Search of human proteins with 109452591

Search of human proteins with 109452591

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109452591 succinate-CoA ligase, GDP-forming alpha subunit
[Homo sapiens]
         (346 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109452591 succinate-CoA ligase, GDP-forming alpha subunit [Ho...   690   0.0  
gi|38569423 ATP citrate lyase isoform 2 [Homo sapiens]                 87   3e-17
gi|38569421 ATP citrate lyase isoform 1 [Homo sapiens]                 87   3e-17
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]     36   0.044
gi|11342678 amyloid beta (A4) precursor protein-binding, family ...    35   0.076
gi|156071452 nardilysin isoform b [Homo sapiens]                       30   4.1  

>gi|109452591 succinate-CoA ligase, GDP-forming alpha subunit [Homo
           sapiens]
          Length = 346

 Score =  690 bits (1780), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MTATLAAAADIATMVSGSSGLAAARLLSRSFLLPQNGIRHCSYTASRQHLYVDKNTKIIC 60
           MTATLAAAADIATMVSGSSGLAAARLLSRSFLLPQNGIRHCSYTASRQHLYVDKNTKIIC
Sbjct: 1   MTATLAAAADIATMVSGSSGLAAARLLSRSFLLPQNGIRHCSYTASRQHLYVDKNTKIIC 60

Query: 61  QGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGQTHLGLPVFNTVKEAKEQTGATASVIYV 120
           QGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGQTHLGLPVFNTVKEAKEQTGATASVIYV
Sbjct: 61  QGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGQTHLGLPVFNTVKEAKEQTGATASVIYV 120

Query: 121 PPPFAAAAINEAIEAEIPLVVCITEGIPQQDMVRVKHKLLRQEKTRLIGPNCPGVINPGE 180
           PPPFAAAAINEAIEAEIPLVVCITEGIPQQDMVRVKHKLLRQEKTRLIGPNCPGVINPGE
Sbjct: 121 PPPFAAAAINEAIEAEIPLVVCITEGIPQQDMVRVKHKLLRQEKTRLIGPNCPGVINPGE 180

Query: 181 CKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFIDCL 240
           CKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFIDCL
Sbjct: 181 CKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFIDCL 240

Query: 241 EIFLNDSATEGIILIGEIGGNAEENAAEFLKQHNSGPNSKPVVSFIAGLTAPPGRRMGHA 300
           EIFLNDSATEGIILIGEIGGNAEENAAEFLKQHNSGPNSKPVVSFIAGLTAPPGRRMGHA
Sbjct: 241 EIFLNDSATEGIILIGEIGGNAEENAAEFLKQHNSGPNSKPVVSFIAGLTAPPGRRMGHA 300

Query: 301 GAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYKEFEKRKML 346
           GAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYKEFEKRKML
Sbjct: 301 GAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYKEFEKRKML 346


>gi|38569423 ATP citrate lyase isoform 2 [Homo sapiens]
          Length = 1091

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 79/267 (29%), Positives = 124/267 (46%), Gaps = 25/267 (9%)

Query: 92  GQTHLGLPVFNTVKEAKEQTGATASVIYVPPPFAA--AAINEAIE----AEIPLVVCITE 145
           G   + +PVF  + +A  +      +I     FA+  +A +  +E    A+I  +  I E
Sbjct: 534 GHKEILIPVFKNMADAMRKHPEVDVLIN----FASLRSAYDSTMETMNYAQIRTIAIIAE 589

Query: 146 GIPQQDMVRVKHKLLRQEKTRLIGPNCPGVINPGECKIG--------IMPGHIHKKGRIG 197
           GIP+  + R   K   Q+   +IGP   G I PG  KIG        I+   +++ G + 
Sbjct: 590 GIPEA-LTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVA 648

Query: 198 IVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFIDCLEIFLNDSATEGIILIGE 257
            VSRSG ++ E  +  ++   G    V IGGD + G+ F+D +  + +    + I+++GE
Sbjct: 649 YVSRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGE 708

Query: 258 IGGNAEENAAEFLKQHNSGPNSKPVVSFIAGLTA---PPGRRMGHAGAIIAGGKGGAKEK 314
           IGG  E      +K+   G  +KP+V +  G  A       + GHAGA        A  K
Sbjct: 709 IGGTEEYKICRGIKE---GRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAK 765

Query: 315 ISALQSAGVVVSMSPAQLGTTIYKEFE 341
             AL+ AGV V  S  +LG  I   +E
Sbjct: 766 NQALKEAGVFVPRSFDELGEIIQSVYE 792


