Guide to the Human Genome
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Search of human proteins with 9966849

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9966849 TP53-induced glycolysis and apoptosis regulator
[Homo sapiens]
         (270 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9966849 TP53-induced glycolysis and apoptosis regulator [Homo...   538   e-153
gi|50593010 bisphosphoglycerate mutase 2 [Homo sapiens]                42   6e-04
gi|4502445 bisphosphoglycerate mutase [Homo sapiens]                   41   0.001
gi|40353764 bisphosphoglycerate mutase [Homo sapiens]                  41   0.001
gi|4505753 bisphosphoglycerate mutase 1 [Homo sapiens]                 39   0.006
gi|71274132 bisphosphoglycerate mutase 4 [Homo sapiens]                33   0.34 
gi|49640014 ubiquitin associated and SH3 domain containing, A sh...    31   1.3  
gi|9507221 ubiquitin associated and SH3 domain containing, A lon...    31   1.3  
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform...    30   2.9  
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform...    30   2.9  

>gi|9966849 TP53-induced glycolysis and apoptosis regulator [Homo
           sapiens]
          Length = 270

 Score =  538 bits (1387), Expect = e-153
 Identities = 270/270 (100%), Positives = 270/270 (100%)

Query: 1   MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLM 60
           MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLM
Sbjct: 1   MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLM 60

Query: 61  RTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPP 120
           RTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPP
Sbjct: 61  RTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPP 120

Query: 121 GGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKV 180
           GGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKV
Sbjct: 121 GGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKV 180

Query: 181 NSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFII 240
           NSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFII
Sbjct: 181 NSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFII 240

Query: 241 NFEEGREVKPTVQCICMNLQDHLNGLTETR 270
           NFEEGREVKPTVQCICMNLQDHLNGLTETR
Sbjct: 241 NFEEGREVKPTVQCICMNLQDHLNGLTETR 270


>gi|50593010 bisphosphoglycerate mutase 2 [Homo sapiens]
          Length = 253

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 37/119 (31%), Positives = 58/119 (48%), Gaps = 6/119 (5%)

Query: 1   MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVK--FTHAFSSD 58
           MA   L +VRHGE+ +N+E    G   D  LSE G ++A      + + K  F   ++S 
Sbjct: 1   MATHRLVMVRHGESTWNQENRFCG-WFDAELSEKGTEEAKRGAKAIKDAKMEFDICYTSV 59

Query: 59  LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF 117
           L R  +T+  IL+ +     + V    RL ER YG + G  L++    AK   E+  ++
Sbjct: 60  LKRAIRTLWAILDGTDQMW-LPVVRTWRLNERHYGGLTG--LNKAETAAKHGEEQVKIW 115


>gi|4502445 bisphosphoglycerate mutase [Homo sapiens]
          Length = 259

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 9/127 (7%)

Query: 1   MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSD 58
           M+++ L ++RHGE  +NKE       VD+ L+  G ++A   G  L   N +F   F+S 
Sbjct: 1   MSKYKLIMLRHGEGAWNKENRF-CSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSV 59

Query: 59  LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVV-----EGKALSELRAMAKAAREE 113
           L R+  T   ILE     + + V+   RL ER YG +     E  AL+      +  R  
Sbjct: 60  LNRSIHTAWLILEELG-QEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRS 118

Query: 114 CPVFTPP 120
             V  PP
Sbjct: 119 YNVTPPP 125


>gi|40353764 bisphosphoglycerate mutase [Homo sapiens]
          Length = 259

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 9/127 (7%)

Query: 1   MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSD 58
           M+++ L ++RHGE  +NKE       VD+ L+  G ++A   G  L   N +F   F+S 
Sbjct: 1   MSKYKLIMLRHGEGAWNKENRF-CSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSV 59

Query: 59  LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVV-----EGKALSELRAMAKAAREE 113
           L R+  T   ILE     + + V+   RL ER YG +     E  AL+      +  R  
Sbjct: 60  LNRSIHTAWLILEELG-QEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRS 118

Query: 114 CPVFTPP 120
             V  PP
Sbjct: 119 YNVTPPP 125


>gi|4505753 bisphosphoglycerate mutase 1 [Homo sapiens]
          Length = 254

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 38/127 (29%), Positives = 55/127 (43%), Gaps = 9/127 (7%)

