Search of human proteins with 54607080

Search of human proteins with 54607080

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
         (417 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s...   854   0.0  
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]             447   e-125
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]   365   e-101
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ...   344   1e-94
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]               343   1e-94
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]          332   3e-91
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa...   329   3e-90
gi|27436871 carboxypeptidase O [Homo sapiens]                         306   2e-83
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]             295   5e-80
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]             295   5e-80
gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]      240   2e-63
gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]             201   1e-51
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]             149   6e-36
gi|22202611 carboxypeptidase D precursor [Homo sapiens]                52   1e-06
gi|53832021 carboxypeptidase M precursor [Homo sapiens]                46   7e-05
gi|38327526 carboxypeptidase M precursor [Homo sapiens]                46   7e-05
gi|6631081 carboxypeptidase M precursor [Homo sapiens]                 46   7e-05
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]       37   0.043
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap...    36   0.074
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap...    32   1.4  
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]        30   4.1  
gi|9558749 elongation factor-2 kinase [Homo sapiens]                   30   5.3  
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]    29   9.0  
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]    29   9.0  
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]    29   9.0  

>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
           sapiens]
          Length = 417

 Score =  854 bits (2206), Expect = 0.0
 Identities = 417/417 (100%), Positives = 417/417 (100%)

Query: 1   MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ 60
           MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ
Sbjct: 1   MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ 60

Query: 61  IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYN 120
           IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYN
Sbjct: 61  IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYN 120

Query: 121 KWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREW 180
           KWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREW
Sbjct: 121 KWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREW 180

Query: 181 ISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTH 240
           ISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTH
Sbjct: 181 ISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTH 240

Query: 241 TGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAY 300
           TGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAY
Sbjct: 241 TGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAY 300

Query: 301 LTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAG 360
           LTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAG
Sbjct: 301 LTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAG 360

Query: 361 GSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY 417
           GSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY
Sbjct: 361 GSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY 417


>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
          Length = 417

 Score =  447 bits (1149), Expect = e-125
 Identities = 204/412 (49%), Positives = 291/412 (70%), Gaps = 6/412 (1%)

Query: 5   LVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPH 64
           L+  T+A+A        F+ EKVFRV  +DE   +II++LA T ++DFW P +   +  +
Sbjct: 9   LIATTLAIAPVR-----FDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAAN 63

Query: 65  STVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATG-HSYEKYNKWE 123
             VDFRV  +++  +++ L QN++ Y++LI +L+  +E QFD +    G HSY KYN WE
Sbjct: 64  MMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNNWE 123

Query: 124 TIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISP 183
            I AWT+++  + P ++SR  IG+T E   +Y+LK+G+  + + AIF DCG HAREW+SP
Sbjct: 124 KIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSP 183

Query: 184 AFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGS 243
           AFCQWFV +A +TYGR   +T+LLD+++FY+LPV N+DGYI++WTK+R WRK RS +  S
Sbjct: 184 AFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNS 243

Query: 244 SCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTI 303
            CIGTD NRNF+A W  I  + +PC + Y G A ESEKETKA+ +FIR+ L+ IK Y+T 
Sbjct: 244 KCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITF 303

Query: 304 HSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSD 363
           HSYSQM+++PY Y  KL  N+ +L  +AK     L++ + T+Y YGP  +TIYP +G S 
Sbjct: 304 HSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSL 363

Query: 364 DWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEH 415
           DWAYD GI+++F FELRD G++GFLLPES+I+ TC ET LA+K++A Y+L+H
Sbjct: 364 DWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKH 415


>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
          Length = 437

 Score =  365 bits (937), Expect = e-101
 Identities = 171/418 (40%), Positives = 261/418 (62%), Gaps = 5/418 (1%)

Query: 2   LALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQI 61
           L  L L  +    +H     + G+KV R   + E     +++++   ++D W+P S++ +
Sbjct: 17  LCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYV 76

