
+K R RF + + + +++ + + ++ + +++ +N SLA FL L
Sbjct: 1001 MDKRDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLL 1060
Query: 1036 TLMDRGFIFNLINDYISGFSPK--DPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAK--- 1090
+LMDRGF+FNLI Y S S K + L + EFL+ +C+HEHY+ LNL A
Sbjct: 1061 SLMDRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAP 1120
Query: 1091 ----PKLQRVQDSNLE----------YSLSDEYCKHHFLVGLLLRETSIALQDNYE---- 1132
P + S+ + L+ EY + HFL GLL E + AL E
Sbjct: 1121 TSPCPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISK 1180
Query: 1133 IRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAA 1192
++ A+S I +LL H D R + KIA LYLP VG++L+ + +L
Sbjct: 1181 VQRKAVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQL----------- 1229
Query: 1193 MPNSASRDEFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQ 1252
C FT R ++ D E+ G+
Sbjct: 1230 -----------CDFTVADTRRYRTSGSD--------------EEQEGAGAINQNVALAIA 1264
Query: 1253 GNTGENTRQSSTRSSV--SQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQEL 1310
GN SS+ QYN L+ R+L++C+L+I+K ++ +L+ W P
Sbjct: 1265 GNNFNLKTSGIVLSSLPYKQYNMLNADTTRNLMICFLWIMKN-ADQSLIRKWIADLPSTQ 1323
Query: 1311 IN-ILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQH 1369
+N IL LL +C+ F Y GK++ +V L K D K++ AL G ++
Sbjct: 1324 LNRILDLLFICVLCFEYKGKQSSDKVSTQVLQK--SRDVKARLEEALLRGEGARGEMMRR 1381
Query: 1370 LSSLESSFT-----------------LNHSSTTTEADIFHQALLEGNTATEVSLTVLDTI 1412
+ F N T+A++ +AL+ GN ATE L +LD
Sbjct: 1382 RAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQ 1441
Query: 1413 SFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFF 1472
Q D + L+ V + + L QS L H FA+LRA I+KF F
Sbjct: 1442 ENIIQASSAL----DCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLF 1497
Query: 1473 KGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAV 1532
+ V C C++VL C+S + TR++A A LYLLMR +F T F R +Q+ +++
Sbjct: 1498 EEEVEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATSN--FARVKMQVTMSL 1555
Query: 1533 SQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMKE 1592
+ L+ + SL I ++ D M+ T FP +V++L + ++L T +M+E
Sbjct: 1556 ASLVGRAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELLCNLNSILYDTVKMRE 1615
Query: 1593 HEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEF 1652
++DPEML+DL Y +AKSY ++P+LR TWL +MA+ H K ++EAAMC VH AALVAE+
Sbjct: 1616 FQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEY 1675
Query: 1653 LHRKK---LFPNGCSAFKKITPNIDEEGAMKEDAGMMDV-------HYSEEVLLELLEQC 1702
L + P G +F+ I+ N+ EE + ED D +++E L+ LLEQ
Sbjct: 1676 LSMLEDHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQA 1735
Query: 1703 VDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGT 1762
+ YE ++E+ KL++PI E REF KLT + L A+ I+ H KR+ GT
Sbjct: 1736 AELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDH--KRMFGT 1793
Query: 1763 FFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVN 1822
+FRV F+G S F + D +E++YKEP +T L EIS RL YG+ FG E V++I+DS V+
Sbjct: 1794 YFRVGFFG-SKFGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVD 1852
Query: 1823 AKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQ 1882
+LDP A+IQ+T+V+PYFD+ E+ +R T FE+N N+ RF++ P+TL G+ +G + EQ
Sbjct: 1853 KTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQ 1912
Query: 1883 CKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKLCSSTDVDMIQ 1942
+R T+LTT ++FPY+K RI + +++ L PI+VA +++K KT +L + D
Sbjct: 1913 YRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKM 1972
Query: 1943 LQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQACSIALELNE 2002
LQ+ LQG V VN GPL A+ FL + A + ++L+ F++FI C A+E N+
Sbjct: 1973 LQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNK 2032
Query: 2003 RLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQI 2035
RLI DQ EY + LK N+ + + L +I +I
Sbjct: 2033 RLITADQREYQQELKKNYNKLKENLRPMIERKI 2065
Score = 286 bits (733), Expect = 1e-76
Identities = 220/699 (31%), Positives = 337/699 (48%), Gaps = 135/699 (19%)
Query: 323 EQLNKLSRGDGRQ-NLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLTFNILGQ 381
