Guide to the Human Genome
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Search of human proteins with 7662308

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662308 transmembrane protein 63A [Homo sapiens]
         (807 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662308 transmembrane protein 63A [Homo sapiens]                  1649   0.0  
gi|55769589 transmembrane protein 63B [Homo sapiens]                  923   0.0  
gi|190341095 transmembrane protein 63C [Homo sapiens]                 602   e-172
gi|91208420 bassoon protein [Homo sapiens]                             32   3.1  
gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo...    31   4.0  
gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo...    31   4.0  
gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo s...    31   4.0  

>gi|7662308 transmembrane protein 63A [Homo sapiens]
          Length = 807

 Score = 1649 bits (4270), Expect = 0.0
 Identities = 807/807 (100%), Positives = 807/807 (100%)

Query: 1   MMDSPFLELWQSKAVSIREQLGLGDRPNDSYCYNSAKNSTVLQGVTFGGIPTVLLIDVSC 60
           MMDSPFLELWQSKAVSIREQLGLGDRPNDSYCYNSAKNSTVLQGVTFGGIPTVLLIDVSC
Sbjct: 1   MMDSPFLELWQSKAVSIREQLGLGDRPNDSYCYNSAKNSTVLQGVTFGGIPTVLLIDVSC 60

Query: 61  FLFLILVFSIIRRRFWDYGRIALVSEADSESRFQRLSSTSSSGQQDFENELGCCPWLTAI 120
           FLFLILVFSIIRRRFWDYGRIALVSEADSESRFQRLSSTSSSGQQDFENELGCCPWLTAI
Sbjct: 61  FLFLILVFSIIRRRFWDYGRIALVSEADSESRFQRLSSTSSSGQQDFENELGCCPWLTAI 120

Query: 121 FRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGR 180
           FRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGR
Sbjct: 121 FRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGR 180

Query: 181 TTIANLQTDNDLLWLHTIFAVIYLFFTVGFMRHHTQSIKYKEENLVRRTLFITGLPRDAR 240
           TTIANLQTDNDLLWLHTIFAVIYLFFTVGFMRHHTQSIKYKEENLVRRTLFITGLPRDAR
Sbjct: 181 TTIANLQTDNDLLWLHTIFAVIYLFFTVGFMRHHTQSIKYKEENLVRRTLFITGLPRDAR 240

Query: 241 KETVESHFRDAYPTCEVVDVQLCYNVAKLIYLCKEKKKTEKSLTYYTNLQVKTGQRTLIN 300
           KETVESHFRDAYPTCEVVDVQLCYNVAKLIYLCKEKKKTEKSLTYYTNLQVKTGQRTLIN
Sbjct: 241 KETVESHFRDAYPTCEVVDVQLCYNVAKLIYLCKEKKKTEKSLTYYTNLQVKTGQRTLIN 300

Query: 301 PKPCGQFCCCEVLGCEWEDAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMA 360
           PKPCGQFCCCEVLGCEWEDAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMA
Sbjct: 301 PKPCGQFCCCEVLGCEWEDAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMA 360

Query: 361 TYILKDFNACKCQSLQCKGEPQPSSHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWL 420
           TYILKDFNACKCQSLQCKGEPQPSSHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWL
Sbjct: 361 TYILKDFNACKCQSLQCKGEPQPSSHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWL 420

Query: 421 QWLGINFTLFLGLFFLTTPSIILSTMDKFNVTKPIHALNNPIISQFFPTLLLWSFSALLP 480
           QWLGINFTLFLGLFFLTTPSIILSTMDKFNVTKPIHALNNPIISQFFPTLLLWSFSALLP
Sbjct: 421 QWLGINFTLFLGLFFLTTPSIILSTMDKFNVTKPIHALNNPIISQFFPTLLLWSFSALLP 480

Query: 481 SIVYYSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSEA 540
           SIVYYSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSEA
Sbjct: 481 SIVYYSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSEA 540

Query: 541 SIRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQN 600
           SIRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQN
Sbjct: 541 SIRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQN 600

Query: 601 QAFQYEFGAMYAWMLCVFTVIVAYSITCPIIAPFGLIYILLKHMVDRHNLYFVYLPAKLE 660
           QAFQYEFGAMYAWMLCVFTVIVAYSITCPIIAPFGLIYILLKHMVDRHNLYFVYLPAKLE
Sbjct: 601 QAFQYEFGAMYAWMLCVFTVIVAYSITCPIIAPFGLIYILLKHMVDRHNLYFVYLPAKLE 660

