Search of human proteins with 54607120

Search of human proteins with 54607120

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54607120 lactotransferrin precursor [Homo sapiens]
         (710 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54607120 lactotransferrin precursor [Homo sapiens]                1465   0.0  
gi|4557871 transferrin [Homo sapiens]                                 858   0.0  
gi|134244281 melanoma-associated antigen p97 isoform 1 precursor...   467   e-131
gi|16163666 melanoma-associated antigen p97 isoform 2 precursor ...   191   2e-48
gi|239755070 PREDICTED: similar to proprotein convertase subtili...    33   1.2  
gi|239749596 PREDICTED: hypothetical protein XP_002347099 [Homo ...    33   1.2  
gi|239743863 PREDICTED: hypothetical protein XP_002342982 [Homo ...    33   1.2  
gi|17318559 cyclin E1 isoform 1 [Homo sapiens]                         31   4.5  
gi|17318561 cyclin E1 isoform 2 [Homo sapiens]                         31   4.5  
gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens]         30   7.7  

>gi|54607120 lactotransferrin precursor [Homo sapiens]
          Length = 710

 Score = 1465 bits (3792), Expect = 0.0
 Identities = 710/710 (100%), Positives = 710/710 (100%)

Query: 1   MKLVFLVLLFLGALGLCLAGRRRSVQWCAVSQPEATKCFQWQRNMRKVRGPPVSCIKRDS 60
           MKLVFLVLLFLGALGLCLAGRRRSVQWCAVSQPEATKCFQWQRNMRKVRGPPVSCIKRDS
Sbjct: 1   MKLVFLVLLFLGALGLCLAGRRRSVQWCAVSQPEATKCFQWQRNMRKVRGPPVSCIKRDS 60

Query: 61  PIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKG 120
           PIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKG
Sbjct: 61  PIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKG 120

Query: 121 GSFQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGA 180
           GSFQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGA
Sbjct: 121 GSFQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGA 180

Query: 181 DKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDE 240
           DKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDE
Sbjct: 181 DKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDE 240

Query: 241 AERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKD 300
           AERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKD
Sbjct: 241 AERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKD 300

Query: 301 KSPKFQLFGSPSGQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSEEEVAAR 360
           KSPKFQLFGSPSGQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSEEEVAAR
Sbjct: 301 KSPKFQLFGSPSGQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSEEEVAAR 360

Query: 361 RARVVWCAVGEQELRKCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYT 420
           RARVVWCAVGEQELRKCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYT
Sbjct: 361 RARVVWCAVGEQELRKCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYT 420

Query: 421 AGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHT 480
           AGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHT
Sbjct: 421 AGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHT 480

Query: 481 AVDRTAGWNIPMGLLFNQTGSCKFDEYFSQSCAPGSDPRSNLCALCIGDEQGENKCVPNS 540
           AVDRTAGWNIPMGLLFNQTGSCKFDEYFSQSCAPGSDPRSNLCALCIGDEQGENKCVPNS
Sbjct: 481 AVDRTAGWNIPMGLLFNQTGSCKFDEYFSQSCAPGSDPRSNLCALCIGDEQGENKCVPNS 540

Query: 541 NERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRK 600
           NERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRK
Sbjct: 541 NERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRK 600

Query: 601 PVTEARSCHLAMAPNHAVVSRMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSETKNL 660
           PVTEARSCHLAMAPNHAVVSRMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSETKNL
Sbjct: 601 PVTEARSCHLAMAPNHAVVSRMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSETKNL 660

Query: 661 LFNDNTECLARLHGKTTYEKYLGPQYVAGITNLKKCSTSPLLEACEFLRK 710
           LFNDNTECLARLHGKTTYEKYLGPQYVAGITNLKKCSTSPLLEACEFLRK
Sbjct: 661 LFNDNTECLARLHGKTTYEKYLGPQYVAGITNLKKCSTSPLLEACEFLRK 710


>gi|4557871 transferrin [Homo sapiens]
          Length = 698

 Score =  858 bits (2216), Expect = 0.0
 Identities = 430/714 (60%), Positives = 520/714 (72%), Gaps = 22/714 (3%)

Query: 1   MKLVFLVLLFLGALGLCLAGRRRSVQWCAVSQPEATKCFQWQRNMRKV---RGPPVSCIK 57
           M+L    LL    LGLCLA   ++V+WCAVS+ EATKC  ++ +M+ V    GP V+C+K
Sbjct: 1   MRLAVGALLVCAVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVK 60