E+ N+ +R RQ LF+ V D I P + +E R LV L F I
Sbjct: 223 EKQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEI--- 279
Query: 382 IGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGSSTQLASDGSP 441
+EP F ++AL+DVK KIS +FH DLN + L + +A
Sbjct: 280 ----------EIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVA----- 324
Query: 442 KGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQ-GNITHCAEPY--IK 498
A SQ R +FSVT P +I+LV +IEKVLQ G I CAEPY IK
Sbjct: 325 ------------ASSQAR---SAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIK 369
Query: 499 NSDPVKTAQKVHRT---AKQVCSRLGQYRMPFAWAARPI--------------------- 534
SD K+ +K+ + A+ C RLG+YRMPFAWA +
Sbjct: 370 ESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVG 429
Query: 535 ---------------FKDTQGSLDLDG----------RFSPLYKQDSSKLSSEDILKLLS 569
+ SL+ +G S +KQ+ +LS ED+ K L+
Sbjct: 430 RSSVGERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLA 489
Query: 570 EYKKPEKTKLQI--IPGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNITVEVEEFVP 627
+YK+ + ++ IPG L + + P ++ C+T +P+KPF +N E+ EF P
Sbjct: 490 DYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPENRTRPHKEILEF-P 548
Query: 628 EMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGK 687
Y P T+Y+N LYVYP +L + ++ A ARNI + ++F +++ ++A+ I+GK
Sbjct: 549 TREVYV-PHTVYRNLLYVYPQRLNFVNK--LASARNITIKIQFMCGEDA-SNAMPVIFGK 604
Query: 688 PAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKK 747
+G F Y V++HN++P+FY+E+KI+LP L HHLLFTFYH+SC+ K+
Sbjct: 605 SSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQ------QKQ 658
Query: 748 QDTVETPVGFAWVPLLKDGRIITFEQQLPVS-ANLPPGYLNLNDAESRRQCNVDIKWVDG 806
+VET +G++W+P+L + R+ T LPV+ LPP Y +++ AE N IKW +G
Sbjct: 659 GASVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNY-SMHSAEKVPLQNPPIKWAEG 717
Query: 807 AKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQS-------------GSKEVPGELIKYL 853
K + I+ S+++TQD H+ KFF C ++S + EL +
Sbjct: 718 HKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSI 777
Query: 854 KCLHAMEIQVMIQFLPVILMQLFRV-------------LTNMTHEDDVPINCTMVLLHIV 900
CL++ ++ ++ FL ++L +LF++ + E V I ++ +
Sbjct: 778 ICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDL 837
Query: 901 SKCHEEGLDSYLRSFIKYSFR-PE------KPSAPQAQL 932
SK + G + L S++ Y FR PE K AP A L
Sbjct: 838 SK-DQHGRNCLLASYVHYVFRLPEVQRDVPKSGAPTALL 875
Score = 45.8 bits (107), Expect = 4e-04
Identities = 34/119 (28%), Positives = 62/119 (52%), Gaps = 7/119 (5%)
Query: 2 AEVRK-FTKRLSKPGTAAELRQSVSEAVRGSVVLEKA-KVVEPLDYENVIAQRKTQIYSD 59
AE+RK FT P RQS+S + S+ L + VEP+D+E ++ +
Sbjct: 22 AEIRKQFTL---PPNLGQYHRQSISTSGFPSLQLPQFYDPVEPVDFEGLLMTHLNSLDVQ 78
Query: 60 PLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYK 118
++L F +D+ + ++ RT+Q ++PE+ + V++C++TY +W +VN K
Sbjct: 79 LAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVE--LDPHVRDCVQTYIREWLIVNRK 135
>gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]
Length = 2030
Score = 92.4 bits (228), Expect = 4e-18
Identities = 90/434 (20%), Positives = 181/434 (41%), Gaps = 58/434 (13%)
Query: 1609 KSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVA-------EFLHRKKLFPN 1661
KS + E+ ++ + +H++ +++EAA + L+ EFLH +P+
Sbjct: 1228 KSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLH----YPS 1283
Query: 1662 GCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKL 1721
E KE +HY K + +E + +
Sbjct: 1284 ------------QTEWQRKEGLCRKIIHYFN---------------KGKSWEFGIPLCRE 1316
Query: 1722 IVPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKE 1781
+ YE +++ L+ + + Y I+E ++RL FFRV FYG+ F KE
Sbjct: 1317 LACQYESLYDYQSLSWIRKMEASYYDNIME----QQRLEPEFFRVGFYGRKFPFFLRNKE 1372
Query: 1782 YIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQ-VTYVKP 1840
Y+ + L R++ + + ++ D+ + D +Y I VT +
Sbjct: 1373 YVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDA----ILQCDAQYLQIYAVTPIPD 1428
Query: 1841 YFDDKELT---ERKTEFERNHNISRFVFEAPYTLSGK-KQGCIEEQCKRRTILTTSNSFP 1896
Y D ++ +R F R +N+ +F ++ P+ K K+ + RT LT ++S P
Sbjct: 1429 YVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIERTTLTLTHSLP 1488
