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Search of human proteins with 6005844
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
(260 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 561 e-160
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 539 e-154
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 268 4e-72
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 268 5e-72
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 268 5e-72
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 258 4e-69
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 255 3e-68
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 248 4e-66
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 248 4e-66
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 248 4e-66
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 248 5e-66
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 245 3e-65
gi|11496281 kallikrein 13 precursor [Homo sapiens] 243 2e-64
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 239 1e-63
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 239 1e-63
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 231 6e-61
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 224 4e-59
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 224 4e-59
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 219 2e-57
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 214 6e-56
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 214 6e-56
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 214 6e-56
gi|21464129 kallikrein 8 isoform 3 [Homo sapiens] 212 3e-55
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 210 9e-55
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 209 3e-54
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 203 1e-52
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 199 2e-51
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 199 2e-51
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 198 3e-51
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 198 4e-51
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 561 bits (1445), Expect = e-160
Identities = 260/260 (100%), Positives = 260/260 (100%)
Query: 1 MGRPRPRAAKTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGG 60
MGRPRPRAAKTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGG
Sbjct: 1 MGRPRPRAAKTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGG 60
Query: 61 VLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHD 120
VLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHD
Sbjct: 61 VLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHD 120
Query: 121 LMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFP 180
LMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFP
Sbjct: 121 LMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFP 180
Query: 181 QKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPG 240
QKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPG
Sbjct: 181 QKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPG 240
Query: 241 VYTNICRYLDWIKKIIGSKG 260
VYTNICRYLDWIKKIIGSKG
Sbjct: 241 VYTNICRYLDWIKKIIGSKG 260
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 539 bits (1389), Expect = e-154
Identities = 260/305 (85%), Positives = 260/305 (85%), Gaps = 45/305 (14%)
Query: 1 MGRPRPRAAKTWMFLLLLGGAWA------------------------------------- 23
MGRPRPRAAKTWMFLLLLGGAWA
Sbjct: 1 MGRPRPRAAKTWMFLLLLGGAWAACGSLDLLTKLYAENLPCVHLNPQWPSQPSHCPRGWR 60
Query: 24 --------GHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK 75
GHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK
Sbjct: 61 SNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK 120
Query: 76 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK 135
KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK
Sbjct: 121 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK 180
Query: 136 VKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG 195
VKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG
