Search of human proteins with 8922995

Search of human proteins with 8922995

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8922995 phosphatidylinositol-specific phospholipase C, X
domain containing 1 [Homo sapiens]
         (323 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8922995 phosphatidylinositol-specific phospholipase C, X doma...   674   0.0  
gi|197333703 phosphatidylinositol-specific phospholipase C, X do...   176   2e-44
gi|53828920 phosphatidylinositol-specific phospholipase C, X dom...   171   8e-43
gi|23397570 phosphatidylinositol-specific phospholipase C, X dom...   155   5e-38
gi|144446030 lymphocyte antigen 75 [Homo sapiens]                      30   2.2  
gi|32189371 transmembrane protein 165 [Homo sapiens]                   30   2.9  
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]            29   6.5  
gi|194578923 sperm associated antigen 9 isoform 1 [Homo sapiens]       28   8.4  
gi|27436920 sperm associated antigen 9 isoform 3 [Homo sapiens]        28   8.4  
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    28   8.4  
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    28   8.4  
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    28   8.4  

>gi|8922995 phosphatidylinositol-specific phospholipase C, X domain
           containing 1 [Homo sapiens]
          Length = 323

 Score =  674 bits (1740), Expect = 0.0
 Identities = 323/323 (100%), Positives = 323/323 (100%)

Query: 1   MGGQVSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISH 60
           MGGQVSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISH
Sbjct: 1   MGGQVSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISH 60

Query: 61  EESRLLQLLNKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHF 120
           EESRLLQLLNKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHF
Sbjct: 61  EESRLLQLLNKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHF 120

Query: 121 VHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLC 180
           VHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLC
Sbjct: 121 VHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLC 180

Query: 181 PRGEVPTLRQLWSRGQQVIVSYEDESSLRRHHELWPGVPYWWGNRVKTEALIRYLETMKS 240
           PRGEVPTLRQLWSRGQQVIVSYEDESSLRRHHELWPGVPYWWGNRVKTEALIRYLETMKS
Sbjct: 181 PRGEVPTLRQLWSRGQQVIVSYEDESSLRRHHELWPGVPYWWGNRVKTEALIRYLETMKS 240

Query: 241 CGRPGGLFVAGINLTENLQYVLAHPSESLEKMTLPNLPRLSAWVREQCPGPGSRCTNIIA 300
           CGRPGGLFVAGINLTENLQYVLAHPSESLEKMTLPNLPRLSAWVREQCPGPGSRCTNIIA
Sbjct: 241 CGRPGGLFVAGINLTENLQYVLAHPSESLEKMTLPNLPRLSAWVREQCPGPGSRCTNIIA 300

Query: 301 GDFIGADGFVSDVIALNQKLLWC 323
           GDFIGADGFVSDVIALNQKLLWC
Sbjct: 301 GDFIGADGFVSDVIALNQKLLWC 323


>gi|197333703 phosphatidylinositol-specific phospholipase C, X
           domain containing 2 isoform a [Homo sapiens]
          Length = 341

 Score =  176 bits (447), Expect = 2e-44
 Identities = 111/326 (34%), Positives = 178/326 (54%), Gaps = 12/326 (3%)

Query: 1   MGGQVSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISH 60
           MG   S + S ++      N DWM++L P L ++PL +L+IPGSHD+ +Y +++KSP+  
Sbjct: 13  MGTICSPNPSGTKTSSEVCNADWMASLPPHLHNLPLSNLAIPGSHDSFSYWVDEKSPVGP 72

Query: 61  EESRLLQLLNKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHF 120
           ++++ ++ L  A   + + ++ KWSVTQ L   EQL+AG+RY DLR++     +++ ++F
Sbjct: 73  DQTQAIKRL--ARISLVKKLMKKWSVTQNLTFREQLEAGIRYFDLRVSSKPGDADQEIYF 130

Query: 121 VHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLC 180
           +H ++    V D L EI  +L +HP+E++ L   +F  + E  H+ LV  I+  FG+ LC
Sbjct: 131 IHGLFGIK-VWDGLMEIDSFLTQHPQEIIFLDFNHFYAMDETHHKCLVLRIQEAFGNKLC 189

Query: 181 PRGEVP--TLRQLWSRGQQVIVSYEDESSLRRHHELWPG--VPYWWGNRVKTEALIRYLE 236
           P   V   TLR LW +  QV++ Y      +++  LWPG  +P  W N      LI +LE
Sbjct: 190 PACSVESLTLRTLWEKNCQVLIFYHC-PFYKQYPFLWPGKKIPAPWANTTSVRKLILFLE 248

