BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein [Homo sapiens] (244 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 517 e-147 gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 517 e-147 gi|61744426 kallikrein-related peptidase 6 isoform B [Homo sapiens] 298 3e-81 gi|11496281 kallikrein 13 precursor [Homo sapiens] 241 5e-64 gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 239 1e-63 gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 238 3e-63 gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 234 5e-62 gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 234 5e-62 gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 231 4e-61 gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 231 4e-61 gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 231 4e-61 gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 220 1e-57 gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 220 1e-57 gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 220 1e-57 gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 216 1e-56 gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 213 2e-55 gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 212 3e-55 gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 207 5e-54 gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 207 9e-54 gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 207 9e-54 gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 206 2e-53 gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 201 5e-52 gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 201 5e-52 gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 198 3e-51 gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 197 9e-51 gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 191 4e-49 gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 186 2e-47 gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 186 2e-47 gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 186 2e-47 gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 181 7e-46 >gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein [Homo sapiens] Length = 244 Score = 517 bits (1332), Expect = e-147 Identities = 244/244 (100%), Positives = 244/244 (100%) Query: 1 MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60 MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA Sbjct: 1 MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60 Query: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE Sbjct: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120 Query: 121 LIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNM 180 LIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNM Sbjct: 121 LIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNM 180 Query: 181 LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT 240 LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT Sbjct: 181 LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT 240 Query: 241 IQAK 244 IQAK Sbjct: 241 IQAK 244 >gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein [Homo sapiens] Length = 244 Score = 517 bits (1332), Expect = e-147 Identities = 244/244 (100%), Positives = 244/244 (100%) Query: 1 MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60 MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA Sbjct: 1 MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60 Query: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE Sbjct: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120 Query: 121 LIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNM 180 LIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNM Sbjct: 121 LIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNM 180 Query: 181 LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT 240 LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT Sbjct: 181 LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT 240 Query: 241 IQAK 244 IQAK Sbjct: 241 IQAK 244 >gi|61744426 kallikrein-related peptidase 6 isoform B [Homo sapiens] Length = 137 Score = 298 bits (763), Expect = 3e-81 Identities = 137/137 (100%), Positives = 137/137 (100%) Query: 108 MLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREE 167 MLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREE Sbjct: 1 MLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREE 60 Query: 168 CEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVY 227 CEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVY Sbjct: 61 CEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVY 120 Query: 228 TNVCRYTNWIQKTIQAK 244 TNVCRYTNWIQKTIQAK Sbjct: 121 TNVCRYTNWIQKTIQAK 137 >gi|11496281 kallikrein 13 precursor [Homo