Sbjct: 181 VKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG 240
Query: 196 MVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKI 255
MVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKI
Sbjct: 241 MVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKI 300
Query: 256 IGSKG 260
IGSKG
Sbjct: 301 IGSKG 305
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 268 bits (685), Expect = 4e-72
Identities = 125/254 (49%), Positives = 170/254 (66%), Gaps = 4/254 (1%)
Query: 3 RPRPRAAKTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVL 62
R P A + L+LL A A E +++ G EC+PHSQPWQAALF+ +LLCG L
Sbjct: 26 RSSPLQAMRILQLILL--ALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATL 83
Query: 63 VGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSS-DVEDHNHDL 121
+ W+LTAAHC KP+Y V LG H+LQ ++G EQ +S PHP +N+S +DH +D+
Sbjct: 84 IAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDI 143
Query: 122 MLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQ 181
ML+++ S+ V+P++L+ C G C +SGWG+ +SP+ P TL CA + I
Sbjct: 144 MLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 203
Query: 182 KKCEDAYPGQITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPG 240
+KCE+AYPG ITD MVCA +G D+CQGDSGGPLVC+ +LQGI SWG DPC + KPG
Sbjct: 204 QKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPG 263
Query: 241 VYTNICRYLDWIKK 254
VYT +C+Y+DWI++
Sbjct: 264 VYTKVCKYVDWIQE 277
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 268 bits (684), Expect = 5e-72
Identities = 117/227 (51%), Positives = 160/227 (70%), Gaps = 2/227 (0%)
Query: 30 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89
E +++ G EC+PHSQPWQAALF+ +LLCG L+ W+LTAAHC KP+Y V LG H+LQ
Sbjct: 19 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 78
Query: 90 NKDGPEQEIPVVQSIPHPCYNSS-DVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 148
++G EQ +S PHP +N+S +DH +D+ML+++ S+ V+P++L+ C
Sbjct: 79 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 138
Query: 149 GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DT 207
G C +SGWG+ +SP+ P TL CA + I +KCE+AYPG ITD MVCA +G D+
Sbjct: 139 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 198
Query: 208 CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 254
CQGDSGGPLVC+ +LQGI SWG DPC + KPGVYT +C+Y+DWI++
Sbjct: 199 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQE 245
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 268 bits (684), Expect = 5e-72
Identities = 117/227 (51%), Positives = 160/227 (70%), Gaps = 2/227 (0%)
Query: 30 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89
E +++ G EC+PHSQPWQAALF+ +LLCG L+ W+LTAAHC KP+Y V LG H+LQ
Sbjct: 19 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 78
Query: 90 NKDGPEQEIPVVQSIPHPCYNSS-DVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 148
++G EQ +S PHP +N+S +DH +D+ML+++ S+ V+P++L+ C
Sbjct: 79 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 138
Query: 149 GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DT 207
G C +SGWG+ +SP+ P TL CA + I +KCE+AYPG ITD MVCA +G D+
Sbjct: 139 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 198
Query: 208 CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 254
CQGDSGGPLVC+ +LQGI SWG DPC + KPGVYT +C+Y+DWI++
Sbjct: 199 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQE 245
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 258 bits (659), Expect = 4e-69
Identities = 119/243 (48%), Positives = 157/243 (64%), Gaps = 8/243 (3%)
Query: 16 LLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK 75
LL G WA + + +G EC+P+SQPWQA LF +L CG L+ W+LTAAHC+
Sbjct: 12 LLAGHGWA------DTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCR 65
Query: 76 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSS-DVEDHNHDLMLLQLRDQASLGS 134
KP VRLG+H L +GPEQ V PHP +N DHN D+ML++L QA L
Sbjct: 66 KPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSP 125
Query: 135 KVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITD 194
V+P++L+ C PG +C +SGWG V+SP+ FP TL CA + I K C AYPG I+D
Sbjct: 126 AVQPLNLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISD 185