Query: 237 -TMKSCGRPGGLFVAGINLTENLQYVLAHPSESLEK-MTLPNLPRLSAWVREQCPGPGSR 294
            T+      G   V+   LT  ++ +       L+  +   NLP +  WV+ Q   PG+ 
Sbjct: 249 TTLSERASRGSFHVSQAILTPRVKTIARGLVGGLKNTLVHRNLPAILDWVKTQ--KPGAM 306

Query: 295 CTNIIAGDFIGADGFVSDVIALNQKL 320
             NII  DF+    F + VI LN  L
Sbjct: 307 GVNIITSDFVDLVDFAATVIKLNDLL 332


>gi|53828920 phosphatidylinositol-specific phospholipase C, X domain
           containing 3 [Homo sapiens]
          Length = 321

 Score =  171 bits (433), Expect = 8e-43
 Identities = 102/302 (33%), Positives = 164/302 (54%), Gaps = 10/302 (3%)

Query: 22  DWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISHEESRLLQLLNKALPCITRPVV 81
           DWM+ L   +  +PL +L+IPGSHD+ ++ +++ SP+  E+   +Q        + + ++
Sbjct: 14  DWMATLPESMHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVSVFGTVAKKLM 73

Query: 82  LKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHFVHMVYTTALVEDTLTEISEWL 141
            KW  TQ ++ T QL AG+RY DLRI+      +  L+F H ++ +A V + L EI+ +L
Sbjct: 74  RKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLF-SAKVNEGLEEINAFL 132

Query: 142 ERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLCPR--GEVPTLRQLWSRGQQVI 199
             H +EVV L   +F G+ +  HE LV  +K+I+G+ +CP    +  +L+ LW +  QV+
Sbjct: 133 TDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFAQEVSLKYLWEKDYQVL 192

Query: 200 VSYEDESSLRRHHELWPG--VPYWWGNRVKTEALIRYLE-TMKSCGRPGGLFVAGINLTE 256
           V Y    +L     LWPG  +P  W N    E LI++L+ ++    + G  F++ + LT 
Sbjct: 193 VFYHSPVALEVPF-LWPGQMMPAPWANTTDPEKLIQFLQASITERRKKGSFFISQVVLTP 251

Query: 257 NLQYVLAHPSESL-EKMTLPNLPRLSAWVREQCPGPGSRCTNIIAGDFIGADGFVSDVIA 315
               V+   +  L E +T   LP +  WVR Q PG      NI+  DF+    F+S VI 
Sbjct: 252 KASTVVKGVASGLRETITERALPAMMQWVRTQKPGESG--INIVTADFVELGDFISTVIK 309

Query: 316 LN 317
           LN
Sbjct: 310 LN 311


>gi|23397570 phosphatidylinositol-specific phospholipase C, X domain
           containing 2 isoform b [Homo sapiens]
          Length = 304

 Score =  155 bits (392), Expect = 5e-38
 Identities = 88/244 (36%), Positives = 143/244 (58%), Gaps = 8/244 (3%)

Query: 1   MGGQVSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISH 60
           MG   S + S ++      N DWM++L P L ++PL +L+IPGSHD+ +Y +++KSP+  
Sbjct: 13  MGTICSPNPSGTKTSSEVCNADWMASLPPHLHNLPLSNLAIPGSHDSFSYWVDEKSPVGP 72

Query: 61  EESRLLQLLNKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHF 120
           ++++ ++ L  A   + + ++ KWSVTQ L   EQL+AG+RY DLR++     +++ ++F
Sbjct: 73  DQTQAIKRL--ARISLVKKLMKKWSVTQNLTFREQLEAGIRYFDLRVSSKPGDADQEIYF 130

Query: 121 VHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLC 180
           +H ++    V D L EI  +L +HP+E++ L   +F  + E  H+ LV  I+  FG+ LC
Sbjct: 131 IHGLFGIK-VWDGLMEIDSFLTQHPQEIIFLDFNHFYAMDETHHKCLVLRIQEAFGNKLC 189

Query: 181 PRGEVP--TLRQLWSRGQQVIVSYEDESSLRRHHELWPG--VPYWWGNRVKTEALIRYLE 236
           P   V   TLR LW +  QV++ Y      +++  LWPG  +P  W N      LI +LE
Sbjct: 190 PACSVESLTLRTLWEKNCQVLIFYHC-PFYKQYPFLWPGKKIPAPWANTTSVRKLILFLE 248

