Search of human proteins with 74101437

Search of human proteins with 74101437

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74101437 kynureninase (L-kynurenine hydrolase) isoform b
[Homo sapiens]
         (307 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74101437 kynureninase (L-kynurenine hydrolase) isoform b [Hom...   629   e-180
gi|4504937 kynureninase (L-kynurenine hydrolase) isoform a [Homo...   617   e-177
gi|45827765 UDP glycosyltransferase 1 family, polypeptide A6 iso...    30   2.7  
gi|221316741 N-acetyltransferase 10 isoform b [Homo sapiens]           29   4.6  
gi|221316723 N-acetyltransferase 10 isoform a [Homo sapiens]           29   4.6  
gi|30794488 kinesin family member 27 [Homo sapiens]                    29   4.6  
gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]              29   6.0  
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ...    29   6.0  

>gi|74101437 kynureninase (L-kynurenine hydrolase) isoform b [Homo
           sapiens]
          Length = 307

 Score =  629 bits (1621), Expect = e-180
 Identities = 307/307 (100%), Positives = 307/307 (100%)

Query: 1   MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60
           MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
Sbjct: 1   MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60

Query: 61  LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120
           LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
Sbjct: 61  LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120

Query: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180
           KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
Sbjct: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180

Query: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240
           LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
Sbjct: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240

Query: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300
           QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
Sbjct: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300

Query: 301 ARSEFFN 307
           ARSEFFN
Sbjct: 301 ARSEFFN 307


>gi|4504937 kynureninase (L-kynurenine hydrolase) isoform a [Homo
           sapiens]
          Length = 465

 Score =  617 bits (1590), Expect = e-177
 Identities = 302/306 (98%), Positives = 303/306 (99%)

Query: 1   MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60
           MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
Sbjct: 1   MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60

Query: 61  LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120
           LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
Sbjct: 61  LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120

Query: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180
           KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
Sbjct: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180

Query: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240
           LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
Sbjct: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240

Query: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300
           QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
Sbjct: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300

Query: 301 ARSEFF 306
           A   +F
Sbjct: 301 ALVGWF 306


>gi|45827765 UDP glycosyltransferase 1 family, polypeptide A6
           isoform 1 precursor [Homo sapiens]
          Length = 532

 Score = 30.0 bits (66), Expect = 2.7
 Identities = 17/65 (26%), Positives = 34/65 (52%), Gaps = 7/65 (10%)

Query: 176 LQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVI------LFSGVHFYTGQ 229
           L L G+ + + + ++ P++G   L ++DI+EV+   G  I V+      L     +YT +
Sbjct: 18  LALWGMVVGDKL-LVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKESKYYTRK 76

Query: 230 HFNIP 234
            + +P
Sbjct: 77  IYPVP 81


>gi|221316741 N-acetyltransferase 10 isoform b [Homo sapiens]
          Length = 953

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 13/33 (39%), Positives = 21/33 (63%)

Query: 52  QDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVK 84
           +DLPP+ L L  +    + +LG S GL P+++K
Sbjct: 617 KDLPPLLLKLNERPAERLDYLGVSYGLTPRLLK 649


>gi|221316723 N-acetyltransferase 10 isoform a [Homo sapiens]
          Length = 1025

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 13/33 (39%), Positives = 21/33 (63%)

Query: 52  QDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVK 84
           +DLPP+ L L  +    + +LG S GL P+++K
Sbjct: 689 KDLPPLLLKLNERPAERLDYLGVSYGLTPRLLK 721


>gi|30794488 kinesin family member 27 [Homo sapiens]
          Length = 1401

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 16/59 (27%), Positives = 30/59 (50%)

Query: 157  KILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSI 215
            K L  ++A  +D   I ++L L    + E    ++    EE  +I + +EV++KE D +
Sbjct: 972  KKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQL 1030


>gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]
          Length = 218

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 3/34 (8%)

Query: 81  KMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDE 114
           K+   YLEE  +K   +  Y   +GKRPW  GD+
Sbjct: 122 KLKPKYLEELPEK---LKLYSEFLGKRPWFAGDK 152


>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2
           [Homo sapiens]
          Length = 1235

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 18/46 (39%), Positives = 23/46 (50%)

Query: 170 YAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSI 215
           Y  +SQLQ   LNIE    M+     E   RI++  E I+K  D I
Sbjct: 731 YQEQSQLQSELLNIESQCIMLSEGIKERQRRIKEFQEKIDKVEDDI 776


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,796,694
Number of Sequences: 37866
Number of extensions: 514703
Number of successful extensions: 1099
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1093
Number of HSP's gapped (non-prelim): 8
length of query: 307
length of database: 18,247,518
effective HSP length: 102
effective length of query: 205
effective length of database: 14,385,186
effective search space: 2948963130
effective search space used: 2948963130
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.