Query: 195 GMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIK 253
M+CAG +G +CQGDSGGPLVC+G L G+ S G++PC R +P VYT++C YLDWI+
Sbjct: 186 SMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQ 245
Query: 254 KII 256
+I+
Sbjct: 246 EIM 248
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 255 bits (651), Expect = 3e-68
Identities = 123/259 (47%), Positives = 164/259 (63%), Gaps = 8/259 (3%)
Query: 6 PRAAKTWMFLLLLGGAWAGHSRAQED--KVLGGHECQPHSQPWQAALFQG--QQLLCGGV 61
P A K ++ L L +++QED K++GGH C SQPWQAAL G ++ LCGG
Sbjct: 12 PSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGA 71
Query: 62 LVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDL 121
L+ G WV+TAAHC +P V LG H+L+ + +Q + VV+ + HP YNS H++DL
Sbjct: 72 LLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNS---RTHDNDL 128
Query: 122 MLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQ 181
MLLQL+ A +G V+PI + C PG C VSGWGT++SP +P +L C + I P
Sbjct: 129 MLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPD 188
Query: 182 KKCEDAYPGQITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPG 240
+ C+ AYP IT GMVCAG +G D+CQGDSGGPLVC G LQG+ SWG + C PG
Sbjct: 189 EVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPG 248
Query: 241 VYTNICRYLDWIKKIIGSK 259
VYTN+C+Y WI++ + K
Sbjct: 249 VYTNLCKYRSWIEETMRDK 267
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 248 bits (633), Expect = 4e-66
Identities = 117/242 (48%), Positives = 158/242 (65%), Gaps = 8/242 (3%)
Query: 20 GAWAGHSRAQED---KVLGGHECQPHSQPWQAA-LFQGQQLLCGGVLVGGNWVLTAAHCK 75
GA AG +D +++ G +C H+QPWQAA L + QL CG VLV W+LTAAHC+
Sbjct: 51 GAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCR 110
Query: 76 KPKYTVRLGDHSLQN-KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGS 134
K + VRLG +SL + +Q V+SIPHP Y+ H++DLML++L +
Sbjct: 111 KKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSH---PGHSNDLMLIKLNRRIRPTK 167
Query: 135 KVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITD 194
V+PI+++ HC G KC VSGWGT SP+ +FP L C + + QK+CEDAYP QI D
Sbjct: 168 DVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDD 227
Query: 195 GMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 254
M CAG G D+CQGDSGGP+VC+G+LQG+ SWG PC R ++PGVYTN+C++ WI++
Sbjct: 228 TMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
Query: 255 II 256
I
Sbjct: 288 TI 289
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 248 bits (633), Expect = 4e-66
Identities = 117/242 (48%), Positives = 158/242 (65%), Gaps = 8/242 (3%)
Query: 20 GAWAGHSRAQED---KVLGGHECQPHSQPWQAA-LFQGQQLLCGGVLVGGNWVLTAAHCK 75
GA AG +D +++ G +C H+QPWQAA L + QL CG VLV W+LTAAHC+
Sbjct: 51 GAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCR 110
Query: 76 KPKYTVRLGDHSLQN-KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGS 134
K + VRLG +SL + +Q V+SIPHP Y+ H++DLML++L +
Sbjct: 111 KKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSH---PGHSNDLMLIKLNRRIRPTK 167
Query: 135 KVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITD 194
V+PI+++ HC G KC VSGWGT SP+ +FP L C + + QK+CEDAYP QI D
Sbjct: 168 DVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDD 227
Query: 195 GMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 254
M CAG G D+CQGDSGGP+VC+G+LQG+ SWG PC R ++PGVYTN+C++ WI++
Sbjct: 228 TMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
Query: 255 II 256
I
Sbjct: 288 TI 289
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 248 bits (633), Expect = 4e-66
Identities = 117/242 (48%), Positives = 158/242 (65%), Gaps = 8/242 (3%)
Query: 20 GAWAGHSRAQED---KVLGGHECQPHSQPWQAA-LFQGQQLLCGGVLVGGNWVLTAAHCK 75
GA AG +D +++ G +C H+QPWQAA L + QL CG VLV W+LTAAHC+
Sbjct: 51 GAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCR 110
Query: 76 KPKYTVRLGDHSLQN-KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGS 134
K + VRLG +SL + +Q V+SIPHP Y+ H++DLML++L +
Sbjct: 111 KKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSH---PGHSNDLMLIKLNRRIRPTK 167
Query: 135 KVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITD 194
V+PI+++ HC G KC VSGWGT SP+ +FP L C + + QK+CEDAYP QI D
