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Search of human proteins with 8923911
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923911 LanC lantibiotic synthetase component C-like 2 [Homo
sapiens]
(450 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923911 LanC lantibiotic synthetase component C-like 2 [Homo ... 930 0.0
gi|5174445 lanthionine synthetase C-like protein 1 [Homo sapiens] 483 e-136
gi|212274477 lanthionine synthetase C-like protein 1 [Homo sapiens] 483 e-136
gi|212274337 lanthionine synthetase C-like protein 1 [Homo sapiens] 483 e-136
gi|38348330 LanC lantibiotic synthetase component C-like 3 [Homo... 184 2e-46
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 32 1.5
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 32 1.5
gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Hom... 32 1.5
gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Hom... 32 1.5
gi|37588853 vasoactive intestinal peptide isoform 2 preproprotei... 30 4.5
gi|58532587 BTB (POZ) domain containing 7 isoform 1 [Homo sapiens] 29 9.9
>gi|8923911 LanC lantibiotic synthetase component C-like 2 [Homo
sapiens]
Length = 450
Score = 930 bits (2403), Expect = 0.0
Identities = 450/450 (100%), Positives = 450/450 (100%)
Query: 1 MGETMSKRLKLHLGGEAEMEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPG 60
MGETMSKRLKLHLGGEAEMEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPG
Sbjct: 1 MGETMSKRLKLHLGGEAEMEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPG 60
Query: 61 LPFHQDGKIIHNFIRRIQTKIKDLLQQMEEGLKTADPHDCSAYTGWTGIALLYLQLYRVT 120
LPFHQDGKIIHNFIRRIQTKIKDLLQQMEEGLKTADPHDCSAYTGWTGIALLYLQLYRVT
Sbjct: 61 LPFHQDGKIIHNFIRRIQTKIKDLLQQMEEGLKTADPHDCSAYTGWTGIALLYLQLYRVT 120
Query: 121 CDQTYLLRSLDYVKRTLRNLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQ 180
CDQTYLLRSLDYVKRTLRNLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQ
Sbjct: 121 CDQTYLLRSLDYVKRTLRNLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQ 180
Query: 181 LQRSVVCQESDLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSR 240
LQRSVVCQESDLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSR
Sbjct: 181 LQRSVVCQESDLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSR 240
Query: 241 EERKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKK 300
EERKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKK
Sbjct: 241 EERKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKK 300
Query: 301 FRSGNYPSSLSNETDRLVHWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLL 360
FRSGNYPSSLSNETDRLVHWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLL
Sbjct: 301 FRSGNYPSSLSNETDRLVHWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLL 360
Query: 361 RKGYGICHGTAGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSLFEG 420
RKGYGICHGTAGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSLFEG
Sbjct: 361 RKGYGICHGTAGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSLFEG 420
Query: 421 MAGAIHFLSDVLGPETSRFPAFELDSSKRD 450
MAGAIHFLSDVLGPETSRFPAFELDSSKRD
Sbjct: 421 MAGAIHFLSDVLGPETSRFPAFELDSSKRD 450
>gi|5174445 lanthionine synthetase C-like protein 1 [Homo sapiens]
Length = 399
Score = 483 bits (1244), Expect = e-136
Identities = 231/426 (54%), Positives = 304/426 (71%), Gaps = 27/426 (6%)