Query: 62  KPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFD-----SRVRATGHSY 116
              +  D  +    +  +   L++  +QYKVLI +L+  +E         +R   +G++Y
Sbjct: 77  SEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNY 136

Query: 117 EKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFH 176
           E Y+  E I+ W   +   +  LI    IG ++EGR++++LK+G+  + K A+++DCG H
Sbjct: 137 EVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIH 196

Query: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236
           AREWI PAFCQWFV+EA+ TY  +  + ++L+ L FY++PV N+DGY ++WT  RFWRKT
Sbjct: 197 AREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKT 256

Query: 237 RSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSS 296
           RS ++   C G D NRN+   WC+ GAS +PCD+TYCGP  ESE E KA+A+F+R     
Sbjct: 257 RSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKH 316

Query: 297 IKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIY 356
           I+AYL+ H+Y+QM++YPYSY Y    N   + + A   V  L S++G +Y YGP +TT+Y
Sbjct: 317 IRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLY 376

Query: 357 PAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLE 414
            ++G S DWAY  GI Y+F FELRDTG +GFLLPE  I+ TC ET LA+K +  ++L+
Sbjct: 377 VSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLK 434


>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
           [Homo sapiens]
          Length = 423

 Score =  344 bits (882), Expect = 1e-94
 Identities = 175/422 (41%), Positives = 258/422 (61%), Gaps = 7/422 (1%)

Query: 1   MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ 60
           + +L VLV + L    H    F+  +V          + +++ L +T +I  W+P +   
Sbjct: 3   LCSLAVLVPIVLFCEQHVFA-FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADL 61

Query: 61  IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRV---RATGHSYE 117
           I     V F V A D   V+  L  + +   VL++++ ++++ Q  +     RA+   YE
Sbjct: 62  IVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYE 121

Query: 118 KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV-GKAGQNKPAIFMDCGFH 176
           +Y+    I +W + +   +P ++++  IG++FE   +Y+LKV GK    K AI++DCG H
Sbjct: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIH 181

Query: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236
           AREWISPAFC WF+    + YG   Q T LL  +DFYV+PV+N+DGY Y+W K+R WRK 
Sbjct: 182 AREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKN 241

Query: 237 RSTHTGSSCIGTDPNRNF-DAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLS 295
           RS +  + CIGTD NRNF    WCE GAS + C ETYCG   ESE E KA+A F+R  ++
Sbjct: 242 RSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNIN 301

Query: 296 SIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKEL-ASLHGTKYTYGPGATT 354
            IKAY+++HSYSQ +++PYSY     +++ EL+ +A   V+ +  +   T+YT+G G+ T
Sbjct: 302 QIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSET 361

Query: 355 IYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLE 414
           +Y A GG DDW YD GI+YSFT ELRDTG YGFLLPE  I+ TC E F A+  +A +V+ 
Sbjct: 362 LYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIR 421

Query: 415 HL 416
           ++
Sbjct: 422 NV 423


>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
          Length = 419

 Score =  343 bits (881), Expect = 1e-94
 Identities = 181/421 (42%), Positives = 261/421 (61%), Gaps = 14/421 (3%)

Query: 6   VLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTT--QIDFWKPDSVTQIKP 63
           +LV   L  A  G E F G +V R++V DE  +  ++EL      Q+DFW+  +     P
Sbjct: 4   LLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPA----HP 59

Query: 64  HSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQ------FDSRVRATG-HSY 116
            S +D RV       V+  L+ + + Y+ +I +++++++ +      F SR R+T   +Y
Sbjct: 60  GSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNY 119

Query: 117 EKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFH 176
             Y+  E I  +   +  ENP L+S+  IG T+EGR IY+LK    G  +PAI++D G H
Sbjct: 120 ATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIH 179

Query: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236
           +REW++ A   WF ++  + YG++   T +LD LD ++  V N DG+ +T + +R WRKT
Sbjct: 180 SREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKT 239

Query: 237 RSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSS 296
           RS   GS CIG DPNRN+DAG+   GAS NPC ETY G  A SE E K++ DF+++   +
Sbjct: 240 RSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDH-GN 298