Sbjct: 168 DVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDD 227
Query: 195 GMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 254
M CAG G D+CQGDSGGP+VC+G+LQG+ SWG PC R ++PGVYTN+C++ WI++
Sbjct: 228 TMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
Query: 255 II 256
I
Sbjct: 288 TI 289
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 248 bits (632), Expect = 5e-66
Identities = 121/254 (47%), Positives = 163/254 (64%), Gaps = 15/254 (5%)
Query: 13 MFLLLLGGAWAGHSRAQE-DKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTA 71
M+LLL + AQ+ DK+L G EC PHSQPWQ AL++ + CG L+ +WVL+A
Sbjct: 1 MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA 60
Query: 72 AHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQAS 131
AHC+ VRLG+H+L+ +DGPEQ + IPHP Y + H +D+MLL+L A
Sbjct: 61 AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRY---EARSHRNDIMLLRLVQPAR 117
Query: 132 LGSKVKPISLADHCTQPGQKCTVSGWGTVT--------SPRE--NFPDTLNCAEVKIFPQ 181
L +V+P L C PG+ C VSGWG V+ SPR + PDTL+CA + I
Sbjct: 118 LNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISD 177
Query: 182 KKCEDAYPGQITDGMVCAGS-SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPG 240
C+ +YPG++T+ MVCAG+ +GA++C+GDSGGPLVC G LQGI SWG PC + KPG
Sbjct: 178 TSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPG 237
Query: 241 VYTNICRYLDWIKK 254
VYT +C YL+WI++
Sbjct: 238 VYTKVCHYLEWIRE 251
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 245 bits (625), Expect = 3e-65
Identities = 123/245 (50%), Positives = 147/245 (60%), Gaps = 5/245 (2%)
Query: 13 MFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAA 72
+FLLL G S+A K+ G EC +SQPWQ LF+G L CGGVL+ WVLTAA
Sbjct: 5 IFLLL---CVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAA 61
Query: 73 HCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASL 132
HC +Y VRLG+HSL D EQ S+ HP Y + H HDL LL+LR +
Sbjct: 62 HCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTS-HEHDLRLLRLRLPVRV 120
Query: 133 GSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQI 192
S V+P+ L + C G +C VSGWG PR FPD L C + I C YPG+I
Sbjct: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180
Query: 193 TDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGS-DPCGRSDKPGVYTNICRYLDW 251
T MVCAG G D CQGDSGGPLVC G LQG+ SWGS PCG+ PGVYT IC+Y+DW
Sbjct: 181 TSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDW 240
Query: 252 IKKII 256
I+ I+
Sbjct: 241 IRMIM 245
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 243 bits (619), Expect = 2e-64
Identities = 116/225 (51%), Positives = 151/225 (67%), Gaps = 3/225 (1%)
Query: 35 GGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGP 94
GG+ C PHSQPWQAAL +LLCGGVLV WVLTAAHC K V LG H+L +
Sbjct: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
Query: 95 EQEIPVVQSIPHPCYNSSDVE-DHNHDLMLLQLRDQASLGSKVKPISLA-DHCTQPGQKC 152
EQ VV SIPHP Y S +H+HD+MLL+L+ L ++ + L+ ++ PG C
Sbjct: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
Query: 153 TVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTCQGD 211
VSGWGT TSP+ N+P TL CA +++ ++C YPG+ITD M+CAG+ +G D+C+GD
Sbjct: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
Query: 212 SGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 256
SGGPLVC+ L GI SWG PCG+ D+PGVYT + RY+ WI++ I
Sbjct: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 239 bits (611), Expect = 1e-63
Identities = 115/251 (45%), Positives = 160/251 (63%), Gaps = 10/251 (3%)
Query: 10 KTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVL 69
K + L L+ AWA +++K++ G C S P+QAAL+ LLCGGVL+ WVL
Sbjct: 3 KLMVVLSLIAAAWA----EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVL 58
Query: 70 TAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQ 129
TAAHCKKP V LG H+L+ ++ +++ VV+++ HP Y D H+ D+MLL+L
Sbjct: 59 TAAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDY---DAASHDQDIMLLRLARP 115
Query: 130 ASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYP 189
A L ++P+ L C+ C + GWG +FPDT+ CA + + +++CE AYP
Sbjct: 116 AKLSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECEHAYP 173
