Search of human proteins with 5453906

Search of human proteins with 5453906

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453906 CDP-diacylglycerol-inositol
3-phosphatidyltransferase [Homo sapiens]
         (213 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453906 CDP-diacylglycerol-inositol 3-phosphatidyltransferase...   429   e-120
gi|188536108 cardiolipin synthase 1 isoform 2 [Homo sapiens]           34   0.11 
gi|10092647 cardiolipin synthase 1 isoform 1 [Homo sapiens]            34   0.11 
gi|50726996 choline phosphotransferase 1 [Homo sapiens]                32   0.52 
gi|5174415 choline/ethanolaminephosphotransferase [Homo sapiens]       30   1.2  
gi|56118223 choline/ethanolaminephosphotransferase [Homo sapiens]      30   1.2  
gi|119943112 7-dehydrocholesterol reductase [Homo sapiens]             30   2.0  

>gi|5453906 CDP-diacylglycerol-inositol 3-phosphatidyltransferase
           [Homo sapiens]
          Length = 213

 Score =  429 bits (1102), Expect = e-120
 Identities = 213/213 (100%), Positives = 213/213 (100%)

Query: 1   MPDENIFLFVPNLIGYARIVFAIISFYFMPCCPLTASSFYLLSGLLDAFDGHAARALNQG 60
           MPDENIFLFVPNLIGYARIVFAIISFYFMPCCPLTASSFYLLSGLLDAFDGHAARALNQG
Sbjct: 1   MPDENIFLFVPNLIGYARIVFAIISFYFMPCCPLTASSFYLLSGLLDAFDGHAARALNQG 60

Query: 61  TRFGAMLDMLTDRCSTMCLLVNLALLYPGATLFFQISMSLDVASHWLHLHSSVVRGSESH 120
           TRFGAMLDMLTDRCSTMCLLVNLALLYPGATLFFQISMSLDVASHWLHLHSSVVRGSESH
Sbjct: 61  TRFGAMLDMLTDRCSTMCLLVNLALLYPGATLFFQISMSLDVASHWLHLHSSVVRGSESH 120

Query: 121 KMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFHFSEGPLVGSVGLFRMGLWVTA 180
           KMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFHFSEGPLVGSVGLFRMGLWVTA
Sbjct: 121 KMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFHFSEGPLVGSVGLFRMGLWVTA 180

Query: 181 PIALLKSLISVIHLITAARNMAALDAADRAKKK 213
           PIALLKSLISVIHLITAARNMAALDAADRAKKK
Sbjct: 181 PIALLKSLISVIHLITAARNMAALDAADRAKKK 213


>gi|188536108 cardiolipin synthase 1 isoform 2 [Homo sapiens]
          Length = 202

 Score = 33.9 bits (76), Expect = 0.11
 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 10 VPNLIGYARIVFA-IISFYFMPCCPLTASSFYLLSGLLDAFDGHAARA-LNQGTRFGAML 67
          +PN++   RI  A ++ +  +      A   + L+GL D  DG  AR   NQ +  G+ L
Sbjct: 10 IPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWANQRSALGSAL 69

Query: 68 DMLTDRCSTMCLLVNL 83
          D L D+     L V+L
Sbjct: 70 DPLADKILISILYVSL 85


>gi|10092647 cardiolipin synthase 1 isoform 1 [Homo sapiens]
          Length = 301

 Score = 33.9 bits (76), Expect = 0.11
 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 10  VPNLIGYARIVFA-IISFYFMPCCPLTASSFYLLSGLLDAFDGHAARA-LNQGTRFGAML 67
           +PN++   RI  A ++ +  +      A   + L+GL D  DG  AR   NQ +  G+ L
Sbjct: 109 IPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWANQRSALGSAL 168

Query: 68  DMLTDRCSTMCLLVNL 83
           D L D+     L V+L
Sbjct: 169 DPLADKILISILYVSL 184


>gi|50726996 choline phosphotransferase 1 [Homo sapiens]
          Length = 406

 Score = 31.6 bits (70), Expect = 0.52
 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%)