sapiens] Length = 277 Score = 241 bits (614), Expect = 5e-64 Identities = 118/225 (52%), Positives = 150/225 (66%), Gaps = 7/225 (3%) Query: 25 GGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQRESSQ 84 G C S P+QAAL G LLCGGVL+HP WVLTAAHC K L+V+LGKH L + E+ + Sbjct: 39 GYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGE 98 Query: 85 EQSSVVRAVIHPDYDAA----SHDQDIMLLRLARPAKLSELIQPLPLERDCSANT-TSCH 139 + VV ++ HP+Y + +HD DIMLL L P +L+ IQ LPL + T+C Sbjct: 99 QVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCR 158 Query: 140 ILGWGKTADG--DFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDS 197 + GWG T ++P T+QCA I L S EEC YPG+IT NMLCAG ++ GKDSC+GDS Sbjct: 159 VSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDS 218 Query: 198 GGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242 GGPLVC L G+VSWG+ PCG ++PGVYT V RY WI++TI+ Sbjct: 219 GGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263 >gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] Length = 260 Score = 239 bits (611), Expect = 1e-63 Identities = 115/251 (45%), Positives = 160/251 (63%), Gaps = 10/251 (3%) Query: 3 KLMVVLSLIAAAWA----EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVL 58 K + L L+ AWA +++K++ G C S P+QAAL+ LLCGGVL+ WVL Sbjct: 10 KTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVL 69 Query: 59 TAAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDY---DAASHDQDIMLLRLARP 115 TAAHCKKP V LG H+L+ ++ +++ VV+++ HP Y D H+ D+MLL+L Sbjct: 70 TAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQ 129 Query: 116 AKLSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECEHAYP 173 A L ++P+ L C+ C + GWG +FPDT+ CA + + +++CE AYP Sbjct: 130 ASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYP 189 Query: 174 GQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRY 233 GQIT M+CAG K G D+CQGDSGGPLVC L+G+ SWG+ PCG +KPGVYTN+CRY Sbjct: 190 GQITDGMVCAGSSK-GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRY 248 Query: 234 TNWIQKTIQAK 244 +WI+K I +K Sbjct: 249 LDWIKKIIGSK 259 >gi|91823048 kallikrein 14 preproprotein [Homo sapiens] Length = 267 Score = 238 bits (608), Expect = 3e-63 Identities = 114/248 (45%), Positives = 165/248 (66%), Gaps = 7/248 (2%) Query: 4 LMVVLSLIAAAWA---EEQNKLVHGGPCDKTSHPYQAALYTSGH--LLCGGVLIHPLWVL 58 L+ L ++A A E++NK++ G C ++S P+QAAL LCGG L+ WV+ Sbjct: 20 LLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVI 79 Query: 59 TAAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKL 118 TAAHC +P LQV LGKHNLR+ E++Q+ VVR V HP+Y++ +HD D+MLL+L +PA++ Sbjct: 80 TAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARI 139 Query: 119 SELIQPLPLERDCSANTTSCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPGQI 176 ++P+ + + C++ TSC + GWG + +P ++QC I++ E C+ AYP I Sbjct: 140 GRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTI 199 Query: 177 TQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNW 236 T M+CAG + GKDSCQGDSGGPLVC L+GLVSWG C PGVYTN+C+Y +W Sbjct: 200 TPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSW 259 Query: 237 IQKTIQAK 244 I++T++ K Sbjct: 260 IEETMRDK 267 >gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] Length = 305 Score = 234 bits (597), Expect = 5e-62 Identities = 109/232 (46%), Positives = 152/232 (65%), Gaps = 6/232 (2%) Query: 18 EQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNL 77 +++K++ G C S P+QAAL+ LLCGGVL+ WVLTAAHCKKP V LG H+L Sbjct: 74 QEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSL 133 Query: 78 RQRESSQEQSSVVRAVIHPDY---DAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAN 134 + ++ +++ VV+++ HP Y D H+ D+MLL+L A L ++P+ L C+ Sbjct: 134 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 193 Query: 135 TTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS 192 C + GWG +FPDT+ CA + + +++CE AYPGQIT M+CAG K G D+ Sbjct: 194 GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSK-GADT 252 Query: 193 CQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 244 CQGDSGGPLVC L+G+ SWG+ PCG +KPGVYTN+CRY +WI+K I +K Sbjct: 253 CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSK 304 >gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein [Homo sapiens] Length = 256 Score = 234 bits (597), Expect = 5e-62 Identities = 109/251 (43%), Positives = 158/251 (62%), Gaps = 12/251 (4%) Query: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63 L+ + L+A+ A++ +KL+ G C S P+Q ALY G CG LI P WVL+AAHC Sbjct: 4 LLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHC 63 Query: 64 KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ 123 + ++V LG+HNLR+R+ ++ + R + HP Y+A SH DIMLLRL +PA+L+ ++ Sbjct: 64 QSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVR 123 Query: 124 