Query: 1897 YVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKLCSSTDVDMIQ-----LQLKLQGCV 1951
+ + + + + + P++ A +++K EL+ L S + L + L G +
Sbjct: 1489 GISRWFEVERRELVEVSPLENAIQVVENKNQELRSLISQYQHKQVHGNINLLSMCLNGVI 1548
Query: 1952 SVQVNAGPLAYARAFLNDSQASKYP--PKKVSELKDMFRKFIQACSIALELNERLIKEDQ 2009
VN G Y AF + +K+P +K+++LK++ ++ + + L ++E+ + +
Sbjct: 1549 DAAVNGGIARYQEAFFDKDYINKHPGDAEKITQLKELMQEQVHVLGVGLAVHEKFVHPEM 1608
Query: 2010 VEYHEGLKSNFRDM 2023
H+ L F+ M
Sbjct: 1609 RPLHKKLIDQFQMM 1622
Score = 38.5 bits (88), Expect = 0.069
Identities = 67/320 (20%), Positives = 121/320 (37%), Gaps = 48/320 (15%)
Query: 676 SDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHV 735
+D LK +G ++ ++ V +H+ +P + + IK+ +PI + HL F F H
Sbjct: 453 ADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRH- 511
Query: 736 SCEINTKGTTKKQDTVETPVGFAWVPLLKDG---------RIITFEQQLPVSANLPPGYL 786
C KG K GFA+ L++D + ++ + N YL
Sbjct: 512 -CSTKDKGEKKL-------FGFAFSTLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYL 563
Query: 787 NL----NDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGS 842
L D + + K I + L ST TQ++ + L
Sbjct: 564 GLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDL--------LALLKW 615
Query: 843 KEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSK 902
K P ++ L L + + +++FL IL LF +L + T + + + ++V
Sbjct: 616 KAFPDRIMDVLGRLRHVSGEEIVKFLQDILDTLFVILDDNTEKYGLLVFQSLVF------ 669
Query: 903 CHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQ----SADFL---SIN 955
+ + LR + FRP + Q +I LK SA+ + I
Sbjct: 670 -----IINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQ 724
Query: 956 KLLKYSWFFFEIIAKSMATY 975
+ ++ + F+ I +S Y
Sbjct: 725 EAMRALEYLFKFIVQSRILY 744
>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
Length = 1966
Score = 79.3 bits (194), Expect = 4e-14
Identities = 69/340 (20%), Positives = 143/340 (42%), Gaps = 23/340 (6%)
Query: 1718 ISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEE 1777
+ + I YE ++ L+++ Y KI++ ++RL FFRV FYG+ F
Sbjct: 1275 LCRKIAEQYESYYDYRNLSKMRMMEASLYDKIMD----QQRLEPEFFRVGFYGKKFPFFL 1330
Query: 1778 DGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTY 1837
KE++ + L R++ + +Q +++ + + ++Q+
Sbjct: 1331 RNKEFVCRGHDYERLEAFQQRMLNEFPHAIA------MQHANQPDETIFQAEAQYLQIYA 1384
Query: 1838 VKPYFDDKELTERK------TEFERNHNISRFVFEAPYTLSGK-KQGCIEEQCKRRTILT 1890
V P + +E+ +R+ F + ++I +F ++ P+ K K+ + RT L
Sbjct: 1385 VTPIPESQEVLQREGVPDNIKSFYKVNHIWKFRYDRPFHKGTKDKENEFKSLWVERTSLY 1444
Query: 1891 TSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKLCSSTDVDMIQ----LQLK 1946
S P + + + + + + P++ A + +++K +L+ L S +Q L +
Sbjct: 1445 LVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQTRQMQNINPLTMC 1504
Query: 1947 LQGCVSVQVNAGPLAYARAFLNDSQASKYPP--KKVSELKDMFRKFIQACSIALELNERL 2004
L G + VN G Y AF +P +K++ L+++ + Q L ++E+
Sbjct: 1505 LNGVIDAAVNGGVSRYQEAFFVKEYILSHPEDGEKIARLRELMLEQAQILEFGLAVHEKF 1564
Query: 2005 IKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSP 2044
+ +D H+ L F M L +Q +H P
Sbjct: 1565 VPQDMRPLHKKLVDQFFVMKSSLGIQEFSACMQASPVHFP 1604
Score = 43.1 bits (100), Expect = 0.003
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 13/110 (11%)
Query: 661 ARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPI 720
ARN+ V + DS LK +G + ++ V +HN +P + + +K+ +P+
Sbjct: 421 ARNVEVTMFIVDSS---GQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPV 477
Query: 721 HLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLL-KDGRII 769
+ H+ F F H C KG K GF++VPL+ +DGR +
Sbjct: 478 DKFRGAHIRFEFRH--CSTKEKGEKKL-------FGFSFVPLMQEDGRTL 518
>gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
Length = 1870
Score = 71.2 bits (173), Expect = 1e-11
Identities = 72/349 (20%), Positives = 149/349 (42%), Gaps = 14/349 (4%)
Query: 1688 VHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRR-EFEKLTQVYRTLHGAY 1746
V+ +E+ +L ++ + K + +E ++SK + YE + ++E L + + Y
Sbjct: 1290 VYTQQELKEKLYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFY 1349
Query: 1747 TKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEK 1806
