Guide to the Human Genome
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Search of human proteins with 66933018

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66933018 indolethylamine N-methyltransferase [Homo sapiens]
         (263 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66933018 indolethylamine N-methyltransferase [Homo sapiens]        544   e-155
gi|5453790 nicotinamide N-methyltransferase [Homo sapiens]            270   9e-73
gi|4505921 phenylethanolamine N-methyltransferase [Homo sapiens]      178   5e-45
gi|41872631 fatty acid synthase [Homo sapiens]                         30   2.1  
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa...    29   4.8  
gi|21071030 alpha 1B-glycoprotein precursor [Homo sapiens]             28   6.2  

>gi|66933018 indolethylamine N-methyltransferase [Homo sapiens]
          Length = 263

 Score =  544 bits (1402), Expect = e-155
 Identities = 263/263 (100%), Positives = 263/263 (100%)

Query: 1   MKGGFTGGDEYQKHFLPRDYLATYYSFDGSPSPEAEMLKFNLECLHKTFGPGGLQGDTLI 60
           MKGGFTGGDEYQKHFLPRDYLATYYSFDGSPSPEAEMLKFNLECLHKTFGPGGLQGDTLI
Sbjct: 1   MKGGFTGGDEYQKHFLPRDYLATYYSFDGSPSPEAEMLKFNLECLHKTFGPGGLQGDTLI 60

Query: 61  DIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPGAYDWTPAVKFACELEGN 120
           DIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPGAYDWTPAVKFACELEGN
Sbjct: 61  DIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPGAYDWTPAVKFACELEGN 120

Query: 121 SGRWEEKEEKLRAAVKRVLKCDVHLGNPLAPAVLPLADCVLTLLAMECACCSLDAYRAAL 180
           SGRWEEKEEKLRAAVKRVLKCDVHLGNPLAPAVLPLADCVLTLLAMECACCSLDAYRAAL
Sbjct: 121 SGRWEEKEEKLRAAVKRVLKCDVHLGNPLAPAVLPLADCVLTLLAMECACCSLDAYRAAL 180

Query: 181 CNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEEVEQAVLDAGFDIEQLLHSPQ 240
           CNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEEVEQAVLDAGFDIEQLLHSPQ
Sbjct: 181 CNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEEVEQAVLDAGFDIEQLLHSPQ 240

Query: 241 SYSVTNAANNGVCFIVARKKPGP 263
           SYSVTNAANNGVCFIVARKKPGP
Sbjct: 241 SYSVTNAANNGVCFIVARKKPGP 263


>gi|5453790 nicotinamide N-methyltransferase [Homo sapiens]
          Length = 264

 Score =  270 bits (690), Expect = 9e-73
 Identities = 140/263 (53%), Positives = 178/263 (67%)

Query: 1   MKGGFTGGDEYQKHFLPRDYLATYYSFDGSPSPEAEMLKFNLECLHKTFGPGGLQGDTLI 60
           M+ GFT  D Y  HF PRDYL  YY F    S E+++LK  L+ L K F   G++GD LI
Sbjct: 1   MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLI 60

Query: 61  DIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPGAYDWTPAVKFACELEGN 120
           DIGSGPTIYQ+L+AC+SF++I ++D++D+N +ELEKWLKKEP A+DW+P V + C+LEGN
Sbjct: 61  DIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGN 120

Query: 121 SGRWEEKEEKLRAAVKRVLKCDVHLGNPLAPAVLPLADCVLTLLAMECACCSLDAYRAAL 180
             +  EKEEKLR AVK+VLKCDV    PL    LP ADCVL+ L ++ AC  L  Y  AL
Sbjct: 121 RVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRAL 180

Query: 181 CNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEEVEQAVLDAGFDIEQLLHSPQ 240
            NL SLLKPGG LV    L+   YM+G+++FS + L +E VE AV +AG+ IE      Q
Sbjct: 181 RNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQ 240

Query: 241 SYSVTNAANNGVCFIVARKKPGP 263
           SYS T A N G+  +VARK   P
Sbjct: 241 SYSSTMANNEGLFSLVARKLSRP 263


>gi|4505921 phenylethanolamine N-methyltransferase [Homo sapiens]
          Length = 282

 Score =  178 bits (451), Expect = 5e-45
 Identities = 96/234 (41%), Positives = 145/234 (61%), Gaps = 16/234 (6%)

Query: 11  YQKHFLPRDYLATYYSFDGSPSPEAEMLKFN------LECLHKTFGPGGLQGDTLIDIGS 64
           YQ+ F PR YL   Y+      P  ++   N      L CL +TF  G + G TLIDIGS
Sbjct: 27  YQR-FEPRAYLRNNYA-----PPRGDLCNPNGVGPWKLRCLAQTFATGEVSGRTLIDIGS 80

Query: 65  GPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPGAYDWTPAVKFACELEGNSGRW 124
           GPT+YQ+L+AC  F+DIT++DF + NR+EL +WL++EPGA++W+   + AC +EG    W
Sbjct: 81  GPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGAFNWSMYSQHACLIEGKGECW 140

Query: 125 EEKEEKLRAAVKRVLKCDVHLGNPL---APAVLPLADCVLTLLAMECACCSLDAYRAALC 181
           ++KE +LRA VKRVL  DVH   PL   +PA LP AD +++   +E     L +++ AL 
Sbjct: 141 QDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLP-ADALVSAFCLEAVSPDLASFQRALD 199

Query: 182 NLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEEVEQAVLDAGFDIEQL 235
           ++ +LL+PGGHL+    L    Y+ G+   + V + +EEV +A++ +G+ +  L
Sbjct: 200 HITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVREALVRSGYKVRDL 253


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 4/51 (7%)

Query: 150  APAVLPLADCVLTLLAMECACCSLDAYRAALCNLASLLKPGGHLVTTVTLR 200
            AP+ L  AD    LL   CA  +L    +AL N+ + L+ GG L+    LR
Sbjct: 1303 APSALGSAD----LLVCNCAVAALGDPASALSNMVAALREGGFLLLHTLLR 1349


>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
            sapiens]
          Length = 2881

 Score = 28.9 bits (63), Expect = 4.8
 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 2/42 (4%)

Query: 91   REELEKWLKKEPGAYDWTPAVKFACELEGNSGRWEEKEEKLR 132
            R++LEKWLK+ PG  +   A  F   ++ + GR ++K  + R
Sbjct: 2490 RKDLEKWLKEHPGYVEDLGA--FIPRMQLHEGRPKQKRHRCR 2529


>gi|21071030 alpha 1B-glycoprotein precursor [Homo sapiens]
          Length = 495

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 13/42 (30%), Positives = 15/42 (35%)

Query: 107 WTPAVKFACELEGNSGRWEEKEEKLRAAVKRVLKCDVHLGNP 148
           W P  + A   E     W E E  L+      L C  HL  P
Sbjct: 15  WGPVTEAAIFYETQPSLWAESESLLKPLANVTLTCQAHLETP 56


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,958,681
Number of Sequences: 37866
Number of extensions: 572679
Number of successful extensions: 1132
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1127
Number of HSP's gapped (non-prelim): 6
length of query: 263
length of database: 18,247,518
effective HSP length: 100
effective length of query: 163
effective length of database: 14,460,918
effective search space: 2357129634
effective search space used: 2357129634
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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