Query: 297 IKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIY 356
           IKA+++IHSYSQ+++YPY Y  +   +  EL+ L+KA V  LASL+GTK+ YG     IY
Sbjct: 299 IKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIY 358

Query: 357 PAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHL 416
            A+G + DW Y QGI+YSFTFELRDTGRYGFLLP SQI  T +ET+LA+  +  + L H 
Sbjct: 359 QASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHP 418

Query: 417 Y 417
           Y
Sbjct: 419 Y 419


>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
          Length = 421

 Score =  332 bits (852), Expect = 3e-91
 Identities = 173/423 (40%), Positives = 260/423 (61%), Gaps = 15/423 (3%)

Query: 5   LVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTT--QIDFWKPDSVTQIK 62
           ++ +   + S+  G E F G++V R+NV + + I+ + +L ++   +++FWK  S     
Sbjct: 4   ILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF--- 60

Query: 63  PHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGH-------S 115
            +  VD  V +      ++ L+   L+Y V I +L+ +++ + D      G        +
Sbjct: 61  -NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFN 119

Query: 116 YEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKA-GQNKPAIFMDCG 174
           Y  Y+  E I      +A + P L  R  IG +FE R +Y+LK     G  +PA++++ G
Sbjct: 120 YGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAG 179

Query: 175 FHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWR 234
            H+REWIS A   W  R+ V  Y R+  +T +L+K+D ++LPV N DGY+YT T++R WR
Sbjct: 180 IHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWR 239

Query: 235 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 294
           KTRS + GSSCIG DPNRN++A +   GAS NPC E Y GP A SE E K++ DFI+ K 
Sbjct: 240 KTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQ-KH 298

Query: 295 SSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATT 354
            + K ++ +HSYSQ+++YPY Y+ K   +  EL+ +A+   K LAS+ GT+Y  GP  TT
Sbjct: 299 GNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTT 358

Query: 355 IYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLE 414
           +YPA+G S DWAYD GI+++FTFELRDTG YGFLLP +QI  T EET+L +K +  +V +
Sbjct: 359 VYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRD 418

Query: 415 HLY 417
           +LY
Sbjct: 419 NLY 421


>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
           sapiens]
          Length = 419

 Score =  329 bits (843), Expect = 3e-90
 Identities = 172/425 (40%), Positives = 259/425 (60%), Gaps = 14/425 (3%)

Query: 1   MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTT--QIDFWKPDSV 58
           M   L+L   AL    +  E F G++V  +   +E  I  + +L +    Q+DFWK  + 
Sbjct: 1   MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTT 60

Query: 59  TQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDS------RVRAT 112
               P  T   RV   +   V+  L+   + Y ++I +++ +++ + +       R R+ 
Sbjct: 61  ----PGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSG 116

Query: 113 GHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMD 172
             ++  Y+  E I      +  E+P L+S+  IG++FE R + +LK    G +KPAI++D
Sbjct: 117 NFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGG-DKPAIWLD 175

Query: 173 CGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRF 232
            G HAREW++ A   W   + V  YG++  +T +LD LD ++LPV N DGY+++ TK+R 
Sbjct: 176 AGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRM 235

Query: 233 WRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRN 292
           WRKTRS  +GS C+G DPNRN+DAG+   GAS NPC ++Y GP+A SE E K++ DFI++
Sbjct: 236 WRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS 295

Query: 293 KLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGA 352
               +KA++T+HSYSQ++++PY Y     ++  EL+ +A+   + L SLHGTKY  GP  
Sbjct: 296 H-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPIC 354

Query: 353 TTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYV 412
           + IY A+GGS DW+YD GI+YSF FELRDTGRYGFLLP  QI  T EET+L +K +  +V
Sbjct: 355 SVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414

Query: 413 LEHLY 417
            +H Y
Sbjct: 415 RDHPY 419


>gi|27436871 carboxypeptidase O [Homo sapiens]
          Length = 374

 Score =  306 bits (785), Expect = 2e-83
 Identities = 141/293 (48%), Positives = 194/293 (66%), Gaps = 1/293 (0%)