I++ M + +F V +YGQ F K +IY+ + + SLRL+ +
Sbjct: 1350 ENIIKAMRPQPE----YFAVGYYGQGFPSFLRNKIFIYRGKEYERREDFSLRLLTQFPNA 1405
Query: 1807 FGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNISRFVFE 1866
+ + K + K+ + V + P + DK + E+ + R + + +F +
Sbjct: 1406 EKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQILNYYRANEVQQFRYS 1465
Query: 1867 APYTLSGKKQGCIE--EQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPID--VATDEI 1922
P+ G+K E RT TT+ +FP + K + + P++ + T E+
Sbjct: 1466 RPFR-KGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQISTEEISPLENAIETMEL 1524
Query: 1923 KDKTAE--LQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYP--PK 1978
++ +Q+ + + L + L G V V G Y +AF + ++P +
Sbjct: 1525 TNERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKAFFTEKYLQEHPEDQE 1584
Query: 1979 KVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKEL 2027
KV LK + + + + ++ + E HE L S FR++ +++
Sbjct: 1585 KVELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKEKV 1633
Score = 38.5 bits (88), Expect = 0.069
Identities = 69/357 (19%), Positives = 144/357 (40%), Gaps = 44/357 (12%)
Query: 640 KNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYA 699
+N +YV + ++D K +N+ V + D + L+ AG + +
Sbjct: 443 RNDIYVTLIHGEFDKGKK-KTPKNVEVTMSVHDEE---GKLLEKAIHPGAGYEGISEYKS 498
Query: 700 VVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAW 759
VV + + P +Y+ +K+ + I + H+ FTF H + + + +D E G A+
Sbjct: 499 VVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRH-------RSSQETRDKSERAFGVAF 551
Query: 760 VPL-------LKDGR--IITFE------QQLPVSANLPPGYLNLNDAESRRQCNV--DIK 802
V L L+DGR ++ ++ + LP + + + E + N+
Sbjct: 552 VKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFTP 611
Query: 803 WVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQ 862
D K +I + + ST TQ++ + + +S S+ + L K ++ ++
Sbjct: 612 SKDSTKDSFQIATLICSTKLTQNVDLLGLLNW----RSNSQNIKHNLKKLME----VDGG 663
Query: 863 VMIQFLPVILMQLFRVLTNMTHE---DDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYS 919
+++FL L LF ++ M+ D + + + ++ ++ + + L ++I
Sbjct: 664 EIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYIYKH 723
Query: 920 FRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEIIAKSMATYL 976
F SA A + + +A S+ + LK + F I +S YL
Sbjct: 724 F-----SATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYL 775
>gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
Length = 1865
Score = 69.3 bits (168), Expect = 4e-11
Identities = 69/344 (20%), Positives = 146/344 (42%), Gaps = 23/344 (6%)
Query: 1697 ELLEQCVDGLWKAERYEIISEISKLIVPIYEKRR-EFEKLTQVYRTLHGAYTKILEVMHT 1755
+L ++ + K + +E + K + YE ++E+L+++ + Y I++V+
Sbjct: 1275 QLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRP 1334
Query: 1756 KKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKII 1815
K +F V +YGQ F GK +IY+ + + RL+ + N + +
Sbjct: 1335 KP----DYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQF------PNAEKM 1384
Query: 1816 QDSDKVNAKELDPKYAHIQVTYVKPYFD-----DKELTERKTEFERNHNISRFVFEAPYT 1870
+ + + +IQ VKP D + ++E+ F R + + RF + P
Sbjct: 1385 KTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIR 1444
Query: 1871 LSGKK-QGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIK---DK- 1925
K RTI TT+ P + + + + + P++ A + ++ DK
Sbjct: 1445 KGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKI 1504
Query: 1926 TAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPP--KKVSEL 1983
+ +Q+ + + L + L G V V G Y +AF D ++P +K+ +L
Sbjct: 1505 NSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKL 1564
Query: 1984 KDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKEL 2027
KD+ I + + ++ + E +HE +++ F+ + +++
Sbjct: 1565 KDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKV 1608
Score = 42.0 bits (97), Expect = 0.006
Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 13/126 (10%)
Query: 640 KNHLYVYPLQLKYDS-QKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAY 698
+N +YV +Q +D KT AK N+ V V D D L+ + AG +
Sbjct: 425 RNDIYVTLVQGDFDKGSKTTAK--NVEVTVSVYDED---GKRLEHVIFPGAGDEAISEYK 479
