Guide to the Human Genome
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Search of human proteins with 13540533

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13540533 N-acetylneuraminate pyruvate lyase [Homo sapiens]
         (320 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13540533 N-acetylneuraminate pyruvate lyase [Homo sapiens]         629   e-180
gi|31543060 DHDPS-like protein isoform 1 [Homo sapiens]                83   3e-16
gi|194306644 BCSC-1 isoform 1 [Homo sapiens]                           30   2.9  
gi|38195080 BCSC-1 isoform 1 [Homo sapiens]                            30   2.9  

>gi|13540533 N-acetylneuraminate pyruvate lyase [Homo sapiens]
          Length = 320

 Score =  629 bits (1621), Expect = e-180
 Identities = 320/320 (100%), Positives = 320/320 (100%)

Query: 1   MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSV 60
           MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSV
Sbjct: 1   MAFPKKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSV 60

Query: 61  SERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWT 120
           SERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWT
Sbjct: 61  SERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWT 120

Query: 121 KDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL 180
           KDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL
Sbjct: 121 KDILINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL 180

Query: 181 DFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFS 240
           DFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFS
Sbjct: 181 DFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFS 240

Query: 241 LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL 300
           LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL
Sbjct: 241 LALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKL 300

Query: 301 KSLDFLSFTDLKDGNLEAGS 320
           KSLDFLSFTDLKDGNLEAGS
Sbjct: 301 KSLDFLSFTDLKDGNLEAGS 320


>gi|31543060 DHDPS-like protein isoform 1 [Homo sapiens]
          Length = 327

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 84/306 (27%), Positives = 135/306 (44%), Gaps = 17/306 (5%)

Query: 5   KKKLQGLVAATITPMTENGEINFSVIGQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERR 64
           K  + G+     TP T   E+++  + + +  L      +   V G+ GE   L+ SER 
Sbjct: 32  KVDIAGIYPPVTTPFTATAEVDYGKLEENLHKLGTFP-FRGFVVQGSNGEFPFLTSSERL 90

Query: 65  QVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKP-WTKDI 123
           +V    V +   K   ++   G  S + + E+    A++GAD   V+ P + +   +   
Sbjct: 91  EVVSR-VRQAMPKNRLLLAGSGCESTQATVEMTVSMAQVGADAAMVVTPCYYRGRMSSAA 149

Query: 124 LINFLKEVAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLLDFG 183
           LI+   +VA  +P +P   Y +PA TG+ +  + ++   L + P   G+K S  D+   G
Sbjct: 150 LIHHYTKVADLSP-IPVVLYSVPANTGLDLPVDAVVT--LSQHPNIVGMKDSGGDVTRIG 206

Query: 184 QCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQMLEAFEQKDFSLAL 243
             V + R+Q F  L G    L+++  +GA G V +  N LG +  Q+        +  A 
Sbjct: 207 LIVHKTRKQDFQVLAGSAGFLMASYALGAVGGVCALANVLGAQVCQLERLCCTGQWEDAQ 266

Query: 244 NYQFCIQRFI--NFVVKLGFGVSQTKAIMTLVSGIPMGPPRLPLQKASREFTDSAEAKLK 301
             Q    R I  N  V   FG+   K IM    G   GP R PLQ+ S      AE +  
Sbjct: 267 KLQ---HRLIEPNAAVTRRFGIPGLKKIMDWF-GYYGGPCRAPLQELS-----PAEEEAL 317

Query: 302 SLDFLS 307
            +DF S
Sbjct: 318 RMDFTS 323


>gi|194306644 BCSC-1 isoform 1 [Homo sapiens]
          Length = 786

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 3/71 (4%)

Query: 174 FSDTDLLDFGQCVDQ---NRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQM 230
           F+D ++ D    + +   NRQ+   F FG+ E   ++L+ G   A G T  ++  K    
Sbjct: 392 FTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQ 451

Query: 231 LEAFEQKDFSL 241
            +A      SL
Sbjct: 452 SKALRTLKRSL 462


>gi|38195080 BCSC-1 isoform 1 [Homo sapiens]
          Length = 786

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 3/71 (4%)

Query: 174 FSDTDLLDFGQCVDQ---NRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQM 230
           F+D ++ D    + +   NRQ+   F FG+ E   ++L+ G   A G T  ++  K    
Sbjct: 392 FTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQ 451

Query: 231 LEAFEQKDFSL 241
            +A      SL
Sbjct: 452 SKALRTLKRSL 462


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,579,769
Number of Sequences: 37866
Number of extensions: 423822
Number of successful extensions: 938
Number of sequences better than 10.0: 4
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 934
Number of HSP's gapped (non-prelim): 4
length of query: 320
length of database: 18,247,518
effective HSP length: 102
effective length of query: 218
effective length of database: 14,385,186
effective search space: 3135970548
effective search space used: 3135970548
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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