Query: 114 HSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGK-AGQNKPAIFMD 172
           +SY  Y+    I  W ++++ +   ++++  +G T+E   +Y LK+ + +G  K  I+MD
Sbjct: 45  YSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMD 104

Query: 173 CGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRF 232
           CG HAREWI+PAFCQWFV+E ++ +     + +LL  LDFYVLPVLNIDGYIYTWT  R 
Sbjct: 105 CGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRL 164

Query: 233 WRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRN 292
           WRK+RS H   +C GTD NRNF+A WC IGASRN  D+T+CG    SE ETKA+A FI +
Sbjct: 165 WRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIES 224

Query: 293 KLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGA 352
           K   I  +LT+HSY Q+++ PY Y      N+ E+  + +     L + +GT Y  G  A
Sbjct: 225 KKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSA 284

Query: 353 TTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAI 405
             +Y ++G S DWA D GI +S+TFELRD+G YGF+LPE+QI+ TCEET  A+
Sbjct: 285 DILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAV 337


>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
          Length = 436

 Score =  295 bits (755), Expect = 5e-80
 Identities = 152/421 (36%), Positives = 250/421 (59%), Gaps = 14/421 (3%)

Query: 6   VLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTT--QIDFWKPDSVTQIKP 63
           +LV   + +A  G  +F G++V RV  +DE  ++++ +L      ++DFW+  +    +P
Sbjct: 21  LLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPA----RP 76

Query: 64  HSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRA-------TGHSY 116
              VD RV   +   ++  L+ + L Y ++I +++ +++ +  +  ++          SY
Sbjct: 77  SLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSY 136

Query: 117 EKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFH 176
             Y+  E I +W      E+  ++S+  IG +FE ++I +LK    G   PAI++D G H
Sbjct: 137 SSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIH 196

Query: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236
           +REWI+ A   W   + V  YG++  +T++L+ +D ++  V N DG+ +T + +R WRK 
Sbjct: 197 SREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKN 256

Query: 237 RSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSS 296
           +S   G  CIG D NRN+ +G+   G++ NPC ETY GP+ +SE E  A+ +FI     +
Sbjct: 257 KSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFI-TAHGN 315

Query: 297 IKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIY 356
            KA ++IHSYSQM++YPY    +   N  EL  LAK  V+ L  +HG +Y +G  +TT+Y
Sbjct: 316 FKALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLY 375

Query: 357 PAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHL 416
            A+G + DWAYD GI+Y+F+FELRDTG+YGFLLP +QI  T +ET++A++ +  + L H 
Sbjct: 376 VASGITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHP 435

Query: 417 Y 417
           Y
Sbjct: 436 Y 436


>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
          Length = 436

 Score =  295 bits (755), Expect = 5e-80
 Identities = 152/421 (36%), Positives = 250/421 (59%), Gaps = 14/421 (3%)

Query: 6   VLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTT--QIDFWKPDSVTQIKP 63
           +LV   + +A  G  +F G++V RV  +DE  ++++ +L      ++DFW+  +    +P
Sbjct: 21  LLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPA----RP 76

Query: 64  HSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRA-------TGHSY 116
              VD RV   +   ++  L+ + L Y ++I +++ +++ +  +  ++          SY
Sbjct: 77  SLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSY 136

Query: 117 EKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFH 176
             Y+  E I +W      E+  ++S+  IG +FE ++I +LK    G   PAI++D G H
Sbjct: 137 SSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIH 196

Query: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236
           +REWI+ A   W   + V  YG++  +T++L+ +D ++  V N DG+ +T + +R WRK 
Sbjct: 197 SREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKN 256

Query: 237 RSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSS 296
           +S   G  CIG D NRN+ +G+   G++ NPC ETY GP+ +SE E  A+ +FI     +
Sbjct: 257 KSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFI-TAHGN 315