Query: 190 GQITDGMVCAGSSK-GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRY 248
GQIT M+CAG K G D+CQGDSGGPLVC L+G+ SWG+ PCG +KPGVYTN+CRY
Sbjct: 174 GQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRY 233
Query: 249 LDWIKKIIGSK 259
+WI+K I +K
Sbjct: 234 TNWIQKTIQAK 244
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 239 bits (611), Expect = 1e-63
Identities = 115/251 (45%), Positives = 160/251 (63%), Gaps = 10/251 (3%)
Query: 10 KTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVL 69
K + L L+ AWA +++K++ G C S P+QAAL+ LLCGGVL+ WVL
Sbjct: 3 KLMVVLSLIAAAWA----EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVL 58
Query: 70 TAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQ 129
TAAHCKKP V LG H+L+ ++ +++ VV+++ HP Y D H+ D+MLL+L
Sbjct: 59 TAAHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDY---DAASHDQDIMLLRLARP 115
Query: 130 ASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYP 189
A L ++P+ L C+ C + GWG +FPDT+ CA + + +++CE AYP
Sbjct: 116 AKLSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECEHAYP 173
Query: 190 GQITDGMVCAGSSK-GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRY 248
GQIT M+CAG K G D+CQGDSGGPLVC L+G+ SWG+ PCG +KPGVYTN+CRY
Sbjct: 174 GQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRY 233
Query: 249 LDWIKKIIGSK 259
+WI+K I +K
Sbjct: 234 TNWIQKTIQAK 244
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 231 bits (588), Expect = 6e-61
Identities = 118/235 (50%), Positives = 138/235 (58%), Gaps = 5/235 (2%)
Query: 13 MFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAA 72
+FLLL G S+A K+ G EC +SQPWQ LF+G L CGGVL+ WVLTAA
Sbjct: 5 IFLLL---CVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAA 61
Query: 73 HCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASL 132
HC +Y VRLG+HSL D EQ S+ HP Y + H HDL LL+LR +
Sbjct: 62 HCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTS-HEHDLRLLRLRLPVRV 120
Query: 133 GSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQI 192
S V+P+ L + C G +C VSGWG PR FPD L C + I C YPG+I
Sbjct: 121 TSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI 180
Query: 193 TDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGS-DPCGRSDKPGVYTNIC 246
T MVCAG G D CQGDSGGPLVC G LQG+ SWGS PCG+ PGVYT IC
Sbjct: 181 TSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYIC 235
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 224 bits (572), Expect = 4e-59
Identities = 117/243 (48%), Positives = 145/243 (59%), Gaps = 11/243 (4%)
Query: 13 MFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAA 72
+ LL L AG AQ DK++ G C S PWQ AL G QL CGGVLV WVLTAA
Sbjct: 11 ILLLSLALETAGEE-AQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAA 69
Query: 73 HCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASL 132
HCK +YTV LG +L ++ Q I +S HP Y++ + H +DLML++L QA L
Sbjct: 70 HCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST---QTHVNDLMLVKLNSQARL 124
Query: 133 GSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQI 192
S VK + L C PG CTVSGWGT TSP FP L C +VK+ + C Y +
Sbjct: 125 SSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLL 184
Query: 193 TDGMVCAG---SSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYL 249
+ M+CAG S K A C GDSGGPLVC G LQG+ SWG+ PCG+ + PGVYT +C++
Sbjct: 185 ENSMLCAGIPDSKKNA--CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242
Query: 250 DWI 252
WI
Sbjct: 243 KWI 245
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 224 bits (572), Expect = 4e-59
Identities = 117/243 (48%), Positives = 145/243 (59%), Gaps = 11/243 (4%)
Query: 13 MFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAA 72
+ LL L AG AQ DK++ G C S PWQ AL G QL CGGVLV WVLTAA
Sbjct: 11 ILLLSLALETAGEE-AQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAA 69
Query: 73 HCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASL 132
HCK +YTV LG +L ++ Q I +S HP Y++ + H +DLML++L QA L
Sbjct: 70 HCKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYST---QTHVNDLMLVKLNSQARL 124
Query: 133 GSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQI 192
S VK + L C PG CTVSGWGT TSP FP L C +VK+ + C Y +
