Search of human proteins with 5174529

Search of human proteins with 5174529

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174529 methionine adenosyltransferase II, alpha [Homo
sapiens]
         (395 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174529 methionine adenosyltransferase II, alpha [Homo sapiens]    799   0.0  
gi|4557737 methionine adenosyltransferase I, alpha [Homo sapiens]     699   0.0  
gi|24307899 Era-like 1 [Homo sapiens]                                  31   2.2  
gi|58801559 complement component 1, q subcomponent-like 3 [Homo ...    30   2.9  
gi|21361759 myotubularin related protein 8 [Homo sapiens]              30   2.9  
gi|149158714 Atg13-interacting protein [Homo sapiens]                  29   6.5  
gi|31542675 Atg13-interacting protein [Homo sapiens]                   29   6.5  
gi|160707881 formin 2 [Homo sapiens]                                   29   8.5  

>gi|5174529 methionine adenosyltransferase II, alpha [Homo sapiens]
          Length = 395

 Score =  799 bits (2064), Expect = 0.0
 Identities = 395/395 (100%), Positives = 395/395 (100%)

Query: 1   MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA 60
           MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA
Sbjct: 1   MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA 60

Query: 61  KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG 120
           KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG
Sbjct: 61  KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG 120

Query: 121 VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS 180
           VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS
Sbjct: 121 VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS 180

Query: 181 KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT 240
           KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT
Sbjct: 181 KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT 240

Query: 241 IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW 300
           IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
Sbjct: 241 IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW 300

Query: 301 VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI 360
           VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI
Sbjct: 301 VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI 360

Query: 361 VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY 395
           VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
Sbjct: 361 VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY 395


>gi|4557737 methionine adenosyltransferase I, alpha [Homo sapiens]
          Length = 395

 Score =  699 bits (1803), Expect = 0.0
 Identities = 333/395 (84%), Positives = 370/395 (93%)

Query: 1   MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA 60
           MNG ++G  +  + EG F+FTSESVGEGHPDKICDQISDAVLDAHL+QDP+AKVACETV 
Sbjct: 1   MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVC 60

Query: 61  KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG 120
           KTGM+LL GEITS A VDYQ+VVR+ +KHIGYDDS+KGFD+KTCNVLVALEQQSPDIAQ 
Sbjct: 61  KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC 120

Query: 121 VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS 180
           VHLDRNEED+GAGDQGLMFGYATDETEECMPLTI+LAHKLNA++A+LRR+G LPWLRPDS
Sbjct: 121 VHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDS 180

Query: 181 KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT 240
           KTQVTVQYMQD GAV+P+R+HTIVISVQH+E++ L+EMR ALKE+VI+AVVPAKYLDEDT
Sbjct: 181 KTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDT 240

Query: 241 IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW 300
           +YHLQPSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
Sbjct: 241 VYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW 300

Query: 301 VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI 360
           VAKSLVK GLCRRVLVQVSYAIGV+ PLSISIF YGTSQK+ERELL++V KNFDLRPGVI
Sbjct: 301 VAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVI 360

Query: 361 VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY 395
           VRDLDLKKPIYQ+TA YGHFGR  FPWEVP+KL +
Sbjct: 361 VRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF 395


>gi|24307899 Era-like 1 [Homo sapiens]
          Length = 437

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 1/66 (1%)

Query: 187 QYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQP 246
           QY+  +    P   H+ V++ Q  EE+C + +R+ L E  +   VP     +  ++   P
Sbjct: 321 QYLLTQAQPGPWEYHSAVLTSQTPEEICANIIREKLLEH-LPQEVPYNVQQKTAVWEEGP 379

Query: 247 SGRFVI 252
            G  VI
Sbjct: 380 GGELVI 385


>gi|58801559 complement component 1, q subcomponent-like 3 [Homo
           sapiens]
          Length = 255

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 16/44 (36%), Positives = 22/44 (50%)

Query: 254 GPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYA 297
           GP G+ G  GR+ +    G  G +  GA S   Y+ V + A YA
Sbjct: 88  GPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYA 131


>gi|21361759 myotubularin related protein 8 [Homo sapiens]
          Length = 704

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 15/54 (27%), Positives = 27/54 (50%), Gaps = 1/54 (1%)

Query: 336 GTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEV 389
           G  QK +RE L + +K   + P ++ R  D + P+Y+    YG     + P+ +
Sbjct: 441 GNCQK-DREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPSTVPYNI 493


>gi|149158714 Atg13-interacting protein [Homo sapiens]
          Length = 218

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 9/36 (25%), Positives = 23/36 (63%)

Query: 195 VLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAV 230
           V  ++VH + ++ + + ++C +++ + L EK+I  V
Sbjct: 121 VWTVKVHVVALATEQERQICREKVGEKLCEKIINIV 156


>gi|31542675 Atg13-interacting protein [Homo sapiens]
          Length = 218

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 9/36 (25%), Positives = 23/36 (63%)

Query: 195 VLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAV 230
           V  ++VH + ++ + + ++C +++ + L EK+I  V
Sbjct: 121 VWTVKVHVVALATEQERQICREKVGEKLCEKIINIV 156


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 1/50 (2%)

Query: 260 GLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVD-RSAAYAARWVAKSLVKG 308
           G  G+K +     G G  GGG  SGK  +K D R++ ++   + K+L KG
Sbjct: 38  GSGGKKALGKHGKGGGGGGGGGESGKKKSKSDSRASVFSNLRIRKNLSKG 87


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,926,743
Number of Sequences: 37866
Number of extensions: 652360
Number of successful extensions: 1620
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1614
Number of HSP's gapped (non-prelim): 8
length of query: 395
length of database: 18,247,518
effective HSP length: 104
effective length of query: 291
effective length of database: 14,309,454
effective search space: 4164051114
effective search space used: 4164051114
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.