Query: 297 IKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIY 356
            KA ++IHSYSQM++YPY    +   N  EL  LAK  V+ L  +HG +Y +G  +TT+Y
Sbjct: 316 FKALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLY 375

Query: 357 PAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHL 416
            A+G + DWAYD GI+Y+F+FELRDTG+YGFLLP +QI  T +ET++A++ +  + L H 
Sbjct: 376 VASGITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHP 435

Query: 417 Y 417
           Y
Sbjct: 436 Y 436


>gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]
          Length = 360

 Score =  240 bits (612), Expect = 2e-63
 Identities = 134/382 (35%), Positives = 205/382 (53%), Gaps = 44/382 (11%)

Query: 1   MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ 60
           + +L VLV + L    H    F+  +V          + +++ L +T +I  W+P +   
Sbjct: 3   LCSLAVLVPIVLFCEQHVFA-FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADL 61

Query: 61  IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRV---RATGHSYE 117
           I     V F V A D   V+  L  + +   VL++++ ++++ Q  +     RA+   YE
Sbjct: 62  IVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYE 121

Query: 118 KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV-GKAGQNKPAIFMDCGFH 176
           +Y+    I +W + +   +P ++++  IG++FE   +Y+LKV GK    K AI++DCG H
Sbjct: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIH 181

Query: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236
           AREWISPAFC WF+                                       +R WRK 
Sbjct: 182 AREWISPAFCLWFIGH-------------------------------------NRMWRKN 204

Query: 237 RSTHTGSSCIGTDPNRNFDAG-WCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLS 295
           RS +  + CIGTD NRNF +  WCE GAS + C ETYCG   ESE E KA+A F+R  ++
Sbjct: 205 RSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNIN 264

Query: 296 SIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKEL-ASLHGTKYTYGPGATT 354
            IKAY+++HSYSQ +++PYSY     +++ EL+ +A   V+ +  +   T+YT+G G+ T
Sbjct: 265 QIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSET 324

Query: 355 IYPAAGGSDDWAYDQGIRYSFT 376
           +Y A GG DDW YD GI+YS T
Sbjct: 325 LYLAPGGGDDWIYDLGIKYSVT 346


>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
          Length = 403

 Score =  201 bits (510), Expect = 1e-51
 Identities = 107/331 (32%), Positives = 185/331 (55%), Gaps = 14/331 (4%)

Query: 6   VLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTT--QIDFWKPDSVTQIKP 63
           +LV   + +A  G  +F G++V RV  +DE  ++++ +L      ++DFW+  +    +P
Sbjct: 21  LLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPA----RP 76

Query: 64  HSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRA-------TGHSY 116
              VD RV   +   ++  L+ + L Y ++I +++ +++ +  +  ++          SY
Sbjct: 77  SLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSY 136

Query: 117 EKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFH 176
             Y+  E I +W      E+  ++S+  IG +FE ++I +LK    G   PAI++D G H
Sbjct: 137 SSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIH 196

Query: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236
           +REWI+ A   W   + V  YG++  +T++L+ +D ++  V N DG+ +T + +R WRK 
Sbjct: 197 SREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKN 256

Query: 237 RSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSS 296
           +S   G  CIG D NRN+ +G+   G++ NPC ETY GP+ +SE E  A+ +FI     +
Sbjct: 257 KSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFI-TAHGN 315

Query: 297 IKAYLTIHSYSQMMIYPYSYAYKLGENNAEL 327
            KA ++IHSYSQM++YPY    +   N  EL
Sbjct: 316 FKALISIHSYSQMLMYPYGRLLEPVSNQREL 346


>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
          Length = 193

 Score =  149 bits (375), Expect = 6e-36
 Identities = 61/125 (48%), Positives = 91/125 (72%)

Query: 139 LISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYG 198
           LI    IG ++EGR++++LK+G+  + K A+++DCG HAREWI PAFCQWFV+EA+ TY 
Sbjct: 11  LIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYK 70