Query: 699 AVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFA 758
+V+ + + P +++ +K+ +PI + HL FTF H + + +D E A
Sbjct: 480 SVIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRH-------RSSQDSKDKSEKIFALA 532
Query: 759 WVPLLK 764
+V L++
Sbjct: 533 FVKLMR 538
>gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]
Length = 1830
Score = 59.3 bits (142), Expect = 4e-08
Identities = 67/346 (19%), Positives = 145/346 (41%), Gaps = 29/346 (8%)
Query: 1695 LLELLEQCVDGLW-KAERYEIISEISKLIVPIYEKRR-EFEKLTQVYRTLHGAYTKILEV 1752
L E L + + G + K + +E + K + YE ++E L+Q Y I+++
Sbjct: 1276 LKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKI 1335
Query: 1753 MHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLY--GEKFGTE 1810
+ K +F V +YGQ F K +IY+ + + ++L+ + EK T
Sbjct: 1336 LRPKP----DYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMTQFPNAEKMNTT 1391
Query: 1811 NVKIIQDSDKVNAKELDPKYAHIQ-VTYVKPYFDDKELTERKTEFERNHNISRFVFEAPY 1869
+ D NA + +Q V P F +K + ++ F +++ + RF + P
Sbjct: 1392 SAP---GDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPV 1448
Query: 1870 TLSGKKQGCIEEQCK------RRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIK 1923
++G ++ + + RT T+ P + + + Q + P++ A + +
Sbjct: 1449 -----RRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMS 1503
Query: 1924 DKTAELQKLCSSTDVD----MIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPK- 1978
++ + + D + L + L G V V G Y +AF + +P
Sbjct: 1504 TANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQ 1563
Query: 1979 -KVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDM 2023
K++ LKD+ I ++++E+ + ++ +H+ ++ F+++
Sbjct: 1564 DKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNL 1609
Score = 37.4 bits (85), Expect = 0.15
Identities = 84/362 (23%), Positives = 145/362 (40%), Gaps = 56/362 (15%)
Query: 640 KNHLYVYPLQLKYDS-QKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAY 698
+N +Y+ LQ +D KT + + +CV D + KP N Y
Sbjct: 423 RNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPM------NEY 476
Query: 699 -AVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYH-VSCEINTKGTTK---------K 747
+VV + + P + + +K+ +PI Q+ HL F F H S E KG K
Sbjct: 477 RSVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMK 536
Query: 748 QDTVETPVGFAWVPLLKDGRIITFEQQLPVSANLP-PGYL----NLNDAESRRQCNVDIK 802
+D GF + +LK ++ SA L P Y N SR +V
Sbjct: 537 EDGTTLHDGFHDLVVLKGDS----KKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGL 592
Query: 803 WVDGAKPLLKIKSHLESTIYTQD---LHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAM 859
V ++ + I + + ST TQ+ L + K+ QL+Q E ++ LK +
Sbjct: 593 SV-SSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQLLQ--------ENLEKLKIVDGE 643
Query: 860 EIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHE---EGLDSYLRSFI 916
E+ ++FL L LF ++ + D+ I L++I+ + + ++ L ++I
Sbjct: 644 EV---VKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLEAYI 700
Query: 917 KYSFRPEKPSAPQAQLIHETLATTMIAILKQSA---DFLSINKLLKYSWFFFEIIAKSMA 973
+ F A L ++ L T + L S+ I + LK + F+ I +S
Sbjct: 701 QQHF--------SATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYVFKFIVRSRT 752
Query: 974 TY 975
+
Sbjct: 753 LF 754
>gi|219689123 pleckstrin homology domain containing, family A member
5 isoform 2 [Homo sapiens]
Length = 1105
Score = 47.0 bits (110), Expect = 2e-04
Identities = 36/134 (26%), Positives = 68/134 (50%), Gaps = 14/134 (10%)
Query: 166 VIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDA 225
V+++GWL+K + + MK++K+R+F L+ L L Y+DEK + G I L +
Sbjct: 62 VVRRGWLYKQD-----STGMKLWKKRWFVLSDL-----CLFYYRDEKE-EGILGSILLPS 110
Query: 226 CIDVVQCPK---MRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEK 282
+ + R++AF+ + ++Y +T +EME W+ + + T+ + +
Sbjct: 111 FQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVD 170
Query: 283 KETVETAQDDETSS 296
K T E A ET++
Sbjct: 171 KITSENAPTKETNN 184
>gi|19923493 pleckstrin homology domain containing, family A member
5 isoform 1 [Homo sapiens]
Length = 1116
Score = 47.0 bits (110), Expect = 2e-04