Query: 19 MEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPGLPFHQDGKIIHNFIRRIQ 78
M +RAF NP+ DY + LA G + G + P F +R+
Sbjct: 1 MAQRAFPNPYADYNKS----LAEGYFDAAGRLTP-------------------EFSQRLT 37
Query: 79 TKIKDLLQQMEEGLKTADPHDCSAYTGWTGIALLYLQLYRVTCDQTYLLRSLDYVKRTLR 138
KI++LLQQME GLK+ADP D + YTGW GIA+LYL LY V D YL + YVK++L
Sbjct: 38 NKIRELLQQMERGLKSADPRDGTGYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLN 97
Query: 139 NLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQESDLPDELLY 198
L R +TFLCGDAGPLAV AV+YHK+ ++ ++++C+T+L+ L + + P+E+LY
Sbjct: 98 CLTKRSITFLCGDAGPLAVAAVLYHKMNNEKQAEDCITRLIHLNKI----DPHAPNEMLY 153
Query: 199 GRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSREERKTERCPLLYQWHRKQ 258
GR GY+YALL++N G + +S I+++ I+ SG+ L+R+ T + PL+Y+W+++
Sbjct: 154 GRIGYIYALLFVNKNFGVEKIPQSHIQQICETILTSGENLARKRNFTAKSPLMYEWYQEY 213
Query: 259 YVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLV 318
YVGAAHG+AGIYY LMQP+ +V Q L +VKPS+DYV KF SGNYP + + D LV
Sbjct: 214 YVGAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLV 273
Query: 319 HWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGTAGNGYSFL 378
HWCHGAPGVI+ML+QAYKVF+EEKYL +A +C+DVIWQ GLL+KGYG+CHG+AGN Y+FL
Sbjct: 274 HWCHGAPGVIYMLIQAYKVFREEKYLCDAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFL 333
Query: 379 SLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSLFEGMAGAIHFLSDVLGPETSR 438
+LY LTQD KYLYRACKFAEWCL+YG HGCR PD P+SLFEGMAG I+FL+D+L P +R
Sbjct: 334 TLYNLTQDMKYLYRACKFAEWCLEYGEHGCRTPDTPFSLFEGMAGTIYFLADLLVPTKAR 393
Query: 439 FPAFEL 444
FPAFEL
Sbjct: 394 FPAFEL 399
>gi|212274477 lanthionine synthetase C-like protein 1 [Homo sapiens]
Length = 399
Score = 483 bits (1244), Expect = e-136
Identities = 231/426 (54%), Positives = 304/426 (71%), Gaps = 27/426 (6%)
Query: 19 MEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPGLPFHQDGKIIHNFIRRIQ 78
M +RAF NP+ DY + LA G + G + P F +R+
Sbjct: 1 MAQRAFPNPYADYNKS----LAEGYFDAAGRLTP-------------------EFSQRLT 37
Query: 79 TKIKDLLQQMEEGLKTADPHDCSAYTGWTGIALLYLQLYRVTCDQTYLLRSLDYVKRTLR 138
KI++LLQQME GLK+ADP D + YTGW GIA+LYL LY V D YL + YVK++L
Sbjct: 38 NKIRELLQQMERGLKSADPRDGTGYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLN 97
Query: 139 NLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQESDLPDELLY 198
L R +TFLCGDAGPLAV AV+YHK+ ++ ++++C+T+L+ L + + P+E+LY
Sbjct: 98 CLTKRSITFLCGDAGPLAVAAVLYHKMNNEKQAEDCITRLIHLNKI----DPHAPNEMLY 153
Query: 199 GRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSREERKTERCPLLYQWHRKQ 258
GR GY+YALL++N G + +S I+++ I+ SG+ L+R+ T + PL+Y+W+++
Sbjct: 154 GRIGYIYALLFVNKNFGVEKIPQSHIQQICETILTSGENLARKRNFTAKSPLMYEWYQEY 213
Query: 259 YVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLV 318
YVGAAHG+AGIYY LMQP+ +V Q L +VKPS+DYV KF SGNYP + + D LV
Sbjct: 214 YVGAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLV 273
Query: 319 HWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGTAGNGYSFL 378
HWCHGAPGVI+ML+QAYKVF+EEKYL +A +C+DVIWQ GLL+KGYG+CHG+AGN Y+FL
Sbjct: 274 HWCHGAPGVIYMLIQAYKVFREEKYLCDAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFL 333
Query: 379 SLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSLFEGMAGAIHFLSDVLGPETSR 438
+LY LTQD KYLYRACKFAEWCL+YG HGCR PD P+SLFEGMAG I+FL+D+L P +R
Sbjct: 334 TLYNLTQDMKYLYRACKFAEWCLEYGEHGCRTPDTPFSLFEGMAGTIYFLADLLVPTKAR 393