Query: 58  RDSPIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVV 117
           + S + CI+AIA N ADAVTLD G +Y+A LAP  L+PV AE YG++  P+T YYAVAVV
Sbjct: 61  KASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVV 120

Query: 118 KKGGSFQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCV 177
           KK   FQ+N+L+G KSCHTGL R+AGWN+PIG L  + +   P +P+E AVA FFS SC 
Sbjct: 121 KKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLL--YCDLPEPRKPLEKAVANFFSGSCA 178

Query: 178 PGADKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDL 237
           P AD   FP LC+LC G     C  S+   YF YSGAFKCL+DGAGDVAF++ ST+FE+L
Sbjct: 179 PCADGTDFPQLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENL 233

Query: 238 SDEAERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKF 297
           +++A+RD+YELLC DNTRKPVD++KDCHLA+VPSH VVARS+ GKED IW LL QAQE F
Sbjct: 234 ANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHF 293

Query: 298 GKDKSPKFQLFGSPSGQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSE--E 355
           GKDKS +FQLF SP G KDLLFKDSA GF +VPPR+D+ +YLG  Y TAI+NLR+    E
Sbjct: 294 GKDKSKEFQLFSSPHG-KDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTCPE 352

Query: 356 EVAARRARVVWCAVGEQELRKCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDG 415
                   V WCA+   E  KC++WS  S G + C SA TTEDCIA ++ GEADAMSLDG
Sbjct: 353 APTDECKPVKWCALSHHERLKCDEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDG 412

Query: 416 GYVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGK 475
           G+VY AGKCGLVPVLAENY          NC D P  GY AVAVV++S + LTW+++KGK
Sbjct: 413 GFVYIAGKCGLVPVLAENYNKSD------NCEDTPEAGYFAVAVVKKSASDLTWDNLKGK 466

Query: 476 KSCHTAVDRTAGWNIPMGLLFNQTGSCKFDEYFSQSCAPGSDPRSNLCALCIGDEQGENK 535
           KSCHTAV RTAGWNIPMGLL+N+   C+FDE+FS+ CAPGS   S+LC LC+G   G N 
Sbjct: 467 KSCHTAVGRTAGWNIPMGLLYNKINHCRFDEFFSEGCAPGSKKDSSLCKLCMGS--GLNL 524

Query: 536 CVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCL 595
           C PN+ E YYGYTGAFRCL E  GDVAFVK  TV QNT G N + WAK+L   D+ LLCL
Sbjct: 525 CEPNNKEGYYGYTGAFRCLVEK-GDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCL 583

Query: 596 DGKRKPVTEARSCHLAMAPNHAVVSRMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQS 655
           DG RKPV E  +CHLA APNHAVV+R DK   + ++L  QQ  FG N +DC   FCLF+S
Sbjct: 584 DGTRKPVEEYANCHLARAPNHAVVTRKDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRS 643

Query: 656 ETKNLLFNDNTECLARLHGKTTYEKYLGPQYVAGITNLKKCSTSPLLEACEFLR 709
           ETK+LLF D+T CLA+LH + TYEKYLG +YV  + NL+KCSTS LLEAC F R
Sbjct: 644 ETKDLLFRDDTVCLAKLHDRNTYEKYLGEEYVKAVGNLRKCSTSSLLEACTFRR 697


>gi|134244281 melanoma-associated antigen p97 isoform 1 precursor
           [Homo sapiens]
          Length = 738

 Score =  467 bits (1201), Expect = e-131
 Identities = 292/727 (40%), Positives = 409/727 (56%), Gaps = 63/727 (8%)

Query: 12  GALGLCLAGRR----RSVQWCAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQ 66
           GAL L LA R       V+WCA S PE  KC       R+    P + C++  S   C+Q
Sbjct: 6   GALWLLLALRTVLGGMEVRWCATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQ 65

Query: 67  AIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGSFQLN 126
            IA   ADA+TLDGG IYEAG   + L+PV  EVY  +++  T YYAVAVV++     ++
Sbjct: 66  LIAAQEADAITLDGGAIYEAG-KEHGLKPVVGEVY--DQEVGTSYYAVAVVRRSSHVTID 122

Query: 127 ELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFP 186
            L+G+KSCHTG+ RT GWNVP+G L      +     +  AV+ +F  SCVPGA +  + 
Sbjct: 123 TLKGVKSCHTGINRTVGWNVPVGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYS 182

