Guide to the Human Genome
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Search of human proteins with 9966764

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9966764 lysophospholipase II [Homo sapiens]
         (231 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9966764 lysophospholipase II [Homo sapiens]                        472   e-133
gi|5453722 lysophospholipase 1 [Homo sapiens]                         329   1e-90
gi|20270341 lysophospholipase-like 1 [Homo sapiens]                   104   6e-23
gi|51242953 monoglyceride lipase isoform 2 [Homo sapiens]              33   0.21 
gi|6005786 monoglyceride lipase isoform 1 [Homo sapiens]               33   0.21 
gi|62420888 dipeptidyl peptidase 7 preproprotein [Homo sapiens]        29   3.0  
gi|32528310 abhydrolase domain containing 12B isoform c [Homo sa...    29   3.0  
gi|32451492 abhydrolase domain containing 12B isoform b [Homo sa...    29   3.0  
gi|170763479 MMS19 nucleotide excision repair homolog [Homo sapi...    29   3.9  
gi|109689718 abhydrolase domain containing 12 isoform a [Homo sa...    28   5.1  
gi|88853865 isoamyl acetate-hydrolyzing esterase 1 homolog [Homo...    28   5.1  

>gi|9966764 lysophospholipase II [Homo sapiens]
          Length = 231

 Score =  472 bits (1214), Expect = e-133
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 1   MCGNTMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAP 60
           MCGNTMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAP
Sbjct: 1   MCGNTMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAP 60

Query: 61  RIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGG 120
           RIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGG
Sbjct: 61  RIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGG 120

Query: 121 FSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAILQCHGELDPMVP 180
           FSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAILQCHGELDPMVP
Sbjct: 121 FSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAILQCHGELDPMVP 180

Query: 181 VRFGALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLLPPV 231
           VRFGALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLLPPV
Sbjct: 181 VRFGALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLLPPV 231


>gi|5453722 lysophospholipase 1 [Homo sapiens]
          Length = 230

 Score =  329 bits (843), Expect = 1e-90
 Identities = 157/232 (67%), Positives = 188/232 (81%), Gaps = 4/232 (1%)

Query: 1   MCGNTMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAP 60
           MCGN MS PL    A V  A + TAAVIFLHGLGDTGH WA+A + IR  H+KYICPHAP
Sbjct: 1   MCGNNMSTPL---PAIVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSSHIKYICPHAP 57

Query: 61  RIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGG 120
             PVTLNM + MPSWFD++GLSPD+ EDE+GIK+AAENIKALI+ E+KNGIP+NRI+LGG
Sbjct: 58  VRPVTLNMNVAMPSWFDIIGLSPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGG 117

Query: 121 FSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSA-KDLAILQCHGELDPMV 179
           FSQGGALSLYTALT    LAG+ ALSCWLPL  +FPQ   G A +D++ILQCHG+ DP+V
Sbjct: 118 FSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFPQGPIGGANRDISILQCHGDCDPLV 177

Query: 180 PVRFGALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLLPPV 231
           P+ FG+LT EKL+++V PA V FKTY G+MHSSC QEM  VK+F++KLLPP+
Sbjct: 178 PLMFGSLTVEKLKTLVNPANVTFKTYEGMMHSSCQQEMMDVKQFIDKLLPPI 229


>gi|20270341 lysophospholipase-like 1 [Homo sapiens]
          Length = 237

 Score =  104 bits (260), Expect = 6e-23
 Identities = 73/221 (33%), Positives = 110/221 (49%), Gaps = 12/221 (5%)

Query: 17  VSGAERETAAVIFLHGLGDTGHS---WADAL--STIRLPHVKYICPHAPRIPVTLNMKMV 71
           VS A R +A++IFLHG GD+G     W   +    +   H+K I P AP    T     +
Sbjct: 14  VSPAGRHSASLIFLHGSGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGI 73

Query: 72  MPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYT 131
              WFD   ++ D PE    I    + +  LI+ E+K+GI  NRI++GGFS GG ++++ 
Sbjct: 74  SNVWFDRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRILIGGFSMGGCMAMHL 133

Query: 132 ALTCPHPLAGIVALSCWLPLHRAFPQA---ANGSAKDLAILQCHGELDPMVPVRFGALTA 188
           A      +AG+ ALS +L    A  QA   +NG   +L   QCHG  D +V   +   T 
Sbjct: 134 AYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPEL--FQCHGTADELVLHSWAEETN 191

Query: 189 EKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLLP 229
             L+S+      +F ++P V H     E+  +K ++   LP
Sbjct: 192 SMLKSL--GVTTKFHSFPNVYHELSKTELDILKLWILTKLP 230


>gi|51242953 monoglyceride lipase isoform 2 [Homo sapiens]
          Length = 303

 Score = 33.1 bits (74), Expect = 0.21
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 5/63 (7%)

Query: 99  IKALIEH--EMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFP 156
           ++ +++H   M+   P   + L G S GGA+++ TA   P   AG+V +S   PL  A P
Sbjct: 97  VRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLIS---PLVLANP 153