Query: 661 KGIHFAAVNQALAAPILCLFWLYFFSFLRLGMKAPATLFTFLVLLLTILVCLAHTCFGCF 720
           KGIHFAAVNQALAAPILCLFWLYFFSFLRLGMKAPATLFTFLVLLLTILVCLAHTCFGCF
Sbjct: 661 KGIHFAAVNQALAAPILCLFWLYFFSFLRLGMKAPATLFTFLVLLLTILVCLAHTCFGCF 720

Query: 721 KHLSPLNYKTEEPASDKGSEAEAHMPPPFTPYVPRILNGLASERTALSPQQQQQQTYGAI 780
           KHLSPLNYKTEEPASDKGSEAEAHMPPPFTPYVPRILNGLASERTALSPQQQQQQTYGAI
Sbjct: 721 KHLSPLNYKTEEPASDKGSEAEAHMPPPFTPYVPRILNGLASERTALSPQQQQQQTYGAI 780

Query: 781 HNISGTIPGQCLAQSATGSVAAAPQEA 807
           HNISGTIPGQCLAQSATGSVAAAPQEA
Sbjct: 781 HNISGTIPGQCLAQSATGSVAAAPQEA 807


>gi|55769589 transmembrane protein 63B [Homo sapiens]
          Length = 832

 Score =  923 bits (2385), Expect = 0.0
 Identities = 443/752 (58%), Positives = 568/752 (75%), Gaps = 26/752 (3%)

Query: 27  PNDSYCYNSAKNSTVLQGVTFGGIPTVLLIDVSCFLFLILVFSIIRRRFWDYGRIALVSE 86
           P D YCY++   STVLQG+ FGG+PTVL +D  CFL L+ +FSI+R+  WDYGR+ALV++
Sbjct: 19  PKD-YCYSARIRSTVLQGLPFGGVPTVLALDFMCFLALLFLFSILRKVAWDYGRLALVTD 77

Query: 87  AD----------------------SESRFQRLSSTSSSGQQDFENELGCCPWLTAIFRLH 124
           AD                      S  R++RL+S SSS   D + + G C WLTAIFR+ 
Sbjct: 78  ADRLRRQERDRVEQEYVASAMHGDSHDRYERLTSVSSSVDFD-QRDNGFCSWLTAIFRIK 136

Query: 125 DDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIA 184
           DD+I + CG DA+HYLSFQRHII LLVVV  LS+ ++LPVN SGDLL+ + YSFGRTTIA
Sbjct: 137 DDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDLLENNAYSFGRTTIA 196

Query: 185 NLQTDNDLLWLHTIFAVIYLFFTVGFMRHHTQSIKYKEENLVRRTLFITGLPRDARKETV 244
           NL++ N+LLWLHT FA +YL  TV  MR HT  ++YKE++LV+RTLFI G+ + A  E +
Sbjct: 197 NLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGISKYAESEKI 256

Query: 245 ESHFRDAYPTCEVVDVQLCYNVAKLIYLCKEKKKTEKSLTYYTNLQVKTGQRTLINPKPC 304
           + HF +AYP C V++ + CYNVA+L++L  E+KK E+   Y+TNLQ K    T+INPKPC
Sbjct: 257 KKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPTMINPKPC 316

Query: 305 GQFCCCEVLGCEWEDAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMATYIL 364
           G  CCC V GCE  +AI YYT+++ +L E    E+  V ++PLGMAFVTF  +++   IL
Sbjct: 317 GHLCCCVVRGCEQVEAIEYYTKLEQKLKEDYKREKEKVNEKPLGMAFVTFHNETITAIIL 376

Query: 365 KDFNACKCQSLQCKGEPQPSSHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWLQWLG 424
           KDFN CKCQ   C+GEP+PSS S  L+ S WTV++A DP++I W++LSI+G  WWL+ L 
Sbjct: 377 KDFNVCKCQGCTCRGEPRPSSCSESLHISNWTVSYAPDPQNIYWEHLSIRGFIWWLRCLV 436