Query: 187 -NLCRLCAG--TGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAE- 242
            +LCRLC G  +GE  C  S  E Y+ YSGAF+CL +GAGDVAF++ STV E+   +   
Sbjct: 183 ESLCRLCRGDSSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLP 242

Query: 243 -------RDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQE 295
                    ++ELLC D +R  V +++ CHLARVP+HAVV R+ +     I+ LL + Q 
Sbjct: 243 SWGQALLSQDFELLCRDGSRADVTEWRQCHLARVPAHAVVVRA-DTDGGLIFRLLNEGQR 301

Query: 296 KFGKDKSPKFQLFGSPS-GQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSE 354
            F  + S  FQ+F S + GQKDLLFKDS      +  +     +LG  Y  A++ L    
Sbjct: 302 LFSHEGS-SFQMFSSEAYGQKDLLFKDSTSELVPIATQTYEA-WLGHEYLHAMKGLLCDP 359

Query: 355 EEVAARRARVVWCAVGEQELRKCNQWSGLS-----EGSVTCSSASTTEDCIALVLKGEAD 409
             +      + WC +   E++KC   +        +  + C SA + + C+  +   + D
Sbjct: 360 NRLPPY---LRWCVLSTPEIQKCGDMAVAFRRQRLKPEIQCVSAKSPQHCMERIQAEQVD 416

Query: 410 AMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRR-SDTSL 467
           A++L G  +YTAGK  GLVP   E+Y  + SS+            Y  VAVVRR S  + 
Sbjct: 417 AVTLSGEDIYTAGKTYGLVPAAGEHYAPEDSSN-----------SYYVVAVVRRDSSHAF 465

Query: 468 TWNSVKGKKSCHTAVDRTAGWNIPMGLL----FNQTGSCKF----DEYFSQSCAPGSDPR 519
           T + ++GK+SCH      AGW++P+G L    F +   C       E+F+ SC P ++P+
Sbjct: 466 TLDELRGKRSCHAGFGSPAGWDVPVGALIQRGFIRPKDCDVLTAVSEFFNASCVPVNNPK 525

Query: 520 ---SNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGN 576
              S+LCALC+GDEQG NKCV NS ERYYGY GAFRCL ENAGDVAFV+  TV  NT+G+
Sbjct: 526 NYPSSLCALCVGDEQGRNKCVGNSQERYYGYRGAFRCLVENAGDVAFVRHTTVFDNTNGH 585

Query: 577 NNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVSRMD-KVERLKQVLLHQ 635
           N+E WA +L+  D+ LLC +G R  V++  +C+LA  P HAV+ R D  +  +  +L   
Sbjct: 586 NSEPWAAELRSEDYELLCPNGARAEVSQFAACNLAQIPPHAVMVRPDTNIFTVYGLLDKA 645

Query: 636 QAKFGRNGSDCPDKFCLFQSET---KNLLFNDNTECLARLHGKTTYEKYLGPQYVAGITN 692
           Q  FG + +   + F +F S     ++LLF D T     +  KTTY  +LG  YVA +  
Sbjct: 646 QDLFGDDHN--KNGFKMFDSSNYHGQDLLFKDATVRAVPVGEKTTYRGWLGLDYVAALEG 703

Query: 693 L--KKCS 697
           +  ++CS
Sbjct: 704 MSSQQCS 710



 Score =  220 bits (561), Expect = 3e-57
 Identities = 139/357 (38%), Positives = 199/357 (55%), Gaps = 25/357 (7%)

Query: 25  VQWCAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFI 83
           ++WC +S PE  KC       R+ R  P + C+   SP  C++ I   + DAVTL G  I
Sbjct: 366 LRWCVLSTPEIQKCGDMAVAFRRQRLKPEIQCVSAKSPQHCMERIQAEQVDAVTLSGEDI 425

Query: 84  YEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGS--FQLNELQGLKSCHTGLRRT 141
           Y AG   Y L P A E Y  E    + YY VAVV++  S  F L+EL+G +SCH G    
Sbjct: 426 YTAGKT-YGLVPAAGEHYAPEDSSNS-YYVVAVVRRDSSHAFTLDELRGKRSCHAGFGSP 483

Query: 142 AGWNVPIGTL--RPFLNWTGPPE-PIEAAVARFFSASCVPGADKGQFPN-LCRLCAGT-- 195
           AGW+VP+G L  R F+    P +  +  AV+ FF+ASCVP  +   +P+ LC LC G   
Sbjct: 484 AGWDVPVGALIQRGFIR---PKDCDVLTAVSEFFNASCVPVNNPKNYPSSLCALCVGDEQ 540