Identities = 36/134 (26%), Positives = 68/134 (50%), Gaps = 14/134 (10%)
Query: 166 VIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDA 225
V+++GWL+K + + MK++K+R+F L+ L L Y+DEK + G I L +
Sbjct: 170 VVRRGWLYKQD-----STGMKLWKKRWFVLSDL-----CLFYYRDEKE-EGILGSILLPS 218
Query: 226 CIDVVQCPK---MRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEK 282
+ + R++AF+ + ++Y +T +EME W+ + + T+ + +
Sbjct: 219 FQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWMKAMLDAALVQTEPVKRVD 278
Query: 283 KETVETAQDDETSS 296
K T E A ET++
Sbjct: 279 KITSENAPTKETNN 292
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 45.1 bits (105), Expect = 7e-04
Identities = 36/145 (24%), Positives = 73/145 (50%), Gaps = 11/145 (7%)
Query: 163 KGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIY 222
K +KQGWLHK S+ T++ + +K+R+F L Q S ++ Y + + ++ KG +
Sbjct: 1210 KQEALKQGWLHKKGGGSS-TLSRRNWKKRWFVLRQ----SKLM--YFENDSEEKLKGTVE 1262
Query: 223 LDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEK 282
+ +++ + + ++ M D+ H L AE+ ++ +W L + + +TD +QE
Sbjct: 1263 VRTAKEIID-NTTKENGIDIIMADRTFH-LIAESPEDASQWFSVLSQ-VHASTDQEIQEM 1319
Query: 283 KETVETAQDD-ETSSQGKAENIMAS 306
+ Q+ T G +++ AS
Sbjct: 1320 HDEQANPQNAVGTLDVGLIDSVCAS 1344
Score = 32.0 bits (71), Expect = 6.5
Identities = 40/174 (22%), Positives = 77/174 (44%), Gaps = 34/174 (19%)
Query: 127 RMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMK 186
R+L C + PE++ + + + ++ + + + Q+ I +GWLHK NS ++K
Sbjct: 1360 RVLHCNADTPEEMHHWITLL----QRSKGDTRVEGQE--FIVRGWLHKEVKNSPKMSSLK 1413
Query: 187 VFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKM----------- 235
+ K+R+F LT L+ YK + + G + L++ VV +
Sbjct: 1414 L-KKRWFVLTH-----NSLDYYKSSEKNALKLGTLVLNSLCSVVPPDEKIFKETGYWNVT 1467
Query: 236 ---RRHAFEL--KMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKE 284
R+H + L K+L++ + + +A + K I T L+Q+ KE
Sbjct: 1468 VYGRKHCYRLYTKLLNEATRWSSAIQN------VTDTKAPIDTPTQQLIQDIKE 1515
>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
sapiens]
Length = 645
Score = 45.1 bits (105), Expect = 7e-04
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 32/181 (17%)
Query: 167 IKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDAC 226
IK GWL K +K +++RYF L + L YKDE+++K +GC+YL C
Sbjct: 48 IKMGWLKKQRS------IVKNWQQRYFVLR-----AQQLYYYKDEEDTKP-QGCMYLPGC 95
Query: 227 I--DVVQCPKMR-RHAFEL-------KMLDKYSHYLAAETEQEMEEWLITLKKIIQINTD 276
++ P+ + FE+ + + S+ L A ++ EMEEW+ L+++
Sbjct: 96 TIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCG 155
Query: 277 SLVQEKKETVETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQN 336
Q ETV Q +++ L ++++GR E + +L G+ N
Sbjct: 156 VFGQRLDETV-------AYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRL---PGQDN 205
Query: 337 L 337
L
Sbjct: 206 L 206
>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
sapiens]
Length = 638
Score = 45.1 bits (105), Expect = 7e-04
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 32/181 (17%)
Query: 167 IKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDAC 226
IK GWL K +K +++RYF L + L YKDE+++K +GC+YL C
Sbjct: 41 IKMGWLKKQRS------IVKNWQQRYFVLR-----AQQLYYYKDEEDTKP-QGCMYLPGC 88
Query: 227 I--DVVQCPKMR-RHAFEL-------KMLDKYSHYLAAETEQEMEEWLITLKKIIQINTD 276
++ P+ + FE+ + + S+ L A ++ EMEEW+ L+++
Sbjct: 89 TIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCG 148
Query: 277 SLVQEKKETVETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQN 336
Q ETV Q +++ L ++++GR E + +L G+ N
Sbjct: 149 VFGQRLDETV-------AYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRL---PGQDN 198
Query: 337 L 337
L
Sbjct: 199 L 199
>gi|62241015 AKT1 kinase [Homo sapiens]
Length = 480
Score = 43.9 bits (102), Expect = 0.002
Identities = 46/174 (26%), Positives = 73/174 (41%), Gaps = 28/174 (16%)
Query: 166 VIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDA 225
++K+GWLHK +K ++ RYF L DG++I YK+ + + +
Sbjct: 6 IVKEGWLHKRG------EYIKTWRPRYFLLKN--DGTFI--GYKERPQDVDQREAPLNN- 54
Query: 226 CIDVVQCPKM-----RRHAFELKMLD---KYSHYLAAETEQEMEEWLITLKKIIQINTDS 277
V QC M R + F ++ L ET +E EEW IQ D