Query: 1   MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNV--KFTHAFSSD 58
           MA + L ++RHGE+ +N E    G   D  LS  G ++A   G  L +   +F   F+S 
Sbjct: 1   MAAYKLVLIRHGESAWNLENRFSG-WYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSV 59

Query: 59  LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSEL-----RAMAKAAREE 113
             R  +T+  +L+       + V    RL ER YG + G   +E       A  K  R  
Sbjct: 60  QKRAIRTLWTVLDAIDQMW-LPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRS 118

Query: 114 CPVFTPP 120
             V  PP
Sbjct: 119 YDVPPPP 125


>gi|71274132 bisphosphoglycerate mutase 4 [Homo sapiens]
          Length = 254

 Score = 32.7 bits (73), Expect = 0.34
 Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 9/127 (7%)

Query: 1   MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNV--KFTHAFSSD 58
           MA + L ++RHGE+ +N E        D  LS  G ++A   G  L +   +F    +S 
Sbjct: 1   MAAYKLVLIRHGESTWNLENRF-SCWYDADLSPAGHEEAKRGGQALRDAGYEFDICLTSV 59

Query: 59  LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSEL-----RAMAKAAREE 113
             R  +T+  +L+       + V    RL ER YG + G   +E       A  K  R  
Sbjct: 60  QKRVIRTLWTVLDAIDQMW-LPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRS 118

Query: 114 CPVFTPP 120
             V  PP
Sbjct: 119 YDVPPPP 125


>gi|49640014 ubiquitin associated and SH3 domain containing, A short
           form [Homo sapiens]
          Length = 623

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 2/64 (3%)

Query: 28  DEPLSETGFKQAAAAGIFL--NNVKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYDS 85
           D PLS  G  Q+  AG  L  + ++ +  F+S  +R  QT   ILE  K  K + ++ + 
Sbjct: 412 DPPLSSCGIFQSRIAGDALLDSGIRISSVFASPALRCVQTAKLILEELKLEKKIKIRVEP 471

Query: 86  RLRE 89
            + E
Sbjct: 472 GIFE 475


>gi|9507221 ubiquitin associated and SH3 domain containing, A long
           form [Homo sapiens]
          Length = 661

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 2/64 (3%)

Query: 28  DEPLSETGFKQAAAAGIFL--NNVKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYDS 85
           D PLS  G  Q+  AG  L  + ++ +  F+S  +R  QT   ILE  K  K + ++ + 
Sbjct: 450 DPPLSSCGIFQSRIAGDALLDSGIRISSVFASPALRCVQTAKLILEELKLEKKIKIRVEP 509

Query: 86  RLRE 89
            + E
Sbjct: 510 GIFE 513


>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
           [Homo sapiens]
          Length = 1814

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 4/75 (5%)

Query: 112 EECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEAD----QKEQFSQGSPSNCLETSLA 167
           E+C    PPG +T+   + +    +E L Q++ KE D      +   +    N L+  L 
Sbjct: 526 EKCSSQQPPGSKTIFSKEKKQSSDYEELIQVLKKEQDIYTHLVKSLQESDSINNLQAELN 585

Query: 168 EIFPLGKNHSSKVNS 182
           +IF L K     V S
Sbjct: 586 KIFALRKQLEQDVLS 600


>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
           [Homo sapiens]
          Length = 1893

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 4/75 (5%)

Query: 112 EECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEAD----QKEQFSQGSPSNCLETSLA 167
           E+C    PPG +T+   + +    +E L Q++ KE D      +   +    N L+  L 
Sbjct: 526 EKCSSQQPPGSKTIFSKEKKQSSDYEELIQVLKKEQDIYTHLVKSLQESDSINNLQAELN 585

Query: 168 EIFPLGKNHSSKVNS 182
           +IF L K     V S
Sbjct: 586 KIFALRKQLEQDVLS 600


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,657,759
Number of Sequences: 37866
Number of extensions: 393090
Number of successful extensions: 892
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 891
Number of HSP's gapped (non-prelim): 10
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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