Sbjct: 125 SSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLL 184
Query: 193 TDGMVCAG---SSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYL 249
+ M+CAG S K A C GDSGGPLVC G LQG+ SWG+ PCG+ + PGVYT +C++
Sbjct: 185 ENSMLCAGIPDSKKNA--CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242
Query: 250 DWI 252
WI
Sbjct: 243 KWI 245
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 219 bits (558), Expect = 2e-57
Identities = 109/257 (42%), Positives = 152/257 (59%), Gaps = 12/257 (4%)
Query: 12 WMFLLLLGGAWAGHSRAQ--EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVL 69
W +L L + G A + +++GG EC+ HSQPWQAAL+ CGG+LV WVL
Sbjct: 2 WFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVL 61
Query: 70 TAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDH--------NHDL 121
TAAHC Y + LG H+L + + Q + V +S PHP +N S +E+H +HDL
Sbjct: 62 TAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDL 121
Query: 122 MLLQLRDQA-SLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFP 180
MLL+L + A ++ VK + L + G C SGWG++ +FPD L C ++KI P
Sbjct: 122 MLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILP 181
Query: 181 QKKCEDAYPGQITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKP 239
+C+ A+ ++TD M+C G +G DTC GDSGGPL+CDG LQG+TSWG PCG +KP
Sbjct: 182 NDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKP 241
Query: 240 GVYTNICRYLDWIKKII 256
V + Y+ WI+ I
Sbjct: 242 SVAVRVLSYVKWIEDTI 258
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 214 bits (545), Expect = 6e-56
Identities = 112/254 (44%), Positives = 139/254 (54%), Gaps = 12/254 (4%)
Query: 16 LLLGGAWAGHSRA--QEDKVLG----GHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVL 69
LL+ WA + Q D L G C SQPWQ +LF G C GVLV +WVL
Sbjct: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
Query: 70 TAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDV-----EDHNHDLMLL 124
TAAHC R+GD L G EQ +S+ HP Y+ HDLMLL
Sbjct: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
Query: 125 QLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKC 184
+L LG +V+ + L C QPG +C V+GWGT + R + L C+ + I K+C
Sbjct: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
Query: 185 EDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTN 244
E YPG +T+ M+CAG +G D CQ DSGGPLVCD LQGI SWG PCG + P VYT
Sbjct: 202 EVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQ 261
Query: 245 ICRYLDWIKKIIGS 258
IC+Y+ WI K+I S
Sbjct: 262 ICKYMSWINKVIRS 275
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 214 bits (545), Expect = 6e-56
Identities = 112/254 (44%), Positives = 139/254 (54%), Gaps = 12/254 (4%)
Query: 16 LLLGGAWAGHSRA--QEDKVLG----GHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVL 69
LL+ WA + Q D L G C SQPWQ +LF G C GVLV +WVL
Sbjct: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
Query: 70 TAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDV-----EDHNHDLMLL 124
TAAHC R+GD L G EQ +S+ HP Y+ HDLMLL
Sbjct: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
Query: 125 QLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKC 184
+L LG +V+ + L C QPG +C V+GWGT + R + L C+ + I K+C
Sbjct: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
Query: 185 EDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTN 244
E YPG +T+ M+CAG +G D CQ DSGGPLVCD LQGI SWG PCG + P VYT
Sbjct: 202 EVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQ 261
Query: 245 ICRYLDWIKKIIGS 258
IC+Y+ WI K+I S
Sbjct: 262 ICKYMSWINKVIRS 275
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 214 bits (545), Expect = 6e-56
Identities = 112/254 (44%), Positives = 139/254 (54%), Gaps = 12/254 (4%)
Query: 16 LLLGGAWAGHSRA--QEDKVLG----GHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVL 69
LL+ WA + Q D L G C SQPWQ +LF G C GVLV +WVL
Sbjct: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
Query: 70 TAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDV-----EDHNHDLMLL 124
TAAHC R+GD L G EQ +S+ HP Y+ HDLMLL
Sbjct: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
Query: 125 QLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKC 184