Sbjct: 55 -FSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTA----IQTVADG 109
Query: 278 LVQEKKETVETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRG 331
L ++++E ++ + + G AE + SL + H M E E L L +G
Sbjct: 110 LKKQEEEEMDFRSGSPSDNSG-AEEMEVSLAKPKHRVTM---NEFEYLKLLGKG 159
>gi|62241013 AKT1 kinase [Homo sapiens]
Length = 480
Score = 43.9 bits (102), Expect = 0.002
Identities = 46/174 (26%), Positives = 73/174 (41%), Gaps = 28/174 (16%)
Query: 166 VIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDA 225
++K+GWLHK +K ++ RYF L DG++I YK+ + + +
Sbjct: 6 IVKEGWLHKRG------EYIKTWRPRYFLLKN--DGTFI--GYKERPQDVDQREAPLNN- 54
Query: 226 CIDVVQCPKM-----RRHAFELKMLD---KYSHYLAAETEQEMEEWLITLKKIIQINTDS 277
V QC M R + F ++ L ET +E EEW IQ D
Sbjct: 55 -FSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTA----IQTVADG 109
Query: 278 LVQEKKETVETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRG 331
L ++++E ++ + + G AE + SL + H M E E L L +G
Sbjct: 110 LKKQEEEEMDFRSGSPSDNSG-AEEMEVSLAKPKHRVTM---NEFEYLKLLGKG 159
>gi|62241011 AKT1 kinase [Homo sapiens]
Length = 480
Score = 43.9 bits (102), Expect = 0.002
Identities = 46/174 (26%), Positives = 73/174 (41%), Gaps = 28/174 (16%)
Query: 166 VIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDA 225
++K+GWLHK +K ++ RYF L DG++I YK+ + + +
Sbjct: 6 IVKEGWLHKRG------EYIKTWRPRYFLLKN--DGTFI--GYKERPQDVDQREAPLNN- 54
Query: 226 CIDVVQCPKM-----RRHAFELKMLD---KYSHYLAAETEQEMEEWLITLKKIIQINTDS 277
V QC M R + F ++ L ET +E EEW IQ D
Sbjct: 55 -FSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTA----IQTVADG 109
Query: 278 LVQEKKETVETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRG 331
L ++++E ++ + + G AE + SL + H M E E L L +G
Sbjct: 110 LKKQEEEEMDFRSGSPSDNSG-AEEMEVSLAKPKHRVTM---NEFEYLKLLGKG 159
>gi|238859653 pleckstrin homology domain containing family A member
4 isoform 2 [Homo sapiens]
Length = 583
Score = 40.0 bits (92), Expect = 0.024
Identities = 40/173 (23%), Positives = 71/173 (41%), Gaps = 21/173 (12%)
Query: 169 QGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACI- 227
+GWLHK + + ++++KRR+F L+ + L YKD + + I
Sbjct: 58 RGWLHKQDSSG-----LRLWKRRWFVLS-----GHCLFYYKDSREESVLGSVLLPSYNIR 107
Query: 228 -DVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETV 286
D P+ RR F + ++ LAA+T +++ WL L + + D Q +
Sbjct: 108 PDGPGAPRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPAR 167
Query: 287 ETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFS 339
+ G E + R + E+ ++ +LSRG GR L +
Sbjct: 168 PQPGEGPGGPGGPPE-----VSRGEEGRI----SESPEVTRLSRGRGRPRLLT 211
>gi|238859651 pleckstrin homology domain containing family A member
4 isoform 1 [Homo sapiens]
Length = 779
Score = 40.0 bits (92), Expect = 0.024
Identities = 40/173 (23%), Positives = 71/173 (41%), Gaps = 21/173 (12%)
Query: 169 QGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACI- 227
+GWLHK + + ++++KRR+F L+ + L YKD + + I
Sbjct: 58 RGWLHKQDSSG-----LRLWKRRWFVLS-----GHCLFYYKDSREESVLGSVLLPSYNIR 107
Query: 228 -DVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETV 286
D P+ RR F + ++ LAA+T +++ WL L + + D Q +
Sbjct: 108 PDGPGAPRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPAR 167
Query: 287 ETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFS 339
+ G E + R + E+ ++ +LSRG GR L +
Sbjct: 168 PQPGEGPGGPGGPPE-----VSRGEEGRI----SESPEVTRLSRGRGRPRLLT 211
>gi|18105042 GRB2-associated binding protein 2 isoform a [Homo
sapiens]
Length = 676
Score = 39.7 bits (91), Expect = 0.031
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 15/127 (11%)
Query: 164 GGVIKQGWLHKANVNSTITVTMKVFKRRYFYLT--QLPDGSYILNSYKDEKNSKESK--- 218
G V+ GWL K+ + +K+R+F L ++ +L YK++ + K +
Sbjct: 5 GDVVCTGWLRKSPPEKKLR--RYAWKKRWFILRSGRMSGDPDVLEYYKNDHSKKPLRIIN 62
Query: 219 --GCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQIN-- 274
C +DA + + F++K ++ + YL AETE++M +W+ ++ +I N
Sbjct: 63 LNFCEQVDAGLTFNKKELQDSFVFDIKTSER-TFYLVAETEEDMNKWVQSICQICGFNQA 121
Query: 275 ---TDSL 278
TDSL
Sbjct: 122 EESTDSL 128
>gi|239047795 pleckstrin homology domain containing, family A member