Query: 199 REIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGW 258
            +  + ++L+ L FY++PV N+DGY ++WT  RFWRKTRS ++   C G D NRN+   W
Sbjct: 71  SDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKW 130

Query: 259 CEIGA 263
           C++ +
Sbjct: 131 CDVSS 135



 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 32/57 (56%), Positives = 42/57 (73%)

Query: 358 AAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLE 414
           ++G S DWAY  GI Y+F FELRDTG +GFLLPE  I+ TC ET LA+K +  ++L+
Sbjct: 134 SSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLK 190


>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
          Length = 1380

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 69/362 (19%), Positives = 139/362 (38%), Gaps = 63/362 (17%)

Query: 39  NIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLR 98
           N++ +    T++DF    +VT + P +T    V    TV + N+L      Y+ +     
Sbjct: 444 NVVVKEGPATEVDFSLRPTVTSVIPDTTE--AVSTASTVAIPNILSGTSSSYQPI----- 496

Query: 99  NVVEAQFDSRVRATGHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLK 158
                    + +   H +     +  +E + ++ A E P +     +G + E R +Y+++
Sbjct: 497 ---------QPKDFHHHH-----FPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVME 542

Query: 159 V----GKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYV 214
           +    G     +P        H  E +        +    + +G + +VT+L+     ++
Sbjct: 543 ISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHL 602

Query: 215 LPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCG 274
           +P +N DGY           +        S IG + + NFD        +RN  D+ +  
Sbjct: 603 MPSMNPDGY-----------EKSQEGDSISVIGRNNSNNFD-------LNRNFPDQ-FVQ 643

Query: 275 PAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYS------YAYKLGENNAELN 328
               ++ ET A+  ++++    + A   +H  S ++ YP+         Y    ++A   
Sbjct: 644 ITDPTQPETIAVMSWMKSYPFVLSA--NLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQ 701

Query: 329 ALAKATVKELASLHGTK----------YTYG-PGATTIYPAAGGSDDWAYDQGIRYSFTF 377
            +A +  KE + +   +          + +G     + Y   GG  DW Y Q   +  T 
Sbjct: 702 QIALSYSKENSQMFQGRPCKNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTI 761

Query: 378 EL 379
           EL
Sbjct: 762 EL 763



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 64/289 (22%), Positives = 109/289 (37%), Gaps = 55/289 (19%)

Query: 116 YEKYNKWETIEAWTQQVATEN-PALISRSVIGTTFEGRAIYLLKV----------GKAGQ 164
           +++Y   E +E+  ++ A    P L     IG + EGR +++L++          G AG 
Sbjct: 55  FDRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGP 114

Query: 165 N-------------KPAIFMDCGFHAREWISPAFCQWFVREAVRTYGR-EIQVTELLDKL 210
           +             +P + +    H  E +S     +  RE    Y R + ++  LL+  
Sbjct: 115 DAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTT 174

Query: 211 DFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTG------SSCIGTDPNRNFDAGWCEIGAS 264
           D Y+LP LN DG+           + R    G      S   G D +R  D        +
Sbjct: 175 DVYLLPSLNPDGF----------ERAREGDCGFGDGGPSGASGRDNSRGRD-------LN 217

Query: 265 RNPCDETYCG--PAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGE 322
           R+  D+   G  PA +   E +AL ++IR     +     +H  S +  YP+  + +   
Sbjct: 218 RSFPDQFSTGEPPALDEVPEVRALIEWIRRNKFVLSG--NLHGGSVVASYPFDDSPEHKA 275

Query: 323 NNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGI 371
                        K LA  + + +   P   T  P   G +D  +  GI
Sbjct: 276 TGIYSKTSDDEVFKYLAKAYASNH---PIMKTGEPHCPGDEDETFKDGI 321



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 48/233 (20%), Positives = 88/233 (37%), Gaps = 38/233 (16%)

Query: 118  KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGK----AGQNKPAIFMDC 173
            +Y+ ++ +  + + +    P + + + +G + E R I+ L++      +   +P I    
Sbjct: 932  RYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVA 991