>gi|38569421 ATP citrate lyase isoform 1 [Homo sapiens]
          Length = 1101

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 79/267 (29%), Positives = 124/267 (46%), Gaps = 25/267 (9%)

Query: 92  GQTHLGLPVFNTVKEAKEQTGATASVIYVPPPFAA--AAINEAIE----AEIPLVVCITE 145
           G   + +PVF  + +A  +      +I     FA+  +A +  +E    A+I  +  I E
Sbjct: 544 GHKEILIPVFKNMADAMRKHPEVDVLIN----FASLRSAYDSTMETMNYAQIRTIAIIAE 599

Query: 146 GIPQQDMVRVKHKLLRQEKTRLIGPNCPGVINPGECKIG--------IMPGHIHKKGRIG 197
           GIP+  + R   K   Q+   +IGP   G I PG  KIG        I+   +++ G + 
Sbjct: 600 GIPEA-LTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVA 658

Query: 198 IVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDFIDCLEIFLNDSATEGIILIGE 257
            VSRSG ++ E  +  ++   G    V IGGD + G+ F+D +  + +    + I+++GE
Sbjct: 659 YVSRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGE 718

Query: 258 IGGNAEENAAEFLKQHNSGPNSKPVVSFIAGLTA---PPGRRMGHAGAIIAGGKGGAKEK 314
           IGG  E      +K+   G  +KP+V +  G  A       + GHAGA        A  K
Sbjct: 719 IGGTEEYKICRGIKE---GRLTKPIVCWCIGTCATMFSSEVQFGHAGACANQASETAVAK 775

Query: 315 ISALQSAGVVVSMSPAQLGTTIYKEFE 341
             AL+ AGV V  S  +LG  I   +E
Sbjct: 776 NQALKEAGVFVPRSFDELGEIIQSVYE 802


>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
          Length = 1712

 Score = 36.2 bits (82), Expect = 0.044
 Identities = 46/146 (31%), Positives = 59/146 (40%), Gaps = 23/146 (15%)

Query: 170  PNCPGVINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVG-LGQSLCV---- 224
            P  PGV  P    I   PG I  +G  G   R+G   Y  +  T   G +G ++ +    
Sbjct: 1048 PGFPGVAGPPG--ITGFPGFIGSRGDKGAPGRAGL--YGEIGATGDFGDIGDTINLPGRP 1103

Query: 225  GIGGDPFNGTDFIDCLEIFLNDSATEGIILIGEIGGNAEENAAEFLKQHNSGPNSKPVVS 284
            G+ G+   GT  I  L+ F  +  TEG I    I G         LK     P       
Sbjct: 1104 GLKGE--RGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFP------- 1154

Query: 285  FIAGLTAPPGRRMGHAGAI-IAGGKG 309
               GLT PPG + G  G I + GGKG
Sbjct: 1155 ---GLTGPPGSQ-GELGRIGLPGGKG 1176


>gi|11342678 amyloid beta (A4) precursor protein-binding, family A,
           member 3 [Homo sapiens]
          Length = 575

 Score = 35.4 bits (80), Expect = 0.076
 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 14/102 (13%)

Query: 71  HSQQALEYGTKLVGGTTPGKGGQTHLGLPVFN---TVKEAKEQTGATASVIYVPPPFAAA 127
           H   A   G   +G       G + +GLP+      V+E K QT  T S+++ PP     
Sbjct: 428 HGGPAERSGALSIGDRLTAINGTSLVGLPLAACQAAVRETKSQTSVTLSIVHCPP--VTT 485

Query: 128 AINEAIEAEIPLVVCITE---------GIPQQDMVRVKHKLL 160
           AI     A   L  C+ +         GI ++  +RV H+++
Sbjct: 486 AIIHRPHAREQLGFCVEDGIICSLLRGGIAERGGIRVGHRII 527


>gi|156071452 nardilysin isoform b [Homo sapiens]
          Length = 1151

 Score = 29.6 bits (65), Expect = 4.1
 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 7/72 (9%)

Query: 208 EAVHQTTQVGLGQSLCVGIGGDPFNGTDFIDCLEIFLNDSATEGIILIGEIGGNAEENAA 267
           EA  +TT+     +LCVG+G   F   D +  L  FL     E ++ +G +    E    
Sbjct: 201 EARKKTTEKQSAAALCVGVGS--FADPDDLPGLAHFL-----EHMVFMGSLKYPDENGFD 253

Query: 268 EFLKQHNSGPNS 279
            FLK+H    N+
Sbjct: 254 AFLKKHGGSDNA 265


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,874,292
Number of Sequences: 37866
Number of extensions: 656628
Number of successful extensions: 1478
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1469
Number of HSP's gapped (non-prelim): 8
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.