PLPLERDCSANTTSCHILGWGKTADGD------------FPDTIQCAYIHLVSREECEHA 171 P L C +C + GWG + + PDT+ CA I ++S C+ + Sbjct: 124 PAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKS 183 Query: 172 YPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVC 231 YPG++T M+CAG E G +SC+GDSGGPLVCG L+G+VSWG++PC + KPGVYT VC Sbjct: 184 YPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVC 243 Query: 232 RYTNWIQKTIQ 242 Y WI++T++ Sbjct: 244 HYLEWIRETMK 254 >gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] Length = 250 Score = 231 bits (589), Expect = 4e-61 Identities = 107/248 (43%), Positives = 154/248 (62%), Gaps = 6/248 (2%) Query: 1 MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60 M+ L ++L +A + +++ G C S P+QAAL+ LLCG LI P W+LTA Sbjct: 1 MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60 Query: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAA----SHDQDIMLLRLARPA 116 AHC KP V LG+HNL++ E ++ + + HP ++ + H DIML+++A P Sbjct: 61 AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 120 Query: 117 KLSELIQPLPLERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPG 174 ++ ++PL L C TSC I GWG T+ P T++CA I ++ ++CE+AYPG Sbjct: 121 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180 Query: 175 QITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYT 234 IT M+CA ++ GKDSCQGDSGGPLVC L+G++SWG PC KPGVYT VC+Y Sbjct: 181 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 240 Query: 235 NWIQKTIQ 242 +WIQ+T++ Sbjct: 241 DWIQETMK 248 >gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] Length = 282 Score = 231 bits (589), Expect = 4e-61 Identities = 107/248 (43%), Positives = 154/248 (62%), Gaps = 6/248 (2%) Query: 1 MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60 M+ L ++L +A + +++ G C S P+QAAL+ LLCG LI P W+LTA Sbjct: 33 MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92 Query: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAA----SHDQDIMLLRLARPA 116 AHC KP V LG+HNL++ E ++ + + HP ++ + H DIML+++A P Sbjct: 93 AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 152 Query: 117 KLSELIQPLPLERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPG 174 ++ ++PL L C TSC I GWG T+ P T++CA I ++ ++CE+AYPG Sbjct: 153 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212 Query: 175 QITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYT 234 IT M+CA ++ GKDSCQGDSGGPLVC L+G++SWG PC KPGVYT VC+Y Sbjct: 213 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 272 Query: 235 NWIQKTIQ 242 +WIQ+T++ Sbjct: 273 DWIQETMK 280 >gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] Length = 250 Score = 231 bits (589), Expect = 4e-61 Identities = 107/248 (43%), Positives = 154/248 (62%), Gaps = 6/248 (2%) Query: 1 MKKLMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60 M+ L ++L +A + +++ G C S P+QAAL+ LLCG LI P W+LTA Sbjct: 1 MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60 Query: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAA----SHDQDIMLLRLARPA 116 AHC KP V LG+HNL++ E ++ + + HP ++ + H DIML+++A P Sbjct: 61 AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 120 Query: 117 KLSELIQPLPLERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPG 174 ++ ++PL L C TSC I GWG T+ P T++CA I ++ ++CE+AYPG Sbjct: 121 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180 Query: 175 QITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYT 234 IT M+CA ++ GKDSCQGDSGGPLVC L+G++SWG PC KPGVYT VC+Y Sbjct: 181 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 240 Query: 235 NWIQKTIQ 242 +WIQ+T++ Sbjct: 241 DWIQETMK 248 >gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo sapiens] Length = 293 Score = 220 bits (560), Expect = 1e-57 Identities = 104/231 (45%), Positives = 148/231 (64%), Gaps = 5/231 (2%) Query: 17 EEQNKLVHGGPCDKTSHPYQAALYTS-GHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKH 75 + +++++G CD + P+QAAL L CG VL+HP W+LTAAHC+K +V LG + Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121 Query: 76 NLRQ-RESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAN 134 +L ES Q+ V+++ HP Y H D+ML++L R + ++ ++P+ + C + Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181 Query: 135 TTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS 192 T C + GWG T FP +QC I ++S++ CE AYP QI M CAGD K G+DS Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240 Query: 193 CQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243 CQGDSGGP+VC L+GLVSWG+ PC +PGVYTN+C++T WIQ+TIQA Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291 >gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo sapiens] Length = 293 Score = 220 bits (560), Expect = 1e-57 Identities = 104/231 (45%), Positives = 148/231 (64%), Gaps = 5/231 (2%) Query: 17 