Query: 174  GFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFW 233
            G H    +               Y +   VT+L+D+    ++P LN DG           
Sbjct: 992  GIHGNAPVGTELLLALAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDG----------- 1040

Query: 234  RKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNK 293
            R+       +S IG    R  D             D  +   A  S+ ETKA+ + +  K
Sbjct: 1041 RERAQEKDCTSKIGQTNARGKD------------LDTDFTNNA--SQPETKAIIENLIQK 1086

Query: 294  LSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKY 346
                   + +   S ++ YPY    +  EN        K T+K LASL+   +
Sbjct: 1087 -QDFSLSVALDGGSMLVTYPYDKPVQTVEN--------KETLKHLASLYANNH 1130


>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 56/282 (19%), Positives = 107/282 (37%), Gaps = 42/282 (14%)

Query: 119 YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDCG 174
           Y++ E +EA+ + VA    ++     IG + +GR +++L VG+  +      P       
Sbjct: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81

Query: 175 FHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWR 234
            H  E +        +   V + G++ ++T L++    +++P +N DG+        ++ 
Sbjct: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141

Query: 235 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 294
             R  +        D NRNF   +     SR P              ET A+  +++ + 
Sbjct: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182

Query: 295 SSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH--- 342
             + A   +H  + +  YP+          Y+  L  ++     LA        ++    
Sbjct: 183 FVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240

Query: 343 --GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 379
               K  +  G T   + YP  GG  D+ Y     +  T EL
Sbjct: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282


>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 56/282 (19%), Positives = 107/282 (37%), Gaps = 42/282 (14%)

Query: 119 YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDCG 174
           Y++ E +EA+ + VA    ++     IG + +GR +++L VG+  +      P       
Sbjct: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81

Query: 175 FHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWR 234
            H  E +        +   V + G++ ++T L++    +++P +N DG+        ++ 
Sbjct: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141

Query: 235 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 294
             R  +        D NRNF   +     SR P              ET A+  +++ + 
Sbjct: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182

Query: 295 SSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH--- 342
             + A   +H  + +  YP+          Y+  L  ++     LA        ++    
Sbjct: 183 FVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240

Query: 343 --GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 379
               K  +  G T   + YP  GG  D+ Y     +  T EL
Sbjct: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282


>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
          Length = 443

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 56/282 (19%), Positives = 107/282 (37%), Gaps = 42/282 (14%)

Query: 119 YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDCG 174
           Y++ E +EA+ + VA    ++     IG + +GR +++L VG+  +      P       
Sbjct: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81

Query: 175 FHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWR 234
            H  E +        +   V + G++ ++T L++    +++P +N DG+        ++ 
Sbjct: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141

Query: 235 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 294
             R  +        D NRNF   +     SR P              ET A+  +++ + 
Sbjct: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182

Query: 295 SSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH--- 342
             + A   +H  + +  YP+          Y+  L  ++     LA        ++    
Sbjct: 183 FVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240

Query: 343 --GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 379
               K  +  G T   + YP  GG  D+ Y     +  T EL
Sbjct: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282


>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
          Length = 734

 Score = 36.6 bits (83), Expect = 0.043
 Identities = 27/114 (23%), Positives = 56/114 (49%), Gaps = 11/114 (9%)

Query: 118 KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVG-KAGQNK---PAIFMDC 173
           +++ ++ +    +QV  + P +     IG +++G  +Y++++  K G+++   P +    
Sbjct: 298 QHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVA 357

Query: 174 GFHAREWISPAFC----QWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGY 223
           G H  E +         Q+   E +R   R   VT LL ++  ++LP +N DGY
Sbjct: 358 GMHGNEALGRELLLLLMQFLCHEFLRGNPR---VTRLLSEMRIHLLPSMNPDGY 408


>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
           sapiens]
          Length = 756

 Score = 35.8 bits (81), Expect = 0.074
 Identities = 30/118 (25%), Positives = 50/118 (42%), Gaps = 13/118 (11%)