7 [Homo sapiens]
Length = 1121
Score = 38.9 bits (89), Expect = 0.053
Identities = 33/144 (22%), Positives = 65/144 (45%), Gaps = 33/144 (22%)
Query: 166 VIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDA 225
V+ +GWLHK + + M+++KRR+F L Y L YKD + + G I L +
Sbjct: 165 VVVRGWLHKQDSSG-----MRLWKRRWFVLAD-----YCLFYYKDSRE-EAVLGSIPLPS 213
Query: 226 CIDVVQCPK---MRRHAF-------------------ELKMLDKYSHYLAAETEQEMEEW 263
+ P+ R+++F + + ++Y +A+T+++M W
Sbjct: 214 YVISPVAPEDRISRKYSFKAVHTGMRALIYNSSTAGSQAEQSGMRTYYFSADTQEDMNAW 273
Query: 264 LITLKKIIQINTDSLVQEKKETVE 287
+ + + Q+ + S ++ E VE
Sbjct: 274 VRAMNQAAQVLSRSSLKRDMEKVE 297
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 38.9 bits (89), Expect = 0.053
Identities = 38/196 (19%), Positives = 82/196 (41%), Gaps = 11/196 (5%)
Query: 133 SLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLH----KANVNSTITVTMKVF 188
SL+ KI + ++ + + SS + S K+GWLH + + +++ +
Sbjct: 902 SLKGIKIADSQKSSEDSGSRKDSSSEVFSDAA---KEGWLHFRPLVTDKGKRVGGSIRPW 958
Query: 189 KRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDAC-IDVVQCPKMRRHAFELKMLDK 247
K+ Y L Y+ +++ E + I ++AC ID+ R++ F L D
Sbjct: 959 KQMYVVLRG--HSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDC 1016
Query: 248 YSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASL 307
+ AE +M W+ T+++ +N + ++ + + + KAE + +
Sbjct: 1017 ECLF-QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTP 1075
Query: 308 ERSMHPELMKYGRETE 323
+S+ G ++E
Sbjct: 1076 RQSLSIRQTLLGAKSE 1091
>gi|217416392 pleckstrin homology domain containing, family H (with
MyTH4 domain) member 2 [Homo sapiens]
Length = 1493
Score = 37.7 bits (86), Expect = 0.12
Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 11/153 (7%)
Query: 139 IPNHVFEIDEDCEKDEDS-SSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQ 197
IP + D + + E CS K L K+ ++ +K +KRR+F L
Sbjct: 670 IPPDAYSTDTEYSQPEQKLPKTCSSSSDNGKNEPLEKSGYLLKMSGKVKSWKRRWFVLK- 728
Query: 198 LPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETE 257
G +L ++ +G I L A +++ + +L +K+++YL A++
Sbjct: 729 ---GGELLYYKSPSDVIRKPQGHIELSASCSILRGDN--KQTVQLTT-EKHTYYLTADSP 782
Query: 258 QEMEEWLITLKKIIQI---NTDSLVQEKKETVE 287
+EEW+ L+ ++++ N SL E K T++
Sbjct: 783 NILEEWIKVLQNVLRVQAANPLSLQPEGKPTMK 815
>gi|83716021 GRB2-associated binding protein family, member 4 [Homo
sapiens]
Length = 574
Score = 37.7 bits (86), Expect = 0.12
Identities = 31/120 (25%), Positives = 61/120 (50%), Gaps = 14/120 (11%)
Query: 161 SQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLT--QLPDGSYILNSYKDEKNSKESK 218
++ G V+ GWL K+ + + +++R+F L Q +L YK++ SK+
Sbjct: 35 TRSGHVLYSGWLRKSPPEKKLRLF--AWRKRWFILRRGQTSSDPDVLEYYKND-GSKKPL 91
Query: 219 GCIYLDAC----IDVV----QCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKI 270
I L+ C +DV + + + F++K ++ + YL AET ++M EW+ ++ +I
Sbjct: 92 RTINLNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSER-TFYLVAETREDMNEWVQSICQI 150
>gi|46370073 GRB2-associated binding protein 1 isoform b [Homo
sapiens]
Length = 694
Score = 37.0 bits (84), Expect = 0.20
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 164 GGVIKQGWLHKANVNSTITVTMKVFKRRYFYLT--QLPDGSYILNSYKDEKNSK-----E 216
G V+ GWL K+ + +KRR+F L +L +L YK++ K +
Sbjct: 4 GEVVCSGWLRKSPPEKKLK--RYAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIID 61
Query: 217 SKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQIN 274
C +DA + + + F++ +D+ YL A++E+EM +W+ + I N
Sbjct: 62 LNLCQQVDAGLTFNKKEFENSYIFDINTIDRI-FYLVADSEEEMNKWVRCICDICGFN 118
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,116,922
Number of Sequences: 37866
Number of extensions: 3341815
Number of successful extensions: 8514
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 8282
Number of HSP's gapped (non-prelim): 183
length of query: 2073
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1955
effective length of database: 13,779,330
effective search space: 26938590150
effective search space used: 26938590150
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.