Query: 196 GENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSD--------EAERDEYE 247
           G NKC  +SQE Y+ Y GAF+CL + AGDVAF+R +TVF++ +         E   ++YE
Sbjct: 541 GRNKCVGNSQERYYGYRGAFRCLVENAGDVAFVRHTTVFDNTNGHNSEPWAAELRSEDYE 600

Query: 248 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK-FQ 306
           LLCP+  R  V +F  C+LA++P HAV+ R  +     ++ LL +AQ+ FG D +   F+
Sbjct: 601 LLCPNGARAEVSQFAACNLAQIPPHAVMVRP-DTNIFTVYGLLDKAQDLFGDDHNKNGFK 659

Query: 307 LFGSPSGQ-KDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSEEEVAARRA 362
           +F S +   +DLLFKD+ +    V  +     +LG  Y  A++ +   +   AA  A
Sbjct: 660 MFDSSNYHGQDLLFKDATVRAVPVGEKTTYRGWLGLDYVAALEGMSSQQCSGAAAPA 716


>gi|16163666 melanoma-associated antigen p97 isoform 2 precursor
           [Homo sapiens]
          Length = 302

 Score =  191 bits (486), Expect = 2e-48
 Identities = 121/315 (38%), Positives = 171/315 (54%), Gaps = 27/315 (8%)

Query: 12  GALGLCLAGRR----RSVQWCAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQ 66
           GAL L LA R       V+WCA S PE  KC       R+    P + C++  S   C+Q
Sbjct: 6   GALWLLLALRTVLGGMEVRWCATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQ 65

Query: 67  AIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGSFQLN 126
            IA   ADA+TLDGG IYEAG   + L+PV  EVY  +++  T YYAVAVV++     ++
Sbjct: 66  LIAAQEADAITLDGGAIYEAG-KEHGLKPVVGEVY--DQEVGTSYYAVAVVRRSSHVTID 122

Query: 127 ELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGADKGQF- 185
            L+G+KSCHTG+ RT GWNVP+G L      +     +  AV+ +F  SCVPGA +  + 
Sbjct: 123 TLKGVKSCHTGINRTVGWNVPVGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYS 182

Query: 186 PNLCRLCAG--TGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAER 243
            +LCRLC G  +GE  C  S  E Y+ YSGAF+CL +GAGDVAF++ STV E+  +   R
Sbjct: 183 ESLCRLCRGDSSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDESPSR 242

Query: 244 DEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSP 303
            +          +  ++  +C     P+H    R++       W   + A     +D+S 
Sbjct: 243 RQ-------TWTRSEEEEGEC-----PAHEEARRTMRSSAGQAW---KWAPVHRPQDESD 287

Query: 304 KFQLFGSPSGQKDLL 318
           K + FG  +  +D+L
Sbjct: 288 KGE-FGKRAKSRDML 301



 Score =  169 bits (428), Expect = 8e-42
 Identities = 100/239 (41%), Positives = 132/239 (55%), Gaps = 32/239 (13%)

Query: 364 VVWCAVGEQELRKCNQWSGLS-----EGSVTCSSASTTEDCIALVLKGEADAMSLDGGYV 418
           V WCA  + E  KC   S        + S+ C   ++ + C+ L+   EADA++LDGG +
Sbjct: 23  VRWCATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAI 82

Query: 419 YTAGK-CGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKS 477
           Y AGK  GL PV+ E Y  +  +             Y AVAVVRRS + +T +++KG KS
Sbjct: 83  YEAGKEHGLKPVVGEVYDQEVGTS------------YYAVAVVRRS-SHVTIDTLKGVKS 129

Query: 478 CHTAVDRTAGWNIPMGLLFNQ----TGSCKF----DEYFSQSCAPGSDPRS---NLCALC 526
           CHT ++RT GWN+P+G L          C       +YF  SC PG+   S   +LC LC
Sbjct: 130 CHTGINRTVGWNVPVGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSESLCRLC 189

Query: 527 IGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTD--GNNNEAWAK 583
            GD  GE  C  +  ERYY Y+GAFRCLAE AGDVAFVK  TVL+NTD   +  + W +
Sbjct: 190 RGDSSGEGVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDESPSRRQTWTR 248


>gi|239755070 PREDICTED: similar to proprotein convertase
           subtilisin/kexin type 5 [Homo sapiens]
          Length = 853

