Guide to the Human Genome
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Search of human proteins with 7706278

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7706278 serologically defined breast cancer antigen 84
isoform b [Homo sapiens]
         (383 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7706278 serologically defined breast cancer antigen 84 isofor...   785   0.0  
gi|38327615 serologically defined breast cancer antigen 84 isofo...   779   0.0  
gi|50959176 PTX1 protein [Homo sapiens]                               181   1e-45
gi|72534712 endoplasmic reticulum-golgi intermediate compartment...   110   2e-24
gi|98991776 protection of telomeres 1 isoform 1 [Homo sapiens]         33   0.33 
gi|148806925 EGF, latrophilin and seven transmembrane domain con...    31   1.6  
gi|4557365 Bloom syndrome protein [Homo sapiens]                       30   4.8  

>gi|7706278 serologically defined breast cancer antigen 84 isoform b
           [Homo sapiens]
          Length = 383

 Score =  785 bits (2027), Expect = 0.0
 Identities = 383/383 (100%), Positives = 383/383 (100%)

Query: 1   MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYV 60
           MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYV
Sbjct: 1   MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYV 60

Query: 61  DKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAE 120
           DKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAE
Sbjct: 61  DKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAE 120

Query: 121 RHELGKVEVTVFDPDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTIE 180
           RHELGKVEVTVFDPDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTIE
Sbjct: 121 RHELGKVEVTVFDPDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTIE 180

Query: 181 QCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNI 240
           QCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNI
Sbjct: 181 QCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNI 240

Query: 241 NMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQF 300
           NMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQF
Sbjct: 241 NMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQF 300

Query: 301 SVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAG 360
           SVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAG
Sbjct: 301 SVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAG 360

Query: 361 LIDSLIYHSARAIQKKIDLGKTT 383
           LIDSLIYHSARAIQKKIDLGKTT
Sbjct: 361 LIDSLIYHSARAIQKKIDLGKTT 383


>gi|38327615 serologically defined breast cancer antigen 84 isoform
           a [Homo sapiens]
          Length = 388

 Score =  779 bits (2011), Expect = 0.0
 Identities = 383/388 (98%), Positives = 383/388 (98%), Gaps = 5/388 (1%)

Query: 1   MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYV 60
           MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYV
Sbjct: 1   MEALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYV 60

Query: 61  DKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAE 120
           DKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAE
Sbjct: 61  DKSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAE 120

Query: 121 RHELGKVEVTVFDPDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTIE 180
           RHELGKVEVTVFDPDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTIE
Sbjct: 121 RHELGKVEVTVFDPDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTIE 180

Query: 181 QCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHV-----HDLQSF 235
           QCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHV     HDLQSF
Sbjct: 181 QCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHAVEIHDLQSF 240

Query: 236 GLDNINMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVL 295
           GLDNINMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVL
Sbjct: 241 GLDNINMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVL 300

Query: 296 RTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGM 355
           RTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGM
Sbjct: 301 RTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGM 360

Query: 356 FTVAGLIDSLIYHSARAIQKKIDLGKTT 383
           FTVAGLIDSLIYHSARAIQKKIDLGKTT
Sbjct: 361 FTVAGLIDSLIYHSARAIQKKIDLGKTT 388


>gi|50959176 PTX1 protein [Homo sapiens]
          Length = 377

 Score =  181 bits (458), Expect = 1e-45
 Identities = 119/368 (32%), Positives = 179/368 (48%), Gaps = 44/368 (11%)

Query: 2   EALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVD 61
           + L  +K+ DA+PK  E +   +  G TV++++   M LL + E   Y  T +  E  VD
Sbjct: 8   KTLSLVKELDAFPKVPESYVETSASGGTVSLIAFTTMALLTIMEFSVYQDTWMKYEYEVD 67

Query: 62  KSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAER 121
           K    KL+INID+    M C Y+  D +D+A       +  ++                 
Sbjct: 68  KDFSSKLRINIDITVA-MKCQYVGADVLDLAETMVASADGLVY----------------- 109

Query: 122 HELGKVEVTVFD--PDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTI 179
                 E TVFD  P   +  R      +  ++    ++ +DV   ++    AFK+  T 
Sbjct: 110 ------EPTVFDLSPQQKEWQRMLQLIQSRLQEE---HSLQDV--IFKS---AFKSTSTA 155

Query: 180 EQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDN 239
              R +  SQ         C+++G L VNKVAGNFH   GK+      H H       ++
Sbjct: 156 LPPREDDSSQSPN-----ACRIHGHLYVNKVAGNFHITVGKAIPHPRGHAHLAALVNHES 210

Query: 240 INMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVY--MKVDGEVLRT 297
            N +H I HLSFGE  P I+NPLD T   A   + MFQYF+ VVPT     K+  +   T
Sbjct: 211 YNFSHRIDHLSFGELVPAIINPLDGTEKIAIDHNQMFQYFITVVPTKLHTYKISAD---T 267