Query: 425 INFTLFLGLFFLTTPSIILSTMDKFNVTKPIHALNNPIISQFFPTLLLWSFSALLPSIVY 484
           IN  LF+ LFFLTTP+II++TMDKFNVTKP+  LNNPII+QFFPTLLLW FSALLP+IVY
Sbjct: 437 INVVLFILLFFLTTPAIIITTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVY 496

Query: 485 YSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLFDKT-SSEASIR 543
           YS   E+HWT+SGEN+  M K Y FLIFMVL+LPSLGL+SLD FFRWLFDK   +EA+IR
Sbjct: 497 YSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIR 556

Query: 544 LECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAF 603
            ECVFLPD GAFFVNYVIASAFIGN M+LLR+PGL++Y  R+ +A++AA+RRNVK++QA+
Sbjct: 557 FECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAY 616

Query: 604 QYEFGAMYAWMLCVFTVIVAYSITCPIIAPFGLIYILLKHMVDRHNLYFVYLPAKLEKGI 663
           +++FGA YAWM+CVFTV++ YSITCPII PFGL+Y+LLKH+VDR+NLY+ YLPAKL+K I
Sbjct: 617 EFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKI 676

Query: 664 HFAAVNQALAAPILCLFWLYFFSFLRLGMKAPATLFTFLVLLLTILVCLAHTCFGCFKHL 723
           H  AVNQ +AAPILCLFWL FFS +R G  AP ++FTF+VL++TI++CL H CFG FK+L
Sbjct: 677 HSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYL 736

Query: 724 SPLNYKTEEPASDKGSEAEAHMPPPFTPYVPR 755
           S  NYK E   +D   +  ++  PP    VP+
Sbjct: 737 SAHNYKIEHTETDT-VDPRSNGRPPTAAAVPK 767


>gi|190341095 transmembrane protein 63C [Homo sapiens]
          Length = 806

 Score =  602 bits (1552), Expect = e-172
 Identities = 313/760 (41%), Positives = 464/760 (61%), Gaps = 20/760 (2%)

Query: 32  CYNSAKNSTVLQGVTFGGIPTVLLIDVSCFLFLILVFSIIRRRFWDYGRIALVSEADSES 91
           C+ S   +TVLQG  FGG+PTVL ++++ ++ +++V+S +R+  WDYGR+AL+   DS +
Sbjct: 22  CFQS--RNTVLQGQPFGGVPTVLCLNIALWVLVLVVYSFLRKAAWDYGRLALLIHNDSLT 79

Query: 92  R--FQRLSSTSSSGQQDFENEL---GCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHI 146
              +   S  +S  +   E E    G C W      + D+ ++  CG+DA  Y+ FQ H+
Sbjct: 80  SLIYGEQSEKTSPSETSLEMERRDKGFCSWFFNSITMKDEDLINKCGDDARIYIVFQYHL 139

Query: 147 IFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTDNDLLWLHTIFAVIYLFF 206
           I  ++++   SL +ILP+N +G +LD   + F RTTI N+ T++ LLWLH++ +  Y   
Sbjct: 140 IIFVLIICIPSLGIILPINYTGSVLDWSSH-FARTTIVNVSTESKLLWLHSLLSFFYFIT 198

Query: 207 TVGFMRHHTQSIKYKEENLVRRTLFITGLPRDARK-ETVESHFRDAYPTCEVVDVQLCYN 265
              FM HH      +    V RTL IT +P+D    E +  HF +AYP   V  V  CY+
Sbjct: 199 NFMFMAHHCLGFAPRNSQKVTRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYD 258

Query: 266 VAKLIYLCKEKKKTEKSLTYYTNLQVKTGQRTLINPKPCGQFCCCEVLGCEWE-DAISYY 324
           V  LI L  +++   +   +YT    KTG + +I   PC + C C+   C  E DA  YY
Sbjct: 259 VRNLIDLDDQRRHAMRGRLFYTAKAKKTG-KVMIRIHPCARLCFCKCWTCFKEVDAEQYY 317

Query: 325 TRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMATYILKDFNACKCQSLQCKGEPQPS 384
           + ++++L +    E   V  + L + FVTFQ+  MA  + KD+     + +QC  +PQ S
Sbjct: 318 SELEEQLTDEFNAELNRVPLKRLDLIFVTFQDSRMAKRVRKDY-----KYVQCGVQPQQS 372