Query: 157 QAA 159
           ++A
Sbjct: 154 ESA 156


>gi|6005786 monoglyceride lipase isoform 1 [Homo sapiens]
          Length = 313

 Score = 33.1 bits (74), Expect = 0.21
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 5/63 (7%)

Query: 99  IKALIEH--EMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFP 156
           ++ +++H   M+   P   + L G S GGA+++ TA   P   AG+V +S   PL  A P
Sbjct: 107 VRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLIS---PLVLANP 163

Query: 157 QAA 159
           ++A
Sbjct: 164 ESA 166


>gi|62420888 dipeptidyl peptidase 7 preproprotein [Homo sapiens]
          Length = 492

 Score = 29.3 bits (64), Expect = 3.0
 Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 3/58 (5%)

Query: 89  EAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALS 146
           E  +   AE ++AL         PA  I  GG S GG LS Y  +  PH +AG +A S
Sbjct: 132 EQALADFAELLRALRRDLGAQDAPA--IAFGG-SYGGMLSAYLRMKYPHLVAGALAAS 186


>gi|32528310 abhydrolase domain containing 12B isoform c [Homo
           sapiens]
          Length = 285

 Score = 29.3 bits (64), Expect = 3.0
 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 5/77 (6%)

Query: 155 FPQAANGSAKDLAILQCHGELDPMVPVRFGALTAEKLRSVV-TPARVQFKTY-PGVMHS- 211
           FP   N       +L  HGE D  VP+ +G    E  R+      RV+   + PG  H+ 
Sbjct: 206 FPNDENVKFLSSPLLILHGEDDRTVPLEYGKKLYEIARNAYRNKERVKMVIFPPGFQHNL 265

Query: 212 --SCPQEMAAVKEFLEK 226
               P  +  V++FL K
Sbjct: 266 LCKSPTLLITVRDFLSK 282


>gi|32451492 abhydrolase domain containing 12B isoform b [Homo
           sapiens]
          Length = 255

 Score = 29.3 bits (64), Expect = 3.0
 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 5/77 (6%)

Query: 155 FPQAANGSAKDLAILQCHGELDPMVPVRFGALTAEKLRSVV-TPARVQFKTY-PGVMHS- 211
           FP   N       +L  HGE D  VP+ +G    E  R+      RV+   + PG  H+ 
Sbjct: 176 FPNDENVKFLSSPLLILHGEDDRTVPLEYGKKLYEIARNAYRNKERVKMVIFPPGFQHNL 235

Query: 212 --SCPQEMAAVKEFLEK 226
               P  +  V++FL K
Sbjct: 236 LCKSPTLLITVRDFLSK 252


>gi|170763479 MMS19 nucleotide excision repair homolog [Homo
           sapiens]
          Length = 1030

 Score = 28.9 bits (63), Expect = 3.9
 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 1/76 (1%)

Query: 129 LYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAILQCHGELDPMVPVRFGALTA 188
           L  AL+CP  +  +  LSC  PL    PQ  +     L     +    P + VR  AL  
Sbjct: 918 LLEALSCPDCVVQLSTLSCLQPLLLEAPQVMSLHVDTLVTKFLNLSSSPSMAVRIAALQC 977

Query: 189 -EKLRSVVTPARVQFK 203
              L  + TP  + +K
Sbjct: 978 MHALTRLPTPVLLPYK 993


>gi|109689718 abhydrolase domain containing 12 isoform a [Homo
           sapiens]
          Length = 398

 Score = 28.5 bits (62), Expect = 5.1
 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 16/74 (21%)

Query: 168 ILQCHGELDPMVPVRFGALTAEKLRSVVTPAR---------VQFKTYPGVMHS---SCPQ 215
           +L  H E DP+VP + G     KL S+  PAR         V F +  G  H      P+
Sbjct: 325 LLILHAEDDPVVPFQLG----RKLYSIAAPARSFRDFKVQFVPFHSDLGYRHKYIYKSPE 380

Query: 216 EMAAVKEFLEKLLP 229
               ++EFL K  P
Sbjct: 381 LPRILREFLGKSEP 394


>gi|88853865 isoamyl acetate-hydrolyzing esterase 1 homolog [Homo
           sapiens]
          Length = 248

 Score = 28.5 bits (62), Expect = 5.1
 Identities = 16/68 (23%), Positives = 35/68 (51%), Gaps = 2/68 (2%)

Query: 53  KYICPHAPRIPVTLNMKMVMPSWFDL--MGLSPDAPEDEAGIKKAAENIKALIEHEMKNG 110
           K I P   R   +L++ + +  +F      L  + P+    +++ A N+K+++++     
Sbjct: 63  KIILPRLIRKGNSLDIPVAVTIFFGANDSALKDENPKQHIPLEEYAANLKSMVQYLKSVD 122

Query: 111 IPANRIVL 118
           IP NR++L
Sbjct: 123 IPENRVIL 130


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,017,739
Number of Sequences: 37866
Number of extensions: 377816
Number of successful extensions: 748
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 738
Number of HSP's gapped (non-prelim): 12
length of query: 231
length of database: 18,247,518
effective HSP length: 99
effective length of query: 132
effective length of database: 14,498,784
effective search space: 1913839488
effective search space used: 1913839488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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