+L LG +V+ + L C QPG +C V+GWGT + R + L C+ + I K+C
Sbjct: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
Query: 185 EDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTN 244
E YPG +T+ M+CAG +G D CQ DSGGPLVCD LQGI SWG PCG + P VYT
Sbjct: 202 EVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQ 261
Query: 245 ICRYLDWIKKIIGS 258
IC+Y+ WI K+I S
Sbjct: 262 ICKYMSWINKVIRS 275
>gi|21464129 kallikrein 8 isoform 3 [Homo sapiens]
Length = 119
Score = 212 bits (539), Expect = 3e-55
Identities = 96/96 (100%), Positives = 96/96 (100%)
Query: 165 ENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQG 224
ENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQG
Sbjct: 24 ENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQG 83
Query: 225 ITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG 260
ITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG
Sbjct: 84 ITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG 119
Score = 53.5 bits (127), Expect = 2e-07
Identities = 23/23 (100%), Positives = 23/23 (100%)
Query: 1 MGRPRPRAAKTWMFLLLLGGAWA 23
MGRPRPRAAKTWMFLLLLGGAWA
Sbjct: 1 MGRPRPRAAKTWMFLLLLGGAWA 23
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 210 bits (535), Expect = 9e-55
Identities = 99/230 (43%), Positives = 144/230 (62%), Gaps = 6/230 (2%)
Query: 30 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++A HC K + VRLG+H+++
Sbjct: 21 DDKIVGGYNCEENSVPYQVSLNSGYHF-CGGSLINEQWVVSAGHCYKSRIQVRLGEHNIE 79
Query: 90 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 149
+G EQ I + I HP Y+ + N+D+ML++L +A + ++V ISL G
Sbjct: 80 VLEGNEQFINAAKIIRHPQYDRKTL---NNDIMLIKLSSRAVINARVSTISLPTAPPATG 136
Query: 150 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 208
KC +SGWG S ++PD L C + + Q KCE +YPG+IT M C G +G D+C
Sbjct: 137 TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSC 196
Query: 209 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 258
QGDSGGP+VC+G LQG+ SWG D C + +KPGVYT + Y+ WIK I +
Sbjct: 197 QGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAA 245
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 209 bits (531), Expect = 3e-54
Identities = 105/238 (44%), Positives = 136/238 (57%), Gaps = 9/238 (3%)
Query: 30 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89
+ +++GG EC+ HSQPWQ A++ CGGVLV WVLTAAHC K V LG H+L
Sbjct: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
Query: 90 NKDGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISL 141
+ Q +PV S PHP YN S + ED +HDLMLL+L + A + VK + L
Sbjct: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
Query: 142 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS 201
G C SGWG++ P +L C + + C AY ++T+ M+CAG
Sbjct: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
Query: 202 -SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 258
+ G DTC GDSGGPLVC+G LQGITSWG +PC +KP VYT + Y WIK I +
Sbjct: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 203 bits (517), Expect = 1e-52
Identities = 103/250 (41%), Positives = 138/250 (55%), Gaps = 9/250 (3%)
Query: 16 LLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK 75
L L W G + +++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC
Sbjct: 8 LTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI 67
Query: 76 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLR 127
+ K + LG HSL + + Q V S PHP Y+ S + +D +HDLMLL+L
Sbjct: 68 RNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS 127
Query: 128 DQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDA 187
+ A L VK + L G C SGWG++ P L C ++ + C
Sbjct: 128 EPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV 187
Query: 188 YPGQITDGMVCAGS-SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNIC 246
+P ++T M+CAG + G TC GDSGGPLVC+G LQGITSWGS+PC ++P +YT +
Sbjct: 188 HPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVV 247
Query: 247 RYLDWIKKII 256
Y WIK I
Sbjct: 248 HYRKWIKDTI 257
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 199 bits (507), Expect = 2e-51