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 27/95 (28%), Positives = 34/95 (35%), Gaps = 17/95 (17%)

Query: 476 KSCHTAVDRTAGWNIPMGLLFNQTGSCKFDEYFSQS-----CAPGSDPRSNLCALCIGDE 530
           KSC T            GL+ N  GSC  +E  S S      APG  P    C  C+G  
Sbjct: 416 KSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPA 475

Query: 531 QGE------------NKCVPNSNERYYGYTGAFRC 553
           + +              CV +  E YY    + RC
Sbjct: 476 EDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRC 510


>gi|239749596 PREDICTED: hypothetical protein XP_002347099 [Homo
           sapiens]
          Length = 853

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 27/95 (28%), Positives = 34/95 (35%), Gaps = 17/95 (17%)

Query: 476 KSCHTAVDRTAGWNIPMGLLFNQTGSCKFDEYFSQS-----CAPGSDPRSNLCALCIGDE 530
           KSC T            GL+ N  GSC  +E  S S      APG  P    C  C+G  
Sbjct: 416 KSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPA 475

Query: 531 QGE------------NKCVPNSNERYYGYTGAFRC 553
           + +              CV +  E YY    + RC
Sbjct: 476 EDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRC 510


>gi|239743863 PREDICTED: hypothetical protein XP_002342982 [Homo
           sapiens]
          Length = 853

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 27/95 (28%), Positives = 34/95 (35%), Gaps = 17/95 (17%)

Query: 476 KSCHTAVDRTAGWNIPMGLLFNQTGSCKFDEYFSQS-----CAPGSDPRSNLCALCIGDE 530
           KSC T            GL+ N  GSC  +E  S S      APG  P    C  C+G  
Sbjct: 416 KSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPA 475

Query: 531 QGE------------NKCVPNSNERYYGYTGAFRC 553
           + +              CV +  E YY    + RC
Sbjct: 476 EDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRC 510


>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
          Length = 410

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 32/144 (22%), Positives = 60/144 (41%), Gaps = 15/144 (10%)

Query: 376 KCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGG---YVYTAGKCGLVPVLAE 432
           K +Q++ +++G+ +     T E  I   LK     +++      Y+  A    L  VL  
Sbjct: 209 KLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLP 268

Query: 433 NYKSQ---QSSDP------DPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVD 483
            Y  Q   Q ++       D +C++ P  G LA + +    +S     V G + C   ++
Sbjct: 269 QYPQQIFIQIAELLDLCVLDVDCLEFPY-GILAASALYHFSSSELMQKVSGYQWCD--IE 325

Query: 484 RTAGWNIPMGLLFNQTGSCKFDEY 507
               W +P  ++  +TGS K   +
Sbjct: 326 NCVKWMVPFAMVIRETGSSKLKHF 349


>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
          Length = 395

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 32/144 (22%), Positives = 60/144 (41%), Gaps = 15/144 (10%)

Query: 376 KCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGG---YVYTAGKCGLVPVLAE 432
           K +Q++ +++G+ +     T E  I   LK     +++      Y+  A    L  VL  
Sbjct: 194 KLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLP 253

Query: 433 NYKSQ---QSSDP------DPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVD 483
            Y  Q   Q ++       D +C++ P  G LA + +    +S     V G + C   ++
Sbjct: 254 QYPQQIFIQIAELLDLCVLDVDCLEFPY-GILAASALYHFSSSELMQKVSGYQWCD--IE 310

Query: 484 RTAGWNIPMGLLFNQTGSCKFDEY 507
               W +P  ++  +TGS K   +
Sbjct: 311 NCVKWMVPFAMVIRETGSSKLKHF 334


>gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens]
          Length = 1121

 Score = 30.0 bits (66), Expect = 7.7
 Identities = 12/39 (30%), Positives = 24/39 (61%)

Query: 410 AMSLDGGYVYTAGKCGLVPVLAENYKSQQSSDPDPNCVD 448
           A+SL+  ++++   CG++ VL ENY+  +    D  C++
Sbjct: 695 ALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLE 733


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,768,472
Number of Sequences: 37866
Number of extensions: 1412802
Number of successful extensions: 2797
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2722
Number of HSP's gapped (non-prelim): 12
length of query: 710
length of database: 18,247,518
effective HSP length: 109
effective length of query: 601
effective length of database: 14,120,124
effective search space: 8486194524
effective search space used: 8486194524
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.