Query: 237 TMKS 240
           T  S
Sbjct: 249 TTLS 252


>gi|144446030 lymphocyte antigen 75 [Homo sapiens]
          Length = 1722

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 41/140 (29%), Positives = 55/140 (39%), Gaps = 37/140 (26%)

Query: 147 EVVILACRNFEGLSEDLHEYLVACIKNIFGDMLCPRGEVPTLRQLWSRGQQVIVSYEDES 206
           EVV+    N     ED+ E +   +KNI          +PTL Q WS G +V ++Y DE+
Sbjct: 406 EVVVTKLHN-----EDIKEEVWIGLKNI---------NIPTLFQ-WSDGTEVTLTYWDEN 450

Query: 207 SLRRHHELWPGVPYWWGNRVKTEALIRYLETMKSCGRPGGLFVAGINLTENLQYVLAHPS 266
                    P VPY      KT   + YL      G  G   V   +  E L+YV     
Sbjct: 451 E--------PNVPY-----NKTPNCVSYL------GELGQWKVQ--SCEEKLKYVCKRKG 489

Query: 267 ESLEKMTLPNL-PRLSAWVR 285
           E L   +   + P    W R
Sbjct: 490 EKLNDASSDKMCPPDEGWKR 509


>gi|32189371 transmembrane protein 165 [Homo sapiens]
          Length = 324

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 3/40 (7%)

Query: 115 EKNLHFVHMVYTTALVEDTLTEISEWLERHPREVVILACR 154
           +K LHF+  ++  AL   TLT ++EW +R     ++LA R
Sbjct: 227 KKWLHFISPIFVQAL---TLTFLAEWGDRSQLTTIVLAAR 263


>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
          Length = 4265

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 13/53 (24%), Positives = 25/53 (47%)

Query: 104  DLRIAHMLEGSEKNLHFVHMVYTTALVEDTLTEISEWLERHPREVVILACRNF 156
            DL I HM     + +     +Y ++ VED L E+   ++    +++  A R +
Sbjct: 1368 DLEITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAY 1420


>gi|194578923 sperm associated antigen 9 isoform 1 [Homo sapiens]
          Length = 1321

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 20/68 (29%), Positives = 32/68 (47%)

Query: 146 REVVILACRNFEGLSEDLHEYLVACIKNIFGDMLCPRGEVPTLRQLWSRGQQVIVSYEDE 205
           RE   L  R  E + ++L   +VA ++N+       +     L  L    +Q+I  YE E
Sbjct: 33  REFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYERE 92

Query: 206 SSLRRHHE 213
            +LR+H E
Sbjct: 93  KALRKHAE 100


>gi|27436920 sperm associated antigen 9 isoform 3 [Homo sapiens]
          Length = 1307

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 20/68 (29%), Positives = 32/68 (47%)

Query: 146 REVVILACRNFEGLSEDLHEYLVACIKNIFGDMLCPRGEVPTLRQLWSRGQQVIVSYEDE 205
           RE   L  R  E + ++L   +VA ++N+       +     L  L    +Q+I  YE E
Sbjct: 33  REFERLIGRYDEEVVKELMPLVVAVLENLDSVFAQDQEHQVELELLRDDNEQLITQYERE 92

Query: 206 SSLRRHHE 213
            +LR+H E
Sbjct: 93  KALRKHAE 100


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 12/33 (36%), Positives = 20/33 (60%)

Query: 261  VLAHPSESLEKMTLPNLPRLSAWVREQCPGPGS 293
            V +HPS+S+  ++ PN+P L +   +  P  GS
Sbjct: 1486 VQSHPSQSVRSVSSPNVPALESGYTQISPEQGS 1518


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 12/33 (36%), Positives = 20/33 (60%)

Query: 261  VLAHPSESLEKMTLPNLPRLSAWVREQCPGPGS 293
            V +HPS+S+  ++ PN+P L +   +  P  GS
Sbjct: 1486 VQSHPSQSVRSVSSPNVPALESGYTQISPEQGS 1518


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 28.5 bits (62), Expect = 8.4
 Identities = 12/33 (36%), Positives = 20/33 (60%)

Query: 261  VLAHPSESLEKMTLPNLPRLSAWVREQCPGPGS 293
            V +HPS+S+  ++ PN+P L +   +  P  GS
Sbjct: 1486 VQSHPSQSVRSVSSPNVPALESGYTQISPEQGS 1518


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,624,311
Number of Sequences: 37866
Number of extensions: 619915
Number of successful extensions: 1451
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1429
Number of HSP's gapped (non-prelim): 12
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.