Identities = 95/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 30 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++AAHC K + VRLG+H+++
Sbjct: 78 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 136
Query: 90 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 149
+G EQ I + I HP YN +++ D+ML++L A + ++V ISL G
Sbjct: 137 VLEGNEQFINAAKIIRHPKYNRDTLDN---DIMLIKLSSPAVINARVSTISLPTAPPAAG 193
Query: 150 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 208
+C +SGWG S ++PD L C + + Q +C+ +YPG+IT+ M C G +G D+C
Sbjct: 194 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 253
Query: 209 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 258
Q DSGGP+VC+G LQG+ SWG C ++PGVYT + Y+DWIK I +
Sbjct: 254 QRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAA 302
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 199 bits (507), Expect = 2e-51
Identities = 95/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 30 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++AAHC K + VRLG+H+++
Sbjct: 21 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 79
Query: 90 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 149
+G EQ I + I HP YN +++ D+ML++L A + ++V ISL G
Sbjct: 80 VLEGNEQFINAAKIIRHPKYNRDTLDN---DIMLIKLSSPAVINARVSTISLPTAPPAAG 136
Query: 150 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 208
+C +SGWG S ++PD L C + + Q +C+ +YPG+IT+ M C G +G D+C
Sbjct: 137 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 196
Query: 209 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 258
Q DSGGP+VC+G LQG+ SWG C ++PGVYT + Y+DWIK I +
Sbjct: 197 QRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAA 245
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 198 bits (504), Expect = 3e-51
Identities = 96/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 30 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++A HC K + VRLG+H+++
Sbjct: 21 DDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSAGHCYKSRIQVRLGEHNIE 79
Query: 90 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 149
+G EQ I + I HP YNS +++ D++L++L A + S+V ISL G
Sbjct: 80 VLEGNEQFINAAKIIRHPKYNSRTLDN---DILLIKLSSPAVINSRVSAISLPTAPPAAG 136
Query: 150 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 208
+ +SGWG S ++PD L C + + Q +CE +YPG+IT+ M C G +G D+C
Sbjct: 137 TESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSC 196
Query: 209 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 258
QGDSGGP+V +G LQGI SWG C + ++PGVYT + Y+DWIK I +
Sbjct: 197 QGDSGGPVVSNGELQGIVSWGYG-CAQKNRPGVYTKVYNYVDWIKDTIAA 245
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 198 bits (503), Expect = 4e-51
Identities = 99/247 (40%), Positives = 136/247 (55%), Gaps = 7/247 (2%)
Query: 12 WMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTA 71
W L+ G +++ G +C PHSQPWQAAL +L C GVLV WVL+A
Sbjct: 10 WFLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSA 69
Query: 72 AHCKKPKYTVRLGDHSLQNKDGP-EQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQA 130
AHC + YT+ LG HSL+ P Q + S+ HP YN + + DLML++L +
Sbjct: 70 AHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLAN---DLMLIKLDESV 126
Query: 131 SLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPG 190
S ++ IS+A C G C VSGWG + + R P L C V + ++ C Y
Sbjct: 127 SESDTIRSISIASQCPTAGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDP 184
Query: 191 QITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYL 249
M CAG D+C GDSGGPL+C+G LQG+ S+G PCG+ PGVYTN+C++
Sbjct: 185 LYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFT 244
Query: 250 DWIKKII 256
+WI+K +
Sbjct: 245 EWIEKTV 251
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,344,386
Number of Sequences: 37866
Number of extensions: 600574
Number of successful extensions: 1932
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1216
Number of HSP's gapped (non-prelim): 246
length of query: 260
length of database: 18,247,518
effective HSP length: 100
effective length of query: 160
effective length of database: 14,460,918
effective search space: 2313746880
effective search space used: 2313746880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.