Query: 385 SHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWLQWLGINFTLFLGLFFLTTPSIILS 444
           S +  + +  W VT A  P+DI WK+LS++   WW +++ IN  LF   FFLTTP+II++
Sbjct: 373 SVTTIVKSYYWRVTMAPHPKDIIWKHLSVRRFFWWARFIAINTFLFFLFFFLTTPAIIMN 432

Query: 445 TMDKFNVTKPIHALNNPIISQFFPTLLLWSFSALLPSIVYYSTLLESHWTKSGENQIMMT 504
           T+D +NVT+PI  L NPI++QFFP+++LW F+ +LP IVY+S  LE+HWT+S +N +M+ 
Sbjct: 433 TIDMYNVTRPIEKLQNPIVTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVH 492

Query: 505 KVYIFLIFMVLILPSLGLTSLDFFFRWLFDKTSSE-ASIRLECVFLPDQGAFFVNYVIAS 563
           K YIFL+FMV+ILPS+GLTSLD F RWLFD    E ASIR +CVFLPD GAFFVNYVI +
Sbjct: 493 KCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITA 552

Query: 564 AFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFQYEFGAMYAWMLCVFTVIVA 623
           A +G GMELLRL  L  Y+ R+  +++  +R N+++NQA  ++FG  YAWM+ VF+V++A
Sbjct: 553 ALLGTGMELLRLGSLFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMA 612

Query: 624 YSITCPIIAPFGLIYILLKHMVDRHNLYFVYLPAKLEKGIHFAAVNQALAAPILCLFWLY 683
           YSITCPII PFGL+Y+ +KH+ DR+N+Y+ + P KL + IH AAV+QA+ AP+L LFW+ 
Sbjct: 613 YSITCPIIVPFGLLYLCMKHLTDRYNMYYSFAPTKLNEQIHMAAVSQAIFAPLLGLFWML 672

Query: 684 FFSFLRLGMKAPATLFTFLVLLLTILVCLAHTCFGCFKHLSPLNYKTEEPASDKGSE-AE 742
           FFS LRLG     T+F+   LL+ +++       G  + ++    + EE  +    E + 
Sbjct: 673 FFSILRLGSLHAITIFSLSTLLIAMVIAFVGIFLGKLRMVADYEPEEEEIQTVFDMEPSS 732

Query: 743 AHMPPPFTPYVPRILNGLASERTALSPQQQQQQTYGAIHN 782
               P    YV  +L     E          + TYG ++N
Sbjct: 733 TSSTPTSLLYVATVLQ--EPELNLTPASSPARHTYGTMNN 770


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 31.6 bits (70), Expect = 3.1
 Identities = 16/34 (47%), Positives = 17/34 (50%)

Query: 755 RILNGLASERTALSPQQQQQQTYGAIHNISGTIP 788
           R+L G   E T L P   QQ   GA H  SGT P
Sbjct: 519 RLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSP 552


>gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo
            sapiens]
          Length = 1977

 Score = 31.2 bits (69), Expect = 4.0
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 319  DAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMATYILKDFNACKCQ-SLQC 377
            D ++  +++ D       EEE  ++  P    +   Q ++ A YIL+DFN  +C  + QC
Sbjct: 1748 DKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAYQC 1807


>gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo
            sapiens]
          Length = 1975

 Score = 31.2 bits (69), Expect = 4.0
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 319  DAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMATYILKDFNACKCQ-SLQC 377
            D ++  +++ D       EEE  ++  P    +   Q ++ A YIL+DFN  +C  + QC
Sbjct: 1746 DKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAYQC 1805


>gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo
            sapiens]
          Length = 1972

 Score = 31.2 bits (69), Expect = 4.0
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 319  DAISYYTRMKDRLLERITEEERHVQDQPLGMAFVTFQEKSMATYILKDFNACKCQ-SLQC 377
            D ++  +++ D       EEE  ++  P    +   Q ++ A YIL+DFN  +C  + QC
Sbjct: 1743 DKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAYQC 1802


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.139    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,056,047
Number of Sequences: 37866
Number of extensions: 1336039
Number of successful extensions: 4097
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 4077
Number of HSP's gapped (non-prelim): 8
length of query: 807
length of database: 18,247,518
effective HSP length: 110
effective length of query: 697
effective length of database: 14,082,258
effective search space: 9815333826
effective search space used: 9815333826
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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