Query: 439 FPAFEL 444
FPAFEL
Sbjct: 394 FPAFEL 399
>gi|212274337 lanthionine synthetase C-like protein 1 [Homo sapiens]
Length = 399
Score = 483 bits (1244), Expect = e-136
Identities = 231/426 (54%), Positives = 304/426 (71%), Gaps = 27/426 (6%)
Query: 19 MEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPGLPFHQDGKIIHNFIRRIQ 78
M +RAF NP+ DY + LA G + G + P F +R+
Sbjct: 1 MAQRAFPNPYADYNKS----LAEGYFDAAGRLTP-------------------EFSQRLT 37
Query: 79 TKIKDLLQQMEEGLKTADPHDCSAYTGWTGIALLYLQLYRVTCDQTYLLRSLDYVKRTLR 138
KI++LLQQME GLK+ADP D + YTGW GIA+LYL LY V D YL + YVK++L
Sbjct: 38 NKIRELLQQMERGLKSADPRDGTGYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLN 97
Query: 139 NLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQESDLPDELLY 198
L R +TFLCGDAGPLAV AV+YHK+ ++ ++++C+T+L+ L + + P+E+LY
Sbjct: 98 CLTKRSITFLCGDAGPLAVAAVLYHKMNNEKQAEDCITRLIHLNKI----DPHAPNEMLY 153
Query: 199 GRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSREERKTERCPLLYQWHRKQ 258
GR GY+YALL++N G + +S I+++ I+ SG+ L+R+ T + PL+Y+W+++
Sbjct: 154 GRIGYIYALLFVNKNFGVEKIPQSHIQQICETILTSGENLARKRNFTAKSPLMYEWYQEY 213
Query: 259 YVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLV 318
YVGAAHG+AGIYY LMQP+ +V Q L +VKPS+DYV KF SGNYP + + D LV
Sbjct: 214 YVGAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLV 273
Query: 319 HWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGTAGNGYSFL 378
HWCHGAPGVI+ML+QAYKVF+EEKYL +A +C+DVIWQ GLL+KGYG+CHG+AGN Y+FL
Sbjct: 274 HWCHGAPGVIYMLIQAYKVFREEKYLCDAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFL 333
Query: 379 SLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSLFEGMAGAIHFLSDVLGPETSR 438
+LY LTQD KYLYRACKFAEWCL+YG HGCR PD P+SLFEGMAG I+FL+D+L P +R
Sbjct: 334 TLYNLTQDMKYLYRACKFAEWCLEYGEHGCRTPDTPFSLFEGMAGTIYFLADLLVPTKAR 393
Query: 439 FPAFEL 444
FPAFEL
Sbjct: 394 FPAFEL 399
>gi|38348330 LanC lantibiotic synthetase component C-like 3 [Homo
sapiens]
Length = 388
Score = 184 bits (466), Expect = 2e-46
Identities = 134/392 (34%), Positives = 194/392 (49%), Gaps = 48/392 (12%)
Query: 21 ERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPGLPFHQDGKIIHNFIRRIQTK 80
+R F N F DY+ G+LLA G EE V P T I RI +
Sbjct: 4 KRCFANRFDDYQ---GSLLA-GQCEEA--VAPLVTAT----------------IERILQE 41
Query: 81 IKDLLQQMEEGLKTADPHDCSA--YTGWTGIALLYLQLYRVTCDQTYLLRSLDYVKRTLR 138
+ L E TA C Y G G+A + LY V+ + Y++ R
Sbjct: 42 LPPLGGGAEARGATAGASACQGGLYGGVAGVAYM---LYHVSQSPLFATARERYLRSAKR 98
Query: 139 NLNG-------------RRVTFLCGDAGPLAVGAVIYHKL-RSDCESQECVTKLLQLQRS 184
++ R FL G AG AV ++YH L RSD + L +
Sbjct: 99 LIDACARAEEWGEPDADTRAAFLLGGAGVYAVATLVYHALGRSDYVQPLGKFRALCAVCA 158
Query: 185 VVCQESDLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSREERK 244
V DEL GRAGYL A L L ++ + + IK + AI++SGK + ++RK
Sbjct: 159 PVSFLECGSDELFVGRAGYLCAALVLKQKLAQEVLTPAQIKSICQAILDSGKQYAIKKRK 218
Query: 245 TERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKKFRSG 304
PL+Y ++ +Y+GAAHG++ I ML+ + E+V S+D++ ++ ++
Sbjct: 219 P--FPLMYSYYGTEYLGAAHGLSSILQMLLSYHEHLKPSD-RELVWQSVDFLMEQE-QNC 274
Query: 305 NYPSSLSNETDR---LVHWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLLR 361
N+P L +R LVHWCHGAPG+ ++ +AY V K+ +YL + C ++ WQ+GLL+
Sbjct: 275 NWPPELGETIERENELVHWCHGAPGIAYLFAKAYLVSKKPQYLDTCIRCGELTWQKGLLK 334