EEQNKLVHGGPCDKTSHPYQAALYTS-GHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKH 75 + +++++G CD + P+QAAL L CG VL+HP W+LTAAHC+K +V LG + Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121 Query: 76 NLRQ-RESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAN 134 +L ES Q+ V+++ HP Y H D+ML++L R + ++ ++P+ + C + Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181 Query: 135 TTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS 192 T C + GWG T FP +QC I ++S++ CE AYP QI M CAGD K G+DS Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240 Query: 193 CQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243 CQGDSGGP+VC L+GLVSWG+ PC +PGVYTN+C++T WIQ+TIQA Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291 >gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sapiens] Length = 293 Score = 220 bits (560), Expect = 1e-57 Identities = 104/231 (45%), Positives = 148/231 (64%), Gaps = 5/231 (2%) Query: 17 EEQNKLVHGGPCDKTSHPYQAALYTS-GHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKH 75 + +++++G CD + P+QAAL L CG VL+HP W+LTAAHC+K +V LG + Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121 Query: 76 NLRQ-RESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAN 134 +L ES Q+ V+++ HP Y H D+ML++L R + ++ ++P+ + C + Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181 Query: 135 TTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS 192 T C + GWG T FP +QC I ++S++ CE AYP QI M CAGD K G+DS Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240 Query: 193 CQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243 CQGDSGGP+VC L+GLVSWG+ PC +PGVYTN+C++T WIQ+TIQA Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291 >gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] Length = 248 Score = 216 bits (551), Expect = 1e-56 Identities = 112/240 (46%), Positives = 147/240 (61%), Gaps = 10/240 (4%) Query: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63 L+ VL L AA K+ +G C + S P+Q L+ L CGGVLI WVLTAAHC Sbjct: 8 LLCVLGLSQAATP----KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHC 63 Query: 64 KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAA--SHDQDIMLLRLARPAKLSEL 121 V LG+H+L Q + +++ +V HP Y A SH+ D+ LLRL P +++ Sbjct: 64 SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSS 123 Query: 122 IQPLPLERDCSANTTSCHILGWGKT--ADGDFPDTIQCAYIHLVSREECEHAYPGQITQN 179 +QPLPL DC+ T CH+ GWG T FPD +QC + +VS C YPG+IT N Sbjct: 124 VQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSN 183 Query: 180 MLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNI-PCGSKEKPGVYTNVCRYTNWIQ 238 M+CAG G+D+CQGDSGGPLVCG L+GLVSWG++ PCG PGVYT +C+Y +WI+ Sbjct: 184 MVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIR 242 >gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] Length = 247 Score = 213 bits (541), Expect = 2e-55 Identities = 106/244 (43%), Positives = 154/244 (63%), Gaps = 7/244 (2%) Query: 5 MVVLSLIAAAWA---EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAA 61 +++L+ +AAA A ++ +K+V G C++ S PYQ +L SG+ CGG LI+ WV++A Sbjct: 4 LLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQWVVSAG 62 Query: 62 HCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSEL 121 HC K +QV LG+HN+ E +++ + + + HP YD + + DIML++L+ A ++ Sbjct: 63 HCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAR 122 Query: 122 IQPLPLERDCSANTTSCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPGQITQN 179 + + L A T C I GWG TA D+PD +QC ++S+ +CE +YPG+IT N Sbjct: 123 VSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSN 182 Query: 180 MLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQK 239 M C G + GKDSCQGDSGGP+VC L+G+VSWG+ C K KPGVYT V Y WI+ Sbjct: 183 MFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKN 241 Query: 240 TIQA 243 TI A Sbjct: 242 TIAA 245 >gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] Length = 261 Score = 212 bits (539), Expect = 3e-55 Identities = 106/238 (44%), Positives = 146/238 (61%), Gaps = 13/238 (5%) Query: 19 QNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLR 78 Q+++V G C+K S P+Q A+Y+ G CGGVL+HP WVLTAAHC K N QV+LG+HNL Sbjct: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81 Query: 79 QRESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPL 127 + E + ++ V + HP Y+ + D+MLLRL+ PAK++++++ L L Sbjct: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141 Query: 128 ERDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGD 185 A T+C+ GWG +F P ++QC +HL+S + C AY ++T+ MLCAG Sbjct: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201 Query: 186 EKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243 GKD+C GDSGGPLVC L+G+ SWG PC EKP VYT V Y WI+ TI A Sbjct: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259 >gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] Length = 254 Score = 207 bits (528), Expect = 5e-54 Identities = 110/236 (46%), Positives = 142/236 (60%), Gaps = 10/236 (4%) Query: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63 L+ VL L AA K+ +G C + S P+Q L+ L CGGVLI WVLTAAHC Sbjct: 8 LLCVLGLSQAATP----KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHC 63 Query: 64 KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAA--SHDQDIMLLRLARPAKLSEL 121 V LG+H+L Q + +++ +V HP Y A SH+ D+ LLRL P +++ Sbjct: 64 SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSS 123 Query: 122 IQPLPLERDCSANTTSCHILGWGKT--ADGDFPDTIQCAYIHLVSREECEHAYPGQITQN 179 +QPLPL DC+ T CH+ GWG T FPD +QC + +VS C YPG+IT N Sbjct: 124 VQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSN 183 Query: 180 MLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNI-PCGSKEKPGVYTNVCRYT 234 M+CAG G+D+CQGDSGGPLVCG L+GLVSWG++ PCG PGVYT +C T Sbjct: 184 MVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICNST 238 >gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo sapiens] Length = 253 Score = 207 bits (526), Expect = 9e-54 Identities = 99/241 (41%), Positives = 142/241 (58%), Gaps = 4/241 (1%) Query: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63 L++ L+L A + +K++ G PC + SHP+Q AL + L CGGVL++ WVLTAAHC Sbjct: 12 LLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC 71 Query: 64 KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ 123 K V LG L R + + ++S ++ HP Y +H D+ML++L A+LS +++ Sbjct: 72 KMNEYTVHLGSDTLGDRRAQRIKAS--KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVK 129 Query: 124 PLPLERDCSANTTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNML 181 + L C T+C + GWG T D FP + C + L+S ++C Y + +ML Sbjct: 130 KVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSML 189 Query: 182 CAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241 CAG K++C GDSGGPLVC L+GLVSWG PCG PGVYT VC++T WI T+ Sbjct: 190 CAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 Query: 242 Q 242 + Sbjct: 250 K 250 >gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo sapiens] Length = 253 Score = 207 bits (526), Expect = 9e-54 Identities = 99/241 (41%), Positives = 142/241 (58%), Gaps = 4/241 (1%) Query: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63 L++ L+L A + +K++ G PC + SHP+Q AL + L CGGVL++ WVLTAAHC Sbjct: 12 LLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC 71 Query: 64 KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ 123 K V LG L R + + ++S ++ HP Y +H D+ML++L A+LS +++ Sbjct: 72 KMNEYTVHLGSDTLGDRRAQRIKAS--KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVK 129 Query: 124 PLPLERDCSANTTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNML 181 + L C T+C + GWG T D FP + C + L+S ++C Y + +ML Sbjct: 130 KVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSML 189 Query: 182 CAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241 CAG K++C GDSGGPLVC L+GLVSWG PCG PGVYT VC++T WI T+ Sbjct: 190 CAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 Query: 242 Q 242 + Sbjct: 250 K 250 >gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] Length = 247 Score = 206 bits (523), Expect = 2e-53 Identities = 104/245 (42%), Positives = 154/245 (62%), Gaps = 7/245 (2%) Query: 4 LMVVLSLIAAAWA---EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60 L+++L+ +AAA A ++ +K+V G C++ S PYQ +L SG+ CGG LI WV++A Sbjct: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWVVSA 61 Query: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120 HC K +QV LG+HN+ E +++ + + + HP Y++ + D DI+L++L+ PA ++ Sbjct: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINS 121 Query: 121 LIQPLPLERDCSANTTSCHILGWGKT--ADGDFPDTIQCAYIHLVSREECEHAYPGQITQ 178 + + L A T I GWG T + D+PD +QC ++S+ ECE +YPG+IT Sbjct: 122 RVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITN 181 Query: 179 NMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQ 238 NM C G + GKDSCQGDSGGP+V L+G+VSWG C K +PGVYT V Y +WI+ Sbjct: 182 NMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIK 240 Query: 239 KTIQA 243 TI A Sbjct: 241 DTIAA 245 >gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] Length = 247 Score = 201 bits (511), Expect = 5e-52 Identities = 100/243 (41%), Positives = 152/243 (62%), Gaps = 7/243 (2%) Query: 6 VVLSLIAAAWA---EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAH 62 ++L+ + AA A ++ +K+V G C++ S PYQ +L + H CGG LI WV++AAH Sbjct: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAH 63 Query: 63 CKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELI 122 C K +QV LG+HN++ E +++ + + + HP Y+ + D DIML++L+ PA ++ + Sbjct: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 123 Query: 123 QPLPLERDCSANTTSCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPGQITQNM 180 + L A T C I GWG T D+PD ++C ++++ EC+ +YPG+IT +M Sbjct: 124 STISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM 183 Query: 181 LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT 240 C G + GKDSCQ DSGGP+VC L+G+VSWG+ C K +PGVYT V Y +WI+ T Sbjct: 184 FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVDWIKDT 242 Query: 241 IQA 243 I A Sbjct: 243 IAA 245 >gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] Length = 250 Score = 201 bits (511), Expect = 5e-52 Identities = 108/246 (43%), Positives = 144/246 (58%), Gaps = 9/246 (3%) Query: 4 LMVVLSLIAA-AWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAH 62 L +LSL+A WA+ + + C S P+QA L+ L CG LI W+LTAAH Sbjct: 6 LCALLSLLAGHGWAD--TRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAH 63 Query: 63 CKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHP----DYDAASHDQDIMLLRLARPAKL 118 C+KP L V LG+H+L + E ++ V HP D A H+ DIML+RL R A+L Sbjct: 64 CRKPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARL 123 Query: 119 SELIQPLPLERDCSANTTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQI 176 S +QPL L + C + C I GWG + FP T+QCA I ++ + C AYPG I Sbjct: 124 SPAVQPLNLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHI 183 Query: 177 TQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNW 236 + +MLCAG + G+ SCQGDSGGPLVC L G+VS G PC +P VYT+VC Y +W Sbjct: 184 SDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDW 243 Query: 237 IQKTIQ 242 IQ+ ++ Sbjct: 244 IQEIME 249 >gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] Length = 304 Score = 198 bits (504), Expect = 3e-51 Identities = 96/229 (41%), Positives = 144/229 (62%), Gaps = 4/229 (1%) Query: 17 EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHN 76 ++ +K+V G C++ S PYQ +L + H CGG LI WV++AAHC K +QV LG+HN Sbjct: 76 DDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHN 134 Query: 77 LRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTT 136 ++ E +++ + + + HP Y+ + D DIML++L+ PA ++ + + L A T Sbjct: 135 IKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGT 194 Query: 137 SCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQ 194 C I GWG T D+PD ++C ++++ EC+ +YPG+IT +M C G + GKDSCQ Sbjct: 195 ECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQ 254 Query: 195 GDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243 DSGGP+VC L+G+VSWG+ C K +PGVYT V Y +WI+ TI A Sbjct: 255 RDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVDWIKDTIAA 302 >gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo sapiens] Length = 254 Score = 197 bits (500), Expect = 9e-51 Identities = 93/239 (38%), Positives = 137/239 (57%), Gaps = 1/239 (0%) Query: 6 VVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKK 65 ++L + + + +++++G C S P+QAAL L C GVL+HP WVL+AAHC + Sbjct: 15 LILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ 74 Query: 66 PNLQVFLGKHNLR-QRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP 124 + + LG H+L +E + +V HP+Y+ D+ML++L S+ I+ Sbjct: 75 NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRS 134 Query: 125 LPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAG 184 + + C SC + GWG A+G P +QC + +VS E C Y +M CAG Sbjct: 135 ISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAG 194 Query: 185 DEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243 KDSC GDSGGPL+C +L+GLVS+G PCG PGVYTN+C++T WI+KT+QA Sbjct: 195 GGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 >gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo sapiens] Length = 261 Score = 191 bits (486), Expect = 4e-49 Identities = 93/237 (39%), Positives = 137/237 (57%), Gaps = 13/237 (5%) Query: 20 NKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQ 79 +++V G C+K S P+Q + + G +CGGVL+HP WVLTAAHC + + LG+H+L Sbjct: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 Query: 80 RESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPLE 128 E + + V + HP YD + D+MLLRL+ PA+L++ ++ + L Sbjct: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 Query: 129 RDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDE 186 A T+C+ GWG +F P +QC +H++S + C +P ++T+ MLCAG Sbjct: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRW 202 Query: 187 KYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243 GK +C GDSGGPLVC L+G+ SWG+ PC E+P +YT V Y WI+ TI A Sbjct: 203 TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 >gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo sapiens] Length = 276 Score = 186 bits (472), Expect = 2e-47 Identities = 99/254 (38%), Positives = 141/254 (55%), Gaps = 22/254 (8%) Query: 10 LIAAAWAEEQNKL----------VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLT 59 L+A WA E L +G PC + S P+Q +L+ C GVL+ WVLT Sbjct: 24 LMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLT 83 Query: 60 AAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAAS--------HDQDIMLLR 111 AAHC L +G +L + Q + + R+V+HP Y S + D+MLL+ Sbjct: 84 AAHCGNKPLWARVGDDHLLLLQGEQLRRTT-RSVVHPKYHQGSGPILPRRTDEHDLMLLK 142 Query: 112 LARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECE 169 LARP L ++ L L C+ C + GWG TA + + C+ I ++S +ECE Sbjct: 143 LARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECE 202 Query: 170 HAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTN 229 YPG +T NM+CAG ++ G+D CQ DSGGPLVC + L+G++SWG PCGS + P VYT Sbjct: 203 VFYPGVVTNNMICAGLDR-GQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQ 261 Query: 230 VCRYTNWIQKTIQA 243 +C+Y +WI K I++ Sbjct: 262 ICKYMSWINKVIRS 275 >gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo sapiens] Length = 276 Score = 186 bits (472), Expect = 2e-47 Identities = 99/254 (38%), Positives = 141/254 (55%), Gaps = 22/254 (8%) Query: 10 LIAAAWAEEQNKL----------VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLT 59 L+A WA E L +G PC + S P+Q +L+ C GVL+ WVLT Sbjct: 24 LMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLT 83 Query: 60 AAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAAS--------HDQDIMLLR 111 AAHC L +G +L + Q + + R+V+HP Y S + D+MLL+ Sbjct: 84 AAHCGNKPLWARVGDDHLLLLQGEQLRRTT-RSVVHPKYHQGSGPILPRRTDEHDLMLLK 142 Query: 112 LARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECE 169 LARP L ++ L L C+ C + GWG TA + + C+ I ++S +ECE Sbjct: 143 LARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECE 202 Query: 170 HAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTN 229 YPG +T NM+CAG ++ G+D CQ DSGGPLVC + L+G++SWG PCGS + P VYT Sbjct: 203 VFYPGVVTNNMICAGLDR-GQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQ 261 Query: 230 VCRYTNWIQKTIQA 243 +C+Y +WI K I++ Sbjct: 262 ICKYMSWINKVIRS 275 >gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo sapiens] Length = 276 Score = 186 bits (472), Expect = 2e-47 Identities = 99/254 (38%), Positives = 141/254 (55%), Gaps = 22/254 (8%) Query: 10 LIAAAWAEEQNKL----------VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLT 59 L+A WA E L +G PC + S P+Q +L+ C GVL+ WVLT Sbjct: 24 LMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLT 83 Query: 60 AAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAAS--------HDQDIMLLR 111 AAHC L +G +L + Q + + R+V+HP Y S + D+MLL+ Sbjct: 84 AAHCGNKPLWARVGDDHLLLLQGEQLRRTT-RSVVHPKYHQGSGPILPRRTDEHDLMLLK 142 Query: 112 LARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECE 169 LARP L ++ L L C+ C + GWG TA + + C+ I ++S +ECE Sbjct: 143 LARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECE 202 Query: 170 HAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTN 229 YPG +T NM+CAG ++ G+D CQ DSGGPLVC + L+G++SWG PCGS + P VYT Sbjct: 203 VFYPGVVTNNMICAGLDR-GQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQ 261 Query: 230 VCRYTNWIQKTIQA 243 +C+Y +WI K I++ Sbjct: 262 ICKYMSWINKVIRS 275 >gi|4504875 kallikrein 1 preproprotein [Homo sapiens] Length = 262 Score = 181 bits (458), Expect = 7e-46 Identities = 90/237 (37%), Positives = 138/237 (58%), Gaps = 14/237 (5%) Query: 19 QNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLR 78 Q+++V G C++ S P+QAALY CGG+L+H WVLTAAHC N Q++LG+HNL Sbjct: 22 QSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLF 81 Query: 79 QRESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAK-LSELIQPLP 126 E++ + V + HP ++ + + D+MLLRL PA +++ ++ + Sbjct: 82 DDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVE 141 Query: 127 LERDCSANTTSCHILGWG--KTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAG 184 L + ++C GWG + + FPD +QC + ++ +EC+ A+ ++T MLC G Sbjct: 142 LPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVG 201 Query: 185 DEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241 + GKD+C GDSGGPL+C L+G+ SWG +PCG+ KP V V Y WI+ TI Sbjct: 202 HLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 258 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.135 0.435 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,621,377 Number of Sequences: 37866 Number of extensions: 495136 Number of successful extensions: 1556 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 170 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 909 Number of HSP's gapped (non-prelim): 199 length of query: 244 length of database: 18,247,518 effective HSP length: 99 effective length of query: 145 effective length of database: 14,498,784 effective search space: 2102323680 effective search space used: 2102323680 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.