Query: 298 NQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFT 357
           +QFSVT  E++ N   G  G+ G+F+ Y+LS +MV +TE+H  F  F   +C I+GG+F+
Sbjct: 268 HQFSVTERERIINHAAGSHGVSGIFMKYDLSSLMVTVTEEHMPFWQFFVRLCGIVGGIFS 327

Query: 358 VAGLIDSL 365
             G++  +
Sbjct: 328 TTGMLHGI 335


>gi|72534712 endoplasmic reticulum-golgi intermediate compartment 32
           kDa protein [Homo sapiens]
          Length = 290

 Score =  110 bits (276), Expect = 2e-24
 Identities = 71/199 (35%), Positives = 101/199 (50%), Gaps = 19/199 (9%)

Query: 188 SQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDNINMTHYIQ 247
           S K+      GC+  G   +NKV GNFH +   +  Q              N +MTH I 
Sbjct: 104 SMKIPLNNGAGCRFEGQFSINKVPGNFHVSTHSATAQPQ------------NPDMTHVIH 151

Query: 248 HLSFGE-----DYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSV 302
            LSFG+     +  G  N L   +           Y +K+VPTVY    G+   + Q++V
Sbjct: 152 KLSFGDTLQVQNIHGAFNALGGADRLTSNPLASHDYILKIVPTVYEDKSGKQRYSYQYTV 211

Query: 303 TRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFTVAGLI 362
              E VA    G + +P ++  Y+LSP+ VK TE+ +    F+T +CAIIGG FTVAG++
Sbjct: 212 ANKEYVAYSHTG-RIIPAIWFRYDLSPITVKYTERRQPLYRFITTICAIIGGTFTVAGIL 270

Query: 363 DSLIYHSARAIQKKIDLGK 381
           DS I+ ++ A  KKI LGK
Sbjct: 271 DSCIFTASEA-WKKIQLGK 288



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 36/101 (35%), Positives = 56/101 (55%), Gaps = 3/101 (2%)

Query: 8   KQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYV---DKSR 64
           ++FD Y K  +D    T  GA ++I   L +L LFLSEL  ++TTEV  ELYV   DK  
Sbjct: 6   RRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDS 65

Query: 65  GDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFK 105
           G K+ +++++  P++ C  + +D  D  G  ++    N  K
Sbjct: 66  GGKIDVSLNISLPNLHCELVGLDIQDEMGRHEVGHIDNSMK 106


>gi|98991776 protection of telomeres 1 isoform 1 [Homo sapiens]
          Length = 634

 Score = 33.5 bits (75), Expect = 0.33
 Identities = 22/95 (23%), Positives = 47/95 (49%), Gaps = 4/95 (4%)

Query: 248 HLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVDGEVLRTNQFSVTRHEK 307
           +LS G DY  +V  +D TNV      ++F    + +P +Y   +G+++R ++  +  ++K
Sbjct: 36  YLSKGTDYCSVVTIVDQTNVKL--TCLLFSGNYEALPIIYK--NGDIVRFHRLKIQVYKK 91

Query: 308 VANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFT 342
              G+         F     +P++ + + K+ +FT
Sbjct: 92  ETQGITSSGFASLTFEGTLGAPIIPRTSSKYFNFT 126


>gi|148806925 EGF, latrophilin and seven transmembrane domain
           containing 1 [Homo sapiens]
          Length = 690

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 26/119 (21%), Positives = 45/119 (37%), Gaps = 2/119 (1%)

Query: 232 LQSFGLDNINMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVYMKVD 291
           L+ F  D+ NM H   H++   DY  I         +    ++ F Y+  + P +    +
Sbjct: 255 LKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFVYYKSIGPLLSSSDN 314

Query: 292 GEVLRTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCA 350
             +   N  +    E+V + ++          LYEL    +  T  HR  T     +CA
Sbjct: 315 FLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELE--KITFTLSHRKVTDRYRSLCA 371


>gi|4557365 Bloom syndrome protein [Homo sapiens]
          Length = 1417

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 21/86 (24%), Positives = 35/86 (40%), Gaps = 5/86 (5%)

Query: 118 EAERHELGKVEVTVFDPDSLD----PDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAF 173
           EAE H   KV    FD D  D    P   E    A +   KC +T +D+  + R+     
Sbjct: 277 EAELHSTEKVPCIEFDDDDYDTDFVPPSPEEIISASSSSSKCLSTLKDLDTSDRKEDVLS 336

Query: 174 KNPDTIEQCRREGFSQKMQEQKNEGC 199
            + D + +  +    Q++  + +  C
Sbjct: 337 TSKDLLSKPEKMSM-QELNPETSTDC 361


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,244,562
Number of Sequences: 37866
Number of extensions: 624499
Number of successful extensions: 1234
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1222
Number of HSP's gapped (non-prelim): 10
length of query: 383
length of database: 18,247,518
effective HSP length: 104
effective length of query: 279
effective length of database: 14,309,454
effective search space: 3992337666
effective search space used: 3992337666
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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