Query: 362 KGYGICHGTAGNGYSFLSLYRLTQDKKYLYRA 393
KG GICHG AG+ Y FL LYRLT + KY+YRA
Sbjct: 335 KGPGICHGVAGSAYVFLLLYRLTGNSKYIYRA 366
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23
[Homo sapiens]
Length = 1636
Score = 31.6 bits (70), Expect = 1.5
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 7/66 (10%)
Query: 203 YLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSREERKTERCPLLYQWHRKQYVGA 262
YL L YL + + G+ E+A+ I SGK+++ E+ K E+ +LY +GA
Sbjct: 71 YLGQLHYLQSRVPMGSGQEAAVPVTWTEIF-SGKSVAHEDIKYEQACILYN------LGA 123
Query: 263 AHGMAG 268
H M G
Sbjct: 124 LHSMLG 129
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 31.6 bits (70), Expect = 1.5
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 2/72 (2%)
Query: 25 VNPFPDYEAAAGALLASGAAEETGCVRPPATTD-EPGLPFHQDGKIIHNFIRRIQTKIKD 83
V P PD +++ G LA+ A ++ G P D E H D I + R Q D
Sbjct: 1216 VTPIPDVQSSKGGNLAASAKKKHGSTPPGDNKDVEDSSVIHYDDAAISKLLDRNQDATDD 1275
Query: 84 L-LQQMEEGLKT 94
LQ M E L +
Sbjct: 1276 TELQNMNEYLSS 1287
>gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Homo
sapiens]
Length = 1151
Score = 31.6 bits (70), Expect = 1.5
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 1 MGETMSKRLKLHLGGEAEMEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTD--E 58
+G + L L GGE + + V+P GA+L + TGC+ PPA E
Sbjct: 821 LGTVLVIALNLPPGGEQRLLQPVIVSPSGTILRLKGAILRMAFLDTTGCLIPPAYEPWRE 880
Query: 59 PGLPFHQDGK 68
+P +D K
Sbjct: 881 HNVPEEKDEK 890
>gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Homo
sapiens]
Length = 1115
Score = 31.6 bits (70), Expect = 1.5
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 2/70 (2%)
Query: 1 MGETMSKRLKLHLGGEAEMEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTD--E 58
+G + L L GGE + + V+P GA+L + TGC+ PPA E
Sbjct: 785 LGTVLVIALNLPPGGEQRLLQPVIVSPSGTILRLKGAILRMAFLDTTGCLIPPAYEPWRE 844
Query: 59 PGLPFHQDGK 68
+P +D K
Sbjct: 845 HNVPEEKDEK 854
>gi|37588853 vasoactive intestinal peptide isoform 2 preproprotein
[Homo sapiens]
Length = 169
Score = 30.0 bits (66), Expect = 4.5
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 120 TCDQTYLLRSLDYVKRTLRNLNGRRVTFLCGDAGPL-----AVGAVIYHKLRSDCESQEC 174
T D + LL L K+ L +L G+RV+ + D P+ AV Y +LR ++
Sbjct: 87 TSDFSKLLGQLS-AKKYLESLMGKRVSNISEDPVPVKRHSDAVFTDNYTRLRKQMAVKKY 145
Query: 175 VTKLLQLQRSVVCQESDLPDEL 196
+ +L +RS + D P+EL
Sbjct: 146 LNSILNGKRSSEGESPDFPEEL 167
>gi|58532587 BTB (POZ) domain containing 7 isoform 1 [Homo sapiens]
Length = 1132
Score = 28.9 bits (63), Expect = 9.9
Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 2/58 (3%)
Query: 267 AGIYYM--LMQPAAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLVHWCH 322
AGIY L P + + L EM+ D VR + R N P +L + + CH
Sbjct: 567 AGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVNNAVPQCCH 624
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,789,781
Number of Sequences: 37866
Number of extensions: 790913
Number of successful extensions: 1704
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1670
Number of HSP's gapped (non-prelim): 12
length of query: 450
length of database: 18,247,518
effective HSP length: 106
effective length of query: 344
effective length of database: 14,233,722
effective search space: 4896400368
effective search space used: 4896400368
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.