Query: 13  LIGYA-RIVFAIISFYFMPCCPLTASSF-YLLSGL-------LDAFDGHAARALNQGTRF 63
           L+G A  +V  ++   + P     A  + YLL  L       LDA DG  AR  N  +  
Sbjct: 68  LLGLAVNVVTTLVLISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPL 127

Query: 64  GAMLDMLTDRCSTMCLLVNLAL-----LYPGATLFFQ-ISMSLDVASHWLHLHSSVVR 115
           G + D   D  ST+ + V  ++      YP    F   I M +   +HW    S ++R
Sbjct: 128 GELFDHGCDSLSTVFMAVGASIAARLGTYPDWFFFCSFIGMFVFYCAHWQTYVSGMLR 185


>gi|5174415 choline/ethanolaminephosphotransferase [Homo sapiens]
          Length = 416

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 47/178 (26%), Positives = 62/178 (34%), Gaps = 34/178 (19%)

Query: 46  LDAFDGHAARALNQGTRFGAMLDMLTDRCSTM------CLLVNLAL-------------- 85
           LDA DG  AR  N  +  G + D   D  ST+      C+ V L                
Sbjct: 132 LDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPDWMFFCCFAGTF 191

Query: 86  --------LYPGATLFFQISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTS 137
                    Y   TL F I    +V    + +H   V G         S  PVL I    
Sbjct: 192 MFYCAHWQTYVSGTLRFGIIDVTEVQIFIIIMHLLAVIGGPPFWQ---SMIPVLNIQMKI 248

Query: 138 RPALFTLCAGNELFYCLLYLFHFSEGPLVGSVGLFRMGLWVTAPIALLKSLISVIHLI 195
            PAL T+     +F C  Y      G  VG  G    G  V +P   + S+I++  +I
Sbjct: 249 FPALCTV--AGTIFSCTNYFRVIFTGG-VGKNGSTIAGTSVLSPFLHIGSVITLAAMI 303


>gi|56118223 choline/ethanolaminephosphotransferase [Homo sapiens]
          Length = 416

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 47/178 (26%), Positives = 62/178 (34%), Gaps = 34/178 (19%)

Query: 46  LDAFDGHAARALNQGTRFGAMLDMLTDRCSTM------CLLVNLAL-------------- 85
           LDA DG  AR  N  +  G + D   D  ST+      C+ V L                
Sbjct: 132 LDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPDWMFFCCFAGTF 191

Query: 86  --------LYPGATLFFQISMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTS 137
                    Y   TL F I    +V    + +H   V G         S  PVL I    
Sbjct: 192 MFYCAHWQTYVSGTLRFGIIDVTEVQIFIIIMHLLAVIGGPPFWQ---SMIPVLNIQMKI 248

Query: 138 RPALFTLCAGNELFYCLLYLFHFSEGPLVGSVGLFRMGLWVTAPIALLKSLISVIHLI 195
            PAL T+     +F C  Y      G  VG  G    G  V +P   + S+I++  +I
Sbjct: 249 FPALCTV--AGTIFSCTNYFRVIFTGG-VGKNGSTIAGTSVLSPFLHIGSVITLAAMI 303


>gi|119943112 7-dehydrocholesterol reductase [Homo sapiens]
          Length = 475

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 4/37 (10%)

Query: 8   LFVPNLIGYARIVFAIISFYFMPC----CPLTASSFY 40
           L+  N++GYA   FA++  YF P     C  T + FY
Sbjct: 181 LWCANILGYAVSTFAMVKGYFFPTSARDCKFTGNFFY 217


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.142    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,181,754
Number of Sequences: 37866
Number of extensions: 275700
Number of successful extensions: 588
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 587
Number of HSP's gapped (non-prelim): 7
length of query: 213
length of database: 18,247,518
effective HSP length: 98
effective length of query: 115
effective length of database: 14,536,650
effective search space: 1671714750
effective search space used: 1671714750
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.