Query: 145 IGTTFEGRAIYLLKV----GKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTY-GR 199
           IG + +G  +Y +++    G+    +P      G H  E +        V+   + Y  R
Sbjct: 344 IGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLAR 403

Query: 200 EIQVTELLDKLDFYVLPVLNIDGYIYTW---TKSRFWRKTRSTHTGSSCIGTDPNRNF 254
             ++  L+++   +VLP LN DGY   +   ++   W   R TH      G D N NF
Sbjct: 404 NARIVHLVEETRIHVLPSLNPDGYEKAYEGGSELGGWSLGRWTHD-----GIDINNNF 456


>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
           sapiens]
          Length = 458

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 51/251 (20%), Positives = 95/251 (37%), Gaps = 28/251 (11%)

Query: 118 KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV----GKAGQNKPAIFMDC 173
           ++++++ +     +V  E P +     IG + EGR +Y+L+     G     +P +    
Sbjct: 24  RHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVG 83

Query: 174 GFHAREWISPAF---CQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKS 230
             H  E +          F+ E  R   R  ++ +L+     ++LP +N DGY     + 
Sbjct: 84  NMHGNEALGRELMLQLSEFLCEEFR--NRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQG 141

Query: 231 RFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGP----------AAESE 280
               K       ++  G D NRNF      I       +E Y GP           ++ E
Sbjct: 142 P--NKPGYLVGRNNANGVDLNRNFPDLNTYI-----YYNEKYGGPNHHLPLPDNWKSQVE 194

Query: 281 KETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELAS 340
            ET+A+  ++ +    + A   +H  + +  YPY  +++         A       +L  
Sbjct: 195 PETRAVIRWMHSFNFVLSA--NLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQ 252

Query: 341 LHGTKYTYGPG 351
                Y+Y  G
Sbjct: 253 KLAKVYSYAHG 263


>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
          Length = 911

 Score = 30.0 bits (66), Expect = 4.1
 Identities = 14/38 (36%), Positives = 24/38 (63%)

Query: 57  SVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLI 94
           ++ Q   H TV+ + K    +T E VLK+N +QY+++I
Sbjct: 142 TMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVI 179


>gi|9558749 elongation factor-2 kinase [Homo sapiens]
          Length = 725

 Score = 29.6 bits (65), Expect = 5.3
 Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 3/52 (5%)

Query: 155 YLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQ-WFVREAVRTYGREIQVTE 205
           YLLK  +AG  +  I +   F + + +SP  CQ W   EA+  Y   +++T+
Sbjct: 600 YLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWL--EALHWYNTALEMTD 649


>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
          Length = 828

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 133 ATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAI---FMDCGFHAREWISPAFCQWF 189
           A E   L +R + G    G   Y+    +A  N P +   F+DCG  AR    PA C+ +
Sbjct: 173 ADEEDELRARGLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAICKSY 232

Query: 190 VR 191
           ++
Sbjct: 233 LK 234


>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
          Length = 942

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 133 ATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAI---FMDCGFHAREWISPAFCQWF 189
           A E   L +R + G    G   Y+    +A  N P +   F+DCG  AR    PA C+ +
Sbjct: 173 ADEEDELRARGLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAICKSY 232

Query: 190 VR 191
           ++
Sbjct: 233 LK 234


>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
          Length = 911

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 133 ATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAI---FMDCGFHAREWISPAFCQWF 189
           A E   L +R + G    G   Y+    +A  N P +   F+DCG  AR    PA C+ +
Sbjct: 142 ADEEDELRARGLTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDKKPAICKSY 201

Query: 190 VR 191
           ++
Sbjct: 202 LK 203


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,946,214
Number of Sequences: 37866
Number of extensions: 625775
Number of successful extensions: 1437
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1385
Number of HSP's gapped (non-prelim): 34
length of query: 417
length of database: 18,247,518
effective HSP length: 105
effective length of query: 312
effective length of database: 14,271,588
effective search space: 4452735456
effective search space used: 4452735456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.