Guide to the Human Genome
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Search of human proteins with 60499021

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|60499021 ferrochelatase isoform b precursor [Homo sapiens]
         (423 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|60499021 ferrochelatase isoform b precursor [Homo sapiens]         866   0.0  
gi|60499025 ferrochelatase isoform a precursor [Homo sapiens]         859   0.0  
gi|126131104 fibrocystin isoform 2 [Homo sapiens]                      30   3.2  
gi|126131102 fibrocystin isoform 1 [Homo sapiens]                      30   3.2  
gi|206597468 neural precursor cell expressed, developmentally do...    30   3.2  
gi|23097254 neural precursor cell expressed, developmentally dow...    30   3.2  
gi|206597465 neural precursor cell expressed, developmentally do...    30   3.2  
gi|239758065 PREDICTED: similar to BMS1-like, ribosome assembly ...    29   7.1  

>gi|60499021 ferrochelatase isoform b precursor [Homo sapiens]
          Length = 423

 Score =  866 bits (2237), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 1   MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV 60
           MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
Sbjct: 1   MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV 60

Query: 61  QPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQ 120
           QPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQ
Sbjct: 61  QPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQ 120

Query: 121 EQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERD 180
           EQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERD
Sbjct: 121 EQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERD 180

Query: 181 GLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADH 240
           GLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADH
Sbjct: 181 GLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADH 240

Query: 241 ILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLV 300
           ILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLV
Sbjct: 241 ILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLV 300

Query: 301 WQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKEC 360
           WQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKEC
Sbjct: 301 WQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKEC 360

Query: 361 GVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTS 420
           GVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTS
Sbjct: 361 GVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTS 420

Query: 421 QQL 423
           QQL
Sbjct: 421 QQL 423


>gi|60499025 ferrochelatase isoform a precursor [Homo sapiens]
          Length = 429

 Score =  859 bits (2220), Expect = 0.0
 Identities = 423/429 (98%), Positives = 423/429 (98%), Gaps = 6/429 (1%)

Query: 1   MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV 60
           MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
Sbjct: 1   MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV 60

Query: 61  QPQKR------KPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR 114
           QPQKR      KPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
Sbjct: 61  QPQKRYESNIRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR 120

Query: 115 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI 174
           RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
Sbjct: 121 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI 180

Query: 175 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI 234
           EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
Sbjct: 181 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI 240

Query: 235 QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC 294
           QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC
Sbjct: 241 QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC 300

Query: 295 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ 354
           NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
Sbjct: 301 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ 360

Query: 355 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET 414
           VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
Sbjct: 361 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET 420

Query: 415 KSFFTSQQL 423
           KSFFTSQQL
Sbjct: 421 KSFFTSQQL 429


>gi|126131104 fibrocystin isoform 2 [Homo sapiens]
          Length = 3396

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 3/72 (4%)

Query: 254 SEVVILFSAHSLPMSVVNRGDPYPQE-VSATVQKVMERLEYC--NPYRLVWQSKVGPMPW 310
           S+V +  SAH L   + N  D +    ++A+   V E L  C  + + L W +++G +P 
Sbjct: 802 SDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDLYTCYEHVWTLSWSTQIGDLPN 861

Query: 311 LGPQTDESIKGL 322
               +DE++ G+
Sbjct: 862 FIRVSDENLTGV 873


>gi|126131102 fibrocystin isoform 1 [Homo sapiens]
          Length = 4074

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 3/72 (4%)

Query: 254 SEVVILFSAHSLPMSVVNRGDPYPQE-VSATVQKVMERLEYC--NPYRLVWQSKVGPMPW 310
           S+V +  SAH L   + N  D +    ++A+   V E L  C  + + L W +++G +P 
Sbjct: 802 SDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDLYTCYEHVWTLSWSTQIGDLPN 861

Query: 311 LGPQTDESIKGL 322
               +DE++ G+
Sbjct: 862 FIRVSDENLTGV 873


>gi|206597468 neural precursor cell expressed, developmentally
           down-regulated 1 isoform b [Homo sapiens]
          Length = 660

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 4/39 (10%)

Query: 119 IQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPH 157
           +QE  R    G  IKIW +      + L+D+ +P+T+PH
Sbjct: 1   MQENLRFASSGDDIKIWDASS----MTLVDKFNPHTSPH 35


>gi|23097254 neural precursor cell expressed, developmentally
           down-regulated 1 isoform b [Homo sapiens]
          Length = 660

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 4/39 (10%)

Query: 119 IQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPH 157
           +QE  R    G  IKIW +      + L+D+ +P+T+PH
Sbjct: 1   MQENLRFASSGDDIKIWDASS----MTLVDKFNPHTSPH 35


>gi|206597465 neural precursor cell expressed, developmentally
           down-regulated 1 isoform a [Homo sapiens]
          Length = 667

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 4/39 (10%)

Query: 119 IQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPH 157
           +QE  R    G  IKIW +      + L+D+ +P+T+PH
Sbjct: 8   MQENLRFASSGDDIKIWDASS----MTLVDKFNPHTSPH 42


>gi|239758065 PREDICTED: similar to BMS1-like, ribosome assembly
           protein [Homo sapiens]
          Length = 331

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 8/106 (7%)

Query: 144 VKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQ--YPQYSCSTTGS 201
           +K++ +L P   P+K +    ++    E + E +E + L   I FT+  YP     +  +
Sbjct: 197 IKIVKKLKPTGFPYKIFKNTSFIKYGYESSFENVEVNYLFSDIVFTRTWYP----VSIPA 252

Query: 202 SLNAIYRYYNQVGRKPTMK--WSTIDRWPTHHLLIQCFADHILKEL 245
             N +      VG K T    W+T     TH + ++   D + K L
Sbjct: 253 FYNPVTSLLKPVGEKDTWSRTWTTGQLRLTHGVRLKANKDSLYKVL 298


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,977,245
Number of Sequences: 37866
Number of extensions: 780075
Number of successful extensions: 1622
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1616
Number of HSP's gapped (non-prelim): 8
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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